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Veli-Matti Kähäri

Research Profile

Chemicals & Drugs

Anatomy

Disorders

Squamous Cell Carcinoma

Living Beings

Mouse

Physiology

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Anni Laine; Jean-Christophe Marine; Minna Niemelä; Mathias T Rosenfeldt; Kevin M Ryan; Owen J Sansom; Harri Sihto; Edward K Chan; Christophe Come; Gerard I Evan; Heikki Joensuu; Melissa R Junttila; Veli-Matti Kähäri; Pirkko-Liisa Kellokumpu-Lehtinen; Anchit Khanna; Aleksandra Zwolinska; Jukka Westermarck
Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.
Suvi-Katri Leivonen; Konstantinos Lazaridis; Andrew Chantry; Julie Decock; Dylan R Edwards; Veli-Matti Kähäri
TGF-β-elicited induction of tissue inhibitor of metalloproteinases (TIMP)-3 expression in fibroblasts involves complex interplay between Smad3, p38α, and ERK1/2.
Liisa Nissinen; Veli-Matti Kähäri
ADAMTS5: A New Player in the Vascular Field.

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2013: Anni Laine; Jean-Christophe Marine; Minna Niemelä; Mathias T Rosenfeldt; Kevin M Ryan; Owen J Sansom; Harri Sihto; Edward K Chan; Christophe Come; Gerard I Evan; Heikki Joensuu; Melissa R Junttila; Veli-Matti Kähäri; Pirkko-Liisa Kellokumpu-Lehtinen; Anchit Khanna; Aleksandra Zwolinska; Jukka Westermarck
Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.
Cancer discovery 2013;3(2):182-97.
2013: Suvi-Katri Leivonen; Konstantinos Lazaridis; Andrew Chantry; Julie Decock; Dylan R Edwards; Veli-Matti Kähäri
TGF-β-elicited induction of tissue inhibitor of metalloproteinases (TIMP)-3 expression in fibroblasts involves complex interplay between Smad3, p38α, and ERK1/2.
PloS one 2013;8(2):e57474.
2012: Liisa Nissinen; Veli-Matti Kähäri
ADAMTS5: A New Player in the Vascular Field.
The American journal of pathology 2012;181(3):743-5.
2012: Mervi J Toriseva; Olli Carpén; Masaki Inada; Stephen M Krane; Matti Laato; Suvi T Ruohonen; Eriika Savontaus; Veli-Matti Kähäri
MMP-13 regulates growth of wound granulation tissue and modulates gene expression signatures involved in inflammation, proteolysis, and cell viability.
PloS one 2012;7(8):e42596.
2012: Mervi J Toriseva; Risto Ala-Aho; Reidar Grénman; Juha Peltonen; Sirkku Peltonen; Veli-Matti Kähäri
Keratinocyte growth factor induces gene expression signature associated with suppression of malignant phenotype of cutaneous squamous carcinoma cells.
PloS one 2012;7(3):e33041.
2011: Mehdi Farshchian; Reidar Grénman; Ritva Heljasvaara; Markku Kallajoki; Atte Kivisaari; Juha Peltonen; Taina Pihlajaniemi; Pilvi Riihilä; Risto Ala-Aho; Veli-Matti Kähäri
Serpin peptidase inhibitor clade A member 1 (SerpinA1) is a novel biomarker for progression of cutaneous squamous cell carcinoma.
The American journal of pathology 2011;179(3):1110-9.
2011: Janne P Kallio; Sally Hopkins-Donaldson; Andrew H Baker; Veli-Matti Kähäri
TIMP-3 promotes apoptosis in nonadherent small cell lung carcinoma cells lacking functional death receptor pathway.
International journal of cancer. Journal international du cancer 2011;128(4):991-6.
2011: Hitoshi Endo; Johbu Itoh; Veli-Matti Kähäri; Kaori Kameyama; Maki Niioka; Isao Okazaki; Yoshihiko Sugioka; Risto Ala-Aho; Tetsu Watanabe
Matrix metalloproteinase-13 promotes recovery from experimental liver cirrhosis in rats.
Pathobiology : journal of immunopathology, molecular and cellular biology 2011;78(5):239-52.
2010: A K Kivisaari; Markku Kallajoki; Risto Ala-Aho; J A McGrath; Johann W Bauer; R Königová; M Medvecz; W Beckert; Reidar Grénman; Veli-Matti Kähäri
Matrix metalloproteinase-7 activates heparin-binding epidermal growth factor-like growth factor in cutaneous squamous cell carcinoma.
The British journal of dermatology 2010;163(4):726-35.
2010: Jarmo K Laihia; Janne P Kallio; Pekka Taimen; Harry Kujari; Veli-Matti Kähäri; Lasse Leino
Protodynamic intracellular acidification by cis-urocanic acid promotes apoptosis of melanoma cells in vitro and in vivo.
The Journal of investigative dermatology 2010;130(10):2431-9.
2010: Eugene Healy; vincent piguet; Veli-Matti Kähäri
Forty years of the European Society for Dermatological Research as European dermatology goes from strength to strength.
The Journal of investigative dermatology 2010;130(8):1957-9.
2010: Heikki Luukkaa; Pekka Klemi; Ilmo Leivo; Antti A Mäkitie; Jonathan Irish; Ralph Gilbert; Bayardo Perez-Ordonez; Pirkko Hirsimäki; Tero Vahlberg; Atte Kivisaari; Veli-Matti Kähäri; Reidar Grénman
Expression of matrix metalloproteinase-1, -7, -9, -13, Ki-67, and HER-2 in epithelial-myoepithelial salivary gland cancer.
Head & neck 2010;32(8):1019-27.
2010: Pekka T Heikkinen; Marika Nummela; Terhi Jokilehto; Reidar Grenman; Veli-Matti Kähäri; Panu M Jaakkola
Hypoxic conversion of SMAD7 function from an inhibitor into a promoter of cell invasion.
Cancer research 2010;70(14):5984-93.
2010: Angela Stokes; Juho Joutsa; Risto Ala-Aho; Mark Pitchers; Caroline J Pennington; Craig Martin; Don J Premachandra; Yasunori Okada; Juha Peltonen; Reidar Grénman; Helen A James; Dylan R Edwards; Veli-Matti Kähäri
Expression profiles and clinical correlations of degradome components in the tumor microenvironment of head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(7):2022-35.
2010: Pekka T Heikkinen; Marika Nummela; Suvi-Katri Leivonen; Jukka Westermarck; Caroline S Hill; Veli-Matti Kähäri; Panu M Jaakkola
Hypoxia-activated Smad3-specific dephosphorylation by PP2A.
The Journal of biological chemistry 2010;285(6):3740-9.
2010: Angela C Bradshaw; Alan L Parker; Margaret R Duffy; Lynda Coughlan; Nico van Rooijen; Veli-Matti Kähäri; Stuart A Nicklin; Andrew H Baker
Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X.
PLoS pathogens 2010;6(10):e1001142.
2010: Heikki Luukkaa; Pekka Klemi; Pirkko Hirsimäki; Tero Vahlberg; Atte Kivisaari; Veli-Matti Kähäri; Reidar Grénman
Matrix metalloproteinase (MMP)-7 in salivary gland cancer.
Acta oncologica (Stockholm, Sweden) 2010;49(1):85-90.
2009: Veli-Matti Kähäri; Risto Ala-Aho
Stromal collagenase in melanoma: a vascular connection.
The Journal of investigative dermatology 2009;129(11):2545-7.
2009: Sari Suomela; Outi Elomaa; Tiina Skoog; Risto Ala-Aho; Leila Jeskanen; Jenita Pärssinen; Leena Latonen; Reidar Grénman; Juha Kere; Veli-Matti Kähäri; Ulpu Saarialho-Kere
CCHCR1 is up-regulated in skin cancer and associated with EGFR expression.
PloS one 2009;4(6):e6030.
2009: Mervi J Toriseva; Veli-Matti Kähäri
Proteinases in cutaneous wound healing.
Cellular and molecular life sciences : CMLS 2009;66(2):203-24.
2009: Lotta Kangasniemi; M Koskinen; M Jokinen; M Toriseva; R Ala-Aho; Veli-Matti Kähäri; H Jalonen; Seppo Ylä-Herttuala; H Moilanen; Ulf-Hakan Stenman; I Diaconu; Anna Kanerva; S Pesonen; Tanja Hakkarainen; Akseli Hemminki
Extended release of adenovirus from silica implants in vitro and in vivo.
Gene therapy 2009;16(1):103-10.
2008: Pia Vihinen; Risto Ala-Aho; Veli-Matti Kähäri
Diagnostic and prognostic role of matrix metalloproteases in cancer.
Expert opinion on medical diagnostics 2008;2(9):1025-39.
2008: Attila Sebe; Suvi-Katri Leivonen; Attila Fintha; András Masszi; Laszlo Rosivall; Veli-Matti Kähäri; Istvan Mucsi
Transforming growth factor-beta-induced alpha-smooth muscle cell actin expression in renal proximal tubular cells is regulated by p38beta mitogen-activated protein kinase, extracellular signal-regulated protein kinase1,2 and the Smad signalling during epithelial-myofibroblast transdifferentiation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2008;23(5):1537-45.
2008: Heikki Luukkaa; Pekka Klemi; Pirkko Hirsimäki; Tero Vahlberg; Atte Kivisaari; Veli-Matti Kähäri; Reidar Grénman
Matrix metalloproteinase (MMP)-1, -9 and -13 as prognostic factors in salivary gland cancer.
Acta oto-laryngologica 2008;128(4):482-90.
2008: A K Kivisaari; Markku Kallajoki; Tuomas Mirtti; J A McGrath; Johann W Bauer; F Weber; R Königová; D Sawamura; K C Sato-Matsumura; H Shimizu; M Csikós; K Sinemus; W Beckert; Veli-Matti Kähäri
Transformation-specific matrix metalloproteinases (MMP)-7 and MMP-13 are expressed by tumour cells in epidermolysis bullosa-associated squamous cell carcinomas.
The British journal of dermatology 2008;158(4):778-85.
2007: Suvi-Katri Leivonen; Veli-Matti Kähäri
Transforming growth factor-beta signaling in cancer invasion and metastasis.
International journal of cancer. Journal international du cancer 2007;121(10):2119-24.
2007: Melissa R Junttila; Risto Ala-Aho; Terhi Jokilehto; Juha Peltonen; Markku Kallajoki; Reidar Grenman; Panu M Jaakkola; Jukka Westermarck; Veli-Matti Kähäri
p38alpha and p38delta mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells.
Oncogene 2007;26(36):5267-79.
2007: Risto Kajanne; Päivi J Miettinen; Annika Mehlem; Suvi-Katri Leivonen; Michael J Birrer; Marco Foschi; Veli-Matti Kähäri; Sirpa Leppä
EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways.
Journal of cellular physiology 2007;212(2):489-97.
2007: Melissa R Junttila; Pietri Puustinen; Minna Niemelä; Raija Ahola; Hugh Arnold; Trine Böttzauw; Risto Ala-Aho; Christina Nielsen; Johanna Ivaska; Yoichi Taya; Shi-Long Lu; Shujun Lin; Edward Chan; Xiao-Jing Wang; Reidar Grènman; Juergen Kast; Tuula Kallunki; Rosalie C Pelz; Veli-Matti Kähäri; Jukka Westermarck
CIP2A inhibits PP2A in human malignancies.
Cell 2007;130(1):51-62.
2007: Pia Vihinen; Johanna Hilli; Meri-Sisko Vuoristo; Kari J Syrjänen; Veli-Matti Kähäri; Seppo Pyrhönen
Serum VEGF-C is associated with metastatic site in patients with malignant melanoma.
Acta oncologica (Stockholm, Sweden) 2007;46(5):678-84.
2007: Mervi J Toriseva; Risto Ala-Aho; Jarkko Karvinen; Andrew H Baker; Varpu S Marjomäki; Jyrki Heino; Veli-Matti Kähäri
Collagenase-3 (MMP-13) enhances remodeling of three-dimensional collagen and promotes survival of human skin fibroblasts.
The Journal of investigative dermatology 2007;127(1):49-59.
2006: Mikko Rönty; Suvi-Katri Leivonen; Boris Hinz; Andrew Rachlin; Carol A Otey; Veli-Matti Kähäri; Olli Carpén
Isoform-specific regulation of the actin-organizing protein palladin during TGF-beta1-induced myofibroblast differentiation.
The Journal of investigative dermatology 2006;126(11):2387-96.
2006: Markus J V Vähä-Koskela; Janne P Kallio; Linda C Jansson; Jari E Heikkilä; Vasily A Zakhartchenko; Markku Kallajoki; Veli-Matti Kähäri; Ari E Hinkkanen
Oncolytic capacity of attenuated replicative semliki forest virus in human melanoma xenografts in severe combined immunodeficient mice.
Cancer research 2006;66(14):7185-94.
2006: Suvi-Katri Leivonen; Risto Ala-Aho; K Koli; Reidar Grénman; Juha Peltonen; Veli-Matti Kähäri
Activation of Smad signaling enhances collagenase-3 (MMP-13) expression and invasion of head and neck squamous carcinoma cells.
Oncogene 2006;25(18):2588-600.
2006: Marjaana Luukkaa; Pia Vihinen; Pauliina Kronqvist; Tero Vahlberg; Seppo Pyrhönen; Veli-Matti Kähäri; Reidar Grénman
Association between high collagenase-3 expression levels and poor prognosis in patients with head and neck cancer.
Head & neck 2006;28(3):225-34.
2006: Ilkka T Harvima; Annamari Ranki; Timo Reunala; Veli-Matti Kähäri; Aarne Oikarinen
[How should the care of dermatological diseases be developed?].
Duodecim; lääketieteellinen aikakauskirja 2006;122(4):479; author reply 480.
2006: Katsunori Shinozaki; E Suominen; Francine E Carrick; Bernhard V Sauter; Veli-Matti Kähäri; A Lieber; Savio L C Woo; Marja-Liisa Savontaus
Efficient infection of tumor endothelial cells by a capsid-modified adenovirus.
Gene therapy 2006;13(1):52-9.
2005: Kirsi Joronen; Veli-Matti Kähäri; Eero Vuorio
Temporospatial expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in mouse antigen-induced arthritis.
Histochemistry and cell biology 2005;124(6):535-45.
2005: Johanna Nikkola; Pia Vihinen; Meri-Sisko Vuoristo; Pirkko Kellokumpu-Lehtinen; Veli-Matti Kähäri; Seppo Pyrhönen
High serum levels of matrix metalloproteinase-9 and matrix metalloproteinase-1 are associated with rapid progression in patients with metastatic melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(14):5158-66.
2005: Suvi-Katri Leivonen; Lari Häkkinen; David Liu; Veli-Matti Kähäri
Smad3 and extracellular signal-regulated kinase 1/2 coordinately mediate transforming growth factor-beta-induced expression of connective tissue growth factor in human fibroblasts.
The Journal of investigative dermatology 2005;124(6):1162-9.
2005: Pia Vihinen; Risto Ala-Aho; Veli-Matti Kähäri
Matrix metalloproteinases as therapeutic targets in cancer.
Current cancer drug targets 2005;5(3):203-20.
2005: Ulla Impola; Leila Jeskanen; LS Ravanti; S Syrjänen; BT Baldursson; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Expression of matrix metalloproteinase (MMP)-7 and MMP-13 and loss of MMP-19 and p16 are associated with malignant progression in chronic wounds.
The British journal of dermatology 2005;152(4):720-6.
2005: Risto Ala-Aho; Veli-Matti Kähäri
Collagenases in cancer.
Biochimie 2005;87(3-4):273-86.
2004: Pirjo Koistinen; Matti Ahonen; Veli-Matti Kähäri; Jyrki Heino
alphaV integrin promotes in vitro and in vivo survival of cells in metastatic melanoma.
International journal of cancer. Journal international du cancer 2004;112(1):61-70.
2004: Risto Ala-Aho; Matti Ahonen; Sarah George; Jari Heikkilä; Reidar Grénman; Markku Kallajoki; Veli-Matti Kähäri
Targeted inhibition of human collagenase-3 (MMP-13) expression inhibits squamous cell carcinoma growth in vivo.
Oncogene 2004;23(30):5111-23.
2004: Kirsi Joronen; Risto Ala-Aho; Marja-Leena Majuri; H Alenius; Veli-Matti Kähäri; Eero Vuorio
Adenovirus mediated intra-articular expression of collagenase-3 (MMP-13) induces inflammatory arthritis in mice.
Annals of the rheumatic diseases 2004;63(6):656-64.
2004: Pia Vihinen; Veli-Matti Kähäri; Seppo Pyrhönen
[Prognostic factors and improving treatment of cutaneous melanoma].
Duodecim; lääketieteellinen aikakauskirja 2004;120(12):1445-56.
2003: Niina Hieta; Ulla Impola; Carlos López-Otín; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Matrix metalloproteinase-19 expression in dermal wounds and by fibroblasts in culture.
The Journal of investigative dermatology 2003;121(5):997-1004.
2003: Song-Ping Li; Melissa R Junttila; Jiahuai Han; Veli-Matti Kähäri; Jukka Westermarck
p38 Mitogen-activated protein kinase pathway suppresses cell survival by inducing dephosphorylation of mitogen-activated protein/extracellular signal-regulated kinase kinase1,2.
Cancer research 2003;63(13):3473-7.
2003: Matti Ahonen; Minna Poukkula; Andrew H Baker; Masahide Kashiwagi; Hideaki Nagase; John E Eriksson; Veli-Matti Kähäri
Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors.
Oncogene 2003;22(14):2121-34.
2003: Ulla Impola; Mervi J Toriseva; Sari Suomela; Leila Jeskanen; Niina Hieta; Tiina Jahkola; Reidar Grenman; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Matrix metalloproteinase-19 is expressed by proliferating epithelium but disappears with neoplastic dedifferentiation.
International journal of cancer. Journal international du cancer 2003;103(6):709-16.
2003: Pia Vihinen; Seppo Pyrhönen; Veli-Matti Kähäri
New prognostic factors and developing therapy of cutaneous melanoma.
Annals of medicine 2003;35(2):66-78.
2003: Erika Iivanainen; Veli-Matti Kähäri; Jyrki Heino; Klaus Elenius
Endothelial cell-matrix interactions.
Microscopy research and technique 2003;60(1):13-22.
2002: Suvi-Katri Leivonen; Andrew Chantry; Lari Häkkinen; Jiahuai Han; Veli-Matti Kähäri
Smad3 mediates transforming growth factor-beta-induced collagenase-3 (matrix metalloproteinase-13) expression in human gingival fibroblasts. Evidence for cross-talk between Smad3 and p38 signaling pathways.
The Journal of biological chemistry 2002;277(48):46338-46.
2002: Erja Kerkelä; Risto Ala-Aho; Pekka Klemi; Seija Grénman; Steven D Shapiro; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome.
The Journal of pathology 2002;198(2):258-69.
2002: Niina Reunanen; Song-Ping Li; Matti Ahonen; Marco Foschi; Jiahuai Han; Veli-Matti Kähäri
Activation of p38 alpha MAPK enhances collagenase-1 (matrix metalloproteinase (MMP)-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization.
The Journal of biological chemistry 2002;277(35):32360-8.
2002: Matti Ahonen; Risto Ala-Aho; Andrew H Baker; Sarah George; Reidar Grénman; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Antitumor activity and bystander effect of adenovirally delivered tissue inhibitor of metalloproteinases-3.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(6):705-15.
2002: Pia Vihinen; Veli-Matti Kähäri
Matrix metalloproteinases in cancer: prognostic markers and therapeutic targets.
International journal of cancer. Journal international du cancer 2002;99(2):157-66.
2002: Yasuji Mori; Veli-Matti Kähäri; john varga
Scleroderma-like cutaneous syndromes.
Current rheumatology reports 2002;4(2):113-22.
2002: Johanna Ivaska; Liisa Nissinen; Nina Immonen; John E Eriksson; Veli-Matti Kähäri; Jyrki Heino
Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.
Molecular and cellular biology 2002;22(5):1352-9.
2002: Risto Ala-Aho; Reidar Grénman; Prem Seth; Veli-Matti Kähäri
Adenoviral delivery of p53 gene suppresses expression of collagenase-3 (MMP-13) in squamous carcinoma cells.
Oncogene 2002;21(8):1187-95.
2002: Johanna Nikkola; Pia Vihinen; Tatyana Vlaykova; Marjo Hahka-Kemppinen; Veli-Matti Kähäri; Seppo Pyrhönen
High expression levels of collagenase-1 and stromelysin-1 correlate with shorter disease-free survival in human metastatic melanoma.
International journal of cancer. Journal international du cancer 2002;97(4):432-8.
2002: Zhi Chen; Matti Ahonen; Heli Hämäläinen; Jeffrey M Bergelson; Veli-Matti Kähäri; Riitta Lahesmaa
High-efficiency gene transfer to primary T lymphocytes by recombinant adenovirus vectors.
Journal of immunological methods 2002;260(1-2):79-89.
2002: Risto Ala-Aho; Nina Johansson; Andrew H Baker; Veli-Matti Kähäri
Expression of collagenase-3 (MMP-13) enhances invasion of human fibrosarcoma HT-1080 cells.
International journal of cancer. Journal international du cancer 2002;97(3):283-9.
2001: Hannele Uusitalo; Ari Hiltunen; Matti Ahonen; T J Gao; V Lefebvre; VR Harley; Veli-Matti Kähäri; Eero Vuorio
Accelerated up-regulation of L-Sox5, Sox6, and Sox9 by BMP-2 gene transfer during murine fracture healing.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(10):1837-45.
2001: S E F Tran; T H Holmstrom; Matti Ahonen; Veli-Matti Kähäri; John E Eriksson
MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors.
The Journal of biological chemistry 2001;276(19):16484-90.
2001: Mirva Söderström; Hannu T Aro; Matti Ahonen; Nina Johansson; Allan J Aho; Tauno O Ekfors; Tom Böhling; Veli-Matti Kähäri; Eero Vuorio
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human chondrosarcomas.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2001;109(4):305-15.
2001: Hannele Uusitalo; Juho Rantakokko; Matti Ahonen; Tapio Jämsä; J Tuukkanen; Veli-Matti Kähäri; Eero Vuorio; Hannu T Aro
A metaphyseal defect model of the femur for studies of murine bone healing.
Bone 2001;28(4):423-9.
2001: Hannele Uusitalo; Ari Hiltunen; Matti Ahonen; Veli-Matti Kähäri; Hannu T Aro; Eero Vuorio
Induction of periosteal callus formation by bone morphogenetic protein-2 employing adenovirus-mediated gene delivery.
Matrix biology : journal of the International Society for Matrix Biology 2001;20(2):123-7.
2001: Johanna Nikkola; Pia Vihinen; Tatyana Vlaykova; Marjo Hahka-Kemppinen; Veli-Matti Kähäri; Seppo Pyrhönen
High collagenase-1 expression correlates with a favourable chemoimmunotherapy response in human metastatic melanoma.
Melanoma research 2001;11(2):157-66.
2001: LS Ravanti; Mervi J Toriseva; Risto Penttinen; T Crombleholme; Marco Foschi; Jiahuai Han; Veli-Matti Kähäri
Expression of human collagenase-3 (MMP-13) by fetal skin fibroblasts is induced by transforming growth factor beta via p38 mitogen-activated protein kinase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(6):1098-100.
2001: Jukka Westermarck; Song-Ping Li; Tuula Kallunki; Jiahuai Han; Veli-Matti Kähäri
p38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression.
Molecular and cellular biology 2001;21(7):2373-83.
2001: Veijo Hukkanen; Veli-Matti Kähäri; Timo Hyypiä
[Viruses as helpful instruments in medicine].
Duodecim; lääketieteellinen aikakauskirja 2001;117(10):1059-65.
2001: Matti Laato; Jyrki Heino; B Gerdin; Veli-Matti Kähäri; Juha H A Niinikoski
Interferon-gamma-induced inhibition of wound healing in vivo and in vitro.
Annales chirurgiae et gynaecologiae 2001;90 Suppl 215():19-23.
2001: Matti Laato; Jyrki Heino; B Gerdin; Veli-Matti Kähäri; Juha H A Niinikoski
Interferon-gamma-induced inhibition of wound healing in vivo and in vitro.
Annales chirurgiae et gynaecologiae. Supplementum 2001;(215):19-23.
2000: Jukka Westermarck; S Li; Panu M Jaakkola; Tuula Kallunki; Reidar Grénman; Veli-Matti Kähäri
Activation of fibroblast collagenase-1 expression by tumor cells of squamous cell carcinomas is mediated by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase-2.
Cancer research 2000;60(24):7156-62.
2000: Lari Häkkinen; S Strassburger; Veli-Matti Kähäri; P G Scott; I Eichstetter; R V Lozzo; Hannu Larjava
A role for decorin in the structural organization of periodontal ligament.
Laboratory investigation; a journal of technical methods and pathology 2000;80(12):1869-80.
2000: Niina Reunanen; Marco Foschi; Jiahuai Han; Veli-Matti Kähäri
Activation of extracellular signal-regulated kinase 1/2 inhibits type I collagen expression by human skin fibroblasts.
The Journal of biological chemistry 2000;275(44):34634-9.
2000: PJ Boström; LS Ravanti; Niina Reunanen; Vesa Aaltonen; Karl-Ove Söderström; Veli-Matti Kähäri; Matti Laato
Expression of collagenase-3 (matrix metalloproteinase-13) in transitional-cell carcinoma of the urinary bladder.
International journal of cancer. Journal international du cancer 2000;88(3):417-23.
2000: Panu M Jaakkola; Matti Ahonen; Veli-Matti Kähäri; Markku Jalkanen
Transcriptional targeting of adenoviral gene delivery into migrating wound keratinocytes using FiRE, a growth factor-inducible regulatory element.
Gene therapy 2000;7(19):1640-7.
2000: Erika Ekholm; LS Ravanti; Veli-Matti Kähäri; P Paavolainen; Risto Penttinen
Expression of extracellular matrix genes: transforming growth factor (TGF)-beta1 and ras in tibial fracture healing of lathyritic rats.
Bone 2000;27(4):551-7.
2000: LS Ravanti; Veli-Matti Kähäri
Matrix metalloproteinases in wound repair (review).
International journal of molecular medicine 2000;6(4):391-407.
2000: Petri Laine; Niina Reunanen; LS Ravanti; Marco Foschi; M Santra; Renato V Iozzo; Veli-Matti Kähäri
Activation of extracellular signal-regulated protein kinase1,2 results in down-regulation of decorin expression in fibroblasts.
The Biochemical journal 2000;349(Pt 1):19-25.
2000: Erja Kerkelä; Risto Ala-Aho; Leila Jeskanen; O Rechardt; Reidar Grénman; Steven D Shapiro; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer.
The Journal of investigative dermatology 2000;114(6):1113-9.
2000: Kaija Inkinen; H Turakainen; Henrik Wolff; LS Ravanti; Veli-Matti Kähäri; Juhani Ahonen
Expression and activity of matrix metalloproteinase-2 and -9 in experimental granulation tissue.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2000;108(5):318-28.
2000: Nina Johansson; Matti Ahonen; Veli-Matti Kähäri
Matrix metalloproteinases in tumor invasion.
Cellular and molecular life sciences : CMLS 2000;57(1):5-15.
2000: Risto Ala-Aho; Nina Johansson; Reidar Grénman; N E Fusenig; Carlos López-Otín; Veli-Matti Kähäri
Inhibition of collagenase-3 (MMP-13) expression in transformed human keratinocytes by interferon-gamma is associated with activation of extracellular signal-regulated kinase-1,2 and STAT1.
Oncogene 2000;19(2):248-57.
2000: Andrew H Baker; Matti Ahonen; Veli-Matti Kähäri
Potential applications of tissue inhibitor of metalloproteinase (TIMP) overexpression for cancer gene therapy.
Advances in experimental medicine and biology 2000;465():469-83.
2000: Nina Johansson; Veli-Matti Kähäri
Matrix metalloproteinases in squamous cell carcinoma.
Histology and histopathology 2000;15(1):225-37.
2000: Nina Johansson; Risto Ala-Aho; Veli-Jukka Uitto; Reidar Grénman; N E Fusenig; Carlos López-Otín; Veli-Matti Kähäri
Expression of collagenase-3 (MMP-13) and collagenase-1 (MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogen-activated protein kinase.
Journal of cell science 2000;113 Pt 2():227-35.
1999: LS Ravanti; Lari Häkkinen; Hannu Larjava; Ulpu Saarialho-Kere; Marco Foschi; Jiahuai Han; Veli-Matti Kähäri
Transforming growth factor-beta induces collagenase-3 expression by human gingival fibroblasts via p38 mitogen-activated protein kinase.
The Journal of biological chemistry 1999;274(52):37292-300.
1999: Johanna Ivaska; Hilkka Reunanen; Jukka Westermarck; Leeni Koivisto; Veli-Matti Kähäri; Jyrki Heino
Integrin alpha2beta1 mediates isoform-specific activation of p38 and upregulation of collagen gene transcription by a mechanism involving the alpha2 cytoplasmic tail.
The Journal of cell biology 1999;147(2):401-16.
1999: Jukka Westermarck; Veli-Matti Kähäri
Regulation of matrix metalloproteinase expression in tumor invasion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(8):781-92.
1999: Veli-Matti Kähäri; Ulpu Saarialho-Kere
Matrix metalloproteinases and their inhibitors in tumour growth and invasion.
Annals of medicine 1999;31(1):34-45.
1999: Nina Johansson; MO Vaalamo; Seija Grénman; Sakari Hietanen; Pekka Klemi; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Collagenase-3 (MMP-13) is expressed by tumor cells in invasive vulvar squamous cell carcinomas.
The American journal of pathology 1999;154(2):469-80.
1999: LS Ravanti; Jyrki Heino; Carlos López-Otín; Veli-Matti Kähäri
Induction of collagenase-3 (MMP-13) expression in human skin fibroblasts by three-dimensional collagen is mediated by p38 mitogen-activated protein kinase.
The Journal of biological chemistry 1999;274(4):2446-55.
1998: Jukka Westermarck; Tim H Holmström; Matti Ahonen; John E Eriksson; Veli-Matti Kähäri
Enhancement of fibroblast collagenase-1 (MMP-1) gene expression by tumor promoter okadaic acid is mediated by stress-activated protein kinases Jun N-terminal kinase and p38.
Matrix biology : journal of the International Society for Matrix Biology 1998;17(8-9):547-57.
1998: Liisa Nissinen; Jukka Westermarck; Leeni Koivisto; Veli-Matti Kähäri; Jyrki Heino
Transcription of alpha2 integrin gene in osteosarcoma cells is enhanced by tumor promoters.
Experimental cell research 1998;243(1):1-10.
1998: Lassi Nelimarkka; Seppo T Nikkari; LS Ravanti; Veli-Matti Kähäri; Hannu Järveläinen
Collagenase-1, stromelysin-1 and 92 kDa gelatinase are associated with tumor necrosis factor-alpha induced morphological change of human endothelial cells in vitro.
Matrix biology : journal of the International Society for Matrix Biology 1998;17(4):293-304.
1998: Veli-Jukka Uitto; Karri Airola; MO Vaalamo; Nina Johansson; Edward E Putnins; James D Firth; J Salonen; Carlos López-Otín; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Collagenase-3 (matrix metalloproteinase-13) expression is induced in oral mucosal epithelium during chronic inflammation.
The American journal of pathology 1998;152(6):1489-99.
1998: Matti Ahonen; Andrew H Baker; Veli-Matti Kähäri
Adenovirus-mediated gene delivery of tissue inhibitor of metalloproteinases-3 inhibits invasion and induces apoptosis in melanoma cells.
Cancer research 1998;58(11):2310-5.
1998: Leena Mattila; Karri Airola; Matti Ahonen; Marja Hietarinta; C Black; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Activation of tissue inhibitor of metalloproteinases-3 (TIMP-3) mRNA expression in scleroderma skin fibroblasts.
The Journal of investigative dermatology 1998;110(4):416-21.
1998: Karri Airola; Matti Ahonen; Nina Johansson; P Heikkilä; Juha Kere; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Human TIMP-3 is expressed during fetal development, hair growth cycle, and cancer progression.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(4):437-47.
1998: K Isoherranen; Jukka Westermarck; Veli-Matti Kähäri; Christer T Jansén; Kari Punnonen
Differential regulation of the AP-1 family members by UV irradiation in vitro and in vivo.
Cellular signalling 1998;10(3):191-5.
1998: Niina Reunanen; Jukka Westermarck; Lari Häkkinen; Tim H Holmström; I Elo; John E Eriksson; Veli-Matti Kähäri
Enhancement of fibroblast collagenase (matrix metalloproteinase-1) gene expression by ceramide is mediated by extracellular signal-regulated and stress-activated protein kinase pathways.
The Journal of biological chemistry 1998;273(9):5137-45.
1998: Matti Ahonen; Andrew H Baker; Veli-Matti Kähäri
High level expression of tissue inhibitors of metalloproteinases-1,-2 and -3 in melanoma cells achieved by adenovirus mediated gene transfer.
Advances in experimental medicine and biology 1998;451():69-72.
1998: Veli-Matti Kähäri; Nina Johansson; Reidar Grénman; Karri Airola; Ulpu Saarialho-Kere
Expression of collagenase-3 (MMP-13) by tumor cells in squamous cell carcinomas of the head and neck.
Advances in experimental medicine and biology 1998;451():63-8.
1998: Lari Häkkinen; Jukka Westermarck; Nina Johansson; Heikki Aho; Juha Peltonen; Jyrki Heino; Veli-Matti Kähäri
Suprabasal expression of epidermal alpha 2 beta 1 and alpha 3 beta 1 integrins in skin treated with topical retinoic acid.
The British journal of dermatology 1998;138(1):29-36.
1997: john varga; Veli-Matti Kähäri
Eosinophilia-myalgia syndrome, eosinophilic fasciitis, and related fibrosing disorders.
Current opinion in rheumatology 1997;9(6):562-70.
1997: Veli-Matti Kähäri; Ulpu Saarialho-Kere
Matrix metalloproteinases in skin.
Experimental dermatology 1997;6(5):199-213.
1997: Nina Johansson; Karri Airola; Reidar Grénman; Arja-Leena Kariniemi; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Expression of collagenase-3 (matrix metalloproteinase-13) in squamous cell carcinomas of the head and neck.
The American journal of pathology 1997;151(2):499-508.
1997: Karri Airola; Nina Johansson; Arja-Leena Kariniemi; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Human collagenase-3 is expressed in malignant squamous epithelium of the skin.
The Journal of investigative dermatology 1997;109(2):225-31.
1997: MO Vaalamo; Leena Mattila; Nina Johansson; Arja-Leena Kariniemi; Marja-Liisa Karjalainen-Lindsberg; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds.
The Journal of investigative dermatology 1997;109(1):96-101.
1997: Jukka Westermarck; A Seth; Veli-Matti Kähäri
Differential regulation of interstitial collagenase (MMP-1) gene expression by ETS transcription factors.
Oncogene 1997;14(22):2651-60.
1997: Nina Johansson; Ulpu Saarialho-Kere; Karri Airola; R Herva; Liisa Nissinen; Jukka Westermarck; Eero Vuorio; Jyrki Heino; Veli-Matti Kähäri
Collagenase-3 (MMP-13) is expressed by hypertrophic chondrocytes, periosteal cells, and osteoblasts during human fetal bone development.
Developmental dynamics : an official publication of the American Association of Anatomists 1997;208(3):387-97.
1997: Nina Johansson; Jukka Westermarck; Sirpa Leppä; Lari Häkkinen; Leeni Koivisto; Carlos López-Otín; Juha Peltonen; Jyrki Heino; Veli-Matti Kähäri
Collagenase 3 (matrix metalloproteinase 13) gene expression by HaCaT keratinocytes is enhanced by tumor necrosis factor alpha and transforming growth factor beta.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(2):243-50.
1996: Lari Häkkinen; Jukka Westermarck; Veli-Matti Kähäri; Hannu Larjava
Human granulation-tissue fibroblasts show enhanced proteoglycan gene expression and altered response to TGF-beta 1.
Journal of dental research 1996;75(10):1767-78.
1996: Jouko Lohi; Kaisa Lehti; Jukka Westermarck; Veli-Matti Kähäri; Jorma Keski-Oja
Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate.
European journal of biochemistry / FEBS 1996;239(2):239-47.
1995: Jukka Westermarck; Lari Häkkinen; W Fiers; Veli-Matti Kähäri
TNF-R55-specific form of human tumor necrosis factor-alpha induces collagenase gene expression by human skin fibroblasts.
The Journal of investigative dermatology 1995;105(2):197-202.
1995: Jukka Westermarck; E Ilvonen; Veli-Matti Kähäri
The protein phosphatase inhibitor okadaic acid suppresses type I collagen gene expression in cultured fibroblasts at the transcriptional level.
The Biochemical journal 1995;308 ( Pt 3)():995-9.
1995: T Riikonen; Jukka Westermarck; Leeni Koivisto; A Broberg; Veli-Matti Kähäri; Jyrki Heino
Integrin alpha 2 beta 1 is a positive regulator of collagenase (MMP-1) and collagen alpha 1(I) gene expression.
The Journal of biological chemistry 1995;270(22):13548-52.
1995: Jukka Westermarck; E Ilvonen; J Uitto; Veli-Matti Kähäri
Suppression of elastin gene expression in dermal fibroblasts by protein phosphatase inhibitor okadaic acid.
Biochemical and biophysical research communications 1995;209(1):175-81.
1995: Veli-Matti Kähäri; Lari Häkkinen; Jukka Westermarck; Hannu Larjava
Differential regulation of decorin and biglycan gene expression by dexamethasone and retinoic acid in cultured human skin fibroblasts.
The Journal of investigative dermatology 1995;104(4):503-8.
1994: Jukka Westermarck; Jouko Lohi; Jorma Keski-Oja; Veli-Matti Kähäri
Okadaic acid-elicited transcriptional activation of collagenase gene expression in HT-1080 fibrosarcoma cells is mediated by JunB.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(11):1205-13.
1994: Veli-Matti Kähäri
Dexamethasone suppresses elastin gene expression in human skin fibroblasts in culture.
Biochemical and biophysical research communications 1994;201(3):1189-96.
1994: Jouko Lohi; Veli-Matti Kähäri; Jorma Keski-Oja
Cyclosporin A enhances cytokine and phorbol ester-induced fibroblast collagenase expression.
The Journal of investigative dermatology 1994;102(6):938-44.
1993: Veli-Matti Kähäri
Activation of dermal connective tissue in scleroderma.
Annals of medicine 1993;25(6):511-8.
1993: Alain Mauviel; Y Q Chen; Veli-Matti Kähäri; I Ledo; M Wu; L Rudnicka; J Uitto
Human recombinant interleukin-1 beta up-regulates elastin gene expression in dermal fibroblasts. Evidence for transcriptional regulation in vitro and in vivo.
The Journal of biological chemistry 1993;268(9):6520-4.
1992: Veli-Matti Kähäri; Y Q Chen; MM Bashir; Joel Rosenbloom; J Uitto
Tumor necrosis factor-alpha down-regulates human elastin gene expression. Evidence for the role of AP-1 in the suppression of promoter activity.
The Journal of biological chemistry 1992;267(36):26134-41.
1992: Alain Mauviel; Veli-Matti Kähäri; Markku T Kurkinen; C H Evans; J Uitto
Leukoregulin, a T-cell derived cytokine, upregulates stromelysin-1 gene expression in human dermal fibroblasts: evidence for the role of AP-1 in transcriptional activation.
Journal of cellular biochemistry 1992;50(1):53-61.
1992: Veli-Matti Kähäri; D R Olsen; R W Rhudy; P Carrillo; Y Q Chen; J Uitto
Transforming growth factor-beta up-regulates elastin gene expression in human skin fibroblasts. Evidence for post-transcriptional modulation.
Laboratory investigation; a journal of technical methods and pathology 1992;66(5):580-8.
1992: Alain Mauviel; Veli-Matti Kähäri; C H Evans; J Uitto
Transcriptional activation of fibroblast collagenase gene expression by a novel lymphokine, leukoregulin.
The Journal of biological chemistry 1992;267(8):5644-8.
1992: Alain Mauviel; Veli-Matti Kähäri; Y Q Chen; Markku T Kurkinen; C H Evans; J Uitto
Transcriptional activation of fibroblast stromelysin-1 and collagenase gene expression by a novel lymphokine, leukoregulin.
Transactions of the Association of American Physicians 1992;105():100-9.
1991: J Uitto; Angela M Christiano; Veli-Matti Kähäri; MM Bashir; Joel Rosenbloom
Molecular biology and pathology of human elastin.
Biochemical Society transactions 1991;19(4):824-9.
1991: M J Fazio; J O'Leary; Veli-Matti Kähäri; Y Q Chen; B Saitta; J Uitto
Human nidogen gene: structural and functional characterization of the 5'-flanking region.
The Journal of investigative dermatology 1991;97(2):281-5.
1991: Veli-Matti Kähäri; H Larjava; J Uitto
Differential regulation of extracellular matrix proteoglycan (PG) gene expression. Transforming growth factor-beta 1 up-regulates biglycan (PGI), and versican (large fibroblast PG) but down-regulates decorin (PGII) mRNA levels in human fibroblasts in culture.
The Journal of biological chemistry 1991;266(16):10608-15.
1991: Veli-Matti Kähäri; Juha Peltonen; Y Q Chen; J Uitto
Differential modulation of basement membrane gene expression in human fibrosarcoma HT-1080 cells by transforming growth factor-beta 1. Enhanced type IV collagen and fibronectin gene expression correlates with altered culture phenotype of the cells.
Laboratory investigation; a journal of technical methods and pathology 1991;64(6):807-18.
1991: T Vuorio; Veli-Matti Kähäri; C Black; Eero Vuorio
Expression of osteonectin, decorin, and transforming growth factor-beta 1 genes in fibroblasts cultured from patients with systemic sclerosis and morphea.
The Journal of rheumatology 1991;18(2):247-51.
1991: A Mauviel; J Heino; Veli-Matti Kähäri; D J Hartmann; G Loyau; Jean-Pierre Pujol; E Vuorio
Comparative effects of interleukin-1 and tumor necrosis factor-alpha on collagen production and corresponding procollagen mRNA levels in human dermal fibroblasts.
The Journal of investigative dermatology 1991;96(2):243-9.
1991: Joel Rosenbloom; MM Bashir; Heidi Yeh; J Rosenbloom; N Ornstein-Goldstein; M Fazio; Veli-Matti Kähäri; J Uitto
Regulation of elastin gene expression.
Annals of the New York Academy of Sciences 1991;624():116-36.
1991: Joel Rosenbloom; MM Bashir; Veli-Matti Kähäri; J Uitto
Elastin genes and regulation of their expression.
Critical reviews in eukaryotic gene expression 1991;1(3):145-56.
1991: Veli-Matti Kähäri; Sakari Reitamo; Håkan Granlund; J Uitto
[The fibrotic diseases of the skin].
Duodecim; lääketieteellinen aikakauskirja 1991;107(12):957-70.
1990: Veli-Matti Kähäri; Y Q Chen; M W Su; F Ramirez; J Uitto
Tumor necrosis factor-alpha and interferon-gamma suppress the activation of human type I collagen gene expression by transforming growth factor-beta 1. Evidence for two distinct mechanisms of inhibition at the transcriptional and posttranscriptional levels.
The Journal of clinical investigation 1990;86(5):1489-95.
1990: Veli-Matti Kähäri; M J Fazio; Y Q Chen; MM Bashir; Joel Rosenbloom; J Uitto
Deletion analyses of 5'-flanking region of the human elastin gene. Delineation of functional promoter and regulatory cis-elements.
The Journal of biological chemistry 1990;265(16):9485-90.
1990: Juha Peltonen; L Kähäri; S Jaakkola; Veli-Matti Kähäri; J Varga; J Uitto; Sergio A Jimenez
Evaluation of transforming growth factor beta and type I procollagen gene expression in fibrotic skin diseases by in situ hybridization.
The Journal of investigative dermatology 1990;94(3):365-71.
1990: M J Fazio; Veli-Matti Kähäri; MM Bashir; B Saitta; Joel Rosenbloom; J Uitto
Regulation of elastin gene expression: evidence for functional promoter activity in the 5'-flanking region of the human gene.
The Journal of investigative dermatology 1990;94(2):191-6.
1989: Matti Laato; Jyrki Heino; Veli-Matti Kähäri; Juha H A Niinikoski; B Gerdin
Epidermal growth factor (EGF) prevents methylprednisolone-induced inhibition of wound healing.
The Journal of surgical research 1989;47(4):354-9.
1989: Hannu Larjava; Jyrki Heino; Veli-Matti Kähäri; T Krusius; Eero Vuorio
Characterization of one phenotype of human periodontal granulation-tissue fibroblasts.
Journal of dental research 1989;68(1):20-5.
1989: Jyrki Heino; Veli-Matti Kähäri; S Jaakkola; Juha Peltonen
Collagen in the extracellular matrix of cultured scleroderma skin fibroblasts: changes related to ascorbic acid-treatment.
Matrix (Stuttgart, Germany) 1989;9(1):34-9.
1988: Jyrki Heino; Veli-Matti Kähäri; A Mauviel; T Krusius
Human recombinant interleukin-1 regulates cellular mRNA levels of dermatan sulphate proteoglycan core protein.
The Biochemical journal 1988;252(1):309-12.
1988: Veli-Matti Kähäri; M Sandberg; Hannu Kalimo; T Vuorio; Eero Vuorio
Identification of fibroblasts responsible for increased collagen production in localized scleroderma by in situ hybridization.
The Journal of investigative dermatology 1988;90(5):664-70.
1988: A Mauviel; Veli-Matti Kähäri; J Heino; M Daireaux; D J Hartmann; G Loyau; Jean-Pierre Pujol
Gene expression of fibroblast matrix proteins is altered by indomethacin.
FEBS letters 1988;231(1):125-9.
1988: Veli-Matti Kähäri; Jyrki Heino; T Vuorio; Eero Vuorio
Interferon-alpha and interferon-gamma reduce excessive collagen synthesis and procollagen mRNA levels of scleroderma fibroblasts in culture.
Biochimica et biophysica acta 1988;968(1):45-50.
1988: Veli-Matti Kähäri; E Eerola; Eero Vuorio
Flow cytometry of fibroblasts cultured from skin of patients with localized scleroderma.
Dermatologica 1988;177(6):348-53.
1987: Matti Laato; Veli-Matti Kähäri; Juha H A Niinikoski; Eero Vuorio
Epidermal growth factor increases collagen production in granulation tissue by stimulation of fibroblast proliferation and not by activation of procollagen genes.
The Biochemical journal 1987;247(2):385-8.
1987: Veli-Matti Kähäri; J Heino; E Vuorio
Interleukin-1 increases collagen production and mRNA levels in cultured skin fibroblasts.
Biochimica et biophysica acta 1987;929(2):142-7.
1987: Veli-Matti Kähäri; P Multimäki; E Vuorio
Elevated pro alpha 2(I) collagen mRNA levels in cultured scleroderma fibroblasts result from an increased transcription rate of the corresponding gene.
FEBS letters 1987;215(2):331-4.
1987: J Mäkinen; Veli-Matti Kähäri; K O Söderström; E Vuorio; T Hirvonen
Collagen synthesis in the vaginal connective tissue of patients with and without uterine prolapse.
European journal of obstetrics, gynecology, and reproductive biology 1987;24(4):319-25.
1987: T Vuorio; J K Mäkelä; Veli-Matti Kähäri; Eero Vuorio
Coordinated regulation of type I and type III collagen production and mRNA levels of pro alpha 1(I) and pro alpha 2(I) collagen in cultured morphea fibroblasts.
Archives of dermatological research 1987;279(3):154-60.
1987: Veli-Matti Kähäri; J Heino; H Larjava; E Vuorio
Alterations in scleroderma fibroblast surface glycoproteins associated with increased collagen synthesis.
Acta dermato-venereologica 1987;67(3):199-205.
1984: Veli-Matti Kähäri; T Vuorio; K Näntö-Salonen; Eero Vuorio
Increased type I collagen mRNA levels in cultured scleroderma fibroblasts.
Biochimica et biophysica acta 1984;781(1-2):183-6.
1984: T K Vuorio; Veli-Matti Kähäri; A Lehtonen; E I Vuorio
Fibroblast activation in scleroderma.
Scandinavian journal of rheumatology 1984;13(3):229-37.