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Ralph Budd

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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T-Lymphocyte Subsets

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Co-Publications
Name
21
Russell, Jennifer
9
Roessner, Karen
9
Fortner, Karen
7
Tschopp, Jürg
5
Shi, Cuixia
5
Sigal, Leonard
4
Sobel, Burton
3
Schneider, David
3
Misra, Ravi
3
Dohrman, Austin
3
Huber, Sally
3
Kennedy, NJ
3
Wolfe, Julie
2
Taatjes, Douglas
2
Flavell, Richard

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Publications

TOP 3
Anathy Vikas; Aesif Scott W; Guala Amy S; Havermans Marije; Reynaert Niki L; Ho Ye-Shih; Budd Ralph C; Janssen-Heininger Yvonne M W
Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas.
Koenig A; Russell J Q; Rodgers W A; Budd R C
Spatial differences in active caspase-8 defines its role in T-cell activation versus cell death.
Collins Cheryl; Shi Cuixia; Russell Jennifer Q; Fortner Karen A; Budd Ralph C
Activation of gamma delta T cells by Borrelia burgdorferi is indirect via a TLR- and caspase-dependent pathway.

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All Publications

2009: Anathy Vikas; Aesif Scott W; Guala Amy S; Havermans Marije; Reynaert Niki L; Ho Ye-Shih; Budd Ralph C; Janssen-Heininger Yvonne M W
Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas.
The Journal of cell biology 2009;184(2):241-52.
2008: Koenig A; Russell J Q; Rodgers W A; Budd R C
Spatial differences in active caspase-8 defines its role in T-cell activation versus cell death.
Cell death and differentiation 2008;15(11):1701-11.
2008: Collins Cheryl; Shi Cuixia; Russell Jennifer Q; Fortner Karen A; Budd Ralph C
Activation of gamma delta T cells by Borrelia burgdorferi is indirect via a TLR- and caspase-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(4):2392-8.
2008: Sobel Burton E; Zaman Tarikuz; Budd Ralph C; Schneider David J; Taatjes Douglas J
Attenuation of apoptosis and the eye of the beholder.
Coronary artery disease 2008;19(1):55-8.
2008: Hughes Peter D; Belz Gabrielle T; Fortner Karen A; Budd Ralph C; Strasser Andreas; Bouillet Philippe
Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity.
Immunity 2008;28(2):197-205.
2008: Hinshaw-Makepeace Jennifer; Huston Gail; Fortner Karen A; Russell Jennifer Q; Holoch Daniel; Swain Susan; Budd Ralph C
c-FLIP(S) reduces activation of caspase and NF-kappaB pathways and decreases T cell survival.
European journal of immunology 2008;38(1):54-63.
2008: Taatjes Douglas J; Sobel Burton E; Budd Ralph C
Morphological and cytochemical determination of cell death by apoptosis.
Histochemistry and cell biology 2008;129(1):33-43.
2007: Misra Ravi S; Russell Jennifer Q; Koenig Andreas; Hinshaw-Makepeace Jennifer A; Wen Renren; Wang Demin; Huo Hairong; Littman Dan R; Ferch Uta; Ruland Jurgen; Thome Margot; Budd Ralph C
Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.
The Journal of biological chemistry 2007;282(27):19365-74.
2007: Peter Marcus E; Budd Ralph C; Desbarats Julie; Hedrick Stephen M; Hueber Anne-Odile; Newell M Karen; Owen Laurie B; Pope Richard M; Tschopp Juerg; Wajant Harald; Wallach David; Wiltrout Robert H; Zörnig Martin; Lynch David H
The CD95 receptor: apoptosis revisited.
Cell 2007;129(3):447-50.
2007: Dienz Oliver; Eaton Sheri M; Krahl Troy J; Diehl Sean; Charland Colette; Dodge John; Swain Susan L; Budd Ralph C; Haynes Laura; Rincon Mercedes
Accumulation of NFAT mediates IL-2 expression in memory, but not naïve, CD4+ T cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(17):7175-80.
2006: Huber Sally; Dohrman Austin; Sartini Danielle; Budd Ralph C
Reduced myocarditis following Coxsackievirus infection in cellular FLICE inhibitory protein--long form-transgenic mice.
Immunology 2006;119(4):541-50.
2006: Chen Yabing; Budd Ralph C; Kelm Robert J; Sobel Burton E; Schneider David J
Augmentation of proliferation of vascular smooth muscle cells by plasminogen activator inhibitor type 1.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(8):1777-83.
2006: Wu Wenfang; Misra Ravi S; Russell Jennifer Q; Flavell Richard A; Rincón Mercedes; Budd Ralph C
Proteolytic regulation of nuclear factor of activated T (NFAT) c2 cells and NFAT activity by caspase-3.
The Journal of biological chemistry 2006;281(16):10682-90.
2006: Budd Ralph C; Yeh Wen-Chen; Tschopp Jürg
cFLIP regulation of lymphocyte activation and development.
Nature reviews. Immunology 2006;6(3):196-204.
2006: Shi Cuixia; Wolfe Julie; Russell Jennifer Q; Fortner Karen; Hardin Nicholas; Anguita Juan; Budd Ralph C
Fas ligand deficiency impairs host inflammatory response against infection with the spirochete Borrelia burgdorferi.
Infection and immunity 2006;74(2):1156-60.
2005: Collins Cheryl; Wolfe Julie; Roessner Karen; Shi Cuixia; Sigal Leonard H; Budd Ralph C
Lyme arthritis synovial gammadelta T cells instruct dendritic cells via fas ligand.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):5656-65.
2005: Fortner Karen A; Budd Ralph C
The death receptor Fas (CD95/APO-1) mediates the deletion of T lymphocytes undergoing homeostatic proliferation.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4374-82.
2005: Dohrman Austin; Russell Jennifer Q; Cuenin Solange; Fortner Karen; Tschopp Jürg; Budd Ralph C
Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(1):311-8.
2005: Dohrman Austin; Kataoka Takao; Cuenin Solange; Russell Jennifer Q; Tschopp Jurg; Budd Ralph C
Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5270-8.
2005: Misra Ravi S; Jelley-Gibbs Dawn M; Russell Jennifer Q; Huston Gail; Swain Susan L; Budd Ralph C
Effector CD4+ T cells generate intermediate caspase activity and cleavage of caspase-8 substrates.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):3999-4009.
2004: Shrivastava Punya; Pantano Cristen; Watkin Richard; McElhinney Brian; Guala Amy; Poynter Matthew L; Persinger Rebecca L; Budd Ralph; Janssen-Heininger Yvonne
Reactive nitrogen species-induced cell death requires Fas-dependent activation of c-Jun N-terminal kinase.
Molecular and cellular biology 2004;24(15):6763-72.
2004: Chen Yabing; Kelm Robert J; Budd Ralph C; Sobel Burton E; Schneider David J
Inhibition of apoptosis and caspase-3 in vascular smooth muscle cells by plasminogen activator inhibitor type-1.
Journal of cellular biochemistry 2004;92(1):178-88.
2004: Wu Wenfang; Rinaldi Lisa; Fortner Karen A; Russell Jennifer Q; Tschopp Jürg; Irvin Charles; Budd Ralph C
Cellular FLIP long form-transgenic mice manifest a Th2 cytokine bias and enhanced allergic airway inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(8):4724-32.
2003: Roessner Karen; Wolfe Julie; Shi Cuixia; Sigal Leonard H; Huber Sally; Budd Ralph C
High expression of Fas ligand by synovial fluid-derived gamma delta T cells in Lyme arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2702-10.
2002: Lens Susanne M A; Kataoka Takao; Fortner Karen A; Tinel Antoine; Ferrero Isabel; MacDonald Robson H; Hahne Michel; Beermann Friedrich; Attinger Antoine; Orbea Hans-Acha; Budd Ralph C; Tschopp Jürg
The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes.
Molecular and cellular biology 2002;22(15):5419-33.
2002: Huber Sally; Shi Cuixia; Budd Ralph C
Gammadelta T cells promote a Th1 response during coxsackievirus B3 infection in vivo: role of Fas and Fas ligand.
Journal of virology 2002;76(13):6487-94.
2002: Budd Ralph C
Death receptors couple to both cell proliferation and apoptosis.
The Journal of clinical investigation 2002;109(4):437-41.
2001: Kennedy N J; Russell J Q; Michail N; Budd R C
Liver damage by infiltrating CD8+ T cells is Fas dependent.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6654-62.
2001: Budd R C
Activation-induced cell death.
Current opinion in immunology 2001;13(3):356-62.
2000: Kataoka T; Budd R C; Holler N; Thome M; Martinon F; Irmler M; Burns K; Hahne M; Kennedy N; Kovacsovics M; Tschopp J
The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways.
Current biology : CB 2000;10(11):640-8.
1999: Kennedy N J; Kataoka T; Tschopp J; Budd R C
Caspase activation is required for T cell proliferation.
The Journal of experimental medicine 1999;190(12):1891-6.
1999: Wilson D J; Alessandrini A; Budd R C
MEK1 activation rescues Jurkat T cells from Fas-induced apoptosis.
Cellular immunology 1999;194(1):67-77.
1999: Mixter P F; Russell J Q; Morrissette G J; Charland C; Aleman-Hoey D; Budd R C
A model for the origin of TCR-alphabeta+ CD4-CD8- B220+ cells based on high affinity TCR signals.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(10):5747-56.
1999: Huber S A; Budd R C; Rossner K; Newell M K
Apoptosis in coxsackievirus B3-induced myocarditis and dilated cardiomyopathy.
Annals of the New York Academy of Sciences 1999;887():181-90.
1998: Vincent M S; Roessner K; Sellati T; Huston C D; Sigal L H; Behar S M; Radolf J D; Budd R C
Lyme arthritis synovial gamma delta T cells respond to Borrelia burgdorferi lipoproteins and lipidated hexapeptides.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(10):5762-71.
1998: Russell J Q; Morrissette G J; Weidner M; Vyas C; Aleman-Hoey D; Budd R C
Liver damage preferentially results from CD8(+) T cells triggered by high affinity peptide antigens.
The Journal of experimental medicine 1998;188(6):1147-57.
1998: Russell J Q; Mooney T; Cohen P L; MacPherson B; Noelle R J; Budd R C
Anti-CD40L accelerates renal disease and adenopathy in MRL-lpr mice in parallel with decreased thymocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(2):729-39.
1998: Kennedy N J; Budd R C
Phosphorylation of FADD/MORT1 and Fas by kinases that associate with the membrane-proximal cytoplasmic domain of Fas.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(10):4881-8.
1998: Roessner K; Trivedi H; Gaur L; Howard D; Aversa J; Cooper S M; Sigal L H; Budd R C
Biased T-cell antigen receptor repertoire in Lyme arthritis.
Infection and immunity 1998;66(3):1092-9.
1998: Fortner K A; Russell J Q; Budd R C
Down-modulation of CD2 delays deletion of superantigen-responsive T cells.
European journal of immunology 1998;28(1):70-9.
1997: Budd R C
An overview of apoptosis.
Coronary artery disease 1997;8(10):593-7.
1996: Melton E; Sarner N; Torkar M; van der Merwe P A; Russell J Q; Budd R C; Mamalaki C; Tolaini M; Kioussis D; Zamoyska R
Transgene-encoded human CD2 acts in a dominant negative fashion to modify thymocyte selection signals in mice.
European journal of immunology 1996;26(12):2952-63.
1996: Vincent M S; Roessner K; Lynch D; Wilson D; Cooper S M; Tschopp J; Sigal L H; Budd R C
Apoptosis of Fashigh CD4+ synovial T cells by borrelia-reactive Fas-ligand(high) gamma delta T cells in Lyme arthritis.
The Journal of experimental medicine 1996;184(6):2109-17.
1996: Wilson D J; Fortner K A; Lynch D H; Mattingly R R; Macara I G; Posada J A; Budd R C
JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells.
European journal of immunology 1996;26(5):989-94.
1995: Budd R C; Mixter P F
The origin of CD4-CD8-TCR alpha beta+ thymocytes: a model based on T-cell receptor avidity.
Immunology today 1995;16(9):428-31.
1995: Cooper S M; Roessner K D; Naito-Hoopes M; Dobbs C; Nicklas J A; Howard D B; Gaur L K; Budd R C
Unstimulated rheumatoid synovial T-cells have a consistent V beta gene bias when compared to peripheral blood T-cells.
Annals of the New York Academy of Sciences 1995;756():186-9.
1995: Clements J L; Cooper S M; Budd R C
Abnormal regulation of the IL-2 promoter in lpr CD4-CD8- T lymphocytes results in constitutive expression of a novel nuclear factor of activated T cells-binding factor.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(12):6372-81.
1995: Mixter P F; Russell J Q; Durie F H; Budd R C
Decreased CD4-CD8- TCR-alpha beta + cells in lpr/lpr mice lacking beta 2-microglobulin.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(5):2063-74.
1994: Mixter P F; Russell J Q; Budd R C
Delayed kinetics of T lymphocyte anergy and deletion in lpr mice.
Journal of autoimmunity 1994;7(6):697-710.
1994: Cooper S M; Roessner K D; Naito-Hoopes M; Howard D B; Gaur L K; Budd R C
Increased usage of V beta 2 and V beta 6 in rheumatoid synovial fluid T cells.
Arthritis and rheumatism 1994;37(11):1627-36.
1994: Clements J L; Wolfe J; Cooper S M; Budd R C
Reversal of hyporesponsiveness in lpr CD4-CD8- T cells is achieved by induction of cell cycling and normalization of CD2 and p59fyn expression.
European journal of immunology 1994;24(3):558-65.
1994: Budd R C; Van Houten N; Clements J; Mixter P F
Parallels in T lymphocyte development between lpr and normal mice.
Seminars in immunology 1994;6(1):43-8.
1994: Van Houten N; Budd R C
Introduction: lessons from the lpr mouse--T lymphocyte development.
Seminars in immunology 1994;6(1):1-2.
1994: Roessner K; Fikrig E; Russell J Q; Cooper S M; Flavell R A; Budd R C
Prominent T lymphocyte response to Borrelia burgdorferi from peripheral blood of unexposed donors.
European journal of immunology 1994;24(2):320-4.
1993: Clements J L; Winslow G; Donahue C; Cooper S M; Allison J P; Budd R C
Co-stimulation via CD28 induces activation of a refractory subset of MRL-lpr/lpr T lymphocytes.
International immunology 1993;5(11):1451-60.
1993: Landolfi M M; Van Houten N; Russell J Q; Scollay R; Parnes J R; Budd R C
CD2-CD4-CD8- lymph node T lymphocytes in MRL lpr/lpr mice are derived from a CD2+CD4+CD8+ thymic precursor.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(2):1086-96.
1993: Van Houten N; Mixter P F; Wolfe J; Budd R C
CD2 expression on murine intestinal intraepithelial lymphocytes is bimodal and defines proliferative capacity.
International immunology 1993;5(6):665-72.
1992: Van Houten N; Budd R C
Accelerated programmed cell death of MRL-lpr/lpr T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(7):2513-7.
1992: Budd R C; Russell J Q; van Houten N; Cooper S M; Yagita H; Wolfe J
CD2 expression correlates with proliferative capacity of alpha beta + or gamma delta + CD4-CD8- T cells in lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(4):1055-64.
1991: Cooper S M; Dier D L; Roessner K D; Budd R C; Nicklas J A
Diversity of rheumatoid synovial tissue T cells by T cell receptor analysis. Oligoclonal expansion in interleukin-2-responsive cells.
Arthritis and rheumatism 1991;34(5):537-46.
1991: Budd R C; Schumacher J H; Winslow G; Mosmann T R
Elevated production of interferon-gamma and interleukin 4 by mature T cells from autoimmune lpr mice correlates with Pgp-1 (CD44) expression.
European journal of immunology 1991;21(4):1081-4.
1990: Budd R C; Winslow G; Inokuchi S; Imboden J B
Intact antigen receptor-mediated generation of inositol phosphates and increased intracellular calcium in CD4 CD8 T lymphocytes from MRL lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(9):2862-72.
1990: Morel P A; Horn G T; Budd R C; Erlich H A; Fathman C G
Shared molecular markers of genetic predisposition to seropositive rheumatoid arthritis.
Human immunology 1990;27(2):90-9.
1989: Butterfield K; Fathman C G; Budd R C
A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1.
The Journal of experimental medicine 1989;169(4):1461-6.

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