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Azim Mohamedali

Research Profile

Disorders

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Single Nucleotide Polymorphism

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Austin G Kulasekararaj; Nicholas C Lea; Judith C Marsh; Syed A Mian; Azim Mohamedali; Barbara Czepulkowski; Joop Gäken; Robin Ireland; Pramila Krishnamurthy; Coralie Pennaneach; Sabine Pomplun; Alexander E Smith; Ghulam J Mufti
TP53 mutations in myelodysplastic syndrome are strongly correlated with aberrations of chromosome 5, and correlate with adverse prognosis.
Rachel H Westbrook; Nigel D Heaton; Michael A Heneghan; Nicholas C Lea; Azim Mohamedali; John G O'Grady; David W Orr; Lara N Roberts; Alexander E Smith; Julia Wendon; Ghulam J Mufti
Prevalence and clinical outcomes of the 46/1 haplotype, Janus kinase 2 mutations, and ten-eleven translocation 2 mutations in Budd-Chiari syndrome and their impact on thrombotic complications post liver transplantation.
Andres Jerez; Seiji Kojima; Austin G Kulasekararaj; Alan List; Jacqueline Boultwood; Anna Jankowska; Hideki Makishima; A MICHAEL MCDEVITT; Kathy McGraw; Azim Mohamedali; Alison R Moliterno; Ghulam J Mufti; Hideki Muramatsu; Christine L O'Keefe; Andrea Pellagatti; Bartlomiej Przychodzen; Mikkael A Sekeres; Yuka Sugimoto; Ramon Tiu; Amit Verma; Valeria Visconte; Jaroslaw P Maciejewski
Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis.

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All Publications

2013: Austin G Kulasekararaj; Nicholas C Lea; Judith C Marsh; Syed A Mian; Azim Mohamedali; Barbara Czepulkowski; Joop Gäken; Robin Ireland; Pramila Krishnamurthy; Coralie Pennaneach; Sabine Pomplun; Alexander E Smith; Ghulam J Mufti
TP53 mutations in myelodysplastic syndrome are strongly correlated with aberrations of chromosome 5, and correlate with adverse prognosis.
British journal of haematology 2013;160(5):660-72.
2012: Rachel H Westbrook; Nigel D Heaton; Michael A Heneghan; Nicholas C Lea; Azim Mohamedali; John G O'Grady; David W Orr; Lara N Roberts; Alexander E Smith; Julia Wendon; Ghulam J Mufti
Prevalence and clinical outcomes of the 46/1 haplotype, Janus kinase 2 mutations, and ten-eleven translocation 2 mutations in Budd-Chiari syndrome and their impact on thrombotic complications post liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2012;18(7):819-27.
2012: Andres Jerez; Seiji Kojima; Austin G Kulasekararaj; Alan List; Jacqueline Boultwood; Anna Jankowska; Hideki Makishima; A MICHAEL MCDEVITT; Kathy McGraw; Azim Mohamedali; Alison R Moliterno; Ghulam J Mufti; Hideki Muramatsu; Christine L O'Keefe; Andrea Pellagatti; Bartlomiej Przychodzen; Mikkael A Sekeres; Yuka Sugimoto; Ramon Tiu; Amit Verma; Valeria Visconte; Jaroslaw P Maciejewski
Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis.
Blood 2012;119(25):6109-17.
2012: Joop Gäken; Jie Jiang; Austin G Kulasekararaj; Farooq Malik; Azim Mohamedali; Alexander E Smith; Doris Stangl; Mahvash Tavassoli; N Shaun B Thomas; Constantinos Chronis; Farzin Farzaneh; Ghulam J Mufti
A functional assay for microRNA target identification and validation.
Nucleic acids research 2012;40(10):e75.
2012: Andres Jerez; Denise A S Batista; Lukasz Gondek; Anna Jankowska; Hideki Makishima; A MICHAEL MCDEVITT; Azim Mohamedali; Ghulam J Mufti; Christine L O'Keefe; Bartlomiej Przychodzen; Mikkael A Sekeres; Ramon Tiu; Jaroslaw P Maciejewski
Topography, clinical, and genomic correlates of 5q myeloid malignancies revisited.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(12):1343-9.
2012: Shahram Kordasti; Austin G Kulasekararaj; Judith Marsh; Syed A Mian; Azim Mohamedali; Pilar Perez Abellan; Sufyan Al-Khan; Nana Benson-Quarm; Benedetta Costantini; Farzin Farzaneh; Jie Jiang; Thomas Seidl; Alexander Smith; Caroline Veen; Ghulam J Mufti
Functional characterization of CD4+ T cells in aplastic anemia.
Blood 2012;119(9):2033-43.
2011: Ramon Tiu; Lukasz Gondek; Christine L O'Keefe; Paul Elson; Jungwon Huh; Azim Mohamedali; Austin Kulasekararaj; Anjali Advani; Ronald Paquette; Alan F List; Mikkael A Sekeres; A MICHAEL MCDEVITT; Ghulam J Mufti; Jaroslaw P Maciejewski
Prognostic impact of SNP array karyotyping in myelodysplastic syndromes and related myeloid malignancies.
Blood 2011;117(17):4552-60.
2010: Alexander E Smith; Azim Mohamedali; Austin Kulasekararaj; Ziyi Lim; Joop Gäken; Nicholas C Lea; Bartlomiej Przychodzen; Syed A Mian; Erick E Nasser; Claire Shooter; Nigel B Westwood; Corinna Strupp; Norbert Gattermann; Jaroslaw P Maciejewski; Ulrich Germing; Ghulam J Mufti
Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value.
Blood 2010;116(19):3923-32.
2009: Azim Mohamedali; Alexander E Smith; Joop Gaken; Nicholas C Lea; Syed A Mian; Nigel B Westwood; Corinna Strupp; Norbert Gattermann; Ulrich Germing; Ghulam J Mufti
Novel TET2 mutations associated with UPD4q24 in myelodysplastic syndrome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(24):4002-6.
2009: Azim Mohamedali; Barbara-ann Guinn; Satyajit Sahu; N Shaun B Thomas; Ghulam J Mufti
Serum profiling reveals distinctive proteomic markers in chronic myeloid leukaemia patients.
British journal of haematology 2009;144(2):263-5.
2009: Azim Mohamedali; Ghulam J Mufti
Van-den Berghe's 5q- syndrome in 2008.
British journal of haematology 2009;144(2):157-68.
2008: Azim Mohamedali; Nicholas C Lea; Roger M Feakins; Kavita Raj; Ghulam J Mufti; Hemant M Kocher
AKT1 (E17K) mutation in pancreatic cancer.
Technology in cancer research & treatment 2008;7(5):407-8.
2007: Nader Omidvar; Scott C Kogan; Stephanie Beurlet; Carole le Pogam; Anne Janin; Robert R West; Maria-Elena Noguera; Murielle Reboul; Annie Soulie; Christophe Leboeuf; Niclas Setterblad; Dean W Felsher; Eric Lagasse; Azim Mohamedali; N Shaun B Thomas; Pierre Fenaux; Michaela Fontenay; Marika Pla; Ghulam J Mufti; Irving Weissman; Christine Chomienne; Rose Ann Padua
BCL-2 and mutant NRAS interact physically and functionally in a mouse model of progressive myelodysplasia.
Cancer research 2007;67(24):11657-67.
2007: Azim Mohamedali; Joop Gäken; Natalie A Twine; Wendy Ingram; Nigel B Westwood; Nicholas C Lea; Janet Hayden; Nora Donaldson; Carlo Aul; Norbert Gattermann; Aristotle Giagounidis; Ulrich Germing; Alan F List; Ghulam J Mufti
Prevalence and prognostic significance of allelic imbalance by single-nucleotide polymorphism analysis in low-risk myelodysplastic syndromes.
Blood 2007;110(9):3365-73.
2007: Barbara Guinn; Azim Mohamedali; N Shaun B Thomas; Ken Mills
Immunotherapy of myeloid leukaemia.
Cancer immunology, immunotherapy : CII 2007;56(7):943-57.
2007: Barbara Guinn; Azim Mohamedali; Ken Mills; Barbara Czepulkowski; Michael Schmitt; Jochen Greiner
Leukemia associated antigens: their dual role as biomarkers and immunotherapeutic targets for acute myeloid leukemia.
Biomarker insights 2007;2():69-79.
2006: M M Ceesay; Nicholas C Lea; Wendy Ingram; Nigel B Westwood; Joop Gäken; Azim Mohamedali; J Cervera; Ulrich Germing; Norbert Gattermann; Aristotle Giagounidis; Z Garcia-Casado; G Sanz; Ghulam J Mufti
The JAK2 V617F mutation is rare in RARS but common in RARS-T.
Leukemia 2006;20(11):2060-1.
2006: Inês Soeiro; Azim Mohamedali; Hanna M Romanska; Nicholas C Lea; Emma S Child; Janet Glassford; Stephen J Orr; Claudia Roberts; Kikkeri N Naresh; El-Nasir Lalani; David J Mann; Roger J Watson; N Shaun B Thomas; Eric W-F Lam
p27Kip1 and p130 cooperate to regulate hematopoietic cell proliferation in vivo.
Molecular and cellular biology 2006;26(16):6170-84.
2006: Nicholas C Lea; Ziyi Lim; Nigel B Westwood; Matthew Arno; Joop Gäken; Azim Mohamedali; Ghulam J Mufti
Presence of JAK2 V617F tyrosine kinase mutation as a myeloid-lineage-specific mutation in chronic neutrophilic leukaemia.
Leukemia 2006;20(7):1324-6.
2006: Wendy Ingram; Nicholas C Lea; J Cervera; Ulrich Germing; Pierre Fenaux; Bruno Cassinat; Jean-Jacques Kiladjian; Judit Várkonyi; P Antunovic; Nigel B Westwood; Matthew Arno; Azim Mohamedali; J Gaken; T Kontou; Barbara Czepulkowski; N A Twine; J Tamaska; J Csomer; S Benedek; Norbert Gattermann; E Zipperer; Aristotle Giagounidis; Z Garcia-Casado; G Sanz; Ghulam J Mufti
The JAK2 V617F mutation identifies a subgroup of MDS patients with isolated deletion 5q and a proliferative bone marrow.
Leukemia 2006;20(7):1319-21.
2004: Azim Mohamedali; François Moreau-Gaudry; Emmanuel Richard; Ping Xia; Jan A Nolta; Punam Malik
Self-inactivating lentiviral vectors resist proviral methylation but do not confer position-independent expression in hematopoietic stem cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(2):249-59.
2003: Azim Mohamedali; Inês Soeiro; Nicholas C Lea; Janet Glassford; Lolita Banerji; Ghulam J Mufti; Eric W-F Lam; N Shaun B Thomas
Cyclin D2 controls B cell progenitor numbers.
Journal of leukocyte biology 2003;74(6):1139-43.
2003: James Kettering; Azim Mohamedali; Lora M Green; Daila S Gridley
IL-2 gene and antisense TGF-beta1 strategies counteract HSV-2 transformed tumor progression.
Technology in cancer research & treatment 2003;2(3):211-21.