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Gregory Pazour

Research Profile

Anatomy

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Molecular Sequence Data

Genes & Molecular Sequences

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Publications

TOP 3
John A Follit; Gregory Pazour
Analysis of ciliary membrane protein dynamics using SNAP technology.
Benjamin D Engel; Stefan Geimer; Masafumi Hirono; Hiroaki Ishikawa; Ritsu Kamiya; Gregory Pazour; Ken-ichi Wakabayashi; Kimberly A Wemmer; George B Witman; Branch Craige; Wallace F Marshall
The role of retrograde intraflagellar transport in flagellar assembly, maintenance, and function.
Brian T Keady; Cecilia W Lo; John A Follit; Julie A Jonassen; Rajeev Samtani; Jovenal T San Agustin; Ramiah Subramanian; Kimimasa Tobita; Maiko Tsuchya; Gregory Pazour
IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport.

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All Publications

2013: John A Follit; Gregory Pazour
Analysis of ciliary membrane protein dynamics using SNAP technology.
Methods in enzymology 2013;524():195-204.
2012: Benjamin D Engel; Stefan Geimer; Masafumi Hirono; Hiroaki Ishikawa; Ritsu Kamiya; Gregory Pazour; Ken-ichi Wakabayashi; Kimberly A Wemmer; George B Witman; Branch Craige; Wallace F Marshall
The role of retrograde intraflagellar transport in flagellar assembly, maintenance, and function.
The Journal of cell biology 2012;199(1):151-67.
2012: Brian T Keady; Cecilia W Lo; John A Follit; Julie A Jonassen; Rajeev Samtani; Jovenal T San Agustin; Ramiah Subramanian; Kimimasa Tobita; Maiko Tsuchya; Gregory Pazour
IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport.
Developmental cell 2012;22(5):940-51.
2012: Julie A Jonassen; Stephen P Baker; Jovenal SanAgustin; Gregory Pazour
Disruption of IFT complex A causes cystic kidneys without mitotic spindle misorientation.
Journal of the American Society of Nephrology : JASN 2012;23(4):641-51.
2011: Erik F Y Hom; Ritsu Kamiya; Susan K Dutcher; Elizabeth H Harris; David R Mitchell; Gregory Pazour; Mary E Porter; Winfield S Sale; Maureen Wirschell; George B Witman; Toshiki Yagi; Stephen M King
A unified taxonomy for ciliary dyneins.
Cytoskeleton (Hoboken, N.J.) 2011;68(10):555-65.
2011: Brian T Keady; Yun Zheng Le; Gregory Pazour
IFT20 is required for opsin trafficking and photoreceptor outer segment development.
Molecular biology of the cell 2011;22(7):921-30.
2010: John A Follit; Lixia Li; Yvonne Vucica; Gregory Pazour
The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.
The Journal of cell biology 2010;188(1):21-8.
2009: Karl-Ferdinand Lechtreck; Eric C Johnson; Tsuyoshi Sakai; Deborah Cochran; Bryan A Ballif; John Rush; Gregory Pazour; Mitsuo Ikebe; George B Witman
The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella.
The Journal of cell biology 2009;187(7):1117-32.
2009: Christian A Clement; Stine G Kristensen; Kjeld Møllgård; Gregory Pazour; Bradley K Yoder; Lars A Larsen; Søren T Christensen
The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation.
Journal of cell science 2009;122(Pt 17):3070-82.
2009: John A Follit; Fenghui Xu; Brian T Keady; Gregory Pazour
Characterization of mouse IFT complex B.
Cell motility and the cytoskeleton 2009;66(8):457-68.
2008: John A Follit; Jovenal T San Agustin; Fenghui Xu; Julie A Jonassen; Rajeev Samtani; Cecilia W Lo; Gregory Pazour
The Golgin GMAP210/TRIP11 anchors IFT20 to the Golgi complex.
PLoS genetics 2008;4(12):e1000315.
2008: Julie A Jonassen; Jovenal T San Agustin; John A Follit; Gregory Pazour
Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease.
The Journal of cell biology 2008;183(3):377-84.
2008: Christopher A Tanner; Panteleimon Rompolas; Ramila S Patel-King; Oksana Gorbatyuk; Ken-ichi Wakabayashi; Gregory Pazour; Stephen M King
Three members of the LC8/DYNLL family are required for outer arm dynein motor function.
Molecular biology of the cell 2008;19(9):3724-34.
2008: Katherine Luby-Phelps; Joseph Fogerty; Sheila A Baker; Gregory Pazour; Joseph C Besharse
Spatial distribution of intraflagellar transport proteins in vertebrate photoreceptors.
Vision research 2008;48(3):413-23.
2007: Kaiyao Huang; Dennis R Diener; Aaron Mitchell; Gregory Pazour; George B Witman; Joel L Rosenbaum
Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella.
The Journal of cell biology 2007;179(3):501-14.
2007: Brian Palenik; Jane Grimwood; Andrea Aerts; Pierre Rouzé; Asaf Salamov; Nicholas Putnam; Chris Dupont; Richard Jorgensen; Evelyne Derelle; Stephane Marcel Rombauts; Kemin Zhou; Robert Otillar; Sabeeha S Merchant; Sheila Podell; Terry Gaasterland; Carolyn Napoli; Karla Gendler; Andrea Manuell; Vera Tai; Olivier Vallon; Gwenael Piganeau; Séverine Jancek; Marc heijde; Kamel Jabbari; Chris Bowler; Martin Lohr; Steven Robbens; Gregory Werner; Inna Dubchak; Gregory Pazour; Qinghu Ren; Ian Paulsen; Chuck Delwiche; Jeremy Schmutz; Daniel Rokhsar; Yves Van de Peer; Hervé Moreau; Igor V Grigoriev
The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7705-10.
2007: Yuqing Hou; Hongmin Qin; John A Follit; Gregory Pazour; Joel L Rosenbaum; George B Witman
Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella.
The Journal of cell biology 2007;176(5):653-65.
2006: Manfred Fliegauf; Judit Horvath; Christian von Schnakenburg; Heike Olbrich; Dominik Müller; Julia Thumfart; Bernhard Schermer; Gregory Pazour; Hartmut P H Neumann; Hanswalter Zentgraf; Thomas Benzing; Heymut Omran
Nephrocystin specifically localizes to the transition zone of renal and respiratory cilia and photoreceptor connecting cilia.
Journal of the American Society of Nephrology : JASN 2006;17(9):2424-33.
2006: John A Follit; Richard A Tuft; Kevin E Fogarty; Gregory Pazour
The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly.
Molecular biology of the cell 2006;17(9):3781-92.
2006: Meral Gunay-Aygun; Ellis D Avner; Robert L Bacallao; Peter L Choyke; Joseph T Flynn; Gregory G Germino; Lisa M Guay-Woodford; Peter Harris; Theo Heller; Julie R Ingelfinger; Frederick J Kaskel; Robert Kleta; Nicholas F LaRusso; Parvathi Mohan; Gregory Pazour; Benjamin L Shneider; Vicente E Torres; Patricia Wilson; Colleen Zak; Jing Zhou; William A Gahl
Autosomal recessive polycystic kidney disease and congenital hepatic fibrosis: summary statement of a first National Institutes of Health/Office of Rare Diseases conference.
The Journal of pediatrics 2006;149(2):159-64.
2006: Pinfen Yang; Dennis R Diener; Chun Yang; Takahiro Kohno; Gregory Pazour; Jennifer M Dienes; Nathan S Agrin; Stephen M King; Winfield S Sale; Ritsu Kamiya; Joel L Rosenbaum; George B Witman
Radial spoke proteins of Chlamydomonas flagella.
Journal of cell science 2006;119(Pt 6):1165-74.
2006: Gregory Pazour; Nathan S Agrin; B L Walker; George B Witman
Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes.
Journal of medical genetics 2006;43(1):62-73.
2005: Linda M DiBella; Oksana Gorbatyuk; Miho Sakato; Ken-ichi Wakabayashi; Ramila S Patel-King; Gregory Pazour; George B Witman; Stephen M King
Differential light chain assembly influences outer arm dynein motor function.
Molecular biology of the cell 2005;16(12):5661-74.
2005: Linda Schneider; Christian A Clement; Stefan Cuoni Teilmann; Gregory Pazour; Else Hoffmann; Peter Satir; Søren T Christensen
PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts.
Current biology : CB 2005;15(20):1861-6.
2005: Stefan Cuoni Teilmann; Anne Grete Byskov; Per A Pedersen; Denys N Wheatley; Gregory Pazour; Søren T Christensen
Localization of transient receptor potential ion channels in primary and motile cilia of the female murine reproductive organs.
Molecular reproduction and development 2005;71(4):444-52.
2005: Gregory Pazour; Nathan S Agrin; John Leszyk; George B Witman
Proteomic analysis of a eukaryotic cilium.
The Journal of cell biology 2005;170(1):103-13.
2004: Gregory Pazour
Intraflagellar transport and cilia-dependent renal disease: the ciliary hypothesis of polycystic kidney disease.
Journal of the American Society of Nephrology : JASN 2004;15(10):2528-36.
2004: E Virginia Armbrust; John A Berges; Chris Bowler; Beverley R Green; Diego Martinez; Nicholas Putnam; Shiguo Zhou; Andrew E Allen; Kirk E Apt; Michael Bechner; Mark A Brzezinski; Balbir K Chaal; Anthony Chiovitti; Aubrey K Davis; Mark S Demarest; J Chris Detter; Tijana Glavina; David Goodstein; Masood Z Hadi; Uffe Hellsten; Mark Hildebrand; Bethany D Jenkins; Jerzy Jurka; Vladimir V Kapitonov; Nils Kroger; Winnie W Y Lau; Todd W Lane; Frank W Larimer; J Casey Lippmeier; Susan Lucas; Mónica Medina; Anton Montsant; Miroslav Obornik; Micaela Schnitzler Parker; Brian Palenik; Gregory Pazour; Paul M Richardson; Tatiana A Rynearson; Mak A Saito; David C Schwartz; Kimberlee Thamatrakoln; Klaus Valentin; Assaf Vardi; Frances P Wilkerson; Daniel S Rokhsar
The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and metabolism.
Science (New York, N.Y.) 2004;306(5693):79-86.
2004: Linda M DiBella; Miho Sakato; Ramila S Patel-King; Gregory Pazour; Stephen M King
The LC7 light chains of Chlamydomonas flagellar dyneins interact with components required for both motor assembly and regulation.
Molecular biology of the cell 2004;15(10):4633-46.
2004: Yuqing Hou; Gregory Pazour; George B Witman
A dynein light intermediate chain, D1bLIC, is required for retrograde intraflagellar transport.
Molecular biology of the cell 2004;15(10):4382-94.
2004: Agata Jurczyk; Adam Gromley; Sambra Redick; Jovenal T San Agustin; George B Witman; Gregory Pazour; Dorien J M Peters; Stephen J Doxsey
Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly.
The Journal of cell biology 2004;166(5):637-43.
2004: Zhaoxia Sun; Adam Amsterdam; Gregory Pazour; Douglas Cole; Mark S Miller; Nancy Hopkins
A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney.
Development (Cambridge, England) 2004;131(16):4085-93.
2004: Gregory Pazour
Comparative genomics: prediction of the ciliary and basal body proteome.
Current biology : CB 2004;14(14):R575-7.
2004: David A Cano; Noel S Murcia; Gregory Pazour; Matthias Hebrok
Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization.
Development (Cambridge, England) 2004;131(14):3457-67.
2004: Maureen Wirschell; Gregory Pazour; Akinori Yoda; Masafumi Hirono; Ritsu Kamiya; George B Witman
Oda5p, a novel axonemal protein required for assembly of the outer dynein arm and an associated adenylate kinase.
Molecular biology of the cell 2004;15(6):2729-41.
2003: Sheila A Baker; Katie Freeman; Katherine Luby-Phelps; Gregory Pazour; Joseph C Besharse
IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia.
The Journal of biological chemistry 2003;278(36):34211-8.
2003: Diane M Casey; Kazuo Inaba; Gregory Pazour; Saeko Takada; Ken-ichi Wakabayashi; Curtis G Wilkerson; Ritsu Kamiya; George B Witman
DC3, the 21-kDa subunit of the outer dynein arm-docking complex (ODA-DC), is a novel EF-hand protein important for assembly of both the outer arm and the ODA-DC.
Molecular biology of the cell 2003;14(9):3650-63.
2003: Gregory Pazour; George B Witman
The vertebrate primary cilium is a sensory organelle.
Current opinion in cell biology 2003;15(1):105-10.
2003: Joseph C Besharse; Sheila A Baker; Katherine Luby-Phelps; Gregory Pazour
Photoreceptor intersegmental transport and retinal degeneration: a conserved pathway common to motile and sensory cilia.
Advances in experimental medicine and biology 2003;533():157-64.
2002: Saul Purton; Gregory Pazour
Meeting report: Tenth International Conference on the Cell and Molecular Biology of Chlamydomonas.
Protist 2002;153(4):325-36.
2002: Gregory Pazour; Joel L Rosenbaum
Intraflagellar transport and cilia-dependent diseases.
Trends in cell biology 2002;12(12):551-5.
2002: Gregory Pazour; Jovenal T San Agustin; John A Follit; Joel L Rosenbaum; George B Witman
Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease.
Current biology : CB 2002;12(11):R378-80.
2002: Gregory Pazour; Sheila A Baker; James A Deane; Douglas Cole; Bethany L Dickert; Joel L Rosenbaum; George B Witman; Joseph C Besharse
The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance.
The Journal of cell biology 2002;157(1):103-13.
2000: Gregory Pazour; George B Witman
Forward and reverse genetic analysis of microtubule motors in Chlamydomonas.
Methods (San Diego, Calif.) 2000;22(4):285-98.
2000: Gregory Pazour; Bethany L Dickert; Y Vucica; E S Seeley; Joel L Rosenbaum; George B Witman; Douglas Cole
Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella.
The Journal of cell biology 2000;151(3):709-18.
1999: Gregory Pazour; A Koutoulis; Sharon E Benashski; Bethany L Dickert; H Sheng; Ramila S Patel-King; Stephen M King; George B Witman
LC2, the chlamydomonas homologue of the t complex-encoded protein Tctex2, is essential for outer dynein arm assembly.
Molecular biology of the cell 1999;10(10):3507-20.
1999: C J Horst; D J Fishkind; Gregory Pazour; George B Witman
An insertional mutant of Chlamydomonas reinhardtii with defective microtubule positioning.
Cell motility and the cytoskeleton 1999;44(2):143-54.
1999: Gregory Pazour; Bethany L Dickert; George B Witman
The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly.
The Journal of cell biology 1999;144(3):473-81.
1998: Gregory Pazour; Curtis G Wilkerson; George B Witman
A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT).
The Journal of cell biology 1998;141(4):979-92.
1997: A Koutoulis; Gregory Pazour; Curtis G Wilkerson; K Inaba; H Sheng; Saeko Takada; George B Witman
The Chlamydomonas reinhardtii ODA3 gene encodes a protein of the outer dynein arm docking complex.
The Journal of cell biology 1997;137(5):1069-80.
1995: Gregory Pazour; O A Sineshchekov; George B Witman
Mutational analysis of the phototransduction pathway of Chlamydomonas reinhardtii.
The Journal of cell biology 1995;131(2):427-40.
1995: Curtis G Wilkerson; Stephen M King; A Koutoulis; Gregory Pazour; George B Witman
The 78,000 M(r) intermediate chain of Chlamydomonas outer arm dynein isa WD-repeat protein required for arm assembly.
The Journal of cell biology 1995;129(1):169-78.
1995: A G Moss; Gregory Pazour; George B Witman
Assay of Chlamydomonas phototaxis.
Methods in cell biology 1995;47():281-7.
1992: Gregory Pazour; C N Ta; Anath Das
Constitutive mutations of Agrobacterium tumefaciens transcriptional activator virG.
Journal of bacteriology 1992;174(12):4169-74.
1991: Gregory Pazour; C N Ta; Anath Das
Mutants of Agrobacterium tumefaciens with elevated vir gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(16):6941-5.
1990: Gregory Pazour; Anath Das
Characterization of the VirG binding site of Agrobacterium tumefaciens.
Nucleic acids research 1990;18(23):6909-13.
1990: M Mersereau; Gregory Pazour; Anath Das
Efficient transformation of Agrobacterium tumefaciens by electroporation.
Gene 1990;90(1):149-51.
1990: Gregory Pazour; Anath Das
virG, an Agrobacterium tumefaciens transcriptional activator, initiates translation at a UUG codon and is a sequence-specific DNA-binding protein.
Journal of bacteriology 1990;172(3):1241-9.
1989: Anath Das; Gregory Pazour
Delineation of the regulatory region sequences of Agrobacterium tumefaciens virB operon.
Nucleic acids research 1989;17(12):4541-50.
1989: P Sen; Gregory Pazour; D Anderson; Anath Das
Cooperative binding of Agrobacterium tumefaciens VirE2 protein to single-stranded DNA.
Journal of bacteriology 1989;171(5):2573-80.