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Lars ´Gustafsson

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Linda Björkhem-Bergman; Eduardo Diogene; Brian Godman; Malena Jirlow; Richard Laing; Rickard E Malmström; Oyvind Melien; Sabine Vogler; Eva Andersén-Karlsson; Lars ´Gustafsson
Interface management of pharmacotherapy. Joint hospital and primary care drug recommendations.
Gunnar Alván; Marine L Andersson; Annika B Asplund; Ylva Böttiger; Carl-Eric Elwin; Lars ´Gustafsson; Birgitta Ohman; E Törnqvist
The continuing challenge of providing drug information services to diminish the knowledge-practice gap in medical practice.
Karin C Söderberg Löfdal; Marine L Andersson; Lars ´Gustafsson
Cytochrome p450-mediated changes in oxycodone pharmacokinetics/pharmacodynamics and their clinical implications.

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2013: Linda Björkhem-Bergman; Eduardo Diogene; Brian Godman; Malena Jirlow; Richard Laing; Rickard E Malmström; Oyvind Melien; Sabine Vogler; Eva Andersén-Karlsson; Lars ´Gustafsson
Interface management of pharmacotherapy. Joint hospital and primary care drug recommendations.
European journal of clinical pharmacology 2013;69 Suppl 1():73-8.
2013: Gunnar Alván; Marine L Andersson; Annika B Asplund; Ylva Böttiger; Carl-Eric Elwin; Lars ´Gustafsson; Birgitta Ohman; E Törnqvist
The continuing challenge of providing drug information services to diminish the knowledge-practice gap in medical practice.
European journal of clinical pharmacology 2013;69 Suppl 1():65-72.
2013: Karin C Söderberg Löfdal; Marine L Andersson; Lars ´Gustafsson
Cytochrome p450-mediated changes in oxycodone pharmacokinetics/pharmacodynamics and their clinical implications.
Drugs 2013;73(6):533-43.
2012: S Nanzigu; Olof Beck; J Eriksen; Lars ´Gustafsson; R Kiguba; S Lanke; Q Ma; Margarita Mahindi; Fredrick Makumbi; G D Morse; paul waako
Pharmacokinetics of the nonnucleoside reverse transcriptase inhibitor efavirenz among HIV-infected Ugandans.
HIV medicine 2012;13(4):193-201.
2011: Lars ´Gustafsson; Björn Wettermark; Brian Godman; Eva Andersén-Karlsson; Ulf Bergman; Jan Hasselström; Lars-Olof Hensjö; Paul Hjemdahl; Ingrid Jägre; Margaretha Julander; Bo Ringertz; Daniel Schmidt; Susan Sjöberg; Folke Sjöqvist; Carl-Olav Stiller; Elisabeth Törnqvist; Rolf Tryselius; Sigurd Vitols; Christer von Bahr
The 'wise list'- a comprehensive concept to select, communicate and achieve adherence to recommendations of essential drugs in ambulatory care in Stockholm.
Basic & clinical pharmacology & toxicology 2011;108(4):224-33.
2011: Winifred Adrine Tumwikirize; Jasper W Ogwal-Okeng; Åsa Vernby; Willy Washington Anokbonggo; Lars ´Gustafsson; S C Lundborg
Adverse drug reactions in patients admitted on internal medicine wards in a district and regional hospital in Uganda.
African health sciences 2011;11(1):72-8.
2010: Rajaa A Mirghani; Ishraga Elagib; Gehad Elghazali; Urban Hellgren; Lars ´Gustafsson
Effects of Plasmodium falciparum infection on the pharmacokinetics of quinine and its metabolites in pregnant and non-pregnant Sudanese women.
European journal of clinical pharmacology 2010;66(12):1229-34.
2010: Jackson K Mukonzo; paul waako; Jasper Ogwal-Okeng; Lars ´Gustafsson; Eleni Aklillu
Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans.
Therapeutic drug monitoring 2010;32(3):346-52.
2010: Björn Wettermark; Marie E Persson; Nils Wilking; Mats Kalin; Seher Korkmaz; Paul Hjemdahl; Brian Godman; Max Petzold; Lars ´Gustafsson
Forecasting drug utilization and expenditure in a metropolitan health region.
BMC health services research 2010;10():128.
2009: Jackson K Mukonzo; Daniel Röshammar; paul waako; Maria Andersson; Takashi Fukasawa; Lili Milani; Jan-Olof Svensson; Jasper Ogwal-Okeng; Lars ´Gustafsson; Eleni Aklillu
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans.
British journal of clinical pharmacology 2009;68(5):690-9.
2009: Ylva Böttiger; Kari Laine; Marine L Andersson; Tuomas Korhonen; Björn Molin; Marie-Louise Ovesjö; Tuire Tirkkonen; Anders Rane; Lars ´Gustafsson; Birgit Eiermann
SFINX-a drug-drug interaction database designed for clinical decision support systems.
European journal of clinical pharmacology 2009;65(6):627-33.
2009: Suvi Ruuskanen; Blandine Doligez; Barbara Tschirren; Natalia Pitala; Lars ´Gustafsson; Ton G G Groothuis; Toni Laaksonen
Yolk androgens do not appear to mediate sexual conflict over parental investment in the collared flycatcher Ficedula albicollis.
Hormones and behavior 2009;55(4):514-9.
2009: Muhammad Ntale; Celestino Obua; Jackson Mukonzo; Margarita Mahindi; Lars ´Gustafsson; Olof Beck; Jasper W Ogwal-Okeng
Field-adapted sampling of whole blood to determine the levels of amodiaquine and its metabolite in children with uncomplicated malaria treated with amodiaquine plus artesunate combination.
Malaria journal 2009;8():52.
2008: M Ntale; Jasper W Ogwal-Okeng; Margarita Mahindi; Lars ´Gustafsson; Olof Beck
A field-adapted sampling and HPLC quantification method for lumefantrine and its desbutyl metabolite in whole blood spotted on filter paper.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;876(2):261-5.
2008: Winifred A Tumwikirize; Jasper W Ogwal-Okeng; Osa Vernby; Willy Washington Anokbonggo; Lars ´Gustafsson; Cecilia S Lundborg
Access and use of medicines information sources by physicians in public hospitals in Uganda: a cross-sectional survey.
African health sciences 2008;8(4):220-6.
2008: Celestino Obua; Urban Hellgren; Muhammed Ntale; Lars ´Gustafsson; Jasper W Ogwal-Okeng; Toufigh Gordi; Markus Jerling
Population pharmacokinetics of chloroquine and sulfadoxine and treatment response in children with malaria: suggestions for an improved dose regimen.
British journal of clinical pharmacology 2008;65(4):493-501.
2008: K Pfeiffer; F Some; Olaf Müller; A Sie; Bocar Kouyaté; Walter E Haefeli; A Zoungrana; Lars ´Gustafsson; G Tomson; Rainer Sauerborn
Clinical diagnosis of malaria and the risk of chloroquine self-medication in rural health centres in Burkina Faso.
Tropical medicine & international health : TM & IH 2008;13(3):418-26.
2008: Ulf Diczfalusy; Jun Miura; Hyung-Keun Roh; Rajaa A Mirghani; Jane Sayi; Hanna Larsson; Karl G Bodin; Annika Allqvist; Mary Jande; Jong-Wook Kim; Eleni Aklillu; Lars ´Gustafsson; Leif Bertilsson
4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians.
Pharmacogenetics and genomics 2008;18(3):201-8.
2008: Jaran Eriksen; S Mwankusye; S Mduma; Maria Veiga; Andrew Y Kitua; Göran Tomson; Max Petzold; Göte Swedberg; Lars ´Gustafsson; Marian Warsame
Antimalarial resistance and DHFR/DHPS genotypes of Plasmodium falciparum three years after introduction of sulfadoxine-pyrimethamine and amodiaquine in rural Tanzania.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2008;102(2):137-42.
2008: Billy Ngasala; Marycelina Mubi; Marian Warsame; Max Petzold; Amos Y Massele; Lars ´Gustafsson; Göran Tomson; Zul Premji; Anders Bjorkman
Impact of training in clinical and microscopy diagnosis of childhood malaria on antimalarial drug prescription and health outcome at primary health care level in Tanzania: a randomized controlled trial.
Malaria journal 2008;7():199.
2008: Björn Wettermark; Brian Godman; Karolina Andersson; Lars ´Gustafsson; Alan Haycox; Vittorio Bertele
Recent national and regional drug reforms in Sweden: implications for pharmaceutical companies in Europe.
PharmacoEconomics 2008;26(7):537-50.
2008: Bocar Kouyaté; Florent Somé; Albrecht Jahn; Boubacar Coulibaly; Jaran Eriksen; Rainer Sauerborn; Lars ´Gustafsson; Göran Tomson; Heiko Becher; Olaf Mueller
Process and effects of a community intervention on malaria in rural Burkina Faso: randomized controlled trial.
Malaria journal 2008;7():50.
2007: M Ntale; Margarita Mahindi; Jasper W Ogwal-Okeng; Lars ´Gustafsson; O Beck
A field-adapted HPLC method for determination of amodiaquine and its metabolite in whole blood dried on filter paper.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;859(1):137-40.
2007: Winifred Adrine Tumwikirize; Jasper W Ogwal-Okeng; Åsa Vernby; Willy Washington Anokbonggo; Lars ´Gustafsson; Cecilia Stålsby Lundborg
Access to up-to-date drug information in developing countries continues to pose problems: the case of Uganda.
Pharmacoepidemiology and drug safety 2007;16(10):1177-9.
2007: Bengt Sjöborg; Tobias Bäckström; Lars-Bertil Arvidsson; Eva Andersén-Karlsson; L Bengt Blomberg; Birgit Eiermann; Marie Eliasson; Kjell Henriksson; Lennart Jacobsson; Ulf Jacobsson; Margaretha Julander; Per-Olof Kaiser; Carina Landberg; Jonas Larsson; Björn Molin; Lars ´Gustafsson
Design and implementation of a point-of-care computerized system for drug therapy in Stockholm metropolitan health region--Bridging the gap between knowledge and practice.
International journal of medical informatics 2007;76(7):497-506.
2007: O M S Minzi; A Gupta; A F Haule; G A B Kagashe; Amosy Massele; Lars ´Gustafsson
Lack of impact of artesunate on the disposition kinetics of sulfadoxine/pyrimethamine when the two drugs are concomitantly administered.
European journal of clinical pharmacology 2007;63(5):457-62.
2007: F Josephson; Annika Allqvist; M Janabi; Jane Sayi; Eleni Aklillu; Mary Jande; Margarita Mahindi; J Burhenne; Y Bottiger; Lars ´Gustafsson; Walter E Haefeli; Leif Bertilsson
CYP3A5 genotype has an impact on the metabolism of the HIV protease inhibitor saquinavir.
Clinical pharmacology and therapeutics 2007;81(5):708-12.
2007: I I Abdelrahim; Ishag Adam; Gehad Elghazali; Lars ´Gustafsson; Mustafa I Elbashir; Rajaa A Mirghani
Pharmacokinetics of quinine and its metabolites in pregnant Sudanese women with uncomplicated Plasmodium falciparum malaria.
Journal of clinical pharmacy and therapeutics 2007;32(1):15-9.
2007: Jaran Eriksen; Göran Tomson; Phare Mujinja; Marian Warsame; Albrecht Jahn; Lars ´Gustafsson
Assessing health worker performance in malaria case management of underfives at health facilities in a rural Tanzanian district.
Tropical medicine & international health : TM & IH 2007;12(1):52-61.
2006: Celestino Obua; Lars ´Gustafsson; C Aguttu; Willy Washington Anokbonggo; Jasper W Ogwal-Okeng; J Chiria; Urban Hellgren
Improved efficacy with amodiaquine instead of chloroquine in sulfadoxine/pyrimethamine combination treatment of falciparum malaria in Uganda: experience with fixed-dose formulation.
Acta tropica 2006;100(1-2):142-50.
2006: Rajaa A Mirghani; Jane Sayi; Eleni Aklillu; Annika Allqvist; Mary Jande; Agneta Wennerholm; Jaran Eriksen; Virginie M M Herben; Barry C Jones; Lars ´Gustafsson; Leif Bertilsson
CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population.
Pharmacogenetics and genomics 2006;16(9):637-45.
2006: Agneta Wennerholm; Anna Nordmark; Maria Pihlsgård; Margarita Mahindi; Leif Bertilsson; Lars ´Gustafsson
Amodiaquine, its desethylated metabolite, or both, inhibit the metabolism of debrisoquine (CYP2D6) and losartan (CYP2C9) in vivo.
European journal of clinical pharmacology 2006;62(7):539-46.
2006: Celestino Obua; M Ntale; M S Lundblad; Margarita Mahindi; Lars ´Gustafsson; Jasper W Ogwal-Okeng; Willy Washington Anokbonggo; Urban Hellgren
Pharmacokinetic interactions between chloroquine, sulfadoxine and pyrimethamine and their bioequivalence in a generic fixed-dose combination in healthy volunteers in Uganda.
African health sciences 2006;6(2):86-92.
2006: O M S Minzi; Amosy Massele; Mary Justin-Temu; Orjan Ericsson; Lars ´Gustafsson
Existence of antimalarial formulations with low bioavailability in Tanzania.
Tropical doctor 2006;36(2):93-7.
2006: Marie Eliasson; Pia Bastholm; Peter Forsberg; Kjell Henriksson; Lennart Jacobson; Anders Nilsson; Lars ´Gustafsson
Janus computerised prescribing system provides pharmacological knowledge at point of care - design, development and proof of concept.
European journal of clinical pharmacology 2006;62(4):251-8.
2005: Cristina Rodríguez-Antona; Jane Sayi; Lars ´Gustafsson; Leif Bertilsson; Magnus Ingelman-Sundberg
Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles.
Biochemical and biophysical research communications 2005;338(1):299-305.
2005: Sargo Aalto; Jouni A Ihalainen; Jussi Hirvonen; Jaana Kajander; Harry Scheinin; Heikki Tanila; Kjell Någren; Harry Vilkman; Lars ´Gustafsson; Erkka Syvälahti; Jarmo Hietala
Cortical glutamate-dopamine interaction and ketamine-induced psychotic symptoms in man.
Psychopharmacology 2005;182(3):375-83.
2005: Jaran Eriksen; Stephen E D Nsimba; O M S Minzi; Anku J Sanga; Max Petzold; Lars ´Gustafsson; Marian Warsame; Göran Tomson
Adoption of the new antimalarial drug policy in Tanzania--a cross-sectional study in the community.
Tropical medicine & international health : TM & IH 2005;10(10):1038-46.
2005: Björn Wettermark; Kjell Haglund; Lars ´Gustafsson; Peter M Persson; Ulf Bergman
A study of adherence to drug recommendations by providing feedback of outpatient prescribing patterns to hospital specialists.
Pharmacoepidemiology and drug safety 2005;14(8):579-88.
2005: Agneta Wennerholm; Annika Allqvist; Jan-Olof Svensson; Lars ´Gustafsson; Rajaa A Mirghani; Leif Bertilsson
Alprazolam as a probe for CYP3A using a single blood sample: pharmacokinetics of parent drug, and of alpha- and 4-hydroxy metabolites in healthy subjects.
European journal of clinical pharmacology 2005;61(2):113-8.
2005: O M S Minzi; Amosy Massele; Lars ´Gustafsson; Orjan Ericsson
Simple and cost-effective liquid chromatographic method for determination of pyrimethamine in whole blood samples dried on filter paper.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;814(1):179-83.
2004: Jaran Eriksen; S Mwankusye; S Mduma; Andrew Y Kitua; G Swedberg; Göran Tomson; Lars ´Gustafsson; Marian Warsame
Patterns of resistance and DHFR/DHPS genotypes of Plasmodium falciparum in rural Tanzania prior to the adoption of sulfadoxine-pyrimethamine as first-line treatment.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2004;98(6):347-53.
2004: Lars ´Gustafsson
[Choice of antihypertensive agent--insignificant role of doxazosin (Alfadil). How are evidence-based recommendations implemented?].
Läkartidningen 2004;101(3):228-9.
2004: P Bastholm Rahmner; Eva Andersén-Karlsson; T Arnhjort; Marie Eliasson; Lars ´Gustafsson; L Jacobsson; M L Ovesjö; urban rosenqvist; S Sjöviker; G Tomson; Inger Holmström
Physicians' perceptions of possibilities and obstacles prior to implementing a computerised drug prescribing support system.
International journal of health care quality assurance incorporating Leadership in health services 2004;17(4-5):173-9.
2003: Karin Herrlin; Norio Yasui-Furukori; Gunnel Tybring; Jolanta Widén; Lars ´Gustafsson; Leif Bertilsson
Metabolism of citalopram enantiomers in CYP2C19/CYP2D6 phenotyped panels of healthy Swedes.
British journal of clinical pharmacology 2003;56(4):415-21.
2003: Asa Jansson; Lars ´Gustafsson; Rajaa A Mirghani
High-performance liquid chromatographic method for the determination of quinine and 3-hydroxyquinine in blood samples dried on filter paper.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;795(1):151-6.
2003: Rajaa A Mirghani; Urban Hellgren; Leif Bertilsson; Lars ´Gustafsson; Orjan Ericsson
Metabolism and elimination of quinine in healthy volunteers.
European journal of clinical pharmacology 2003;59(5-6):423-7.
2003: Xue-Qing Li; Anders Björkman; Tommy B Andersson; Lars ´Gustafsson; Collen M Masimirembwa
Identification of human cytochrome P(450)s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data.
European journal of clinical pharmacology 2003;59(5-6):429-42.
2003: Karin Hellman; Ewa Roos; Anna Osterlund; Anneli Wahlberg; Lars ´Gustafsson; Leif Bertilsson; Sten Fredrikson
Interferon-beta treatment in patients with multiple sclerosis does not alter CYP2C19 or CYP2D6 activity.
British journal of clinical pharmacology 2003;56(3):337-40.
2003: Rajaa A Mirghani; Orjan Ericsson; Gunnel Tybring; Lars ´Gustafsson; Leif Bertilsson
Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man.
European journal of clinical pharmacology 2003;59(1):23-8.
2003: Lars ´Gustafsson; Kenneth Widäng; Mikael Hoffmann; Eva Andersén-Karlsson; Karin Elfman; Björn Johansson; Eva Johansson; Mats Larson
[Computerized decision support in drug prescribing II: A national database to provide up-to-date and unbiased information].
Läkartidningen 2003;100(15):1338-40, 1343-4.
2003: Lars ´Gustafsson; Kenneth Widäng; Mikael Hoffmann; Eva Andersén-Karlsson; Karin Elfman; Björn Johansson; Eva Johansson; Mats Larson
[Computerized decision support in drug prescribing I: Better survey of patients' medications yields better quality of care].
Läkartidningen 2003;100(15):1333-7.
2003: O M S Minzi; MJ Moshi; D Hipolite; Amosy Massele; Göran Tomson; Orjan Ericsson; Lars ´Gustafsson
Evaluation of the quality of amodiaquine and sulphadoxine/pyrimethamine tablets sold by private wholesale pharmacies in Dar Es Salaam Tanzania.
Journal of clinical pharmacy and therapeutics 2003;28(2):117-22.
2003: O M S Minzi; M Rais; Jan-Olof Svensson; Lars ´Gustafsson; Orjan Ericsson
High-performance liquid chromatographic method for determination of amodiaquine, chloroquine and their monodesethyl metabolites in biological samples.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;783(2):473-80.
2003: Eva Arlander; Jan Sjövall; Jörgen Sörstad; Carina Norsten-Höög; Lars ´Gustafsson
Rectal ropivacaine is absorbed proportionally to the dose, with low intraindividual variability.
British journal of clinical pharmacology 2003;55(1):14-22.
2002: Sargo Aalto; Jussi Hirvonen; Jaana Kajander; Harry Scheinin; Kjell Någren; Harry Vilkman; Lars ´Gustafsson; Erkka Syvälahti; Jarmo Hietala
Ketamine does not decrease striatal dopamine D2 receptor binding in man.
Psychopharmacology 2002;164(4):401-6.
2002: Rajaa A Mirghani; Umit Yasar; Tao Zheng; James M Cook; Lars ´Gustafsson; Gunnel Tybring; Orjan Ericsson
Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro; 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(12):1368-71.
2002: Eleni Aklillu; Karin Herrlin; Lars ´Gustafsson; Leif Bertilsson; Magnus Ingelman-Sundberg
Evidence for environmental influence on CYP2D6-catalysed debrisoquine hydroxylation as demonstrated by phenotyping and genotyping of Ethiopians living in Ethiopia or in Sweden.
Pharmacogenetics 2002;12(5):375-83.
2002: Stephen E D Nsimba; Amosy Massele; Jaran Eriksen; Lars ´Gustafsson; Göran Tomson; Marian Warsame
Case management of malaria in under-fives at primary health care facilities in a Tanzanian district.
Tropical medicine & international health : TM & IH 2002;7(3):201-9.
2002: J Persson; Jan Hasselström; A Maurset; I Oye; Jan-Olof Svensson; O Almqvist; H Scheinin; Lars ´Gustafsson; O Almqvist
Pharmacokinetics and non-analgesic effects of S- and R-ketamines in healthy volunteers with normal and reduced metabolic capacity.
European journal of clinical pharmacology 2002;57(12):869-75.
2002: Agneta Wennerholm; Collet Dandara; Jane Sayi; Jan-Olof Svensson; Yakoub Aden Abdi; Magnus Ingelman-Sundberg; Leif Bertilsson; Julia A Hasler; Lars ´Gustafsson
The African-specific CYP2D617 allele encodes an enzyme with changed substrate specificity.
Clinical pharmacology and therapeutics 2002;71(1):77-88.
2001: Agneta Wennerholm; Inger Johansson; Mats Hidestrand; Leif Bertilsson; Lars ´Gustafsson; Magnus Ingelman-Sundberg
Characterization of the CYP2D6*29 allele commonly present in a black Tanzanian population causing reduced catalytic activity.
Pharmacogenetics 2001;11(5):417-27.
2001: Rajaa A Mirghani; Orjan Ericsson; J Cook; P Yu; Lars ´Gustafsson
Simultaneous determination of quinine and four metabolites in plasma and urine by high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 2001;754(1):57-64.
2001: Stephen E D Nsimba; Y Aden Abdi; GH Rimoy; Amosy Massele; C Alm; Orjan Ericsson; Lars ´Gustafsson
Comparative in vitro and in vivo study of a sugar-coated chloroquine preparation marketed in Tanzania versus an ordinary brand.
Journal of clinical pharmacy and therapeutics 2001;26(1):43-8.
2000: Karin Herrlin; M Segerdahl; Lars ´Gustafsson; E Kalso
Methadone, ciprofloxacin, and adverse drug reactions.
Lancet 2000;356(9247):2069-70.
2000: Lars ´Gustafsson; L O Hensjö
[Reply 1: LAKSAK supports wise drug therapy using knowledge and sharp IT-tools].
Läkartidningen 2000;97(39):4347.
2000: Erik Berninger; Lars ´Gustafsson
Changes in 2f1 - f2 acoustic distortion products in humans during quinine-induced cochlear dysfunction.
Acta oto-laryngologica 2000;120(5):600-6.
2000: Karin Herrlin; Amosy Massele; GH Rimoy; C Alm; M Rais; Orjan Ericsson; Leif Bertilsson; Lars ´Gustafsson
Slow chloroguanide metabolism in Tanzanians compared with white subjects and Asian subjects confirms a decreased CYP2C19 activity in relation to genotype.
Clinical pharmacology and therapeutics 2000;68(2):189-98.
2000: E Reihnér; R Grunditz; K Giesecke; Lars ´Gustafsson
Postoperative nausea and vomiting after breast surgery: efficacy of prophylactic ondansetron and droperidol in a randomized placebo-controlled study.
European journal of anaesthesiology 2000;17(3):197-203.
1999: Agneta Wennerholm; Inger Johansson; Amosy Massele; M Lande; C Alm; Y Aden Abdi; Marja-Liisa Dahl; Magnus Ingelman-Sundberg; Leif Bertilsson; Lars ´Gustafsson
Decreased capacity for debrisoquine metabolism among black Tanzanians: analyses of the CYP2D6 genotype and phenotype.
Pharmacogenetics 1999;9(6):707-14.
1999: Rajaa A Mirghani; Urban Hellgren; P A Westerberg; Orjan Ericsson; Leif Bertilsson; Lars ´Gustafsson
The roles of cytochrome P450 3A4 and 1A2 in the 3-hydroxylation of quinine in vivo.
Clinical pharmacology and therapeutics 1999;66(5):454-60.
1999: N Brynne; C Forslund; Bengt Hallén; Lars ´Gustafsson; Leif Bertilsson
Ketoconazole inhibits the metabolism of tolterodine in subjects with deficient CYP2D6 activity.
British journal of clinical pharmacology 1999;48(4):564-72.
1999: J Persson; H Scheinin; G Hellström; S Björkman; E Götharson; Lars ´Gustafsson
Ketamine antagonises alfentanil-induced hypoventilation in healthy male volunteers.
Acta anaesthesiologica Scandinavica 1999;43(7):744-52.
1998: Ulf Bronner; R Brun; Félix Doua; Orjan Ericsson; Christian Burri; Jennifer Keiser; T W Miézan; Y F Boa; Lars Rombo; Lars ´Gustafsson
Discrepancy in plasma melarsoprol concentrations between HPLC and bioassay methods in patients with T. gambiense sleeping sickness indicates that melarsoprol is metabolized.
Tropical medicine & international health : TM & IH 1998;3(11):913-7.
1998: E Arlander; G Ekström; C Alm; Juan Antonio Carrillo; M Bielenstein; Ylva Böttiger; Leif Bertilsson; Lars ´Gustafsson
Metabolism of ropivacaine in humans is mediated by CYP1A2 and to a minor extent by CYP3A4: an interaction study with fluvoxamine and ketoconazole as in vivo inhibitors.
Clinical pharmacology and therapeutics 1998;64(5):484-91.
1998: Karin Herrlin; Amosy Massele; Mary Jande; C Alm; Gunnel Tybring; Y A Abdi; Agneta Wennerholm; Inger Johansson; Marja-Liisa Dahl; Leif Bertilsson; Lars ´Gustafsson
Bantu Tanzanians have a decreased capacity to metabolize omeprazole and mephenytoin in relation to their CYP2C19 genotype.
Clinical pharmacology and therapeutics 1998;64(4):391-401.
1998: J Persson; Jan Hasselström; B Wiklund; A Heller; Jan-Olof Svensson; Lars ´Gustafsson
The analgesic effect of racemic ketamine in patients with chronic ischemic pain due to lower extremity arteriosclerosis obliterans.
Acta anaesthesiologica Scandinavica 1998;42(7):750-8.
1998: Lars ´Gustafsson; B Schildt; K Jacobsen
Adverse effects of extradural and intrathecal opiates: report of a nationwide survey in Sweden. 1982.
British journal of anaesthesia 1998;81(1):86-93; discussion 85.
1998: S Arnér; Lars ´Gustafsson; Per Hansson; E Kinnman; Alf Sollevi; J Sörensen
[Pharmacological pain analysis as diagnostic and therapeutic help].
Läkartidningen 1998;95(24):2824-8.
1998: Rajaa A Mirghani; Orjan Ericsson; Lars ´Gustafsson
High-performance liquid chromatographic method for the determination of the major quinine metabolite, 3-hydroxyquinine, in plasma and urine.
Journal of chromatography. B, Biomedical sciences and applications 1998;708(1-2):209-16.
1997: B M Emanuelsson; J Persson; C Alm; A Heller; Lars ´Gustafsson
Systemic absorption and block after epidural injection of ropivacaine in healthy volunteers.
Anesthesiology 1997;87(6):1309-17.
1997: J Nordin; I Wikström; Ulf Bronner; Lars ´Gustafsson; Orjan Ericsson
Liquid chromatography-tandem mass spectrometry applied to a study of the metabolism of pentamidine. Discussion of possibilities and problems.
Journal of chromatography. A 1997;777(1):73-9.
1997: M Eriksson-Mjöberg; Marianne Kristiansson; Kjell Carlström; Jan Eklund; Lars ´Gustafsson; A Olund
Preoperative infiltration of bupivacaine--effects on pain relief and trauma response (cortisol and interleukin-6).
Acta anaesthesiologica Scandinavica 1997;41(4):466-72.
1997: B M Emanuelsson; J Persson; S Sandin; C Alm; Lars ´Gustafsson
Intraindividual and interindividual variability in the disposition of the local anesthetic ropivacaine in healthy subjects.
Therapeutic drug monitoring 1997;19(2):126-31.
1997: Orjan Ericsson; Elke Schweda; Ulf Bronner; Lars Rombo; M Fridén; Lars ´Gustafsson
Determination of melarsoprol in biological fluids by high-performance liquid chromatography and characterisation of two stereoisomers by nuclear magnetic resonance spectroscopy.
Journal of chromatography. B, Biomedical sciences and applications 1997;690(1-2):243-51.
1997: Amosy Massele; C Kilewo; Y Aden Abdi; Göran Tomson; V K Diwan; Orjan Ericsson; GH Rimoy; Lars ´Gustafsson
Chloroquine blood concentrations and malaria prophylaxis in Tanzanian women during the second and third trimesters of pregnancy.
European journal of clinical pharmacology 1997;52(4):299-305.
1997: Cecilia Stålsby Lundborg; L O Hensjö; Lars ´Gustafsson
"Academic drug-detailing": from project to practice in a Swedish urban area.
European journal of clinical pharmacology 1997;52(3):167-72.
1997: M Eriksson-Mjöberg; Jan-Olof Svensson; O Almkvist; A Olund; Lars ´Gustafsson
Extradural morphine gives better pain relief than patient-controlled i.v. morphine after hysterectomy.
British journal of anaesthesia 1997;78(1):10-6.
1996: Lars ´Gustafsson; L S Eriksson; M L Dahl; L Eleborg; Bo-Göran Ericzon; A Nyberg
Cyclophosphamide-induced acute liver failure requiring transplantation in a patient with genetically deficient debrisoquine metabolism: a causal relationship?
Journal of internal medicine 1996;240(5):311-4.
1996: U Bergman; Lars ´Gustafsson; U Rydberg
[A new form for every fifth prescription!].
Läkartidningen 1996;93(20):1928-30.
1996: J O Svensson; Lars ´Gustafsson
Determination of ketamine and norketamine enantiomers in plasma by solid-phase extraction and high-performance liquid chromatography.
Journal of chromatography. B, Biomedical applications 1996;678(2):373-6.
1996: Collen M Masimirembwa; Lars ´Gustafsson; Marja-Liisa Dahl; Y A Abdi; Julia A Hasler
Lack of effect of chloroquine on the debrisoquine (CYP2D6 and S-mephenytoin (CYP2C19) hydroxylation phenotypes.
British journal of clinical pharmacology 1996;41(4):344-6.
1996: Lars ´Gustafsson; W F Ebling; E Osaki; Donald R Stanski
Quantitation of depth of thiopental anesthesia in the rat.
Anesthesiology 1996;84(2):415-27.
1995: Ulf Bronner; Orjan Ericsson; J Nordin; I Wikström; Y A Abdi; James Edwin Hall; Richard R Tidwell; Lars ´Gustafsson
Metabolism is an important route of pentamidine elimination in the rat: disposition of 14C-pentamidine and identification of metabolites in urine using liquid chromatography-tandem mass spectrometry.
Pharmacology & toxicology 1995;77(2):114-20.
1995: Per Hartvig; Johann Valtysson; KJ Lindner; J Kristensen; Rolf Karlsten; Lars ´Gustafsson; J Persson; J O Svensson; I Oye; Gunnar Antoni
Central nervous system effects of subdissociative doses of (S)-ketamine are related to plasma and brain concentrations measured with positron emission tomography in healthy volunteers.
Clinical pharmacology and therapeutics 1995;58(2):165-73.
1995: Ulf Bronner; Lars ´Gustafsson; Félix Doua; Orjan Ericsson; T Miézan; M Rais; Lars Rombo
Pharmacokinetics and adverse reactions after a single dose of pentamidine in patients with Trypanosoma gambiense sleeping sickness.
British journal of clinical pharmacology 1995;39(3):289-95.
1995: J Persson; G Axelsson; R G Hallin; Lars ´Gustafsson
Beneficial effects of ketamine in a chronic pain state with allodynia, possibly due to central sensitization.
Pain 1995;60(2):217-22.
1995: Sven Björkman; J Akeson; M Helfer; A Fyge; Lars ´Gustafsson
Cerebral uptake of morphine in the pig calculated from arterio-venous plasma concentration gradients: an alternative to tissue microdialysis.
Life sciences 1995;57(25):2335-45.
1994: Christer Lidman; Ulf Bronner; Lars ´Gustafsson; Lars Rombo
Plasma pentamidine concentrations vary between individuals with Pneumocystis carinii pneumonia and the drug is actively secreted by the kidney.
The Journal of antimicrobial chemotherapy 1994;33(4):803-10.
1994: Gilles Paintaud; Gunnar Alván; Erik Berninger; Lars ´Gustafsson; E Idrizbegovic; Kjell K Karlsson; M Wakelkamp
The concentration-effect relationship of quinine-induced hearing impairment.
Clinical pharmacology and therapeutics 1994;55(3):317-23.
1994: H Glaumann; Ulf Bronner; Orjan Ericsson; Lars ´Gustafsson; Lars Rombo
Pentamidine accumulates in rat liver lysosomes and inhibits phospholipid degradation.
Pharmacology & toxicology 1994;74(1):17-22.
1994: P Donatelli; G Marchi; L Giuliani; Lars ´Gustafsson; Gian Maria Pacifici
Stereoselective inhibition by chloroquine of histamine N-methyltransferase in the human liver and brain.
European journal of clinical pharmacology 1994;47(4):345-9.
1993: Orjan Ericsson; M Fridén; Urban Hellgren; Lars ´Gustafsson
Reversed-phase high-performance liquid chromatography determination of quinine in plasma, whole blood, urine, and samples dried on filter paper.
Therapeutic drug monitoring 1993;15(4):334-7.
1993: Y Aden Abdi; T Villén; Lars ´Gustafsson; Orjan Ericsson; Folke Sjöqvist
Methodological commentary on the analysis of metrifonate and dichlorvos in biological samples.
Journal of chromatography 1993;612(2):336-7; discussion 338-9.
1992: Lars ´Gustafsson; W F Ebling; E Osaki; S Harapat; Donald R Stanski; Steven Shafer
Plasma concentration clamping in the rat using a computer-controlled infusion pump.
Pharmaceutical research 1992;9(6):800-7.
1991: J Höjer; S Baehrendtz; A Magnusson; Lars ´Gustafsson
A placebo-controlled trial of flumazenil given by continuous infusion in severe benzodiazepine overdosage.
Acta anaesthesiologica Scandinavica 1991;35(7):584-90.
1991: Ulf Bronner; Félix Doua; Orjan Ericsson; Lars ´Gustafsson; T W Miézan; M Rais; Lars Rombo
Pentamidine concentrations in plasma, whole blood and cerebrospinal fluid during treatment of Trypanosoma gambiense infection in Côte d'Ivoire.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1991;85(5):608-11.
1991: H Wallinder; Lars ´Gustafsson; K Angbäck; P Höglund; A Magnusson; L Arvanius
Assay of theophylline: in vivo and in vitro evaluation of dry chemistry and immunoassay versus high-performance liquid chromatography.
Therapeutic drug monitoring 1991;13(3):233-9.
1990: J Höjer; S Baehrendtz; G Matell; Lars ´Gustafsson
Diagnostic utility of flumazenil in coma with suspected poisoning: a double blind, randomised controlled study.
BMJ (Clinical research ed.) 1990;301(6764):1308-11.
1990: H O Malmlund; Lars ´Gustafsson; A Magnusson; H Wallinder
[A case of lethal theophylline poisoning. Slow-release preparation gave treacherous and late symptoms].
Läkartidningen 1990;87(34):2585-8.
1990: T Villén; Y A Abdi; Orjan Ericsson; Lars ´Gustafsson; Folke Sjöqvist
Determination of metrifonate and dichlorvos in whole blood using gas chromatography and gas chromatography-mass spectrometry.
Journal of chromatography 1990;529(2):309-17.
1990: Y Aden-Abdi; T Villén; Orjan Ericsson; Lars ´Gustafsson; M L Dahl-Puustinen
Metrifonate in healthy volunteers: interrelationship between pharmacokinetic properties, cholinesterase inhibition and side-effects.
Bulletin of the World Health Organization 1990;68(6):731-6.
1989: J Höjer; S Baehrendtz; Lars ´Gustafsson
Benzodiazepine poisoning: experience of 702 admissions to an intensive care unit during a 14-year period.
Journal of internal medicine 1989;226(2):117-22.
1989: Lars ´Gustafsson; A Berg; A Magnusson; H O Malmlund; B M Sandell; R Stig
Hexapropymate self-poisoning causes severe and long-lasting clinical symptoms.
Medical toxicology and adverse drug experience 1989;4(4):295-301.
1989: Lars ´Gustafsson; Per Hartvig; K Bergström; Hans Lundqvist; B S Lindberg; Bengt Långström; H Svärd; H Rane; A Tamsen
Distribution of 11C-labelled morphine and pethidine after spinal administration to Rhesus monkey.
Acta anaesthesiologica Scandinavica 1989;33(2):105-11.
1989: Y Aden Abdi; Lars ´Gustafsson
Field trial of the efficacy of a simplified and standard metrifonate treatments of Schistosoma haematobium.
European journal of clinical pharmacology 1989;37(4):371-4.
1989: Y Aden Abdi; Lars ´Gustafsson
Poor patient compliance reduces the efficacy of metrifonate treatment of Schistosoma haematobium in Somalia.
European journal of clinical pharmacology 1989;36(2):161-4.
1988: Lars ´Gustafsson; Z Wiesenfeld-Hallin
Spinal opioid analgesia. A critical update.
Drugs 1988;35(6):597-603.
1988: S Arnér; Narinder Rawal; Lars ´Gustafsson
Clinical experience of long-term treatment with epidural and intrathecal opioids--a nationwide survey.
Acta anaesthesiologica Scandinavica 1988;32(3):253-9.
1988: H Wallinder; Lars ´Gustafsson
Monitoring quinidine concentrations in serum: discrepancies in results by fluorometry and immunoassay.
Clinical chemistry 1988;34(3):600.
1987: Lars ´Gustafsson; B Lindström; A Grahnén; G Alván
Chloroquine excretion following malaria prophylaxis.
British journal of clinical pharmacology 1987;24(2):221-4.
1987: Narinder Rawal; S Arnér; Lars ´Gustafsson; Renée Allvin
Present state of extradural and intrathecal opioid analgesia in Sweden. A nationwide follow-up survey.
British journal of anaesthesia 1987;59(6):791-9.
1987: Per Hartvig; Lars ´Gustafsson; K Bergström; U Moström; U Pontén; B Lindberg; Hans Lundqvist
Positron emission tomography: an animal model of spinal distribution of drugs after intrathecal administration.
Upsala journal of medical sciences 1987;92(2):205-13.
1987: Y Aden-Abdi; Lars ´Gustafsson; S A Elmi
A simplified dosage schedule of metrifonate in the treatment of Schistosoma haematobium infection in Somalia.
European journal of clinical pharmacology 1987;32(5):437-41.
1986: M Grind; B Siwers; C Graffner; G Alván; Lars ´Gustafsson; J Helleday; J E Lindgren; S Ogenstad; H Selander
Pressor response of oral tyramine in healthy men given amiflamine and placebo.
Clinical pharmacology and therapeutics 1986;40(2):155-60.
1986: G Alván; C Graffner; M Grind; Lars ´Gustafsson; J E Lindgren; C Nordin; S Ross; H Selander; B Siwers
Tolerance and pilot pharmacokinetics of amiflamine after increasing single oral doses in healthy subjects.
Clinical pharmacology and therapeutics 1986;40(1):81-5.
1986: L Rombo; A Björkman; E Sego; B Lindström; O Ericsson; Lars ´Gustafsson
Evaluation of three qualitative tests for detection of chloroquine in urine--agreement with plasma concentrations determined with liquid chromatography.
Annals of tropical medicine and parasitology 1986;80(3):293-8.
1986: Lars ´Gustafsson; C Post
The degree of analgesia correlates to spinal morphine concentration after intrathecal administration in rats.
Acta pharmacologica et toxicologica 1986;58(4):243-8.
1986: G M Pacifici; Lars ´Gustafsson; J Säwe; A Rane
Metabolic interaction between morphine and various benzodiazepines.
Acta pharmacologica et toxicologica 1986;58(4):249-52.
1986: Lars ´Gustafsson; J Johannisson; M Garle
Extradural and parenteral pethidine as analgesia after total hip replacement: effects and kinetics. A controlled clinical study.
European journal of clinical pharmacology 1986;29(5):529-34.
1986: Julio Benitez; R Dahlqvist; Lars ´Gustafsson; A Magnusson; F Sjöqvist
Clinical pharmacological evaluation of an assay kit for intoxications with tricyclic antidepressants.
Therapeutic drug monitoring 1986;8(1):102-5.
1985: Lars ´Gustafsson; C Post; B Edvardsen; C H Ramsay
Distribution of morphine and meperidine after intrathecal administration in rat and mouse.
Anesthesiology 1985;63(5):483-9.
1985: L Rombo; A Björkman; E Sego; B Lindström; O Ericsson; Lars ´Gustafsson
Reliability of Dill-Glazko test.
Lancet 1985;1(8444):1509.
1985: L Bertilsson; A Aberg-Wistedt; Lars ´Gustafsson; C Nordin
Extremely rapid hydroxylation of debrisoquine: a case report with implication for treatment with nortriptyline and other tricyclic antidepressants.
Therapeutic drug monitoring 1985;7(4):478-80.
1985: L Rombo; O Ericsson; G Alván; B Lindström; Lars ´Gustafsson; F Sjöqvist
Chloroquine and desethylchloroquine in plasma, serum, and whole blood: problems in assay and handling of samples.
Therapeutic drug monitoring 1985;7(2):211-5.
1984: Lars ´Gustafsson; A M Grell; M Garle; A Rane; B Schildt
Kinetics of morphine in cerebrospinal fluid after epidural administration.
Acta anaesthesiologica Scandinavica 1984;28(5):535-9.
1984: C J Dalsgaard; S R Vincent; T Hökfelt; Z Wiesenfeld-Hallin; Lars ´Gustafsson; R Elde; G J Dockray
Effects of cysteamine on pain behaviour and on somatostatin- and substance P-like immunoreactivity in the substantia gelatinosa of the rat.
European journal of pharmacology 1984;104(3-4):295-301.
1983: Lars ´Gustafsson; L Rombo; G Alván; A Björkman; M Lind; O Walker
On the question of dose-dependent chloroquine elimination of a single oral dose.
Clinical pharmacology and therapeutics 1983;34(3):383-5.
1983: Lars ´Gustafsson; O Walker; G Alván; B Beermann; F Estevez; L Gleisner; B Lindström; F Sjöqvist
Disposition of chloroquine in man after single intravenous and oral doses.
British journal of clinical pharmacology 1983;15(4):471-9.
1983: O Walker; D J Birkett; G Alván; Lars ´Gustafsson; F Sjöqvist
Characterization of chloroquine plasma protein binding in man.
British journal of clinical pharmacology 1983;15(3):375-7.
1983: Lars ´Gustafsson; Yngve Bergqvist; Orjan Ericsson; M Larsson; Lars Rombo
Pitfalls in the measurement of chloroquine concentration.
Lancet 1983;1(8316):126.
1982: Lars ´Gustafsson; S Friberg-Nielsen; M Garle; A Mohall; A Rane; B Schildt; T Symreng
Extradural and parenteral morphine: kinetics and effects in postoperative pain. A controlled clinical study.
British journal of anaesthesia 1982;54(11):1167-74.
1982: Z Wiesenfeld; Lars ´Gustafsson
Continuous intrathecal administration of morphine via an osmotic minipump in the rat.
Brain research 1982;247(1):195-7.
1982: Lars ´Gustafsson; B Schildt; K Jacobsen
Adverse effects of extradural and intrathecal opiates: report of a nationwide survey in Sweden.
British journal of anaesthesia 1982;54(5):479-86.
1982: Lars ´Gustafsson; S Ackerman; H Adamson; M Garle; A Rane; B Schildt
Disposition of morphine in cerebrospinal fluid after epidural administration.
Lancet 1982;1(8275):796.
1982: A Skjöldebrand; M Garle; Lars ´Gustafsson; H Johansson; NO Lunell; A Rane
Extradural pethidine with and without adrenaline during labour: wide variation in effect.
British journal of anaesthesia 1982;54(4):415-20.
1982: Lars ´Gustafsson; G Boëthius
Utilization of analgesics from 1970 to 1978. Prescription patterns in the county of Jämtland and in Sweden as a whole.
Acta medica Scandinavica 1982;211(6):419-25.
1982: Lars ´Gustafsson; M Garle; J Johannisson; A Rane; J Stenport; P Walson
Regional epidural analgesia: kinetics of pethidine.
Acta anaesthesiologica Scandinavica. Supplementum 1982;74():165-8.
1981: G Alván; U Bergman; Lars ´Gustafsson
High unbound fraction of salicylate in plasma during intoxication.
British journal of clinical pharmacology 1981;11(6):625-6.
1981: Lars ´Gustafsson; A Notander
[Water intoxication associated with transurethral electroresection].
Läkartidningen 1981;78(22):2233.
1981: Lars ´Gustafsson; B Feychting; C Klingstedt
Late respiratory depression after concomitant use of morphine epidurally and parenterally.
Lancet 1981;1(8225):892-3.
1981: Lars ´Gustafsson; K Wide
Marketing of obsolete antibiotics in Central America.
Lancet 1981;1(8210):31-3.
1980: Lars ´Gustafsson
[Use of morphine analgesics in hospitals].
Läkartidningen 1980;77(47):4402-4.
1979: G Alván; Lars ´Gustafsson; B Ohman
[Adverse effects of cimetidine--the current situation].
Läkartidningen 1979;76(34):2767.
1975: Lars ´Gustafsson
[To become and to be a physician].
Läkartidningen 1975;72(36):3263-6.