Wolfgang F. Graier

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Slaven Crnkovic; Monika Riederer; Margarete Lechleitner; Seth Hallström; Roland Malli; Wolfgang F Graier; Jörg Lindenmann; Helmut Popper; Horst Olschewski; Andrea Olschewski; et al.
Docosahexaenoic acid-induced unfolded protein response, cell cycle arrest, and apoptosis in vascular smooth muscle cells are triggered by Ca(2+)-dependent induction of oxidative stress.
Claire Jean-Quartier; Alexander I Bondarenko; Muhammad Rizwan Alam; Michael Trenker; Markus Waldeck-Weiermair; Roland Malli; Wolfgang F Graier
Studying mitochondrial Ca(2+) uptake - a revisit.
Markus Waldeck-Weiermair; Claire Jean-Quartier; Rene Rost; Muhammad Jadoon Khan; Neelanjan Vishnu; Alexander I Bondarenko; Hiromi Imamura; Roland Malli; Wolfgang F Graier
Leucine zipper EF hand-containing transmembrane protein 1 (Letm1) and uncoupling proteins 2 and 3 (UCP2/3) contribute to two distinct mitochondrial Ca2+ uptake pathways.

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2012: Slaven Crnkovic; Monika Riederer; Margarete Lechleitner; Seth Hallström; Roland Malli; Wolfgang F Graier; Jörg Lindenmann; Helmut Popper; Horst Olschewski; Andrea Olschewski; et al.
Docosahexaenoic acid-induced unfolded protein response, cell cycle arrest, and apoptosis in vascular smooth muscle cells are triggered by Ca(2+)-dependent induction of oxidative stress.
Free radical biology & medicine 2012;52(9):1786-95.
2012: Claire Jean-Quartier; Alexander I Bondarenko; Muhammad Rizwan Alam; Michael Trenker; Markus Waldeck-Weiermair; Roland Malli; Wolfgang F Graier
Studying mitochondrial Ca(2+) uptake - a revisit.
Molecular and cellular endocrinology 2012;353(1-2):114-27.
2011: Markus Waldeck-Weiermair; Claire Jean-Quartier; Rene Rost; Muhammad Jadoon Khan; Neelanjan Vishnu; Alexander I Bondarenko; Hiromi Imamura; Roland Malli; Wolfgang F Graier
Leucine zipper EF hand-containing transmembrane protein 1 (Letm1) and uncoupling proteins 2 and 3 (UCP2/3) contribute to two distinct mitochondrial Ca2+ uptake pathways.
The Journal of biological chemistry 2011;286(32):28444-55.
2011: Alexander I Bondarenko; Roland Malli; Wolfgang F Graier
The GPR55 agonist lysophosphatidylinositol directly activates intermediate-conductance Ca2+ -activated K+ channels.
Pflügers Archiv : European journal of physiology 2011;462(2):245-55.
2011: Elma Aflaki; Branislav Radovic; Prakash G Chandak; Dagmar Kolb; Tobias Eisenberg; Julia Ring; Ismene Fertschai; Andreas Uellen; Heimo Wolinski; Sepp-Dieter Kohlwein; et al.
Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages.
The Journal of biological chemistry 2011;286(9):7418-28.
2011: Alexander I Bondarenko; Rolland Malli; Wolfgang F Graier
The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca2+ -activated large-conductance K+ channels in endothelial cells.
Pflügers Archiv : European journal of physiology 2011;461(1):177-89.
2010: Markus Waldeck-Weiermair; Xiumei Duan; Shamim Naghdi; Muhammad Jadoon Khan; Michael Trenker; Roland Malli; Wolfgang F Graier
Uncoupling protein 3 adjusts mitochondrial Ca(2+) uptake to high and low Ca(2+) signals.
Cell calcium 2010;48(5):288-301.
2010: Alexander Bondarenko; Markus Waldeck-Weiermair; Shamim Naghdi; Michael Poteser; Roland Malli; Wolfgang F Graier
GPR55-dependent and -independent ion signalling in response to lysophosphatidylinositol in endothelial cells.
British journal of pharmacology 2010;161(2):308-20.
2010: Shamim Naghdi; Markus Waldeck-Weiermair; Ismene Fertschai; Michael Poteser; Wolfgang F Graier; Roland Malli
Mitochondrial Ca2+ uptake and not mitochondrial motility is required for STIM1-Orai1-dependent store-operated Ca2+ entry.
Journal of cell science 2010;123(Pt 15):2553-64.
2010: Roland Malli; Wolfgang F Graier
Mitochondrial Ca2+ channels: Great unknowns with important functions.
FEBS letters 2010;584(10):1942-7.
2010: Markus Waldeck-Weiermair; Roland Malli; Shamim Naghdi; Michael Trenker; Muhammad Jadoon Kahn; Wolfgang F Graier
The contribution of UCP2 and UCP3 to mitochondrial Ca(2+) uptake is differentially determined by the source of supplied Ca(2+).
Cell calcium 2010;47(5):433-40.
2010: Eva Bernhart; Manfred Kollroser; Gerald Rechberger; Helga Reicher; Akos Heinemann; Petra Schratl; Seth Hallström; Andrea Wintersperger; Christoph Nusshold; Trevor DeVaney; et al.
Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture.
Proteomics 2010;10(1):141-58.
2009: Wolfgang F Graier; Roland Malli; Gerhard M Kostner
Mitochondrial protein phosphorylation: instigator or target of lipotoxicity?
Trends in endocrinology and metabolism: TEM 2009;20(4):186-93.
2008: Wolfgang F Graier; Markus Hecker
Endothelial H2O2: a bad guy turning good?
Arteriosclerosis, thrombosis, and vascular biology 2008;28(10):1691-3.
2008: Roland Malli; Shamim Naghdi; Christoph Romanin; Wolfgang F Graier
Cytosolic Ca2+ prevents the subplasmalemmal clustering of STIM1: an intrinsic mechanism to avoid Ca2+ overload.
Journal of cell science 2008;121(Pt 19):3133-9.
2008: Wolfgang F Graier; Michael Trenker; Roland Malli
Mitochondrial Ca2+, the secret behind the function of uncoupling proteins 2 and 3?
Cell calcium 2008;44(1):36-50.
2008: Martina Schweiger; Gabriele Schoiswohl; Achim Lass; Franz P W Radner; Guenter Haemmerle; Roland Malli; Wolfgang Graier; Irina Cornaciu; Monika Oberer; Robert Salvayre; et al.
The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding.
The Journal of biological chemistry 2008;283(25):17211-20.
2008: Markus Waldeck-Weiermair; Cristina Zoratti; Karin Osibow; Nariman Balenga; Edith Goessnitzer; Maria Waldhoer; Roland Malli; Wolfgang F Graier
Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression.
Journal of cell science 2008;121(Pt 10):1704-17.
2008: H Jousset; R Malli; N Girardin; W F Graier; N Demaurex; M Frieden
Evidence for a receptor-activated Ca2+ entry pathway independent from Ca2) store depletion in endothelial cells.
Cell calcium 2008;43(1):83-94.
2007: Wolfgang F Graier; Maud Frieden; Roland Malli
Mitochondria and Ca(2+) signaling: old guests, new functions.
Pflügers Archiv : European journal of physiology 2007;455(3):375-96.
2007: Michael Trenker; Roland Malli; Ismene Fertschai; Sanja Levak-Frank; Wolfgang F Graier
Uncoupling proteins 2 and 3 are fundamental for mitochondrial Ca2+ uniport.
Nature cell biology 2007;9(4):445-52.
2007: Gerlinde Wiesenberger; Katarina Steinleitner; Roland Malli; Wolfgang F Graier; Jürgen Vormann; Rudolf J Schweyen; Jochen A Stadler
Mg2+ deprivation elicits rapid Ca2+ uptake and activates Ca2+/calcineurin signaling in Saccharomyces cerevisiae.
Eukaryotic cell 2007;6(4):592-9.
2007: R Malli; M Frieden; M Hunkova; M Trenker; W F Graier
Ca2+ refilling of the endoplasmic reticulum is largely preserved albeit reduced Ca2+ entry in endothelial cells.
Cell calcium 2007;41(1):63-76.
2006: Karin Osibow; Sasa Frank; Roland Malli; Rudolf Zechner; Wolfgang F Graier
Mitochondria maintain maturation and secretion of lipoprotein lipase in the endoplasmic reticulum.
The Biochemical journal 2006;396(1):173-82.
2006: Karin Osibow; Roland Malli; Gerhard M Kostner; Wolfgang F Graier
A new type of non-Ca2+-buffering Apo(a)-based fluorescent indicator for intraluminal Ca2+ in the endoplasmic reticulum.
The Journal of biological chemistry 2006;281(8):5017-25.
2005: Dijle Kipmen-Korgun; Karin Osibow; Cristina Zoratti; Elisabeth Schraml; Joachim Greilberger; Gerhard M Kostner; Günther Jürgens; Wolfgang F Graier
T-cadherin mediates low-density lipoprotein-initiated cell proliferation via the Ca(2+)-tyrosine kinase-Erk1/2 pathway.
Journal of cardiovascular pharmacology 2005;45(5):418-30.
2005: Harm J Knot; Ismail Laher; Eric A Sobie; Silvia Guatimosim; Leticia Gomez-Viquez; Hali Hartmann; Long-Sheng Song; W J Lederer; Wolfgang F Graier; Roland Malli; et al.
Twenty years of calcium imaging: cell physiology to dye for.
Molecular interventions 2005;5(2):112-27.
2005: Rolland Malli; Maud Frieden; Michael Trenker; Wolfgang F Graier
The role of mitochondria for Ca2+ refilling of the endoplasmic reticulum.
The Journal of biological chemistry 2005;280(13):12114-22.
2004: Gunther Marsche; Regine Heller; Günter Fauler; Alenka Kovacevic; Alexander Nuszkowski; Wolfgang Graier; Wolfgang Sattler; Ernst Malle
2-chlorohexadecanal derived from hypochlorite-modified high-density lipoprotein-associated plasmalogen is a natural inhibitor of endothelial nitric oxide biosynthesis.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(12):2302-6.
2004: Annarita Graziani; Verena Bricko; Marco Carmignani; Wolfgang F Graier; Klaus Groschner
Cholesterol- and caveolin-rich membrane domains are essential for phospholipase A2-dependent EDHF formation.
Cardiovascular research 2004;64(2):234-42.
2004: Jolanta Paltauf-Doburzynska; Roland Malli; Wolfgang F Graier
Hyperglycemic conditions affect shape and Ca2+ homeostasis of mitochondria in endothelial cells.
Journal of cardiovascular pharmacology 2004;44(4):423-36.
2004: Martin Bilban; Nassim Ghaffari-Tabrizi; Edith Hintermann; Sandra Bauer; Sylvia Molzer; Cristina Zoratti; Roland Malli; Andrew Sharabi; Ursula Hiden; Wolfgang Graier; et al.
Kisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblasts.
Journal of cell science 2004;117(Pt 8):1319-28.
2003: Cristina Zoratti; Dijle Kipmen-Korgun; Karin Osibow; Roland Malli; Wolfgang F Graier
Anandamide initiates Ca(2+) signaling via CB2 receptor linked to phospholipase C in calf pulmonary endothelial cells.
British journal of pharmacology 2003;140(8):1351-62.
2003: Roland Malli; Maud Frieden; Karin Osibow; Cristina Zoratti; Mirza Mayer; Nicolas Demaurex; Wolfgang F Graier
Sustained Ca2+ transfer across mitochondria is Essential for mitochondrial Ca2+ buffering, sore-operated Ca2+ entry, and Ca2+ store refilling.
The Journal of biological chemistry 2003;278(45):44769-79.
2003: G Schaeffer; S Levak-Frank; M M Spitaler; E Fleischhacker; V E Esenabhalu; A H Wagner; M Hecker; W F Graier
Intercellular signalling within vascular cells under high D-glucose involves free radical-triggered tyrosine kinase activation.
Diabetologia 2003;46(6):773-83.
2003: Michaela Artwohl; Wolfgang F Graier; Michael Roden; Martin Bischof; Angelika Freudenthaler; Werner Waldhäusl; Sabina M Baumgartner-Parzer
Diabetic LDL triggers apoptosis in vascular endothelial cells.
Diabetes 2003;52(5):1240-7.
2003: Victor E Esenabhalu; Gabriela Schaeffer; Wolfgang F Graier
Free fatty acid overload attenuates Ca2+ signaling and NO production in endothelial cells.
Antioxidants & redox signaling 2003;5(2):147-53.
2003: Roland Malli; Maud Frieden; Karin Osibow; Wolfgang F Graier
Mitochondria efficiently buffer subplasmalemmal Ca2+ elevation during agonist stimulation.
The Journal of biological chemistry 2003;278(12):10807-15.
2002: Baskaran Thyagarajan; Roland Malli; Kurt Schmidt; Wolfgang F Graier; Klaus Groschner
Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling.
British journal of pharmacology 2002;137(6):821-30.
2002: Michaela M Spitaler; Astrid Hammer; Roland Malli; Wolfgang F Graier
Functional analysis of histamine receptor subtypes involved in endothelium-mediated relaxation of the human uterine artery.
Clinical and experimental pharmacology & physiology 2002;29(8):711-6.
2002: Andreas Tiran; Hans-Jürgen Gruber; Wolfgang F Graier; Andreas H Wagner; Ellen B M Van Leeuwen; Beate Tiran
Aspirin inhibits Chlamydia pneumoniae-induced nuclear factor-kappa B activation, cytokine expression, and bacterial development in human endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(7):1075-80.
2002: M M Spitaler; W F Graier
Vascular targets of redox signalling in diabetes mellitus.
Diabetologia 2002;45(4):476-94.
2002: Maud Frieden; Roland Malli; Mariana Samardzija; Nicolas Demaurex; Wolfgang F Graier
Subplasmalemmal endoplasmic reticulum controls K(Ca) channel activity upon stimulation with a moderate histamine concentration in a human umbilical vein endothelial cell line.
The Journal of physiology 2002;540(Pt 1):73-84.
2002: Victor E Esenabhalu; Mirza Cerimagic; Roland Malli; Karin Osibow; Sanja Levak-Frank; Maud Frieden; Wolfgang Sattler; Gerhard M Kostner; Rudolf Zechner; Wolfgang F Graier
Tissue-specific expression of human lipoprotein lipase in the vascular system affects vascular reactivity in transgenic mice.
British journal of pharmacology 2002;135(1):143-54.
2002: Valery N Bochkov; Diana Mechtcheriakova; Marcus Lucerna; Joakim Huber; Roland Malli; Wolfgang F Graier; Erhard Hofer; Bernd R Binder; Norbert Leitinger
Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT.
Blood 2002;99(1):199-206.
2001: D K Bowles; W F Graier; M Sturek
Hydrogen peroxide activates Na(+)-dependent Ca(2+) influx in coronary endothelial cells.
Biochemical and biophysical research communications 2001;287(5):1134-9.
2001: R Zimmermann; U Panzenböck; A Wintersperger; S Levak-Frank; W Graier; O Glatter; G Fritz; G M Kostner; R Zechner
Lipoprotein lipase mediates the uptake of glycated LDL in fibroblasts, endothelial cells, and macrophages.
Diabetes 2001;50(7):1643-53.
2001: V Schulter; P Koolwijk; E Peters; S Frank; A Hrzenjak; W F Graier; V W van Hinsbergh; G M Kostner
Impact of apolipoprotein(a) on in vitro angiogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(3):433-8.
2000: B Lintschinger; M Balzer-Geldsetzer; T Baskaran; W F Graier; C Romanin; M X Zhu; K Groschner
Coassembly of Trp1 and Trp3 proteins generates diacylglycerol- and Ca2+-sensitive cation channels.
The Journal of biological chemistry 2000;275(36):27799-805.
2000: S Prattes; G Hörl; A Hammer; A Blaschitz; W F Graier; W Sattler; R Zechner; E Steyrer
Intracellular distribution and mobilization of unesterified cholesterol in adipocytes: triglyceride droplets are surrounded by cholesterol-rich ER-like surface layer structures.
Journal of cell science 2000;113 ( Pt 17)():2977-89.
2000: M Frieden; W F Graier
Subplasmalemmal ryanodine-sensitive Ca2+ release contributes to Ca2+-dependent K+ channel activation in a human umbilical vein endothelial cell line.
The Journal of physiology 2000;524 Pt 3():715-24.
2000: J Paltauf-Doburzynska; M Frieden; M Spitaler; W F Graier
Histamine-induced Ca2+ oscillations in a human endothelial cell line depend on transmembrane ion flux, ryanodine receptors and endoplasmic reticulum Ca2+-ATPase.
The Journal of physiology 2000;524 Pt 3():701-13.
2000: E Fleischhacker; V E Esenabhalu; S Holzmann; F Skrabal; B Koidl; G M Kostner; W F Graier
In human hypercholesterolemia increased reactivity of vascular smooth muscle cells is due to altered subcellular Ca(2+) distribution.
Atherosclerosis 2000;149(1):33-42.
1999: W F Graier; K Posch; E Fleischhacker; T C Wascher; G M Kostner
Increased superoxide anion formation in endothelial cells during hyperglycemia: an adaptive response or initial step of vascular dysfunction?
Diabetes research and clinical practice 1999;45(2-3):153-60.
1999: K Posch; S Simecek; T C Wascher; G Jürgens; S Baumgartner-Parzer; G M Kostner; W F Graier
Glycated low-density lipoprotein attenuates shear stress-induced nitric oxide synthesis by inhibition of shear stress-activated L-arginine uptake in endothelial cells.
Diabetes 1999;48(6):1331-7.
1999: E Fleischhacker; V E Esenabhalu; M Spitaler; S Holzmann; F Skrabal; B Koidl; G M Kostner; W F Graier
Human diabetes is associated with hyperreactivity of vascular smooth muscle cells due to altered subcellular Ca2+ distribution.
Diabetes 1999;48(6):1323-30.
1999: J Paltauf-Doburzynska; M Frieden; W F Graier
Mechanisms of Ca2+ store depletion in single endothelial cells in a Ca(2+)-free environment.
Cell calcium 1999;25(5):345-53.
1999: J V Mombouli; S Holzmann; G M Kostner; W F Graier
Potentiation of Ca2+ signaling in endothelial cells by 11,12-epoxyeicosatrienoic acid.
Journal of cardiovascular pharmacology 1999;33(5):779-84.
1999: J V Mombouli; G Schaeffer; S Holzmann; G M Kostner; W F Graier
Anandamide-induced mobilization of cytosolic Ca2+ in endothelial cells.
British journal of pharmacology 1999;126(7):1593-600.
1999: G Schaeffer; T C Wascher; G M Kostner; W F Graier
Alterations in platelet Ca2+ signalling in diabetic patients is due to increased formation of superoxide anions and reduced nitric oxide production.
Diabetologia 1999;42(2):167-76.
1999: K Posch; K Schmidt; W F Graier
Selective stimulation of L-arginine uptake contributes to shear stress-induced formation of nitric oxide.
Life sciences 1999;64(8):663-70.
1998: J Paltauf-Doburzynska; K Posch; G Paltauf; W F Graier
Stealth ryanodine-sensitive Ca2+ release contributes to activity of capacitative Ca2+ entry and nitric oxide synthase in bovine endothelial cells.
The Journal of physiology 1998;513 ( Pt 2)():369-79.
1998: B G Hoebel; E Steyrer; W F Graier
Origin and function of epoxyeicosatrienoic acids in vascular endothelial cells: more than just endothelium-derived hyperpolarizing factor?
Clinical and experimental pharmacology & physiology 1998;25(10):826-30.
1998: W F Graier; B G Hoebel; J Paltauf-Doburzynska; G M Kostner
Effects of superoxide anions on endothelial Ca2+ signaling pathways.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(9):1470-9.
1998: B G Hoebel; W F Graier
11,12-Epoxyeicosatrienoic acid stimulates tyrosine kinase activity in porcine aortic endothelial cells.
European journal of pharmacology 1998;346(1):115-7.
1998: W F Graier; J Paltauf-Doburzynska; B J Hill; E Fleischhacker; B G Hoebel; G M Kostner; M Sturek
Submaximal stimulation of porcine endothelial cells causes focal Ca2+ elevation beneath the cell membrane.
The Journal of physiology 1998;506 ( Pt 1)():109-25.
1997: W F Graier; K Posch; T C Wascher; G M Kostner
Role of superoxide anions in changes of endothelial vasoactive response during acute hyperglycemia.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1997;29(12):622-6.
1997: B G Hoebel; G M Kostner; W F Graier
Activation of microsomal cytochrome P450 mono-oxygenase by Ca2+ store depletion and its contribution to Ca2+ entry in porcine aortic endothelial cells.
British journal of pharmacology 1997;121(8):1579-88.
1997: T C Wascher; W F Graier; P Dittrich; M A Hussain; B Bahadori; S Wallner; H Toplak
Effects of low-dose L-arginine on insulin-mediated vasodilatation and insulin sensitivity.
European journal of clinical investigation 1997;27(8):690-5.
1997: W F Graier; G M Kostner
Glycated low-density lipoprotein and atherogenesis: the missing link between diabetes mellitus and hypercholesterolaemia?
European journal of clinical investigation 1997;27(6):457-9.
1997: T C Wascher; K Posch; S Wallner; A Hermetter; G M Kostner; W F Graier
Vascular effects of L-arginine: anything beyond a substrate for the NO-synthase?
Biochemical and biophysical research communications 1997;234(1):35-8.
1997: W F Graier; S Simecek; B G Hoebel; T C Wascher; P Dittrich; G M Kostner
Antioxidants prevent high-D-glucose-enhanced endothelial Ca2+/cGMP response by scavenging superoxide anions.
European journal of pharmacology 1997;322(1):113-22.
1997: J Paltauf-Doburzynska; W F Graier
Temperature dependence of agonist-stimulated Ca2+ signaling in cultured endothelial cells.
Cell calcium 1997;21(1):43-51.
1996: W F Graier; S Holzmann; B G Hoebel; W R Kukovetz; G M Kostner
Mechanisms of L-NG nitroarginine/indomethacin-resistant relaxation in bovine and porcine coronary arteries.
British journal of pharmacology 1996;119(6):1177-86.
1996: W F Graier; S Simecek; W R Kukovetz; G M Kostner
High D-glucose-induced changes in endothelial Ca2+/EDRF signaling are due to generation of superoxide anions.
Diabetes 1996;45(10):1386-95.
1996: T C Wascher; M Bachernegg; A Kickenweiz; G Stark; U Stark; H Toplak; W F Graier
Involvement of the L-arginine-nitric oxide pathway in hyperglycaemia-induced coronary artery dysfunction of isolated guinea pig hearts.
European journal of clinical investigation 1996;26(8):707-12.
1996: G W He; C Q Yang; W F Graier; J A Yang
Hyperkalemia alters EDHF-mediated hyperpolarization and relaxation in coronary arteries.
The American journal of physiology 1996;271(2 Pt 2):H760-7.
1995: W F Graier; I Grubenthal; P Dittrich; T C Wascher; G M Kostner
Intracellular mechanism of high D-glucose-induced modulation of vascular cell proliferation.
European journal of pharmacology 1995;294(1):221-9.
1995: T C Wascher; M Bachernegg; E Kickenweiz; G Stark; U Stark; H Toplak; W F Graier; G J Krejs
Elevation of D-glucose impairs coronary artery autoregulation after slight reduction of coronary flow.
European journal of clinical investigation 1995;25(8):590-4.
1995: H Toplak; W Graier; P Dittrich; U N Wiesmann; T C Wascher
Insulin resistance and membrane abnormalities.
Lancet 1995;345(8955):995; author reply 995-6.
1995: W F Graier; S Simecek; M Sturek
Cytochrome P450 mono-oxygenase-regulated signalling of Ca2+ entry in human and bovine endothelial cells.
The Journal of physiology 1995;482 ( Pt 2)():259-74.
1995: F Brunner; H Stessel; W F Graier
The effects of intracellular Ca2+ concentration and hypoxia on basal endothelin-1 secretion by cultured porcine aortic endothelial cells.
Agents and actions. Supplements 1995;45():269-73.
1994: W F Graier; P R Myers; L J Rubin; H R Adams; J L Parker
Escherichia coli endotoxin inhibits agonist-mediated cytosolic Ca2+ mobilization and nitric oxide biosynthesis in cultured endothelial cells.
Circulation research 1994;75(4):659-68.
1994: T C Wascher; P Dittrich; H Toplak; W G Graier
Endothelial dysfunction in hypertension.
Lancet 1994;344(8921):549-50.
1994: F Brunner; H Stessel; S Simecek; W Graier; W R Kukovetz
Effect of intracellular Ca2+ concentration on endothelin-1 secretion.
FEBS letters 1994;350(1):33-6.
1994: T C Wascher; W F Graier; B Bahadori; H Toplak
Time course of endothelial dysfunction in diabetes mellitus.
Circulation 1994;90(2):1109-10.
1994: T C Wascher; H Toplak; G J Krejs; S Simecek; W R Kukovetz; W F Graier
Intracellular mechanisms involved in D-glucose-mediated amplification of agonist-induced Ca2+ response and EDRF formation in vascular endothelial cells.
Diabetes 1994;43(8):984-91.
1994: K Groschner; W F Graier; W R Kukovetz
Histamine induces K+, Ca2+, and Cl- currents in human vascular endothelial cells. Role of ionic currents in stimulation of nitric oxide biosynthesis.
Circulation research 1994;75(2):304-14.
1994: W F Graier; S Simecek; D K Bowles; M Sturek
Heterogeneity of caffeine- and bradykinin-sensitive Ca2+ stores in vascular endothelial cells.
The Biochemical journal 1994;300 ( Pt 3)():637-41.
1994: S Holzmann; W R Kukovetz; W Windischhofer; E Paschke; W F Graier
Pharmacologic differentiation between endothelium-dependent relaxations sensitive and resistant to nitro-L-arginine in coronary arteries.
Journal of cardiovascular pharmacology 1994;23(5):747-56.
1993: W F Graier; T C Wascher; L Lackner; H Toplak; G J Krejs; W R Kukovetz
Exposure to elevated D-glucose concentrations modulates vascular endothelial cell vasodilatory response.
Diabetes 1993;42(10):1497-505.
1993: W F Graier; W R Kukovetz; K Groschner
Cyclic AMP enhances agonist-induced Ca2+ entry into endothelial cells by activation of potassium channels and membrane hyperpolarization.
The Biochemical journal 1993;291 ( Pt 1)():263-7.
1992: W F Graier; K Groschner; K Schmidt; W R Kukovetz
Increases in endothelial cyclic AMP levels amplify agonist-induced formation of endothelium-derived relaxing factor (EDRF).
The Biochemical journal 1992;288 ( Pt 2)():345-9.
1992: K Groschner; W F Graier; W R Kukovetz
Activation of a small-conductance Ca(2+)-dependent K+ channel contributes to bradykinin-induced stimulation of nitric oxide synthesis in pig aortic endothelial cells.
Biochimica et biophysica acta 1992;1137(2):162-70.
1992: W F Graier; K Groschner; K Schmidt; W R Kukovetz
SK&F 96365 inhibits histamine-induced formation of endothelium-derived relaxing factor in human endothelial cells.
Biochemical and biophysical research communications 1992;186(3):1539-45.
1992: K Schmidt; P Klatt; W F Graier; G M Kostner; W R Kukovetz
High-density lipoprotein antagonizes the inhibitory effects of oxidized low-density lipoprotein and lysolecithin on soluble guanylyl cyclase.
Biochemical and biophysical research communications 1992;182(1):302-8.
1992: W F Graier; K Schmidt; W R Kukovetz
Is the bradykinin-induced Ca2+ influx and the formation of endothelium-derived relaxing factor mediated by a G protein?
European journal of pharmacology 1992;225(1):43-9.
1992: W R Kukovetz; W F Graier; K Groschner
Contribution of agonist-induced hyperpolarization to Ca2+ influx and formation of EDRF in vascular endothelial cells.
Japanese journal of pharmacology 1992;58 Suppl 2():213P-219P.
1991: W F Graier; K Schmidt; W R Kukovetz
Bradykinin-induced Ca(2+)-influx into cultured aortic endothelial cells is not regulated by inositol 1,4,5-trisphosphate or inositol 1,3,4,5-tetrakisphosphate.
Second messengers and phosphoproteins 1991;13(4):187-97.
1991: K Schmidt; W F Graier; G M Kostner; B Mayer; E Böhme; W R Kukovetz
Oxidized low-density lipoprotein antagonizes the activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor but does not interfere with its biosynthesis.
Cellular signalling 1991;3(4):361-7.
1990: K Schmidt; W F Graier; G M Kostner; B Mayer; W R Kukovetz
Activation of soluble guanylate cyclase by nitrovasodilators is inhibited by oxidized low-density lipoprotein.
Biochemical and biophysical research communications 1990;172(2):614-9.
1990: W F Graier; K Schmidt; W R Kukovetz
Effect of sodium fluoride on cytosolic free Ca2(+)-concentrations and cGMP-levels in endothelial cells.
Cellular signalling 1990;2(4):369-75.
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