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Erik Westein

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Erik Westein; Jean-Philippe Frimat; Marijke J E Kuijpers; Albert van den Berg; Andries D van der Meer; Johan W M Heemskerk
Atherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner.
Erik Westein; Moniek Lamers; Judith M E M Cosemans; Susanne de Witt; Johan W M Heemskerk
Monitoring in vitro thrombus formation with novel microfluidic devices.
Andreas Straub; Hans Peter Wendel; Erik Westein; Yuping Yuan; Carly Selan; Nicole Bassler; Shala Dezfouli; Michael J Hickey; Jan David Hohmann; Shaun Jackson; Fu Jia; Stefanie Krajewski; Julia Kurz; Harshal Nandurkar; Karlheinz Peter
Evidence of platelet activation at medically used hypothermia and mechanistic data indicating ADP as a key mediator and therapeutic target.

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All Publications

2013: Erik Westein; Jean-Philippe Frimat; Marijke J E Kuijpers; Albert van den Berg; Andries D van der Meer; Johan W M Heemskerk
Atherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(4):1357-62.
2012: Erik Westein; Moniek Lamers; Judith M E M Cosemans; Susanne de Witt; Johan W M Heemskerk
Monitoring in vitro thrombus formation with novel microfluidic devices.
Platelets 2012;23(7):501-9.
2011: Andreas Straub; Hans Peter Wendel; Erik Westein; Yuping Yuan; Carly Selan; Nicole Bassler; Shala Dezfouli; Michael J Hickey; Jan David Hohmann; Shaun Jackson; Fu Jia; Stefanie Krajewski; Julia Kurz; Harshal Nandurkar; Karlheinz Peter
Evidence of platelet activation at medically used hypothermia and mechanistic data indicating ADP as a key mediator and therapeutic target.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(7):1607-16.
2011: Francisco J Tovar-Lopez; Gary Rosengarten; Khashayar Khoshmanesh; Erik Westein; Shaun P Jackson; Warwick S Nesbitt; Arnan Mitchell
Structural and hydrodynamic simulation of an acute stenosis-dependent thrombosis model in mice.
Journal of biomechanics 2011;44(6):1031-9.
2010: Sapna Devi; Michael P Kuligowski; Rain Y Q Kwan; Erik Westein; Shaun P Jackson; A Richard Kitching; Michael J Hickey
Platelet recruitment to the inflamed glomerulus occurs via an alphaIIbbeta3/GPVI-dependent pathway.
The American journal of pathology 2010;177(3):1131-42.
2010: Francisco Javier Tovar-Lopez; Gary Rosengarten; Erik Westein; Khashayar Khoshmanesh; Shaun P Jackson; Arnan Mitchell; Warwick S Nesbitt
A microfluidics device to monitor platelet aggregation dynamics in response to strain rate micro-gradients in flowing blood.
Lab on a chip 2010;10(3):291-302.
2009: Shaun P Jackson; Warwick S Nesbitt; Erik Westein
Dynamics of platelet thrombus formation.
Journal of thrombosis and haemostasis : JTH 2009;7 Suppl 1():17-20.
2009: Warwick S Nesbitt; Erik Westein; Francisco Javier Tovar-Lopez; Elham Tolouei; Arnan Mitchell; Jia Fu; Josie Carberry; Andreas Fouras; Shaun P Jackson
A shear gradient-dependent platelet aggregation mechanism drives thrombus formation.
Nature medicine 2009;15(6):665-73.
2008: Akiko Ono; Erik Westein; Sarah Hsiao; Warwick S Nesbitt; Justin R Hamilton; Simone M Schoenwaelder; Shaun P Jackson
Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth.
Blood 2008;112(1):90-9.
2007: Mhairi Maxwell; Erik Westein; Warwick S Nesbitt; Simon Giuliano; Sacha M Dopheide; Shaun P Jackson
Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation.
Blood 2007;109(2):566-76.
2005: C J Schooten; Pernilla Tjernberg; Erik Westein; Virginie Terraube; Giancarlo Castaman; J A Mourik; Martine J Hollestelle; Hans L Vos; Rogier M Bertina; H M Berg; J C J Eikenboom; Peter J Lenting; Cécile V Denis
Cysteine-mutations in von Willebrand factor associated with increased clearance.
Journal of thrombosis and haemostasis : JTH 2005;3(10):2228-37.
2005: Patricia P E M Spijkers; Paula da Costa Martins; Erik Westein; Carl G Gahmberg; Jaap-Jan Zwaginga; Peter J Lenting
LDL-receptor-related protein regulates beta2-integrin-mediated leukocyte adhesion.
Blood 2005;105(1):170-7.
2004: Peter J Lenting; Erik Westein; Virginie Terraube; Anne-Sophie Ribba; Eric G Huizinga; Dominique Meyer; Philip G de Groot; Cécile V Denis
An experimental model to study the in vivo survival of von Willebrand factor. Basic aspects and application to the R1205H mutation.
The Journal of biological chemistry 2004;279(13):12102-9.
2003: Roland A Romijn; Erik Westein; Barend Bouma; Marion E Schiphorst; Jan J Sixma; Peter J Lenting; Eric G Huizinga
Mapping the collagen-binding site in the von Willebrand factor-A3 domain.
The Journal of biological chemistry 2003;278(17):15035-9.
2002: Erik Westein; Cécile V Denis; Bonno N Bouma; Peter J Lenting
The alpha -chains of C4b-binding protein mediate complex formation with low density lipoprotein receptor-related protein.
The Journal of biological chemistry 2002;277(4):2511-6.