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alejandro villagra

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Je-In Youn; Scott J Antonia; Pingyan Cheng; Michelle Collazo; Thomas Condamine; Mayer Fishman; Pedro Horna; Vinit Kumar; Judith C McCaffrey; Yulia Nefedova; Amod Sarnaik; Eduardo Sotomayor; alejandro villagra; Dmitry I Gabrilovich
Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer.
Fengdong Cheng; Pedro Horna; Javier Pinilla-Ibarz; Eva Sahakian; Said Sebti; Bijal Shah; Mitchell Smith; Jianguo Tao; alejandro villagra; Hongwei Wang; Zi Wang; Karrune V Woan; Eduardo M Sotomayor
Stat3 inhibition augments the immunogenicity of B-cell lymphoma cells, leading to effective antitumor immunity.
Zhigang Yuan; alejandro villagra; Lirong Peng; Domenico Coppola; Michele Glozak; Eduardo M Sotomayor; Jiandong Chen; William Stratton Lane; Edward Seto
The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions.

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All Publications

2013: Je-In Youn; Scott J Antonia; Pingyan Cheng; Michelle Collazo; Thomas Condamine; Mayer Fishman; Pedro Horna; Vinit Kumar; Judith C McCaffrey; Yulia Nefedova; Amod Sarnaik; Eduardo Sotomayor; alejandro villagra; Dmitry I Gabrilovich
Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer.
Nature immunology 2013;14(3):211-20.
2012: Fengdong Cheng; Pedro Horna; Javier Pinilla-Ibarz; Eva Sahakian; Said Sebti; Bijal Shah; Mitchell Smith; Jianguo Tao; alejandro villagra; Hongwei Wang; Zi Wang; Karrune V Woan; Eduardo M Sotomayor
Stat3 inhibition augments the immunogenicity of B-cell lymphoma cells, leading to effective antitumor immunity.
Cancer research 2012;72(17):4440-8.
2010: Zhigang Yuan; alejandro villagra; Lirong Peng; Domenico Coppola; Michele Glozak; Eduardo M Sotomayor; Jiandong Chen; William Stratton Lane; Edward Seto
The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions.
Molecular and cellular biology 2010;30(12):3004-15.
2010: alejandro villagra; E M Sotomayor; Edward Seto
Histone deacetylases and the immunological network: implications in cancer and inflammation.
Oncogene 2010;29(2):157-73.
2010: Jason A Dubovsky; alejandro villagra; John Joseph Powers; Hong-Wei Wang; Javier Pinilla-Ibarz; Eduardo M Sotomayor
Circumventing immune tolerance through epigenetic modification.
Current pharmaceutical design 2010;16(3):268-76.
2009: Danielle N Yarde; Vasco Oliveira; Linda Mathews; Xingyu Wang; alejandro villagra; David Boulware; Kenneth Shain; Lori A Hazlehurst; Melissa Alsina; Dung-Tsa Chen; Amer A Beg; William S Dalton
Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma.
Cancer research 2009;69(24):9367-75.
2009: Ildelfonso Vicente-Suarez; Jason Brayer; alejandro villagra; Fengdong Cheng; Eduardo M Sotomayor
TLR5 ligation by flagellin converts tolerogenic dendritic cells into activating antigen-presenting cells that preferentially induce T-helper 1 responses.
Immunology letters 2009;125(2):114-8.
2009: Fernando Cruzat; Berta Henriquez; alejandro villagra; Matias Hepp; Jane B Lian; Andre J van Wijnen; Janet L Stein; Anthony N Imbalzano; Gary S Stein; Martin Montecino
SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2.
Biochemistry 2009;48(30):7287-95.
2009: alejandro villagra; Fengdong Cheng; Hong-Wei Wang; Ildelfonso Suarez; Michelle Glozak; Michelle Maurin; Danny Nguyen; Kenneth L Wright; Peter W Atadja; Kapil N Bhalla; Javier Pinilla-Ibarz; Edward Seto; Eduardo M Sotomayor
The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance.
Nature immunology 2009;10(1):92-100.
2007: alejandro villagra; Natalia Ulloa; Xiaohong Zhang; Zhigang Yuan; Eduardo M Sotomayor; Edward Seto
Histone deacetylase 3 down-regulates cholesterol synthesis through repression of lanosterol synthase gene expression.
The Journal of biological chemistry 2007;282(49):35457-70.
2006: alejandro villagra; Fernando Cruzat; Loreto Carvallo; Roberto Paredes; Juan Olate; Andre J van Wijnen; Gary S Stein; Jane B Lian; Janet L Stein; Anthony N Imbalzano; Martin Montecino
Chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require CCAAT/enhancer-binding protein beta-dependent recruitment of SWI/SNF activity.
The Journal of biological chemistry 2006;281(32):22695-706.
2006: Heehyoung Lee; Nilanjan Sengupta; alejandro villagra; Natalie Rezai-Zadeh; Edward Seto
Histone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradation.
Molecular and cellular biology 2006;26(14):5259-69.
2004: Roberto Paredes; Gloria Arriagada; Fernando Cruzat; alejandro villagra; Juan Olate; Kaleem Zaidi; Andre J van Wijnen; Jane B Lian; Gary S Stein; Janet L Stein; Martin Montecino
Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells.
Molecular and cellular biology 2004;24(20):8847-61.
2003: Jose Sierra; alejandro villagra; Roberto Paredes; Fernando Cruzat; Soraya Gutierrez; Amjad Javed; Gloria Arriagada; Juan Olate; Maria Imschenetzky; Andre J van Wijnen; Jane B Lian; Gary S Stein; Janet L Stein; Martin Montecino
Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity.
Molecular and cellular biology 2003;23(9):3339-51.
2002: alejandro villagra; José Gutiérrez; Roberto Paredes; José Sierra; Marcia Puchi; Maria Imschenetzky; Andre van Wijnen Av; Jane Lian; Gary Stein; Janet Stein; Martin Montecino
Reduced CpG methylation is associated with transcriptional activation of the bone-specific rat osteocalcin gene in osteoblasts.
Journal of cellular biochemistry 2002;85(1):112-22.