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Goncalo Abecasis

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Genes & Molecular Sequences

Physiology

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Genetics, Population

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Publications

TOP 3
Osorio D Meirelles; Serena Sanna; Toshiko Tanaka; Hsih-Te Yang; Goncalo Abecasis; Francesco Cucca; Jun Ding; Dawood B Dudekula; Luigi Ferrucci; David Schlessinger
SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits.
Jian Kang; Goncalo Abecasis; Kuan-Chieh Huang; Yunfei Wang; Zheng Xu; Yun Li
AbCD: arbitrary coverage design for sequencing-based genetic studies.
Jeroen R Huyghe; Roxann Ingersoll; Anne U Jackson; Hyun Min Kang; Johanna Kuusisto; Markku Laakso; Hua Ling; Ivy McMullen; Goncalo Abecasis; Michael Boehnke; Martin L Buchkovich; Henna Cederberg; Peter S Chines; Francis S Collins; Mark J Daly; Kimberly F Doheny; Marie P Fogarty; Christian Fuchsberger; Benjamin M Neale; Elizabeth W Pugh; Jane M Romm; Laura J Scott; Xueling Sim; Alena Stančáková; Heather M Stringham; Tanya M Teslovich; Richard M Watanabe; Lingyao Yang; Karen L Mohlke
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion.

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All Publications

2013: Osorio D Meirelles; Serena Sanna; Toshiko Tanaka; Hsih-Te Yang; Goncalo Abecasis; Francesco Cucca; Jun Ding; Dawood B Dudekula; Luigi Ferrucci; David Schlessinger
SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits.
European journal of human genetics : EJHG 2013;21(6):673-9.
2013: Jian Kang; Goncalo Abecasis; Kuan-Chieh Huang; Yunfei Wang; Zheng Xu; Yun Li
AbCD: arbitrary coverage design for sequencing-based genetic studies.
Bioinformatics (Oxford, England) 2013;29(6):799-801.
2013: Jeroen R Huyghe; Roxann Ingersoll; Anne U Jackson; Hyun Min Kang; Johanna Kuusisto; Markku Laakso; Hua Ling; Ivy McMullen; Goncalo Abecasis; Michael Boehnke; Martin L Buchkovich; Henna Cederberg; Peter S Chines; Francis S Collins; Mark J Daly; Kimberly F Doheny; Marie P Fogarty; Christian Fuchsberger; Benjamin M Neale; Elizabeth W Pugh; Jane M Romm; Laura J Scott; Xueling Sim; Alena Stančáková; Heather M Stringham; Tanya M Teslovich; Richard M Watanabe; Lingyao Yang; Karen L Mohlke
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion.
Nature genetics 2013;45(2):197-201.
2013: Wenqing Fu; Stacey Gabriel; Goo Jun; Hyun Min Kang; Suzanne M Leal; Deborah A Nickerson; Timothy D O'Connor; Jay Shendure; Mark J Rieder; Goncalo Abecasis; David Altshuler; Michael Bamshad; Joshua M Akey
Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants.
Nature 2013;493(7431):216-20.
2012: Goncalo Abecasis; Adam Auton; Lisa D Brooks; Mark A DePristo; Richard M Durbin; Robert E Handsaker; Hyun Min Kang; Gabor T Marth; Gil McVean
An integrated map of genetic variation from 1,092 human genomes.
Nature 2012;491(7422):56-65.
2012: Jacob A Tennessen; Goncalo Abecasis; Joshua M Akey; David Altshuler; Michael Bamshad; Abigail W Bigham; Eric Boerwinkle; Carlos D Bustamante; Ron Do; Wenqing Fu; Stacey Gabriel; Simon Gravel; Daniel Jordan; Goo Jun; Hyun Min Kang; Eimear E Kenny; Suzanne M Leal; Xiaoming Liu; Sean McGee; Deborah A Nickerson; Timothy D O'Connor; Mark J Rieder; Shamil Sunyaev
Evolution and functional impact of rare coding variation from deep sequencing of human exomes.
Science (New York, N.Y.) 2012;337(6090):64-9.
2011: Petr Danecek; Mark A DePristo; Richard Durbin; Robert E Handsaker; Gerton Lunter; Gabor T Marth; Gil McVean; Stephen T Sherry; Goncalo Abecasis; Cornelis A Albers; Adam Auton; Eric Banks
The variant call format and VCFtools.
Bioinformatics (Oxford, England) 2011;27(15):2156-8.
2011: Yun Li; Carlo Sidore; Hyun Min Kang; Michael Boehnke; Goncalo Abecasis
Low-coverage sequencing: implications for design of complex trait association studies.
Genome research 2011;21(6):940-51.
2011: Jin Zheng; Yun Li; Goncalo Abecasis; Paul Scheet
A comparison of approaches to account for uncertainty in analysis of imputed genotypes.
Genetic epidemiology 2011;35(2):102-10.
2011: María Brión; Manuel Sanchez-Salorio; Marta Cortón; Maria de la Fuente; Belen Pazos; Mohammad Othman; Anand Swaroop; Goncalo Abecasis; Beatriz Sobrino; Angel Carracedo
Genetic association study of age-related macular degeneration in the Spanish population.
Acta ophthalmologica 2011;89(1):e12-22.
2010: Yun Li; Cristen J Willer; Jun Ding; Paul Scheet; Goncalo Abecasis
MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes.
Genetic epidemiology 2010;34(8):816-34.
2010: Philip Stuart; Rajan P Nair; Eva Ellinghaus; Jun Ding; Trilokraj Tejasvi; Johann Gudjonsson; Yun Li; Stephan Weidinger; Bernadette Eberlein; Christian Gieger; H-Erich Wichmann; Manfred Kunz; Robert W Ike; Gerald G Krueger; Anne M Bowcock; Ulrich Mrowietz; Henry W Lim; John J Voorhees; Goncalo Abecasis; Michael Weichenthal; Andre Franke; Proton Rahman; Dafna D Gladman; James T Elder
Genome-wide association analysis identifies three psoriasis susceptibility loci.
Nature genetics 2010;42(11):1000-4.
2010: Antonio Terracciano; Toshiko Tanaka; Angelina R Sutin; serena Sanna; Barbara Deiana; Sandra Lai; Manuela Uda; David Schlessinger; Goncalo Abecasis; Luigi Ferrucci; Paul T Costa
Genome-wide association scan of trait depression.
Biological psychiatry 2010;68(9):811-7.
2010: Keith H Baratz; Nirubol Tosakulwong; Euijung Ryu; William L Brown; Kari E H Branham; Wei Chen; Khoa D Tran; Katharina E Schmid-Kubista; John R Heckenlively; Anand Swaroop; Goncalo Abecasis; Kent R Bailey; Albert O Edwards
E2-2 protein and Fuchs's corneal dystrophy.
The New England journal of medicine 2010;363(11):1016-24.
2010: Cristen J Willer; Yun Li; Goncalo Abecasis
METAL: fast and efficient meta-analysis of genomewide association scans.
Bioinformatics (Oxford, England) 2010;26(17):2190-1.
2010: Johann Gudjonsson; Jun Ding; Andrew Johnston; Trilokraj Tejasvi; Andrew M Guzman; Rajan P Nair; John J Voorhees; Goncalo Abecasis; James T Elder
Assessment of the psoriatic transcriptome in a large sample: additional regulated genes and comparisons with in vitro models.
The Journal of investigative dermatology 2010;130(7):1829-40.
2010: Antonio Terracciano; serena Sanna; Manuela Uda; B Deiana; G Usala; Fabio Busonero; A Maschio; M Scally; N Patriciu; W-M Chen; M A Distel; E P Slagboom; Dorret I Boomsma; Sandra Maria Villafuerte Monje; E Sliwerska; Margit Burmeister; N Amin; A C J W Janssens; C M van Duijn; David Schlessinger; Goncalo Abecasis; Paul T Costa
Genome-wide association scan for five major dimensions of personality.
Molecular psychiatry 2010;15(6):647-56.
2010: James T Elder; Allen T Bruce; Johann Gudjonsson; Andrew Johnston; Philip Stuart; Trilokraj Tejasvi; John J Voorhees; Goncalo Abecasis; Rajan P Nair
Molecular dissection of psoriasis: integrating genetics and biology.
The Journal of investigative dermatology 2010;130(5):1213-26.
2009: Antonio Terracciano; Lenuta Balaci; Jason Thayer; Matthew Scally; Sarah Kokinos; Luigi Ferrucci; Toshiko Tanaka; Alan B Zonderman; serena Sanna; Nazario Olla; Maria Antonietta Zuncheddu; Silvia Naitza; Fabio Busonero; Manuela Uda; David Schlessinger; Goncalo Abecasis; Paul T Costa
Variants of the serotonin transporter gene and NEO-PI-R Neuroticism: No association in the BLSA and SardiNIA samples.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(8):1070-7.
2009: Johann Gudjonsson; Jun Ding; Xing Li; Rajan P Nair; Trilokraj Tejasvi; Zhaohui S Qin; Debashis Ghosh; Abhishek Aphale; Deborah L Gumucio; John J Voorhees; Goncalo Abecasis; James T Elder
Global gene expression analysis reveals evidence for decreased lipid biosynthesis and increased innate immunity in uninvolved psoriatic skin.
The Journal of investigative dermatology 2009;129(12):2795-804.
2009: John C Chambers; Weihua Zhang; Yun Li; Joban Sehmi; Mark N Wass; Delilah Zabaneh; Clive J Hoggart; Henry Bayele; Mark I McCarthy; Leena Peltonen; Nelson B Freimer; Kaila Surjit Srai; Patrick H Maxwell; Michael J E Sternberg; Aimo Ruokonen; Goncalo Abecasis; Marjo-Riitta Jarvelin; James Scott; Paul Elliott; Jaspal S Kooner
Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels.
Nature genetics 2009;41(11):1170-2.
2009: Bin Xu; Abigail Woodroffe; Laura Rodriguez-Murillo; J Louw Roos; Elizabeth J van Rensburg; Goncalo Abecasis; Joseph A Gogos; Maria Karayiorgou
Elucidating the genetic architecture of familial schizophrenia using rare copy number variant and linkage scans.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(39):16746-51.
2009: Weihua Guan; Liming Liang; Michael Boehnke; Goncalo Abecasis
Genotype-based matching to correct for population stratification in large-scale case-control genetic association studies.
Genetic epidemiology 2009;33(6):508-17.
2009: Heng Li; Bob Handsaker; Alec Wysoker; Tim Fennell; Jue Ruan; Nils Homer; Gabor Marth; Goncalo Abecasis; Richard Durbin
The Sequence Alignment/Map format and SAMtools.
Bioinformatics (Oxford, England) 2009;25(16):2078-9.
2009: Bing-Jian Feng; Liang-Dan Sun; Razieh Soltani-Arabshahi; Anne M Bowcock; Rajan P Nair; Philip Stuart; James T Elder; Steven J Schrodi; Ann B Begovich; Goncalo Abecasis; Xue-Jun Zhang; Kristina P Callis-Duffin; Gerald G Krueger; David E Goldgar
Multiple Loci within the major histocompatibility complex confer risk of psoriasis.
PLoS genetics 2009;5(8):e1000606.
2009: serena Sanna; Fabio Busonero; Andrea Maschio; Patrick F McArdle; Gianluca Usala; Mariano Dei; Sandra Lai; Antonella Mulas; Maria Grazia Piras; Luciana Perseu; Marco Masala; Mara Marongiu; Laura Crisponi; Silvia Naitza; Renzo Galanello; Goncalo Abecasis; Alan R Shuldiner; David Schlessinger; Antonio Cao; Manuela Uda
Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.
Human molecular genetics 2009;18(14):2711-8.
2009: Kirill V Tarasov; serena Sanna; ANGELO SCUTERI; James B Strait; Marco Orrù; Afshin Parsa; Ping-I Lin; Andrea Maschio; Sandra Lai; Maria Grazia Piras; Marco Masala; Toshiko Tanaka; Wendy S Post; Jeffrey R O'Connell; David Schlessinger; Antonio Cao; Ramaiah Nagaraja; Braxton D Mitchell; Goncalo Abecasis; Alan R Shuldiner; Manuela Uda; Edward G Lakatta; Samer S Najjar
COL4A1 is associated with arterial stiffness by genome-wide association scan.
Circulation. Cardiovascular genetics 2009;2(2):151-8.
2009: Toshiko Tanaka; Paul Scheet; Betti Giusti; Stefania Bandinelli; Maria Grazia Piras; Gianluca Usala; Sandra Lai; Antonella Mulas; Anna Maria Corsi; Anna Vestrini; Francesco Sofi; Anna Maria Gori; Rosanna Abbate; Jack Guralnik; Andrew Singleton; Goncalo Abecasis; David Schlessinger; Manuela Uda; Luigi Ferrucci
Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations.
American journal of human genetics 2009;84(4):477-82.
2009: William Cookson; Liming Liang; Goncalo Abecasis; Miriam Moffatt; Mark Lathrop
Mapping complex disease traits with global gene expression.
Nature reviews. Genetics 2009;10(3):184-94.
2009: Lucy Huang; Yun Li; Andrew Singleton; John Hardy; Goncalo Abecasis; Noah A Rosenberg; Paul Scheet
Genotype-imputation accuracy across worldwide human populations.
American journal of human genetics 2009;84(2):235-50.
2009: Rajan P Nair; Kristina Callis Duffin; Cynthia Helms; Jun Ding; Philip Stuart; David Goldgar; Johann Gudjonsson; Yun Li; Trilokraj Tejasvi; Bing-Jian Feng; Andreas Ruether; Stefan Schreiber; Michael Weichenthal; Dafna Gladman; Proton Rahman; Steven J Schrodi; Sampath Prahalad; Stephen L Guthery; Judith Fischer; Wilson Liao; Pui-Yan Kwok; Alan Menter; G Mark Lathrop; Carol A Wise; Ann B Begovich; John J Voorhees; James T Elder; Gerald G Krueger; Anne M Bowcock; Goncalo Abecasis
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
Nature genetics 2009;41(2):199-204.
2009: Wei Chen; Liming Liang; Goncalo Abecasis
GWAS GUI: graphical browser for the results of whole-genome association studies with high-dimensional phenotypes.
Bioinformatics (Oxford, England) 2009;25(2):284-5.
2009: Yun Li; Cristen J Willer; serena Sanna; Goncalo Abecasis
Genotype imputation.
Annual review of genomics and human genetics 2009;10():387-406.
2009: Liming Liang; Wei-Min Chen; Pak C Sham; Goncalo Abecasis
Variance components linkage analysis with repeated measurements.
Human heredity 2009;67(4):237-47.
2009: Toshiko Tanaka; Jian Shen; Goncalo Abecasis; Aliaksei Kisialiou; Jose Ordovas; Jack M Guralnik; Andrew Singleton; Stefania Bandinelli; Antonio Cherubini; Donna K Arnett; Michael Y Tsai; Luigi Ferrucci
Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study.
PLoS genetics 2009;5(1):e1000338.
2008: Kyle J Gaulton; Cristen J Willer; Yun Li; Laura J Scott; Karen N Conneely; Anne U Jackson; William L Duren; Peter S Chines; Narisu Narisu; Lori L Bonnycastle; Jingchun Luo; Maurine Tong; Andrew G Sprau; Elizabeth W Pugh; Kimberly F Doheny; Timo T Valle; Goncalo Abecasis; Jaakko Tuomilehto; Richard N Bergman; Francis S Collins; Michael Boehnke; Karen L Mohlke
Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes.
Diabetes 2008;57(11):3136-44.
2008: Karen L Mohlke; Michael Boehnke; Goncalo Abecasis
Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
Human molecular genetics 2008;17(R2):R102-8.
2008: Wei-Min Chen; Michael R Erdos; Anne U Jackson; Richa Saxena; serena Sanna; Kristi D Silver; Nicholas J Timpson; Torben Hansen; Marco Orrù; Maria Grazia Piras; Lori L Bonnycastle; Cristen J Willer; Valeriya Lyssenko; Haiqing Shen; Johanna Kuusisto; Shah Ebrahim; Natascia Sestu; William L Duren; Maria Cristina Spada; Heather M Stringham; Laura J Scott; Nazario Olla; Amy J Swift; Samer Najjar; Braxton D Mitchell; Debbie A Lawlor; George Davey Smith; Yoav Ben-Shlomo; Gitte Andersen; Knut Borch-Johnsen; Torben Jørgensen; Jouko Saramies; Timo T Valle; Thomas A Buchanan; Alan R Shuldiner; Edward Lakatta; Richard N Bergman; Manuela Uda; Jaakko Tuomilehto; Oluf Pedersen; Antonio Cao; Leif Groop; Karen L Mohlke; Markku Laakso; David Schlessinger; Francis S Collins; David Altshuler; Goncalo Abecasis; Michael Boehnke; ANGELO SCUTERI; Richard M Watanabe
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.
The Journal of clinical investigation 2008;118(7):2620-8.
2008: Lisette Arnaud-Lopez; Gianluca Usala; Graziano Ceresini; Braxton D Mitchell; Maria Grazia Pilia; Maria Grazia Piras; Natascia Sestu; Andrea Maschio; Fabio Busonero; Giuseppe Albai; Mariano Dei; Sandra Lai; Antonella Mulas; Laura Crisponi; Toshiko Tanaka; Stefania Bandinelli; Jack M Guralnik; Angela Loi; Lenuta Balaci; Gabriella Sole; Alessia Prinzis; Stefano Mariotti; Alan R Shuldiner; Antonio Cao; David Schlessinger; Manuela Uda; Goncalo Abecasis; Ramaiah Nagaraja; serena Sanna; Silvia Naitza
Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function.
American journal of human genetics 2008;82(6):1270-80.
2008: Ruth J F Loos; Cecilia M Lindgren; Shengxu Li; Eleanor Wheeler; Jing Hua Zhao; Inga Prokopenko; Michael Inouye; Rachel Freathy; Antony P Attwood; Jacques Beckmann; Sonja I Berndt; Kevin B Jacobs; STEPHEN CHANOCK; Richard Hayes; Sven Bergmann; Amanda J Bennett; Sheila A Bingham; Murielle Bochud; Morris Brown; Stéphane Cauchi; John M Connell; Cyrus Cooper; George Davey Smith; Ian Day; Christian Dina; Subhajyoti De; Emmanouil T Dermitzakis; Alex S F Doney; Katherine S Elliott; Paul Elliott; David M Evans; I Sadaf Farooqi; philippe froguel; Jilur Ghori; Christopher J Groves; Rhian Gwilliam; David Hadley; Alistair Hall; Andrew T Hattersley; Johannes Hebebrand; Iris M Heid; Claudia Lamina; Christian Gieger; Thomas Illig; Thomas Meitinger; H-Erich Wichmann; blanca herrera; Anke Hinney; Sarah E Hunt; Marjo-Riitta Jarvelin; Toby Johnson; Jennifer D M Jolley; Fredrik Karpe; Andrew Keniry; Kay-Tee Khaw; Robert N Luben; Massimo Mangino; Jonathan Marchini; Wendy L McArdle; Ralph McGinnis; David Meyre; Patricia B Munroe; Andrew D Morris; Andrew R Ness; Matthew J Neville; Alexandra C Nica; Ken K Ong; Stephen O'Rahilly; Katharine R Owen; Colin N A Palmer; Konstantinos Papadakis; Simon Potter; Anneli Pouta; Lu Qi; Joshua C Randall; Nigel W Rayner; Susan M Ring; Manjinder S Sandhu; André Scherag; Matthew A Sims; Kijoung Song; Nicole Soranzo; Elizabeth K Speliotes; Holly E Syddall; Sarah A Teichmann; Nicholas J Timpson; Jonathan H Tobias; Manuela Uda; Carla I Ganz Vogel; chris wallace; Dawn M Waterworth; Michael Weedon; Cristen J Willer; Xin Yuan; Eleftheria Zeggini; Joel N Hirschhorn; David P Strachan; Willem H Ouwehand; Mark J Caulfield; Nilesh J Samani; Timothy M Frayling; Peter Vollenweider; Gerard Waeber; Vincent Mooser; Panos Deloukas; Mark I McCarthy; Nicholas J Wareham; Inês Barroso; Kevin B Jacobs; Stephen J Chanock; Richard B Hayes; Claudia Lamina; Christian Gieger; Thomas Illig; Thomas Meitinger; H-Erich Wichmann; Peter Kraft; Susan E Hankinson; David J Hunter; Frank B Hu; Helen N Lyon; Benjamin F Voight; Martin Ridderstrale; Leif Groop; Paul Scheet; serena Sanna; Goncalo Abecasis; Giuseppe Albai; Ramaiah Nagaraja; David Schlessinger; Anne U Jackson; Jaakko Tuomilehto; Francis S Collins; Michael Boehnke; Karen L Mohlke
Common variants near MC4R are associated with fat mass, weight and risk of obesity.
Nature genetics 2008;40(6):768-75.
2008: Mark I McCarthy; Goncalo Abecasis; Lon R Cardon; David B Goldstein; Julian Little; John Ioannidis; Joel N Hirschhorn
Genome-wide association studies for complex traits: consensus, uncertainty and challenges.
Nature reviews. Genetics 2008;9(5):356-69.
2008: Guillaume Lettre; Anne U Jackson; Christian Gieger; Fredrick R Schumacher; Sonja I Berndt; serena Sanna; Susana Eyheramendy; Benjamin F Voight; Johannah L Butler; Candace Guiducci; Thomas Illig; Rachel Hackett; Iris M Heid; Kevin B Jacobs; Valeriya Lyssenko; Manuela Uda; Michael Boehnke; STEPHEN CHANOCK; Leif C Groop; Frank B Hu; Bo Isomaa; Peter Kraft; Leena Peltonen; Veikko Salomaa; David Schlessinger; David J Hunter; Richard Hayes; Goncalo Abecasis; H-Erich Wichmann; Karen L Mohlke; Joel N Hirschhorn
Identification of ten loci associated with height highlights new biological pathways in human growth.
Nature genetics 2008;40(5):584-91.
2008: Eleftheria Zeggini; Laura J Scott; Richa Saxena; Benjamin F Voight; Jonathan L Marchini; Tianle Hu; Paul I W de Bakker; Goncalo Abecasis; Peter Almgren; Gitte Andersen; Kristin Ardlie; Kristina Bengtsson Boström; Richard N Bergman; Lori L Bonnycastle; Knut Borch-Johnsen; Noël P Burtt; Hong Chen; Peter S Chines; Mark J Daly; Parimal Deodhar; Chia-Jen Ding; Alex S F Doney; William L Duren; Katherine S Elliott; Michael R Erdos; Timothy M Frayling; Rachel Freathy; Lauren Gianniny; Harald Grallert; Niels Grarup; Christopher J Groves; Candace Guiducci; Torben Hansen; Christian Herder; Graham A Hitman; Thomas Hughes; Bo Isomaa; Anne U Jackson; Torben Jørgensen; Augustine Kong; Kari Kubalanza; Finny G Kuruvilla; Johanna Kuusisto; Claudia Langenberg; Hana Lango; torsten lauritzen; Yun Li; Cecilia M Lindgren; Valeriya Lyssenko; Amanda F Marvelle; Christa Meisinger; Kristian Midthjell; Karen L Mohlke; Mario A Morken; Andrew D Morris; Narisu Narisu; Peter Nilsson; Katharine R Owen; Colin N A Palmer; Felicity Payne; John R B Perry; Elin Pettersen; Carl Platou; Inga Prokopenko; Lu Qi; Li Qin; Nigel W Rayner; Matthew Rees; Jeffrey J Roix; Anelli Sandbaek; Beverley Shields; Marketa Sjögren; Valgerdur Steinthorsdottir; Heather M Stringham; Amy J Swift; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Nicholas J Timpson; Tiinamaija Tuomi; Jaakko Tuomilehto; Mark Walker; Richard Watanabe; Michael Weedon; Cristen J Willer; Thomas Illig; Kristian Hveem; Frank B Hu; Markku Laakso; kari stefansson; Oluf Pedersen; Nicholas J Wareham; Inês Barroso; Andrew T Hattersley; Francis S Collins; Leif Groop; Mark I McCarthy; Michael Boehnke; David Altshuler
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
Nature genetics 2008;40(5):638-45.
2008: Albert O Edwards; Dequan Chen; Brooke L Fridley; Katherine M James; Yanhong Wu; Goncalo Abecasis; Anand Swaroop; Mohammad Othman; Kari E H Branham; Sudha K Iyengar; Theru A Sivakumaran; Ronald Klein; Barbara E K Klein; Nirubol Tosakulwong
Toll-like receptor polymorphisms and age-related macular degeneration.
Investigative ophthalmology & visual science 2008;49(4):1652-9.
2008: Atsuhiro Kanda; Goncalo Abecasis; Anand Swaroop
Inflammation in the pathogenesis of age-related macular degeneration.
The British journal of ophthalmology 2008;92(4):448-50.
2008: Manuela Uda; Renzo Galanello; serena Sanna; Guillaume Lettre; Vijay G Sankaran; Weimin Chen; Gianluca Usala; Fabio Busonero; Andrea Maschio; Giuseppe Albai; Maria Grazia Piras; Natascia Sestu; Sandra Lai; Mariano Dei; Antonella Mulas; Laura Crisponi; Silvia Naitza; Isadora Asunis; Manila Deiana; Ramaiah Nagaraja; Luciana Perseu; Stefania Satta; MD Cipollina; Carla Sollaino; Paolo Moi; Joel N Hirschhorn; Stuart H Orkin; Goncalo Abecasis; David Schlessinger; Antonio Cao
Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(5):1620-5.
2008: serena Sanna; Anne U Jackson; Ramaiah Nagaraja; Cristen J Willer; Wei-Min Chen; Lori L Bonnycastle; Haiqing Shen; Nicholas Timpson; Guillaume Lettre; Gianluca Usala; Peter S Chines; Heather M Stringham; Laura J Scott; Mariano Dei; Sandra Lai; Giuseppe Albai; Laura Crisponi; Silvia Naitza; Kimberly F Doheny; Elizabeth W Pugh; Yoav Ben-Shlomo; Shah Ebrahim; Debbie A Lawlor; Richard N Bergman; Richard Watanabe; Manuela Uda; Jaakko Tuomilehto; Josef Coresh; Joel N Hirschhorn; Alan R Shuldiner; David Schlessinger; Francis S Collins; George Davey Smith; Eric Boerwinkle; Antonio Cao; Michael Boehnke; Goncalo Abecasis; Karen L Mohlke
Common variants in the GDF5-UQCC region are associated with variation in human height.
Nature genetics 2008;40(2):198-203.
2008: Cristen J Willer; serena Sanna; Anne U Jackson; ANGELO SCUTERI; Lori L Bonnycastle; Robert Clarke; Simon Heath; Nicholas J Timpson; Samer S Najjar; Heather M Stringham; James Strait; William L Duren; Andrea Maschio; Fabio Busonero; Antonella Mulas; Giuseppe Albai; Amy J Swift; Mario A Morken; Narisu Narisu; Derrick Bennett; Sarah Parish; Haiqing Shen; Pilar Galan; Pierre Meneton; Serge Hercberg; Diana Zelenika; Wei-Min Chen; Yun Li; Laura J Scott; Paul A Scheet; Jouko Sundvall; Richard Watanabe; Ramaiah Nagaraja; Shah Ebrahim; Debbie A Lawlor; Yoav Ben-Shlomo; George Davey-Smith; Alan R Shuldiner; Rory Collins; Richard N Bergman; Manuela Uda; Jaakko Tuomilehto; Antonio Cao; Francis S Collins; Edward Lakatta; G Mark Lathrop; Michael Boehnke; David Schlessinger; Karen L Mohlke; Goncalo Abecasis
Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
Nature genetics 2008;40(2):161-9.
2007: Siguang Li; serena Sanna; Andrea Maschio; Fabio Busonero; Gianluca Usala; Antonella Mulas; Sandra Lai; Mariano Dei; Marco Orrù; Giuseppe Albai; Stefania Bandinelli; David Schlessinger; Edward Lakatta; ANGELO SCUTERI; Samer S Najjar; Jack Guralnik; Silvia Naitza; Laura Crisponi; Antonio Cao; Goncalo Abecasis; Luigi Ferrucci; Manuela Uda; Wei-Min Chen; Ramaiah Nagaraja
The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts.
PLoS genetics 2007;3(11):e194.
2007: Wei-Min Chen; Goncalo Abecasis
Family-based association tests for genomewide association scans.
American journal of human genetics 2007;81(5):913-26.
2007: Andrew D Skol; Laura J Scott; Goncalo Abecasis; Michael Boehnke
Optimal designs for two-stage genome-wide association studies.
Genetic epidemiology 2007;31(7):776-88.
2007: Pardis C Sabeti; Patrick Varilly; Ben Fry; Jason Lohmueller; Elizabeth Hostetter; Chris Cotsapas; Xiaohui Xie; Elizabeth H Byrne; Steven A McCarroll; Rachelle Gaudet; Stephen F Schaffner; Eric S Lander; Kelly A Frazer; Dennis G Ballinger; David R Cox; David Hinds; Laura L Stuve; Richard A Gibbs; John W Belmont; Andrew Boudreau; Paul Hardenbol; Suzanne M Leal; Shiran Pasternak; David A Wheeler; Thomas D Willis; Fuli Yu; Huanming Yang; Changqing Zeng; Yang Gao; Haoran Hu; Weitao Hu; Chaohua Li; Wei Lin; Siqi Liu; Hao Pan; Xiaoli Tang; Jian Wang; Wei Wang; Jun Yu; Bo Zhang; Qingrun Zhang; Hongbin Zhao; Hui Zhao; Jun Zhou; Stacey B Gabriel; Rachel Barry; Brendan Blumenstiel; Amy Camargo; Matthew Defelice; Maura Faggart; Mary Goyette; Supriya Gupta; Jamie Moore; Huy Nguyen; Robert C Onofrio; Melissa Parkin; Jessica Roy; Erich Stahl; Ellen Winchester; Liuda Ziaugra; David Altshuler; Yan Shen; Zhijian Yao; Wei Huang; Xun Chu; Yungang He; Li Jin; Yangfan Liu; Yayun Shen; Weiwei Sun; Haifeng Wang; Yi Wang; Ying Wang; Xiaoyan Xiong; Liang Xu; Mary Waye; Stephen K W Tsui; Hong Xue; J Tze-Fei Wong; Luana M Galver; Jian-Bing Fan; Kevin Gunderson; Sarah S Murray; Arnold R Oliphant; Mark S Chee; Alexandre Montpetit; Fanny Chagnon; Vincent Ferretti; Martin Leboeuf; Jean-François Olivier; Michael S Phillips; Stéphanie Roumy; Clémentine Sallée; Andrei Verner; Thomas J Hudson; Pui-Yan Kwok; Dongmei Cai; Daniel C Koboldt; Raymond D Miller; Ludmila Pawlikowska; Patricia Taillon-Miller; Ming Xiao; Lap-Chee Tsui; William Mak; You Qiang Song; Paul K H Tam; Yusuke Nakamura; Takahisa Kawaguchi; Takuya Kitamoto; Takashi Morizono; Atsushi Nagashima; Yozo Ohnishi; Akihiro Sekine; Toshihiro Tanaka; Tatsuhiko Tsunoda; Panos Deloukas; Christine P Bird; Marcos Delgado; Emmanouil T Dermitzakis; Rhian Gwilliam; Sarah Hunt; Jonathan Morrison; Don Powell; Barbara E Stranger; Pamela Whittaker; David R Bentley; Mark J Daly; Paul I W de Bakker; Jeff Barrett; Yves R Chretien; Julian Maller; Steve McCarroll; Nick Patterson; Itsik Pe'er; Alkes Price; Shaun Purcell; Daniel J Richter; Pardis Sabeti; Richa Saxena; Stephen F Schaffner; Pak C Sham; Patrick Varilly; David Altshuler; Lincoln D Stein; Lalitha Krishnan; Albert Vernon Smith; Marcela K Tello-Ruiz; Gudmundur A Thorisson; Aravinda Chakravarti; Peter E Chen; David J Cutler; Carl S Kashuk; Shin Lin; Goncalo Abecasis; Weihua Guan; Yun Li; Heather M Munro; Zhaohui Steve Qin; Daryl J Thomas; Gilean McVean; Adam Auton; Leonardo Bottolo; Niall Cardin; Susana Eyheramendy; Colin Freeman; Jonathan Marchini; Simon Myers; Chris Spencer; Matthew Stephens; Peter Donnelly; Lon R Cardon; Geraldine Clarke; David M Evans; Andrew P Morris; Bruce S Weir; Tatsuhiko Tsunoda; Todd A Johnson; James C Mullikin; Stephen T Sherry; Michael Feolo; Andrew Skol; Houcan Zhang; Changqing Zeng; Hui Zhao; Ichiro Matsuda; Yoshimitsu Fukushima; Darryl R Macer; Eiko Suda; Charles N Rotimi; Clement Adebamowo; Ike Ajayi; Toyin Aniagwu; Patricia A Marshall; Chibuzor Nkwodimmah; Charmaine D M Royal; Mark F Leppert; Missy Dixon; Andy Peiffer; Renzong Qiu; Alastair Kent; Kazuto Kato; Norio Niikawa; ISAAC FOLORUNSO ADEWOLE; Bartha M Knoppers; Morris W Foster; Ellen Wright Clayton; Jessica Watkin; Richard A Gibbs; John W Belmont; Donna Muzny; Lynne Nazareth; Erica Sodergren; George Weinstock; David A Wheeler; Imtaz Yakub; Stacey B Gabriel; Robert C Onofrio; Daniel J Richter; Liuda Ziaugra; Bruce W Birren; Mark J Daly; David Altshuler; Richard K Wilson; Lucinda L Fulton; Jane Rogers; John Burton; Nigel P Carter; Christopher M Clee; Mark Griffiths; Matthew C Jones; Kirsten McLay; Robert W Plumb; Mark T Ross; Sarah K Sims; David L Willey; Zhu Chen; Hua Han; Le Kang; Martin Godbout; John C Wallenburg; Paul L'Archevêque; Guy Bellemare; Koji Saeki; Hongguang Wang; Daochang An; Hongbo Fu; Qing Li; Zhen Wang; Renwu Wang; Arthur L Holden; Lisa D Brooks; Jean E McEwen; Mark S Guyer; Vivian Ota Wang; Jane L Peterson; Michael Shi; Jack Spiegel; Lawrence M Sung; Lynn F Zacharia; Francis S Collins; Karen Kennedy; Ruth Jamieson; John Stewart
Genome-wide detection and characterization of positive selection in human populations.
Nature 2007;449(7164):913-8.
2007: Kelly A Frazer; Dennis G Ballinger; David R Cox; David Hinds; Laura L Stuve; Richard A Gibbs; John W Belmont; Andrew Boudreau; Paul Hardenbol; Suzanne M Leal; Shiran Pasternak; David A Wheeler; Thomas D Willis; Fuli Yu; Huanming Yang; Changqing Zeng; Yang Gao; Haoran Hu; Weitao Hu; Chaohua Li; Wei Lin; Siqi Liu; Hao Pan; Xiaoli Tang; Jian Wang; Wei Wang; Jun Yu; Bo Zhang; Qingrun Zhang; Hongbin Zhao; Hui Zhao; Jun Zhou; Stacey B Gabriel; Rachel Barry; Brendan Blumenstiel; Amy Camargo; Matthew Defelice; Maura Faggart; Mary Goyette; Supriya Gupta; Jamie Moore; Huy Nguyen; Robert C Onofrio; Melissa Parkin; Jessica Roy; Erich Stahl; Ellen Winchester; Liuda Ziaugra; David Altshuler; Yan Shen; Zhijian Yao; Wei Huang; Xun Chu; Yungang He; Li Jin; Yangfan Liu; Yayun Shen; Weiwei Sun; Haifeng Wang; Yi Wang; Ying Wang; Xiaoyan Xiong; Liang Xu; Mary Waye; Stephen K W Tsui; Hong Xue; J Tze-Fei Wong; Luana M Galver; Jian-Bing Fan; Kevin Gunderson; Sarah S Murray; Arnold R Oliphant; Mark S Chee; Alexandre Montpetit; Fanny Chagnon; Vincent Ferretti; Martin Leboeuf; Jean-François Olivier; Michael S Phillips; Stéphanie Roumy; Clémentine Sallée; Andrei Verner; Thomas J Hudson; Pui-Yan Kwok; Dongmei Cai; Daniel C Koboldt; Raymond D Miller; Ludmila Pawlikowska; Patricia Taillon-Miller; Ming Xiao; Lap-Chee Tsui; William Mak; You Qiang Song; Paul K H Tam; Yusuke Nakamura; Takahisa Kawaguchi; Takuya Kitamoto; Takashi Morizono; Atsushi Nagashima; Yozo Ohnishi; Akihiro Sekine; Toshihiro Tanaka; Tatsuhiko Tsunoda; Panos Deloukas; Christine P Bird; Marcos Delgado; Emmanouil T Dermitzakis; Rhian Gwilliam; Sarah Hunt; Jonathan Morrison; Don Powell; Barbara E Stranger; Pamela Whittaker; David R Bentley; Mark J Daly; Paul I W de Bakker; Jeff Barrett; Yves R Chretien; Julian Maller; Steve McCarroll; Nick Patterson; Itsik Pe'er; Alkes Price; Shaun Purcell; Daniel J Richter; Pardis Sabeti; Richa Saxena; Stephen F Schaffner; Pak C Sham; Patrick Varilly; David Altshuler; Lincoln D Stein; Lalitha Krishnan; Albert Vernon Smith; Marcela K Tello-Ruiz; Gudmundur A Thorisson; Aravinda Chakravarti; Peter E Chen; David J Cutler; Carl S Kashuk; Shin Lin; Goncalo Abecasis; Weihua Guan; Yun Li; Heather M Munro; Zhaohui Steve Qin; Daryl J Thomas; Gilean McVean; Adam Auton; Leonardo Bottolo; Niall Cardin; Susana Eyheramendy; Colin Freeman; Jonathan Marchini; Simon Myers; Chris Spencer; Matthew Stephens; Peter Donnelly; Lon R Cardon; Geraldine Clarke; David M Evans; Andrew P Morris; Bruce S Weir; Tatsuhiko Tsunoda; James C Mullikin; Stephen T Sherry; Michael Feolo; Andrew Skol; Houcan Zhang; Changqing Zeng; Hui Zhao; Ichiro Matsuda; Yoshimitsu Fukushima; Darryl R Macer; Eiko Suda; Charles N Rotimi; Clement Adebamowo; Ike Ajayi; Toyin Aniagwu; Patricia A Marshall; Chibuzor Nkwodimmah; Charmaine D M Royal; Mark F Leppert; Missy Dixon; Andy Peiffer; Renzong Qiu; Alastair Kent; Kazuto Kato; Norio Niikawa; ISAAC FOLORUNSO ADEWOLE; Bartha M Knoppers; Morris W Foster; Ellen Wright Clayton; Jessica Watkin; Richard A Gibbs; John W Belmont; Donna Muzny; Lynne Nazareth; Erica Sodergren; George M Weinstock; David A Wheeler; Imtaz Yakub; Stacey B Gabriel; Robert C Onofrio; Daniel J Richter; Liuda Ziaugra; Bruce W Birren; Mark J Daly; David Altshuler; Richard K Wilson; Lucinda L Fulton; Jane Rogers; John Burton; Nigel P Carter; Christopher M Clee; Mark Griffiths; Matthew C Jones; Kirsten McLay; Robert W Plumb; Mark T Ross; Sarah K Sims; David L Willey; Zhu Chen; Hua Han; Le Kang; Martin Godbout; John C Wallenburg; Paul L'Archevêque; Guy Bellemare; Koji Saeki; Hongguang Wang; Daochang An; Hongbo Fu; Qing Li; Zhen Wang; Renwu Wang; Arthur L Holden; Lisa D Brooks; Jean E McEwen; Mark S Guyer; Vivian Ota Wang; Jane L Peterson; Michael Shi; Jack Spiegel; Lawrence M Sung; Lynn F Zacharia; Francis S Collins; Karen Kennedy; Ruth Jamieson; John Stewart
A second generation human haplotype map of over 3.1 million SNPs.
Nature 2007;449(7164):851-61.
2007: Anand Swaroop; Kari E H Branham; Wei Chen; Goncalo Abecasis
Genetic susceptibility to age-related macular degeneration: a paradigm for dissecting complex disease traits.
Human molecular genetics 2007;16 Spec No. 2():R174-82.
2007: Atsuhiro Kanda; Wei Chen; Mohammad I Othman; Kari E H Branham; Matthew Brooks; Ritu Khanna; Shirley He; Robert H Lyons Jr; Goncalo Abecasis; Anand Swaroop
A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(41):16227-32.
2007: Anna Dixon; Liming Liang; Miriam F Moffatt; Wei Chen; Simon Heath; Kenny C C Wong; Jenny Taylor; Edward Burnett; Ivo Gut; Martin Farrall; G Mark Lathrop; Goncalo Abecasis; William O C M Cookson
A genome-wide association study of global gene expression.
Nature genetics 2007;39(10):1202-7.
2007: Teri A Manolio; Laura Lyman Rodriguez; Lisa Brooks; Goncalo Abecasis; Dennis G Ballinger; Mark J Daly; Peter Donnelly; Stephen Faraone; Kelly A Frazer; Stacey Gabriel; Pablo Gejman; Alan Guttmacher; Emily L Harris; Thomas R Insel; John R Kelsoe; Eric Lander; Norma McCowin; Matthew D Mailman; Elizabeth G Nabel; James Ostell; Elizabeth Pugh; Stephen T Sherry; Patrick F Sullivan; John F Thompson; James Warram; David Wholley; Patrice M Milos; Francis S Collins
New models of collaboration in genome-wide association studies: the Genetic Association Information Network.
Nature genetics 2007;39(9):1045-51.
2007: Miriam F Moffatt; Michael Kabesch; Liming Liang; Anna Dixon; David Strachan; Simon Heath; Martin Depner; Andrea Von Berg; Albrecht Bufe; Ernst Rietschel; Andrea Heinzmann; Burkard Simma; Thomas Frischer; Saffron A G Willis-Owen; Kenny C C Wong; Thomas Illig; Christian Vogelberg; Stephan K Weiland; Erika von Mutius; Goncalo Abecasis; Martin Farrall; Ivo Gut; G Mark Lathrop; William O C M Cookson
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma.
Nature 2007;448(7152):470-3.
2007: ANGELO SCUTERI; serena Sanna; Wei-Min Chen; Manuela Uda; Giuseppe Albai; James Strait; Samer S Najjar; Ramaiah Nagaraja; Marco Orrú; Gianluca Usala; Mariano Dei; Sandra Lai; Andrea Maschio; Fabio Busonero; Antonella Mulas; Georg Benedikt Ehret; Ashley A Fink; Alan B Weder; Richard S Cooper; Pilar Galan; Aravinda Chakravarti; David Schlessinger; Antonio Cao; Edward Lakatta; Goncalo Abecasis
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.
PLoS genetics 2007;3(7):e115.
2007: Liming Liang; Sebastian K Zoellner ; Goncalo Abecasis
GENOME: a rapid coalescent-based whole genome simulator.
Bioinformatics (Oxford, England) 2007;23(12):1565-7.
2007: Ewan Birney; John A Stamatoyannopoulos; Anindya Dutta; Roderic Guigó; Thomas Gingeras; Elliott H Margulies; Zhiping Weng; Michael Snyder; Emmanouil T Dermitzakis; Robert E Thurman; Michael S Kuehn; Christopher M Taylor; Shane Neph; Christoph M Koch; Saurabh Asthana; Ankit Malhotra; Ivan Adzhubei; Jason A Greenbaum; Robert M Andrews; Paul Flicek; Patrick J Boyle; Hua Cao; Nigel P Carter; Gayle K Clelland; Sean Davis; Nathan Day; Pawandeep Dhami; Shane C Dillon; Michael O Dorschner; Heike Fiegler; Paul G Giresi; Jeff Goldy; Michael Hawrylycz; Andrew Haydock; Richard Humbert; Keith D James; Brett E Johnson; Ericka M Johnson; Tristan T Frum; Elizabeth R Rosenzweig; Neerja Karnani; Kirsten Lee; Gregory C Lefebvre; Patrick A Navas; Fidencio Neri; Stephen C J Parker; Peter J Sabo; Richard Sandstrom; Anthony Shafer; David Vetrie; Molly Weaver; Sarah Wilcox; Man Yu; Francis S Collins; Job Dekker; Jason Dillon Lieb; Thomas D Tullius; Gregory E Crawford; Shamil Sunyaev; William S Noble; Ian Dunham; France Denoeud; Alexandre Reymond; Philipp Kapranov; Joel Rozowsky; Deyou Zheng; Robert Castelo; Adam Frankish; Jennifer Harrow; Srinka Ghosh; Albin Sandelin; Ivo L Hofacker; Robert Baertsch; Damian Keefe; Sujit Dike; Jill Cheng; Heather A. Hirsch; Edward A Sekinger; Julien Lagarde; Josep F Abril; Atif Shahab; Christoph Flamm; Claudia Fried; Jorg Hackermuller; Jana Hertel; Manja Lindemeyer; Kristin Missal; Andrea Tanzer; Stefan Washietl; Jan Korbel; Olof Emanuelsson; Jakob S Pedersen; Nancy Holroyd; Ruth Taylor; David Swarbreck; Nicholas Matthews; Mark C Dickson; Daryl J Thomas; Matthew T Weirauch; James Gilbert; Jorg Drenkow; Ian Bell; XiaoDong Zhao; K G Srinivasan; Wing-Kin Sung; Hong Sain Ooi; Kuo Ping Chiu; Sylvain Foissac; Tyler Alioto; Michael Brent; Lior Pachter; Michael L Tress; Alfonso Valencia; Siew Woh Choo; Chiou Yu Choo; Catherine Ucla; Caroline Manzano; Carine Wyss; Evelyn Cheung; Taane G Clark; James B Brown; Madhavan Ganesh; Sandeep Patel; Hari Tammana; Jacqueline Chrast; Charlotte N Henrichsen; Chikatoshi Kai; Jun Kawai; Ugrappa Nagalakshmi; Jiaqian Wu; Zheng Lian; Jin Lian; Peter Newburger; Xueqing Zhang; Peter Bickel; John S Mattick; piero carninci; Yoshihide Hayashizaki; Sherman Weissman; Tim Hubbard; Richard Myers; Jane Rogers; Peter F Stadler; Todd M Lowe; Chia-Lin Wei; Yijun Ruan; Kevin Struhl; Mark Gerstein; Stylianos Antonarakis; Yutao Fu; Eric Green; Ulaş Karaöz; Adam Siepel; James TAYLOR; Laura A Liefer; Kris A Wetterstrand; Peter J Good; Elise A Feingold; Mark S Guyer; Gregory Cooper; George Asimenos; Colin N Dewey; Minmei Hou; Sergey Nikolaev; Juan I Montoya-Burgos; Ari Löytynoja; Simon Whelan; Fabio Pardi; Tim Massingham; Haiyan Huang; Nancy R Zhang; Ian Holmes; James C Mullikin; Abel Ureta-Vidal; Benedict Paten; Michael Seringhaus; Deanna Church; Kate Rosenbloom; W James Kent; Eric A Stone; Serafim Batzoglou; Nick Goldman; Ross C Hardison; David Haussler; Webb Miller; Arend Sidow; Nathan D Trinklein; Zhengdong D Zhang; Leah Barrera; Rhona Stuart; David C King; Adam Ameur; Stefan Enroth; Mark C Bieda; Jonghwan Kim; Akshay A Bhinge; Nan Jiang; Jun Liu; Fei Yao; Vinsensius B Vega; Charlie W H Lee; Patrick Ng; Atif Shahab; Annie Yang; Zarmik Moqtaderi; Zhou Zhu; Xiaoqin Xu; Sharon Squazzo; Matthew J Oberley; David Inman; Michael A Singer; Richmond Todd; Kyle J Munn; Alvaro Rada-Iglesias; Ola Wallerman; Jan Komorowski; Joanna C Fowler; Phillippe Couttet; Alexander W Bruce; Oliver M Dovey; Peter D Ellis; Cordelia F Langford; David A Nix; Ghia Euskirchen; Stephen Hartman; Alexander E Urban; Peter Kraus; Sara Van Calcar; Nate Heintzman; Tae Hoon Kim; Kun Wang; Chunxu Qu; Gary Hon; Rosa Luna; Christopher K Glass; M Geoff Rosenfeld; Shelley Force Aldred; Sara J Cooper; Anason Halees; Jane M Lin; Hennady P Shulha; Xiaoling Zhang; Mousheng Xu; Jaafar N S Haidar; Yong Yu; Yijun Ruan; Vishwanath R Iyer; Roland D Green; Claes Wadelius; Peggy J Farnham; Bing Ren; Rachel A Harte; Angie S Hinrichs; Heather Trumbower; Hiram Clawson; Jennifer Hillman-Jackson; Ann S Zweig; Kayla Smith; Archana Thakkapallayil; Galt Barber; Robert M Kuhn; Donna Karolchik; Lluis Armengol; Christine P Bird; Paul I W de Bakker; Andrew D Kern; Nuria Lopez-Bigas; Joel D Martin; Barbara E Stranger; Abigail Woodroffe; Eugene Davydov; Antigone Dimas; Eduardo Eyras; Ingileif B Hallgrímsdóttir; Julian Huppert; Michael C Zody; Goncalo Abecasis; Xavier Estivill; Gerard G Bouffard; Xiaobin Guan; Nancy F Hansen; Jacquelyn R Idol; Valerie V B Maduro; Baishali Maskeri; Jennifer C McDowell; Morgan Park; Pamela J Thomas; Alice C Young; Robert W Blakesley; Donna M Muzny; Erica Sodergren; David A Wheeler; Kim C Worley; Huaiyang Jiang; George Weinstock; Richard A Gibbs; Tina Graves; Robert Fulton; Elaine R Mardis; Richard K Wilson; Michele Clamp; James Cuff; Sante Gnerre; David B Jaffe; Jean L Chang; Kerstin Lindblad-Toh; Eric S Lander; Maxim Koriabine; Mikhail Nefedov; Kazutoyo Osoegawa; Yuko Yoshinaga; Baoli Zhu; Pieter J de Jong
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.
Nature 2007;447(7146):799-816.
2007: STEPHEN CHANOCK; Teri Manolio; Michael Boehnke; Eric Boerwinkle; David J Hunter; Gilles Thomas; Joel N Hirschhorn; Goncalo Abecasis; David Altshuler; Joan E Bailey-Wilson; Lisa D Brooks; Lon R Cardon; Mark J Daly; Peter Donnelly; Joseph Fraumeni; Nelson B Freimer; Daniela S Gerhard; Chris Gunter; Alan E Guttmacher; Mark S Guyer; Emily L Harris; Josephine Hoh; Robert Hoover; C Augustine Kong; Kathleen Ries Merikangas; Cynthia C Morton; Lyle Palmer; Elizabeth G Phimister; John P Rice; Jerry Roberts; Charles Rotimi; Margaret A Tucker; Kyle J Vogan; Sholom Wacholder; Ellen M Wijsman; Deborah M Winn; Francis S Collins
Replicating genotype-phenotype associations.
Nature 2007;447(7145):655-60.
2007: Laura J Scott; Karen L Mohlke; Lori L Bonnycastle; Cristen J Willer; Yun Li; William L Duren; Michael R Erdos; Heather M Stringham; Peter S Chines; Anne U Jackson; Ludmila Prokunina-Olsson; Chia-Jen Ding; Amy J Swift; Narisu Narisu; Tianle Hu; Randall Pruim; Rui Xiao; Xiao-Yi Li; Karen N Conneely; Nancy L Riebow; Andrew G Sprau; Maurine Tong; Peggy P White; Kurt N Hetrick; Michael W Barnhart; Craig W Bark; Janet L Goldstein; Lee Watkins; Fang Xiang; Jouko Saramies; Thomas A Buchanan; Richard Watanabe; Timo T Valle; Leena Kinnunen; Goncalo Abecasis; Elizabeth W Pugh; Kimberly F Doheny; Richard N Bergman; Jaakko Tuomilehto; Francis S Collins; Michael Boehnke
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
Science (New York, N.Y.) 2007;316(5829):1341-5.
2007: Goncalo Abecasis; Paul K H Tam; Carlos Bustamante; Elaine A Ostrander; Stephen W Scherer; STEPHEN CHANOCK; Pui-Yan Kwok; Anthony J Brookes
Human Genome Variation 2006: emerging views on structural variation and large-scale SNP analysis.
Nature genetics 2007;39(2):153-5.
2007: Ruby Hsu; Abigail Woodroffe; Wen-Sung Lai; Melloni N Cook; Jun Mukai; Jonathan P Dunning; Douglas J Swanson; J Louw Roos; Goncalo Abecasis; Maria Karayiorgou; Joseph A Gogos
Nogo Receptor 1 (RTN4R) as a candidate gene for schizophrenia: analysis using human and mouse genetic approaches.
PloS one 2007;2(11):e1234.
2006: Mingyao Li; Pelin Atmaca Sonmez; Mohammad I Othman; Kari E H Branham; Ritu Khanna; Michael S Wade; Yun Li; Liming Liang; Sepideh Zareparsi; Anand Swaroop; Goncalo Abecasis
CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration.
Nature genetics 2006;38(9):1049-54.
2006: Joshua T Burdick; Wei-Min Chen; Goncalo Abecasis; Vivian G Cheung
In silico method for inferring genotypes in pedigrees.
Nature genetics 2006;38(9):1002-4.
2006: Wei-Min Chen; Goncalo Abecasis
Estimating the power of variance component linkage analysis in large pedigrees.
Genetic epidemiology 2006;30(6):471-84.
2006: Giuseppe Pilia; Wei-Min Chen; ANGELO SCUTERI; Marco Orrú; Giuseppe Albai; Mariano Dei; Sandra Lai; Gianluca Usala; Monica Lai; Paola Loi; Cinzia Mameli; Loredana Vacca; Manila Deiana; Nazario Olla; Marco Masala; Antonio Cao; Samer S Najjar; Antonio Terracciano; Timur Nedorezov; Alexei Sharov; Alan B Zonderman; Goncalo Abecasis; Paul Costa; Edward G Lakatta; David Schlessinger
Heritability of cardiovascular and personality traits in 6,148 Sardinians.
PLoS genetics 2006;2(8):e132.
2006: Mingyao Li; Michael Boehnke; Goncalo Abecasis; Peter X-K Song
Quantitative trait linkage analysis using Gaussian copulas.
Genetics 2006;173(4):2317-27.
2006: Tasha E Fingerlin; Goncalo Abecasis; Michael Boehnke
Using sex-averaged genetic maps in multipoint linkage analysis when identity-by-descent status is incompletely known.
Genetic epidemiology 2006;30(5):384-96.
2006: Janis E Wigginton; Goncalo Abecasis
An evaluation of the replicate pool method: quick estimation of genome-wide linkage peak p-values.
Genetic epidemiology 2006;30(4):320-32.
2006: Rajan P Nair; Philip Stuart; Ioana Nistor; Ravi Hiremagalore; Nicholas V C Chia; Stefan Jenisch; Michael Weichenthal; Goncalo Abecasis; Henry W Lim; Enno Christophers; John J Voorhees; James T Elder
Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene.
American journal of human genetics 2006;78(5):827-51.
2006: Mingyao Li; Michael Boehnke; Goncalo Abecasis
Efficient study designs for test of genetic association using sibship data and unrelated cases and controls.
American journal of human genetics 2006;78(5):778-92.
2006: Jonathan Marchini; David Cutler; Nick Patterson; Matthew Stephens; Eleazar Eskin; Eran Halperin; Shin Lin; Zhaohui S Qin; Heather M Munro; Goncalo Abecasis; Peter Donnelly
A comparison of phasing algorithms for trios and unrelated individuals.
American journal of human genetics 2006;78(3):437-50.
2006: Andrew D Skol; Laura J Scott; Goncalo Abecasis; Michael Boehnke
Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies.
Nature genetics 2006;38(2):209-13.
2006: Zhaohui S Qin; Shyam Gopalakrishnan; Goncalo Abecasis
An efficient comprehensive search algorithm for tagSNP selection using linkage disequilibrium criteria.
Bioinformatics (Oxford, England) 2006;22(2):220-5.
2006: Philip Stuart; Rajan P Nair; Goncalo Abecasis; Ioana Nistor; Ravi Hiremagalore; Nicholas V C Chia; Zhaohui S Qin; R A Thompson; Stefan Jenisch; Michael Weichenthal; J Janiga; Henry W Lim; Enno Christophers; John J Voorhees; James T Elder
Analysis of RUNX1 binding site and RAPTOR polymorphisms in psoriasis: no evidence for association despite adequate power and evidence for linkage.
Journal of medical genetics 2006;43(1):12-7.
2005: Goncalo Abecasis; Janis E Wigginton
Handling marker-marker linkage disequilibrium: pedigree analysis with clustered markers.
American journal of human genetics 2005;77(5):754-67.
2005: Albert Vernon Smith; Daryl J Thomas; Heather M Munro; Goncalo Abecasis
Sequence features in regions of weak and strong linkage disequilibrium.
Genome research 2005;15(11):1519-34.
2005: Janis E Wigginton; Goncalo Abecasis
PEDSTATS: descriptive statistics, graphics and quality assessment for gene mapping data.
Bioinformatics (Oxford, England) 2005;21(16):3445-7.
2005: Ioana Nistor; Rajan P Nair; Philip Stuart; Ravi Hiremagalore; Rachel A Thompson; Stefan Jenisch; Michael Weichenthal; Goncalo Abecasis; Zhaohui S Qin; Enno Christophers; Henry W Lim; John J Voorhees; James T Elder
Protein tyrosine phosphatase gene PTPN22 polymorphism in psoriasis: lack of evidence for association.
The Journal of investigative dermatology 2005;125(2):395-6.
2005: Sheila A Fisher; Goncalo Abecasis; Beverly M Yashar; Sepideh Zareparsi; Anand Swaroop; Sudha K Iyengar; Barbara E K Klein; Ronald Klein; Kristine E Lee; Jacek Majewski; Dennis W Schultz; Michael L Klein; Johanna M Seddon; Susan L Santangelo; Daniel E Weeks; Yvette P Conley; Tammy S Mah; Silke Schmidt; Jonathan L Haines; Margaret Pericak-Vance; Michael B Gorin; Heidi Schulz; Fabio Pardi; Cathryn M Lewis; Bernhard H F Weber
Meta-analysis of genome scans of age-related macular degeneration.
Human molecular genetics 2005;14(15):2257-64.
2005: Sepideh Zareparsi; Kari E H Branham; Mingyao Li; Sapna Shah; Robert J. Klein; Jurg Ott; Josephine Hoh; Goncalo Abecasis; Anand Swaroop
Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration.
American journal of human genetics 2005;77(1):149-53.
2005: Mingyao Li; Michael Boehnke; Goncalo Abecasis
Joint modeling of linkage and association: identifying SNPs responsible for a linkage signal.
American journal of human genetics 2005;76(6):934-49.
2005: Sepideh Zareparsi; Monika Buraczynska; Kari E H Branham; Sapna Shah; Donna Eng; Mingyao Li; Hemant Pawar; Beverly M Yashar; Sayoko E Moroi; Paul R Lichter; Howard R Petty; Julia E Richards; Goncalo Abecasis; Victor M Elner; Anand Swaroop
Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration.
Human molecular genetics 2005;14(11):1449-55.
2005: Janis E Wigginton; David J Cutler; Goncalo Abecasis
A note on exact tests of Hardy-Weinberg equilibrium.
American journal of human genetics 2005;76(5):887-93.
2005: Goncalo Abecasis; Debashis Ghosh; Thomas E Nichols
Linkage disequilibrium: ancient history drives the new genetics.
Human heredity 2005;59(2):118-24.
2004: Matthew W Nash; Patricia Huezo-Diaz; Richard J Williamson; Abram Sterne; Shaun Purcell; Farzana Hoda; Stacey Cherny; Goncalo Abecasis; Martin Prince; Jeffrey A Gray; David Ball; Philip Asherson; Anthony Mann; David Goldberg; Peter McGuffin; Anne Farmer; Robert Plomin; Ian W Craig; Pak C Sham
Genome-wide linkage analysis of a composite index of neuroticism and mood-related scales in extreme selected sibships.
Human molecular genetics 2004;13(19):2173-82.
2004: Goncalo Abecasis; Nancy Cox; Mark J Daly; Leonid Kruglyak; Nan Laird; Kyriacos Markianos; Nick Patterson
No bias in linkage analysis.
American journal of human genetics 2004;75(4):722-3; author reply 723-7.
2004: Goncalo Abecasis; Beverly M Yashar; Yu Zhao; Noor M Ghiasvand; Sepideh Zareparsi; Kari E H Branham; Adam C Reddick; Edward H Trager; Shigeo Yoshida; John Bahling; Elena Filippova; Susan G Elner; Mark W Johnson; Andrew K Vine; Paul Sieving; Samuel G Jacobson; Julia E Richards; Anand Swaroop
Age-related macular degeneration: a high-resolution genome scan for susceptibility loci in a population enriched for late-stage disease.
American journal of human genetics 2004;74(3):482-94.
2004: Tasha E Fingerlin; Michael Boehnke; Goncalo Abecasis
Increasing the power and efficiency of disease-marker case-control association studies through use of allele-sharing information.
American journal of human genetics 2004;74(3):432-43.
2004: Goncalo Abecasis; Rachel A Burt; Diana Hall; Sylvia Bochum; Kimberly F Doheny; S Laura Lundy; Marie Torrington; J Louw Roos; Joseph A Gogos; Maria Karayiorgou
Genomewide scan in families with schizophrenia from the founder population of Afrikaners reveals evidence for linkage and uniparental disomy on chromosome 1.
American journal of human genetics 2004;74(3):403-17.
2004: Maria Karayiorgou; Marie Torrington; Goncalo Abecasis; Herman Pretorius; Brian Robertson; Sean Kaliski; Stephen Lay; Christina Sobin; Natalie Möller; S Laura Lundy; Maude L Blundell; Joseph A Gogos; J Louw Roos
Phenotypic characterization and genealogical tracing in an Afrikaner schizophrenia database.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;124B(1):20-8.
2003: Maxine Allen; Andrea Heinzmann; Emiko Noguchi; Goncalo Abecasis; John Broxholme; Chris P Ponting; Sumit Bhattacharyya; Jon Tinsley; Youming Zhang; Richard Holt; E Yvonne Jones; Nicholas J Lench; Alisoun Carey; Helene Jones; Nicholas J Dickens; Claire Dimon; Rosie Nicholls; Crystal Baker; Luzheng Xue; Elizabeth Townsend; Michael Kabesch; Stephan K Weiland; David Carr; Erika von Mutius; Ian M Adcock; Peter J Barnes; G Mark Lathrop; Mark Edwards; Miriam F Moffatt; William O C M Cookson
Positional cloning of a novel gene influencing asthma from chromosome 2q14.
Nature genetics 2003;35(3):258-63.
2003: Youming Zhang; Nicholas I Leaves; Gavin G Anderson; Chris P Ponting; John Broxholme; Richard Holt; Pauline Edser; Sumit Bhattacharyya; Andy Dunham; Ian M Adcock; Louise Pulleyn; Peter J Barnes; John I Harper; Goncalo Abecasis; Lon Cardon; Melanie White; John Burton; Lucy Matthews; Richard Mott; Mark Ross; Roger Cox; Miriam F Moffatt; William O C M Cookson
Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma.
Nature genetics 2003;34(2):181-6.
2003: Lon R Cardon; Goncalo Abecasis
Using haplotype blocks to map human complex trait loci.
Trends in genetics : TIG 2003;19(3):135-40.
2003: M S Phillips; R Lawrence; R Sachidanandam; A P Morris; D J Balding; M A Donaldson; J F Studebaker; W M Ankener; S V Alfisi; F-S Kuo; A L Camisa; V Pazorov; K E Scott; B J Carey; J Faith; G Katari; H A Bhatti; J M Cyr; V Derohannessian; C Elosua; A M Forman; N M Grecco; C R Hock; J M Kuebler; J A Lathrop; M A Mockler; E P Nachtman; S L Restine; S A Varde; M J Hozza; C A Gelfand; J Broxholme; Goncalo Abecasis; michael Boyce-jacino; L R Cardon
Chromosome-wide distribution of haplotype blocks and the role of recombination hot spots.
Nature genetics 2003;33(3):382-7.
2003: Maurice Zeegers; John P Rice; Frühling Rijsdijk; Goncalo Abecasis; Pak C Sham
Regression-based sib pair linkage analysis for binary traits.
Human heredity 2003;55(2-3):125-31.
2002: Hui Liu; Goncalo Abecasis; Simon Heath; Alyson Knowles; Sandra Demars; Ying-Jiun Chen; J Louw Roos; Judy Rapoport; Joseph A Gogos; Maria Karayiorgou
Genetic variation in the 22q11 locus and susceptibility to schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16859-64.
2002: Pak C Sham; Shaun Purcell; Stacey Cherny; Goncalo Abecasis
Powerful regression-based quantitative-trait linkage analysis of general pedigrees.
American journal of human genetics 2002;71(2):238-53.
2002: Elisabeth Dawson; Goncalo Abecasis; Suzannah Bumpstead; Yuan Chen; Sarah Hunt; David M Beare; Jagjit Pabial; Thomas Dibling; Emma Tinsley; Susan Kirby; David Carter; Marianna Papaspyridonos; Simon Livingstone; Rocky Ganske; Elin Lõhmussaar; Jana Zernant; Neeme Tõnisson; Maido Remm; Reedik Mägi; Tarmo Puurand; Jaak Vilo; Ants Kurg; Kate Rice; Panos Deloukas; Richard Mott; Andres Metspalu; David R Bentley; Lon R Cardon; Carl Bruder
A first-generation linkage disequilibrium map of human chromosome 22.
Nature 2002;418(6897):544-8.
2002: W Zhang; ANDREW COLLINS; Goncalo Abecasis; L R Cardon; Newton E Morton
Mapping quantitative effects of oligogenes by allelic association.
Annals of human genetics 2002;66(Pt 3):211-21.
2002: Gavin G Anderson; Nicholas I Leaves; Sumit Bhattacharyya; Youming Zhang; Valerie Walshe; John Broxholme; Goncalo Abecasis; Elaine Levy; Michael Zimmer; Roger Cox; William O C M Cookson
Positive association to IgE levels and a physical map of the 13q14 atopy locus.
European journal of human genetics : EJHG 2002;10(4):266-70.
2002: Goncalo Abecasis; Stacey Cherny; William O Cookson; Lon R Cardon
Merlin--rapid analysis of dense genetic maps using sparse gene flow trees.
Nature genetics 2002;30(1):97-101.
2001: Andrew J Walley; Stéphane Chavanas; Miriam F Moffatt; R M Esnouf; B Ubhi; R Lawrence; K Wong; Goncalo Abecasis; E Yvonne Jones; John I Harper; Alain Hovnanian; William O C M Cookson
Gene polymorphism in Netherton and common atopic disease.
Nature genetics 2001;29(2):175-8.
2001: Goncalo Abecasis; Stacey Cherny; William O C M Cookson; Lon R Cardon
GRR: graphical representation of relationship errors.
Bioinformatics (Oxford, England) 2001;17(8):742-3.
2001: Goncalo Abecasis; W O Cookson; Lon R Cardon
The power to detect linkage disequilibrium with quantitative traits in selected samples.
American journal of human genetics 2001;68(6):1463-74.
2001: Miriam F Moffatt; C Schou; Jennie A Faux; Goncalo Abecasis; Alan James; A William Musk; William O C M Cookson
Association between quantitative traits underlying asthma and the HLA-DRB1 locus in a family-based population sample.
European journal of human genetics : EJHG 2001;9(5):341-6.
2001: Colin A McKenzie; Goncalo Abecasis; Bernard Keavney; Terrence Forrester; Peter J Ratcliffe; Cécile Julier; J M Connell; Franklyn I Bennett; N McFarlane-Anderson; G Mark Lathrop; L R Cardon
Trans-ethnic fine mapping of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE).
Human molecular genetics 2001;10(10):1077-84.
2001: William O C M Cookson; B Ubhi; R Lawrence; Goncalo Abecasis; Andrew J Walley; H E Cox; R Coleman; Nicholas I Leaves; Richard C Trembath; Miriam F Moffatt; John I Harper
Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci.
Nature genetics 2001;27(4):372-3.
2001: Goncalo Abecasis; Stacey Cherny; Lon R Cardon
The impact of genotyping error on family-based analysis of quantitative traits.
European journal of human genetics : EJHG 2001;9(2):130-4.
2001: Goncalo Abecasis; Lon R Cardon; William O C M Cookson; P C Sham; Stacey Cherny
Association analysis in a variance components framework.
Genetic epidemiology 2001;21 Suppl 1():S341-6.
2001: Stacey Cherny; Goncalo Abecasis; William O C M Cookson; P C Sham; Lon R Cardon
The effect of genotype and pedigree error on linkage analysis: analysis of three asthma genome scans.
Genetic epidemiology 2001;21 Suppl 1():S117-22.
2001: Goncalo Abecasis; E Noguchi; Andrea Heinzmann; James A Traherne; Sumit Bhattacharyya; Nicholas I Leaves; Gavin G Anderson; Youming Zhang; Nicholas J Lench; Alisoun Carey; Lon R Cardon; Miriam F Moffatt; William O C M Cookson
Extent and distribution of linkage disequilibrium in three genomic regions.
American journal of human genetics 2001;68(1):191-197.
2000: Goncalo Abecasis; W O Cookson; Lon R Cardon
Pedigree tests of transmission disequilibrium.
European journal of human genetics : EJHG 2000;8(7):545-51.
2000: Lon R Cardon; Goncalo Abecasis
Some properties of a variance components model for fine-mapping quantitative trait loci.
Behavior genetics 2000;30(3):235-43.
2000: Miriam F Moffatt; James A Traherne; Goncalo Abecasis; William O C M Cookson
Single nucleotide polymorphism and linkage disequilibrium within the TCR alpha/delta locus.
Human molecular genetics 2000;9(7):1011-9.
2000: Goncalo Abecasis; William O C M Cookson
GOLD--graphical overview of linkage disequilibrium.
Bioinformatics (Oxford, England) 2000;16(2):182-3.
2000: Goncalo Abecasis; Lon R Cardon; William O C M Cookson
A general test of association for quantitative traits in nuclear families.
American journal of human genetics 2000;66(1):279-92.