Henry Furneaux

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Salzman David W; Shubert-Coleman Jonathan; Furneaux Henry
P68 RNA helicase unwinds the human let-7 microRNA precursor duplex and is required for let-7-directed silencing of gene expression.
Chakrabarty Anindita; Tranguch Susanne; Daikoku Takiko; Jensen Kevin; Furneaux Henry; Dey Sudhansu K
MicroRNA regulation of cyclooxygenase-2 during embryo implantation.
Adams Brian D; Furneaux Henry; White Bruce A
The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines.

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2007: Salzman David W; Shubert-Coleman Jonathan; Furneaux Henry
P68 RNA helicase unwinds the human let-7 microRNA precursor duplex and is required for let-7-directed silencing of gene expression.
The Journal of biological chemistry 2007;282(45):32773-9.
2007: Chakrabarty Anindita; Tranguch Susanne; Daikoku Takiko; Jensen Kevin; Furneaux Henry; Dey Sudhansu K
MicroRNA regulation of cyclooxygenase-2 during embryo implantation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(38):15144-9.
2007: Adams Brian D; Furneaux Henry; White Bruce A
The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines.
Molecular endocrinology (Baltimore, Md.) 2007;21(5):1132-47.
2007: Abdelmohsen Kotb; Pullmann Rudolf; Lal Ashish; Kim Hyeon Ho; Galban Stefanie; Yang Xiaoling; Blethrow Justin D; Walker Mark; Shubert Jonathan; Gillespie David A; Furneaux Henry; Gorospe Myriam
Phosphorylation of HuR by Chk2 regulates SIRT1 expression.
Molecular cell 2007;25(4):543-57.
2005: Erkinheimo Tiina-Liisa; Sivula Anna; Lassus Heini; Heinonen Mira; Furneaux Henry; Haglund Caj; Butzow Ralf; Ristimäki Ari
Cytoplasmic HuR expression correlates with epithelial cancer cell but not with stromal cell cyclooxygenase-2 expression in mucinous ovarian carcinoma.
Gynecologic oncology 2005;99(1):14-9.
2005: Heinonen Mira; Bono Petri; Narko Kirsi; Chang Sung-Hee; Lundin Johan; Joensuu Heikki; Furneaux Henry; Hla Timothy; Haglund Caj; Ristimäki Ari
Cytoplasmic HuR expression is a prognostic factor in invasive ductal breast carcinoma.
Cancer research 2005;65(6):2157-61.
2004: Smith Catherine L; Afroz Rownak; Bassell Gary J; Furneaux Henry M; Perrone-Bizzozero Nora I; Burry Richard W
GAP-43 mRNA in growth cones is associated with HuD and ribosomes.
Journal of neurobiology 2004;61(2):222-35.
2004: Chae Sung-Suk; Paik Ji-Hye; Furneaux Henry; Hla Timothy
Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference.
The Journal of clinical investigation 2004;114(8):1082-9.
2003: Erkinheimo Tiina-Liisa; Lassus Heini; Sivula Anna; Sengupta Sibani; Furneaux Henry; Hla Timothy; Haglund Caj; Butzow Ralf; Ristimäki Ari
Cytoplasmic HuR expression correlates with poor outcome and with cyclooxygenase 2 expression in serous ovarian carcinoma.
Cancer research 2003;63(22):7591-4.
2003: Cuadrado Ana; Navarro-Yubero Cristina; Furneaux Henry; Muñoz Alberto
Neuronal HuD gene encoding a mRNA stability regulator is transcriptionally repressed by thyroid hormone.
Journal of neurochemistry 2003;86(3):763-73.
2003: Sengupta Sibani; Jang Byeong-Churl; Wu Ming-Tao; Paik Ji-Hye; Furneaux Henry; Hla Timothy
The RNA-binding protein HuR regulates the expression of cyclooxygenase-2.
The Journal of biological chemistry 2003;278(27):25227-33.
2003: Bogdan Carol A; Alexander Alice A; Gorny Miroslaw K; Matute Reynaldo; Marjanovic Nada; Zolla-Pazner Susan; Walden Paul D; Furneaux Henry M; Sidhu Gurdip S; Jacobson Daniel R
Chronic lymphocytic leukemia with prostate infiltration mediated by specific clonal membrane-bound IgM.
Cancer research 2003;63(9):2067-71.
2003: Kloss Stephan; Furneaux Henry; Mülsch Alexander
Post-transcriptional regulation of soluble guanylyl cyclase expression in rat aorta.
The Journal of biological chemistry 2003;278(4):2377-83.
2003: Giles Keith M; Daly John M; Beveridge Dianne J; Thomson Andrew M; Voon Dominic C; Furneaux Henry M; Jazayeri Jalal A; Leedman Peter J
The 3'-untranslated region of p21WAF1 mRNA is a composite cis-acting sequence bound by RNA-binding proteins from breast cancer cells, including HuR and poly(C)-binding protein.
The Journal of biological chemistry 2003;278(5):2937-46.
2002: Yeap Bu B; Voon Dominic C; Vivian Julian P; McCulloch Ross K; Thomson Andrew M; Giles Keith M; Czyzyk-Krzeska Maria F; Furneaux Henry; Wilce Matthew C J; Wilce Jackie A; Leedman Peter J
Novel binding of HuR and poly(C)-binding protein to a conserved UC-rich motif within the 3'-untranslated region of the androgen receptor messenger RNA.
The Journal of biological chemistry 2002;277(30):27183-92.
2002: Cuadrado Ana; Navarro-Yubero Cristina; Furneaux Henry; Kinter Jochen; Sonderegger Peter; Muñoz Alberto
HuD binds to three AU-rich sequences in the 3'-UTR of neuroserpin mRNA and promotes the accumulation of neuroserpin mRNA and protein.
Nucleic acids research 2002;30(10):2202-11.
2001: Di Marco S; Hel Z; Lachance C; Furneaux H; Radzioch D
Polymorphism in the 3'-untranslated region of TNFalpha mRNA impairs binding of the post-transcriptional regulatory protein HuR to TNFalpha mRNA.
Nucleic acids research 2001;29(4):863-71.
2000: Mobarak C D; Anderson K D; Morin M; Beckel-Mitchener A; Rogers S L; Furneaux H; King P; Perrone-Bizzozero N I
The RNA-binding protein HuD is required for GAP-43 mRNA stability, GAP-43 gene expression, and PKC-dependent neurite outgrowth in PC12 cells.
Molecular biology of the cell 2000;11(9):3191-203.
2000: Anderson K D; Morin M A; Beckel-Mitchener A; Mobarak C D; Neve R L; Furneaux H M; Burry R; Perrone-Bizzozero N I
Overexpression of HuD, but not of its truncated form HuD I+II, promotes GAP-43 gene expression and neurite outgrowth in PC12 cells in the absence of nerve growth factor.
Journal of neurochemistry 2000;75(3):1103-14.
2000: Rodriguez-Pascual F; Hausding M; Ihrig-Biedert I; Furneaux H; Levy A P; Förstermann U; Kleinert H
Complex contribution of the 3'-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR.
The Journal of biological chemistry 2000;275(34):26040-9.
2000: Zhao Z; Chang F C; Furneaux H M
The identification of an endonuclease that cleaves within an HuR binding site in mRNA.
Nucleic acids research 2000;28(14):2695-701.
2000: Wang W; Caldwell M C; Lin S; Furneaux H; Gorospe M
HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation.
The EMBO journal 2000;19(10):2340-50.
2000: Wang W; Furneaux H; Cheng H; Caldwell M C; Hutter D; Liu Y; Holbrook N; Gorospe M
HuR regulates p21 mRNA stabilization by UV light.
Molecular and cellular biology 2000;20(3):760-9.
2000: Haeussler J; Haeusler J; Striebel A M; Assum G; Vogel W; Furneaux H; Krone W
Tumor antigen HuR binds specifically to one of five protein-binding segments in the 3'-untranslated region of the neurofibromin messenger RNA.
Biochemical and biophysical research communications 2000;267(3):726-32.
1999: Aranda-Abreu G E; Behar L; Chung S; Furneaux H; Ginzburg I
Embryonic lethal abnormal vision-like RNA-binding proteins regulate neurite outgrowth and tau expression in PC12 cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(16):6907-17.
1999: Sokolowski M; Furneaux H; Schwartz S
The inhibitory activity of the AU-rich RNA element in the human papillomavirus type 1 late 3' untranslated region correlates with its affinity for the elav-like HuR protein.
Journal of virology 1999;73(2):1080-91.
1998: Nabors L B; Furneaux H M; King P H
HuR, a novel target of anti-Hu antibodies, is expressed in non-neural tissues.
Journal of neuroimmunology 1998;92(1-2):152-9.
1998: Joseph B; Orlian M; Furneaux H
p21(waf1) mRNA contains a conserved element in its 3'-untranslated region that is bound by the Elav-like mRNA-stabilizing proteins.
The Journal of biological chemistry 1998;273(32):20511-6.
1998: Joseph B; Furneaux H
Complementary DNA libraries and neurological disease.
Archives of neurology 1998;55(6):785-8.
1998: Levy N S; Chung S; Furneaux H; Levy A P
Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR.
The Journal of biological chemistry 1998;273(11):6417-23.
1997: Ma W J; Chung S; Furneaux H
The Elav-like proteins bind to AU-rich elements and to the poly(A) tail of mRNA.
Nucleic acids research 1997;25(18):3564-9.
1997: Chung S; Eckrich M; Perrone-Bizzozero N; Kohn D T; Furneaux H
The Elav-like proteins bind to a conserved regulatory element in the 3'-untranslated region of GAP-43 mRNA.
The Journal of biological chemistry 1997;272(10):6593-8.
1997: Ma W J; Furneaux H
Localization of the human HuR gene to chromosome 19p13.2.
Human genetics 1997;99(1):32-3.
1996: Chung S; Jiang L; Cheng S; Furneaux H
Purification and properties of HuD, a neuronal RNA-binding protein.
The Journal of biological chemistry 1996;271(19):11518-24.
1996: Ma W J; Cheng S; Campbell C; Wright A; Furneaux H
Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein.
The Journal of biological chemistry 1996;271(14):8144-51.
1995: Barami K; Iversen K; Furneaux H; Goldman S A
Hu protein as an early marker of neuronal phenotypic differentiation by subependymal zone cells of the adult songbird forebrain.
Journal of neurobiology 1995;28(1):82-101.
1995: Liu J; Dalmau J; Szabo A; Rosenfeld M; Huber J; Furneaux H
Paraneoplastic encephalomyelitis antigens bind to the AU-rich elements of mRNA.
Neurology 1995;45(3 Pt 1):544-50.
1994: Marusich M F; Furneaux H M; Henion P D; Weston J A
Hu neuronal proteins are expressed in proliferating neurogenic cells.
Journal of neurobiology 1994;25(2):143-55.
1994: Muresu R; Baldini A; Gress T; Posner J B; Furneaux H M; Siniscalco M
Mapping of the gene coding for a paraneoplastic encephalomyelitis antigen (HuD) to human chromosome site 1p34.
Cytogenetics and cell genetics 1994;65(3):177-8.
1994: Manley G; Wong E; Dalmau J; Elkon K; Posner J; Furneaux H
Sera from some patients with antibody-associated paraneoplastic encephalomyelitis/sensory neuronopathy recognize the Ro-52K antigen.
Journal of neuro-oncology 1994;19(2):105-12.
1993: Rosenfeld M R; Wong E; Dalmau J; Manley G; Egan D; Posner J B; Sher E; Furneaux H M
Sera from patients with Lambert-Eaton myasthenic syndrome recognize the beta-subunit of Ca2+ channel complexes.
Annals of the New York Academy of Sciences 1993;681():408-11.
1993: Rosenfeld M R; Wong E; Dalmau J; Manley G; Posner J B; Sher E; Furneaux H M
Cloning and characterization of a Lambert-Eaton myasthenic syndrome antigen.
Annals of neurology 1993;33(1):113-20.
1992: Dalmau J; Furneaux H M; Cordon-Cardo C; Posner J B
The expression of the Hu (paraneoplastic encephalomyelitis/sensory neuronopathy) antigen in human normal and tumor tissues.
The American journal of pathology 1992;141(4):881-6.
1992: Schlegel U; Rosenfeld M R; Volkenandt M; Rosenblum M; Dalmau J; Furneaux H
p53 gene mutations in primary lung tumors are conserved in brain metastases.
Journal of neuro-oncology 1992;14(2):93-100.
1992: DeAngelis L M; Wong E; Rosenblum M; Furneaux H
Epstein-Barr virus in acquired immune deficiency syndrome (AIDS) and non-AIDS primary central nervous system lymphoma.
Cancer 1992;70(6):1607-11.
1992: Gress T; Baldini A; Rocchi M; Furneaux H; Posner J B; Siniscalco M
In situ mapping of the gene coding for a leucine zipper DNA binding protein (CDR62) to 16p12-16p13.1.
Genomics 1992;13(4):1340-2.
1992: Henson J; Saffer J; Furneaux H
The transcription factor Sp1 binds to the JC virus promoter and is selectively expressed in glial cells in human brain.
Annals of neurology 1992;32(1):72-7.
1991: Henson J; Rosenblum M; Armstrong D; Furneaux H
Amplification of JC virus DNA from brain and cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy.
Neurology 1991;41(12):1967-71.
1991: Dalmau J; Furneaux H M; Rosenblum M K; Graus F; Posner J B
Detection of the anti-Hu antibody in specific regions of the nervous system and tumor from patients with paraneoplastic encephalomyelitis/sensory neuronopathy.
Neurology 1991;41(11):1757-64.
1991: Szabo A; Dalmau J; Manley G; Rosenfeld M; Wong E; Henson J; Posner J B; Furneaux H M
HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal.
Cell 1991;67(2):325-33.
1991: Darnell R B; Furneaux H M; Posner J B
Antiserum from a patient with cerebellar degeneration identifies a novel protein in Purkinje cells, cortical neurons, and neuroectodermal tumors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991;11(5):1224-30.
1991: Fathallah-Shaykh H; Wolf S; Wong E; Posner J B; Furneaux H M
Cloning of a leucine-zipper protein recognized by the sera of patients with antibody-associated paraneoplastic cerebellar degeneration.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3451-4.
1991: Luque F A; Furneaux H M; Ferziger R; Rosenblum M K; Wray S H; Schold S C; Glantz M J; Jaeckle K A; Biran H; Lesser M
Anti-Ri: an antibody associated with paraneoplastic opsoclonus and breast cancer.
Annals of neurology 1991;29(3):241-51.
1991: Siniscalco M; Oberlé I; Melis P; Alhadeff B; Murray J; Filippi G; Mattioni T; Chen Y T; Furneaux H; Old L J
Physical and genetic mapping of the CDR gene with particular reference to its position with respect to the FRAXA site.
American journal of medical genetics 1991;38(2-3):357-62.
1990: Schlegel U; Moots P L; Rosenblum M K; Thaler H T; Furneaux H M
Expression of transforming growth factor alpha in human gliomas.
Oncogene 1990;5(12):1839-42.
1990: Furneaux H F; Reich L; Posner J B
Autoantibody synthesis in the central nervous system of patients with paraneoplastic syndromes.
Neurology 1990;40(7):1085-91.
1990: Furneaux H M; Rosenblum M K; Dalmau J; Wong E; Woodruff P; Graus F; Posner J B
Selective expression of Purkinje-cell antigens in tumor tissue from patients with paraneoplastic cerebellar degeneration.
The New England journal of medicine 1990;322(26):1844-51.
1990: Dalmau J; Furneaux H M; Gralla R J; Kris M G; Posner J B
Detection of the anti-Hu antibody in the serum of patients with small cell lung cancer--a quantitative western blot analysis.
Annals of neurology 1990;27(5):544-52.
1990: Kenny M K; Schlegel U; Furneaux H; Hurwitz J
The role of human single-stranded DNA binding protein and its individual subunits in simian virus 40 DNA replication.
The Journal of biological chemistry 1990;265(13):7693-700.
1990: Pruzan R; Furneaux H; Lassota P; Hong G Y; Hurwitz J
Assemblage of the prespliceosome complex with separated fractions isolated from HeLa cells.
The Journal of biological chemistry 1990;265(5):2804-13.
1990: Posner J B; Furneaux H M
Paraneoplastic syndromes.
Research publications - Association for Research in Nervous and Mental Disease 1990;68():187-219.
1990: Pick L; Furneaux H M; Hurwitz J
Purification and characterization of wheat germ RNA ligase and associated activities.
Methods in enzymology 1990;181():480-99.
1989: Furneaux H M; Dropcho E J; Barbut D; Chen Y T; Rosenblum M K; Old L J; Posner J B
Characterization of a cDNA encoding a 34-kDa Purkinje neuron protein recognized by sera from patients with paraneoplastic cerebellar degeneration.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(8):2873-7.
1987: Freyer G A; Arenas J; Perkins K K; Furneaux H M; Pick L; Young B; Roberts R J; Hurwitz J
In vitro formation of a lariat structure containing a G2'-5'G linkage.
The Journal of biological chemistry 1987;262(9):4267-73.
1986: Pick L; Furneaux H; Hurwitz J
Purification of wheat germ RNA ligase. II. Mechanism of action of wheat germ RNA ligase.
The Journal of biological chemistry 1986;261(15):6694-704.
1986: Perkins K K; Furneaux H M; Hurwitz J
RNA splicing products formed with isolated fractions from HeLa cells are associated with fast-sedimenting complexes.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(4):887-91.
1985: Furneaux H M; Perkins K K; Freyer G A; Arenas J; Hurwitz J
Isolation and characterization of two fractions from HeLa cells required for mRNA splicing in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(13):4351-5.
1985: Perkins K K; Furneaux H; Hurwitz J
Isolation and characterization of an RNA ligase from HeLa cells.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(3):684-8.
1983: Furneaux H; Pick L; Hurwitz J
Isolation and characterization of RNA ligase from wheat germ.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(13):3933-7.
1980: Furneaux H M; Pearson C K
Intracellular NAD+ content and ADP-ribose polymerase activity of serum-stimulated baby hamster kidney fibroblasts.
Journal of cellular physiology 1980;105(3):401-7.
1980: Shuman S; Surks M; Furneaux H; Hurwitz J
Purification and characterization of a GTP-pyrophosphate exchange activity from vaccinia virions. Association of the GTP-pyrophosphate exchange activity with vaccinia mRNA guanylyltransferase . RNA (guanine-7-)methyltransferase complex (capping enzyme).
The Journal of biological chemistry 1980;255(23):11588-98.
1980: Shuman S; Spencer E; Furneaux H; Hurwitz J
The role of ATP in in vitro vaccinia virus RNA synthesis effects of AMP-PNP and ATP gamma S.
The Journal of biological chemistry 1980;255(11):5396-403.
1980: Furneaux H M; Pearson C K
Adenosine diphosphate ribose transferase from baby-hamster kidney cells (BHK-21/C13). Characterization of the reaction and product.
The Biochemical journal 1980;187(1):91-103.
1979: Furneaux H M; Pearson C K
Intracellular oxidized nicotinamide--adenine dinucleotide content and poly(adenosine disphosphate ribose) synthetase activity in serum-stimulated fibroblasts [proceedings]
Biochemical Society transactions 1979;7(4):697-9.
1979: Porteous J W; Furneaux H M; Pearson C K; Lake C M; Morrison A
Poly(adenosine diphosphate ribose) synthetase activity in nuclei of dividing and of non-dividing but differentiating intestinal epithelial cells.
The Biochemical journal 1979;180(3):455-61.
1978: Furneaux H M; Pearson C K
The effect of oxidised nicotinamide--adenine dinucleotide on ribonucleic acid synthesis in isolated nuclei from baby-hamster kidney cells (BHK-21/C13).
Biochemical Society transactions 1978;6(4):753-5.
1977: Furneaux H M; Pearson C K
Properties of poly(adenosine diphosphate ribose) polymerase from baby-hamster kidney cells (BHK-21/C13) [proceedings]
Biochemical Society transactions 1977;5(3):743-5.

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