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Andres Aguilera

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Saccharomyces cerevisiae

Physiology

Chemicals & Drugs

Genes & Molecular Sequences

Fungal Genes

Anatomy

Fungal Chromosomes

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Co-Publications
Name
12
Prado Velasco, Félix
11
García-Rubio, María
9
Luna, Rosa
8
Cortés-Ledesma, Felipe
7
Huertas, Pablo
6
Jimeno, Sonia
6
Klein, Hannah
6
Malagón, Francisco
6
González-Barrera, Sergio
6
Chávez, Sebastián
5
Wellinger, Ralf
5
Piruat, José
5
Rondón, Ana
4
Tous, Cristina
4
Gómez-González, Belén

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Publications

TOP 3
de la Loza M C Díaz; Wellinger R E; Aguilera A
Stimulation of direct-repeat recombination by RNA polymerase III transcription.
Pardo B; Gómez-González B; Aguilera A
DNA repair in mammalian cells: DNA double-strand break repair: how to fix a broken relationship.
Huertas Pablo; Cortés-Ledesma Felipe; Sartori Alessandro A; Aguilera Andrés; Jackson Stephen P
CDK targets Sae2 to control DNA-end resection and homologous recombination.

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All Publications

2009: de la Loza M C Díaz; Wellinger R E; Aguilera A
Stimulation of direct-repeat recombination by RNA polymerase III transcription.
DNA repair 2009;8(5):620-6.
2009: Pardo B; Gómez-González B; Aguilera A
DNA repair in mammalian cells: DNA double-strand break repair: how to fix a broken relationship.
Cellular and molecular life sciences : CMLS 2009;66(6):1039-56.
2008: Huertas Pablo; Cortés-Ledesma Felipe; Sartori Alessandro A; Aguilera Andrés; Jackson Stephen P
CDK targets Sae2 to control DNA-end resection and homologous recombination.
Nature 2008;455(7213):689-92.
2008: Jimeno Sonia; García-Rubio Maria; Luna Rosa; Aguilera Andrés
A reduction in RNA polymerase II initiation rate suppresses hyper-recombination and transcription-elongation impairment of THO mutants.
Molecular genetics and genomics : MGG 2008;280(4):327-36.
2008: González-Aguilera Cristina; Tous Cristina; Gómez-González Belén; Huertas Pablo; Luna Rosa; Aguilera Andrés
The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability.
Molecular biology of the cell 2008;19(10):4310-8.
2008: Luna Rosa; Gaillard Hélène; González-Aguilera Cristina; Aguilera Andrés
Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleus.
Chromosoma 2008;117(4):319-31.
2008: Aguilera Andrés; Gómez-González Belén
Genome instability: a mechanistic view of its causes and consequences.
Nature reviews. Genetics 2008;9(3):204-17.
2008: García-Rubio María; Chávez Sebastián; Huertas Pablo; Tous Cristina; Jimeno Sonia; Luna Rosa; Aguilera Andrés
Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity.
Molecular genetics and genomics : MGG 2008;279(2):123-32.
2007: Tous Cristina; Aguilera Andrés
Impairment of transcription elongation by R-loops in vitro.
Biochemical and biophysical research communications 2007;360(2):428-32.
2007: Gómez-González Belén; Aguilera Andrés
Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(20):8409-14.
2007: Cortés-Ledesma Felipe; de Piccoli Giaccomo; Haber James E; Aragón Luis; Aguilera Andrés
SMC proteins, new players in the maintenance of genomic stability.
Cell cycle (Georgetown, Tex.) 2007;6(8):914-8.
2007: Aguilera Andrés; Boulton Simon J
How to exchange your partner. Workshop on recombination mechanisms and the maintenance of genomic stability.
EMBO reports 2007;8(1):28-33.
2007: Cortés-Ledesma Felipe; Tous Cristina; Aguilera Andrés
Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication.
Nucleic acids research 2007;35(19):6560-70.
2007: Gaillard Hélène; Wellinger Ralf Erik; Aguilera Andrés
A new connection of mRNP biogenesis and export with transcription-coupled repair.
Nucleic acids research 2007;35(12):3893-906.
2006: Huertas Pablo; García-Rubio María L; Wellinger Ralf E; Luna Rosa; Aguilera Andrés
An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination.
Molecular and cellular biology 2006;26(20):7451-65.
2006: De Piccoli Giacomo; Cortes-Ledesma Felipe; Ira Gregory; Torres-Rosell Jordi; Uhle Stefan; Farmer Sarah; Hwang Ji-Young; Machin Felix; Ceschia Audrey; McAleenan Alexandra; Cordon-Preciado Violeta; Clemente-Blanco Andrés; Vilella-Mitjana Felip; Ullal Pranav; Jarmuz Adam; Leitao Beatriz; Bressan Debra; Dotiwala Farokh; Papusha Alma; Zhao Xiaolan; Myung Kyungjae; Haber James E; Aguilera Andrés; Aragón Luis
Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination.
Nature cell biology 2006;8(9):1032-4.
2006: Cortés-Ledesma Felipe; Aguilera Andrés
Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange.
EMBO reports 2006;7(9):919-26.
2006: Friedberg Errol C; Aguilera Andres; Gellert Martin; Hanawalt Philip C; Hays John B; Lehmann Alan R; Lindahl Tomas; Lowndes Noel; Sarasin Alain; Wood Richard D
DNA repair: from molecular mechanism to human disease.
DNA repair 2006;5(8):986-96.
2006: Jimeno Sonia; Luna Rosa; García-Rubio María; Aguilera Andrés
Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants.
Molecular and cellular biology 2006;26(12):4387-98.
2006: Wellinger Ralf E; Prado Félix; Aguilera Andrés
Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex.
Molecular and cellular biology 2006;26(8):3327-34.
2005: Aguilera Andrés
mRNA processing and genomic instability.
Nature structural & molecular biology 2005;12(9):737-8.
2005: Luna Rosa; Jimeno Sonia; Marín Mercedes; Huertas Pablo; García-Rubio María; Aguilera Andrés
Interdependence between transcription and mRNP processing and export, and its impact on genetic stability.
Molecular cell 2005;18(6):711-22.
2005: Aguilera Andrés
Cotranscriptional mRNP assembly: from the DNA to the nuclear pore.
Current opinion in cell biology 2005;17(3):242-50.
2005: Prado Félix; Aguilera Andrés
Impairment of replication fork progression mediates RNA polII transcription-associated recombination.
The EMBO journal 2005;24(6):1267-76.
2005: Prado Félix; Aguilera Andrés
Partial depletion of histone H4 increases homologous recombination-mediated genetic instability.
Molecular and cellular biology 2005;25(4):1526-36.
2004: Cortés-Ledesma Felipe; Malagón Francisco; Aguilera Andrés
A novel yeast mutation, rad52-L89F, causes a specific defect in Rad51-independent recombination that correlates with a reduced ability of Rad52-L89F to interact with Rad59.
Genetics 2004;168(1):553-7.
2004: Bourbon Henri-Marc; Aguilera Andres; Ansari Aseem Z; Asturias Francisco J; Berk Arnold J; Bjorklund Stefan; Blackwell T Keith; Borggrefe Tilman; Carey Michael; Carlson Marian; Conaway Joan W; Conaway Ronald C; Emmons Scott W; Fondell Joseph D; Freedman Leonard P; Fukasawa Toshio; Gustafsson Claes M; Han Min; He Xi; Herman Paul K; Hinnebusch Alan G; Holmberg Steen; Holstege Frank C; Jaehning Judith A; Kim Young-Joon; Kuras Laurent; Leutz Achim; Lis John T; Meisterernest Michael; Naar Anders M; Nasmyth Kim; Parvin Jeffrey D; Ptashne Mark; Reinberg Danny; Ronne Hans; Sadowski Ivan; Sakurai Hiroshi; Sipiczki Matthias; Sternberg Paul W; Stillman David J; Strich Randy; Struhl Kevin; Svejstrup Jasper Q; Tuck Simon; Winston Fred; Roeder Robert G; Kornberg Roger D
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.
Molecular cell 2004;14(5):553-7.
2004: Prado Félix; Cortés-Ledesma Felipe; Aguilera Andrés
The absence of the yeast chromatin assembly factor Asf1 increases genomic instability and sister chromatid exchange.
EMBO reports 2004;5(5):497-502.
2004: Rondón Ana G; Gallardo Mercedes; García-Rubio María; Aguilera Andrés
Molecular evidence indicating that the yeast PAF complex is required for transcription elongation.
EMBO reports 2004;5(1):47-53.
2003: García-Rubio M; Huertas P; González-Barrera S; Aguilera A
Recombinogenic effects of DNA-damaging agents are synergistically increased by transcription in Saccharomyces cerevisiae. New insights into transcription-associated recombination.
Genetics 2003;165(2):457-66.
2003: Rondón Ana G; Jimeno Sonia; García-Rubio María; Aguilera Andrés
Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation.
The Journal of biological chemistry 2003;278(40):39037-43.
2003: Huertas Pablo; Aguilera Andrés
Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination.
Molecular cell 2003;12(3):711-21.
2003: Prado Félix; Aguilera Andrés
Control of cross-over by single-strand DNA resection.
Trends in genetics : TIG 2003;19(8):428-31.
2003: González-Barrera Sergio; Cortés-Ledesma Felipe; Wellinger Ralf E; Aguilera Andrés
Equal sister chromatid exchange is a major mechanism of double-strand break repair in yeast.
Molecular cell 2003;11(6):1661-71.
2003: Marín Antonio; Gallardo Mercedes; Kato Yuki; Shirahige Katsuhiko; Gutiérrez Gabriel; Ohta Kunihiro; Aguilera Andrés
Relationship between G+C content, ORF-length and mRNA concentration in Saccharomyces cerevisiae.
Yeast (Chichester, England) 2003;20(8):703-11.
2003: Gallardo Mercedes; Luna Rosa; Erdjument-Bromage Hediye; Tempst Paul; Aguilera Andres
Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism.
The Journal of biological chemistry 2003;278(26):24225-32.
2003: Rondón Ana G; García-Rubio María; González-Barrera Sergio; Aguilera Andrés
Molecular evidence for a positive role of Spt4 in transcription elongation.
The EMBO journal 2003;22(3):612-20.
2003: Prado Félix; Cortés-Ledesma Felipe; Huertas Pablo; Aguilera Andrés
Mitotic recombination in Saccharomyces cerevisiae.
Current genetics 2003;42(4):185-98.
2002: González-Barrera Sergio; García-Rubio María; Aguilera Andrés
Transcription and double-strand breaks induce similar mitotic recombination events in Saccharomyces cerevisiae.
Genetics 2002;162(2):603-14.
2002: Jimeno S; Rondón A G; Luna R; Aguilera A
The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability.
The EMBO journal 2002;21(13):3526-35.
2002: González-Barrera Sergio; Prado Félix; Verhage Richard; Brouwer Jaap; Aguilera Andrés
Defective nucleotide excision repair in yeast hpr1 and tho2 mutants.
Nucleic acids research 2002;30(10):2193-201.
2002: Strässer Katja; Masuda Seiji; Mason Paul; Pfannstiel Jens; Oppizzi Marisa; Rodriguez-Navarro Susana; Rondón Ana G; Aguilera Andres; Struhl Kevin; Reed Robin; Hurt Ed
TREX is a conserved complex coupling transcription with messenger RNA export.
Nature 2002;417(6886):304-8.
2002: Ayora Silvia; Piruat José I; Luna Rosa; Reiss Bernd; Russo Vincenzo E A; Aguilera Andrés; Alonso Juan C
Characterization of two highly similar Rad51 homologs of Physcomitrella patens.
Journal of molecular biology 2002;316(1):35-49.
2002: Aguilera Andrés
The connection between transcription and genomic instability.
The EMBO journal 2002;21(3):195-201.
2001: Chávez S; García-Rubio M; Prado F; Aguilera A
Hpr1 is preferentially required for transcription of either long or G+C-rich DNA sequences in Saccharomyces cerevisiae.
Molecular and cellular biology 2001;21(20):7054-64.
2001: Malagón F; Aguilera A
Yeast spt6-140 mutation, affecting chromatin and transcription, preferentially increases recombination in which Rad51p-mediated strand exchange is dispensable.
Genetics 2001;158(2):597-611.
2001: Aguilera A
Double-strand break repair: are Rad51/RecA--DNA joints barriers to DNA replication?
Trends in genetics : TIG 2001;17(6):318-21.
2001: Gallardo M; Aguilera A
A new hyperrecombination mutation identifies a novel yeast gene, THP1, connecting transcription elongation with mitotic recombination.
Genetics 2001;157(1):79-89.
2000: Chávez S; Beilharz T; Rondón A G; Erdjument-Bromage H; Tempst P; Svejstrup J Q; Lithgow T; Aguilera A
A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae.
The EMBO journal 2000;19(21):5824-34.
2000: Aguilera A; Chávez S; Malagón F
Mitotic recombination in yeast: elements controlling its incidence.
Yeast (Chichester, England) 2000;16(8):731-54.
2000: Prado F; González-Barrera S; Aguilera A
RAD52-dependent and -independent homologous recombination initiated by Flp recombinase at a single FRT site flanked by direct repeats.
Molecular & general genetics : MGG 2000;263(1):73-80.
1999: Malagón F; Aguilera A
Construction and genetic analysis of S. cerevisiae deletants of six novel ORFs from chromosome II.
Yeast (Chichester, England) 1999;15(10B):955-61.
1998: Malagón F; Aguilera A
Genetic stability and DNA rearrangements associated with a 2 x 1.1-Kb perfect palindrome in Escherichia coli.
Molecular & general genetics : MGG 1998;259(6):639-44.
1998: Piruat J I; Aguilera A
A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination.
The EMBO journal 1998;17(16):4859-72.
1997: Piruat J I; Chávez S; Aguilera A
The yeast HRS1 gene is involved in positive and negative regulation of transcription and shows genetic characteristics similar to SIN4 and GAL11.
Genetics 1997;147(4):1585-94.
1997: Chávez S; Aguilera A
The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability.
Genes & development 1997;11(24):3459-70.
1997: Prado F; Piruat J I; Aguilera A
Recombination between DNA repeats in yeast hpr1delta cells is linked to transcription elongation.
The EMBO journal 1997;16(10):2826-35.
1996: Piruat J I; Aguilera A
Mutations in the yeast SRB2 general transcription factor suppress hpr1-induced recombination and show defects in DNA repair.
Genetics 1996;143(4):1533-42.
1996: Malagón F; Aguilera A
Differential intrachromosomal hyper-recombination phenotype of spt4 and spt6 mutants of S. cerevisiae.
Current genetics 1996;30(2):101-6.
1996: Santos-Rosa H; Clever B; Heyer W D; Aguilera A
The yeast HRS1 gene encodes a polyglutamine-rich nuclear protein required for spontaneous and hpr1-induced deletions between direct repeats.
Genetics 1996;142(3):705-16.
1995: Aguilera A
Genetic evidence for different RAD52-dependent intrachromosomal recombination pathways in Saccharomyces cerevisiae.
Current genetics 1995;27(4):298-305.
1995: Santos-Rosa H; Aguilera A
Isolation and genetic analysis of extragenic suppressors of the hyper-deletion phenotype of the Saccharomyces cerevisiae hpr1 delta mutation.
Genetics 1995;139(1):57-66.
1995: Prado F; Aguilera A
Role of reciprocal exchange, one-ended invasion crossover and single-strand annealing on inverted and direct repeat recombination in yeast: different requirements for the RAD1, RAD10, and RAD52 genes.
Genetics 1995;139(1):109-23.
1994: Santos-Rosa H; Aguilera A
Increase in incidence of chromosome instability and non-conservative recombination between repeats in Saccharomyces cerevisiae hpr1 delta strains.
Molecular & general genetics : MGG 1994;245(2):224-36.
1994: Prado F; Aguilera A
New in-vivo cloning methods by homologous recombination in yeast.
Current genetics 1994;25(2):180-3.
1994: Aguilera A
Formamide sensitivity: a novel conditional phenotype in yeast.
Genetics 1994;136(1):87-91.
1991: Rong L; Palladino F; Aguilera A; Klein H L
The hyper-gene conversion hpr5-1 mutation of Saccharomyces cerevisiae is an allele of the SRS2/RADH gene.
Genetics 1991;127(1):75-85.
1990: Mayer V W; Aguilera A
High levels of chromosome instability in polyploids of Saccharomyces cerevisiae.
Mutation research 1990;231(2):177-86.
1990: Aguilera A; Klein H L
HPR1, a novel yeast gene that prevents intrachromosomal excision recombination, shows carboxy-terminal homology to the Saccharomyces cerevisiae TOP1 gene.
Molecular and cellular biology 1990;10(4):1439-51.
1990: Aguilera A; Moskowitz P; Klein H L
Molecular analysis of RGP1, a new yeast gene required for proper mitotic growth.
Nucleic acids research 1990;18(4):1064.
1989: Aguilera A; Klein H L
Yeast intrachromosomal recombination: long gene conversion tracts are preferentially associated with reciprocal exchange and require the RAD1 and RAD3 gene products.
Genetics 1989;123(4):683-94.
1989: Aguilera A; Klein H L
Genetic and molecular analysis of recombination events in Saccharomyces cerevisiae occurring in the presence of the hyper-recombination mutation hpr1.
Genetics 1989;122(3):503-17.
1989: Heinisch J; Ritzel R G; von Borstel R C; Aguilera A; Rodicio R; Zimmermann F K
The phosphofructokinase genes of yeast evolved from two duplication events.
Gene 1989;78(2):309-21.
1988: Aguilera A; Klein H L
Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations.
Genetics 1988;119(4):779-90.
1988: Aguilera A
Mitotic gene conversion of large DNA heterologies in Saccharomyces cerevisiae.
Molecular & general genetics : MGG 1988;211(3):455-8.
1987: Aguilera A
Mutations suppressing the effects of a deletion of the phosphoglucose isomerase gene PGI1 in Saccharomyces cerevisiae.
Current genetics 1987;11(6-7):429-34.
1986: Aguilera A
Deletion of the phosphoglucose isomerase structural gene makes growth and sporulation glucose dependent in Saccharomyces cerevisiae.
Molecular & general genetics : MGG 1986;204(2):310-6.
1986: Aguilera A; Benítez T
Ethanol-sensitive mutants of Saccharomyces cerevisiae.
Archives of microbiology 1986;143(4):337-44.
1986: Aguilera A; Zimmermann F K
Isolation and molecular analysis of the phosphoglucose isomerase structural gene of Saccharomyces cerevisiae.
Molecular & general genetics : MGG 1986;202(1):83-9.
1985: Aguilera A; Benítez T
Role of mitochondria in ethanol tolerance of Saccharomyces cerevisiae.
Archives of microbiology 1985;142(4):389-92.

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