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Lorenz Meinel

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Chemicals & Drugs

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Microspheres

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Publications

TOP 3
Lorenz Meinel; David L Kaplan
Silk constructs for delivery of musculoskeletal therapeutics.
Tessa Luhmann; Oliver Germershaus; Jürgen Groll; Lorenz Meinel
Bone targeting for the treatment of osteoporosis.
Anne J Meinel; Oliver Germershaus; Tessa Luhmann; Hans P Merkle; Lorenz Meinel
Electrospun matrices for localized drug delivery: current technologies and selected biomedical applications.

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All Publications

2012: Lorenz Meinel; David L Kaplan
Silk constructs for delivery of musculoskeletal therapeutics.
Advanced drug delivery reviews 2012;64(12):1111-22.
2012: Tessa Luhmann; Oliver Germershaus; Jürgen Groll; Lorenz Meinel
Bone targeting for the treatment of osteoporosis.
Journal of controlled release : official journal of the Controlled Release Society 2012;161(2):198-213.
2012: Anne J Meinel; Oliver Germershaus; Tessa Luhmann; Hans P Merkle; Lorenz Meinel
Electrospun matrices for localized drug delivery: current technologies and selected biomedical applications.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012;81(1):1-13.
2012: Franz Jakob; Lorenz Meinel; Ulrich Nöth; Maximilian Rudert; Matthias Schieker; Heike Walles; Denitsa Docheva; Regina Ebert; Jürgen Groll
In situ guided tissue regeneration in musculoskeletal diseases and aging : Implementing pathology into tailored tissue engineering strategies.
Cell and tissue research 2012;347(3):725-35.
2012: Pascale Holzerny; Baskim Ajdini; Katharina Bruno; Wolf Heusermann; Lorenz Meinel; Michael Schuleit; Michael Keller
Biophysical properties of chitosan/siRNA polyplexes: profiling the polymer/siRNA interactions and bioactivity.
Journal of controlled release : official journal of the Controlled Release Society 2012;157(2):297-304.
2011: Esther Wenk; Hans P Merkle; Lorenz Meinel
Silk fibroin as a vehicle for drug delivery applications.
Journal of controlled release : official journal of the Controlled Release Society 2011;150(2):128-41.
2010: Esther Wenk; Amanda R Murphy; David L Kaplan; Lorenz Meinel; Hans P Merkle; Lorenz uebersax
The use of sulfonated silk fibroin derivatives to control binding, delivery and potency of FGF-2 in tissue regeneration.
Biomaterials 2010;31(6):1403-13.
2010: Henri Hagenmüller; Marco Hitz; Hans P Merkle; Lorenz Meinel; Ralph Müller
Design and validation of a novel bioreactor principle to combine online micro-computed tomography monitoring and mechanical loading in bone tissue engineering.
The Review of scientific instruments 2010;81(1):014303.
2009: Marcos Garcia-Fuentes; Anne J Meinel; Monika Hilbe; Lorenz Meinel; Hans P Merkle
Silk fibroin/hyaluronan scaffolds for human mesenchymal stem cell culture in tissue engineering.
Biomaterials 2009;30(28):5068-76.
2009: Lorenz uebersax; Hans P Merkle; Lorenz Meinel
Biopolymer-based growth factor delivery for tissue repair: from natural concepts to engineered systems.
Tissue engineering. Part B, Reviews 2009;15(3):263-89.
2009: Anne J Meinel; Kristopher E Kubow; Enrico Klotzsch; Marcos Garcia-Fuentes; Michael L Smith; Viola Vogel; Hans P Merkle; Lorenz Meinel
Optimization strategies for electrospun silk fibroin tissue engineering scaffolds.
Biomaterials 2009;30(17):3058-67.
2009: Esther Wenk; Anne J Meinel; Sarah Wildy; Hans P Merkle; Lorenz Meinel
Microporous silk fibroin scaffolds embedding PLGA microparticles for controlled growth factor delivery in tissue engineering.
Biomaterials 2009;30(13):2571-81.
2009: Xiaoqin Wang; Esther Wenk; Xiaohui Zhang; Lorenz Meinel; Gordana Vunjak-Novakovic; David L Kaplan
Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering.
Journal of controlled release : official journal of the Controlled Release Society 2009;134(2):81-90.
2008: Esther Wenk; Anne J Wandrey; Hans P Merkle; Lorenz Meinel
Silk fibroin spheres as a platform for controlled drug delivery.
Journal of controlled release : official journal of the Controlled Release Society 2008;132(1):26-34.
2008: Alexander Augst; Darja Marolt; Lisa E Freed; Charu Vepari; Lorenz Meinel; Michelle Farley; Robert Fajardo; Nipun Patel; Martha Gray; David L Kaplan; Gordana Vunjak-Novakovic
Effects of chondrogenic and osteogenic regulatory factors on composite constructs grown using human mesenchymal stem cells, silk scaffolds and bioreactors.
Journal of the Royal Society, Interface / the Royal Society 2008;5(25):929-39.
2008: Lorenz uebersax; Hans P Merkle; Lorenz Meinel
Insulin-like growth factor I releasing silk fibroin scaffolds induce chondrogenic differentiation of human mesenchymal stem cells.
Journal of controlled release : official journal of the Controlled Release Society 2008;127(1):12-21.
2008: Marcos Garcia-Fuentes; elisabeth giger; Lorenz Meinel; Hans P Merkle
The effect of hyaluronic acid on silk fibroin conformation.
Biomaterials 2008;29(6):633-42.
2007: Lorenz uebersax; Marta Mattotti; Michaël Y Papaloïzos; Hans P Merkle; Bruno Gander; Lorenz Meinel
Silk fibroin matrices for the controlled release of nerve growth factor (NGF).
Biomaterials 2007;28(30):4449-60.
2007: Xiaoqin Wang; Esther Wenk; Xiao Hu; Guillermo R Castro; Lorenz Meinel; Xianyan Wang; Chunmei Li; Hans Merkle; David L Kaplan
Silk coatings on PLGA and alginate microspheres for protein delivery.
Biomaterials 2007;28(28):4161-9.
2007: Henri Hagenmüller; Sandra Hofmann; Thomas Kohler; Hans P Merkle; David L Kaplan; Gordana Vunjak-Novakovic; Ralph Müller; Lorenz Meinel
Non-invasive time-lapsed monitoring and quantification of engineered bone-like tissue.
Annals of biomedical engineering 2007;35(10):1657-67.
2007: Carl A Kirker-Head; Vassilis Karageorgiou; Sandra Hofmann; Robert Fajardo; Oliver Betz; Hans P Merkle; Monika Hilbe; Brigitte von Rechenberg; John McCool; L Abrahamsen; A Nazarian; E Cory; M Curtis; David Kaplan; Lorenz Meinel
BMP-silk composite matrices heal critically sized femoral defects.
Bone 2007;41(2):247-55.
2007: Harry van Lenthe; Henri Hagenmüller; Marc Bohner; Scott J Hollister; Lorenz Meinel; Ralph Müller
Nondestructive micro-computed tomography for biological imaging and quantification of scaffold-bone interaction in vivo.
Biomaterials 2007;28(15):2479-90.
2007: Xiaoqin Wang; Esther Wenk; Akira Matsumoto; Lorenz Meinel; Chumei Li; David L Kaplan
Silk microspheres for encapsulation and controlled release.
Journal of controlled release : official journal of the Controlled Release Society 2007;117(3):360-70.
2007: Sandra Hofmann; Henri Hagenmüller; Annette M Koch; Ralph Müller; Gordana Vunjak-Novakovic; David L Kaplan; Hans P Merkle; Lorenz Meinel
Control of in vitro tissue-engineered bone-like structures using human mesenchymal stem cells and porous silk scaffolds.
Biomaterials 2007;28(6):1152-62.
2006: Lorenz uebersax; Henri Hagenmüller; Sandra Hofmann; Emanuel Gruenblatt; Ralph Müller; Gordana Vunjak-Novakovic; David L Kaplan; Hans P Merkle; Lorenz Meinel
Effect of scaffold design on bone morphology in vitro.
Tissue engineering 2006;12(12):3417-29.
2006: Sandra Hofmann; Sven Knecht; Robert Langer; David L Kaplan; Gordana Vunjak-Novakovic; Hans P Merkle; Lorenz Meinel
Cartilage-like tissue engineering using silk scaffolds and mesenchymal stem cells.
Tissue engineering 2006;12(10):2729-38.
2006: Lorenz Meinel; Sandra Hofmann; Oliver Betz; Robert Fajardo; Hans P Merkle; Robert Langer; Christopher H Evans; Gordana Vunjak-Novakovic; David L Kaplan
Osteogenesis by human mesenchymal stem cells cultured on silk biomaterials: comparison of adenovirus mediated gene transfer and protein delivery of BMP-2.
Biomaterials 2006;27(28):4993-5002.
2006: Lorenz Meinel; Oliver Betz; Robert Fajardo; Sandra Hofmann; A Nazarian; E Cory; Monika Hilbe; John McCool; Robert Langer; Gordana Vunjak-Novakovic; Hans P Merkle; B Rechenberg; David L Kaplan; Carl A Kirker-Head
Silk based biomaterials to heal critical sized femur defects.
Bone 2006;39(4):922-31.
2006: Lorenz uebersax; Denise E Fedele; Claudia Schumacher; David L Kaplan; Hans P Merkle; Detlev Boison; Lorenz Meinel
The support of adenosine release from adenosine kinase deficient ES cells by silk substrates.
Biomaterials 2006;27(26):4599-607.
2006: Vassilis Karageorgiou; Michael Tomkins; Robert Fajardo; Lorenz Meinel; Brian Snyder; Katherine Wade; Jake Chen; Gordana Vunjak-Novakovic; David L Kaplan
Porous silk fibroin 3-D scaffolds for delivery of bone morphogenetic protein-2 in vitro and in vivo.
Journal of biomedical materials research. Part A 2006;78(2):324-34.
2006: Sandra Hofmann; C T Wong Po Foo; Fernanda F Rossetti; Marcus Textor; Gordana Vunjak-Novakovic; David L Kaplan; Hans P Merkle; Lorenz Meinel
Silk fibroin as an organic polymer for controlled drug delivery.
Journal of controlled release : official journal of the Controlled Release Society 2006;111(1-2):219-27.
2005: Lorenz Meinel; Robert Fajardo; Sandra Hofmann; Robert Langer; Jake Chen; Brian Snyder; Gordana Vunjak-Novakovic; David Kaplan
Silk implants for the healing of critical size bone defects.
Bone 2005;37(5):688-98.
2005: Gordana Vunjak-Novakovic; Lorenz Meinel; Gregory H Altman; David Kaplan
Bioreactor cultivation of osteochondral grafts.
Orthodontics & craniofacial research 2005;8(3):209-18.
2005: Vera Luginbuehl; Esther Wenk; Annette Koch; Bruno Gander; Hans P Merkle; Lorenz Meinel
Insulin-like growth factor I-releasing alginate-tricalciumphosphate composites for bone regeneration.
Pharmaceutical research 2005;22(6):940-50.
2005: Lorenz Meinel; Sandra Hofmann; Vassilis Karageorgiou; Carl A Kirker-Head; John McCool; Gloria A Gronowicz; Ludwig Zichner; Robert Langer; Gordana Vunjak-Novakovic; David L Kaplan
The inflammatory responses to silk films in vitro and in vivo.
Biomaterials 2005;26(2):147-55.
2004: Vassilis Karageorgiou; Lorenz Meinel; Sandra Hofmann; Ajay Malhotra; Vladimir Volloch; David Kaplan
Bone morphogenetic protein-2 decorated silk fibroin films induce osteogenic differentiation of human bone marrow stromal cells.
Journal of biomedical materials research. Part A 2004;71(3):528-37.
2004: Lorenz Meinel; Sandra Hofmann; Vassilis Karageorgiou; Ludwig Zichner; Robert Langer; David Kaplan; Gordana Vunjak-Novakovic
Engineering cartilage-like tissue using human mesenchymal stem cells and silk protein scaffolds.
Biotechnology and bioengineering 2004;88(3):379-91.
2004: Lorenz Meinel; Vassilis Karageorgiou; Sandra Hofmann; Robert Fajardo; Brian Snyder; Chunmei Li; Ludwig Zichner; Robert Langer; Gordana Vunjak-Novakovic; David L Kaplan
Engineering bone-like tissue in vitro using human bone marrow stem cells and silk scaffolds.
Journal of biomedical materials research. Part A 2004;71(1):25-34.
2004: Vera Luginbuehl; Lorenz Meinel; Hans P Merkle; Bruno Gander
Localized delivery of growth factors for bone repair.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;58(2):197-208.
2004: Alexander O El-Warrak; Marvin Olmstead; Rebecca Schneider; Lorenz Meinel; Regula Bettschart-Wolfisberger; Margarete K Akens; Joerg Auer; Brigitte von Rechenberg
An experimental animal model of aseptic loosening of hip prostheses in sheep to study early biochemical changes at the interface membrane.
BMC musculoskeletal disorders 2004;5():7.
2004: Lorenz Meinel; Vassilis Karageorgiou; Robert Fajardo; Brian Snyder; Vivek Shinde-Patil; Ludwig Zichner; David Kaplan; Robert Langer; Gordana Vunjak-Novakovic
Bone tissue engineering using human mesenchymal stem cells: effects of scaffold material and medium flow.
Annals of biomedical engineering 2004;32(1):112-22.
2003: Lorenz Meinel; Evangelos Zoidis; Jürgen Zapf; Paul O Hassa; Michael Hottiger; Joerg A Auer; Rebecca Schneider; Bruno Gander; Vera Luginbuehl; Regula Bettschart-Wolfisberger; Oscar E Illi; Hans P Merkle; Brigitte von Rechenberg
Localized insulin-like growth factor I delivery to enhance new bone formation.
Bone 2003;33(4):660-72.
2002: H Jager; Lorenz Meinel; Birgit M Dietz; C Lapke; Rudolf Bauer; H P Merkle; J Heilmann
Transport of alkamides from Echinacea species through Caco-2 monolayers.
Planta medica 2002;68(5):469-71.
2002: Evangelos Zoidis; Martina Gosteli-Peter; Claudia Ghirlanda-Keller; Lorenz Meinel; Jürgen Zapf; Christoph Schmid
IGF-I and GH stimulate Phex mRNA expression in lungs and bones and 1,25-dihydroxyvitamin D(3) production in hypophysectomized rats.
European journal of endocrinology / European Federation of Endocrine Societies 2002;146(1):97-105.
2001: Marc Brede; Kerstin Hadamek; Lorenz Meinel; Frank Wiesmann; J Peters; Stefan Engelhardt; Andreas Simm; Axel Haase; Martin J Lohse; Lutz Hein
Vascular hypertrophy and increased P70S6 kinase in mice lacking the angiotensin II AT(2) receptor.
Circulation 2001;104(21):2602-7.
2001: AJ Chruscinski; Marc Brede; Lorenz Meinel; Martin J Lohse; Brian K Kobilka; Lutz Hein
Differential distribution of beta-adrenergic receptor subtypes in blood vessels of knockout mice lacking beta(1)- or beta(2)-adrenergic receptors.
Molecular pharmacology 2001;60(5):955-62.
2001: Lorenz Meinel; O E Illi; Jürgen Zapf; M Malfanti; H Peter Merkle; Bruno Gander
Stabilizing insulin-like growth factor-I in poly(D,L-lactide-co-glycolide) microspheres.
Journal of controlled release : official journal of the Controlled Release Society 2001;70(1-2):193-202.
1997: Lutz Hein; Lorenz Meinel; RE Pratt; Victor J Dzau; Brian K Kobilka
Intracellular trafficking of angiotensin II and its AT1 and AT2 receptors: evidence for selective sorting of receptor and ligand.
Molecular endocrinology (Baltimore, Md.) 1997;11(9):1266-77.