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Edison Liu

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Oligonucleotide Array Sequence Analysis

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Koichiro Inaki; Axel M Hillmer; Leena Ukil; Fei Yao; Xing Yi Woo; Leah A Vardy; Kelson Folkvard Braaten Zawack; Charlie Wah Heng Lee; Pramila Ariyaratne; Yang Sun Chan; Kartiki Vasant Desai; Jonas Bergh; Per Hall; Thomas Choudary Putti; Wai Loon Ong; Atif Shahab; Valere Cacheux-Rataboul; Radha Krishna Murthy Karuturi; Wing-Kin Sung; Xiaoan Ruan; Guillaume Bourque; Yijun Ruan; Edison Liu
Transcriptional consequences of genomic structural aberrations in breast cancer.
Roy Joseph; Yuriy L Orlov; Mikael Huss; Wenjie Sun; Say Li Kong; Leena Ukil; You Fu Pan; Guoliang Li; Michael Lim; Jane S Thomsen; Yijun Ruan; Neil D Clarke; Shyam Prabhakar; Edwin Cheung; Edison Liu
Integrative model of genomic factors for determining binding site selection by estrogen receptor-α.
J Kang; P X Qian; VIJAY PANDEY; J K Perry; L D Miller; Edison Liu; T Zhu; D X Liu; Peter E Lobie
Artemin is estrogen regulated and mediates antiestrogen resistance in mammary carcinoma.

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All Publications

2011: Koichiro Inaki; Axel M Hillmer; Leena Ukil; Fei Yao; Xing Yi Woo; Leah A Vardy; Kelson Folkvard Braaten Zawack; Charlie Wah Heng Lee; Pramila Ariyaratne; Yang Sun Chan; Kartiki Vasant Desai; Jonas Bergh; Per Hall; Thomas Choudary Putti; Wai Loon Ong; Atif Shahab; Valere Cacheux-Rataboul; Radha Krishna Murthy Karuturi; Wing-Kin Sung; Xiaoan Ruan; Guillaume Bourque; Yijun Ruan; Edison Liu
Transcriptional consequences of genomic structural aberrations in breast cancer.
Genome research 2011;21(5):676-87.
2010: Roy Joseph; Yuriy L Orlov; Mikael Huss; Wenjie Sun; Say Li Kong; Leena Ukil; You Fu Pan; Guoliang Li; Michael Lim; Jane S Thomsen; Yijun Ruan; Neil D Clarke; Shyam Prabhakar; Edwin Cheung; Edison Liu
Integrative model of genomic factors for determining binding site selection by estrogen receptor-α.
Molecular systems biology 2010;6():456.
2010: J Kang; P X Qian; VIJAY PANDEY; J K Perry; L D Miller; Edison Liu; T Zhu; D X Liu; Peter E Lobie
Artemin is estrogen regulated and mediates antiestrogen resistance in mammary carcinoma.
Oncogene 2010;29(22):3228-40.
2009: Kristjana Einarsdóttir; H Darabi; Kamila Czene; Yuqing Li; Y L Low; Y Q Li; C Bonnard; Sara Wedrén; Edison Liu; Per Hall; Jianjun Liu; Keith Humphreys
Common genetic variability in ESR1 and EGF in relation to endometrial cancer risk and survival.
British journal of cancer 2009;100(8):1358-64.
2009: Melissa J Fullwood; Chia-Lin Wei; Edison Liu; Yijun Ruan
Next-generation DNA sequencing of paired-end tags (PET) for transcriptome and genome analyses.
Genome research 2009;19(4):521-32.
2009: Mohamed Sabry Hamza; Sebastian Pott; Vinsensius B Vega; Jane S Thomsen; Gopalan Srinivasan Kandhadayar; Patrick Wei Pern Ng; Kuo Ping Chiu; Sven Pettersson; Chia Lin Wei; Yijun Ruan; Edison Liu
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis.
PloS one 2009;4(3):e4907.
2008: Guillaume Bourque; Bernard Leong; Vinsensius B Vega; Xi Chen; Yen Ling Lee; Kandhadayar G Srinivasan; Joon-Lin Chew; Yijun Ruan; Chia-Lin Wei; Huck-Hui Ng; Edison Liu
Evolution of the mammalian transcription factor binding repertoire via transposable elements.
Genome research 2008;18(11):1752-62.
2008: Arthur Kwok Leung Cheung; Hong Lok Lung; Siu Chun Hung; Evan Wai Lok Law; Yue Cheng; Wing Lung Yau; Dhinoth Kumar Bangarusamy; Lance D Miller; Edison Liu; Jian-Yong Shao; Chang-Wei Kou; Daniel Chua; Eugene R Zabarovsky; Sai Wah Tsao; Eric J Stanbridge; Maria Li Lung
Functional analysis of a cell cycle-associated, tumor-suppressive gene, protein tyrosine phosphatase receptor type G, in nasopharyngeal carcinoma.
Cancer research 2008;68(19):8137-45.
2008: Andreas Neubauer; Kati Maharry; Krzysztof Mrózek; Christian Thiede; Guido Marcucci; Peter Paschka; Robert J Mayer; Richard A Larson; Edison Liu; Clara D Bloomfield
Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(28):4603-9.
2008: Siew Hong Lam; Sinnakarupan Mathavan; Yan Tong; Haixia Li; R Krishna Murthy Karuturi; Yilian Wu; Vinsensius B Vega; Edison Liu; Zhiyuan Gong
Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology.
PLoS genetics 2008;4(7):e1000121.
2008: Edison Liu
Functional genomics of cancer.
Current opinion in genetics & development 2008;18(3):251-6.
2008: Xia Jiang; Jing Tan; Jingsong Li; Saul Kivimäe; Xiaojing Yang; Li Zhuang; Puay Leng Lee; Mark T W Chan; Lawrence W Stanton; Edison Liu; Benjamin N R Cheyette; Qiang Yu
DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.
Cancer cell 2008;13(6):529-41.
2008: Michael P DiGiovanna; David F Stern; Susan M Edgerton; Gloria Broadwater; Lynn Dressler; Daniel R Budman; I Craig Henderson; Larry Norton; Edison Liu; Hyman Muss; Donald A Berry; Daniel F Hayes; Ann D Thor
Influence of activation state of ErbB-2 (HER-2) on response to adjuvant cyclophosphamide, doxorubicin, and fluorouracil for stage II, node-positive breast cancer: study 8541 from the Cancer and Leukemia Group B.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(14):2364-72.
2008: Daniel Barnett; Shubin Sheng; Tze Howe Charn; Abdul Waheed; William S Sly; Chin-Yo Lin; Edison Liu; Benita S Katzenellenbogen
Estrogen receptor regulation of carbonic anhydrase XII through a distal enhancer in breast cancer.
Cancer research 2008;68(9):3505-15.
2008: Josephine M Y Ko; Pui Ling Chan; Wing Lung Yau; Ho Kin Chan; King Chi Chan; Zhuo You Yu; Fung Mei Kwong; Lance D Miller; Edison Liu; Li Chun Yang; Paulisally H Y Lo; Eric J Stanbridge; Johnny C O Tang; Gopesh Srivastava; Sai Wah Tsao; Simon Law; Maria Li Lung
Monochromosome transfer and microarray analysis identify a critical tumor-suppressive region mapping to chromosome 13q14 and THSD1 in esophageal carcinoma.
Molecular cancer research : MCR 2008;6(4):592-603.
2008: Stefanie Denger; Tomi Bähr-Ivacevic; Heike Brand; George Reid; Jonathon Blake; Martin Seifert; Chin-Yo Lin; Klaus May; Vladimir Benes; Edison Liu; Frank Gannon
Transcriptome profiling of estrogen-regulated genes in human primary osteoblasts reveals an osteoblast-specific regulation of the insulin-like growth factor binding protein 4 gene.
Molecular endocrinology (Baltimore, Md.) 2008;22(2):361-79.
2008: Alfred Chi Chung Leung; Victor Chun Lam Wong; Li Chun Yang; Pui Ling Chan; Yataro Daigo; Yusuke Nakamura; Robert Z Qi; Lance David Miller; Edison Liu; Li Dong Wang; Ji-Lin Li; Simon Law; Sai Wah Tsao; Maria Li Lung
Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage-independent growth properties and impact on global gene expression in esophageal carcinoma.
International journal of cancer. Journal international du cancer 2008;122(3):587-94.
2008: Kristjana Einarsdóttir; Hatef Darabi; Yi Li; Yen Ling Low; Yu Qing Li; Carine Bonnard; Arvid Sjölander; Kamila Czene; Sara Wedrén; Edison Liu; Per Hall; Keith Humphreys; Jianjun Liu
ESR1 and EGF genetic variation in relation to breast cancer risk and survival.
Breast cancer research : BCR 2008;10(1):R15.
2007: Edison Liu
Stromal effects in breast cancer.
The New England journal of medicine 2007;357(25):2537-8.
2007: Enrico Petretto; Edison Liu; Timothy J Aitman
A gene harvest revealing the archeology and complexity of human disease.
Nature genetics 2007;39(11):1299-301.
2007: Kumarasamypet M Mohankumar; X Q Xu; T Zhu; N Kannan; L D Miller; Edison Liu; Peter D Gluckman; Saraswati Sukumar; B Starling Emerald; Peter E Lobie
HOXA1-stimulated oncogenicity is mediated by selective upregulation of components of the p44/42 MAP kinase pathway in human mammary carcinoma cells.
Oncogene 2007;26(27):3998-4008.
2007: Chin-Yo Lin; Vinsensius B Vega; Jane S Thomsen; Tao Zhang; Say Li Kong; Min Xie; Kuo Ping Chiu; Leonard Lipovich; Daniel Barnett; Fabio Stossi; Ai Li Yeo; joshy george; Vladimir Kuznetsov; Yew Kok Lee; Tze Howe Charn; Nallasivam Palanisamy; Lance D Miller; Edwin Cheung; Benita S Katzenellenbogen; Yijun Ruan; Guillaume Bourque; Chia-Lin Wei; Edison Liu
Whole-genome cartography of estrogen receptor alpha binding sites.
PLoS genetics 2007;3(6):e87.
2007: Jing Tan; Xiaojing Yang; Li Zhuang; Xia Jiang; Wei Chen; Puay Leng Lee; R K Murthy Karuturi; Patrick Boon Ooi Tan; Edison Liu; Qiang Yu
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.
Genes & development 2007;21(9):1050-63.
2007: Kristjana Einarsdóttir; Keith Humphreys; Carine Bonnard; Yuqing Li; Yi Li; Kee-Seng Chia; Edison Liu; Per Hall; Jianjun Liu; Sara Wedrén
Effect of ATM, CHEK2 and ERBB2 TAGSNPs and haplotypes on endometrial cancer risk.
Human molecular genetics 2007;16(2):154-64.
2007: Majid Eshaghi; R Krishna Murthy Karuturi; Juntao Li; Zhaoqing Chu; Edison Liu; Jianhua Liu
Global profiling of DNA replication timing and efficiency reveals that efficient replication/firing occurs late during S-phase in S. pombe.
PloS one 2007;2(8):e722.
2007: Kuo Ping Chiu; Pramila Ariyaratne; Han Xu; Adrian Tan; Patrick Ng; Edison Liu; Yijun Ruan; Chia-Lin Wei; Wing-Kin Sung
Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes.
BMC cancer 2007;7():109.
2007: Chin-Yo Lin; Anders Ström; Say Li Kong; Silke Kietz; Jane S Thomsen; Jason B S Tee; Vinsensius B Vega; Lance D Miller; Johanna Smeds; Jonas Bergh; Jan-�ke GUSTAFSSON; Edison Liu
Inhibitory effects of estrogen receptor beta on specific hormone-responsive gene expression and association with disease outcome in primary breast cancer.
Breast cancer research : BCR 2007;9(2):R25.
2007: Lance D Miller; Edison Liu
Expression genomics in breast cancer research: microarrays at the crossroads of biology and medicine.
Breast cancer research : BCR 2007;9(2):206.
2007: Edison Liu; Thomas Lemberger
Higher order structure in the cancer transcriptome and systems medicine.
Molecular systems biology 2007;3():94.
2007: Maria Nilsson; Thomas M Stulnig; Chin-Yo Lin; Ai Li Yeo; Peter Nowotny; Edison Liu; Knut R Steffensen
Liver X receptors regulate adrenal steroidogenesis and hypothalamic-pituitary-adrenal feedback.
Molecular endocrinology (Baltimore, Md.) 2007;21(1):126-37.
2006: Siew Hong Lam; Cecilia Lanny Winata; Yan Tong; Svitlana Korzh; Wen San Lim; Vladimir Korzh; Jan Spitsbergen; Sinnakarupan Mathavan; Lance D Miller; Edison Liu; Zhiyuan Gong
Transcriptome kinetics of arsenic-induced adaptive response in zebrafish liver.
Physiological genomics 2006;27(3):351-61.
2006: Tero A H Järvinen; Edison Liu
Simultaneous amplification of HER-2 (ERBB2) and topoisomerase IIalpha (TOP2A) genes--molecular basis for combination chemotherapy in cancer.
Current cancer drug targets 2006;6(7):579-602.
2006: Anna V Ivshina; joshy george; Oleg Senko; Benjamin Mow; Thomas C Putti; Johanna Smeds; Thomas Lindahl; Yudi Pawitan; Per Hall; Hans Nordgren; John E L Wong; Edison Liu; Jonas Bergh; Vladimir Kuznetsov; Lance D Miller
Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer.
Cancer research 2006;66(21):10292-301.
2006: Jennifer Eng-Wong; James C Reynolds; David Venzon; David J Liewehr; S Gantz; David N Danforth; Edison Liu; Catherine Chow; Jo Anne Zujewski
Effect of raloxifene on bone mineral density in premenopausal women at increased risk of breast cancer.
The Journal of clinical endocrinology and metabolism 2006;91(10):3941-6.
2006: Jonna Frasor; Edmund C Chang; Barry S Komm; Chin-Yo Lin; Vinsensius B Vega; Edison Liu; Lance D Miller; Johanna Smeds; Jonas Bergh; Benita S Katzenellenbogen
Gene expression preferentially regulated by tamoxifen in breast cancer cells and correlations with clinical outcome.
Cancer research 2006;66(14):7334-40.
2006: Philippe Broët; Vladimir Kuznetsov; Jonas Bergh; Edison Liu; Lance D Miller
Identifying gene expression changes in breast cancer that distinguish early and late relapse among uncured patients.
Bioinformatics (Oxford, England) 2006;22(12):1477-85.
2006: Kristjana Einarsdóttir; Keith Humphreys; Carine Bonnard; Juni Palmgren; Mark M Iles; Arvid Sjölander; Yuqing Li; Kee-Seng Chia; Edison Liu; Per Hall; Jianjun Liu; Sara Wedrén
Linkage disequilibrium mapping of CHEK2: common variation and breast cancer risk.
PLoS medicine 2006;3(6):e168.
2006: piero carninci; Albin Sandelin; Boris Lenhard; Shintaro Katayama; Kazuro Shimokawa; Jasmina Ponjavic; Colin Semple; Martin Taylor; Pär G Engström; Martin C Frith; Alistair Forrest; Wynand B Alkema; Sin Lam Tan; Charles Plessy; Rimantas Kodzius; Timothy Ravasi; Takeya Kasukawa; Shiro Fukuda; Mutsumi Kanamori-Katayama; Yayoi Kitazume; Hideya Kawaji; Chikatoshi Kai; Mari Nakamura; Hideaki Konno; Kenji Nakano; Salim Mottagui-Tabar; Peter Arner; Alessandra Chesi; Stefano Gustincich; Francesca Persichetti; Harukazu Suzuki; Sean M Grimmond; Christine A Wells; Valerio Orlando; Claes Wahlestedt; Edison Liu; Matthias Harbers; Jun Kawai; Vladimir Bajic; David A Hume; Yoshihide Hayashizaki
Genome-wide analysis of mammalian promoter architecture and evolution.
Nature genetics 2006;38(6):626-35.
2006: Edison Liu; Vladimir Kuznetsov; Lance D Miller
In the pursuit of complexity: systems medicine in cancer biology.
Cancer cell 2006;9(4):245-7.
2006: Chia-Lin Wei; Qiang Wu; Vinsensius B Vega; Kuo Ping Chiu; Patrick Ng; Tao Zhang; Atif Shahab; How Choong Yong; YuTao Fu; Zhiping Weng; JianJun Liu; Xiao Dong Zhao; Joon-Lin Chew; Yen Ling Lee; Vladimir Kuznetsov; Wing-Kin Sung; Lance D Miller; Bing Lim; Edison Liu; Qiang Yu; Huck-Hui Ng; Yijun Ruan
A global map of p53 transcription-factor binding sites in the human genome.
Cell 2006;124(1):207-19.
2006: Kristjana Einarsdóttir; Lena U Rosenberg; Keith Humphreys; Carine Bonnard; Juni Palmgren; Yuqing Li; Yi Li; Kee-Seng Chia; Edison Liu; Per Hall; Jianjun Liu; Sara Wedrén
Comprehensive analysis of the ATM, CHEK2 and ERBB2 genes in relation to breast tumour characteristics and survival: a population-based case-control and follow-up study.
Breast cancer research : BCR 2006;8(6):R67.
2006: Vinsensius B Vega; Chin-Yo Lin; Koon Siew Lai; Say Li Kong; Min Xie; Xiaodi Su; Huey Fang Teh; Jane S Thomsen; Ai Li Yeo; Wing-Kin Sung; Guillaume Bourque; Edison Liu
Multiplatform genome-wide identification and modeling of functional human estrogen receptor binding sites.
Genome biology 2006;7(9):R82.
2006: Stefano Calza; Per Hall; Gert Auer; Judith Bjöhle; Sigrid Klaar; Ulrike Kronenwett; Edison Liu; Lance Miller; Alexander Ploner; Johanna Smeds; Jonas Bergh; Yudi Pawitan
Intrinsic molecular signature of breast cancer in a population-based cohort of 412 patients.
Breast cancer research : BCR 2006;8(4):R34.
2006: Per Hall; Alexander Ploner; Judith Bjöhle; Fei Huang; Chin-Yo Lin; Edison Liu; Lance D Miller; Hans Nordgren; Yudi Pawitan; Peter Shaw; Lambert Skoog; Johanna Smeds; Sara Wedrén; John Ohd; Jonas Bergh
Hormone-replacement therapy influences gene expression profiles and is associated with breast-cancer prognosis: a cohort study.
BMC medicine 2006;4():16.
2006: Leonard Lipovich; Ravi Raj Vanisri; Say Li Kong; Chin-Yo Lin; Edison Liu
Primate-specific endogenous cis-antisense transcription in the human 5q31 protocadherin gene cluster.
Journal of molecular evolution 2006;62(1):73-88.
2006: Tao Zhang; Mya Breitbart; Wah Heng Lee; Jin-Quan Run; Chia-Lin Wei; Shirlena Wee Ling Soh; Martin L Hibberd; Edison Liu; Forest Rohwer; Yijun Ruan
RNA viral community in human feces: prevalence of plant pathogenic viruses.
PLoS biology 2006;4(1):e3.
2006: Siew Hong Lam; Yi Lian Wu; Vinsensius B Vega; Lance D Miller; Jan Spitsbergen; Yan Tong; Huiqing Zhan; Kunde R Govindarajan; Serene Lee; Sinnakarupan Mathavan; Karuturi R Krishna Murthy; Donald R Buhler; Edison Liu; Zhiyuan Gong
Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression.
Nature biotechnology 2006;24(1):73-5.
2005: Yan Zhao; Jing Tan; Li Zhuang; Xia Jiang; Edison Liu; Qiang Yu
Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(44):16090-5.
2005: Jing Tan; Li Zhuang; Hui-Sun Leong; N Gopalakrishna Iyer; Edison Liu; Qiang Yu
Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells.
Cancer research 2005;65(19):9012-20.
2005: Suk Woo Nam; Jik Young Park; Adaikalavan Ramasamy; Shirish Shevade; Amirul Islam; Philip M Long; Cheol Keun Park; Soo Eun Park; Su Young Kim; Sug Hyung Lee; Won Sang Park; Nam Jin Yoo; Edison Liu; Lance D Miller; Jung Young Lee
Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling.
Hepatology (Baltimore, Md.) 2005;42(4):809-18.
2005: Hong Lok Lung; Dhinoth Kumar Bangarusamy; Dan Xie; Arthur Kwok Leung Cheung; Yue Cheng; Mande Kuppusamy Kumaran; Lance Miller; Edison Liu; Xin-Yuan Guan; Jonathan S T Sham; Yan Fang; Liqiong Li; Nancy Wang; Alexei Protopopov; Eugene R Zabarovsky; Sai Wah Tsao; Eric J Stanbridge; Maria Li Lung
THY1 is a candidate tumour suppressor gene with decreased expression in metastatic nasopharyngeal carcinoma.
Oncogene 2005;24(43):6525-32.
2005: Lance D Miller; Johanna Smeds; joshy george; Vinsensius B Vega; Liza Vergara; Alexander Ploner; Yudi Pawitan; Per Hall; Sigrid Klaar; Edison Liu; Jonas Bergh
An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13550-5.
2005: piero carninci; T Kasukawa; S Katayama; J Gough; M C Frith; N Maeda; R Oyama; T Ravasi; B Lenhard; C Wells; R Kodzius; K Shimokawa; Vladimir Bajic; S E Brenner; S Batalov; Alistair Forrest; M Zavolan; M J Davis; L G Wilming; V Aidinis; J E Allen; A Ambesi-Impiombato; R Apweiler; R N Aturaliya; Timothy Lawrence Bailey; M Bansal; L Baxter; K W Beisel; Tom Bersano; H Bono; Alistair Chalk; K P Chiu; V Choudhary; A Christoffels; D R Clutterbuck; M L Crowe; E Dalla; B P Dalrymple; B de Bono; G Della Gatta; D di Bernardo; T Down; P Engstrom; M Fagiolini; G Faulkner; C F Fletcher; T Fukushima; M Furuno; S Futaki; manuela gariboldi; P Georgii-Hemming; Thomas Gingeras; Takashi Gojobori; R E Green; S Gustincich; M Harbers; Y Hayashi; T K Hensch; N Hirokawa; D Hill; L Huminiecki; M Iacono; Kazuho Ikeo; A Iwama; T Ishikawa; M Jakt; Alexander Kanapin; M Katoh; Y Kawasawa; J Kelso; H Kitamura; H Kitano; george kollias; S P T Krishnan; A Kruger; S K Kummerfeld; I V Kurochkin; L F Lareau; D Lazarevic; Leonard Lipovich; J Liu; S Liuni; S McWilliam; M Madan Babu; M Madera; LUIGI MARCHIONNI; H Matsuda; S Matsuzawa; H Miki; F Mignone; S Miyake; K Morris; S Mottagui-Tabar; N Mulder; N Nakano; H Nakauchi; P Ng; R Nilsson; S Nishiguchi; S Nishikawa; F Nori; O Ohara; Yasushi Okazaki; V Orlando; K C Pang; W J Pavan; G Pavesi; G Pesole; Nikolai Petrovsky; S Piazza; J Reed; J F Reid; B Z Ring; M Ringwald; B Rost; Y Ruan; Steven L Salzberg; A Sandelin; C Schneider; Christian Schönbach; K Sekiguchi; Colin Semple; S Seno; L Sessa; Y Sheng; Y Shibata; H Shimada; K Shimada; D Silva; B Sinclair; S Sperling; Elia Stupka; K Sugiura; R Sultana; Y Takenaka; K Taki; K Tammoja; S L Tan; S Tang; Martin Taylor; J Tegner; S A Teichmann; H R Ueda; E van Nimwegen; R Verardo; C L Wei; K Yagi; H Yamanishi; E Zabarovsky; S Zhu; A Zimmer; Winston Hide; Carol Bult; S M Grimmond; Rohan Teasdale; Edison Liu; V Brusic; John Quackenbush; Claes Wahlestedt; J S Mattick; D A Hume; C Kai; D Sasaki; Y Tomaru; S Fukuda; M Kanamori-Katayama; M Suzuki; J Aoki; T Arakawa; J Iida; K Imamura; Masayoshi Itoh; T Kato; Hideya Kawaji; N Kawagashira; T Kawashima; M Kojima; S Kondo; H Konno; K Nakano; N Ninomiya; T Nishio; M Okada; C Plessy; K Shibata; T Shiraki; S Suzuki; M Tagami; Kazunori Waki; A Watahiki; Y Okamura-Oho; H Suzuki; J Kawai; Y Hayashizaki
The transcriptional landscape of the mammalian genome.
Science (New York, N.Y.) 2005;309(5740):1559-63.
2005: Sinnakarupan Mathavan; Serene G P Lee; Alicia Mak; Lance D Miller; Karuturi R Krishna Murthy; Kunde R Govindarajan; Yan Tong; Yi Lian Wu; Siew Hong Lam; Henry Yang; Yijun Ruan; Vladimir Korzh; Zhiyuan Gong; Edison Liu; Thomas Lufkin
Transcriptome analysis of zebrafish embryogenesis using microarrays.
PLoS genetics 2005;1(2):260-76.
2005: George Reid; Raphaël Métivier; Chin-Yo Lin; Stefanie Denger; David Ibberson; Tomi Ivacevic; Heike Brand; Vladimir Benes; Edison Liu; Frank Gannon
Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor alpha, in response to deacetylase inhibition by valproic acid and trichostatin A.
Oncogene 2005;24(31):4894-907.
2005: Edison Liu
New technologies for high-throughput analysis.
Pharmacogenomics 2005;6(5):469-71.
2005: Lynn Dressler; Donald A Berry; Gloria Broadwater; David Cowan; Kelly Cox; Stephanie Griffin; Ashley Miller; Jessica Tse; Debra Novotny; Diane L Persons; Maurice Barcos; I Craig Henderson; Edison Liu; Ann D Thor; Daniel R Budman; Hyman Muss; Larry Norton; Daniel F Hayes
Comparison of HER2 status by fluorescence in situ hybridization and immunohistochemistry to predict benefit from dose escalation of adjuvant doxorubicin-based therapy in node-positive breast cancer patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(19):4287-97.
2005: Xiu Qin Xu; B Starling Emerald; Eyleen L K Goh; Nagarajan Kannan; Lance D Miller; Peter D Gluckman; Edison Liu; Peter E Lobie
Gene expression profiling to identify oncogenic determinants of autocrine human growth hormone in human mammary carcinoma.
The Journal of biological chemistry 2005;280(25):23987-4003.
2005: Edison Liu
Systems biology, integrative biology, predictive biology.
Cell 2005;121(4):505-6.
2005: Andrea Bimbó; Yonghui Jia; Siew Lay Poh; R Krishna Murthy Karuturi; Nicole R den Elzen; Xu Peng; Liling Zheng; Matthew O'Connell; Edison Liu; Mohan K Balasubramanian; Jianhua Liu
Systematic deletion analysis of fission yeast protein kinases.
Eukaryotic cell 2005;4(4):799-813.
2005: Edison Liu
Mechanism-derived gene expression signatures and predictive biomarkers in clinical oncology.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(10):3531-2.
2005: Xu Peng; R Krishna Murthy Karuturi; Lance D Miller; Kui Lin; Yonghui Jia; Pinar Kondu; Long Wang; Lim-Soon Wong; Edison Liu; Mohan K Balasubramanian; Jianhua Liu
Identification of cell cycle-regulated genes in fission yeast.
Molecular biology of the cell 2005;16(3):1026-42.
2005: HYUN JU KANG; Suk Woo Nam; Hyunki Kim; Hwanseok Rhee; Nam-Gyun Kim; Haeryoung Kim; Woo Jin Hyung; Sung Hoon Noh; Joo-Hang Kim; Chae-Ok Yun; Edison Liu; Hoguen Kim
Correlation of KIT and platelet-derived growth factor receptor alpha mutations with gene activation and expression profiles in gastrointestinal stromal tumors.
Oncogene 2005;24(6):1066-74.
2005: Edison Liu
Expression genomics and drug development: towards predictive pharmacology.
Briefings in functional genomics & proteomics 2005;3(4):303-21.
2005: Patrick Ng; Chia-Lin Wei; Wing-Kin Sung; Kuo Ping Chiu; Leonard Lipovich; Chin Chin Ang; Sanjay Gupta; Atif Shahab; Azmi Ridwan; Chee Hong Wong; Edison Liu; Yijun Ruan
Gene identification signature (GIS) analysis for transcriptome characterization and genome annotation.
Nature methods 2005;2(2):105-11.
2005: Jianjun Liu; Siew Lan Lim; Yijun Ruan; Ai Ee Ling; Lisa F P Ng; Christian Drosten; Edison Liu; Lawrence W Stanton; Martin L Hibberd
SARS transmission pattern in Singapore reassessed by viral sequence variation analysis.
PLoS medicine 2005;2(2):e43.
2005: Chia-Lin Wei; Takumi Miura; Paul Robson; Sai-Kiang Lim; Xiu-Qin Xu; Mathia Yu-Chuan Lee; Sanjay Gupta; Lawrence W Stanton; Yongquan Luo; Jacqui Schmitt; Scott Thies; Wei Wang; Irina Khrebtukova; Daixing Zhou; Edison Liu; Yi Jun Ruan; Mahendra S Rao; Bing Lim
Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state.
Stem cells (Dayton, Ohio) 2005;23(2):166-85.
2005: Yudi Pawitan; Judith Bjöhle; Lukas Amler; Anna-Lena Borg; Suzanne Egyhazi; Per Hall; Xia Han; Lars Holmberg; Fei Huang; Sigrid Klaar; Edison Liu; Lance Miller; Hans Nordgren; Alexander Ploner; Kerstin Sandelin; Peter M Shaw; Johanna Smeds; Lambert Skoog; Sara Wedrén; Jonas Bergh
Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts.
Breast cancer research : BCR 2005;7(6):R953-64.
2005: Johanna Smeds; Lance D Miller; Judith Bjöhle; Per Hall; Sigrid Klaar; Edison Liu; Yudi Pawitan; Alexander Ploner; Jonas Bergh
Gene profile and response to treatment.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16 Suppl 2():ii195-202.
2005: Edison Liu
Genomic technologies and the interrogation of the transcriptome.
Mechanisms of ageing and development 2005;126(1):153-9.
2004: Knut R Steffensen; Soek Ying Neo; Thomas M Stulnig; Vinsensius B Vega; Safia S Rahman; Gertrud U Schuster; Jan-�ke GUSTAFSSON; Edison Liu
Genome-wide expression profiling; a panel of mouse tissues discloses novel biological functions of liver X receptors in adrenals.
Journal of molecular endocrinology 2004;33(3):609-22.
2004: Edison Liu
Expression genomics and cancer biology.
Pharmacogenomics 2004;5(8):1117-28.
2004: Hong Lok Lung; Yue Cheng; Mande Kuppusamy Kumaran; Edison Liu; Yoshinori Murakami; Cheuk Yu Chan; Wing Lung Yau; Josephine Mun Yee Ko; Eric J Stanbridge; Maria Li Lung
Fine mapping of the 11q22-23 tumor suppressive region and involvement of TSLC1 in nasopharyngeal carcinoma.
International journal of cancer. Journal international du cancer 2004;112(4):628-35.
2004: Zhen Wang; Yuqing Li; Edison Liu; Qiang Yu
Susceptibility to cell death induced by blockade of MAPK pathway in human colorectal cancer cells carrying Ras mutations is dependent on p53 status.
Biochemical and biophysical research communications 2004;322(2):609-13.
2004: Lisa F P Ng; Martin L Hibberd; Eng Eong Ooi; Kin Fai Tang; Soek Ying Neo; Jenny Tan; Karuturi R Krishna Murthy; Vinsensius B Vega; Jer-Ming Chia; Edison Liu; Ee Chee Ren
A human in vitro model system for investigating genome-wide host responses to SARS coronavirus infection.
BMC infectious diseases 2004;4():34.
2004: Vinsensius B Vega; Yijun Ruan; Jianjun Liu; Wah Heng Lee; Chia-Lin Wei; Su Yun Se Thoe; Kin Fai Tang; Tao Zhang; Prasanna R Kolatkar; Eng Eong Ooi; Ai Ee Ling; Lawrence W Stanton; Philip M Long; Edison Liu
Mutational dynamics of the SARS coronavirus in cell culture and human populations isolated in 2003.
BMC infectious diseases 2004;4():32.
2004: Ting Hu Qiu; Gadisetti V R Chandramouli; Kent W Hunter; Nawal W Alkharouf; Jeffrey E Green; Edison Liu
Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice: correlation to human disease.
Cancer research 2004;64(17):5973-81.
2004: Michael Welsh; Charlotte Welsh; Maria Ekman; Johan Dixelius; Robert Hägerkvist; Cecilia Annerén; Björn Akerblom; Siavosh Mahboobi; Subhashini Chandrasekharan; Edison Liu
The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity.
The Biochemical journal 2004;382(Pt 1):261-8.
2004: Chia-Lin Wei; Patrick Ng; Kuo Ping Chiu; Chee Hong Wong; Chin Chin Ang; Leonard Lipovich; Edison Liu; Yijun Ruan
5' Long serial analysis of gene expression (LongSAGE) and 3' LongSAGE for transcriptome characterization and genome annotation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11701-6.
2004: Vinsensius B Vega; Dhinoth Kumar Bangarusamy; Lance D Miller; Edison Liu; Chin-Yo Lin
BEARR: Batch Extraction and Analysis of cis-Regulatory Regions.
Nucleic acids research 2004;32(Web Server issue):W257-60.
2004: Paula M Gilmore; Nuala McCabe; Jennifer E Quinn; Richard D Kennedy; Julia J Gorski; Heather N Andrews; Stewart McWilliams; Michael Carty; Paul B Mullan; W Paul Duprex; Edison Liu; Patrick G Johnston; D Paul Harkin
BRCA1 interacts with and is required for paclitaxel-induced activation of mitogen-activated protein kinase kinase kinase 3.
Cancer research 2004;64(12):4148-54.
2004: Patricia S Kho; Zhen Wang; Li Zhuang; Yuqing Li; Joon-Lin Chew; Huck-Hui Ng; Edison Liu; Qiang Yu
p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis.
The Journal of biological chemistry 2004;279(20):21183-92.
2004: Edison Liu; Krishna R Karuturi
Microarrays and clinical investigations.
The New England journal of medicine 2004;350(16):1595-7.
2004: Soek Ying Neo; Chon Kar Leow; Vinsensius B Vega; Philip M Long; Amirul F M Islam; Paul B S Lai; Edison Liu; Ee Chee Ren
Identification of discriminators of hepatoma by gene expression profiling using a minimal dataset approach.
Hepatology (Baltimore, Md.) 2004;39(4):944-53.
2004: Christopher W Wong; Thomas J Albert; Vinsensius B Vega; Jason E Norton; David J Cutler; Richmond Todd; Lawrence W Stanton; Edison Liu; Lance D Miller
Tracking the evolution of the SARS coronavirus using high-throughput, high-density resequencing arrays.
Genome research 2004;14(3):398-405.
2004: Maria Rosa Bani; Maria Ines Nicoletti; Nawal W Alkharouf; Carmen Ghilardi; David Petersen; Eugenio Erba; Edward A Sausville; Edison Liu; Raffaella Giavazzi
Gene expression correlating with response to paclitaxel in ovarian carcinoma xenografts.
Molecular cancer therapeutics 2004;3(2):111-21.
2004: Lance Miller; Edison Liu
Expression profiling and breast cancer biology.
Breast disease 2004;19():29-34.
2004: Chin-Yo Lin; Anders Ström; Vinsensius B Vega; Say Li Kong; Ai Li Yeo; Jane S Thomsen; Wan Ching Chan; Balraj Doray; Dhinoth Kumar Bangarusamy; Adaikalavan Ramasamy; Liza A Vergara; Suisheng Tang; Allen Chong; Vladimir Bajic; Lance D Miller; Jan-�ke GUSTAFSSON; Edison Liu
Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells.
Genome biology 2004;5(9):R66.
2004: Lance D Miller; Peter McPhie; Hideyo Suzuki; Yasuhito Kato; Edison Liu; Sheue-Yann Cheng
Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance.
Genome biology 2004;5(5):R31.
2004: Edison Liu
Representational oligonucleotide microarray analysis (ROMA) in pharmacogenomics.
The pharmacogenomics journal 2004;4(2):74-6.
2004: Lisa F P Ng; Michelle Wong; Susie Koh; Eng Eong Ooi; Kin Fai Tang; Hoe Nam Leong; Ai Ee Ling; Lora V Agathe; Jenny Tan; Edison Liu; Ee Chee Ren; Lee-Ching Ng; Martin L Hibberd
Detection of severe acute respiratory syndrome coronavirus in blood of infected patients.
Journal of clinical microbiology 2004;42(1):347-50.
2004: Yijun Ruan; Pierre Le Ber; Huck-Hui Ng; Edison Liu
Interrogating the transcriptome.
Trends in biotechnology 2004;22(1):23-30.
2003: Tero A H Järvinen; Edison Liu
Topoisomerase IIalpha gene (TOP2A) amplification and deletion in cancer--more common than anticipated.
Cytopathology : official journal of the British Society for Clinical Cytology 2003;14(6):309-13.
2003: Christos Sotiriou; Soek Ying Neo; Lisa M McShane; Edward L Korn; Philip M Long; Amir A Jazaeri; Philippe Martiat; Steve B Fox; Adrian L Harris; Edison Liu
Breast cancer classification and prognosis based on gene expression profiles from a population-based study.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(18):10393-8.
2003: Tero A H Järvinen; Edison Liu
HER-2/neu and topoisomerase IIalpha--simultaneous drug targets in cancer.
Combinatorial chemistry & high throughput screening 2003;6(5):455-70.
2003: Edison Liu; Harvey E L Teo; W C G Peh
Clinics in diagnostic imaging (87). Subcutaneous lipoma.
Singapore medical journal 2003;44(7):375-9.
2003: Vladimir Bajic; Sin Lam Tan; Allen Chong; Suisheng Tang; Anders Ström; Jan-�ke GUSTAFSSON; Chin-Yo Lin; Edison Liu
Dragon ERE Finder version 2: A tool for accurate detection and analysis of estrogen response elements in vertebrate genomes.
Nucleic acids research 2003;31(13):3605-7.
2003: Matthias G O Lorenz; Lizette M Cortes; Juergen J Lorenz; Edison Liu
Strategy for the design of custom cDNA microarrays.
BioTechniques 2003;34(6):1264-70.
2003: Edison Liu
Molecular oncodiagnostics: where we are and where we need to go.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(11):2052-5.
2003: Yi Jun Ruan; Chia-Lin Wei; Ai Ling Ee; Vinsensius B Vega; Herve Thoreau; Se Thoe Yun Su; Jer-Ming Chia; Patrick Ng; Kuo Ping Chiu; Landri Lim; Tao Zhang; Chan Kwai Peng; Ean Oon Lynette Lin; Ng Mah Lee; Sin Leo Yee; Lisa F P Ng; Ren Ee Chee; Lawrence W Stanton; Philip M Long; Edison Liu
Comparative full-length genome sequence analysis of 14 SARS coronavirus isolates and common mutations associated with putative origins of infection.
Lancet 2003;361(9371):1779-85.
2003: Kent Hunter; Danny R Welch; Edison Liu
Genetic background is an important determinant of metastatic potential.
Nature genetics 2003;34(1):23-4; author reply 25.
2003: Tero A H Järvinen; Edison Liu
HER-2/neu and topoisomerase IIalpha in breast cancer.
Breast cancer research and treatment 2003;78(3):299-311.
2003: Tanya K Meyer; LiHui Xu; Jinli Chang; Edison Liu; Rolf J Craven; William G Cance
Breast cancer cell line proliferation blocked by the Src-related Rak tyrosine kinase.
International journal of cancer. Journal international du cancer 2003;104(2):139-46.
2003: Lajos Pusztai; Christos Sotiriou; Thomas Buchholz; Funda Meric; W Fraser Symmans; Francisco J Esteva; Aysegul Sahin; Edison Liu; Gabriel N Hortobagi
Molecular profiles of invasive mucinous and ductal carcinomas of the breast: a molecular case study.
Cancer genetics and cytogenetics 2003;141(2):148-53.
2003: Edison Liu
Classification of cancers by expression profiling.
Current opinion in genetics & development 2003;13(1):97-103.
2003: Amir A Jazaeri; Karen Lu; Rosemarie Schmandt; Charles P Harris; Pulivarthi H Rao; Christos Sotiriou; Gadisetti V R Chandramouli; David M Gershenson; Edison Liu
Molecular determinants of tumor differentiation in papillary serous ovarian carcinoma.
Molecular carcinogenesis 2003;36(2):53-9.
2003: Edison Liu
General keynote: expression profiling and the study of ovarian cancer.
Gynecologic oncology 2003;88(1 Pt 2):S14-5; discussion S22-4.
2002: Lance D Miller; Philip M Long; Limsoon Wong; Sayan Mukherjee; Lisa M McShane; Edison Liu
Optimal gene expression analysis by microarrays.
Cancer cell 2002;2(5):353-61.
2002: Yao-Yu Eric Chuang; Yidong Chen; V R Chandramouli; John A Cook; Deborah Coffin; Mong-Hsun Tsai; William DeGraff; Hailing Yan; Shuping Zhao; Angelo Russo; Edison Liu; James B Mitchell
Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells.
Cancer research 2002;62(21):6246-54.
2002: Renae L Malek; Rosalyn B Irby; Qingbin M Guo; Kerry Lee; Sylvia Wong; Mei He; Jennifer Tsai; Bryan Frank; Edison Liu; John Quackenbush; Richard Jove; Timothy J Yeatman; Norman H Lee
Identification of Src transformation fingerprint in human colon cancer.
Oncogene 2002;21(47):7256-65.
2002: Liang Shan; Mei He; Minshu Yu; Cunping Qiu; Norman H Lee; Edison Liu; Elizabeth G Snyderwine
cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene.
Carcinogenesis 2002;23(10):1561-8.
2002: TG Zogakis; Nick G Costouros; Erwin A Kruger; S Forbes; M He; M Qian; Andrew L Feldman; William D Figg; H Richard Alexander; Edison Liu; E C Kohn; Steven Libutti
Microarray gene expression profiling of angiogenesis inhibitors using the rat aortic ring assay.
BioTechniques 2002;33(3):664-6, 668, 670.
2002: Amir A Jazaeri; Cindy J Yee; Christos Sotiriou; Kelly R Brantley; Jeff Boyd; Edison Liu
Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers.
Journal of the National Cancer Institute 2002;94(13):990-1000.
2002: Ena Wang; Lance D Miller; Galen A Ohnmacht; Simone Mocellin; Ainhoa Perez-Diez; David Petersen; Yingdong Zhao; Richard Simon; John I Powell; Esther Asaki; H Richard Alexander; Paul H Duray; Meenhard Herlyn; Nicholas P Restifo; Edison Liu; STEVEN ROSENBERG; Francesco M Marincola
Prospective molecular profiling of melanoma metastases suggests classifiers of immune responsiveness.
Cancer research 2002;62(13):3581-6.
2002: Subhashini Chandrasekharan; Ting Hu Qiu; Nawal W Alkharouf; Kelly Brantley; James B Mitchell; Edison Liu
Characterization of mice deficient in the Src family nonreceptor tyrosine kinase Frk/rak.
Molecular and cellular biology 2002;22(14):5235-47.
2002: Diana Cozma; Luanne Lukes; Jessica Rouse; Ting Hu Qiu; Edison Liu; Kent W Hunter
A bioinformatics-based strategy identifies c-Myc and Cdc25A as candidates for the Apmt mammary tumor latency modifiers.
Genome research 2002;12(6):969-75.
2002: Kartiki V Desai; Nianqing Xiao; Weili Wang; Lisa Gangi; John Greene; John I Powell; Robert Dickson; Priscilla A Furth; Kent Hunter; Raju Kucherlapati; Richard Simon; Edison Liu; Jeffrey E Green
Initiating oncogenic event determines gene-expression patterns of human breast cancer models.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):6967-72.
2002: Mary E Edgerton; Ronald Taylor; John I Powell; Lawrence Hunter; Richard Simon; Edison Liu
A bioinformatics tool to select sequences for microarray studies of mouse models of oncogenesis.
Bioinformatics (Oxford, England) 2002;18(5):774-5.
2002: Qiang Yu; Mei He; Norman H Lee; Edison Liu
Identification of Myc-mediated death response pathways by microarray analysis.
The Journal of biological chemistry 2002;277(15):13059-66.
2002: Kathleen Dorsey; Sharon N Edmiston; Lisa Cui; S Scott Drouin; Jingzhong Pang; Mei He; Chiu-Kit Tse; Joseph Geradts; Lynn Dressler; Edison Liu; Robert C Millikan; Beth Newman
Prevalence and spectrum of p53 mutations associated with smoking in breast cancer.
Cancer research 2002;62(7):1987-95.
2002: Yi Zhou; Fuad G Gwadry; William C Reinhold; Lance D Miller; Lawrence H Smith; Uwe Scherf; Edison Liu; Kurt W Kohn; Yves Pommier; John N Weinstein
Transcriptional regulation of mitotic genes by camptothecin-induced DNA damage: microarray analysis of dose- and time-dependent effects.
Cancer research 2002;62(6):1688-95.
2002: Laura Assersohn; Lisa Gangi; Yingdong Zhao; Mitch Dowsett; Richard Simon; Trevor J Powles; Edison Liu
The feasibility of using fine needle aspiration from primary breast cancers for cDNA microarray analyses.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(3):794-801.
2002: Christos Sotiriou; Chand Khanna; Amir A Jazaeri; David Petersen; Edison Liu
Core biopsies can be used to distinguish differences in expression profiling by cDNA microarrays.
The Journal of molecular diagnostics : JMD 2002;4(1):30-6.
2002: Philippe C Bishop; Timothy Myers; Robert W Robey; David W Fry; Edison Liu; Mikhail V Blagosklonny; Susan E Bates
Differential sensitivity of cancer cells to inhibitors of the epidermal growth factor receptor family.
Oncogene 2002;21(1):119-27.
2002: Edison Liu; C Sotiriou
Defining the galaxy of gene expression in breast cancer.
Breast cancer research : BCR 2002;4(4):141-4.
2002: Christos Sotiriou; Trevor J Powles; Mitch Dowsett; Amir A Jazaeri; Andrew L Feldman; Laura Assersohn; Chandramouli Gadisetti; Steven Libutti; Edison Liu
Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer.
Breast cancer research : BCR 2002;4(3):R3.
2001: L D Miller; KS Park; Qingbin M Guo; Nawal W Alkharouf; Renae L Malek; Norman H Lee; Edison Liu; Sheue-Yann Cheng
Silencing of Wnt signaling and activation of multiple metabolic pathways in response to thyroid hormone-stimulated cell proliferation.
Molecular and cellular biology 2001;21(19):6626-39.
2001: Y Terry Lee; L D Miller; AN Gubin; F Makhlouf; Urszula Wojda; A John Barrett; Edison Liu; Jeffery L Miller
Transcription patterning of uncoupled proliferation and differentiation in myelodysplastic bone marrow with erythroid-focused arrays.
Blood 2001;98(6):1914-21.
2001: Olga Aprelikova; Amy J Pace; Bingliang Fang; Beverly H Koller; Edison Liu
BRCA1 is a selective co-activator of 14-3-3 sigma gene transcription in mouse embryonic stem cells.
The Journal of biological chemistry 2001;276(28):25647-50.
2001: Gang Dong; E Loukinova; Zhong Chen; L Gangi; T I Chanturita; Edison Liu; Carter Van Waes
Molecular profiling of transformed and metastatic murine squamous carcinoma cells by differential display and cDNA microarray reveals altered expression of multiple genes related to growth, apoptosis, angiogenesis, and the NF-kappaB signal pathway.
Cancer research 2001;61(12):4797-808.
2001: Mel Campbell; Olga Aprelikova; Riet Van Der Meer; Randall L Woltjer; Cindy J Yee; Edison Liu; Roy A Jensen
Construction and characterization of recombinant adenoviruses expressing human BRCA1 or murine Brca1 genes.
Cancer gene therapy 2001;8(3):231-9.
2001: K Gardner; Edison Liu
BRCA1 function in T lymphocytes: a cellular specificity of a different kind.
Breast cancer research : BCR 2001;3(1):11-3.
2000: Qingbin M Guo; Renae L Malek; Sohyoung Kim; C Chiao; M He; M Ruffy; K Sanka; Norman H Lee; Chi Dang; Edison Liu
Identification of c-myc responsive genes using rat cDNA microarray.
Cancer research 2000;60(21):5922-8.
2000: Donald A Berry; Hyman Muss; Ann D Thor; Lynn Dressler; Edison Liu; Gloria Broadwater; Daniel R Budman; I Craig Henderson; Maurice Barcos; Daniel F Hayes; Larry Norton
HER-2/neu and p53 expression versus tamoxifen resistance in estrogen receptor-positive, node-positive breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(20):3471-9.
2000: Ena Wang; L D Miller; Galen A Ohnmacht; Edison Liu; Francesco M Marincola
High-fidelity mRNA amplification for gene profiling.
Nature biotechnology 2000;18(4):457-9.
2000: S Paik; Edison Liu
HER2 as a predictor of therapeutic response in breast cancer.
Breast disease 2000;11():91-102.
2000: Edison Liu
Breast cancer research: where we are and where we should go.
Breast cancer research : BCR 2000;2(2):73-6.
2000: W Y Huang; Beth Newman; Robert C Millikan; Kathleen Dorsey; Barbara S Hulka; Michael J Schell; Edison Liu
Risk of breast cancer according to the status of HER-2/neu oncogene amplification.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000;9(1):65-71.
2000: A Stark; Barbara S Hulka; S Joens; D Novotny; Ann D Thor; L E Wold; Michael J Schell; Joseph L Melton; Edison Liu; Kathleen Dorsey
HER-2/neu amplification in benign breast disease and the risk of subsequent breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(2):267-74.
1999: Wei-Ping Lee; Yong Liao; D Robinson; Hsing-Jien Kung; Edison Liu; Mien-Chie Hung
Axl-gas6 interaction counteracts E1A-mediated cell growth suppression and proapoptotic activity.
Molecular and cellular biology 1999;19(12):8075-82.
1999: Olga Aprelikova; Bingliang Fang; E G Meissner; S Cotter; Mel Campbell; A Kuthiala; M Bessho; Roy A Jensen; Edison Liu
BRCA1-associated growth arrest is RB-dependent.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(21):11866-71.
1999: Wendell G Yarbrough; Robert A Buckmire; M Bessho; Edison Liu
Biologic and biochemical analyses of p16(INK4a) mutations from primary tumors.
Journal of the National Cancer Institute 1999;91(18):1569-74.
1999: Y Li; Robert C Millikan; Beth Newman; Kathleen Dorsey; Chiu-Kit Tse; Edison Liu
P57 (KIP2) polymorphisms and breast cancer risk.
Human genetics 1999;104(1):83-8.
1998: J Zujewski; Edison Liu
The 1998 St. Gallen's Consensus Conference: an assessment.
Journal of the National Cancer Institute 1998;90(21):1587-9.
1998: Ann D Thor; Donald A Berry; Daniel R Budman; Hyman Muss; T Kute; I Craig Henderson; Maurice Barcos; Constance Cirrincione; Susan M Edgerton; C Allred; Larry Norton; Edison Liu
erbB-2, p53, and efficacy of adjuvant therapy in lymph node-positive breast cancer.
Journal of the National Cancer Institute 1998;90(18):1346-60.
1998: Q Guo; J Xie; Chi Dang; Edison Liu; John M Bishop
Identification of a large Myc-binding protein that contains RCC1-like repeats.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9172-7.
1998: A Burchert; EC Attar; P McCloskey; YW Fridell; Edison Liu
Determinants for transformation induced by the Axl receptor tyrosine kinase.
Oncogene 1998;16(24):3177-87.
1998: George R Honig; C R Suarez; Loyda Vida; Shijiang Lu; Edison Liu
Juvenile myelomonocytic leukemia (JMML) with the hematologic phenotype of severe beta thalassemia.
American journal of hematology 1998;58(1):67-71.
1998: B Newman; Edison Liu
Perspective on BRCA1.
Breast disease 1998;10(1-2):3-10.
1998: Edison Liu
Breast disease. Introduction.
Breast disease 1998;10(1-2):2.
1998: YW Fridell; J Villa; EC Attar; Edison Liu
GAS6 induces Axl-mediated chemotaxis of vascular smooth muscle cells.
The Journal of biological chemistry 1998;273(12):7123-6.
1997: P McCloskey; YW Fridell; EC Attar; J Villa; Y Jin; B Varnum; Edison Liu
GAS6 mediates adhesion of cells expressing the receptor tyrosine kinase Axl.
The Journal of biological chemistry 1997;272(37):23285-91.
1997: Richard F Loeser; B C Varnum; Cathy S Carlson; M B Goldring; Edison Liu; S Sadiev; Timothy E Kute; R Wallin
Human chondrocyte expression of growth-arrest-specific gene 6 and the tyrosine kinase receptor axl: potential role in autocrine signaling in cartilage.
Arthritis and rheumatism 1997;40(8):1455-65.
1996: O Aprelikova; A Kuthiala; M Bessho; Stephen Ethier; Edison Liu
BRCA1 protein level is not affected by peptide growth factors in MCF10A cell line.
Oncogene 1996;13(11):2487-91.
1996: Wendell G Yarbrough; O Aprelikova; H Pei; Andrew F Olshan; Edison Liu
Familial tumor syndrome associated with a germline nonfunctional p16INK4a allele.
Journal of the National Cancer Institute 1996;88(20):1489-91.
1996: Kathleen Dorsey; S N Edmiston; Barbara S Hulka; P A Garrett; Edison Liu
Internal sequence variations in the Ha-ras variable number tandem repeat rare and common alleles identified by minisatellite variant repeat polymerase chain reaction.
Cancer research 1996;56(20):4773-7.
1996: L H Xu; L V Owens; G C Sturge; X Yang; Edison Liu; Rolf J Craven; William G Cance
Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(4):413-8.
1996: Y W Fridell; Y Jin; Lawrence A Quilliam; A Burchert; P McCloskey; G Spizz; B Varnum; Channing J Der; Edison Liu
Differential activation of the Ras/extracellular-signal-regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinase.
Molecular and cellular biology 1996;16(1):135-45.
1995: K S Lai; Y Jin; Douglas K. Graham; bruce witthuhn; J N Ihle; Edison Liu
A kinase-deficient splice variant of the human JAK3 is expressed in hematopoietic and epithelial cancer cells.
The Journal of biological chemistry 1995;270(42):25028-36.
1995: Rolf J Craven; William G Cance; Edison Liu
The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb.
Cancer research 1995;55(18):3969-72.
1995: O Aprelikova; Yue Xiong; Edison Liu
Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase.
The Journal of biological chemistry 1995;270(31):18195-7.
1995: L V Owens; L Xu; Rolf J Craven; Georgette Dent; Timothy Weiner; L Kornberg; Edison Liu; William G Cance
Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors.
Cancer research 1995;55(13):2752-5.
1995: Kathleen Dorsey; S Edmiston; D B Fried; Barbara S Hulka; P A Garrett; Edison Liu
Ha-ras rare alleles in breast cancer susceptibility.
Breast cancer research and treatment 1995;35(1):97-104.
1995: Beth Newman; Patricia G Moorman; Robert C Millikan; Bahjat F Qaqish; Joseph Geradts; T E Aldrich; Edison Liu
The Carolina Breast Cancer Study: integrating population-based epidemiology and molecular biology.
Breast cancer research and treatment 1995;35(1):51-60.
1995: M Sorensen; Edison Liu
With a different voice: integrating the psychosocial perspective into routine oncology care.
Breast cancer research and treatment 1995;35(1):39-42.
1995: William G Cance; Edison Liu
Protein kinases in human breast cancer.
Breast cancer research and treatment 1995;35(1):105-14.
1995: Edison Liu
The specialized program of research excellence in breast cancer at the University of North Carolina at Chapel Hill.
Breast cancer research and treatment 1995;35(1):1-5.
1995: K A Augustine; Edison Liu; Thomas W Sadler
Antisense inhibition of engrailed genes in mouse embryos reveals roles for these genes in craniofacial and neural tube development.
Teratology 1995;51(5):300-10.
1995: Thomas W Sadler; Edison Liu; K A Augustine
Antisense targeting of engrailed-1 causes abnormal axis formation in mouse embryos.
Teratology 1995;51(5):292-9.
1995: Rolf J Craven; L H Xu; Timothy Weiner; Y W Fridell; Georgette Dent; S Srivastava; B Varnum; Edison Liu; William G Cance
Receptor tyrosine kinases expressed in metastatic colon cancer.
International journal of cancer. Journal international du cancer 1995;60(6):791-7.
1995: K A Augustine; Edison Liu; Thomas W Sadler
Interactions of Wnt-1 and Wnt-3a are essential for neural tube patterning.
Teratology 1995;51(2):107-19.
1995: John P O'Bryan; Y W Fridell; R Koski; B Varnum; Edison Liu
The transforming receptor tyrosine kinase, Axl, is post-translationally regulated by proteolytic cleavage.
The Journal of biological chemistry 1995;270(2):551-7.
1995: B L Weber; R M Giusti; Edison Liu
Developing strategies for intervention and prevention in hereditary breast cancer.
Journal of the National Cancer Institute. Monographs 1995;(17):99-102.
1994: William G Cance; Rolf J Craven; M Bergman; L Xu; K Alitalo; Edison Liu
Rak, a novel nuclear tyrosine kinase expressed in epithelial cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(12):1347-55.
1994: P McCloskey; J Pierce; R A Koski; B Varnum; Edison Liu
Activation of the Axl receptor tyrosine kinase induces mitogenesis and transformation in 32D cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(10):1105-17.
1994: B S Hulka; Edison Liu; Ruth A Lininger
Steroid hormones and risk of breast cancer.
Cancer 1994;74(3 Suppl):1111-24.
1994: bruce witthuhn; O Silvennoinen; Osamu Miura; K S Lai; C Cwik; Edison Liu; James N Ihle
Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells.
Nature 1994;370(6485):153-7.
1994: Hyman Muss; Ann D Thor; D A Berry; Timothy E Kute; Edison Liu; F Koerner; Constance Cirrincione; D R Budman; W C Wood; M Barcos
c-erbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancer.
The New England journal of medicine 1994;330(18):1260-6.
1994: Christian A Schmidt; Andreas Neubauer; K H Seeger; Christoph Rochlitz; T Binder; Helmut Oettle; G Henze; Edison Liu; Dieter Huhn; Wolfgang Siegert
Detection of allelic loss within the beta 1-interferon gene in childhood acute lymphoblastic leukemia using differential PCR.
Annals of hematology 1994;68(4):171-4.
1994: Timothy Weiner; Edison Liu; Rolf J Craven; William G Cance
Expression of growth factor receptors, the focal adhesion kinase, and other tyrosine kinases in human soft tissue tumors.
Annals of surgical oncology 1994;1(1):18-27.
1993: Edison Liu
From the molecule to public health.
The New England journal of medicine 1993;329(27):2028-9.
1993: Timothy Weiner; Edison Liu; Rolf J Craven; William G Cance
Expression of focal adhesion kinase gene and invasive cancer.
Lancet 1993;342(8878):1024-5.
1993: Peter Effert; R H McCoy; P J Walther; Edison Liu
p53 gene alterations in human prostate carcinoma.
The Journal of urology 1993;150(1):257-61.
1993: A Neubauer; John P O'Bryan; A Fiebeler; C Schmidt; D Huhn; Edison Liu
Axl, a novel receptor tyrosine kinase isolated from chronic myelogenous leukemia.
Seminars in hematology 1993;30(3 Suppl 3):34.
1993: William G Cance; Rolf J Craven; T M Weiner; Edison Liu
Novel protein kinases expressed in human breast cancer.
International journal of cancer. Journal international du cancer 1993;54(4):571-7.
1993: J A Taylor; Allen J Wilcox; W A Bowes; Y Li; Edison Liu; M You
Risk of miscarriage and a common variant of the estrogen receptor gene.
American journal of epidemiology 1993;137(12):1361-4.
1993: A Neubauer; M He; C A Schmidt; D Huhn; Edison Liu
Genetic alterations in the p53 gene in the blast crisis of chronic myelogenous leukemia: analysis by polymerase chain reaction based techniques.
Leukemia 1993;7(4):593-600.
1993: Edison Liu; M He; U Rajgopal
Differential polymerase chain reaction in the analysis of gene dosage.
Seminars in cancer biology 1993;4(1):47-58.
1993: K Augustine; Edison Liu; Thomas W Sadler
Antisense attenuation of Wnt-1 and Wnt-3a expression in whole embryo culture reveals roles for these genes in craniofacial, spinal cord, and cardiac morphogenesis.
Developmental genetics 1993;14(6):500-20.
1993: Edison Liu
Oncogenes, breast cancer, and chemoprevention.
Journal of cellular biochemistry. Supplement 1993;17G():161-6.
1992: E N Levedakou; T G Strohmeyer; Peter Effert; Edison Liu
Expression of the matrix Gla protein in urogenital malignancies.
International journal of cancer. Journal international du cancer 1992;52(4):534-7.
1992: John S Wiener; Edison Liu; P J Walther
Oncogenic human papillomavirus type 16 is associated with squamous cell cancer of the male urethra.
Cancer research 1992;52(18):5018-23.
1992: William G Cance; Rolf J Craven; Edison Liu
Expression polymerase chain reaction: a sensitive method for analysis of gene expression in human tumours.
Surgical oncology 1992;1(4):309-14.
1992: John S Wiener; Peter Effert; P A Humphrey; L Yu; Edison Liu; P J Walther
Prevalence of human papillomavirus types 16 and 18 in squamous-cell carcinoma of the penis: a retrospective analysis of primary and metastatic lesions by differential polymerase chain reaction.
International journal of cancer. Journal international du cancer 1992;50(5):694-701.
1992: Peter Effert; A Neubauer; P J Walther; Edison Liu
Alterations of the P53 gene are associated with the progression of a human prostate carcinoma.
The Journal of urology 1992;147(3 Pt 2):789-93.
1992: Peter Effert; R A Frye; A Neubauer; Edison Liu; P J Walther
Human papillomavirus types 16 and 18 are not involved in human prostate carcinogenesis: analysis of archival human prostate cancer specimens by differential polymerase chain reaction.
The Journal of urology 1992;147(1):192-6.
1991: John P O'Bryan; R A Frye; Patricia C Cogswell; A Neubauer; B Kitch; C Prokop; R Espinosa; Michelle M Le Beau; Henry Earp; Edison Liu
axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.
Molecular and cellular biology 1991;11(10):5016-31.
1990: Edison Liu
The role of ras gene mutations in myeloproliferative disorders.
Clinics in laboratory medicine 1990;10(4):797-807.
1986: Edison Liu; C A Linker; Marc Shuman
Management of treatment failures in thrombotic thrombocytopenic purpura.
American journal of hematology 1986;23(4):347-61.
1985: P A Schneider; A A Rayner; C A Linker; M A Schuman; Edison Liu; D C Hohn
The role of splenectomy in multimodality treatment of thrombotic thrombocytopenic purpura.
Annals of surgery 1985;202(3):318-22.
1983: Edison Liu; M R Bristow; M J Stone; J T Willerson
Serum myoglobin, ionized calcium, and parathyroid function during rhabdomyolysis.
Archives of internal medicine 1983;143(1):154-7.