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David James

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Annette M Shewan; Laura Stirrat; Suzie Verma; Iain S Adamson; David E James; Dimitrios Kioumourtzoglou; Christopher A Lamb; Rebecca K McCann; Nia J Bryant
Endosomal sorting of GLUT4 and Gap1 is conserved between yeast and insulin-sensitive cells.
James G Burchfield; Daniel J Fazakerley; Weiping Han; William E Hughes; Jinling Lu; Katarina Mele; Yvonne Ng; Shi-Xiong Tan; Michael J Buckley; David E James
Novel systems for dynamically assessing insulin action in live cells reveals heterogeneity in the insulin response.
Tristan J Iseli; David E James; Edward W Kraegen; Nigel Turner; Sheng Yao; Yang Ye; Zeng C; Gregory J Cooney; Ji-Ming Ye
Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKβ.

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2013: Annette M Shewan; Laura Stirrat; Suzie Verma; Iain S Adamson; David E James; Dimitrios Kioumourtzoglou; Christopher A Lamb; Rebecca K McCann; Nia J Bryant
Endosomal sorting of GLUT4 and Gap1 is conserved between yeast and insulin-sensitive cells.
Journal of cell science 2013;126(Pt 7):1576-82.
2013: James G Burchfield; Daniel J Fazakerley; Weiping Han; William E Hughes; Jinling Lu; Katarina Mele; Yvonne Ng; Shi-Xiong Tan; Michael J Buckley; David E James
Novel systems for dynamically assessing insulin action in live cells reveals heterogeneity in the insulin response.
Traffic (Copenhagen, Denmark) 2013;14(3):259-73.
2013: Tristan J Iseli; David E James; Edward W Kraegen; Nigel Turner; Sheng Yao; Yang Ye; Zeng C; Gregory J Cooney; Ji-Ming Ye
Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKβ.
PloS one 2013;8(4):e62309.
2012: Shi-Xiong Tan; James G Burchfield; David G Lambright; Yvonne Ng; Georg Ramm; Jacqueline Stöckli; David E James
The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes.
Molecular and cellular biology 2012;32(24):4946-59.
2012: Gordon J King; Wilko G A Duprez; Shu-Hong Hu; David E James; Russell J Jarrott; Jagath R Junutula; Christopher C Meoli; Jacqueline Stöckli; Andrew E Whitten; Brit Winnen; Jennifer L Martin
Membrane curvature protein exhibits interdomain flexibility and binds a small GTPase.
The Journal of biological chemistry 2012;287(49):40996-1006.
2012: Jonathan R Davey; Sean J Humphrey; David E James; Jagath R Junutula; David G Lambright; Ashwini K Mishra; Jacqueline Stöckli
TBC1D13 is a RAB35 specific GAP that plays an important role in GLUT4 trafficking in adipocytes.
Traffic (Copenhagen, Denmark) 2012;13(10):1429-41.
2012: Michelle P Christie; Brett M Collins; Anthony P Duff; Shu-Hong Hu; David E James; Russell J Jarrott; Gordon J King; Philip Callow; Kai-En Chen; Andrew E Whitten; Jennifer L Martin
Low-resolution solution structures of Munc18:Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(25):9816-21.
2012: Sean J Humphrey; David E James
Uncaging akt.
Science signaling 2012;5(223):pe20.
2012: Kyle L Hoehn; George J Cooney; Nigel Turner; David E James
Phenotypic discrepancies in acetyl-CoA carboxylase 2-deficient mice.
The Journal of biological chemistry 2012;287(19):15801; author reply 15802.
2012: Shi-Xiong Tan; Shireen Vali; Daniel J Fazakerley; David E James; Jagath R Junutula; Poh-Sim Khoo; Ansu Kumar; Christopher C Meoli; Yvonne Ng; Jacqueline Stöckli
Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes.
The Journal of biological chemistry 2012;287(9):6128-38.
2012: Shu-Hong Hu; David E James; Alun Jones; Gordon J King; Alexander F Rowland; Andrew E Whitten; Jennifer L Martin
The weak complex between RhoGAP protein ARHGAP22 and signal regulatory protein 14-3-3 has 1:2 stoichiometry and a single peptide binding mode.
PloS one 2012;7(8):e41731.
2011: Jacqueline Stöckli; Daniel J Fazakerley; David E James
GLUT4 exocytosis.
Journal of cell science 2011;124(Pt 24):4147-59.
2011: Alexander F Rowland; Mark Larance; William E Hughes; David E James
Identification of RhoGAP22 as an Akt-dependent regulator of cell motility in response to insulin.
Molecular and cellular biology 2011;31(23):4789-800.
2011: Markus Bach; David E James; Mark Larance; Georg Ramm
The serine/threonine kinase ULK1 is a target of multiple phosphorylation events.
The Biochemical journal 2011;440(2):283-91.
2011: Matthew J Prior; Jamie Soul; Michael Buckley; James Burchfield; Jonathon R Davey; Michael Guilhaus; Sean Humphrey; Hiroshi Kanazawa; Carol Kistler; Penelope J La-Borde; Mark Larance; Robert T Lawrence; Robert G Parton; David E James
Quantitative proteomic analysis of the adipocyte plasma membrane.
Journal of proteome research 2011;10(11):4970-82.
2011: Alexander F Rowland; Daniel J Fazakerley; David E James
Mapping insulin/GLUT4 circuitry.
Traffic (Copenhagen, Denmark) 2011;12(6):672-81.
2010: Mark Larance; Alexander F Rowland; Kyle L Hoehn; David T Humphreys; Thomas Preiss; Michael Guilhaus; David E James
Global phosphoproteomics identifies a major role for AKT and 14-3-3 in regulating EDC3.
Molecular & cellular proteomics : MCP 2010;9(4):682-94.
2010: Kyle L Hoehn; Nigel Turner; Michael M Swarbrick; Donna Wilks; Elaine Preston; Yuwei Phua; Himani Joshi; Stuart M Furler; Mark Larance; Bronwyn D Hegarty; Simon J Leslie; Russell Pickford; Andrew J Hoy; Edward W Kraegen; David E James; Gregory J Cooney
Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity.
Cell metabolism 2010;11(1):70-6.
2009: Kyle Hoehn; Adam B Salmon; Cordula Hohnen-Behrens; Nigel Turner; Andrew J Hoy; Ghassan J Maghzal; Roland Stocker; Holly Van Remmen; Edward W Kraegen; Greg J Cooney; Arlan G Richardson; David E James
Insulin resistance is a cellular antioxidant defense mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(42):17787-92.
2009: Jacqueline Stöckli; David E James
Insulin action under arrestin.
Cell metabolism 2009;9(3):213-4.
2008: Jacqueline Stöckli; Jonathan R Davey; Cordula Hohnen-Behrens; Aimin Xu; David E James; Georg Ramm
Regulation of glucose transporter 4 translocation by the Rab guanosine triphosphatase-activating protein AS160/TBC1D4: role of phosphorylation and membrane association.
Molecular endocrinology (Baltimore, Md.) 2008;22(12):2703-15.
2008: Ming Fai Yip; Georg Ramm; Mark Larance; Kyle Hoehn; Mark C Wagner; Michael Guilhaus; David E James
CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes.
Cell metabolism 2008;8(5):384-98.
2008: Tilman Brummer; Mark Larance; Maria Teresa Herrera Abreu; Ruth J Lyons; Paul Timpson; Christoph H Emmerich; Emmy D G Fleuren; Gillian M Lehrbach; Daniel Schramek; Michael Guilhaus; David E James; Roger J Daly
Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.
The EMBO journal 2008;27(17):2305-16.
2008: Jamie A Lopez; Edwin P Kwan; Li Xie; Yu He; David E James; Herbert Y Gaisano
The RalA GTPase is a central regulator of insulin exocytosis from pancreatic islet beta cells.
The Journal of biological chemistry 2008;283(26):17939-45.
2008: Kyle Hoehn; Cordula Hohnen-Behrens; Anna Cederberg; Lindsay Wu; Nigel Turner; Tomoyuki Yuasa; Yousuke Ebina; David E James
IRS1-independent defects define major nodes of insulin resistance.
Cell metabolism 2008;7(5):421-33.
2008: Nigel Turner; Jing-Ya Li; Alison Gosby; Sabrina W C To; Zhe Cheng; Hiroyuki Miyoshi; Makoto M Taketo; Gregory J Cooney; Edward W Kraegen; David E James; Li-Hong Hu; Jia Li; Ji-Ming Ye
Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action.
Diabetes 2008;57(5):1414-8.
2008: Yvonne Ng; Georg Ramm; Jamie A Lopez; David E James
Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes.
Cell metabolism 2008;7(4):348-56.
2008: Mark Larance; Georg Ramm; David E James
The GLUT4 code.
Molecular endocrinology (Baltimore, Md.) 2008;22(2):226-33.
2008: Roland Govers; David E James; Adelle Coster
High-throughput analysis of the dynamics of recycling cell surface proteins.
Methods in molecular biology (Clifton, N.J.) 2008;440():129-46.
2007: Andrew J Hoy; Clinton R Bruce; Anna Cederberg; Nigel Turner; David E James; Gregory J Cooney; Edward W Kraegen
Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation.
American journal of physiology. Endocrinology and metabolism 2007;293(5):E1358-64.
2007: Catherine F Latham; Shu-Hong Hu; Christine L Gee; Christopher J Armishaw; Paul F Alewood; David E James; Jennifer L Martin
Crystallization and preliminary X-ray diffraction of the Munc18c-syntaxin4 (1-29) complex.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 6):524-8.
2007: Shu-Hong Hu; Catherine F Latham; Christine L Gee; David E James; Jennifer L Martin
Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(21):8773-8.
2007: Mark E Cleasby; Tracie A Reinten; Gregory J Cooney; David E James; Edward W Kraegen
Functional studies of Akt isoform specificity in skeletal muscle in vivo; maintained insulin sensitivity despite reduced insulin receptor substrate-1 expression.
Molecular endocrinology (Baltimore, Md.) 2007;21(1):215-28.
2006: Juan Carlos Molero; Nigel Turner; Christine B F Thien; Wallace Y Langdon; David E James; Gregory J Cooney
Genetic ablation of the c-Cbl ubiquitin ligase domain results in increased energy expenditure and improved insulin action.
Diabetes 2006;55(12):3411-7.
2006: Andrew L Carey; Gregory R Steinberg; S Lance Macaulay; Walter G Thomas; Anna G Holmes; Georg Ramm; Oja Prelovsek; Cordula Hohnen-Behrens; Matthew J Watt; David E James; Bruce E Kemp; Bente Klarlund Pedersen; Mark A Febbraio
Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase.
Diabetes 2006;55(10):2688-97.
2006: Catherine F Latham; Jamie A Lopez; Shu-Hong Hu; Christine L Gee; Elizabeth Westbury; Duncan H Blair; Christopher J Armishaw; Paul F Alewood; Nia J Bryant; David E James; Jennifer L Martin
Molecular dissection of the Munc18c/syntaxin4 interaction: implications for regulation of membrane trafficking.
Traffic (Copenhagen, Denmark) 2006;7(10):1408-19.
2006: Georg Ramm; Mark Larance; Michael Guilhaus; David E James
A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160.
The Journal of biological chemistry 2006;281(39):29174-80.
2006: Juan Carlos Molero; Samuel G Waring; Adrian Cooper; Nigel Turner; Ross Laybutt; Gregory J Cooney; David E James
Casitas b-lineage lymphoma-deficient mice are protected against high-fat diet-induced obesity and insulin resistance.
Diabetes 2006;55(3):708-15.
2006: Elaine C Thomas; Yang Zhe; Juan Carlos Molero; Carsten Schmitz-Peiffer; Georg Ramm; David E James; Jonathan P Whitehead
The subcellular fractionation properties and function of insulin receptor substrate-1 (IRS-1) are independent of cytoskeletal integrity.
The international journal of biochemistry & cell biology 2006;38(10):1686-99.
2005: Mark Larance; Georg Ramm; Jacqueline Stöckli; Ellen M van Dam; Stephanie Winata; Valerie Wasinger; Fiona Simpson; Michael Graham; Jagath R Junutula; Michael Guilhaus; David E James
Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking.
The Journal of biological chemistry 2005;280(45):37803-13.
2005: Mark E Cleasby; Jonathan R Davey; Tracie A Reinten; Michael W Graham; David E James; Edward W Kraegen; Gregory J Cooney
Acute bidirectional manipulation of muscle glucose uptake by in vivo electrotransfer of constructs targeting glucose transporter genes.
Diabetes 2005;54(9):2702-11.
2005: Fiona Simpson; Sally Martin; Timothy M Evans; Markus Kerr; David E James; Robert Parton; Rohan Teasdale; Carol Wicking
A novel hook-related protein family and the characterization of hook-related protein 1.
Traffic (Copenhagen, Denmark) 2005;6(6):442-58.
2005: Ellen M van Dam; Roland Govers; David E James
Akt activation is required at a late stage of insulin-induced GLUT4 translocation to the plasma membrane.
Molecular endocrinology (Baltimore, Md.) 2005;19(4):1067-77.
2005: Robert R Rice; Andrew N Muirhead; Bruce T Harrison; Andrew J Kassianos; Petra L Sedlak; Narelle J Maugeri; Peter J Goss; Jonathan R Davey; David E James; Michael W Graham
Simple, robust strategies for generating DNA-directed RNA interference constructs.
Methods in enzymology 2005;392():405-19.
2004: Juan Carlos Molero; Thomas E Jensen; Phil C Withers; Michelle Couzens; Herbert Herzog; Christine B F Thien; Wallace Y Langdon; Ken Walder; Maria A Murphy; David D L Bowtell; David E James; Gregory J Cooney
c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action.
The Journal of clinical investigation 2004;114(9):1326-33.
2004: Adelle Coster; Roland Govers; David E James
Insulin stimulates the entry of GLUT4 into the endosomal recycling pathway by a quantal mechanism.
Traffic (Copenhagen, Denmark) 2004;5(10):763-71.
2004: Jonathan P Whitehead; Fiona Simpson; Michelle M Hill; Elaine C Thomas; Lisa M Connolly; Frank Collart; Richard J Simpson; David E James
Insulin and oleate promote translocation of inosine-5' monophosphate dehydrogenase to lipid bodies.
Traffic (Copenhagen, Denmark) 2004;5(10):739-49.
2004: Roland Govers; Adelle Coster; David E James
Insulin increases cell surface GLUT4 levels by dose dependently discharging GLUT4 into a cell surface recycling pathway.
Molecular and cellular biology 2004;24(14):6456-66.
2004: Gregory J Cooney; Ruth J Lyons; A Jayne Crew; Thomas E Jensen; Juan Carlos Molero; Christopher J Mitchell; Trevor J Biden; Christopher J Ormandy; David E James; Roger J Daly
Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.
The EMBO journal 2004;23(3):582-93.
2004: Kouichi Inukai; Annette M Shewan; Wendy S Pascoe; Shigehiro Katayama; David E James; Yoshitomo Oka
Carboxy terminus of glucose transporter 3 contains an apical membrane targeting domain.
Molecular endocrinology (Baltimore, Md.) 2004;18(2):339-49.
2003: Shu-Hong Hu; Christine L Gee; Catherine F Latham; Scott W Rowlinson; Ulrika Rova; Alun Jones; Judy A Halliday; Nia J Bryant; David E James; Jennifer L Martin
Recombinant expression of Munc18c in a baculovirus system and interaction with syntaxin4.
Protein expression and purification 2003;31(2):305-10.
2003: Charlotte Widberg; Nia J Bryant; Milena Girotti; Shane Rea; David E James
Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation.
The Journal of biological chemistry 2003;278(37):35093-101.
2003: Nia J Bryant; David E James
The Sec1p/Munc18 (SM) protein, Vps45p, cycles on and off membranes during vesicle transport.
The Journal of cell biology 2003;161(4):691-6.
2003: Annette M Shewan; Ellen M van Dam; Sally Martin; Tang Bor Luen; Wanjin Hong; Nia J Bryant; David E James
GLUT4 recycles via a trans-Golgi network (TGN) subdomain enriched in Syntaxins 6 and 16 but not TGN38: involvement of an acidic targeting motif.
Molecular biology of the cell 2003;14(3):973-86.
2003: Julia K Pagan; Fiona G Wylie; Shannon Joseph; Charlotte Widberg; Nia J Bryant; David E James; Jennifer L Stow
The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion.
Current biology : CB 2003;13(2):156-60.
2002: Isabel C Morrow; Shane Rea; Sally Martin; Ian Prior; Rainer Prohaska; John F Hancock; David E James; Robert Parton
Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation.
The Journal of biological chemistry 2002;277(50):48834-41.
2002: Robert Parton; Juan Carlos Molero; Matthias Floetenmeyer; Kathryn M Green; David E James
Characterization of a distinct plasma membrane macrodomain in differentiated adipocytes.
The Journal of biological chemistry 2002;277(48):46769-78.
2002: Nia J Bryant; Roland Govers; David E James
Regulated transport of the glucose transporter GLUT4.
Nature reviews. Molecular cell biology 2002;3(4):267-77.
2001: Juan Carlos Molero; Jonathan P Whitehead; T Meerloo; David E James
Nocodazole inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes via a microtubule-independent mechanism.
The Journal of biological chemistry 2001;276(47):43829-35.
2001: Jonathan P Whitehead; Juan Carlos Molero; S Clark; Sally Martin; G Meneilly; David E James
The role of Ca2+ in insulin-stimulated glucose transport in 3T3-L1 cells.
The Journal of biological chemistry 2001;276(30):27816-24.
2001: Nia J Bryant; David E James
Vps45p stabilizes the syntaxin homologue Tlg2p and positively regulates SNARE complex formation.
The EMBO journal 2001;20(13):3380-8.
2001: N Wade; Nia J Bryant; Lisa M Connolly; R J Simpson; J Paul Luzio; Robert C Piper; David E James
Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells.
The Journal of biological chemistry 2001;276(23):19820-7.
2001: Fiona Simpson; Jonathan P Whitehead; David E James
GLUT4--at the cross roads between membrane trafficking and signal transduction.
Traffic (Copenhagen, Denmark) 2001;2(1):2-11.
2000: Georg Ramm; Jan W Slot; David E James; Willem Stoorvogel
Insulin recruits GLUT4 from specialized VAMP2-carrying vesicles as well as from the dynamic endosomal/trans-Golgi network in rat adipocytes.
Molecular biology of the cell 2000;11(12):4079-91.
2000: Sally Martin; CA Millar; C T Lyttle; T Meerloo; BJ Marsh; Gwyn W Gould; David E James
Effects of insulin on intracellular GLUT4 vesicles in adipocytes: evidence for a secretory mode of regulation.
Journal of cell science 2000;113 Pt 19():3427-38.
2000: Annette M Shewan; BJ Marsh; DR Melvin; Sally Martin; Gwyn W Gould; David E James
The cytosolic C-terminus of the glucose transporter GLUT4 contains an acidic cluster endosomal targeting motif distal to the dileucine signal.
The Biochemical journal 2000;350 Pt 1():99-107.
2000: Michelle M Hill; Lisa M Connolly; R J Simpson; David E James
Differential protein phosphorylation in 3T3-L1 adipocytes in response to insulin versus platelet-derived growth factor. No evidence for a phosphatidylinositide 3-kinase-independent pathway in insulin signaling.
The Journal of biological chemistry 2000;275(32):24313-20.
2000: Sally Martin; Georg Ramm; C T Lyttle; T Meerloo; Willem Stoorvogel; David E James
Biogenesis of insulin-responsive GLUT4 vesicles is independent of brefeldin A-sensitive trafficking.
Traffic (Copenhagen, Denmark) 2000;1(8):652-60.
2000: Jonathan P Whitehead; SF Clark; B Urso; David E James
Signalling through the insulin receptor.
Current opinion in cell biology 2000;12(2):222-8.
2000: SF Clark; Juan Carlos Molero; David E James
Release of insulin receptor substrate proteins from an intracellular complex coincides with the development of insulin resistance.
The Journal of biological chemistry 2000;275(6):3819-26.
2000: CA Millar; T Meerloo; Sally Martin; Gilles R X Hickson; N J Shimwell; Michael J O Wakelam; David E James; Gwyn W Gould
Adipsin and the glucose transporter GLUT4 traffic to the cell surface via independent pathways in adipocytes.
Traffic (Copenhagen, Denmark) 2000;1(2):141-51.
2000: M Hashiramoto; David E James
Characterization of insulin-responsive GLUT4 storage vesicles isolated from 3T3-L1 adipocytes.
Molecular and cellular biology 2000;20(1):416-27.
1999: CA Millar; Annette M Shewan; Gilles R X Hickson; David E James; Gwyn W Gould
Differential regulation of secretory compartments containing the insulin-responsive glucose transporter 4 in 3T3-L1 adipocytes.
Molecular biology of the cell 1999;10(11):3675-88.
1999: Michelle M Hill; SF Clark; David Tucker; M J Birnbaum; David E James; S Lance Macaulay
A role for protein kinase Bbeta/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes.
Molecular and cellular biology 1999;19(11):7771-81.
1999: DR Melvin; BJ Marsh; Adrian R Walmsley; David E James; Gwyn W Gould
Analysis of amino and carboxy terminal GLUT-4 targeting motifs in 3T3-L1 adipocytes using an endosomal ablation technique.
Biochemistry 1999;38(5):1456-62.
1999: Sally Martin; JW Slot; David E James
GLUT4 trafficking in insulin-sensitive cells. A morphological review.
Cell biochemistry and biophysics 1999;30(1):89-113.
1998: BJ Marsh; Sally Martin; DR Melvin; L B Martin; R A Alm; Gwyn W Gould; David E James
Mutational analysis of the carboxy-terminal phosphorylation site of GLUT-4 in 3T3-L1 adipocytes.
The American journal of physiology 1998;275(3 Pt 1):E412-22.
1998: Shane Rea; L B Martin; S McIntosh; S Lance Macaulay; T Ramsdale; G Baldini; David E James
Syndet, an adipocyte target SNARE involved in the insulin-induced translocation of GLUT4 to the cell surface.
The Journal of biological chemistry 1998;273(30):18784-92.
1998: SF Clark; Sally Martin; Amanda J Carozzi; Michelle M Hill; David E James
Intracellular localization of phosphatidylinositide 3-kinase and insulin receptor substrate-1 in adipocytes: potential involvement of a membrane skeleton.
The Journal of cell biology 1998;140(5):1211-25.
1998: L B Martin; Annette M Shewan; CA Millar; Gwyn W Gould; David E James
Vesicle-associated membrane protein 2 plays a specific role in the insulin-dependent trafficking of the facilitative glucose transporter GLUT4 in 3T3-L1 adipocytes.
The Journal of biological chemistry 1998;273(3):1444-52.
1998: M Hashiramoto; David E James
Snareing GLUT4 at the plasma membrane in muscle and fat.
Advances in experimental medicine and biology 1998;441():47-61.
1998: T J Anderson; Sally Martin; J L Berka; David E James; JW Slot; Jennifer L Stow
Distinct localization of renin and GLUT-4 in juxtaglomerular cells of mouse kidney.
The American journal of physiology 1998;274(1 Pt 2):F26-33.
1997: Michelle M Hill; SF Clark; David E James
Insulin-regulatable phosphoproteins in 3T3-L1 adipocytes form detergent-insoluble complexes not associated with caveolin.
Electrophoresis 1997;18(14):2629-37.
1997: Shane Rea; David E James
Moving GLUT4: the biogenesis and trafficking of GLUT4 storage vesicles.
Diabetes 1997;46(11):1667-77.
1997: Sally Martin; J E Rice; Gwyn W Gould; Susanna R Keller; JW Slot; David E James
The glucose transporter GLUT4 and the aminopeptidase vp165 colocalise in tubulo-vesicular elements in adipocytes and cardiomyocytes.
Journal of cell science 1997;110 ( Pt 18)():2281-91.
1997: S Lance Macaulay; Shane Rea; Keith H Gough; Colin W Ward; David E James
Botulinum E toxin light chain does not cleave SNAP-23 and only partially impairs insulin stimulation of GLUT4 translocation in 3T3-L1 cells.
Biochemical and biophysical research communications 1997;237(2):388-93.
1997: CA Millar; David E James; Gwyn W Gould
Characterisation of proteins associated with the GLUT4 intracellular compartment.
Biochemical Society transactions 1997;25(3):465S.
1997: Harry F G Heijnen; Viola Oorschot; Jan J Sixma; Jan W Slot; David E James
Thrombin stimulates glucose transport in human platelets via the translocation of the glucose transporter GLUT-3 from alpha-granules to the cell surface.
The Journal of cell biology 1997;138(2):323-30.
1997: Jan W Slot; G Garruti; S Martin; Viola Oorschot; George Posthuma; Edward Kraegen; R Laybutt; G Thibault; David E James
Glucose transporter (GLUT-4) is targeted to secretory granules in rat atrial cardiomyocytes.
The Journal of cell biology 1997;137(6):1243-54.
1997: Marie Pantaleon; Mark B Harvey; Wendy S Pascoe; David E James; Peter L Kaye
Glucose transporter GLUT3: ontogeny, targeting, and role in the mouse blastocyst.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3795-800.
1997: Ross Tellam; David E James; Tom H Stevens; Robert C Piper
Identification of a mammalian Golgi Sec1p-like protein, mVps45.
The Journal of biological chemistry 1997;272(10):6187-93.
1997: Ross Tellam; S Lance Macaulay; S McIntosh; DR Hewish; Colin W Ward; David E James
Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4.
The Journal of biological chemistry 1997;272(10):6179-86.
1997: M N Jagadish; Ross Tellam; S Lance Macaulay; Keith H Gough; David E James; Colin W Ward
Novel isoform of syntaxin 1 is expressed in mammalian cells.
The Biochemical journal 1997;321 ( Pt 1)():151-6.
1996: W S Pascoe; K Inukai; Y Oka; JW Slot; David E James
Differential targeting of facilitative glucose transporters in polarized epithelial cells.
The American journal of physiology 1996;271(2 Pt 1):C547-54.
1996: Sally Martin; Ross Tellam; C Livingstone; JW Slot; G W Gould; David E James
The glucose transporter (GLUT-4) and vesicle-associated membrane protein-2 (VAMP-2) are segregated from recycling endosomes in insulin-sensitive cells.
The Journal of cell biology 1996;134(3):625-35.
1996: C Livingstone; David E James; J E Rice; D Hanpeter; G W Gould
Compartment ablation analysis of the insulin-responsive glucose transporter (GLUT4) in 3T3-L1 adipocytes.
The Biochemical journal 1996;315 ( Pt 2)():487-95.
1995: BJ Marsh; R A Alm; S R McIntosh; David E James
Molecular regulation of GLUT-4 targeting in 3T3-L1 adipocytes.
The Journal of cell biology 1995;130(5):1081-91.
1995: D Hanpeter; David E James
Characterization of the intracellular GLUT-4 compartment.
Molecular membrane biology 1995;12(3):263-9.
1995: Ko Kotani; A J Carozzi; Hiroshi Sakaue; Kenta Hara; L J Robinson; SF Clark; Kazuyoshi Yonezawa; David E James; Masato Kasuga
Requirement for phosphoinositide 3-kinase in insulin-stimulated GLUT4 translocation in 3T3-L1 adipocytes.
Biochemical and biophysical research communications 1995;209(1):343-8.
1995: Ross Tellam; S McIntosh; David E James
Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues.
The Journal of biological chemistry 1995;270(11):5857-63.
1994: David E James; R C Piper
Insulin resistance, diabetes, and the insulin-regulated trafficking of GLUT-4.
The Journal of cell biology 1994;126(5):1123-6.
1994: David E James
Targeting of the insulin-regulatable glucose transporter (GLUT-4).
Biochemical Society transactions 1994;22(3):668-70.
1993: L J Robinson; Z F Razzack; J C Lawrence; David E James
Mitogen-activated protein kinase activation is not sufficient for stimulation of glucose transport or glycogen synthase in 3T3-L1 adipocytes.
The Journal of biological chemistry 1993;268(35):26422-7.
1993: R C Piper; David E James; J W Slot; C Puri; J C Lawrence
GLUT4 phosphorylation and inhibition of glucose transport by dibutyryl cAMP.
The Journal of biological chemistry 1993;268(22):16557-63.
1993: R C Piper; C Tai; P Kulesza; S Pang; D Warnock; J Baenziger; J W Slot; H J Geuze; C Puri; David E James
GLUT-4 NH2 terminus contains a phenylalanine-based targeting motif that regulates intracellular sequestration.
The Journal of cell biology 1993;121(6):1221-32.
1993: David E James; R C Piper; J W Slot
Targeting of mammalian glucose transporters.
Journal of cell science 1993;104 ( Pt 3)():607-12.
1992: K J Rodnick; R C Piper; J W Slot; David E James
Interaction of insulin and exercise on glucose transport in muscle.
Diabetes care 1992;15(11):1679-89.
1992: D S Harris; J W Slot; H J Geuze; David E James
Polarized distribution of glucose transporter isoforms in Caco-2 cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7556-60.
1992: L J Robinson; David E James
Insulin-regulated sorting of glucose transporters in 3T3-L1 adipocytes.
The American journal of physiology 1992;263(2 Pt 1):E383-93.
1992: D R Studelska; C Campbell; S Pang; K J Rodnick; David E James
Developmental expression of insulin-regulatable glucose transporter GLUT-4.
The American journal of physiology 1992;263(1 Pt 1):E102-6.
1992: L J Robinson; S Pang; D S Harris; J Heuser; David E James
Translocation of the glucose transporter (GLUT4) to the cell surface in permeabilized 3T3-L1 adipocytes: effects of ATP insulin, and GTP gamma S and localization of GLUT4 to clathrin lattices.
The Journal of cell biology 1992;117(6):1181-96.
1992: R C Piper; C Tai; J W Slot; C S Hahn; C M Rice; H Huang; David E James
The efficient intracellular sequestration of the insulin-regulatable glucose transporter (GLUT-4) is conferred by the NH2 terminus.
The Journal of cell biology 1992;117(4):729-43.
1992: K J Rodnick; J W Slot; D R Studelska; D E Hanpeter; L J Robinson; H J Geuze; David E James
Immunocytochemical and biochemical studies of GLUT4 in rat skeletal muscle.
The Journal of biological chemistry 1992;267(9):6278-85.
1992: K J Rodnick; E J Henriksen; David E James; John O Holloszy
Exercise training, glucose transporters, and glucose transport in rat skeletal muscles.
The American journal of physiology 1992;262(1 Pt 1):C9-14.
1991: Jan W Slot; Hans J Geuze; S Gigengack; David E James; G E Lienhard
Translocation of the glucose transporter GLUT4 in cardiac myocytes of the rat.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(17):7815-9.
1991: P M Haney; J W Slot; R C Piper; David E James; Mike Mueckler
Intracellular targeting of the insulin-regulatable glucose transporter (GLUT4) is isoform specific and independent of cell type.
The Journal of cell biology 1991;114(4):689-99.
1991: E J Henriksen; K J Rodnick; C E Mondon; David E James; John O Holloszy
Effect of denervation or unweighting on GLUT-4 protein in rat soleus muscle.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;70(5):2322-7.
1991: Jan W Slot; Hans J Geuze; S Gigengack; G E Lienhard; David E James
Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat.
The Journal of cell biology 1991;113(1):123-35.
1991: R C Piper; L J Hess; David E James
Differential sorting of two glucose transporters expressed in insulin-sensitive cells.
The American journal of physiology 1991;260(3 Pt 1):C570-80.
1990: J C Lawrence; J F Hiken; David E James
Stimulation of glucose transport and glucose transporter phosphorylation by okadaic acid in rat adipocytes.
The Journal of biological chemistry 1990;265(32):19768-76.
1990: K J Rodnick; John O Holloszy; C E Mondon; David E James
Effects of exercise training on insulin-regulatable glucose-transporter protein levels in rat skeletal muscle.
Diabetes 1990;39(11):1425-9.
1990: Jan W Slot; R Moxley; Hans J Geuze; David E James
No evidence for expression of the insulin-regulatable glucose transporter in endothelial cells.
Nature 1990;346(6282):369-71.
1990: J C Lawrence; J F Hiken; David E James
Phosphorylation of the glucose transporter in rat adipocytes. Identification of the intracellular domain at the carboxyl terminus as a target for phosphorylation in intact-cells and in vitro.
The Journal of biological chemistry 1990;265(4):2324-32.
1989: David E James; J Hiken; J C Lawrence
Isoproterenol stimulates phosphorylation of the insulin-regulatable glucose transporter in rat adipocytes.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8368-72.