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Sanford Markey

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Michael Brad Strader; Nina Costantino; Christopher A Elkins; Cai Yun Chen; Isha Patel; Anthony J Makusky; John S Choy; Donald L Court; Sanford Markey; Jeffrey A Kowalak
A proteomic and transcriptomic approach reveals new insight into beta-methylthiolation of Escherichia coli ribosomal protein S12.
Jeffrey N Savas; Anthony Makusky; Søren Ottosen; David BAILLAT; Florian Then; Dimitri Krainc; Ramin Shiekhattar; Sanford Markey; Naoko Tanese
Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies.
Timothy P Lockwich; Jaya Pant; Anthony Makusky; Ewa Jankowska-Stephens; Jeffrey A Kowalak; Sanford Markey; Indu S Ambudkar
Analysis of TRPC3-interacting proteins by tandem mass spectrometry.

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2011: Michael Brad Strader; Nina Costantino; Christopher A Elkins; Cai Yun Chen; Isha Patel; Anthony J Makusky; John S Choy; Donald L Court; Sanford Markey; Jeffrey A Kowalak
A proteomic and transcriptomic approach reveals new insight into beta-methylthiolation of Escherichia coli ribosomal protein S12.
Molecular & cellular proteomics : MCP 2011;10(3):M110.005199.
2008: Jeffrey N Savas; Anthony Makusky; Søren Ottosen; David BAILLAT; Florian Then; Dimitri Krainc; Ramin Shiekhattar; Sanford Markey; Naoko Tanese
Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):10820-5.
2008: Timothy P Lockwich; Jaya Pant; Anthony Makusky; Ewa Jankowska-Stephens; Jeffrey A Kowalak; Sanford Markey; Indu S Ambudkar
Analysis of TRPC3-interacting proteins by tandem mass spectrometry.
Journal of proteome research 2008;7(3):979-89.
2008: Dhaval Nanavati; Marjan Gucek; Jacqueline L S Milne; Sriram Subramaniam; Sanford Markey
Stoichiometry and absolute quantification of proteins with mass spectrometry using fluorescent and isotope-labeled concatenated peptide standards.
Molecular & cellular proteomics : MCP 2008;7(2):442-7.
2007: Ayse Dosemeci; Anthony J Makusky; Ewa Jankowska-Stephens; Xiaoyu Yang; Douglas J Slotta; Sanford Markey
Composition of the synaptic PSD-95 complex.
Molecular & cellular proteomics : MCP 2007;6(10):1749-60.
2007: Peter B Harrington; Claudine Laurent; Douglas F Levinson; Pat Levitt; Sanford Markey
Bootstrap classification and point-based feature selection from age-staged mouse cerebellum tissues of matrix assisted laser desorption/ionization mass spectra using a fuzzy rule-building expert system.
Analytica chimica acta 2007;599(2):219-31.
2006: Hidetsugu Fujigaki; Kuniaki Saito; Felix Lin; Suwako Fujigaki; Kanako Takahashi; Brian M Martin; Cai Y Chen; Junichi Masuda; Jeffrey Kowalak; Osamu Takikawa; Mitsuru Seishima; Sanford Markey
Nitration and inactivation of IDO by peroxynitrite.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):372-9.
2005: Claudine Laurent; Douglas F Levinson; Sarah A Schwartz; Peter B Harrington; Sanford Markey; Richard M Caprioli; Pat Levitt
Direct profiling of the cerebellum by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: A methodological study in postnatal and adult mouse.
Journal of neuroscience research 2005;81(5):613-21.
2005: Ming Xu; Lewis Y Geer; Stephen H Bryant; Jeri S Roth; Jeffrey A Kowalak; Dawn M Maynard; Sanford Markey
Assessing data quality of peptide mass spectra obtained by quadrupole ion trap mass spectrometry.
Journal of proteome research 2005;4(2):300-5.
2005: Junichi Masuda; Dawn M Maynard; Masayuki Nishimura; Teruhisa Ueda; Jeffrey A Kowalak; Sanford Markey
Fully automated micro- and nanoscale one- or two-dimensional high-performance liquid chromatography system for liquid chromatography-mass spectrometry compatible with non-volatile salts for ion exchange chromatography.
Journal of chromatography. A 2005;1063(1-2):57-69.
2004: Dawn M Maynard; Junichi Masuda; Xiaoyu Yang; Jeffrey A Kowalak; Sanford Markey
Characterizing complex peptide mixtures using a multi-dimensional liquid chromatography-mass spectrometry system: Saccharomyces cerevisiae as a model system.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;810(1):69-76.
2004: Xiaoyu Yang; Vijay Dondeti; Rebecca Dezube; Dawn M Maynard; Lewis Y Geer; Jonathan Epstein; Xiongfong Chen; Sanford Markey; Jeffrey A Kowalak
DBParser: web-based software for shotgun proteomic data analyses.
Journal of proteome research 2004;3(5):1002-8.
2004: Lewis Y Geer; Sanford Markey; Jeffrey A Kowalak; Lukas Wagner; Ming Xu; Dawn M Maynard; Xiaoyu Yang; Wenyao Shi; Stephen H Bryant
Open mass spectrometry search algorithm.
Journal of proteome research 2004;3(5):958-64.
2002: Jason Evans; Tao Chin Wang; Melvyn P Heyes; Sanford Markey
LC/MS analysis of NAD biosynthesis using stable isotope pyridine precursors.
Analytical biochemistry 2002;306(2):197-203.
2002: Tomoyuki Kita; Paul F Morrison; Melvyn P Heyes; Sanford Markey
Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the L-kynurenine and quinolinic acid pools in brain.
Journal of neurochemistry 2002;82(2):258-68.
2001: X Jian; WA Clark; Jeffrey A Kowalak; Sanford Markey; W F Simonds; John K Northup
Gbetagamma affinity for bovine rhodopsin is determined by the carboxyl-terminal sequences of the gamma subunit.
The Journal of biological chemistry 2001;276(51):48518-25.
2001: Zhi-Gang Jiang; C Piggee; Melvyn P Heyes; C Murphy; B Quearry; M Bauer; Jialin Charles Zheng; Howard Gendelman; Sanford Markey
Glutamate is a mediator of neurotoxicity in secretions of activated HIV-1-infected macrophages.
Journal of neuroimmunology 2001;117(1-2):97-107.
2000: Sanford Markey; T Dudding; T C Wang
Base- and acid-catalyzed interconversions of O-acyl- and N-acyl-ethanolamines: a cautionary note for lipid analyses.
Journal of lipid research 2000;41(4):657-62.
1999: H Y Yang; F Karoum; Christian Felder; H Badger; T C Wang; Sanford Markey
GC/MS analysis of anandamide and quantification of N-arachidonoylphosphatidylethanolamides in various brain regions, spinal cord, testis, and spleen of the rat.
Journal of neurochemistry 1999;72(5):1959-68.
1999: T Kita; Melvyn P Heyes; Paul F Morrison; Sanford Markey
Labeled kynurenine pharmacokinetic modeling studies in gerbils. Nonequilibrium between infused and endogenous kynurenine.
Advances in experimental medicine and biology 1999;467():315-20.
1998: Melvyn P Heyes; K Saito; Andrew Lackner; C A Wiley; Cristian L Achim; Sanford Markey
Sources of the neurotoxin quinolinic acid in the brain of HIV-1-infected patients and retrovirus-infected macaques.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(10):881-96.
1998: Elio Lugaresi; Pasquale Montagna; Paolo Tinuper; Giuseppe Plazzi; Roberto Gallassi; T C Wang; Sanford Markey; Jeffrey rothstein
Endozepine stupor. Recurring stupor linked to endozepine-4 accumulation.
Brain : a journal of neurology 1998;121 ( Pt 1)():127-33.
1997: Melvyn P Heyes; K Saito; C Y Chen; Margit G Proescholdt; T S Nowak; J Li; KE Beagles; M A Proescholdt; Mark Zito; K Kawai; Sanford Markey
Species heterogeneity between gerbils and rats: quinolinate production by microglia and astrocytes and accumulations in response to ischemic brain injury and systemic immune activation.
Journal of neurochemistry 1997;69(4):1519-29.
1997: Yoshitatsu Sei; K Nishida; Y Kustova; Sanford Markey; Herbert C Morse; Anthony Basile
Pentoxifylline decreases brain levels of platelet activating factor in murine AIDS.
European journal of pharmacology 1997;325(1):81-4.
1996: Melvyn P Heyes; C L Achim; C A Wiley; E O Major; K Saito; Sanford Markey
Human microglia convert l-tryptophan into the neurotoxin quinolinic acid.
The Biochemical journal 1996;320 ( Pt 2)():595-7.
1996: D B Naritsin; Sanford Markey
Assessment of DNA oxidative damage by quantification of thymidine glycol residues using gas chromatography/electron capture negative ionization mass spectrometry.
Analytical biochemistry 1996;241(1):35-41.
1996: K Nishida; Sanford Markey
Nicardipine and MK-801 attenuate platelet-activating factor increases following cerebral ischemia-reperfusion in gerbils.
Brain research 1996;733(2):203-10.
1996: I N Mefford; L Kincl; K H Dykstra; J T Simpson; Sanford Markey; S Dietz; R Mark Wightman
Facile oxidative decarboxylation of 3,4-dihydroxyphenylacetic acid catalyzed by copper and manganese ions.
Biochimica et biophysica acta 1996;1290(3):224-30.
1996: K Nishida; Sanford Markey
Platelet-activating factor in brain regions after transient ischemia in gerbils.
Stroke; a journal of cerebral circulation 1996;27(3):514-8; discussion 518-9.
1996: Kuniaki Saito; M Seishima; A Noma; Y Nagamura; B J Quearry; Sanford Markey; M P Heyes
Kynurenine pathway metabolism in the galactosamine model of hepatic injury.
Advances in experimental medicine and biology 1996;398():421-4.
1996: Kuniaki Saito; M Seishima; A Noma; K Suyama; Sanford Markey; M P Heyes
4-chloro-3-hydroxyanthranilate attenuate quinolinic acid accumulation in brain following transient cerebral ischemia in the gerbil.
Advances in experimental medicine and biology 1996;398():407-11.
1996: Kuniaki Saito; M Seishima; A Noma; Sanford Markey; M P Heyes
Cytokine and drug modulation of kynurenine pathway metabolism by blood mononuclear cells.
Advances in experimental medicine and biology 1996;398():161-5.
1996: J T Simpson; D S Torok; J E Girard; Sanford Markey
Analysis of amino acids in biological fluids by pentafluorobenzyl chloroformate derivatization and detection by electron capture negative ionization mass spectrometry.
Analytical biochemistry 1996;233(1):58-66.
1996: K Nishida; Sanford Markey; Y Kustova; Herbert C Morse; Phil Skolnick; Anthony Basile; Yoshitatsu Sei
Increased brain levels of platelet-activating factor in a murine acquired immune deficiency syndrome are NMDA receptor-mediated.
Journal of neurochemistry 1996;66(1):433-5.
1995: D B Naritsin; K Saito; Sanford Markey; C Y Chen; Melvyn P Heyes
Metabolism of L-tryptophan to kynurenate and quinolinate in the central nervous system: effects of 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
Journal of neurochemistry 1995;65(5):2217-26.
1995: L N Daniel; Y Mao; T C Wang; C J Markey; Sanford Markey; Xianglin Shi; U Saffiotti
DNA strand breakage, thymine glycol production, and hydroxyl radical generation induced by different samples of crystalline silica in vitro.
Environmental research 1995;71(1):60-73.
1995: J C Porter; C F Ijames; T C Wang; Sanford Markey
Purification and identification of pituitary cytotropic factor.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5351-5.
1995: D B Naritsin; R L Boni; Sanford Markey
Pentafluorobenzylation method for quantification of acidic tryptophan metabolites using electron capture negative ion mass spectrometry.
Analytical chemistry 1995;67(5):863-70.
1994: K Saito; Sanford Markey; Melvyn P Heyes
6-Chloro-D,L-tryptophan, 4-chloro-3-hydroxyanthranilate and dexamethasone attenuate quinolinic acid accumulation in brain and blood following systemic immune activation.
Neuroscience letters 1994;178(2):211-5.
1994: Ryan Uitti; BJ Snow; H Shinotoh; FJ Vingerhoets; M Hayward; S Hashimoto; J Richmond; Sanford Markey; C J Markey; Donald B Calne
Parkinsonism induced by solvent abuse.
Annals of neurology 1994;35(5):616-9.
1994: R L Boni; J T Simpson; D B Naritsin; K Saito; Sanford Markey
Quantification of L-tryptophan and L-kynurenine by liquid chromatography/electron capture negative ion chemical ionization mass spectrometry.
Biological mass spectrometry 1994;23(1):27-32.
1993: Melvyn P Heyes; K Saito; E O Major; Sheldon Milstien; Sanford Markey; J H Vickers
A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
Brain : a journal of neurology 1993;116 ( Pt 6)():1425-50.
1993: K Saito; T S Nowak; K Suyama; B J Quearry; M Saito; J S Crowley; Sanford Markey; Melvyn P Heyes
Kynurenine pathway enzymes in brain: responses to ischemic brain injury versus systemic immune activation.
Journal of neurochemistry 1993;61(6):2061-70.
1993: Pim Brouwers; M P Heyes; H A Moss; Pamela L Wolters; David G Poplack; Sanford Markey; PA Pizzo
Quinolinic acid in the cerebrospinal fluid of children with symptomatic human immunodeficiency virus type 1 disease: relationships to clinical status and therapeutic response.
The Journal of infectious diseases 1993;168(6):1380-6.
1993: K Saito; B J Quearry; M Saito; T S Nowak; Sanford Markey; Melvyn P Heyes
Kynurenine 3-hydroxylase in brain: species activity differences and effect of gerbil cerebral ischemia.
Archives of biochemistry and biophysics 1993;307(1):104-9.
1993: O M Adeyemo; Moussa B H Youdim; Sanford Markey; C J Markey; Harvey B Pollard
L-deprenyl confers specific protection against MPTP-induced Parkinson's disease-like movement disorder in the goldfish.
European journal of pharmacology 1993;240(2-3):185-93.
1993: K Saito; J S Crowley; Sanford Markey; Melvyn P Heyes
A mechanism for increased quinolinic acid formation following acute systemic immune stimulation.
The Journal of biological chemistry 1993;268(21):15496-503.
1993: Sanford Markey; C J Markey; T C Wang
Oxidative damage in double-stranded genomic DNA as measured by GC/MS assay of a thymine glycol derivative.
Annals of the New York Academy of Sciences 1993;679():352-7.
1993: Harvey B Pollard; M Adeyemo; K Dhariwal; Mark Levine; Hung Caohuy; Sanford Markey; C J Markey; Moussa B H Youdim
The goldfish as a drug discovery vehicle for Parkinson's disease and other neurodegenerative disorders.
Annals of the New York Academy of Sciences 1993;679():317-20.
1993: K Saito; C Y Chen; M Masana; J S Crowley; Sanford Markey; Melvyn P Heyes
4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-gamma-stimulated monocytes (THP-1 cells).
The Biochemical journal 1993;291 ( Pt 1)():11-4.
1993: K Saito; T S Nowak; Sanford Markey; Melvyn P Heyes
Mechanism of delayed increases in kynurenine pathway metabolism in damaged brain regions following transient cerebral ischemia.
Journal of neurochemistry 1993;60(1):180-92.
1992: K Saito; Sanford Markey; Melvyn P Heyes
Effects of immune activation on quinolinic acid and neuroactive kynurenines in the mouse.
Neuroscience 1992;51(1):25-39.
1992: Harvey B Pollard; K Dhariwal; O M Adeyemo; C J Markey; Hung Caohuy; Mark Levine; Sanford Markey; Moussa B H Youdim
A parkinsonian syndrome induced in the goldfish by the neurotoxin MPTP.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992;6(12):3108-16.
1992: P J Todd; R T Short; C C Grimm; W M Holland; Sanford Markey
Organic ion imaging using tandem mass spectrometry.
Analytical chemistry 1992;64(17):1871-8.
1992: Melvyn P Heyes; B J Brew; K Saito; B J Quearry; R W Price; K Lee; R B Bhalla; Margaret Der; Sanford Markey
Inter-relationships between quinolinic acid, neuroactive kynurenines, neopterin and beta 2-microglobulin in cerebrospinal fluid and serum of HIV-1-infected patients.
Journal of neuroimmunology 1992;40(1):71-80.
1992: Melvyn P Heyes; K Saito; D Jacobowitz; Sanford Markey; O Takikawa; J H Vickers
Poliovirus induces indoleamine-2,3-dioxygenase and quinolinic acid synthesis in macaque brain.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992;6(11):2977-89.
1992: Melvyn P Heyes; K Saito; Sanford Markey
Human macrophages convert L-tryptophan into the neurotoxin quinolinic acid.
The Biochemical journal 1992;283 ( Pt 3)():633-5.
1992: M W Duncan; Ann M Marini; R Watters; Irwin J Kopin; Sanford Markey
Zinc, a neurotoxin to cultured neurons, contaminates cycad flour prepared by traditional guamanian methods.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(4):1523-37.
1992: H Ikeda; C J Markey; Sanford Markey
Search for neurotoxins structurally related to 1-methyl-4-phenylpyridine (MPP+) in the pathogenesis of Parkinson's disease.
Brain research 1992;575(2):285-98.
1992: M W Duncan; Sanford Markey; B G Weick; P G Pearson; H Ziffer; Y Hu; Irwin J Kopin
2-Amino-3-(methylamino)propanoic acid (BMAA) bioavailability in the primate.
Neurobiology of aging 1992;13(2):333-7.
1992: Moussa B H Youdim; K Dhariwal; Mark Levine; C J Markey; Sanford Markey; Hung Caohuy; O M Adeyemo; Harvey B Pollard
MPTP-induced "parkinsonism" in the goldfish.
Neurochemistry international 1992;20 Suppl():275S-278S.
1992: Melvyn P Heyes; E K Jordan; K Lee; K Saito; J A Frank; P J Snoy; Sanford Markey; M Gravell
Relationship of neurologic status in macaques infected with the simian immunodeficiency virus to cerebrospinal fluid quinolinic acid and kynurenic acid.
Brain research 1992;570(1-2):237-50.
1992: Alex Martin; Melvyn P Heyes; AM Salazar; D L Kampen; J Williams; W A Law; Michael E Coats; Sanford Markey
Progressive slowing of reaction time and increasing cerebrospinal fluid concentrations of quinolinic acid in HIV-infected individuals.
The Journal of neuropsychiatry and clinical neurosciences 1992;4(3):270-9.
1991: Sandra E Pike; Sanford Markey; C Ijames; K D Jones; Giovanna Tosato
The role of lactic acid in autocrine B-cell growth stimulation.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11081-5.
1991: J N Johannessen; T J Sobotka; V K Weise; Sanford Markey
Prolonged alterations in canine striatal dopamine metabolism following subtoxic doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 4'-amino-MPTP are linked to the persistence of pyridinium metabolites.
Journal of neurochemistry 1991;57(3):981-90.
1991: M W Duncan; N E Villacreses; P G Pearson; L Wyatt; Stanley I Rapoport; Irwin J Kopin; Sanford Markey; Q R Smith
2-amino-3-(methylamino)-propanoic acid (BMAA) pharmacokinetics and blood-brain barrier permeability in the rat.
The Journal of pharmacology and experimental therapeutics 1991;258(1):27-35.
1991: K Saito; Sanford Markey; Melvyn P Heyes
Chronic effects of gamma-interferon on quinolinic acid and indoleamine-2,3-dioxygenase in brain of C57BL6 mice.
Brain research 1991;546(1):151-4.
1991: K Saito; Andrew Lackner; Sanford Markey; Melvyn P Heyes
Cerebral cortex and lung indoleamine-2,3-dioxygenase activity is increased in type-D retrovirus infected macaques.
Brain research 1991;540(1-2):353-6.
1991: Melvyn P Heyes; K J Swartz; Sanford Markey; M Flint Beal
Regional brain and cerebrospinal fluid quinolinic acid concentrations in Huntington's disease.
Neuroscience letters 1991;122(2):265-9.
1991: Miles Herkenham; M D Little; K Bankiewicz; S C Yang; Sanford Markey; J N Johannessen
Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic study.
Neuroscience 1991;40(1):133-58.
1991: Melvyn P Heyes; B Brew; Alex Martin; Sanford Markey; R W Price; R B Bhalla; A Salazar
Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome.
Advances in experimental medicine and biology 1991;294():687-90.
1991: Melvyn P Heyes; A R Wyler; Orrin Devinsky; J A Yergey; Sanford Markey; N S Nadi
Brain and cerebrospinal fluid quinolinic acid concentrations in patients with intractable complex partial seizures.
Advances in experimental medicine and biology 1991;294():683-6.
1991: Matthew J During; M P Heyes; Andrew Freese; K J Swartz; Wayne R Matson; Sanford Markey; J B Martin; Robert H Roth
Indolic and kynurenine pathway metabolites of tryptophan in rat brain: effect of precursor availability on in vivo release.
Advances in experimental medicine and biology 1991;294():535-9.
1991: R L Boni; Melvyn P Heyes; J D Bacher; J A Yergey; X D Ji; Alfred Abramson; Sanford Markey
Stable isotope-labeled tryptophan as a precursor for studying the disposition of quinolinic acid in rabbits.
Advances in experimental medicine and biology 1991;294():481-4.
1991: Sanford Markey; R L Boni; J A Yergey; Melvyn P Heyes
Mass spectrometric determinations of tryptophan and its metabolites.
Advances in experimental medicine and biology 1991;294():41-50.
1991: Melvyn P Heyes; M Papagapiou; C Leonard; Sanford Markey; Roland Auer
Effects of profound insulin-induced hypoglycemia on quinolinic acid in hippocampus and plasma.
Advances in experimental medicine and biology 1991;294():679-82.
1991: Melvyn P Heyes; M Gravell; M April; D Blackmore; W T London; J A Yergey; Sanford Markey
Quinolinic acid concentrations are increased in cerebrospinal fluid of Rhesus macaques (Macaca mulatta) naturally infected with simian retrovirus type-D.
Advances in experimental medicine and biology 1991;294():555-8.
1990: Melvyn P Heyes; M Gravell; W T London; M Eckhaus; J H Vickers; J A Yergey; M April; D Blackmore; Sanford Markey
Sustained increases in cerebrospinal fluid quinolinic acid concentrations in rhesus macaques (Macaca mulatta) naturally infected with simian retrovirus type-D.
Brain research 1990;531(1-2):148-58.
1990: J N Johannessen; Sanford Markey
Characterization of 1-methyl-4-[4'-amino]phenyl-1,2,3,6-tetrahydropyridine toxicity in the mouse.
Biochemical pharmacology 1990;40(4):901-6.
1990: M W Duncan; J C Steele; Irwin J Kopin; Sanford Markey
2-Amino-3-(methylamino)-propanoic acid (BMAA) in cycad flour: an unlikely cause of amyotrophic lateral sclerosis and parkinsonism-dementia of Guam.
Neurology 1990;40(5):767-72.
1990: Melvyn P Heyes; A R Wyler; Orrin Devinsky; J A Yergey; Sanford Markey; N S Nadi
Quinolinic acid concentrations in brain and cerebrospinal fluid of patients with intractable complex partial seizures.
Epilepsia 1990;31(2):172-7.
1990: Melvyn P Heyes; M Papagapiou; C Leonard; Sanford Markey; Roland Auer
Brain and plasma quinolinic acid in profound insulin-induced hypoglycemia.
Journal of neurochemistry 1990;54(3):1027-33.
1990: J N Johannessen; David S Goldstein; J Oliver; Sanford Markey
Prolonged changes in plasma concentrations of catecholamine metabolites following a single infusion of an MPTP analog.
Life sciences 1990;47(21):1895-901.
1989: M Shih; T C Wang; Sanford Markey
Evaporation device for continuous flow liquid secondary ion mass spectrometry.
Analytical chemistry 1989;61(22):2582-3.
1989: M M Mourdian; Melvyn P Heyes; J B Pan; I J Heuser; Sanford Markey; Thomas N Chase; M M Mouradian
No changes in central quinolinic acid levels in Alzheimer's disease.
Neuroscience letters 1989;105(1-2):233-8.
1989: J N Johannessen; Chuang C Chiueh; J P Bacon; N A Garrick; R S Burns; V K Weise; Irwin J Kopin; Joseph E Parisi; Sanford Markey
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the dog: effect of pargyline pretreatment.
Journal of neurochemistry 1989;53(2):582-9.
1989: Melvyn P Heyes; David Rubinow; C Lane; Sanford Markey
Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome.
Annals of neurology 1989;26(2):275-7.
1989: Melvyn P Heyes; B J Quearry; Sanford Markey
Systemic endotoxin increases L-tryptophan, 5-hydroxyindoleacetic acid, 3-hydroxykynurenine and quinolinic acid content of mouse cerebral cortex.
Brain research 1989;491(1):173-9.
1989: M W Duncan; I J Kopin; J S Crowley; S M Jones; Sanford Markey
Quantification of the putative neurotoxin 2-amino-3-(methylamino)propanoic acid (BMAA) in cycadales: analysis of the seeds of some members of the family Cycadaceae.
Journal of analytical toxicology 1989;13(4):suppl A-G.
1989: T C Wang; M C Shih; Sanford Markey; M W Duncan
Quantitative analysis of low molecular weight polar compounds by continuous flow liquid secondary ion tandem mass spectrometry.
Analytical chemistry 1989;61(9):1013-6.
1989: Matthew J During; Andrew Freese; M P Heyes; K J Swartz; Sanford Markey; Robert H Roth; J B Martin
Neuroactive metabolites of L-tryptophan, serotonin and quinolinic acid, in striatal extracellular fluid. Effect of tryptophan loading.
FEBS letters 1989;247(2):438-44.
1989: Matthew J During; M P Heyes; Andrew Freese; Sanford Markey; J B Martin; Robert H Roth
Quinolinic acid concentrations in striatal extracellular fluid reach potentially neurotoxic levels following systemic L-tryptophan loading.
Brain research 1989;476(2):384-7.
1988: Melvyn P Heyes; P Kim; Sanford Markey
Systemic lipopolysaccharide and pokeweed mitogen increase quinolinic acid content of mouse cerebral cortex.
Journal of neurochemistry 1988;51(6):1946-8.
1988: S C Yang; Sanford Markey; Krystof Bankiewicz; W T London; G Lunn
Recommended safe practices for using the neurotoxin MPTP in animal experiments.
Laboratory animal science 1988;38(5):563-7.
1988: C F Masters; Sanford Markey; I N Mefford; M W Duncan
Separation of deuteriated isotopomers of dopamine by ion-pair reversed-phase high-performance liquid chromatography.
Analytical chemistry 1988;60(19):2131-4.
1988: Melvyn P Heyes; Sanford Markey
Quantification of quinolinic acid in rat brain, whole blood, and plasma by gas chromatography and negative chemical ionization mass spectrometry: effects of systemic L-tryptophan administration on brain and blood quinolinic acid concentrations.
Analytical biochemistry 1988;174(1):349-59.
1988: M W Duncan; I J Kopin; R M Garruto; L Lavine; Sanford Markey
2-Amino-3 (methylamino)-propionic acid in cycad-derived foods is an unlikely cause of amyotrophic lateral sclerosis/parkinsonism.
Lancet 1988;2(8611):631-2.
1988: S C Yang; J N Johannessen; Sanford Markey
Metabolism of [14C]MPTP in mouse and monkey implicates MPP+, and not bound metabolites, as the operative neurotoxin.
Chemical research in toxicology 1988;1(4):228-33.
1988: M P Heyes; Sanford Markey
(18O)quinolinic acid: its esterification without back exchange for use as internal standard in the quantification of brain and CSF quinolinic acid.
Biomedical & environmental mass spectrometry 1988;15(5):291-3.
1988: R N Golden; Sanford Markey; E D Risby; M V Rudorfer; R W Cowdry; William Z Potter
Antidepressants reduce whole-body norepinephrine turnover while enhancing 6-hydroxymelatonin output.
Archives of general psychiatry 1988;45(2):150-4.
1988: Melvyn P Heyes; B Hutto; Sanford Markey
4-chloro-3-hydroxyanthranilate inhibits brain 3-hydroxyanthranate oxidase.
Neurochemistry international 1988;13(3):405-8.
1988: Irwin J Kopin; Sanford Markey
MPTP toxicity: implications for research in Parkinson's disease.
Annual review of neuroscience 1988;11():81-96.
1987: C J Bojkowski; J Arendt; M C Shih; Sanford Markey
Melatonin secretion in humans assessed by measuring its metabolite, 6-sulfatoxymelatonin.
Clinical chemistry 1987;33(8):1343-8.
1987: J Yanovski; J Witcher; N Adler; Sanford Markey; David Klein
Stimulation of the paraventricular nucleus area of the hypothalamus elevates urinary 6-hydroxymelatonin during daytime.
Brain research bulletin 1987;19(1):129-33.
1987: J N Johannessen; Joseph M Savitt; C J Markey; J P Bacon; A Weisz; D S Hanselman; Sanford Markey
The development of amine substituted analogues of MPTP as unique tools for the study of MPTP toxicity and Parkinson's disease.
Life sciences 1987;40(8):697-704.
1987: S Higa; T Suzuki; S Sakoda; S Kishimoto; Y Takaba; A Nakajima; Sanford Markey
Disturbed function of the pineal gland in familial amyloid polyneuropathy.
Journal of neural transmission 1987;69(1-2):97-103.
1986: Sanford Markey; A Weisz; J P Bacon
Reduced paraquat does not exhibit MPTP-like neurotoxicity.
Journal of analytical toxicology 1986;10(6):257.
1986: Sanford Markey; N R Schmuff
The pharmacology of the parkinsonian syndrome producing neurotoxin MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and structurally related compounds.
Medicinal research reviews 1986;6(4):389-429.
1986: Alfred Abramson; Sanford Markey
Mass spectrometric analysis of sulfur in microgram quantities of biological macromolecules using a reaction interface.
Biomedical & environmental mass spectrometry 1986;13(8):411-5.
1986: Sanford Markey
Mass spectrometry: recent developments.
Journal of clinical pharmacology 1986;26(6):406-11.
1986: Alfred J Lewy; L J Siever; Thomas W Uhde; Sanford Markey
Clonidine reduces plasma melatonin levels.
The Journal of pharmacy and pharmacology 1986;38(7):555-6.
1986: J N Johannessen; J D Adams; H M Schuller; J P Bacon; Sanford Markey
1-Methyl-4-phenylpyridine (MPP+) induces oxidative stress in the rodent.
Life sciences 1986;38(8):743-9.
1986: M C Shih; Sanford Markey
Quantification of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion in brain tissue by gas chromatography/mass spectrometry.
Biomedical & environmental mass spectrometry 1986;13(2):85-9.
1986: Dennis L Murphy; N A Garrick; L Tamarkin; P L Taylor; Sanford Markey
Effects of antidepressants and other psychotropic drugs on melatonin release and pineal gland function.
Journal of neural transmission. Supplementum 1986;21():291-309.
1985: Sanford Markey; S Higa; M Shih; David N Danforth; L Tamarkin
The correlation between human plasma melatonin levels and urinary 6-hydroxymelatonin excretion.
Clinica chimica acta; international journal of clinical chemistry 1985;150(3):221-5.
1985: P A Taylor; N A Garrick; L Tamarkin; Dennis L Murphy; Sanford Markey
Diurnal rhythms of N-acetylserotonin and serotonin in cerebrospinal fluid of monkeys.
Science (New York, N.Y.) 1985;228(4701):900.
1985: J N Johannessen; Chuang C Chiueh; R S Burns; Sanford Markey
Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effects.
Life sciences 1985;36(3):219-24.
1985: C C Chiueh; R S Burns; Sanford Markey; D M Jacobowitz; I J Kopin
Primate model of parkinsonism: selective lesion of nigrostriatal neurons by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine produces an extrapyramidal syndrome in rhesus monkeys.
Life sciences 1985;36(3):213-8.
1985: J N Johannessen; L Kelner; D Hanselman; M C Shih; Sanford Markey
In vitro oxidation of MPTP by primate neural tissue: A potential model of MPTP neurotoxicity.
Neurochemistry international 1985;7(1):169-76.
1985: S Higa; Sanford Markey
Identification and quantification of 5-methoxyindole-3-acetic acid in human urine.
Analytical biochemistry 1985;144(1):86-93.
1984: David S Goldstein; R Stull; Sanford Markey; E S Marks; H R Keiser
Dihydrocaffeic acid: a common contaminant in the liquid chromatographic-electrochemical measurement of plasma catecholamines in man.
Journal of chromatography 1984;311(1):148-53.
1984: Sanford Markey; J N Johannessen; Chuang C Chiueh; R S Burns; M A Herkenham
Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism.
Nature 1984;311(5985):464-7.
1984: Peter R Martin; S Higa; R S Burns; L Tamarkin; M H Ebert; Sanford Markey
Decreased 6-hydroxymelatonin excretion in Korsakoff's psychosis.
Neurology 1984;34(7):966-8.
1984: J N Johannessen; Sanford Markey
Assessment of the opiate properties of two constituents of a toxic illicit drug mixture.
Drug and alcohol dependence 1984;13(4):367-74.
1984: Chuang C Chiueh; Sanford Markey; R S Burns; J N Johannessen; A Pert; Irwin J Kopin
Neurochemical and behavioral effects of systemic and intranigral administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the rat.
European journal of pharmacology 1984;100(2):189-94.
1984: R S Burns; Sanford Markey; J M Phillips; C C Chiueh
The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the monkey and man.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1984;11(1 Suppl):166-8.
1984: I J Kopin; P Blombery; M H Ebert; E K Gordon; D C Jimerson; Sanford Markey; R J Polinsky
Disposition and metabolism of MHPG-CD3 in humans: plasma MHPG as the principal pathway of norepinephrine metabolism and as an important determinant of CSF levels of MHPG.
Advances in biochemical psychopharmacology 1984;39():57-68.
1984: I J Kopin; D C Jimerson; Sanford Markey; M H Ebert; R J Polinsky
Disposition and metabolism of MHPG in humans: application to studies in depression.
Pharmacopsychiatry 1984;17(1):3-8.
1984: Chuang C Chiueh; Sanford Markey; R S Burns; J N Johannessen; D M Jacobowitz; Irwin J Kopin
Neurochemical and behavioral effects of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) in rat, guinea pig, and monkey.
Psychopharmacology bulletin 1984;20(3):548-53.
1983: N A Garrick; L Tamarkin; P L Taylor; Sanford Markey; Dennis L Murphy
Light and propranolol suppress the nocturnal elevation of serotonin in the cerebrospinal fluid of rhesus monkeys.
Science (New York, N.Y.) 1983;221(4609):474-6.
1983: R S Burns; C C Chiueh; Sanford Markey; M H Ebert; D M Jacobowitz; I J Kopin
A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(14):4546-50.
1983: M Zatz; S J Engelsen; Sanford Markey
Novel formation of S-methylacylthioester from oleoyl coenzyme A and S-adenosylmethionine in the presence of FeSO4.
The Journal of biological chemistry 1983;258(9):5759-63.
1983: D C Klein; R Smoot; joan weller; S Higa; Sanford Markey; G J Creed; D M Jacobowitz
Lesions of the paraventricular nucleus area of the hypothalamus disrupt the suprachiasmatic leads to spinal cord circuit in the melatonin rhythm generating system.
Brain research bulletin 1983;10(5):647-52.
1982: M Zatz; S J Engelsen; Sanford Markey
Biosynthesis of S-methyl-N-oleoylmercaptoethylamide from oleoyl coenzyme A and S-adenosylmethionine.
The Journal of biological chemistry 1982;257(22):13673-8.
1982: P L Taylor; N A Garrick; R S Burns; L Tamarkin; Dennis L Murphy; Sanford Markey
Diurnal rhythms of serotonin in monkey cerebrospinal fluid.
Life sciences 1982;31(18):1993-9.
1982: Alfred J Lewy; Thomas Wehr; N E Rosenthal; J I Nurnberger; L J Siever; Thomas W Uhde; D A Newsome; L E Becker; Sanford Markey; I J Kopin; F K Goodwin
Melatonin secretion as a neurobiological "marker" and effects of light in humans.
Psychopharmacology bulletin 1982;18(4):127-9.
1982: Sanford Markey; P E Buell
Pinealectomy abolishes 6-hydroxymelatonin excretion by male rats.
Endocrinology 1982;111(2):425-6.
1982: M Tetsuo; M Poth; Sanford Markey
Melatonin metabolite excretion during childhood and puberty.
The Journal of clinical endocrinology and metabolism 1982;55(2):311-3.
1982: Y Kloog; M Zatz; B Rivnay; P A Dudley; Sanford Markey
Nonpolar lipid methylation-identification of nonpolar methylated products synthesized by rat basophilic leukemia cells, retina and parotid.
Biochemical pharmacology 1982;31(5):753-9.
1982: M Tetsuo; MARK JACOB PERLOW; Mortimer Mishkin; Sanford Markey
Light exposure reduces and pinealectomy virtually stops urinary excretion of 6-hydroxymelatonin by rhesus monkeys.
Endocrinology 1982;110(3):997-1003.
1981: M Zatz; P A Dudley; Y Kloog; Sanford Markey
Nonpolar lipid methylation. Biosynthesis of fatty acid methyl esters by rat lung membranes using S-adenosylmethionine.
The Journal of biological chemistry 1981;256(19):10028-32.
1981: Sanford Markey
Quantitative mass spectrometry.
Biomedical mass spectrometry 1981;8(9):426-30.
1981: M Tetsuo; R J Polinsky; Sanford Markey; I J Kopin
Urinary 6-hydroxymelatonin excretion in patients with orthostatic hypotension.
The Journal of clinical endocrinology and metabolism 1981;53(3):607-10.
1981: Sanford Markey; R W Colburn; J N Johannessen
Efficient extraction and mass spectrometric assay of serotonin in biological fluids.
Biomedical mass spectrometry 1981;8(7):301-4.
1981: D C Jimerson; Sanford Markey; J A Oliver; I J Kopin
Simultaneous measurement of plasma 4-hydroxy-3-methoxyphenylethylene glycol and 3,4-dihydroxyphenylethylene glycol by gas chromatography mass spectrometry.
Biomedical mass spectrometry 1981;8(6):256-9.
1981: M Tetsuo; Sanford Markey; R W Colburn; I J Kopin
Quantitative analysis of 6-hydroxymelatonin in human urine by gas chromatography--negative chemical ionization mass spectrometry.
Analytical biochemistry 1981;110(1):208-15.
1981: S I Goodman; Sanford Markey
Diagnosis of organic acidemias by gas chromatography--mass spectrometry.
Laboratory and research methods in biology and medicine 1981;6():1-158.
1980: Alfred J Lewy; Thomas Wehr; F K Goodwin; D A Newsome; Sanford Markey
Light suppresses melatonin secretion in humans.
Science (New York, N.Y.) 1980;210(4475):1267-9.
1980: P A Blombery; I J Kopin; E K Gordon; Sanford Markey; M H Ebert
Conversion of MHPG to vanillylmandelic acid. Implications for the importance of urinary MHPG.
Archives of general psychiatry 1980;37(10):1095-8.
1980: M Tetsuo; Sanford Markey; I J Kopin
Measurement of 6-hydroxymelatonin in human urine and its diurnal variations.
Life sciences 1980;27(2):105-9.
1980: Alfred J Lewy; M Tetsuo; Sanford Markey; F K Goodwin; I J Kopin
Pinealectomy abolishes plasma melatonin in the rat.
The Journal of clinical endocrinology and metabolism 1980;50(1):204-5.
1979: Sanford Markey; R W Colburn; I J Kopin; R L Aamodt
Distribution and excretion in the rat and monkey of [82Br] bromocriptine.
The Journal of pharmacology and experimental therapeutics 1979;211(1):31-5.
1979: M E Sisak; Sanford Markey; R W Colburn; A P Zavadil; I J Kopin
Identification of 6-hydroxymelatonin in normal human urine by gas chromatography-mass spectrometry.
Life sciences 1979;25(9):803-6.
1978: Alfred J Lewy; Sanford Markey
Analysis of melatonin in human plasma by gas chromatography negative chemical ionization mass spectrometry.
Science (New York, N.Y.) 1978;201(4357):741-3.
1978: G Muscettola; F K Goodwin; W Z Potter; M M Claeys; Sanford Markey
Imipramine and desipramine in plasma and spinal fluid: relationship to clinical response and serotonin metabolism.
Archives of general psychiatry 1978;35(5):621-5.
1977: M Claeys; Sanford Markey; W Maenhaut
Variance analysis of error in selected ion monitoring assays using various internal standards. A practical study case.
Biomedical mass spectrometry 1977;4(2):122-8.
1976: M Claeys; G Muscettola; Sanford Markey
Simultaneous measurement of imipramine and desipramine by selected ion recording with deuterated internal standards.
Biomedical mass spectrometry 1976;3(3):110-6.
1976: E K Gordon; Sanford Markey; R L Sherman; I J Kopin
Conjugated 3,4 dihydroxy phenyl acetic acid (DOPAC) in human and monkey cerebrospinal fluid and rat brain and the effects of probenecid treatment.
Life sciences 1976;18(11):1285-92.
1975: J A Thompson; Sanford Markey; P V Fennessey
Gas-chromatographic/mass-spectrometric identification and quantitation of tetronic and deoxytetronic acids in urine from normal adults and neonates.
Clinical chemistry 1975;21(13):1892-8.
1975: J A Thompson; Sanford Markey
Quantitative metabolic profiling of urinary organic acids by gas chromatography-mass spectrometry: comparison of isolation methods.
Analytical chemistry 1975;47(8):1313-21.
1975: S I Goodman; Sanford Markey; P G Moe; B S Miles; C C Teng
Glutaric aciduria; a "new" disorder of amino acid metabolism.
Biochemical medicine 1975;12(1):12-21.
1974: P Vulliet; Sanford Markey; T G Tornabene
Identification of methoxyester artifacts produced by methanolic-HCI solvolysis of the cyclopropane fatty acids of the genus Yersinia.
Biochimica et biophysica acta 1974;348(2):299-301.
1974: Sanford Markey; D A Wenger
Mass spectra of complex molecules. I. Chemical ionization of sphingolipids.
Chemistry and physics of lipids 1974;12(3):182-200.
1973: T A Witten; S P Levine; M T Killian; P J Boyle; Sanford Markey
Gas-chromatographic-mass-spectrometric determination of urinary acid profiles of normal young adults. II. The effect of ethanol.
Clinical chemistry 1973;19(9):963-6.
1973: Sanford Markey
Identification of a reagent addition product in the silylation of mesoxalic acid.
Journal of chromatographic science 1973;11(8):417-8.
1973: T A Witten; S P Levine; J O King; Sanford Markey
Gas-chromatographic-mass-spectrometric determination of urinary acid profiles of normal young adults on a controlled diet.
Clinical chemistry 1973;19(6):586-9.
1971: Sanford Markey; T G Tornabene
Characterization of branched monounsaturated hydrocarbons of Sarcina lutea and Sarcina flava.
Lipids 1971;6(3):190-5.