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Huda Akil

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Adriana Medina; Richard M Myers; Alan Schatzberg; Audrey F Seasholtz; Vikram Sharma; Huda Akil; William Bunney; Sharon Burke; Stanley J Watson Jr
Glucocorticoid and mineralocorticoid receptor expression in the human hippocampus in major depressive disorder.
Jennifer A Cummings; Adam N Perry; Huda Akil; Sarah M Clinton; Jill B Becker
Male rats that differ in novelty exploration demonstrate distinct patterns of sexual behavior.
Elaine K Hebda-Bauer; Tracy A Simmons; James A Stewart; Andrew Sugg; Eren Ural; Stanley J Watson Jr; Qiang Wei; James L Beals; Huda Akil
3xTg-AD mice exhibit an activated central stress axis during early-stage pathology.

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2013: Adriana Medina; Richard M Myers; Alan Schatzberg; Audrey F Seasholtz; Vikram Sharma; Huda Akil; William Bunney; Sharon Burke; Stanley J Watson Jr
Glucocorticoid and mineralocorticoid receptor expression in the human hippocampus in major depressive disorder.
Journal of psychiatric research 2013;47(3):307-14.
2013: Jennifer A Cummings; Adam N Perry; Huda Akil; Sarah M Clinton; Jill B Becker
Male rats that differ in novelty exploration demonstrate distinct patterns of sexual behavior.
Behavioral neuroscience 2013;127(1):47-58.
2013: Elaine K Hebda-Bauer; Tracy A Simmons; James A Stewart; Andrew Sugg; Eren Ural; Stanley J Watson Jr; Qiang Wei; James L Beals; Huda Akil
3xTg-AD mice exhibit an activated central stress axis during early-stage pathology.
Journal of Alzheimer's disease : JAD 2013;33(2):407-22.
2012: Sarah M Clinton; Shelly B Flagel; Danielle N Simpson; Cortney A Turner; Stanley J Watson Jr; Huda Akil
Neonatal fibroblast growth factor treatment enhances cocaine sensitization.
Pharmacology, biochemistry, and behavior 2012;103(1):6-17.
2012: Cortney A Turner; Stanley J Watson Jr; Huda Akil
The fibroblast growth factor family: neuromodulation of affective behavior.
Neuron 2012;76(1):160-74.
2012: Cortney A Turner; Stanley J Watson Jr; Huda Akil
Fibroblast growth factor-2: an endogenous antidepressant and anxiolytic molecule?
Biological psychiatry 2012;72(4):254-5.
2012: M J García-Fuster; G S Parks; Stanley J Watson Jr; Huda Akil; S M Clinton; O Civelli
The melanin-concentrating hormone (MCH) system in an animal model of depression-like behavior.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2012;22(8):607-13.
2012: Nancy Capriles; Stanley J Watson Jr; Huda Akil
Individual differences in the improvement of cocaine-induced place preference response by the 5-HT2C receptor antagonist SB242084 in rats.
Psychopharmacology 2012;220(4):731-40.
2012: Qiang Wei; Limei Zhang; Hugh M Fentress; Elaine K Hebda-Bauer; Stanley J Watson Jr; Mary T Hoversten; Audrey F Seasholtz; Huda Akil
Early-life forebrain glucocorticoid receptor overexpression increases anxiety behavior and cocaine sensitization.
Biological psychiatry 2012;71(3):224-31.
2012: Ilan A Kerman; Sarah M Clinton; René Bernard; Huda Akil; Danielle N Simpson; Tracy A Bedrosian; Stanley J Watson Jr
Inborn differences in environmental reactivity predict divergent diurnal behavioral, endocrine, and gene expression rhythms.
Psychoneuroendocrinology 2012;37(2):256-69.
2012: Ilan A Kerman; Richard M Myers; Alan F Schatzberg; Huda Akil; Jack D Barchas; René Bernard; William E Bunney; Edward G Jones; Stanley J Watson Jr; Robert C Thompson
Evidence for transcriptional factor dysregulation in the dorsal raphe nucleus of patients with major depressive disorder.
Frontiers in neuroscience 2012;6():135.
2012: M Julia García-Fuster; S Taha Mahmood; Stanley J Watson Jr; Shelly B Flagel; Huda Akil
Cocaine withdrawal causes delayed dysregulation of stress genes in the hippocampus.
PloS one 2012;7(7):e42092.
2012: Rebecca K Simmons; Danielle N Simpson; Huda Akil; Jasmine L Howard; Sarah M Clinton
DNA methylation in the developing hippocampus and amygdala of anxiety-prone versus risk-taking rats.
Developmental neuroscience 2012;34(1):58-67.
2012: Pedro Adolfo Sequeira; David M Walsh; Stanley J Watson Jr; Huda Akil; William E Bunney; Preston M Cartagena; Prabhakara V Choudary; Edward G Jones; Jun Li; Ling Morgan; Richard M Myers; Alan F Schatzberg; Marquis P Vawter
Gene expression changes in the prefrontal cortex, anterior cingulate cortex and nucleus accumbens of mood disorders subjects that committed suicide.
PloS one 2012;7(4):e35367.
2011: Shelly B Flagel; K N Pickup; Huda Akil; C M Cameron; Stanley J Watson Jr; T E Robinson
A food predictive cue must be attributed with incentive salience for it to induce c-fos mRNA expression in cortico-striatal-thalamic brain regions.
Neuroscience 2011;196():80-96.
2011: Sarah M Clinton; Ilan Kerman; Hailey R Orr; Danielle N Simpson; Stanley J Watson Jr; Antony D Abraham; Tracy A Bedrosian; Huda Akil
Pattern of forebrain activation in high novelty-seeking rats following aggressive encounter.
Brain research 2011;1422():20-31.
2011: Ilan Kerman; Devin T Rosenthal; Antony D Abraham; Huda Akil; Tracy A Bedrosian; Sarah M Clinton; Stanley J Watson Jr
High novelty-seeking predicts aggression and gene expression differences within defined serotonergic cell groups.
Brain research 2011;1419():34-45.
2011: M Julia García-Fuster; S Taha Mahmood; Leah M Mayo; Robert C Thompson; Stanley J Watson Jr; Shelly B Flagel; Huda Akil
Decreased proliferation of adult hippocampal stem cells during cocaine withdrawal: possible role of the cell fate regulator FADD.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2011;36(11):2303-17.
2011: Sarah M Clinton; Susette Miller; John D H Stead; Stanley J Watson Jr; Huda Akil
Developmental underpinnings of differences in rodent novelty-seeking and emotional reactivity.
The European journal of neuroscience 2011;34(6):994-1005.
2011: Emily Moon; Richard M Myers; Brandi Rollins; Alan Schatzberg; Pedro Adolfo Sequeira; Huda Akil; Jack Barchas; William E Bunney; William Byerley; Lynn E DeLisi; Edward G Jones; Andrea Mesén; Stanley J Watson Jr; Marquis P Vawter
Lack of association to a NRG1 missense polymorphism in schizophrenia or bipolar disorder in a Costa Rican population.
Schizophrenia research 2011;131(1-3):52-7.
2011: Bruce S McEwen; Huda Akil
Introduction to social neuroscience: gene, environment, brain, body.
Annals of the New York Academy of Sciences 2011;1231():vii-ix.
2011: N Calvo; Marco Cecchi; Mohamed Kabbaj; Stanley J Watson Jr; Huda Akil
Differential effects of social defeat in rats with high and low locomotor response to novelty.
Neuroscience 2011;183():81-9.
2011: R Bernard; I A Kerman; Robert C Thompson; E G Jones; W E Bunney; J D Barchas; A F Schatzberg; R M Myers; Huda Akil; Stanley J Watson Jr
Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression.
Molecular psychiatry 2011;16(6):634-46.
2011: Cortney A Turner; Sarah M Clinton; Robert C Thompson; Stanley J Watson Jr; Huda Akil
Fibroblast growth factor-2 (FGF2) augmentation early in life alters hippocampal development and rescues the anxiety phenotype in vulnerable animals.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(19):8021-5.
2011: Kristen A Stedenfeld; Sarah M Clinton; Ilan Kerman; Huda Akil; Stanley J Watson Jr; Alan F Sved
Novelty-seeking behavior predicts vulnerability in a rodent model of depression.
Physiology & behavior 2011;103(2):210-6.
2011: Emine Eren-Koçak; Cortney A Turner; Stanley J Watson Jr; Huda Akil
Short-hairpin RNA silencing of endogenous fibroblast growth factor 2 in rat hippocampus increases anxiety behavior.
Biological psychiatry 2011;69(6):534-40.
2011: Huda Akil; Maryann E Martone; David C Van Essen
Challenges and opportunities in mining neuroscience data.
Science (New York, N.Y.) 2011;331(6018):708-12.
2011: Shelly B Flagel; Jeremy J Clark; Terry E Robinson; Leah Mayo; Alayna Czuj; Ingo Willuhn; Christina A Akers; Sarah M Clinton; Paul E M Phillips; Huda Akil
A selective role for dopamine in stimulus-reward learning.
Nature 2011;469(7328):53-7.
2011: Jennifer A Cummings; Brooke A Gowl; Christel Westenbroek; Sarah M Clinton; Huda Akil; Jill B Becker
Effects of a selectively bred novelty-seeking phenotype on the motivation to take cocaine in male and female rats.
Biology of sex differences 2011;2():3.
2011: Paul R Burghardt; Shelly B Flagel; Kyle J Burghardt; steven britton; Lauren Gerard-Koch; Stanley J Watson Jr; Huda Akil
Risk-assessment and coping strategies segregate with divergent intrinsic aerobic capacity in rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2011;36(2):390-401.
2010: David M Krolewski; Adriana Medina; Ilan Kerman; Rene Bernard; Sharon Burke; Robert C Thompson; William E Bunney; Alan F Schatzberg; Richard Myers; Huda Akil; Edward G Jones; Stanley J Watson Jr
Expression patterns of corticotropin-releasing factor, arginine vasopressin, histidine decarboxylase, melanin-concentrating hormone, and orexin genes in the human hypothalamus.
The Journal of comparative neurology 2010;518(22):4591-611.
2010: Elaine K Hebda-Bauer; A Pletsch; H Darwish; H Fentress; T A Simmons; Qiang Wei; Stanley J Watson Jr; Huda Akil
Forebrain glucocorticoid receptor overexpression increases environmental reactivity and produces a stress-induced spatial discrimination deficit.
Neuroscience 2010;169(2):645-53.
2010: Colleen M Novak; Carlos Escande; Paul R Burghardt; Minzhi Zhang; Maria Teresa Barbosa; Eduardo N Chini; steven britton; Lauren G Koch; Huda Akil; James A Levine
Spontaneous activity, economy of activity, and resistance to diet-induced obesity in rats bred for high intrinsic aerobic capacity.
Hormones and behavior 2010;58(3):355-67.
2010: Sarah M Clinton; Tracy A Bedrosian; Antony D Abraham; Stanley J Watson Jr; Huda Akil
Neural and environmental factors impacting maternal behavior differences in high- versus low-novelty-seeking rats.
Hormones and behavior 2010;57(4-5):463-73.
2010: Huda Akil; Sydney Brenner; Eric R Kandel; Kenneth S Kendler; Mary-Claire King; Edward Scolnick; James D Watson; Huda Y Zoghbi
Medicine. The future of psychiatric research: genomes and neural circuits.
Science (New York, N.Y.) 2010;327(5973):1580-1.
2010: Maria Garcia-Fuster; J A Perez; Sarah M Clinton; Stanley J Watson Jr; Huda Akil
Impact of cocaine on adult hippocampal neurogenesis in an animal model of differential propensity to drug abuse.
The European journal of neuroscience 2010;31(1):79-89.
2010: Shelly B Flagel; Terry E Robinson; Jeremy J Clark; Sarah M Clinton; Stanley J Watson Jr; Phillip Seeman; Paul E M Phillips; Huda Akil
An animal model of genetic vulnerability to behavioral disinhibition and responsiveness to reward-related cues: implications for addiction.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(2):388-400.
2009: Huda Akil; Stanley J Watson Jr; Gregory Dalack; John F Greden; Jon K Zubieta
In memory of Elizabeth Young.
Biological psychiatry 2009;66(11):e25-6.
2009: Simon J Evans; Huda Akil; Stanley J Watson Jr
Analyzing gene expression in depression.
The American journal of psychiatry 2009;166(9):961-3.
2009: Javier A Perez; Sarah M Clinton; Cortney A Turner; Stanley J Watson Jr; Huda Akil
A new role for FGF2 as an endogenous inhibitor of anxiety.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(19):6379-87.
2009: Laura J Scott; Pierandrea Muglia; Xiangyang Q Kong; Weihua Guan; Matthew Flickinger; Ruchi Upmanyu; Federica Tozzi; Jun Z Li; Margit Burmeister; Devin Absher; Robert C Thompson; Clyde Francks; Fan Meng; Athos Antoniades; Audrey M Southwick; Alan F Schatzberg; William E Bunney; Jack D Barchas; Edward G Jones; Richard Day; Keith Matthews; Peter McGuffin; John S Strauss; James L Kennedy; Lefkos Middleton; Allen D Roses; Stanley J Watson Jr; John B Vincent; Richard Myers; Ann E Farmer; Huda Akil; Daniel K Burns; Michael Boehnke
Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(18):7501-6.
2009: Maria Garcia-Fuster; Sarah M Clinton; Stanley J Watson Jr; Huda Akil
Effect of cocaine on Fas-associated protein with death domain in the rat brain: individual differences in a model of differential vulnerability to drug abuse.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(5):1123-34.
2009: René Bernard; Ilan Kerman; Fan Meng; Simon J Evans; Irmgard Amrein; Edward G Jones; William E Bunney; Huda Akil; Stanley J Watson Jr; Robert C Thompson
Gene expression profiling of neurochemically defined regions of the human brain by in situ hybridization-guided laser capture microdissection.
Journal of neuroscience methods 2009;178(1):46-54.
2009: Cortney A Turner; Nancy Capriles; Shelly B Flagel; Javier A Perez; Sarah M Clinton; Stanley J Watson Jr; Huda Akil
Neonatal FGF2 alters cocaine self-administration in the adult rat.
Pharmacology, biochemistry, and behavior 2009;92(1):100-4.
2009: Maureen V Martin; Brandi Rollins; Pedro Adolfo Sequeira; Andrea Mesén; William Byerley; Richard Stein; Emily A Moon; Huda Akil; Edward G Jones; Stanley J Watson Jr; Jack Barchas; Lynn E DeLisi; Richard Myers; Alan Schatzberg; William E Bunney; Marquis P Vawter
Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation.
BMC medical genomics 2009;2():62.
2009: Brandi Rollins; Maureen V Martin; Pedro Adolfo Sequeira; Emily A Moon; Ling Z Morgan; Stanley J Watson Jr; Alan Schatzberg; Huda Akil; Richard Myers; Edward G Jones; Douglas C Wallace; William E Bunney; Marquis P Vawter
Mitochondrial variants in schizophrenia, bipolar disorder, and major depressive disorder.
PloS one 2009;4(3):e4913.
2009: Sara L Wright; Scott A Langenecker; Patricia J Deldin; Lisa J Rapport; Kristy A Nielson; Allison M Kade; Lawrence S Own; Huda Akil; Elizabeth A Young; Jon K Zubieta
Gender-specific disruptions in emotion processing in younger adults with depression.
Depression and anxiety 2009;26(2):182-9.
2009: Shelly B Flagel; Huda Akil; Terry E Robinson
Individual differences in the attribution of incentive salience to reward-related cues: Implications for addiction.
Neuropharmacology 2009;56 Suppl 1():139-48.
2008: Marco Cecchi; N Capriles; Stanley J Watson Jr; Huda Akil
Differential responses to morphine-induced analgesia in the tail-flick test.
Behavioural brain research 2008;194(2):146-51.
2008: Cortney A Turner; Shelly B Flagel; Sarah M Clinton; Huda Akil; Stanley J Watson Jr
Cocaine interacts with the novelty-seeking trait to modulate FGFR1 gene expression in the rat.
Neuroscience letters 2008;446(2-3):105-7.
2008: Lisa A Briand; Shelly B Flagel; Maria Garcia-Fuster; Stanley J Watson Jr; Huda Akil; Martin Sarter; Terry E Robinson
Persistent alterations in cognitive function and prefrontal dopamine D2 receptors following extended, but not limited, access to self-administered cocaine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(12):2969-80.
2008: Daniel Gardner; Huda Akil; Giorgio A Ascoli; Douglas M Bowden; William Bug; Duncan E Donohue; David H Goldberg; Bernice Grafstein; Jeffrey S Grethe; Amarnath Gupta; Maryam Halavi; David Nelson Kennedy; Luis Marenco; Maryann E Martone; Perry L Miller; Hans-Michael Müller; Adrian Robert; Gordon M Shepherd; Paul W Sternberg; David C Van Essen; Robert Williams
The neuroscience information framework: a data and knowledge environment for neuroscience.
Neuroinformatics 2008;6(3):149-60.
2008: Brooke A Davis; Sarah M Clinton; Huda Akil; Jill B Becker
The effects of novelty-seeking phenotypes and sex differences on acquisition of cocaine self-administration in selectively bred High-Responder and Low-Responder rats.
Pharmacology, biochemistry, and behavior 2008;90(3):331-8.
2008: Cortney A Turner; Edny L Gula; Larry P Taylor; Stanley J Watson Jr; Huda Akil
Antidepressant-like effects of intracerebroventricular FGF2 in rats.
Brain research 2008;1224():63-8.
2008: Heidi E W Day; Elisa M Kryskow; Stanley J Watson Jr; Huda Akil; Serge Campeau
Regulation of hippocampal alpha1d adrenergic receptor mRNA by corticosterone in adrenalectomized rats.
Brain research 2008;1218():132-40.
2008: A Jama; M Cecchi; N Calvo; Stanley J Watson Jr; Huda Akil
Inter-individual differences in novelty-seeking behavior in rats predict differential responses to desipramine in the forced swim test.
Psychopharmacology 2008;198(3):333-40.
2008: Santiago Jesus Ballaz; Huda Akil; Stanley J Watson Jr
The CCK-system underpins novelty-seeking behavior in the rat: gene expression and pharmacological analyses.
Neuropeptides 2008;42(3):245-53.
2008: Huda Akil; N J Coupe; J Singh
Spinal deposits of a benign choroid plexus papilloma.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2008;15(6):708-12.
2008: Pedro Adolfo Sequeira; Fan Meng; B Rollins; Richard Myers; E G Jones; Stanley J Watson Jr; Huda Akil; A F Schatzberg; J Barchas; W E Bunney; M P Vawter
Coding SNPs included in exon arrays for the study of psychiatric disorders.
Molecular psychiatry 2008;13(4):363-5.
2008: B C McKinney; Jay S Schneider; G L Schafer; J L Lowing; S Mohan; M X Zhao; M Y Heng; Roger L Albin; Audrey F Seasholtz; Huda Akil; Geoffrey G Murphy
Decreased locomotor activity in mice expressing tTA under control of the CaMKII alpha promoter.
Genes, brain, and behavior 2008;7(2):203-13.
2008: Sarah M Clinton; Susette Miller; Stanley J Watson Jr; Huda Akil
Prenatal stress does not alter innate novelty-seeking behavioral traits, but differentially affects individual differences in neuroendocrine stress responsivity.
Psychoneuroendocrinology 2008;33(2):162-77.
2008: Cortney A Turner; Nelson Calvo; Douglas O Frost; Huda Akil; Stanley J Watson Jr
The fibroblast growth factor system is downregulated following social defeat.
Neuroscience letters 2008;430(2):147-50.
2008: Shelly B Flagel; Stanley J Watson Jr; Huda Akil; Terry E Robinson
Individual differences in the attribution of incentive salience to a reward-related cue: influence on cocaine sensitization.
Behavioural brain research 2008;186(1):48-56.
2008: Huda Akil; Simon J Evans; Cortney A Turner; J Perez; Richard Myers; W E Bunney; E G Jones; Stanley J Watson Jr
The fibroblast growth factor family and mood disorders.
Novartis Foundation symposium 2008;289():94-6; discussion 97-100, 193-5.
2008: Ling Shao; Maureen V Martin; Stanley J Watson Jr; Alan Schatzberg; Huda Akil; Richard Myers; Edward G Jones; William E Bunney; Marquis P Vawter
Mitochondrial involvement in psychiatric disorders.
Annals of medicine 2008;40(4):281-95.
2007: Ilan Kerman; René Bernard; Devin Rosenthal; James Beals; Huda Akil; Stanley J Watson Jr
Distinct populations of presympathetic-premotor neurons express orexin or melanin-concentrating hormone in the rat lateral hypothalamus.
The Journal of comparative neurology 2007;505(5):586-601.
2007: Elaine K Hebda-Bauer; J Luo; Stanley J Watson Jr; Huda Akil
Female CREBalphadelta- deficient mice show earlier age-related cognitive deficits than males.
Neuroscience 2007;150(2):260-72.
2007: Adriaan M Karssen; Song Her; Jun Z Li; Paresh D Patel; Fan Meng; William E Bunney; Edward G Jones; Stanley J Watson Jr; Huda Akil; Richard Myers; Alan F Schatzberg; David M Lyons
Stress-induced changes in primate prefrontal profiles of gene expression.
Molecular psychiatry 2007;12(12):1089-102.
2007: Scott A Langenecker; Susan E Kennedy; Leslie M Guidotti Breting; Emily M Briceno; Lawrence S Own; Thomas Hooven; Elizabeth A Young; Huda Akil; Douglas Noll; Jon K Zubieta
Frontal and limbic activation during inhibitory control predicts treatment response in major depressive disorder.
Biological psychiatry 2007;62(11):1272-80.
2007: Santiago Jesus Ballaz; Huda Akil; Stanley J Watson Jr
The CCK-system mediates adaptation to novelty-induced stress in the rat: a pharmacological evidence.
Neuroscience letters 2007;428(1):27-32.
2007: Scott A Langenecker; Jon K Zubieta; Elizabeth A Young; Huda Akil; Kristy A Nielson
A task to manipulate attentional load, set-shifting, and inhibitory control: convergent validity and test-retest reliability of the Parametric Go/No-Go Test.
Journal of clinical and experimental neuropsychology 2007;29(8):842-53.
2007: Santiago Jesus Ballaz; Huda Akil; Stanley J Watson Jr
The 5-HT7 receptor: role in novel object discrimination and relation to novelty-seeking behavior.
Neuroscience 2007;149(1):192-202.
2007: Santiago Jesus Ballaz; Huda Akil; Stanley J Watson Jr
Previous experience affects subsequent anxiety-like responses in rats bred for novelty seeking.
Behavioral neuroscience 2007;121(5):1113-8.
2007: Qiang Wei; Elaine K Hebda-Bauer; Amy Pletsch; Jie Luo; Mary T Hoversten; Andrew J Osetek; Simon J Evans; Stanley J Watson Jr; Audrey F Seasholtz; Huda Akil
Overexpressing the glucocorticoid receptor in forebrain causes an aging-like neuroendocrine phenotype and mild cognitive dysfunction.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(33):8836-44.
2007: Mary E Atz; David Walsh; Preston Cartagena; Jun Li; Simon J Evans; Prabhakara V Choudary; Kevin Overman; Richard Stein; Hiro Tomita; Steven G Potkin; Rick Myers; Stanley J Watson Jr; Edward G Jones; Huda Akil; William E Bunney; Marquis P Vawter
Methodological considerations for gene expression profiling of human brain.
Journal of neuroscience methods 2007;163(2):295-309.
2007: Santiago Jesus Ballaz; Huda Akil; Stanley J Watson Jr
Analysis of 5-HT6 and 5-HT7 receptor gene expression in rats showing differences in novelty-seeking behavior.
Neuroscience 2007;147(2):428-38.
2007: Bradley J Buck; Ilan Kerman; Paul R Burghardt; Lauren G Koch; steven britton; Huda Akil; Stanley J Watson Jr
Upregulation of GAD65 mRNA in the medulla of the rat model of metabolic syndrome.
Neuroscience letters 2007;419(2):178-83.
2007: Sarah M Clinton; Delia M Vázquez; Mohamed Kabbaj; Marie-Helen Kabbaj; Stanley J Watson Jr; Huda Akil
Individual differences in novelty-seeking and emotional reactivity correlate with variation in maternal behavior.
Hormones and behavior 2007;51(5):655-64.
2007: Shelly B Flagel; Stanley J Watson Jr; Terry E Robinson; Huda Akil
Individual differences in the propensity to approach signals vs goals promote different adaptations in the dopamine system of rats.
Psychopharmacology 2007;191(3):599-607.
2007: Aaron M Rozeboom; Huda Akil; Audrey F Seasholtz
Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(11):4688-93.
2007: Marco Cecchi; Nancy Capriles; Stanley J Watson Jr; Huda Akil
Beta1 adrenergic receptors in the bed nucleus of stria terminalis mediate differential responses to opiate withdrawal.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(3):589-99.
2007: Jun Z Li; Fan Meng; Larisa Tsavaler; Simon J Evans; Prabhakara V Choudary; Hiroaki Tomita; Marquis P Vawter; David Walsh; Vida Shokoohi; Tisha Chung; William E Bunney; Edward G Jones; Huda Akil; Stanley J Watson Jr; Richard Myers
Sample matching by inferred agonal stress in gene expression analyses of the brain.
BMC genomics 2007;8():336.
2007: Elzbieta Sliwerska; Fan Meng; Terence P Speed; Edward G Jones; William E Bunney; Huda Akil; Stanley J Watson Jr; Margit Burmeister
SNPs on chips: the hidden genetic code in expression arrays.
Biological psychiatry 2007;61(1):13-6.
2006: Ilan Kerman; Cyrus Shabrang; Larry Taylor; Huda Akil; Stanley J Watson Jr
Relationship of presympathetic-premotor neurons to the serotonergic transmitter system in the rat brainstem.
The Journal of comparative neurology 2006;499(6):882-96.
2006: John D H Stead; Sarah M Clinton; Charles Neal; Johanna Schneider; Abas Jama; Susette Miller; Delia M Vazquez; Stanley J Watson Jr; Huda Akil
Selective breeding for divergence in novelty-seeking traits: heritability and enrichment in spontaneous anxiety-related behaviors.
Behavior genetics 2006;36(5):697-712.
2006: Marquis P Vawter; Hiroaki Tomita; Fan Meng; B Bolstad; Jun Li; Simon J Evans; Prabhakara V Choudary; Mary E Atz; L Shao; C Neal; David M Walsh; Margit Burmeister; T Speed; Rick Myers; Edward G Jones; Stanley J Watson Jr; Huda Akil; William E Bunney
Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders.
Molecular psychiatry 2006;11(7):615, 663-79.
2006: Cortney A Turner; Huda Akil; Stanley J Watson Jr; Simon J Evans
The fibroblast growth factor system and mood disorders.
Biological psychiatry 2006;59(12):1128-35.
2006: Ilan Kerman; Bradley J Buck; Simon J Evans; Huda Akil; Stanley J Watson Jr
Combining laser capture microdissection with quantitative real-time PCR: effects of tissue manipulation on RNA quality and gene expression.
Journal of neuroscience methods 2006;153(1):71-85.
2006: Ilan Kerman; Huda Akil; Stanley J Watson Jr
Rostral elements of sympatho-motor circuitry: a virally mediated transsynaptic tracing study.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(13):3423-33.
2006: Adriaan M Karssen; Jun Z Li; Song Her; Paresh D Patel; Fan Meng; Simon J Evans; Marquis P Vawter; Hiroaki Tomita; Prabhakara V Choudary; William E Bunney; Edward G Jones; Stanley J Watson Jr; Huda Akil; Richard Myers; Alan F Schatzberg; David M Lyons
Application of microarray technology in primate behavioral neuroscience research.
Methods (San Diego, Calif.) 2006;38(3):227-34.
2006: John D H Stead; Charles Neal; Fan Meng; Yongjia Wang; Simon J Evans; Delia M Vazquez; Stanley J Watson Jr; Huda Akil
Transcriptional profiling of the developing rat brain reveals that the most dramatic regional differentiation in gene expression occurs postpartum.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(1):345-53.
2005: Prabhakara V Choudary; Margherita Molnar; Simon J Evans; H Tomita; J Z Li; Marquis P Vawter; Richard Myers; William E Bunney; Huda Akil; Stanley J Watson Jr; Edward G Jones
Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(43):15653-8.
2005: Elaine K Hebda-Bauer; Stanley J Watson Jr; Huda Akil
Cognitive performance is highly sensitive to prior experience in mice with a learning and memory deficit: failure leads to more failure.
Learning & memory (Cold Spring Harbor, N.Y.) 2005;12(5):461-71.
2005: Huda Akil
Stressed and depressed.
Nature medicine 2005;11(2):116-8.
2005: Manhong Dai; Pinglang Wang; Andrew Boyd; Georgi Kostov; Brian D Athey; Edward G Jones; William E Bunney; Richard Myers; Terence P Speed; Huda Akil; Stanley J Watson Jr; Fan Meng
Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data.
Nucleic acids research 2005;33(20):e175.
2005: Dana L Helmreich; David B Parfitt; Xin Yun Lu; Huda Akil; Stanley J Watson Jr
Relation between the hypothalamic-pituitary-thyroid (HPT) axis and the hypothalamic-pituitary-adrenal (HPA) axis during repeated stress.
Neuroendocrinology 2005;81(3):183-92.
2005: Kun-Ruey Shieh; Shu-Chuan Yang; Xin Yun Lu; Huda Akil; Stanley J Watson Jr
Diurnal rhythmic expression of the rhythm-related genes, rPeriod1, rPeriod2, and rClock, in the rat brain.
Journal of biomedical science 2005;12(1):209-17.
2004: Simon J Evans; Prabhakara V Choudary; Charles R Neal; J Z Li; Marquis P Vawter; H Tomita; Juan F Lopez; Robert C Thompson; Fan Meng; John D H Stead; D M Walsh; Richard Myers; William E Bunney; Stanley J Watson Jr; Edward G Jones; Huda Akil
Dysregulation of the fibroblast growth factor system in major depression.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(43):15506-11.
2004: Qiang Wei; Xin Yun Lu; Li Liu; Gwen Schafer; Kun-Ruey Shieh; Sharon Burke; Terry E Robinson; Stanley J Watson Jr; Audrey F Seasholtz; Huda Akil
Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11851-6.
2004: Elaine K Hebda-Bauer; Stanley J Watson Jr; Huda Akil
CREB deficient mice show inhibition and low activity in novel environments without changes in stress reactivity.
The European journal of neuroscience 2004;20(2):503-13.
2004: Jun Z Li; Marquis P Vawter; David M Walsh; Hiroaki Tomita; Simon J Evans; Prabhakara V Choudary; Juan F Lopez; Abigail Avelar; Vida Shokoohi; Tisha Chung; Omar Mesarwi; Edward G Jones; Stanley J Watson Jr; Huda Akil; William E Bunney; Richard Myers
Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions.
Human molecular genetics 2004;13(6):609-16.
2004: Hiroaki Tomita; Marquis P Vawter; David M Walsh; Simon J Evans; Prabhakara V Choudary; Jun Li; Kevin Overman; Mary E Atz; Richard Myers; Edward G Jones; Stanley J Watson Jr; Huda Akil; William E Bunney
Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain.
Biological psychiatry 2004;55(4):346-52.
2004: Antonio L López-Figueroa; Camille S Norton; Manuel O López-Figueroa; Denise Armellini-Dodel; Sharon Burke; Huda Akil; Juan F Lopez; Stanley J Watson Jr
Serotonin 5-HT1A, 5-HT1B, and 5-HT2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia.
Biological psychiatry 2004;55(3):225-33.
2004: Marquis P Vawter; Simon J Evans; Prabhakara V Choudary; Hiroaki Tomita; James Meador-Woodruff; Margherita Molnar; Jun Li; Juan F Lopez; Rick Myers; David Cox; Stanley J Watson Jr; Huda Akil; Edward G Jones; William E Bunney
Gender-specific gene expression in post-mortem human brain: localization to sex chromosomes.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(2):373-84.
2004: Mohamed Kabbaj; Simon J Evans; Stanley J Watson Jr; Huda Akil
The search for the neurobiological basis of vulnerability to drug abuse: using microarrays to investigate the role of stress and individual differences.
Neuropharmacology 2004;47 Suppl 1():111-22.
2004: Ceylan Isgor; Mohamed Kabbaj; Huda Akil; Stanley J Watson Jr
Delayed effects of chronic variable stress during peripubertal-juvenile period on hippocampal morphology and on cognitive and stress axis functions in rats.
Hippocampus 2004;14(5):636-48.
2004: Suzanne Erb; Douglas Funk; S Borkowski; Stanley J Watson Jr; Huda Akil
Effects of chronic cocaine exposure on corticotropin-releasing hormone binding protein in the central nucleus of the amygdala and bed nucleus of the stria terminalis.
Neuroscience 2004;123(4):1003-9.
2003: Simon J Evans; Stanley J Watson Jr; Huda Akil
Evaluation of sensitivity, performance and reproducibility of microarray technology in neuronal tissue.
Integrative and comparative biology 2003;43(6):780-5.
2003: Simon J Evans; Prabhakara V Choudary; Marquis P Vawter; J Li; James Meador-Woodruff; Juan F Lopez; S M Burke; Robert C Thompson; Richard Myers; E G Jones; William E Bunney; Stanley J Watson Jr; Huda Akil
DNA microarray analysis of functionally discrete human brain regions reveals divergent transcriptional profiles.
Neurobiology of disease 2003;14(2):240-50.
2003: Caurnel Morgan; Henryk F Urbanski; Wei Fan; Huda Akil; Roger D Cone
Pheromone-induced anorexia in male Syrian hamsters.
American journal of physiology. Endocrinology and metabolism 2003;285(5):E1028-38.
2003: Gavan P McNally; Huda Akil
Selective down-regulation of hippocampal glucocorticoid receptors during opiate withdrawal.
Brain research. Molecular brain research 2003;118(1-2):152-5.
2003: Caurnel Morgan; Robert C Thompson; Stanley J Watson Jr; Huda Akil
Syrian hamster proopiomelanocortin cDNA cloning and early seasonal changes in testicular expression.
General and comparative endocrinology 2003;133(3):353-7.
2003: Xin Yun Lu; Gregory S Barsh; Huda Akil; Stanley J Watson Jr
Interaction between alpha-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(21):7863-72.
2003: Charles R Neal; Constance E Owens; Larry P Taylor; Mary T Hoversten; Huda Akil; Stanley J Watson Jr
Binding and GTPgammaS autoradiographic analysis of preproorphanin precursor peptide products at the ORL1 and opioid receptors.
Journal of chemical neuroanatomy 2003;25(4):233-47.
2003: Susan M Ferguson; Camille S Norton; Stanley J Watson Jr; Huda Akil; Terry E Robinson
Amphetamine-evoked c-fos mRNA expression in the caudate-putamen: the effects of DA and NMDA receptor antagonists vary as a function of neuronal phenotype and environmental context.
Journal of neurochemistry 2003;86(1):33-44.
2003: Ceylan Isgor; Kun-Ruey Shieh; Huda Akil; Stanley J Watson Jr
Colocalization of estrogen beta-receptor messenger RNA with orphanin FQ, vasopressin and oxytocin in the rat hypothalamic paraventricular and supraoptic nuclei.
Anatomy and embryology 2003;206(6):461-9.
2003: Nakia S Gordon; Sharon Burke; Huda Akil; Stanley J Watson Jr; Jaak Panksepp
Socially-induced brain 'fertilization': play promotes brain derived neurotrophic factor transcription in the amygdala and dorsolateral frontal cortex in juvenile rats.
Neuroscience letters 2003;341(1):17-20.
2003: William E Bunney; Blynn G Bunney; Marquis P Vawter; Hiroaki Tomita; Jun Li; Simon J Evans; Prabhakara V Choudary; Richard Myers; Edward G Jones; Stanley J Watson Jr; Huda Akil
Microarray technology: a review of new strategies to discover candidate vulnerability genes in psychiatric disorders.
The American journal of psychiatry 2003;160(4):657-66.
2003: Jason M Uslaner; Camille S Norton; Stanley J Watson Jr; Huda Akil; Terry E Robinson
Amphetamine-induced c-fos mRNA expression in the caudate-putamen and subthalamic nucleus: interactions between dose, environment, and neuronal phenotype.
Journal of neurochemistry 2003;85(1):105-14.
2003: Ceylan Isgor; Marco Cecchi; Mohamed Kabbaj; Huda Akil; Stanley J Watson Jr
Estrogen receptor beta in the paraventricular nucleus of hypothalamus regulates the neuroendocrine response to stress and is regulated by corticosterone.
Neuroscience 2003;121(4):837-45.
2003: Michelle M Ostrander; Aldo Badiani; Heidi E W Day; Camille S Norton; Stanley J Watson Jr; Huda Akil; Terry E Robinson
Environmental context and drug history modulate amphetamine-induced c-fos mRNA expression in the basal ganglia, central extended amygdala, and associated limbic forebrain.
Neuroscience 2003;120(2):551-71.
2003: Darragh P Devine; M T Hoversten; Y Ueda; Huda Akil
Nociceptin/orphanin FQ content is decreased in forebrain neurones during acute stress.
Journal of neuroendocrinology 2003;15(1):69-74.
2003: Elizabeth A Young; Juan F Lopez; Virginia Murphy-Weinberg; Stanley J Watson Jr; Huda Akil
Mineralocorticoid receptor function in major depression.
Archives of general psychiatry 2003;60(1):24-8.
2002: Ceylan Isgor; Grace C Huang; Huda Akil; Stanley J Watson Jr
Correlation of estrogen beta-receptor messenger RNA with endogenous levels of plasma estradiol and progesterone in the female rat hypothalamus, the bed nucleus of stria terminalis and the medial amygdala.
Brain research. Molecular brain research 2002;106(1-2):30-41.
2002: Xin Yun Lu; Kun-Ruey Shieh; Mohamed Kabbaj; Gregory S Barsh; Huda Akil; Stanley J Watson Jr
Diurnal rhythm of agouti-related protein and its relation to corticosterone and food intake.
Endocrinology 2002;143(10):3905-15.
2002: Heidi E W Day; Nicole M Vittoz; Matthew M Oates; Aldo Badiani; Stanley J Watson Jr; Terry E Robinson; Huda Akil
A 6-hydroxydopamine lesion of the mesostriatal dopamine system decreases the expression of corticotropin releasing hormone and neurotensin mRNAs in the amygdala and bed nucleus of the stria terminalis.
Brain research 2002;945(2):151-9.
2002: Simon J Evans; Nicole A Datson; Mohamed Kabbaj; Robert C Thompson; Erno Vreugdenhil; Ron de Kloet; Stanley J Watson Jr; Huda Akil
Evaluation of Affymetrix Gene Chip sensitivity in rat hippocampal tissue using SAGE analysis. Serial Analysis of Gene Expression.
The European journal of neuroscience 2002;16(3):409-13.
2002: Serge Campeau; David F Dolan; Huda Akil; Stanley J Watson Jr
c-fos mRNA induction in acute and chronic audiogenic stress: possible role of the orbitofrontal cortex in habituation.
Stress (Amsterdam, Netherlands) 2002;5(2):121-30.
2002: Camille S Norton; Charles R Neal; Suneel Kumar; Huda Akil; Stanley J Watson Jr
Nociceptin/orphanin FQ and opioid receptor-like receptor mRNA expression in dopamine systems.
The Journal of comparative neurology 2002;444(4):358-68.
2002: Nakia S Gordon; Sara Kollack-Walker; Huda Akil; Jaak Panksepp
Expression of c-fos gene activation during rough and tumble play in juvenile rats.
Brain research bulletin 2002;57(5):651-9.
2002: Jennifer E Klebaur; Michelle M Ostrander; Camille S Norton; Stanley J Watson Jr; Huda Akil; Terry E Robinson
The ability of amphetamine to evoke arc (Arg 3.1) mRNA expression in the caudate, nucleus accumbens and neocortex is modulated by environmental context.
Brain research 2002;930(1-2):30-6.
2002: Constance E Owens; Huda Akil
Determinants of ligand selectivity at the kappa-receptor based on the structure of the orphanin FQ receptor.
The Journal of pharmacology and experimental therapeutics 2002;300(3):992-9.
2002: J R Nicholson; Huda Akil; Stanley J Watson Jr
Orphanin FQ-induced hyperphagia is mediated by corticosterone and central glucocorticoid receptors.
Neuroscience 2002;115(2):637-43.
2002: Mohamed Kabbaj; Ceylan Isgor; Stanley J Watson Jr; Huda Akil
Stress during adolescence alters behavioral sensitization to amphetamine.
Neuroscience 2002;113(2):395-400.
2002: Manuel O López-Figueroa; Claudio Alejandro Caamano; M Inés Morano; Huda Akil; Stanley J Watson Jr
Fluorescent imaging of mitochondrial nitric oxide in living cells.
Methods in enzymology 2002;352():296-303.
2002: Gavan P McNally; Huda Akil
Role of corticotropin-releasing hormone in the amygdala and bed nucleus of the stria terminalis in the behavioral, pain modulatory, and endocrine consequences of opiate withdrawal.
Neuroscience 2002;112(3):605-17.
2001: Mohamed Kabbaj; C S Norton; S Kollack-Walker; Stanley J Watson Jr; Terry E Robinson; Huda Akil
Social defeat alters the acquisition of cocaine self-administration in rats: role of individual differences in cocaine-taking behavior.
Psychopharmacology 2001;158(4):382-7.
2001: Jason M Uslaner; Aldo Badiani; Heidi E W Day; Stanley J Watson Jr; Huda Akil; Terry E Robinson
Environmental context modulates the ability of cocaine and amphetamine to induce c-fos mRNA expression in the neocortex, caudate nucleus, and nucleus accumbens.
Brain research 2001;920(1-2):106-16.
2001: Charles R Neal; Huda Akil; Stanley J Watson Jr
Expression of orphanin FQ and the opioid receptor-like (ORL1) receptor in the developing human and rat brain.
Journal of chemical neuroanatomy 2001;22(4):219-49.
2001: Manuel O López-Figueroa; Claudio Alejandro Caamano; R Marin; B Guerra; R Alonso; M Inés Morano; Huda Akil; Stanley J Watson Jr
Characterization of basal nitric oxide production in living cells.
Biochimica et biophysica acta 2001;1540(3):253-64.
2001: Gavan P McNally; Huda Akil
Effects of contextual or olfactory cues previously paired with morphine withdrawal on behavior and pain sensitivity in the rat.
Psychopharmacology 2001;156(4):381-7.
2001: Phillip B Danielson; M T Hoversten; M Fitzpatrick; C Schreck; Huda Akil; Robert M Dores
Sturgeon orphanin, a molecular "fossil" that bridges the gap between the opioids and orphanin FQ/nociceptin.
The Journal of biological chemistry 2001;276(25):22114-9.
2001: Xin Yun Lu; J R Nicholson; Huda Akil; Stanley J Watson Jr
Time course of short-term and long-term orexigenic effects of Agouti-related protein (86-132).
Neuroreport 2001;12(6):1281-4.
2001: Jason M Uslaner; Aldo Badiani; Camille S Norton; Heidi E W Day; Stanley J Watson Jr; Huda Akil; Terry E Robinson
Amphetamine and cocaine induce different patterns of c-fos mRNA expression in the striatum and subthalamic nucleus depending on environmental context.
The European journal of neuroscience 2001;13(10):1977-83.
2001: Dana L Helmreich; Keiichi Itoi; M O Lopez-Figueroa; Huda Akil; Stanley J Watson Jr
Norepinephrine-induced CRH and AVP gene transcription within the hypothalamus: differential regulation by corticosterone.
Brain research. Molecular brain research 2001;88(1-2):62-73.
2001: Heidi E W Day; Aldo Badiani; Jason M Uslaner; Matthew M Oates; N M Vittoz; Terry E Robinson; Stanley J Watson Jr; Huda Akil
Environmental novelty differentially affects c-fos mRNA expression induced by amphetamine or cocaine in subregions of the bed nucleus of the stria terminalis and amygdala.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(2):732-40.
2001: Claudio Alejandro Caamano; M Inés Morano; Huda Akil
Corticosteroid receptors: a dynamic interplay between protein folding and homeostatic control. Possible implications in psychiatric disorders.
Psychopharmacology bulletin 2001;35(1):6-23.
2001: Mohamed Kabbaj; Huda Akil
Individual differences in novelty-seeking behavior in rats: a c-fos study.
Neuroscience 2001;106(3):535-45.
2001: Darragh P Devine; Stanley J Watson Jr; Huda Akil
Nociceptin/orphanin FQ regulates neuroendocrine function of the limbic-hypothalamic-pituitary-adrenal axis.
Neuroscience 2001;102(3):541-53.
2000: Stanley J Watson Jr; Fan Meng; Robert C Thompson; Huda Akil
The "chip" as a specific genetic tool.
Biological psychiatry 2000;48(12):1147-56.
2000: Elizabeth A Young; Juan F Lopez; Virginia Murphy-Weinberg; Stanley J Watson Jr; Huda Akil
Hormonal evidence for altered responsiveness to social stress in major depression.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;23(4):411-8.
2000: Mohamed Kabbaj; D P Devine; V R Savage; Huda Akil
Neurobiological correlates of individual differences in novelty-seeking behavior in the rat: differential expression of stress-related molecules.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(18):6983-8.
2000: G Bonner; Fan Meng; Huda Akil
Selectivity of mu-opioid receptor determined by interfacial residues near third extracellular loop.
European journal of pharmacology 2000;403(1-2):37-44.
2000: Fan Meng; Qiang Wei; Mary T Hoversten; Larry P Taylor; Huda Akil
Switching agonist/antagonist properties of opiate alkaloids at the delta opioid receptor using mutations based on the structure of the orphanin FQ receptor.
The Journal of biological chemistry 2000;275(29):21939-45.
2000: Samuel P Lee; Brian F O'Dowd; Gordon Y K Ng; George Varghese; Huda Akil; A Mansour; Tuan V Nguyen; Susan R George
Inhibition of cell surface expression by mutant receptors demonstrates that D2 dopamine receptors exist as oligomers in the cell.
Molecular pharmacology 2000;58(1):120-8.
2000: Xin Yun Lu; D Bagnol; Sharon Burke; Huda Akil; Stanley J Watson Jr
Differential distribution and regulation of OX1 and OX2 orexin/hypocretin receptor messenger RNA in the brain upon fasting.
Hormones and behavior 2000;37(4):335-44.
2000: Manuel O López-Figueroa; Claudio Alejandro Caamano; M Inés Morano; L C Rønn; Huda Akil; Stanley J Watson Jr
Direct evidence of nitric oxide presence within mitochondria.
Biochemical and biophysical research communications 2000;272(1):129-33.
2000: Manuel O López-Figueroa; Heidi E W Day; S Lee; C Rivier; Huda Akil; Stanley J Watson Jr
Temporal and anatomical distribution of nitric oxide synthase mRNA expression and nitric oxide production during central nervous system inflammation.
Brain research 2000;852(1):239-46.
2000: Huda Akil; Stanley J Watson Jr
Science and the future of psychiatry.
Archives of general psychiatry 2000;57(1):86-7.
1999: Juan F Lopez; Huda Akil; Stanley J Watson Jr
Neural circuits mediating stress.
Biological psychiatry 1999;46(11):1461-71.
1999: Xin Yun Lu; T M Gunn; K r Shieh; G S Barsh; Huda Akil; Stanley J Watson Jr
Distribution of Mahogany/Attractin mRNA in the rat central nervous system.
FEBS letters 1999;462(1-2):101-7.
1999: Heidi E W Day; Serge Campeau; Stanley J Watson Jr; Huda Akil
Expression of alpha(1b) adrenoceptor mRNA in corticotropin-releasing hormone-containing cells of the rat hypothalamus and its regulation by corticosterone.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(22):10098-106.
1999: Heidi E W Day; E J Curran; Stanley J Watson Jr; Huda Akil
Distinct neurochemical populations in the rat central nucleus of the amygdala and bed nucleus of the stria terminalis: evidence for their selective activation by interleukin-1beta.
The Journal of comparative neurology 1999;413(1):113-28.
1999: Charles R Neal; A Mansour; Rainer K Reinscheid; Hans-Peter Nothacker; Olivier Civelli; Huda Akil; Stanley J Watson Jr
Opioid receptor-like (ORL1) receptor distribution in the rat central nervous system: comparison of ORL1 receptor mRNA expression with (125)I-[(14)Tyr]-orphanin FQ binding.
The Journal of comparative neurology 1999;412(4):563-605.
1999: Claire L Neilan; Huda Akil; James H Woods; John R Traynor
Constitutive activity of the delta-opioid receptor expressed in C6 glioma cells: identification of non-peptide delta-inverse agonists.
British journal of pharmacology 1999;128(3):556-62.
1999: D Bagnol; Xin Yun Lu; Christopher B Kaelin; Heidi E W Day; MM Ollmann; Ira Gantz; Huda Akil; Gregory S Barsh; Stanley J Watson Jr
Anatomy of an endogenous antagonist: relationship between Agouti-related protein and proopiomelanocortin in brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(18):RC26.
1999: Aldo Badiani; Matthew M Oates; Heidi E W Day; Stanley J Watson Jr; Huda Akil; Terry E Robinson
Environmental modulation of amphetamine-induced c-fos expression in D1 versus D2 striatal neurons.
Behavioural brain research 1999;103(2):203-9.
1999: K O Lee; Huda Akil; James H Woods; John R Traynor
Differential binding properties of oripavines at cloned mu- and delta-opioid receptors.
European journal of pharmacology 1999;378(3):323-30.
1999: Heidi E W Day; Huda Akil
Evidence that cholecystokinin receptors are not involved in the hypothalamic-pituitary-adrenal response to intraperitoneal administration of interleukin-1beta.
Journal of neuroendocrinology 1999;11(7):561-8.
1999: S Kollack-Walker; C Don; Stanley J Watson Jr; Huda Akil
Differential expression of c-fos mRNA within neurocircuits of male hamsters exposed to acute or chronic defeat.
Journal of neuroendocrinology 1999;11(7):547-59.
1999: Stanley J Watson Jr; Huda Akil
Gene chips and arrays revealed: a primer on their power and their uses.
Biological psychiatry 1999;45(5):533-43.
1999: Dana L Helmreich; L R Watkins; T Deak; S F Maier; Huda Akil; Stanley J Watson Jr
The effect of stressor controllability on stress-induced neuropeptide mRNA expression within the paraventricular nucleus of the hypothalamus.
Journal of neuroendocrinology 1999;11(2):121-8.
1999: Ann E Remmers; Mary J Clark; A Mansour; Huda Akil; James H Woods; F Medzihradsky
Opioid efficacy in a C6 glioma cell line stably expressing the human kappa opioid receptor.
The Journal of pharmacology and experimental therapeutics 1999;288(2):827-33.
1998: Aldo Badiani; Matthew M Oates; Heidi E W Day; Stanley J Watson Jr; Huda Akil; Terry E Robinson
Amphetamine-induced behavior, dopamine release, and c-fos mRNA expression: modulation by environmental novelty.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(24):10579-93.
1998: Manuel O López-Figueroa; Heidi E W Day; Huda Akil; Stanley J Watson Jr
Nitric oxide in the stress axis.
Histology and histopathology 1998;13(4):1243-52.
1998: Elizabeth A Young; Juan F Lopez; Virginia Murphy-Weinberg; Stanley J Watson Jr; Huda Akil
The role of mineralocorticoid receptors in hypothalamic-pituitary-adrenal axis regulation in humans.
The Journal of clinical endocrinology and metabolism 1998;83(9):3339-45.
1998: Claudio Alejandro Caamano; M Inés Morano; F C Dalman; William B Pratt; Huda Akil
A conserved proline in the hsp90 binding region of the glucocorticoid receptor is required for hsp90 heterocomplex stabilization and receptor signaling.
The Journal of biological chemistry 1998;273(32):20473-80.
1998: A Alt; A Mansour; Huda Akil; F Medzihradsky; John R Traynor; James H Woods
Stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding by endogenous opioids acting at a cloned mu receptor.
The Journal of pharmacology and experimental therapeutics 1998;286(1):282-8.
1998: Delia M Vázquez; Juan F Lopez; M Inés Morano; S P Kwak; Stanley J Watson Jr; Huda Akil
Alpha, beta, and gamma mineralocorticoid receptor messenger ribonucleic acid splice variants: differential expression and rapid regulation in the developing hippocampus.
Endocrinology 1998;139(7):3165-77.
1998: Huda Akil; C Owens; HB Gutstein; L Taylor; E Curran; Stanley J Watson Jr
Endogenous opioids: overview and current issues.
Drug and alcohol dependence 1998;51(1-2):127-40.
1998: HB Gutstein; A Mansour; Stanley J Watson Jr; Huda Akil; Howard Fields
Mu and kappa opioid receptors in periaqueductal gray and rostral ventromedial medulla.
Neuroreport 1998;9(8):1777-81.
1998: Fan Meng; Y Ueda; Mary T Hoversten; Larry P Taylor; Rainer K Reinscheid; FJ Monsma; Stanley J Watson Jr; Olivier Civelli; Huda Akil
Creating a functional opioid alkaloid binding site in the orphanin FQ receptor through site-directed mutagenesis.
Molecular pharmacology 1998;53(4):772-7.
1998: HB Gutstein; J L Thome; J L Fine; Stanley J Watson Jr; Huda Akil
Pattern of c-fos mRNA induction in rat brain by acute morphine.
Canadian journal of physiology and pharmacology 1998;76(3):294-303.
1998: Peter Coward; H G Wada; Matthew Falk; SD Chan; Fan Meng; Huda Akil; Bruce R Conklin
Controlling signaling with a specifically designed Gi-coupled receptor.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(1):352-7.
1997: PJ Emmerson; Steven Archer; W El-Hamouly; A Mansour; Huda Akil; F Medzihradsky
Synthesis and characterization of 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY)-labeled fluorescent ligands for the mu opioid receptor.
Biochemical pharmacology 1997;54(12):1315-22.
1997: Israel Liberzon; K A Trujillo; Huda Akil; Elizabeth A Young
Motivational properties of oxytocin in the conditioned place preference paradigm.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;17(6):353-9.
1997: S Kollack-Walker; Stanley J Watson Jr; Huda Akil
Social stress in hamsters: defeat activates specific neurocircuits within the brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(22):8842-55.
1997: HB Gutstein; EA Rubie; A Mansour; Huda Akil; James R Woodgett
Opioid effects on mitogen-activated protein kinase signaling cascades.
Anesthesiology 1997;87(5):1118-26.
1997: Mary J Clark; PJ Emmerson; A Mansour; Huda Akil; James H Woods; Philip S Portoghese; Ann E Remmers; F Medzihradsky
Opioid efficacy in a C6 glioma cell line stably expressing the delta opioid receptor.
The Journal of pharmacology and experimental therapeutics 1997;283(2):501-10.
1997: D Bagnol; A Mansour; Huda Akil; Stanley J Watson Jr
Cellular localization and distribution of the cloned mu and kappa opioid receptors in rat gastrointestinal tract.
Neuroscience 1997;81(2):579-91.
1997: Serge Campeau; Huda Akil; Stanley J Watson Jr
Lesions of the medial geniculate nuclei specifically block corticosterone release and induction of c-fos mRNA in the forebrain associated with audiogenic stress in rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(15):5979-92.
1997: Delia M Vázquez; M Inés Morano; L Taylor; Huda Akil
Kinetics of radiolabeled adrenocorticotropin hormone in infant and weanling rats.
Journal of neuroendocrinology 1997;9(7):529-36.
1997: Heidi E W Day; Serge Campeau; Stanley J Watson Jr; Huda Akil
Distribution of alpha 1a-, alpha 1b- and alpha 1d-adrenergic receptor mRNA in the rat brain and spinal cord.
Journal of chemical neuroanatomy 1997;13(2):115-39.
1997: B B Ruzicka; Huda Akil
The interleukin-1beta-mediated regulation of proenkephalin and opioid receptor messenger RNA in primary astrocyte-enriched cultures.
Neuroscience 1997;79(2):517-24.
1997: Elizabeth A Young; Juan F Lopez; Virginia Murphy-Weinberg; Stanley J Watson Jr; Huda Akil
Normal pituitary response to metyrapone in the morning in depressed patients: implications for circadian regulation of corticotropin-releasing hormone secretion.
Biological psychiatry 1997;41(12):1149-55.
1997: Joerns Fickel; D Bagnol; Stanley J Watson Jr; Huda Akil
Opioid receptor expression in the rat gastrointestinal tract: a quantitative study with comparison to the brain.
Brain research. Molecular brain research 1997;46(1-2):1-8.
1997: A Mansour; Larry P Taylor; J L Fine; Robert C Thompson; Mary T Hoversten; Henry I Mosberg; Stanley J Watson Jr; Huda Akil
Key residues defining the mu-opioid receptor binding pocket: a site-directed mutagenesis study.
Journal of neurochemistry 1997;68(1):344-53.
1996: Fan Meng; Larry P Taylor; Mary T Hoversten; Y Ueda; A Ardati; Rainer K Reinscheid; FJ Monsma; Stanley J Watson Jr; Olivier Civelli; Huda Akil
Moving from the orphanin FQ receptor to an opioid receptor using four point mutations.
The Journal of biological chemistry 1996;271(50):32016-20.
1996: E J Curran; Huda Akil; Stanley J Watson Jr
Psychomotor stimulant- and opiate-induced c-fos mRNA expression patterns in the rat forebrain: comparisons between acute drug treatment and a drug challenge in sensitized animals.
Neurochemical research 1996;21(11):1425-35.
1996: D P Devine; L Taylor; Rainer K Reinscheid; FJ Monsma; Olivier Civelli; Huda Akil
Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ.
Neurochemical research 1996;21(11):1387-96.
1996: Huda Akil
Special issue dedicated to Dr. Eric J. Simon.
Neurochemical research 1996;21(11):1271-5.
1996: W Cho; Larry P Taylor; Huda Akil
Mutagenesis of residues adjacent to transmembrane prolines alters D1 dopamine receptor binding and signal transduction.
Molecular pharmacology 1996;50(5):1338-45.
1996: Fan Meng; Y Ueda; Mary T Hoversten; Robert C Thompson; L Taylor; Stanley J Watson Jr; Huda Akil
Mapping the receptor domains critical for the binding selectivity of delta-opioid receptor ligands.
European journal of pharmacology 1996;311(2-3):285-92.
1996: P J Emmerson; Mary J Clark; A Mansour; Huda Akil; James H Woods; F Medzihradsky
Characterization of opioid agonist efficacy in a C6 glioma cell line expressing the mu opioid receptor.
The Journal of pharmacology and experimental therapeutics 1996;278(3):1121-7.
1996: Delia M Vázquez; H Van Oers; S Levine; Huda Akil
Regulation of glucocorticoid and mineralocorticoid receptor mRNAs in the hippocampus of the maternally deprived infant rat.
Brain research 1996;731(1-2):79-90.
1996: D P Devine; Rainer K Reinscheid; FJ Monsma; Olivier Civelli; Huda Akil
The novel neuropeptide orphanin FQ fails to produce conditioned place preference or aversion.
Brain research 1996;727(1-2):225-9.
1996: A Mansour; S Burke; R J Pavlic; Huda Akil; Stanley J Watson Jr
Immunohistochemical localization of the cloned kappa 1 receptor in the rat CNS and pituitary.
Neuroscience 1996;71(3):671-90.
1996: Heidi E W Day; Huda Akil
Differential pattern of c-fos mRNA in rat brain following central and systemic administration of interleukin-1-beta: implications for mechanism of action.
Neuroendocrinology 1996;63(3):207-18.
1996: B Watson; Fan Meng; Huda Akil
A chimeric analysis of the opioid receptor domains critical for the binding selectivity of mu opioid ligands.
Neurobiology of disease 1996;3(1):87-96.
1996: K Cucumel; I Garreau; J Mery; D Moinier; A Mansour; Huda Akil; Anny Cupo
Production and characterization of site-directed antibodies against dermorphin and dermorphin-related peptides.
Peptides 1996;17(6):973-82.
1996: Huda Akil; Fan Meng; A Mansour; Robert C Thompson; G X Xie; Stanley J Watson Jr
Cloning and characterization of multiple opioid receptors.
NIDA research monograph 1996;161():127-40.
1996: B B Ruzicka; Robert C Thompson; Stanley J Watson Jr; Huda Akil
Interleukin-1 beta-mediated regulation of mu-opioid receptor mRNA in primary astrocyte-enriched cultures.
Journal of neurochemistry 1996;66(1):425-8.
1995: B B Ruzicka; C A Fox; Robert C Thompson; Fan Meng; Stanley J Watson Jr; Huda Akil
Primary astroglial cultures derived from several rat brain regions differentially express mu, delta and kappa opioid receptor mRNA.
Brain research. Molecular brain research 1995;34(2):209-20.
1995: A Mansour; Mary T Hoversten; Larry P Taylor; Stanley J Watson Jr; Huda Akil
The cloned mu, delta and kappa receptors and their endogenous ligands: evidence for two opioid peptide recognition cores.
Brain research 1995;700(1-2):89-98.
1995: K A Trujillo; D M Bronstein; I O Sanchez; Huda Akil
Effects of chronic opiate and opioid antagonist treatment on striatal opioid peptides.
Brain research 1995;698(1-2):69-78.
1995: W Cho; Larry P Taylor; A Mansour; Huda Akil
Hydrophobic residues of the D2 dopamine receptor are important for binding and signal transduction.
Journal of neurochemistry 1995;65(5):2105-15.
1995: Claudio Alejandro Caamano; M Inés Morano; F C Dalman; Mary T Hoversten; Stanley J Watson Jr; William B Pratt; Huda Akil
Point mutations in the 90-kDa heat shock protein binding region of the glucocorticoid receptor affect the functional characteristics of the receptor.
Annals of the New York Academy of Sciences 1995;761():403-4.
1995: James P Herman; William E Cullinan; M I Morano; Huda Akil; Stanley J Watson Jr
Contribution of the ventral subiculum to inhibitory regulation of the hypothalamo-pituitary-adrenocortical axis.
Journal of neuroendocrinology 1995;7(6):475-82.
1995: Fan Meng; Mary T Hoversten; Robert C Thompson; L Taylor; Stanley J Watson Jr; Huda Akil
A chimeric study of the molecular basis of affinity and selectivity of the kappa and the delta opioid receptors. Potential role of extracellular domains.
The Journal of biological chemistry 1995;270(21):12730-6.
1995: HB Gutstein; K A Trujillo; Huda Akil
Does chronic nociceptive stimulation alter the development of morphine tolerance?
Brain research 1995;680(1-2):173-9.
1995: K A Trujillo; Huda Akil
Excitatory amino acids and drugs of abuse: a role for N-methyl-D-aspartate receptors in drug tolerance, sensitization and physical dependence.
Drug and alcohol dependence 1995;38(2):139-54.
1995: A Mansour; C A Fox; S Burke; Huda Akil; Stanley J Watson Jr
Immunohistochemical localization of the cloned mu opioid receptor in the rat CNS.
Journal of chemical neuroanatomy 1995;8(4):283-305.
1995: Elizabeth A Young; Huda Akil; R F Haskett; Stanley J Watson Jr
Evidence against changes in corticotroph CRF receptors in depressed patients.
Biological psychiatry 1995;37(6):355-63.
1995: Aldo Badiani; M Inés Morano; Huda Akil; Terry E Robinson
Circulating adrenal hormones are not necessary for the development of sensitization to the psychomotor activating effects of amphetamine.
Brain research 1995;673(1):13-24.
1995: B B Ruzicka; Huda Akil
Differential cellular regulation of pro-opiomelanocortin by interleukin-1-beta and corticotropin-releasing hormone.
Neuroendocrinology 1995;61(2):136-51.
1995: A Mansour; Stanley J Watson Jr; Huda Akil
Opioid receptors: past, present and future.
Trends in neurosciences 1995;18(2):69-70.
1995: W E Cullinan; J P Herman; Deborah F Battaglia; Huda Akil; Stanley J Watson Jr
Pattern and time course of immediate early gene expression in rat brain following acute stress.
Neuroscience 1995;64(2):477-505.
1995: A Mansour; C A Fox; Huda Akil; Stanley J Watson Jr
Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications.
Trends in neurosciences 1995;18(1):22-9.
1994: A Mansour; C A Fox; S Burke; Fan Meng; Robert C Thompson; Huda Akil; Stanley J Watson Jr
Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: an in situ hybridization study.
The Journal of comparative neurology 1994;350(3):412-38.
1994: Claudio Alejandro Caamano; M Inés Morano; Stanley J Watson Jr; F C Dalman; William B Pratt; Huda Akil
The functional relevance of the heteromeric structure of corticosteroid receptors.
Annals of the New York Academy of Sciences 1994;746():68-77; discussion 77-8, 131-3.
1994: Fan Meng; G X Xie; D Chalmers; Caurnel Morgan; Stanley J Watson Jr; Huda Akil
Cloning and characterization of a pharmacologically distinct A1 adenosine receptor from guinea pig brain.
Brain research. Molecular brain research 1994;26(1-2):143-55.
1994: M Inés Morano; Delia M Vázquez; Huda Akil
The role of the hippocampal mineralocorticoid and glucocorticoid receptors in the hypothalamo-pituitary-adrenal axis of the aged Fisher rat.
Molecular and cellular neurosciences 1994;5(5):400-12.
1994: Elizabeth A Young; R F Haskett; Leon Grunhaus; A Pande; V M Weinberg; Stanley J Watson Jr; Huda Akil
Increased evening activation of the hypothalamic-pituitary-adrenal axis in depressed patients.
Archives of general psychiatry 1994;51(9):701-7.
1994: Fan Meng; G X Xie; D Chalmers; Caurnel Morgan; Stanley J Watson Jr; Huda Akil
Cloning and expression of the A2a adenosine receptor from guinea pig brain.
Neurochemical research 1994;19(5):613-21.
1994: D T Chalmers; Juan F Lopez; Delia M Vázquez; Huda Akil; Stanley J Watson Jr
Regulation of hippocampal 5-HT1A receptor gene expression by dexamethasone.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1994;10(3):215-22.
1994: G X Xie; Fan Meng; A Mansour; Robert C Thompson; Mary T Hoversten; A Goldstein; Stanley J Watson Jr; Huda Akil
Primary structure and functional expression of a guinea pig kappa opioid (dynorphin) receptor.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):3779-83.
1994: A Mansour; C A Fox; Robert C Thompson; Huda Akil; Stanley J Watson Jr
mu-Opioid receptor mRNA expression in the rat CNS: comparison to mu-receptor binding.
Brain research 1994;643(1-2):245-65.
1994: A Mansour; C A Fox; Fan Meng; Huda Akil; Stanley J Watson Jr
Kappa 1 receptor mRNA distribution in the rat CNS: comparison to kappa receptor binding and prodynorphin mRNA.
Molecular and cellular neurosciences 1994;5(2):124-44.
1994: Juan F Lopez; D T Chalmers; Delia M Vázquez; Stanley J Watson Jr; Huda Akil
Serotonin transporter mRNA in rat brain is regulated by classical antidepressants.
Biological psychiatry 1994;35(4):287-90.
1994: K A Trujillo; Huda Akil
Inhibition of opiate tolerance by non-competitive N-methyl-D-aspartate receptor antagonists.
Brain research 1994;633(1-2):178-88.
1994: A Dupuy; Iris Lindberg; Y Zhou; Huda Akil; Claude Lazure; Michel Chrétien; Nabil G Seidah; R Day
Processing of prodynorphin by the prohormone convertase PC1 results in high molecular weight intermediate forms. Cleavage at a single arginine residue.
FEBS letters 1994;337(1):60-5.
1994: Huda Akil; Stanley J Watson Jr
Cloning of kappa opioid receptors: functional significance and future directions.
Progress in brain research 1994;100():81-6.
1993: Robert Day; M K Schäfer; M W Collard; E Weihe; Huda Akil
Prodynorphin gene expression in the rat intermediate pituitary lobe: gender differences and postpartum regulation.
Endocrinology 1993;133(6):2652-9.
1993: S P Kwak; Paresh D Patel; Robert C Thompson; Huda Akil; Stanley J Watson Jr
5'-Heterogeneity of the mineralocorticoid receptor messenger ribonucleic acid: differential expression and regulation of splice variants within the rat hippocampus.
Endocrinology 1993;133(5):2344-50.
1993: D M Vázquez; Huda Akil
Pituitary-adrenal response to ether vapor in the weanling animal: characterization of the inhibitory effect of glucocorticoids on adrenocorticotropin secretion.
Pediatric research 1993;34(5):646-53.
1993: Robert C Thompson; A Mansour; Huda Akil; Stanley J Watson Jr
Cloning and pharmacological characterization of a rat mu opioid receptor.
Neuron 1993;11(5):903-13.
1993: Fan Meng; G X Xie; Robert C Thompson; A Mansour; A Goldstein; Stanley J Watson Jr; Huda Akil
Cloning and pharmacological characterization of a rat kappa opioid receptor.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):9954-8.
1993: A Mansour; Robert C Thompson; Huda Akil; Stanley J Watson Jr
Delta opioid receptor mRNA distribution in the brain: comparison to delta receptor binding and proenkephalin mRNA.
Journal of chemical neuroanatomy 1993;6(6):351-62.
1993: Delia M Vázquez; M Inés Morano; Juan F Lopez; Stanley J Watson Jr; Huda Akil
Short-term adrenalectomy increases glucocorticoid and mineralocorticoid receptor mRNA in selective areas of the developing hippocampus.
Molecular and cellular neurosciences 1993;4(5):455-71.
1993: Elizabeth A Young; D Bronstein; Huda Akil
Dopamine regulation of swim stress induction of the pituitary intermediate lobe proopiomelanocortin system.
Neuroendocrinology 1993;58(3):294-302.
1993: Claudio Alejandro Caamano; M Inés Morano; Paresh D Patel; Stanley J Watson Jr; Huda Akil
A bacterially expressed mineralocorticoid receptor is associated in vitro with the 90-kilodalton heat shock protein and shows typical hormone- and DNA-binding characteristics.
Biochemistry 1993;32(33):8589-95.
1993: Hsia-lien Lin; N C Day; Y Ueda; D K Martin; J E Dixon; N G Seidah; Huda Akil
Tissue-specific and substrate-specific endoproteolytic cleavage of monkey pro-opiomelanocortin in heterologous endocrine cells: processing at Lys-Lys dibasic pairs.
Neuroendocrinology 1993;58(1):94-105.
1993: D M Bronstein; HB Gutstein; Huda Akil
Effects of chronic morphine treatment on beta-endorphin-related peptides in the caudal medulla and spinal cord.
Journal of neurochemistry 1993;60(6):2304-7.
1993: Elizabeth A Young; J Kotun; R F Haskett; Leon Grunhaus; John F Greden; Stanley J Watson Jr; Huda Akil
Dissociation between pituitary and adrenal suppression to dexamethasone in depression.
Archives of general psychiatry 1993;50(5):395-403.
1993: N C Day; H Lin; Y Ueda; James Meador-Woodruff; Huda Akil
Characterization of pro-opiomelanocortin processing in heterologous neuronal cells that express PC2 mRNA.
Neuropeptides 1993;24(5):253-62.
1993: D T Chalmers; S P Kwak; A Mansour; Huda Akil; Stanley J Watson Jr
Corticosteroids regulate brain hippocampal 5-HT1A receptor mRNA expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(3):914-23.
1993: Elizabeth A Young; R Przewlocki; Paresh D Patel; Stanley J Watson Jr; Huda Akil
Altered ratios of beta-endorphin: beta-lipotropin released from anterior lobe corticotropes with increased secretory drive. I. Effects of diminished glucocorticoid secretion.
Journal of neuroendocrinology 1993;5(1):115-20.
1993: Elizabeth A Young; R Day; M Schafer; Stanley J Watson Jr; Huda Akil
Altered ratios of beta-endorphin:beta-lipotropin released from anterior lobe corticotropes with increased secretory drive. II. Repeated stress.
Journal of neuroendocrinology 1993;5(1):121-6.
1993: Huda Akil; R F Haskett; Elizabeth A Young; Leon Grunhaus; J Kotun; V Weinberg; John F Greden; Stanley J Watson Jr
Multiple HPA profiles in endogenous depression: effect of age and sex on cortisol and beta-endorphin.
Biological psychiatry 1993;33(2):73-85.
1993: D M Bronstein; N C Day; HB Gutstein; K A Trujillo; Huda Akil
Pre- and posttranslational regulation of beta-endorphin biosynthesis in the CNS: effects of chronic naltrexone treatment.
Journal of neurochemistry 1993;60(1):40-9.
1993: S P Kwak; M Inés Morano; Elizabeth A Young; Stanley J Watson Jr; Huda Akil
Diurnal CRH mRNA rhythm in the hypothalamus: decreased expression in the evening is not dependent on endogenous glucocorticoids.
Neuroendocrinology 1993;57(1):96-105.
1992: HB Gutstein; D M Bronstein; Huda Akil
Beta-endorphin processing and cellular origins in rat spinal cord.
Pain 1992;51(2):241-7.
1992: James P Herman; William E Cullinan; E A Young; Huda Akil; Stanley J Watson Jr
Selective forebrain fiber tract lesions implicate ventral hippocampal structures in tonic regulation of paraventricular nucleus corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) mRNA expression.
Brain research 1992;592(1-2):228-38.
1992: A Mansour; Fan Meng; James Meador-Woodruff; Larry P Taylor; Olivier Civelli; Huda Akil
Site-directed mutagenesis of the human dopamine D2 receptor.
European journal of pharmacology 1992;227(2):205-14.
1992: Juan F Lopez; Miklós Palkovits; M Arató; A Mansour; Huda Akil; Stanley J Watson Jr
Localization and quantification of pro-opiomelanocortin mRNA and glucocorticoid receptor mRNA in pituitaries of suicide victims.
Neuroendocrinology 1992;56(4):491-501.
1992: Delia M Vázquez; Huda Akil
Development of pituitary pro-opiomelanocortin gene and peptide expression: characterization and effect of repeated intermittent maternal isolation.
Neuroendocrinology 1992;56(3):320-30.
1992: D M Bronstein; M K Schafer; Stanley J Watson Jr; Huda Akil
Evidence that beta-endorphin is synthesized in cells in the nucleus tractus solitarius: detection of POMC mRNA.
Brain research 1992;587(2):269-75.
1992: S P Kwak; Elizabeth A Young; Huda Akil; Stanley J Watson Jr
Changes in proopiomelanocortin primary transcript levels in the anterior pituitary accompany increased adrenocorticotropin secretion during the diurnal surge.
Journal of neuroendocrinology 1992;4(1):21-8.
1992: A Mansour; James Meador-Woodruff; Q Zhou; Olivier Civelli; Huda Akil; Stanley J Watson Jr
A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques.
Neuroscience 1992;46(4):959-71.
1992: S P Kwak; Elizabeth A Young; I Morano; Stanley J Watson Jr; Huda Akil
Diurnal corticotropin-releasing hormone mRNA variation in the hypothalamus exhibits a rhythm distinct from that of plasma corticosterone.
Neuroendocrinology 1992;55(1):74-83.
1991: James Meador-Woodruff; A Mansour; Daniel J Healy; R Kuehn; Q Y Zhou; James R Bunzow; Huda Akil; Olivier Civelli; Stanley J Watson Jr
Comparison of the distributions of D1 and D2 dopamine receptor mRNAs in rat brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1991;5(4):231-42.
1991: K A Trujillo; Huda Akil
Opiate tolerance and dependence: recent findings and synthesis.
The New biologist 1991;3(10):915-23.
1991: Elizabeth A Young; R F Haskett; Virginia Murphy-Weinberg; Stanley J Watson Jr; Huda Akil
Loss of glucocorticoid fast feedback in depression.
Archives of general psychiatry 1991;48(8):693-9.
1991: Elizabeth A Young; Leon Grunhaus; R F Haskett; A C Pande; Virginia Murphy-Weinberg; Huda Akil; Stanley J Watson Jr
Heterogeneity in the beta-endorphin immunoreactivity response to electroconvulsive therapy.
Archives of general psychiatry 1991;48(6):534-9.
1991: K A Trujillo; Huda Akil
The NMDA receptor antagonist MK-801 increases morphine catalepsy and lethality.
Pharmacology, biochemistry, and behavior 1991;38(3):673-5.
1991: F C Dalman; L C Scherrer; Larry P Taylor; Huda Akil; William B Pratt
Localization of the 90-kDa heat shock protein-binding site within the hormone-binding domain of the glucocorticoid receptor by peptide competition.
The Journal of biological chemistry 1991;266(6):3482-90.
1991: R Day; M K Schafer; Michael W Collard; Stanley J Watson Jr; Huda Akil
Atypical prodynorphin gene expression in corticosteroid-producing cells of the rat adrenal gland.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(4):1320-4.
1991: K A Trujillo; Huda Akil
Inhibition of morphine tolerance and dependence by the NMDA receptor antagonist MK-801.
Science (New York, N.Y.) 1991;251(4989):85-7.
1991: W E Cullinan; N C Day; M K Schäfer; R Day; N G Seidah; M Chrétien; Huda Akil; Stanley J Watson Jr
Neuroanatomical and functional studies of peptide precursor-processing enzymes.
Enzyme 1991;45(5-6):285-300.
1991: D M Bronstein; J E Kelsey; Huda Akil
Regulation of beta-endorphin biosynthesis in the brain: different effects of morphine pelleting and repeated stress.
NIDA research monograph 1991;111():113-32.
1991: A Mansour; James Meador-Woodruff; Q Y Zhou; Olivier Civelli; Huda Akil; Stanley J Watson Jr
A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques.
Neuroscience 1991;45(2):359-71.
1991: Charles Nemeroff; Garth Bissette; Huda Akil; M Fink
Neuropeptide concentrations in the cerebrospinal fluid of depressed patients treated with electroconvulsive therapy. Corticotrophin-releasing factor, beta-endorphin and somatostatin.
The British journal of psychiatry : the journal of mental science 1991;158():59-63.
1990: Michael W Collard; R Day; Huda Akil; Michael D Uhler; J O Douglass
Sertoli cells are the primary site of prodynorphin gene expression in rat testis: regulation of mRNA and secreted peptide levels by cyclic adenosine 3' ,5'-monophosphate analogs in cultured cells.
Molecular endocrinology (Baltimore, Md.) 1990;4(10):1488-96.
1990: A Mansour; James Meador-Woodruff; James R Bunzow; Olivier Civelli; Huda Akil; Stanley J Watson Jr
Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization-receptor autoradiographic analysis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(8):2587-600.
1990: D M Bronstein; R Przewlocki; Huda Akil
Effects of morphine treatment on pro-opiomelanocortin systems in rat brain.
Brain research 1990;519(1-2):102-11.
1990: K A Trujillo; R Day; Huda Akil
Regulation of striatonigral prodynorphin peptides by dopaminergic agents.
Brain research 1990;518(1-2):244-56.
1990: D M Bronstein; Huda Akil
In vitro release of hypothalamic beta-endorphin (beta E) by arginine vasopressin, corticotropin-releasing hormone and 5-hydroxytryptamine: evidence for release of opioid active and inactive beta E forms.
Neuropeptides 1990;16(1):33-40.
1990: Elizabeth A Young; Stanley J Watson Jr; J Kotun; R F Haskett; Leon Grunhaus; Virginia Murphy-Weinberg; W Vale; J Rivier; Huda Akil
Beta-lipotropin-beta-endorphin response to low-dose ovine corticotropin releasing factor in endogenous depression. Preliminary studies.
Archives of general psychiatry 1990;47(5):449-57.
1990: M K Schäfer; R Day; M R Ortega; Huda Akil; Stanley J Watson Jr
Proenkephalin messenger RNA is expressed both in the rat anterior and posterior pituitary.
Neuroendocrinology 1990;51(4):444-8.
1990: James Meador-Woodruff; B Pellerito; D Bronstein; Hsia-lien Lin; N Ling; Huda Akil
Differential effects of haloperidol on the rat pituitary: decreased biosynthesis, processing and release of anterior lobe pro-opiomelanocortin.
Neuroendocrinology 1990;51(3):294-303.
1990: M K Schafer; R Day; Huda Akil; Stanley J Watson Jr
Identification of prodynorphin and proenkephalin mRNA expressing cells in the neurointermediate lobe of the rat pituitary gland.
Progress in clinical and biological research 1990;328():231-4.
1990: K A Trujillo; Huda Akil
Pharmacological regulation of striatal prodynorphin peptides.
Progress in clinical and biological research 1990;328():223-6.
1990: D Bronstein; Huda Akil
Effects of electrical stimulation in the periaqueductal gray on POMC peptides and mRNA in the rat brain.
Progress in clinical and biological research 1990;328():219-22.
1990: A Mansour; James Meador-Woodruff; D M Camp; Terry E Robinson; James R Bunzow; Hubert H M Van Tol; Olivier Civelli; Huda Akil; Stanley J Watson Jr
The effects of nigrostriatal 6-hydroxydopamine lesions on dopamine D2 receptor mRNA and opioid systems.
Progress in clinical and biological research 1990;328():227-30.
1990: R Day; M K Schafer; Stanley J Watson Jr; Huda Akil
Effect of hypophysectomy on dynorphin mRNA and peptide content in the rat adrenal gland.
Progress in clinical and biological research 1990;328():207-10.
1990: K A Trujillo; Huda Akil
Opioid and non-opioid behavioral actions of dynorphin A and the dynorphin analogue DAKLI.
NIDA research monograph 1990;105():397-8.
1989: J P Herman; K H Schäfer; C D Sladek; R Day; Elizabeth A Young; Huda Akil; Stanley J Watson Jr
Chronic electroconvulsive shock treatment elicits up-regulation of CRF and AVP mRNA in select populations of neuroendocrine neurons.
Brain research 1989;501(2):235-46.
1989: J P Herman; Paresh D Patel; Huda Akil; Stanley J Watson Jr
Localization and regulation of glucocorticoid and mineralocorticoid receptor messenger RNAs in the hippocampal formation of the rat.
Molecular endocrinology (Baltimore, Md.) 1989;3(11):1886-94.
1989: J P Herman; M K Schäfer; Elizabeth A Young; Robert C Thompson; J Douglass; Huda Akil; Stanley J Watson Jr
Evidence for hippocampal regulation of neuroendocrine neurons of the hypothalamo-pituitary-adrenocortical axis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(9):3072-82.
1989: Elizabeth A Young; R A Houghten; Huda Akil
Degradation of [3H]beta-endorphin in rat plasma is increased with chronic stress.
European journal of pharmacology 1989;167(2):229-36.
1989: C D Minth; H Qiu; Huda Akil; Stanley J Watson Jr; J E Dixon
Two precursors of melanin-concentrating hormone: DNA sequence analysis and in situ immunochemical localization.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(11):4292-6.
1989: R Day; Huda Akil
The posttranslational processing of prodynorphin in the rat anterior pituitary.
Endocrinology 1989;124(5):2392-405.
1989: James Meador-Woodruff; Kenneth R Silk; Z Kronfol; Stanley J Watson Jr; Huda Akil
Gamma-melanotropin and beta-endorphin after dexamethasone.
Biological psychiatry 1989;25(7):975-6.
1989: K A Trujillo; Huda Akil
Changes in prodynorphin peptide content following treatment with morphine or amphetamine: possible role in mechanisms of action of drug of abuse.
NIDA research monograph 1989;95():550-1.
1988: T G Sherman; R Day; Olivier Civelli; J Douglass; E Herbert; Huda Akil; Stanley J Watson Jr
Regulation of hypothalamic magnocellular neuropeptides and their mRNAs in the Brattleboro rat: coordinate responses to further osmotic challenge.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(10):3785-96.
1988: Henry I Mosberg; R C Haaseth; K Ramalingam; A Mansour; Huda Akil; Ronald W Woodard
Role of steric interactions in the delta opioid receptor selectivity of [D-Pen2, D-Pen5]enkephalin.
International journal of peptide and protein research 1988;32(1):1-8.
1988: A Mansour; H Khachaturian; M E Lewis; Huda Akil; Stanley J Watson Jr
Anatomy of CNS opioid receptors.
Trends in neurosciences 1988;11(7):308-14.
1988: James Meador-Woodruff; B Pellerito; H Vaudry; S Jégou; N G Seidah; Stanley J Watson Jr; Huda Akil
Regional processing of the N- and C-terminal domains of proopiomelanocortin in monkey pituitary and brain.
Neuropeptides 1988;11(3):111-8.
1988: D Bronstein; K Trujillio; Huda Akil
Effects of morphine treatment on endogenous opioid biosynthesis.
NIDA research monograph 1988;90():256-65.
1988: Elizabeth A Young; Huda Akil
Paradoxical effect of corticosteroids on pituitary ACTH/beta-endorphin release in stressed animals.
Psychoneuroendocrinology 1988;13(4):317-23.
1988: Stanley J Watson Jr; Juan F Lopez; Elizabeth A Young; W Vale; J Rivier; Huda Akil
Effects of low dose ovine corticotropin-releasing hormone in humans: endocrine relationships and beta-endorphin/beta-lipotropin responses.
The Journal of clinical endocrinology and metabolism 1988;66(1):10-5.
1987: J W Lewis; G Baldrighi; Huda Akil
A possible interface between autonomic function and pain control: opioid analgesia and the nucleus tractus solitarius.
Brain research 1987;424(1):65-70.
1987: James Meador-Woodruff; R F Haskett; Leon Grunhaus; Huda Akil; Stanley J Watson Jr; John F Greden
Postdexamethasone plasma cortisol and beta-endorphin levels in depression: relationship to severity of illness.
Biological psychiatry 1987;22(9):1137-50.
1987: J Michael Walker; D H Coy; E A Young; G Baldrighi; S F Siegel; Wayne D Bowen; Huda Akil
[D-Ala2, (F5) Phe4]-dynorphin 1-13-NH2 (DAFPHEDYN): a potent analog of dynorphin 1-13.
Peptides 1987;8(5):811-7.
1987: A Mansour; H Khachaturian; M E Lewis; Huda Akil; Stanley J Watson Jr
Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(8):2445-64.
1987: Terry E Robinson; Jill B Becker; E A Young; Huda Akil; E Castaneda
The effects of footshock stress on regional brain dopamine metabolism and pituitary beta-endorphin release in rats previously sensitized to amphetamine.
Neuropharmacology 1987;26(7A):679-91.
1987: E A Young; J M Walker; R Houghten; Huda Akil
The degradation of dynorphin A in brain tissue in vivo and in vitro.
Peptides 1987;8(4):701-7.
1987: James Meador-Woodruff; Stanley J Watson Jr; V Murphy-Weinberg; S Jegou; H Vaudry; N G Seidah; J Rivier; W Vale; Huda Akil
Gamma-melanotropin response to ovine corticotropin releasing factor in normal humans.
Neuropeptides 1987;9(4):269-82.
1987: R M Dores; Huda Akil
Species-specific processing of prodynorphin in the posterior pituitary of mammals.
Endocrinology 1987;120(1):230-8.
1987: J Michael Walker; A Ghessari; B A Peters; Stanley J Watson Jr; Nabil G Seidah; M Chretien; Huda Akil
Functional aspects of multitransmitter neurons. Studies of interactions among pro-opiomelanocortin products.
Pain and headache 1987;9():160-77.
1987: J Lewis; A Mansour; H Khachaturian; Stanley J Watson Jr; Huda Akil
Opioids and pain regulation.
Pain and headache 1987;9():129-59.
1986: A Mansour; M E Lewis; H Khachaturian; Huda Akil; Stanley J Watson Jr
Pharmacological and anatomical evidence of selective mu, delta, and kappa opioid receptor binding in rat brain.
Brain research 1986;399(1):69-79.
1986: H Shiomi; Stanley J Watson Jr; J E Kelsey; Huda Akil
Pretranslational and posttranslational mechanisms for regulating beta-endorphin-adrenocorticotropin of the anterior pituitary lobe.
Endocrinology 1986;119(4):1793-9.
1986: David E Schteingart; R V Lloyd; Huda Akil; William F Chandler; G Ibarra-Perez; S G Rosen; R Ogletree
Cushing's syndrome secondary to ectopic corticotropin-releasing hormone-adrenocorticotropin secretion.
The Journal of clinical endocrinology and metabolism 1986;63(3):770-5.
1986: H Khachaturian; T G Sherman; R V Lloyd; Olivier Civelli; J Douglass; E Herbert; Huda Akil; Stanley J Watson Jr
Pro-dynorphin is endogenous to the anterior pituitary and is co-localized with LH and FSH in the gonadotrophs.
Endocrinology 1986;119(3):1409-11.
1986: M E Lewis; T G Sherman; S Burke; Huda Akil; L G Davis; R Arentzen; Stanley J Watson Jr
Detection of proopiomelanocortin mRNA by in situ hybridization with an oligonucleotide probe.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(15):5419-23.
1986: K Tsou; H Khachaturian; Huda Akil; Stanley J Watson Jr
Immunocytochemical localization of pro-opiomelanocortin-derived peptides in the adult rat spinal cord.
Brain research 1986;378(1):28-35.
1986: R M Dores; M Jain; Huda Akil
Characterization of the forms of beta-endorphin and alpha-MSH in the caudal medulla of the rat and guinea pig.
Brain research 1986;377(2):251-60.
1986: E A Young; J Lewis; Huda Akil
The preferential release of beta-endorphin from the anterior pituitary lobe by corticotropin releasing factor (CRF).
Peptides 1986;7(4):603-7.
1986: H Khachaturian; Huda Akil; M J Brownstein; J W Olney; K H Voigt; Stanley J Watson Jr
Further characterization of the extra-arcuate alpha-melanocyte stimulating hormone-like material in hypothalamus: biochemical and anatomical studies.
Neuropeptides 1986;7(3):291-313.
1986: J Matthews; Huda Akil; John F Greden; D Charney; V Weinberg; A Rosenbaum; Stanley J Watson Jr
beta-Endorphin/beta-lipotropin immunoreactivity in endogenous depression. Effect of dexamethasone.
Archives of general psychiatry 1986;43(4):374-81.
1986: E A Young; J M Walker; M E Lewis; R A Houghten; James H Woods; Huda Akil
[3H]dynorphin A binding and kappa selectivity of prodynorphin peptides in rat, guinea-pig and monkey brain.
European journal of pharmacology 1986;121(3):355-65.
1986: J E Kelsey; Stanley J Watson Jr; S Burke; Huda Akil; James Roberts
Characterization of proopiomelanocortin mRNA detected by in situ hybridization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1986;6(1):38-42.
1986: E A Young; Stanley J Watson Jr; Huda Akil
Pituitary regulation in endogenous depression.
Progress in brain research 1986;65():153-66.
1986: James Meador-Woodruff; M Knobloch; H Vaudry; N G Seidah; Stanley J Watson Jr; Huda Akil
Gamma-3-MSH and beta-endorphin in monkey pituitary.
NIDA research monograph 1986;75():307-10.
1986: Huda Akil; E Young; J M Walker; Stanley J Watson Jr
The many possible roles of opioids and related peptides in stress-induced analgesia.
Annals of the New York Academy of Sciences 1986;467():140-53.
1986: P A Berger; Stanley J Watson Jr; Huda Akil; J D Barchas
Investigating opioid peptides in schizophrenia and depression.
Research publications - Association for Research in Nervous and Mental Disease 1986;64():309-33.
1986: R Day; Huda Akil
Bridge peptide is a cleavage product of pro-dynorphin processing in the rat anterior pituitary.
NIDA research monograph 1986;75():244-6.
1986: A Mansour; M E Lewis; H Khachaturian; Huda Akil; Stanley J Watson Jr
Multiple opioid receptor subtypes in the pituitary-adrenal axis: a cross-species study.
NIDA research monograph 1986;75():311-4.
1986: L Taylor; A Mansour; Stanley J Watson Jr; Huda Akil
Anomalous binding of DPDPE as a result of batch variability.
NIDA research monograph 1986;75():201-4.
1986: C B Saper; Huda Akil; Stanley J Watson Jr
Lateral hypothalamic innervation of the cerebral cortex: immunoreactive staining for a peptide resembling but immunochemically distinct from pituitary/arcuate alpha-melanocyte stimulating hormone.
Brain research bulletin 1986;16(1):107-20.
1985: Huda Akil; D E Richardson
Contrast medium cause the apparent increase in beta-endorphin levels in human CSF following brain stimulation.
Pain 1985;23(3):301-4.
1985: E A Young; Huda Akil
Corticotropin-releasing factor stimulation of adrenocorticotropin and beta-endorphin release: effects of acute and chronic stress.
Endocrinology 1985;117(1):23-30.
1985: E Young; Huda Akil
Changes in releasability of ACTH and beta-endorphin with chronic stress.
Neuropeptides 1985;5(4-6):545-8.
1985: R M Dores; M E Lewis; H Khachaturian; Stanley J Watson Jr; Huda Akil
Analysis of opioid and non-opioid end products of pro-dynorphin in the substantia nigra of the rat.
Neuropeptides 1985;5(4-6):501-4.
1985: Huda Akil; H Shiomi; J Matthews
Induction of the intermediate pituitary by stress: synthesis and release of a nonopioid form of beta-endorphin.
Science (New York, N.Y.) 1985;227(4685):424-6.
1985: H Khachaturian; M E Lewis; S N Haber; R A Houghten; Huda Akil; Stanley J Watson Jr
Prodynorphin peptide immunocytochemistry in rhesus monkey brain.
Peptides 1985;6 Suppl 2():155-66.
1985: R M Dores; Huda Akil
Steady state levels of pro-dynorphin-related end products in the striatum and substantia nigra of the adult rhesus monkey.
Peptides 1985;6 Suppl 2():143-8.
1984: R M Dores; H Khachaturian; Stanley J Watson Jr; Huda Akil
Localization of neurons containing pro-opiomelanocortin-related peptides in the hypothalamus and midbrain of the lizard, Anolis carolinensis: evidence for region-specific processing of beta-endorphin.
Brain research 1984;324(2):384-9.
1984: M E Lewis; H Khachaturian; Huda Akil; Stanley J Watson Jr
Anatomical relationship between opioid peptides and receptors in rhesus monkey brain.
Brain research bulletin 1984;13(6):801-12.
1984: H Khachaturian; M E Lewis; S N Haber; Huda Akil; Stanley J Watson Jr
Proopiomelanocortin peptide immunocytochemistry in rhesus monkey brain.
Brain research bulletin 1984;13(6):785-800.
1984: J W Lewis; M E Lewis; D J Loomus; Huda Akil
Acute systemic administration of morphine selectively increases mu opioid receptor binding in the rat brain.
Neuropeptides 1984;5(1-3):117-20.
1984: H Khachaturian; R M Dores; Stanley J Watson Jr; Huda Akil
Beta-endorphin/ACTH immunocytochemistry in the CNS of the lizard Anolis carolinensis: evidence for a major mesencephalic cell group.
The Journal of comparative neurology 1984;229(4):576-84.
1984: M E Lewis; E A Young; R A Houghten; Huda Akil; Stanley J Watson Jr
Binding of [3H]dynorphin A to apparent kappa opioid receptors in deep layers of guinea pig cerebral cortex.
European journal of pharmacology 1984;98(1):149-50.
1984: Huda Akil; Stanley J Watson Jr; E Young; M E Lewis; H Khachaturian; J M Walker
Endogenous opioids: biology and function.
Annual review of neuroscience 1984;7():223-55.
1984: R M Dores; Huda Akil; Stanley J Watson Jr
Strategies for studying opioid peptide regulation at the gene, message and protein levels.
Peptides 1984;5 Suppl 1():9-17.
1983: E A Young; J M Walker; R Houghten; Huda Akil
[3H]Dynorphin A binds selectively to guinea pig brain.
European journal of pharmacology 1983;91(2-3):327-8.
1983: E Young; J Olney; Huda Akil
Selective alterations of opiate receptor subtypes in monosodium glutamate-treated rats.
Journal of neurochemistry 1983;40(6):1558-64.
1983: C A Cahill; J D Matthews; Huda Akil
Human plasma beta-endorphin-like peptides: a rapid, high recovery extraction technique and validation of radioimmunoassay.
The Journal of clinical endocrinology and metabolism 1983;56(5):992-7.
1983: Stanley J Watson Jr; H Khachaturian; L Taylor; W Fischli; A Goldstein; Huda Akil
Pro-dynorphin peptides are found in the same neurons throughout rat brain: immunocytochemical study.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(3):891-4.
1983: Huda Akil; H L Lin; Y Ueda; M Knobloch; Stanley J Watson Jr; D Coy
Some of the alpha-NH2-acetylated beta-endorphin-like material in rat and monkey pituitary and brain is acetylated alpha- and beta-endorphin.
Life sciences 1983;33 Suppl 1():9-12.
1983: C Cahill; Stanley J Watson Jr; M Knobloch; Huda Akil
POMC in rhesus anterior pituitary and plasma: evidence of N-acetylated beta-endorphin and alpha-MSH.
Life sciences 1983;33 Suppl 1():53-5.
1983: Norman Alessi; H Khachaturian; Stanley J Watson Jr; Huda Akil
Postnatal ontogeny of acetylated and non-acetylated B-endorphin in rat pituitary.
Life sciences 1983;33 Suppl 1():57-60.
1983: E Young; J M Walker; R Houghten; Huda Akil
[3H] dynorphin binding to guinea pig and rat brain.
Life sciences 1983;33 Suppl 1():287-90.
1982: J M Walker; H C Moises; D H Coy; G Baldrighi; Huda Akil
Nonopiate effects of dynorphin and des-Tyr-dynorphin.
Science (New York, N.Y.) 1982;218(4577):1136-8.
1982: Stanley J Watson Jr; H Khachaturian; Huda Akil; D H Coy; A Goldstein
Comparison of the distribution of dynorphin systems and enkephalin systems in brain.
Science (New York, N.Y.) 1982;218(4577):1134-6.
1982: H Shiomi; Huda Akil
Pulse-chase studies of the POMC/beta-endorphin system in the pituitary of acutely and chronically stressed rats.
Life sciences 1982;31(20-21):2185-8.
1982: Huda Akil; H Shiomi; Robert C Thompson; S Lax; D Coy; Stanley J Watson Jr
The signal peptide of pro-opiomelancortin: validation of a specific radioimmunoassay.
Life sciences 1982;31(20-21):2271-3.
1982: J M Walker; D E Tucker; D H Coy; B B Walker; Huda Akil
Des-tyrosine-dynorphin antagonizes morphine analgesia.
European journal of pharmacology 1982;85(1):121-2.
1982: H Khachaturian; Stanley J Watson Jr; M E Lewis; D Coy; A Goldstein; Huda Akil
Dynorphin immunocytochemistry in the rat central nervous system.
Peptides 1982;3(6):941-54.
1982: Norman Alessi; L Taylor; Huda Akil
Peptide F (pro-enkephalin fragment): radioimmunoassay, and stress-induced changes in adrenal.
Life sciences 1982;31(16-17):1875-8.
1982: C Cahill; Huda Akil
Plasma beta-endorphin-like immunoreactivity, self reported pain perception and anxiety levels in women during pregnancy and labor.
Life sciences 1982;31(16-17):1871-3.
1982: J Matthews; Huda Akil; John F Greden; Stanley J Watson Jr
Plasma measures of B-endorphin-like immunoreactivity in depressives and other psychiatric subjects.
Life sciences 1982;31(16-17):1867-70.
1982: J M Walker; H C Moises; D H Coy; E A Young; Stanley J Watson Jr; Huda Akil
Dynorphin (1-17): lack of analgesia but evidence for non-opiate electrophysiological and motor effects.
Life sciences 1982;31(16-17):1821-4.
1982: Stanley J Watson Jr; H Khachaturian; D Coy; L Taylor; Huda Akil
Dynorphin is located throughout the CNS and is often co-localized with alpha-neo-endorphin.
Life sciences 1982;31(16-17):1773-6.
1982: E Young; J Olney; Huda Akil
Increase in delta, but not mu, receptors in MSG-treated rats.
Life sciences 1982;31(12-13):1343-6.
1982: W A Hewlett; Huda Akil; W Carlini; J D Barchas
Tritiated ethylketocyclazocine binding in rat brain: differential distribution of binding sites across brain regions.
Life sciences 1982;31(12-13):1351-4.
1982: Stanley J Watson Jr; Huda Akil; W Fischli; A Goldstein; E Zimmerman; G Nilaver; T B van wimersma Griedanus
Dynorphin and vasopressin: common localization in magnocellular neurons.
Science (New York, N.Y.) 1982;216(4541):85-7.
1982: Huda Akil; H Shiomi; J M Walker; Stanley J Watson Jr
Characterization of multiple forms of beta-E in pituitary and brain: effect of stress.
Advances in biochemical psychopharmacology 1982;33():61-7.
1982: P A Berger; Huda Akil; Stanley J Watson Jr; J D Barchas
Behavioral pharmacology of the endorphins.
Annual review of medicine 1982;33():397-415.
1982: Stanley J Watson Jr; Huda Akil
Recent studies on dynorphin and enkephalin precursor fragments in central nervous system.
Advances in biochemical psychopharmacology 1982;33():35-42.
1981: P A Berger; Stanley J Watson Jr; Huda Akil; J D Barchas
The effects of naloxone in chronic schizophrenia.
The American journal of psychiatry 1981;138(7):913-8.
1981: Stanley J Watson Jr; Huda Akil; V E Ghazarossian; A Goldstein
Dynorphin immunocytochemical localization in brain and peripheral nervous system: preliminary studies.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(2):1260-3.
1981: J M Walker; G G Berntson; C A Sandman; A J Kastin; Huda Akil
Induction of analgesia by central administration of ORG 2766, an analog of ACTH4--9.
European journal of pharmacology 1981;69(1):71-9.
1981: P A Berger; Stanley J Watson Jr; Huda Akil; J D Barchas
Clinical studies on the role of endorphins in schizophrenia.
Modern problems of pharmacopsychiatry 1981;17():226-35.
1981: Huda Akil; E Young; Stanley J Watson Jr; D H Coy
Opiate binding properties of naturally occurring N- and C-terminus modified beta-endorphins.
Peptides 1981;2(3):289-92.
1981: Stanley J Watson Jr; Huda Akil
Opioid peptides and related substances: immunocytochemistry.
Advances in biochemical psychopharmacology 1981;28():77-86.
1980: J M Walker; Huda Akil; Stanley J Watson Jr
Evidence for homologous actions of pro-opiocortin products.
Science (New York, N.Y.) 1980;210(4475):1247-9.
1980: P A Berger; Stanley J Watson Jr; Huda Akil; G R Elliott; R T Rubin; A Pfefferbaum; Kenneth L Davis; J D Barchas; C H Li
beta-Endorphin and schizophrenia.
Archives of general psychiatry 1980;37(6):635-40.
1980: Huda Akil; W A Hewlett; J D Barchas; C H Li
Binding of 3H-beta-endorphin to rat brain membranes: characterization of opiate properties and interaction with ACTH.
European journal of pharmacology 1980;64(1):1-8.
1980: Stanley J Watson Jr; Huda Akil
alpha-MSH in rat brain: occurrence within and outside of beta-endorphin neurons.
Brain research 1980;182(1):217-23.
1980: J D Barchas; P A Berger; Stanley J Watson Jr; Huda Akil; C H Li
Opioid agonists and antagonists in schizophrenia.
Advances in biochemical psychopharmacology 1980;22():447-53.
1980: J M Walker; R J Katz; Huda Akil
Behavioral effects of dynorphin 1-13 in the mouse and rat: initial observations.
Peptides 1980;1(4):341-5.
1980: S Sullivan; Huda Akil; D Blacker; J D Barchas
Enkephalinase: selective inhibitors and partial characterization.
Peptides 1980;1(1):31-5.
1980: Huda Akil; Stanley J Watson Jr
Neuromodulatory functions of the brain pro-opiocortin system.
Advances in biochemical psychopharmacology 1980;22():435-45.
1979: Stanley J Watson Jr; Huda Akil
The presence of two alpha-MSH positive cell groups in rat hypothalamus.
European journal of pharmacology 1979;58(1):101-3.
1979: P A Berger; Stanley J Watson Jr; Huda Akil; J D Barchas
Prospects for the evaluation of endorphins as psychotropic agents.
Psychopharmacology bulletin 1979;15(3):33-5.
1979: Huda Akil; Stanley J Watson Jr; J D Barchas; C H Li
B-ETA-Endorphin immunoreactivity in rat and human blood: radioimmunoassay, comparative levels and physiological alterations.
Life sciences 1979;24(18):1659-65.
1979: Stanley J Watson Jr; Huda Akil; P A Berger; J D Barchas
Some observations on the opiate peptides and schizophrenia.
Archives of general psychiatry 1979;36(1):35-41.
1978: Huda Akil; D E Richardson; J D Barchas; C H Li
Appearance of beta-endorphin-like immunoreactivity in human ventricular cerebrospinal fluid upon analgesic electrical stimulation.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(10):5170-2.
1978: Stanley J Watson Jr; Huda Akil; C W Richard; J D Barchas
Evidence for two separate opiate peptide neuronal systems.
Nature 1978;275(5677):226-8.
1978: Huda Akil; D E Richardson; J Hughes; J D Barchas
Enkephalin-like material elevated in ventricular cerebrospinal fluid of pain patients after analgetic focal stimulation.
Science (New York, N.Y.) 1978;201(4354):463-5.
1978: Huda Akil; Stanley J Watson Jr; S Sullivan; J D Barchas
Enkephalin-like material in normal human CSF: measurement and levels.
Life sciences 1978;23(2):121-5.
1978: Stanley J Watson Jr; P A Berger; Huda Akil; M J Mills; J D Barchas
Effects of naloxone on schizophrenia: reduction in hallucinations in a subpopulation of subjects.
Science (New York, N.Y.) 1978;201(4350):73-6.
1978: J D Barchas; Huda Akil; G R Elliott; R B Holman; Stanley J Watson Jr
Behavioral neurochemistry: neuroregulators and behavioral states.
Science (New York, N.Y.) 1978;200(4344):964-73.
1978: Huda Akil; Stanley J Watson Jr; P A Berger; J D Barchas
Endorphins, beta-LPH, and ACTH: biochemical, pharmacological and anatomical studies.
Advances in biochemical psychopharmacology 1978;18():125-39.
1978: S Sullivan; Huda Akil; J D Barchas
In vitro degradation of enkephalin: evidence for cleavage at the Gly-Phe bond.
Communications in psychopharmacology 1978;2(6):525-31.
1977: Stanley J Watson Jr; Huda Akil; S Sullivan; J D Barchas
Immunocytochemical localization of methionine enkephalin: preliminary observations.
Life sciences 1977;21(5):733-8.
1977: D E Richardson; Huda Akil
Long term results of periventricular gray self-stimulation.
Neurosurgery 1977;1(2):199-202.
1977: D E Richardson; Huda Akil
Pain reduction by electrical brain stimulation in man. Part 1: Acute administration in periaqueductal and periventricular sites.
Journal of neurosurgery 1977;47(2):178-83.
1977: D E Richardson; Huda Akil
Pain reduction by electrical brain stimulation in man. Part 2: Chronic self-administration in the periventricular gray matter.
Journal of neurosurgery 1977;47(2):184-94.
1977: Stanley J Watson Jr; Huda Akil; J D Barchas
A possible role for the dorsal periventricular catecholamine bundle in stimulation produced analgesia: a behavioral and histochemical study.
Brain research 1977;130(2):335-42.
1977: J Madden; Huda Akil; R L Patrick; J D Barchas
Stress-induced parallel changes in central opioid levels and pain responsiveness in the rat.
Nature 1977;265(5592):358-60.
1977: S Sullivan; Huda Akil; Stanley J Watson Jr; J D Barchas
Antibodies to enkephalins: coupling of antigens and a specific methionine-enkephalin radioimmunoassay.
Communications in psychopharmacology 1977;1(6):605-10.
1976: Huda Akil; D J Mayer; J C Liebeskind
Antagonism of stimulation-produced analgesia by naloxone, a narcotic antagonist.
Science (New York, N.Y.) 1976;191(4230):961-2.
1975: Huda Akil; J C Liebeskind
Monoaminergic mechanisms of stimulation-produced analgesia.
Brain research 1975;94(2):279-96.
1972: Huda Akil; D J Mayer; J C Liebeskind
[Monoaminergic mechanisms involved in analgesia caused by stimulation of the brain stem in rats].
Journal de physiologie 1972;65():Suppl:185A.
1972: Huda Akil; D J Mayer
Antagonism of stimulation-produced analgesia by p-CPA, a serotonin synthesis inhibitor.
Brain research 1972;44(2):692-7.
1972: Huda Akil; D J Mayer; J C Liebeskind
[Comparison in the rat between analgesia induced by stimulation of periacqueducal gray matter and morphine analgesia].
Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D: Sciences naturelles 1972;274(26):3603-5.
1971: D J Mayer; T L Wolfle; Huda Akil; B Carder; J C Liebeskind
Analgesia from electrical stimulation in the brainstem of the rat.
Science (New York, N.Y.) 1971;174(4016):1351-4.