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Frank Porreca
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81
Lai, Josephine
68
Ossipov, Michael
57
Vanderah, Todd
54
Hruby, Victor
42
Davis, Peg
36
Malan, Philip
31
Yamamura, Henry
20
Ma, Shou-wu
20
Gardell, Luis
17
King, Tamara
12
Bian, Di
11
Lee, Yeon Sun
10
Mata, Heriberto
10
Agnes, Richard
10
Ibrahim, Mohab
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All Publications
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2009: De Felice M; Porreca F
Opiate-induced persistent pronociceptive trigeminal neural adaptations: potential relevance to opiate-induced medication overuse headache.
Cephalalgia : an international journal of headache 2009;29(12):1277-84.
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2009: King Tamara; Vera-Portocarrero Louis; Gutierrez Tannia; Vanderah Todd W; Dussor Gregory; Lai Josephine; Fields Howard L; Porreca Frank
Unmasking the tonic-aversive state in neuropathic pain.
Nature neuroscience 2009;12(11):1364-6.
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2009: Yamamoto Takashi; Nair Padma; Ma Shou-wu; Davis Peg; Yamamura Henry I; Vanderah Todd W; Porreca Frank; Lai Josephine; Hruby Victor J
The biological activity and metabolic stability of peptidic bifunctional compounds that are opioid receptor agonists and neurokinin-1 receptor antagonists with a cystine moiety.
Bioorganic & medicinal chemistry 2009;17(20):7337-43.
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2009: Roberts Jill; Ossipov Michael H; Porreca Frank
Glial activation in the rostroventromedial medulla promotes descending facilitation to mediate inflammatory hypersensitivity.
The European journal of neuroscience 2009;30(2):229-41.
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2009: Vardanyan Ruben; Vijay Gokhale; Nichol Gary S; Liu Lu; Kumarasinghe Isuru; Davis Peg; Vanderah Todd; Porreca Frank; Lai Josephine; Hruby Victor J
Synthesis and investigations of double-pharmacophore ligands for treatment of chronic and neuropathic pain.
Bioorganic & medicinal chemistry 2009;17(14):5044-53.
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2009: Porreca Frank; Ossipov Michael H
Nausea and vomiting side effects with opioid analgesics during treatment of chronic pain: mechanisms, implications, and management options.
Pain medicine (Malden, Mass.) 2009;10(4):654-62.
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2009: Porreca Frank; Vanderah Todd W
Spring pain research conference 2008.
Brain research reviews 2009;60(1):1.
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2009: Zhang Wenjun; Gardell Shannon; Zhang Dongqin; Xie Jennifer Y; Agnes Richard S; Badghisi Hamid; Hruby Victor J; Rance Naomi; Ossipov Michael H; Vanderah Todd W; Porreca Frank; Lai Josephine
Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors.
Brain : a journal of neurology 2009;132(Pt 3):778-87.
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2009: Vardanyan Anna; Wang Ruizhong; Vanderah Todd W; Ossipov Michael H; Lai Josephine; Porreca Frank; King Tamara
TRPV1 receptor in expression of opioid-induced hyperalgesia.
The journal of pain : official journal of the American Pain Society 2009;10(3):243-52.
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2009: Edelmayer Rebecca M; Vanderah Todd W; Majuta Lisa; Zhang En-Tan; Fioravanti Beatriz; De Felice Milena; Chichorro Juliana G; Ossipov Michael H; King Tamara; Lai Josephine; Kori Shashi H; Nelsen Andrew C; Cannon Keri E; Heinricher Mary M; Porreca Frank
Medullary pain facilitating neurons mediate allodynia in headache-related pain.
Annals of neurology 2009;65(2):184-93.
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2009: Rivat Cyril; Vera-Portocarrero Louis P; Ibrahim Mohab M; Mata Heriberto P; Stagg Nicola J; De Felice Milena; Porreca Frank; Malan T P
Spinal NK-1 receptor-expressing neurons and descending pathways support fentanyl-induced pain hypersensitivity in a rat model of postoperative pain.
The European journal of neuroscience 2009;29(4):727-37.
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2009: Nair Padma; Yamamoto Takashi; Kulkarni Vinod; Moye Sharif; Navratilova Edita; Davis Peg; Largent Tally; Ma Shou-Wu; Yamamura Henry I; Vanderah Todd; Lai Josephine; Porreca Frank; Hruby Victor J
Novel bifunctional peptides as opioid agonists and NK-1 antagonists.
Advances in experimental medicine and biology 2009;611():537-8.
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2009: Lee YeonSun; Petrov Ravil; Kulkarni Vinod; Min Byoung J; Ma Shou-Wu; Davis Peg; Oyarzo Janice; Vanderah Todd; Lai Josephine; Porreca Frank; Vardanyan Ruben; Hruby Victor J
Development of mu/delta opioid ligands: enkephalin analogues containing 4-anilidopiperidine moiety.
Advances in experimental medicine and biology 2009;611():517-8.
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2009: Kulkarni Vinod V; Lee Yeon Sun; Salibay Christine; Davis Peg; Ma Shou-Wu; Porreca Frank; Hruby Victor J
Novel analogues of bifunctional ligands for opioid and melanocortin 4 receptor.
Advances in experimental medicine and biology 2009;611():195-6.
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2008: Luo Miaw-Chyi; Chen Qingmin; Ossipov Michael H; Rankin David R; Porreca Frank; Lai Josephine
Spinal dynorphin and bradykinin receptors maintain inflammatory hyperalgesia.
The journal of pain : official journal of the American Pain Society 2008;9(12):1096-105.
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2008: Fioravanti Beatriz; De Felice Milena; Stucky Cheryl L; Medler Karen A; Luo Miaw-Chyi; Gardell Luis R; Ibrahim Mohab; Malan T Phil; Yamamura Henry I; Ossipov Michael H; King Tamara; Lai Josephine; Porreca Frank; Vanderah Todd W
Constitutive activity at the cannabinoid CB1 receptor is required for behavioral response to noxious chemical stimulation of TRPV1: antinociceptive actions of CB1 inverse agonists.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(45):11593-602.
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2008: Yamamoto Takashi; Nair Padma; Jacobsen Neil E; Davis Peg; Ma Shou-wu; Navratilova Edita; Moye Sharif; Lai Josephine; Yamamura Henry I; Vanderah Todd W; Porreca Frank; Hruby Victor J
The importance of micelle-bound states for the bioactivities of bifunctional peptide derivatives for delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists.
Journal of medicinal chemistry 2008;51(20):6334-47.
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2008: Vera-Portocarrero Louis P; Ossipov Michael H; King Tamara; Porreca Frank
Reversal of inflammatory and noninflammatory visceral pain by central or peripheral actions of sumatriptan.
Gastroenterology 2008;135(4):1369-78.
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2008: Agnes Richard S; Ying Jinfa; Kövér Katalin E; Lee Yeon Sun; Davis Peg; Ma Shou-wu; Badghisi Hamid; Porreca Frank; Lai Josephine; Hruby Victor J
Structure-activity relationships of bifunctional cyclic disulfide peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors.
Peptides 2008;29(8):1413-23.
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2008: Lai Josephine; Luo Miaw-chyi; Chen Qingmin; Porreca Frank
Pronociceptive actions of dynorphin via bradykinin receptors.
Neuroscience letters 2008;437(3):175-9.
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2008: Wang Ruizhong; King Tamara; Ossipov Michael H; Rossomando Anthony J; Vanderah Todd W; Harvey Pamela; Cariani Peter; Frank Eric; Sah Dinah W Y; Porreca Frank
Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury.
Nature neuroscience 2008;11(4):488-96.
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2008: Vanderah Todd W; Largent-Milnes Tally; Lai Josephine; Porreca Frank; Houghten Richard A; Menzaghi Frédérique; Wisniewski Kazimierz; Stalewski Jacek; Sueiras-Diaz Javier; Galyean Robert; Schteingart Claudio; Junien Jean-Louis; Trojnar Jerzy; Rivière Pierre J-M
Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptors.
European journal of pharmacology 2008;583(1):62-72.
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2008: Yamamoto Takashi; Nair Padma; Vagner Josef; Largent-Milnes Tally; Davis Peg; Ma Shou-Wu; Navratilova Edita; Moye Sharif; Tumati Suneeta; Lai Josephine; Yamamura Henry I; Vanderah Todd W; Porreca Frank; Hruby Victor J
A structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists.
Journal of medicinal chemistry 2008;51(5):1369-76.
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2008: King Tamara E; Pawar Sangita C; Majuta Lisa; Sroka Isis C; Wynn Danyel; Demetriou Manolis C; Nagle Raymond B; Porreca Frank; Cress Anne E
The role of alpha 6 integrin in prostate cancer migration and bone pain in a novel xenograft model.
PloS one 2008;3(10):e3535.
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2008: Lee Yeon Sun; Agnes Richard S; Cain James P; Kulkarni Vinod; Cai Minying; Salibay Christine; Ciano Kathy; Petrov Ravil; Mayorov Alexander; Vagner Josef; Trivedi Dev; Davis Peg; Ma Shou-wu; Lai Josephine; Porreca Frank; Vardanyan Ruben; Hruby Victor J
Opioid and melanocortin receptors: do they have overlapping pharmacophores?
Biopolymers 2008;90(3):433-8.
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2007: Lee Yeon Sun; Petrov Ravil; Park Chad K; Ma Shou-wu; Davis Peg; Lai Josephine; Porreca Frank; Vardanyan Ruben; Hruby Victor J
Development of novel enkephalin analogues that have enhanced opioid activities at both mu and delta opioid receptors.
Journal of medicinal chemistry 2007;50(22):5528-32.
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2007: King Tamara; Vardanyan Anna; Majuta Lisa; Melemedjian Ohannes; Nagle Ray; Cress Anne E; Vanderah Todd W; Lai Josephine; Porreca Frank
Morphine treatment accelerates sarcoma-induced bone pain, bone loss, and spontaneous fracture in a murine model of bone cancer.
Pain 2007;132(1-2):154-68.
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2007: Ossipov Michael H; Bazov Igor; Gardell Luis R; Kowal Justin; Yakovleva Tatiana; Usynin Ivan; Ekström Tomas J; Porreca Frank; Bakalkin Georgy
Control of chronic pain by the ubiquitin proteasome system in the spinal cord.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(31):8226-37.
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2007: Mollica Adriano; Guardiani Giovanni; Davis Peg; Ma Shou-Wu; Porreca Frank; Lai Josephine; Mannina Luisa; Sobolev Anatoli P; Hruby Victor J
Synthesis of stable and potent delta/mu opioid peptides: analogues of H-Tyr-c[D-Cys-Gly-Phe-D-Cys]-OH by ring-closing metathesis.
Journal of medicinal chemistry 2007;50(13):3138-42.
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2007: Yamamoto Takashi; Nair Padma; Davis Peg; Ma Shou-wu; Navratilova Edita; Moye Sharif; Tumati Suneeta; Lai Josephine; Vanderah Todd W; Yamamura Henry I; Porreca Frank; Hruby Victor J
Design, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for delta/mu opioid receptor agonists and neurokinin-1 receptor antagonists.
Journal of medicinal chemistry 2007;50(12):2779-86.
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2007: Zhang En-Tan; Ossipov Michael H; Zhang Dong-Qin; Lai Josephine; Porreca Frank
Nerve injury-induced tactile allodynia is present in the absence of FOS labeling in retrogradely labeled post-synaptic dorsal column neurons.
Pain 2007;129(1-2):143-54.
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2007: Vera-Portocarrero Louis P; Zhang En-Tan; King Tamara; Ossipov Michael H; Vanderah Todd W; Lai Josephine; Porreca Frank
Spinal NK-1 receptor expressing neurons mediate opioid-induced hyperalgesia and antinociceptive tolerance via activation of descending pathways.
Pain 2007;129(1-2):35-45.
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2007: Dogrul Ahmet; Gülmez S Ezgi; Deveci M Salih; Gul Husamettin; Ossipov Michael H; Porreca Frank; Tulunay F Cankat
The local antinociceptive actions of nonsteroidal antiinflammatory drugs in the mouse radiant heat tail-flick test.
Anesthesia and analgesia 2007;104(4):927-35.
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2007: Lee Yeon Sun; Nyberg Joel; Moye Sharif; Agnes Richard S; Davis Peg; Ma Shou-wu; Lai Josephine; Porreca Frank; Vardanyan Ruben; Hruby Victor J
Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at mu and delta opioid receptors.
Bioorganic & medicinal chemistry letters 2007;17(8):2161-5.
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2007: Lowery John J; Yeomans Larisa; Keyari Charles M; Davis Peg; Porreca Frank; Knapp Brian I; Bidlack Jean M; Bilsky Edward J; Polt Robin
Glycosylation improves the central effects of DAMGO.
Chemical biology & drug design 2007;69(1):41-7.
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2007: Lee Yeon Sun; Agnes Richard S; Davis Peg; Ma Shou-wu; Badghisi Hamid; Lai Josephine; Porreca Frank; Hruby Victor J
Partial retro-inverso, retro, and inverso modifications of hydrazide linked bifunctional peptides for opioid and cholecystokinin (CCK) receptors.
Journal of medicinal chemistry 2007;50(1):165-8.
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2006: Lai Josephine; Luo Miaw-Chyi; Chen Qingmin; Ma Shouwu; Gardell Luis R; Ossipov Michael H; Porreca Frank
Dynorphin A activates bradykinin receptors to maintain neuropathic pain.
Nature neuroscience 2006;9(12):1534-40.
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2006: Petrov Ravil R; Vardanyan Ruben S; Lee Yeon S; Ma Shou-wu; Davis Peg; Begay Lucinda J; Lai Josephine Y; Porreca Frank; Hruby Victor J
Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activity.
Bioorganic & medicinal chemistry letters 2006;16(18):4946-50.
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2006: King Tamara; Rao Srinivas; Vanderah Todd; Chen Qingmin; Vardanyan Anna; Porreca Frank
Differential blockade of nerve injury-induced shift in weight bearing and thermal and tactile hypersensitivity by milnacipran.
The journal of pain : official journal of the American Pain Society 2006;7(7):513-20.
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2006: Vera-Portocarrero L P; Zhang E-T; Ossipov M H; Xie J Y; King T; Lai J; Porreca F
Descending facilitation from the rostral ventromedial medulla maintains nerve injury-induced central sensitization.
Neuroscience 2006;140(4):1311-20.
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2006: Porreca F; Vanderah T W; Guo W; Barth M; Dodey P; Peyrou V; Luccarini J M; Junien J-L; Pruneau D
Antinociceptive pharmacology of N-[[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]methyl]-2-[2-[[(4-methoxy-2,6-dimethylphenyl) sulfonyl]methylamino]ethoxy]-N-methylacetamide, fumarate (LF22-0542), a novel nonpeptidic bradykinin B1 receptor antagonist.
The Journal of pharmacology and experimental therapeutics 2006;318(1):195-205.
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2006: Vera-Portocarrero Louis P; Xie Jennifer Y; Kowal Justin; Ossipov Michael H; King Tamara; Porreca Frank
Descending facilitation from the rostral ventromedial medulla maintains visceral pain in rats with experimental pancreatitis.
Gastroenterology 2006;130(7):2155-64.
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2006: Agnes Richard S; Lee Yeon Sun; Davis Peg; Ma Shou-Wu; Badghisi Hamid; Porreca Frank; Lai Josephine; Hruby Victor J
Structure-activity relationships of bifunctional peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors.
Journal of medicinal chemistry 2006;49(10):2868-75.
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2006: Ibrahim Mohab M; Rude Megan L; Stagg Nicola J; Mata Heriberto P; Lai Josephine; Vanderah Todd W; Porreca Frank; Buckley Nancy E; Makriyannis Alexandros; Malan T Philip
CB2 cannabinoid receptor mediation of antinociception.
Pain 2006;122(1-2):36-42.
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2006: Lee Yeon Sun; Agnes Richard S; Badghisi Hamid; Davis Peg; Ma Shou-wu; Lai Josephine; Porreca Frank; Hruby Victor J
Design and synthesis of novel hydrazide-linked bifunctional peptides as delta/mu opioid receptor agonists and CCK-1/CCK-2 receptor antagonists.
Journal of medicinal chemistry 2006;49(5):1773-80.
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2006: Gardell Luis R; King Tamara; Ossipov Michael H; Rice Kenner C; Lai Josephine; Vanderah Todd W; Porreca Frank
Opioid receptor-mediated hyperalgesia and antinociceptive tolerance induced by sustained opiate delivery.
Neuroscience letters 2006;396(1):44-9.
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2006: Mollica Adriano; Davis Peg; Ma Shou-Wu; Porreca Frank; Lai Josephine; Hruby Victor J
Synthesis and biological activity of the first cyclic biphalin analogues.
Bioorganic & medicinal chemistry letters 2006;16(2):367-72.
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2006: Hruby Victor J; Porreca Frank; Yamamura Henry I; Tollin Gordon; Agnes Richard S; Lee Yeon Sun; Cai Minying; Alves Isabel; Cowell Scott; Varga Eva; Davis Peg; Salamon Zdzislaw; Roeske William; Vanderah Todd; Lai Josephine
New paradigms and tools in drug design for pain and addiction.
The AAPS journal 2006;8(3):E450-60.
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2005: Dogrul Ahmet; Bilsky Edward J; Ossipov Michael H; Lai Josephine; Porreca Frank
Spinal L-type calcium channel blockade abolishes opioid-induced sensory hypersensitivity and antinociceptive tolerance.
Anesthesia and analgesia 2005;101(6):1730-5.
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2005: Ossipov Michael H; Porreca Frank
Challenges in the development of novel treatment strategies for neuropathic pain.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2005;2(4):650-61.
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2005: Malan T Philip; Porreca Frank
Lipid mediators regulating pain sensitivity.
Prostaglandins & other lipid mediators 2005;77(1-4):123-30.
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2005: King Tamara; Gardell Luis R; Wang Ruizhong; Vardanyan Anna; Ossipov Michael H; Malan T Philip; Vanderah Todd W; Hunt Stephen P; Hruby Victor J; Lai Josephine; Porreca Frank
Role of NK-1 neurotransmission in opioid-induced hyperalgesia.
Pain 2005;116(3):276-88.
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2005: Mollica Adriano; Davis Peg; Ma Shou-Wu; Lai Josephine; Porreca Frank; Hruby Victor J
Synthesis and biological evaluation of new biphalin analogues with non-hydrazine linkers.
Bioorganic & medicinal chemistry letters 2005;15(10):2471-5.
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2005: Dhanasekaran Muthu; Palian Michael M; Alves Isabel; Yeomans Larisa; Keyari Charles M; Davis Peg; Bilsky Edward J; Egleton Richard D; Yamamura Henry I; Jacobsen Neil E; Tollin Gordon; Hruby Victor J; Porreca Frank; Polt Robin
Glycopeptides related to beta-endorphin adopt helical amphipathic conformations in the presence of lipid bilayers.
Journal of the American Chemical Society 2005;127(15):5435-48.
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2005: Ibrahim Mohab M; Porreca Frank; Lai Josephine; Albrecht Phillip J; Rice Frank L; Khodorova Alla; Davar Gudarz; Makriyannis Alexandros; Vanderah Todd W; Mata Heriberto P; Malan T Philip
CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(8):3093-8.
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2005: Varga Eva V; Hosohata Keiko; Borys Dariusz; Navratilova Edita; Nylen Anders; Vanderah Todd W; Porreca Frank; Roeske William R; Yamamura Henry I
Antinociception depends on the presence of G protein gamma2-subunits in brain.
European journal of pharmacology 2005;508(1-3):93-8.
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2005: Xie Jennifer Y; Herman David S; Stiller Carl-Olav; Gardell Luis R; Ossipov Michael H; Lai Josephine; Porreca Frank; Vanderah Todd W
Cholecystokinin in the rostral ventromedial medulla mediates opioid-induced hyperalgesia and antinociceptive tolerance.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(2):409-16.
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2005: King Tamara; Ossipov Michael H; Vanderah Todd W; Porreca Frank; Lai Josephine
Is paradoxical pain induced by sustained opioid exposure an underlying mechanism of opioid antinociceptive tolerance?
Neuro-Signals 2005;14(4):194-205.
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2005: Luo Miaw-Chyi; Zhang Dong-Qin; Ma Shou-Wu; Huang Yuan-Yuan; Shuster Sam J; Porreca Frank; Lai Josephine
An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons.
Molecular pain 2005;1():29.
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2005: Sah Dinah W Y; Ossipov Michael H; Rossomando Anthony; Silvian Laura; Porreca Frank
New approaches for the treatment of pain: the GDNF family of neurotrophic growth factors.
Current topics in medicinal chemistry 2005;5(6):577-83.
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2005: Ossipov Michael H; Lai Josephine; King Tamara; Vanderah Todd W; Porreca Frank
Underlying mechanisms of pronociceptive consequences of prolonged morphine exposure.
Biopolymers 2005;80(2-3):319-24.
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2005: Gu Xuyuan; Ying Jinfa; Min Byoung; Cain James P; Davis Peg; Willey Patrick; Navratilova Edita; Yamamura Henry I; Porreca Frank; Hruby Victor J
Parallel synthesis and biological evaluation of different sizes of bicyclo[2,3]-Leu-enkephalin analogues.
Biopolymers 2005;80(2-3):151-63.
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2004: Ossipov Michael H; Lai Josephine; King Tamara; Vanderah Todd W; Malan T Philip; Hruby Victor J; Porreca Frank
Antinociceptive and nociceptive actions of opioids.
Journal of neurobiology 2004;61(1):126-48.
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2004: Elmagbari Nura O; Egleton Richard D; Palian Michael M; Lowery John J; Schmid Wendi R; Davis Peg; Navratilova Edita; Dhanasekaran Muthu; Keyari Charles M; Yamamura Henry I; Porreca Frank; Hruby Victor J; Polt Robin; Bilsky Edward J
Antinociceptive structure-activity studies with enkephalin-based opioid glycopeptides.
The Journal of pharmacology and experimental therapeutics 2004;311(1):290-7.
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2004: Gu Xuyuan; Ying Jinfa; Agnes Richard S; Navratilova Edita; Davis Peg; Stahl Gannon; Porreca Frank; Yamamura Henry I; Hruby Victor J
Novel design of bicyclic beta-turn dipeptides on solid-phase supports and synthesis of [3.3.0]-Bicyclo([2,3])-leu-enkephalin analogues.
Organic letters 2004;6(19):3285-8.
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2004: Chen Qingmin; King Tamara; Vanderah Todd W; Ossipov Michael H; Malan T Philip; Lai Josephine; Porreca Frank
Differential blockade of nerve injury-induced thermal and tactile hypersensitivity by systemically administered brain-penetrating and peripherally restricted local anesthetics.
The journal of pain : official journal of the American Pain Society 2004;5(5):281-9.
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2004: Quartilho Aline; Mata Heriberto P; Ibrahim Mohab M; Vanderah Todd W; Ossipov Michael H; Lai Josephine; Porreca Frank; Malan T Philip
Production of paradoxical sensory hypersensitivity by alpha 2-adrenoreceptor agonists.
Anesthesiology 2004;100(6):1538-44.
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2004: Alves Isabel; Cowell Scott; Lee Yeon Sun; Tang Xuejun; Davis Peg; Porreca Frank; Hruby Victor J
A novel 3-step enantioselective synthesis of pyrenylalanine with subsequent incorporation into opioid, CCK, and melanotropin ligands.
Biochemical and biophysical research communications 2004;318(2):335-40.
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2004: Ananthan Subramaniam; Khare Naveen K; Saini Surendra K; Seitz Lainne E; Bartlett Jeffrey L; Davis Peg; Dersch Christina M; Porreca Frank; Rothman Richard B; Bilsky Edward J
Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone].
Journal of medicinal chemistry 2004;47(6):1400-12.
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2004: Lai Josephine; Porreca Frank; Hunter John C; Gold Michael S
Voltage-gated sodium channels and hyperalgesia.
Annual review of pharmacology and toxicology 2004;44():371-97.
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2004: Gardell L R; Ibrahim M; Wang R; Wang Z; Ossipov M H; Malan T P; Porreca F; Lai J
Mouse strains that lack spinal dynorphin upregulation after peripheral nerve injury do not develop neuropathic pain.
Neuroscience 2004;123(1):43-52.
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2003: Gardell Luis R; Wang Ruizhong; Ehrenfels Chris; Ossipov Michael H; Rossomando Anthony J; Miller Stephan; Buckley Carolyn; Cai Amber K; Tse Albert; Foley Susan F; Gong BangJian; Walus Lee; Carmillo Paul; Worley Dane; Huang Carol; Engber Thomas; Pepinsky Blake; Cate Richard L; Vanderah Todd W; Lai Josephine; Sah Dinah W Y; Porreca Frank
Multiple actions of systemic artemin in experimental neuropathy.
Nature medicine 2003;9(11):1383-9.
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2003: Quartilho Aline; Mata Heriberto P; Ibrahim Mohab M; Vanderah Todd W; Porreca Frank; Makriyannis Alexandros; Malan T Philip
Inhibition of inflammatory hyperalgesia by activation of peripheral CB2 cannabinoid receptors.
Anesthesiology 2003;99(4):955-60.
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2003: Dogrul Ahmet; Gardell Luis R; Ossipov Michael H; Tulunay F Cankat; Lai Josephine; Porreca Frank
Reversal of experimental neuropathic pain by T-type calcium channel blockers.
Pain 2003;105(1-2):159-68.
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2003: Gardell L R; Vanderah T W; Gardell S E; Wang R; Ossipov M H; Lai J; Porreca F
Enhanced evoked excitatory transmitter release in experimental neuropathy requires descending facilitation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(23):8370-9.
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2003: Ananthan Subramaniam; Khare Naveen K; Saini Surendra K; Davis Peg; Dersch Christina M; Porreca Frank; Rothman Richard B
Novel ligands for the opioid receptors: synthesis and structure-activity relationships among 5'-aryl and 5'-heteroaryl 17-cyclopropylmethyl-4,5 alpha-epoxypyrido[2',3':6,7]morphinans.
Bioorganic & medicinal chemistry 2003;11(18):4143-54.
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2003: Ibrahim Mohab M; Deng Hongfeng; Zvonok Alexander; Cockayne Debra A; Kwan Joyce; Mata Heriberto P; Vanderah Todd W; Lai Josephine; Porreca Frank; Makriyannis Alexandros; Malan T Philip
Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(18):10529-33.
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2003: Xiong Chiyi; Zhang Junyi; Davis Peg; Wang Wei; Ying Jinfa; Porreca Frank; Hruby Victor J
Stereoselective synthesis of individual isomers of Leu-enkephalin analogues containing substituted beta-turn bicyclic dipeptide mimetics.
Chemical communications (Cambridge, England) 2003;(13):1598-9.
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2003: Lai Josephine; Hunter John C; Porreca Frank
The role of voltage-gated sodium channels in neuropathic pain.
Current opinion in neurobiology 2003;13(3):291-7.
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2003: Ossipov Michael H; Lai Josephine; Vanderah Todd W; Porreca Frank
Induction of pain facilitation by sustained opioid exposure: relationship to opioid antinociceptive tolerance.
Life sciences 2003;73(6):783-800.
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2003: Hruby V J; Agnes R S; Davis P; Ma S-W; Lee Y S; Vanderah T W; Lai J; Porreca F
Design of novel peptide ligands which have opioid agonist activity and CCK antagonist activity for the treatment of pain.
Life sciences 2003;73(6):699-704.
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2003: Sah Dinah W Y; Ossipo Michael H; Porreca Frank
Neurotrophic factors as novel therapeutics for neuropathic pain.
Nature reviews. Drug discovery 2003;2(6):460-72.
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2003: Ananthan Subramaniam; Kezar Hollis S; Saini Surendra K; Khare Naveen K; Davis Peg; Dersch Christina M; Porreca Frank; Rothman Richard B
Synthesis, opioid receptor binding, and functional activity of 5'-substituted 17-cyclopropylmethylpyrido[2',3':6,7]morphinans.
Bioorganic & medicinal chemistry letters 2003;13(3):529-32.
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2003: Malan T Philip; Ibrahim Mohab M; Lai Josephine; Vanderah Todd W; Makriyannis Alexandros; Porreca Frank
CB2 cannabinoid receptor agonists: pain relief without psychoactive effects?
Current opinion in pharmacology 2003;3(1):62-7.
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2003: Hosohata Keiko; Varga Eva V; Alfaro-Lopez Josue; Tang Xuejun; Vanderah Todd W; Porreca Frank; Hruby Victor J; Roeske William R; Yamamura Henry I
(2S,3R) beta-methyl-2',6'-dimethyltyrosine-L-tetrahydroisoquinoline-3-carboxylic acid [(2S,3R)TMT-L-Tic-OH] is a potent, selective delta-opioid receptor antagonist in mouse brain.
The Journal of pharmacology and experimental therapeutics 2003;304(2):683-8.
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2003: Wang R; Guo W; Ossipov M H; Vanderah T W; Porreca F; Lai J
Glial cell line-derived neurotrophic factor normalizes neurochemical changes in injured dorsal root ganglion neurons and prevents the expression of experimental neuropathic pain.
Neuroscience 2003;121(3):815-24.
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2002: Malan T Philip; Ibrahim Mohab M; Vanderah Todd W; Makriyannis Alexandros; Porreca Frank
Inhibition of pain responses by activation of CB(2) cannabinoid receptors.
Chemistry and physics of lipids 2002;121(1-2):191-200.
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2002: Gardell L R; Ossipov M H; Vanderah T W; Lai J; Porreca F
Dynorphin-independent spinal cannabinoid antinociception.
Pain 2002;100(3):243-8.
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2002: Dogrul Ahmet; Gardell Luis R; Ma Shouwu; Ossipov Michael H; Porreca Frank; Lai Josephine
'Knock-down' of spinal CB1 receptors produces abnormal pain and elevates spinal dynorphin content in mice.
Pain 2002;100(1-2):203-9.
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2002: Ossipov Michael H; Zhang En-Tan; Carvajal Cristina; Gardell Luis; Quirion Remi; Dumont Yvan; Lai Josephine; Porreca Frank
Selective mediation of nerve injury-induced tactile hypersensitivity by neuropeptide Y.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(22):9858-67.
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2002: Gardell Luis R; Wang Ruizhong; Burgess Shannon E; Ossipov Michael H; Vanderah Todd W; Malan T Philip; Lai Josephine; Porreca Frank
Sustained morphine exposure induces a spinal dynorphin-dependent enhancement of excitatory transmitter release from primary afferent fibers.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(15):6747-55.
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2002: Gardell L R; Burgess S E; Dogrul A; Ossipov M H; Malan T P; Lai J; Porreca F
Pronociceptive effects of spinal dynorphin promote cannabinoid-induced pain and antinociceptive tolerance.
Pain 2002;98(1-2):79-88.
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2002: Porreca Frank; Ossipov Michael H; Gebhart G F
Chronic pain and medullary descending facilitation.
Trends in neurosciences 2002;25(6):319-25.
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2002: Burgess Shannon E; Gardell Luis R; Ossipov Michael H; Malan T Philip; Vanderah Todd W; Lai Josephine; Porreca Frank
Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(12):5129-36.
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2002: Malan T Philip; Mata Heriberto P; Porreca Frank
Spinal GABA(A) and GABA(B) receptor pharmacology in a rat model of neuropathic pain.
Anesthesiology 2002;96(5):1161-7.
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2002: Lai Josephine; Gold Michael S; Kim Chang Sook; Bian Di; Ossipov Michael H; Hunter John C; Porreca Frank
Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8.
Pain 2002;95(1-2):143-52.
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2001: Malan T P; Ibrahim M M; Deng H; Liu Q; Mata H P; Vanderah T; Porreca F; Makriyannis A
CB2 cannabinoid receptor-mediated peripheral antinociception.
Pain 2001;93(3):239-45.
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2001: Lai J; Ossipov M H; Vanderah T W; Malan T P; Porreca F
Neuropathic pain: the paradox of dynorphin.
Molecular interventions 2001;1(3):160-7.
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2001: Ibrahim M M; Mata H P; Chawla M; Lai J; Porreca F; Malan T P
Allodynia and hyperalgesia produced by specific inhibition of spinal c-fos expression: lack of correlation with dynorphin content.
The journal of pain : official journal of the American Pain Society 2001;2(4):241-9.
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2001: Porreca F; Burgess S E; Gardell L R; Vanderah T W; Malan T P; Ossipov M H; Lappi D A; Lai J
Inhibition of neuropathic pain by selective ablation of brainstem medullary cells expressing the mu-opioid receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(14):5281-8.
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2001: Simoneau I I; Hamza M S; Mata H P; Siegel E M; Vanderah T W; Porreca F; Makriyannis A; Malan T P
The cannabinoid agonist WIN55,212-2 suppresses opioid-induced emesis in ferrets.
Anesthesiology 2001;94(5):882-7.
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2001: Vanderah T W; Ossipov M H; Lai J; Malan T P; Porreca F
Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin.
Pain 2001;92(1-2):5-9.
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2001: Liao S; Shenderovich M; Kövér K E; Zhang Z; Hosohata K; Davis P; Porreca F; Yamamura H I; Hurby V J
Synthesis, biology, NMR and conformation studies of the topographically constrained delta-opioid selective peptide analogs of [beta-iPrPhe(3)]deltorphin I.
The journal of peptide research : official journal of the American Peptide Society 2001;57(4):257-76.
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2001: Wang Z; Gardell L R; Ossipov M H; Vanderah T W; Brennan M B; Hochgeschwender U; Hruby V J; Malan T P; Lai J; Porreca F
Pronociceptive actions of dynorphin maintain chronic neuropathic pain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(5):1779-86.
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2001: Sun H; Ren K; Zhong C M; Ossipov M H; Malan T P; Lai J; Porreca F
Nerve injury-induced tactile allodynia is mediated via ascending spinal dorsal column projections.
Pain 2001;90(1-2):105-11.
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2001: Lipkowski A W; Misicka A; Hosohata K; Davis P; Yamamura H I; Porreca F; Hruby V J
Biological properties of Phe(o)-opioid peptide analogues.
Life sciences 2001;68(8):969-72.
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2001: Vanderah T W; Suenaga N M; Ossipov M H; Malan T P; Lai J; Porreca F
Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(1):279-86.
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2000: Dogrul A; Ossipov M H; Lai J; Malan T P; Porreca F
Peripheral and spinal antihyperalgesic activity of SIB-1757, a metabotropic glutamate receptor (mGLUR(5)) antagonist, in experimental neuropathic pain in rats.
Neuroscience letters 2000;292(2):115-8.
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2000: Vanderah T W; Gardell L R; Burgess S E; Ibrahim M; Dogrul A; Zhong C M; Zhang E T; Malan T P; Ossipov M H; Lai J; Porreca F
Dynorphin promotes abnormal pain and spinal opioid antinociceptive tolerance.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(18):7074-9.
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2000: Kovelowski C J; Ossipov M H; Sun H; Lai J; Malan T P; Porreca F
Supraspinal cholecystokinin may drive tonic descending facilitation mechanisms to maintain neuropathic pain in the rat.
Pain 2000;87(3):265-73.
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2000: Ossipov M H; Hong Sun T; Malan P; Lai J; Porreca F
Mediation of spinal nerve injury induced tactile allodynia by descending facilitatory pathways in the dorsolateral funiculus in rats.
Neuroscience letters 2000;290(2):129-32.
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2000: Ossipov M H; Jerussi T P; Ren K; Sun H; Porreca F
Differential effects of spinal (R)-ketoprofen and (S)-ketoprofen against signs of neuropathic pain and tonic nociception: evidence for a novel mechanism of action of (R)-ketoprofen against tactile allodynia.
Pain 2000;87(2):193-9.
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2000: Joshi S K; Su X; Porreca F; Gebhart G F
kappa -opioid receptor agonists modulate visceral nociception at a novel, peripheral site of action.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(15):5874-9.
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2000: Bilsky E J; Egleton R D; Mitchell S A; Palian M M; Davis P; Huber J D; Jones H; Yamamura H I; Janders J; Davis T P; Porreca F; Hruby V J; Polt R
Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability.
Journal of medicinal chemistry 2000;43(13):2586-90.
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2000: Tang Q; Lynch R M; Porreca F; Lai J
Dynorphin A elicits an increase in intracellular calcium in cultured neurons via a non-opioid, non-NMDA mechanism.
Journal of neurophysiology 2000;83(5):2610-5.
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2000: Malan T P; Ossipov M H; Gardell L R; Ibrahim M; Bian D; Lai J; Porreca F
Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats.
Pain 2000;86(1-2):185-94.
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2000: Bilsky E J; Qian X; Hruby V J; Porreca F
Antinociceptive activity of [beta-methyl-2', 6'-dimethyltyrosine(1)]-substituted cyclic [D-Pen(2), D-Pen(5)]Enkephalin and [D-Ala(2),Asp(4)]Deltorphin analogs.
The Journal of pharmacology and experimental therapeutics 2000;293(1):151-8.
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2000: Hosohata K; Logan J K; Varga E; Burkey T H; Vanderah T W; Porreca F; Hruby V J; Roeske W R; Yamamura H I
The role of the G protein gamma(2) subunit in opioid antinociception in mice.
European journal of pharmacology 2000;392(3):R9-R11.
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2000: Bonner G G; Davis P; Stropova D; Edsall S; Yamamura H I; Porreca F; Hruby V J
Opiate aromatic pharmacophore structure-activity relationships in CTAP analogues determined by topographical bias, two-dimensional NMR, and biological activity assays.
Journal of medicinal chemistry 2000;43(4):569-80.
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2000: Hosohata Y; Vanderah T W; Burkey T H; Ossipov M H; Kovelowski C J; Sora I; Uhl G R; Zhang X; Rice K C; Roeske W R; Hruby V J; Yamamura H I; Lai J; Porreca F
delta-Opioid receptor agonists produce antinociception and [35S]GTPgammaS binding in mu receptor knockout mice.
European journal of pharmacology 2000;388(3):241-8.
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2000: Ossipov M H; Lai J; Malan T P; Porreca F
Spinal and supraspinal mechanisms of neuropathic pain.
Annals of the New York Academy of Sciences 2000;909():12-24.
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2000: Lai J; Hunter J C; Ossipov M H; Porreca F
Blockade of neuropathic pain by antisense targeting of tetrodotoxin-resistant sodium channels in sensory neurons.
Methods in enzymology 2000;314():201-13.
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1999: Alfaro-Lopez J; Okayama T; Hosohata K; Davis P; Porreca F; Yamamura H I; Hruby V J
Exploring the structure-activity relationships of [1-(4-tert-butyl-3'-hydroxy)benzhydryl-4-benzylpiperazine] (SL-3111), a high-affinity and selective delta-opioid receptor nonpeptide agonist ligand.
Journal of medicinal chemistry 1999;42(26):5359-68.
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1999: Kovelowski C J; Ossipov M H; Hruby V J; Porreca F
Lesions of the dorsolateral funiculus block supraspinal opioid delta receptor mediated antinociception in the rat.
Pain 1999;83(2):115-22.
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1999: Tang Q; Gandhoke R; Burritt A; Hruby V J; Porreca F; Lai J
High-affinity interaction of (des-Tyrosyl)dynorphin A(2-17) with NMDA receptors.
The Journal of pharmacology and experimental therapeutics 1999;291(2):760-5.
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1999: Kovelowski C J; Bian D; Hruby V J; Lai J; Ossipov M H; Porreca F
Selective opioid delta agonists elicit antinociceptive supraspinal/spinal synergy in the rat.
Brain research 1999;843(1-2):12-7.
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1999: Lipkowski A W; Misicka A; Davis P; Stropova D; Janders J; Lachwa M; Porreca F; Yamamura H I; Hruby V J
Biological activity of fragments and analogues of the potent dimeric opioid peptide, biphalin.
Bioorganic & medicinal chemistry letters 1999;9(18):2763-6.
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1999: Ananthan S; Kezar H S; Carter R L; Saini S K; Rice K C; Wells J L; Davis P; Xu H; Dersch C M; Bilsky E J; Porreca F; Rothman R B
Synthesis, opioid receptor binding, and biological activities of naltrexone-derived pyrido- and pyrimidomorphinans.
Journal of medicinal chemistry 1999;42(18):3527-38.
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1999: Lashbrook J M; Ossipov M H; Hunter J C; Raffa R B; Tallarida R J; Porreca F
Synergistic antiallodynic effects of spinal morphine with ketorolac and selective COX1- and COX2-inhibitors in nerve-injured rats.
Pain 1999;82(1):65-72.
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1999: Porreca F; Lai J; Bian D; Wegert S; Ossipov M H; Eglen R M; Kassotakis L; Novakovic S; Rabert D K; Sangameswaran L; Hunter J C
A comparison of the potential role of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):7640-4.
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1999: Bian D; Ossipov M H; Ibrahim M; Raffa R B; Tallarida R J; Malan T P; Lai J; Porreca F
Loss of antiallodynic and antinociceptive spinal/supraspinal morphine synergy in nerve-injured rats: restoration by MK-801 or dynorphin antiserum.
Brain research 1999;831(1-2):55-63.
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1999: Owolabi J B; Rizkalla G; Tehim A; Ross G M; Riopelle R J; Kamboj R; Ossipov M; Bian D; Wegert S; Porreca F; Lee D K
Characterization of antiallodynic actions of ALE-0540, a novel nerve growth factor receptor antagonist, in the rat.
The Journal of pharmacology and experimental therapeutics 1999;289(3):1271-6.
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1999: Wang Z; Bilsky E J; Wang D; Porreca F; Sadée W
3-Isobutyl-1-methylxanthine inhibits basal mu-opioid receptor phosphorylation and reverses acute morphine tolerance and dependence in mice.
European journal of pharmacology 1999;371(1):1-9.
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1999: Bartosz-Bechowski H; Davis P; Slaninova J; Malatynska E; Stropova D; Porreca F; Yamamura H I; Hruby V J
Cyclic enkephalin analogs that are hybrids of DPDPE-related peptides and metenkephalin-Arg-Gly-Leu: prohormone analogs that retain good potency and selectivity for delta opioid receptors.
The journal of peptide research : official journal of the American Peptide Society 1999;53(3):329-36.
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1999: Ossipov M H; Bian D; Malan T P; Lai J; Porreca F
Lack of involvement of capsaicin-sensitive primary afferents in nerve-ligation injury induced tactile allodynia in rats.
Pain 1999;79(2-3):127-33.
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1998: Liao S; Alfaro-Lopez J; Shenderovich M D; Hosohata K; Lin J; Li X; Stropova D; Davis P; Jernigan K A; Porreca F; Yamamura H I; Hruby V J
De novo design, synthesis, and biological activities of high-affinity and selective non-peptide agonists of the delta-opioid receptor.
Journal of medicinal chemistry 1998;41(24):4767-76.
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1998: Ananthan S; Johnson C A; Carter R L; Clayton S D; Rice K C; Xu H; Davis P; Porreca F; Rothman R B
Synthesis, opioid receptor binding, and bioassay of naltrindole analogues substituted in the indolic benzene moiety.
Journal of medicinal chemistry 1998;41(15):2872-81.
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1998: Porreca F; Tang Q B; Bian D; Riedl M; Elde R; Lai J
Spinal opioid mu receptor expression in lumbar spinal cord of rats following nerve injury.
Brain research 1998;795(1-2):197-203.
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1998: Li G; Haq W; Xiang L; Lou B S; Hughes R; De Leon I A; Davis P; Gillespie T J; Romanowski M; Zhu X; Misicka A; Lipkowski A W; Porreca F; Davis T P; Yamamura H I; O'Brien D F; Hruby V J
Modifications of the 4,4'-residues and SAR studies of Biphalin, a highly potent opioid receptor active peptide.
Bioorganic & medicinal chemistry letters 1998;8(5):555-60.
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1998: Lu Y F; Xu H; Liu-Chen L Y; Chen C; Partilla J S; Brine G A; Carroll F I; Rice K C; Lai J; Porreca F; Sadee W; Rothman R B
Opioid peptide receptor studies. 7. The methylfentanyl congener RTI-4614-4 and its four enantiomers bind to different domains of the rat mu opioid receptor.
Synapse (New York, N.Y.) 1998;28(2):117-24.
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1998: Bian D; Ossipov M H; Zhong C; Malan T P; Porreca F
Tactile allodynia, but not thermal hyperalgesia, of the hindlimbs is blocked by spinal transection in rats with nerve injury.
Neuroscience letters 1998;241(2-3):79-82.
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1998: Vanderah T W; Raffa R B; Lashbrook J; Burritt A; Hruby V; Porreca F
Orphanin-FQ/nociceptin: lack of anti nociceptive, hyperalgesic or allodynic effects in acute thermal or mechanical tests following intracerebroventricular or intrathecal administration to mice or rats.
European journal of pain (London, England) 1998;2(3):267-78.
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1998: Kovelowski C J; Raffa R B; Porreca F
Tramadol and its enantiomers differentially suppress c-fos-like immunoreactivity in rat brain and spinal cord following acute noxious stimulus.
European journal of pain (London, England) 1998;2(3):211-9.
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1998: Ni Q; Xu H; Partilla J S; Rice K C; Matecka D; Calderon S N; Porreca F; Lai J; Schmidhammer H; Krassnig R; Rothman R B
Opioid peptide receptor studies. 9. Identification of a novel non-mu- non-delta-like opioid peptide binding site in rat brain.
Peptides 1998;19(6):1079-90.
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1998: Burkey T H; Ehlert F J; Hosohata Y; Quock R M; Cowell S; Hosohata K; Varga E; Stropova D; Li X; Slate C; Nagase H; Porreca F; Hruby V J; Roeske W R; Yamamura H I
The efficacy of delta-opioid receptor-selective drugs.
Life sciences 1998;62(17-18):1531-6.
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1998: Xu H; Lu Y F; Partilla J S; Pinto J; Calderon S N; Matecka D; Rice K C; Lai J; Porreca F; Ananthan S; Rothman R B
Opioid peptide receptor studies. 8. One of the mouse brain deltaNCX binding sites is similar to the cloned mouse opioid delta receptor: further evidence for heterogeneity of delta opioid receptors.
Peptides 1998;19(2):343-50.
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1997: Hruby V J; Bartosz-Bechowski H; Davis P; Slaninova J; Zalewska T; Stropova D; Porreca F; Yamamura H I
Cyclic enkephalin analogues with exceptional potency and selectivity for delta-opioid receptors.
Journal of medicinal chemistry 1997;40(24):3957-62.
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1997: Haaseth R C; Zalewska T; Davis P; Yamamura H I; Porreca F; Hruby V J
Para-substituted phenylalanine-4 analogues of [L-Ala3]DPDPE: highly selective delta opioid receptor ligands.
The journal of peptide research : official journal of the American Peptide Society 1997;50(3):171-7.
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1997: Laughlin T M; Vanderah T W; Lashbrook J; Nichols M L; Ossipov M; Porreca F; Wilcox G L
Spinally administered dynorphin A produces long-lasting allodynia: involvement of NMDA but not opioid receptors.
Pain 1997;72(1-2):253-60.
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1997: Misicka A; Cavagnero S; Horvath R; Davis P; Porreca F; Yamamura H I; Hruby V J
Synthesis and biological properties of beta-MePhe3 analogues of deltorphin I and dermenkephalin: influence of biased chi 1 Phe3 residues on peptide recognition for delta-opioid receptors.
The journal of peptide research : official journal of the American Peptide Society 1997;50(1):48-54.
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1997: Wegert S; Ossipov M H; Nichols M L; Bian D; Vanderah T W; Malan T P; Porreca F
Differential activities of intrathecal MK-801 or morphine to alter responses to thermal and mechanical stimuli in normal or nerve-injured rats.
Pain 1997;71(1):57-64.
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1997: Quock R M; Hosohata Y; Knapp R J; Burkey T H; Hosohata K; Zhang X; Rice K C; Nagase H; Hruby V J; Porreca F; Roeske W R; Yamamura H I
Relative efficacies of delta-opioid receptor agonists at the cloned human delta-opioid receptor.
European journal of pharmacology 1997;326(1):101-4.
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1997: Lai J; Crook T J; Payne A; Lynch R M; Porreca F
Antisense targeting of delta opioid receptors in NG 108-15 cells: direct correlation between oligodeoxynucleotide uptake and receptor density.
The Journal of pharmacology and experimental therapeutics 1997;281(1):589-96.
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1997: Nichols M L; Lopez Y; Ossipov M H; Bian D; Porreca F
Enhancement of the antiallodynic and antinociceptive efficacy of spinal morphine by antisera to dynorphin A (1-13) or MK-801 in a nerve-ligation model of peripheral neuropathy.
Pain 1997;69(3):317-22.
-
1997: Ossipov M H; Lopez Y; Bian D; Nichols M L; Porreca F
Synergistic antinociceptive interactions of morphine and clonidine in rats with nerve-ligation injury.
Anesthesiology 1997;86(1):196-204.
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1997: Bonner G G; Davis P; Stropova D; Ferguson R; Yamamura H I; Porreca F; Hruby V J
Opioid peptides: simultaneous delta agonism and mu antagonism in somatostatin analogues.
Peptides 1997;18(1):93-100.
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1997: Misicka A; Lipkowski A W; Horvath R; Davis P; Porreca F; Yamamura H I; Hruby V J
Structure-activity relationship of biphalin. The synthesis and biological activities of new analogues with modifications in positions 3 and 4.
Life sciences 1997;60(15):1263-9.
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