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Orso Bugiani

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Maria Luisa Moro; Annemieke Rozemuller; Stefania Saccucci; Andrea Uggetti; Dominic M Walsh; Nenad Bogdanovic; Orso Bugiani; Marcella Catania; Andrea Demarchi; Giuseppe Di Fede; Bernardino Ghetti; Giorgio Giaccone; Antonio Indaco; Raffaella Lombardi; Michela Morbin; Fabrizio Tagliavini
APP mutations in the Aβ coding region are associated with abundant cerebral deposition of Aβ38.
Giorgio Giaccone; Laura Orsi; Orso Bugiani; Patrizia Ferrero; Fabrizio Tagliavini
A case of multiple sclerosis with pure, massive superficial demyelination.
Orso Bugiani
Alzheimer's disease: ageing-related or age-related? New hypotheses from an old debate.

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2012: Maria Luisa Moro; Annemieke Rozemuller; Stefania Saccucci; Andrea Uggetti; Dominic M Walsh; Nenad Bogdanovic; Orso Bugiani; Marcella Catania; Andrea Demarchi; Giuseppe Di Fede; Bernardino Ghetti; Giorgio Giaccone; Antonio Indaco; Raffaella Lombardi; Michela Morbin; Fabrizio Tagliavini
APP mutations in the Aβ coding region are associated with abundant cerebral deposition of Aβ38.
Acta neuropathologica 2012;124(6):809-21.
2012: Giorgio Giaccone; Laura Orsi; Orso Bugiani; Patrizia Ferrero; Fabrizio Tagliavini
A case of multiple sclerosis with pure, massive superficial demyelination.
Neurology 2012;79(4):384-6.
2011: Orso Bugiani
Alzheimer's disease: ageing-related or age-related? New hypotheses from an old debate.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2011;32(6):1241-7.
2011: Maura Gallo; Silvana Geracitano; Enrico Ghidoni; Giorgio Giaccone; Raffaele Maletta; Norina Marcello; Maria Mirabelli; Gabriella Muraca; Gianfranco Puccio; Nicoletta Smirne; Fabrizio Tagliavini; Franca Vasso; Orso Bugiani; Alessandra Clodomiro; Rosanna Colao; S A M Curcio; Raffaele Di Lorenzo; Francesca Frangipane; Maria Anfossi; Livia Bernardi; Amalia C Bruni
A novel pathogenic PSEN1 mutation in a family with Alzheimer's disease: phenotypical and neuropathological features.
Journal of Alzheimer's disease : JAD 2011;25(3):425-31.
2011: Arianna Bellucci; Orso Bugiani; Bernardino Ghetti; Maria Grazia Spillantini
Presence of reactive microglia and neuroinflammatory mediators in a case of frontotemporal dementia with P301S mutation.
Neuro-degenerative diseases 2011;8(4):221-9.
2010: Simona Binelli; Pamela Agazzi; Laura Canafoglia; Vidmer Scaioli; Ferruccio Panzica; Elisa Visani; Giuseppe Di Fede; Giorgio Giaccone; Alberto Bizzi; Orso Bugiani; Giuliano Avanzini; Fabrizio Tagliavini; Silvana Franceschetti
Myoclonus in Creutzfeldt-Jakob disease: polygraphic and video-electroencephalography assessment of 109 patients.
Movement disorders : official journal of the Movement Disorder Society 2010;25(16):2818-27.
2010: Luigi Romito; Antonio E Elia; Angelo Franzini; Orso Bugiani; Alberto Albanese
Low-voltage bilateral pallidal stimulation for severe meige syndrome in a patient with primary segmental dystonia: case report.
Neurosurgery 2010;67(3 Suppl Operative):onsE308; discussion onsE308.
2010: Orso Bugiani; Giorgio Giaccone; Giacomina Rossi; Michela Mangieri; Raffaella Capobianco; Michela Morbin; Giulia Mazzoleni; Chiara Cupidi; Giordana Marcon; Annarita Giovagnoli; Alberto Bizzi; Giuseppe Di Fede; gianfranco puoti; F Carella; Andrea Salmaggi; Alessandro Romorini; Giorgio M Patruno; Mauro Magoni; Alessandro Padovani; Fabrizio Tagliavini
Hereditary cerebral hemorrhage with amyloidosis associated with the E693K mutation of APP.
Archives of neurology 2010;67(8):987-95.
2010: Chiara Cupidi; Raffaella Capobianco; Donato Goffredo; Giordana Marcon; Bernardino Ghetti; Orso Bugiani; Fabrizio Tagliavini; Giorgio Giaccone
Neocortical variation of Abeta load in fully expressed, pure Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;19(1):57-68.
2009: Irina Alafuzoff; Paul Geoffrey Ince; Thomas Arzberger; Safa Al-Sarraj; Jeanne Bell; Istvan Bodi; Nenad Bogdanovic; Orso Bugiani; Isidro Ferrer; Ellen Gelpi; Stephen M Gentleman; Giorgio Giaccone; James W Ironside; Nikolaos Kavantzas; Andrew King; Penelope Korkolopoulou; Gabor Geza Kovacs; David Meyronet; Camelia Monoranu; Piero Parchi; Laura Parkkinen; Efstratios Patsouris; Wolfgang Roggendorf; Annemieke Rozemuller; Christine Stadelmann-Nessler; Nathalie Streichenberger; Dietmar R Thal; Hans A Kretzschmar
Staging/typing of Lewy body related alpha-synuclein pathology: a study of the BrainNet Europe Consortium.
Acta neuropathologica 2009;117(6):635-52.
2009: Giorgio Giaccone; Marina Grisoli; Lucia Limido; Michela Mangieri; Silvia Suardi; Simona Binelli; Orso Bugiani; Raffaella Capobianco; Giuseppe Di Fede; Paolo Fociani; Fabrizio Tagliavini
A novel phenotype of sporadic Creutzfeldt-Jakob disease.
BMJ case reports 2009;2009():.
2008: Irina Alafuzoff; Thomas Arzberger; Safa Al-Sarraj; Istvan Bodi; Nenad Bogdanovic; Heiko Braak; Orso Bugiani; Kelly Del Tredici; Isidro Ferrer; Ellen Gelpi; Giorgio Giaccone; Manuel B Graeber; Paul Ince; Wouter Kamphorst; Andrew King; Penelope Korkolopoulou; Gabor Geza Kovacs; Sergey Larionov; David Meyronet; Camelia Monoranu; Piero Parchi; Efstratios Patsouris; Wolfgang Roggendorf; Danielle Seilhean; Fabrizio Tagliavini; Christine Stadelmann; Nathalie Streichenberger; Dietmar R Thal; Stephen B Wharton; Hans A Kretzschmar
Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium.
Brain pathology (Zurich, Switzerland) 2008;18(4):484-96.
2008: Anna R Giovagnoli; Alessandra Erbetta; Fabiola Reati; Orso Bugiani
Differential neuropsychological patterns of frontal variant frontotemporal dementia and Alzheimer's disease in a study of diagnostic concordance.
Neuropsychologia 2008;46(5):1495-504.
2007: Giorgio Giaccone; Giuseppe Di Fede; Michela Mangieri; Lucia Limido; Raffaella Capobianco; Silvia Suardi; Marina Grisoli; Simona Binelli; Paolo Fociani; Orso Bugiani; Fabrizio Tagliavini
A novel phenotype of sporadic Creutzfeldt-Jakob disease.
Journal of neurology, neurosurgery, and psychiatry 2007;78(12):1379-82.
2007: Angelo Franzini; Carlo Marras; G Tringali; M Leone; Paolo Ferroli; G Bussone; Orso Bugiani; Giovanni Broggi
Chronic high frequency stimulation of the posteromedial hypothalamus in facial pain syndromes and behaviour disorders.
Acta neurochirurgica. Supplement 2007;97(Pt 2):399-406.
2006: Irina Alafuzoff; Maria Pikkarainen; Safa Al-Sarraj; Thomas Arzberger; Jeanne Bell; Istvan Bodi; Nenad Bogdanovic; Herbert Budka; Orso Bugiani; Isidro Ferrer; Ellen Gelpi; Giorgio Giaccone; Manuel B Graeber; JEAN-JACQUES HAUW; Wouter Kamphorst; Andrew King; Nicolas Kopp; Penelope Korkolopoulou; Gabor Geza Kovacs; David Meyronet; Piero Parchi; Efstratios Patsouris; Matthias Preusser; Rivka Ravid; Wolfgang Roggendorf; Danielle Seilhean; Nathalie Streichenberger; Dietmar R Thal; Hans A Kretzschmar
Interlaboratory comparison of assessments of Alzheimer disease-related lesions: a study of the BrainNet Europe Consortium.
Journal of neuropathology and experimental neurology 2006;65(8):740-57.
2006: Orso Bugiani
Neuropathology of the dementias other than Alzheimer's.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2006;27 Suppl 1():S44-6.
2006: Simona Binelli; Pamela Agazzi; Giorgio Giaccone; Robert G Will; Orso Bugiani; Silvana Franceschetti; Fabrizio Tagliavini
Periodic electroencephalogram complexes in a patient with variant Creutzfeldt-Jakob disease.
Annals of neurology 2006;59(2):423-7.
2005: Giorgio Giaccone; Giacomina Rossi; Laura Farina; Giordana Marcon; Giuseppe Di Fede; Marcella Catania; Michela Morbin; Leonardo Sacco; Orso Bugiani; Fabrizio Tagliavini
Familial frontotemporal dementia associated with the novel MAPT mutation T427M.
Journal of neurology 2005;252(12):1543-5.
2005: gianfranco puoti; Giorgio Giaccone; Michela Mangieri; Lucia Limido; Paolo Fociani; Pietro Zerbi; Silvia Suardi; Giacomina Rossi; Selina Iussich; Raffaella Capobianco; Giuseppe Di Fede; Giordana Marcon; Roberto Cotrufo; Graziella Filippini; Orso Bugiani; Fabrizio Tagliavini
Sporadic Creutzfeldt-Jakob disease: the extent of microglia activation is dependent on the biochemical type of PrPSc.
Journal of neuropathology and experimental neurology 2005;64(10):902-9.
2005: Angelo Franzini; Carlo Marras; Paolo Ferroli; Giovanna Zorzi; Orso Bugiani; Luigi Romito; Giovanni Broggi
Long-term high-frequency bilateral pallidal stimulation for neuroleptic-induced tardive dystonia. Report of two cases.
Journal of neurosurgery 2005;102(4):721-5.
2005: Elisa Visani; Pamela Agazzi; Vidmer Scaioli; Giorgio Giaccone; Simona Binelli; Laura Canafoglia; Ferruccio Panzica; Fabrizio Tagliavini; Orso Bugiani; Giuliano Avanzini; Silvana Franceschetti
FVEPs in Creutzfeldt-Jacob disease: waveforms and interaction with the periodic EEG pattern assessed by single sweep analysis.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2005;116(4):895-904.
2005: Angelo Franzini; Carlo Marras; Paolo Ferroli; Orso Bugiani; Giovanni Broggi
Stimulation of the posterior hypothalamus for medically intractable impulsive and violent behavior.
Stereotactic and functional neurosurgery 2005;83(2-3):63-6.
2004: Giacomina Rossi; Giorgio Giaccone; Raffaele Maletta; Michela Morbin; Raffaella Capobianco; Michela Mangieri; Anna Rita Giovagnoli; A Bizzi; Carmine Tomaino; Maria Perri; Manuela Di Natale; Fabrizio Tagliavini; Orso Bugiani; Amalia C Bruni
A family with Alzheimer disease and strokes associated with A713T mutation of the APP gene.
Neurology 2004;63(5):910-2.
2004: Giordana Marcon; Giorgio Giaccone; Chiara Cupidi; Matteo Balestrieri; Carlo Alberto Beltrami; Nicoletta Finato; Paolo Bergonzi; Sandro Sorbi; Orso Bugiani; Fabrizio Tagliavini
Neuropathological and clinical phenotype of an Italian Alzheimer family with M239V mutation of presenilin 2 gene.
Journal of neuropathology and experimental neurology 2004;63(3):199-209.
2004: Orso Bugiani
A beta-related cerebral amyloid angiopathy.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2004;25 Suppl 1():S1-2.
2003: Mario Salmona; Michela Morbin; Tania Massignan; Laura Colombo; Giulia Mazzoleni; Raffaella Capobianco; Luisa Diomede; Florian Thaler; Luca Mollica; Giovanna Musco; Joseph J Kourie; Orso Bugiani; Deepak Sharma; Hideyo Inouye; Daniel A Kirschner; Gianluigi Forloni; Fabrizio Tagliavini
Structural properties of Gerstmann-Straussler-Scheinker disease amyloid protein.
The Journal of biological chemistry 2003;278(48):48146-53.
2003: Vladimiro Pietrini; gianfranco puoti; Lucia Limido; Giacomina Rossi; Giuseppe Di Fede; Giorgio Giaccone; Michela Mangieri; F Tedeschi; A Bondavalli; Domenico Mancia; Orso Bugiani; Fabrizio Tagliavini
Creutzfeldt-Jakob disease with a novel extra-repeat insertional mutation in the PRNP gene.
Neurology 2003;61(9):1288-91.
2003: Paola Soliveri; Giacomina Rossi; Daniela Monza; Fabrizio Tagliavini; Sylvie Piacentini; Alberto Albanese; Orso Bugiani; Floriano Girotti
A case of dementia parkinsonism resembling progressive supranuclear palsy due to mutation in the tau protein gene.
Archives of neurology 2003;60(10):1454-6.
2003: Giacomina Rossi; Mario Salmona; Gianluigi Forloni; Orso Bugiani; Fabrizio Tagliavini
Therapeutic approaches to prion diseases.
Clinics in laboratory medicine 2003;23(1):187-208.
2003: Bernardino Ghetti; Fabrizio Tagliavini; M Takao; Orso Bugiani; Pedro Piccardo
Hereditary prion protein amyloidoses.
Clinics in laboratory medicine 2003;23(1):65-85, viii.
2002: Gianluigi Forloni; Selina Iussich; Tazeen Awan; Laura Colombo; Nadia Angeretti; Laura Girola; Ilaria Bertani; Giorgio Poli; Maria Caramelli; Maria Grazia Bruzzone; Laura Farina; Lucia Limido; Giacomina Rossi; Giorgio Giaccone; James W Ironside; Orso Bugiani; Mario Salmona; Fabrizio Tagliavini
Tetracyclines affect prion infectivity.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10849-54.
2001: Anna Rita Giovagnoli; Alessandra Erbetta; Orso Bugiani
Preserved semantic access in global amnesia and hippocampal damage.
The Clinical neuropsychologist 2001;15(4):508-15.
2001: Masaki Takao; Bernardino Ghetti; Jill R Murrell; Frederick W Unverzagt; G Giaccone; Fabrizio Tagliavini; Orso Bugiani; Pedro Piccardo; Christine M Hulette; Barbara J Crain; Martin R Farlow; Albert Heyman
Ectopic white matter neurons, a developmental abnormality that may be caused by the PSEN1 S169L mutation in a case of familial AD with myoclonus and seizures.
Journal of neuropathology and experimental neurology 2001;60(12):1137-52.
2001: Pedro Piccardo; Juris J Liepnieks; A William; Stephen R Dlouhy; Martin R Farlow; K Young; David Nochlin; Thomas D Bird; R R Nixon; Melvyn Ball; Charles DeCarli; Orso Bugiani; Fabrizio Tagliavini; M D Benson; Bernardino Ghetti
Prion proteins with different conformations accumulate in Gerstmann-Sträussler-Scheinker disease caused by A117V and F198S mutations.
The American journal of pathology 2001;158(6):2201-7.
2001: Fabrizio Tagliavini; PM Lievens; C Tranchant; J M Warter; M Mohr; Giorgio Giaccone; F Perini; Giacomina Rossi; Mario Salmona; Pedro Piccardo; Bernardino Ghetti; Ronald C Beavis; Orso Bugiani; Blas Frangione; Frances Prelli
A 7-kDa prion protein (PrP) fragment, an integral component of the PrP region required for infectivity, is the major amyloid protein in Gerstmann-Sträussler-Scheinker disease A117V.
The Journal of biological chemistry 2001;276(8):6009-15.
2001: Fabrizio Tagliavini; Gianluigi Forloni; P D'Ursi; Orso Bugiani; M Salmona
Studies on peptide fragments of prion proteins.
Advances in protein chemistry 2001;57():171-201.
2000: Giacomina Rossi; Giorgio Giaccone; L Giampaolo; Selina Iussich; gianfranco puoti; Maura Frigo; Guido Cavaletti; Lodovico Frattola; Orso Bugiani; Fabrizio Tagliavini
Creutzfeldt-Jakob disease with a novel four extra-repeat insertional mutation in the PrP gene.
Neurology 2000;55(3):405-10.
2000: gianfranco puoti; Giacomina Rossi; Giorgio Giaccone; Tazeen Awan; PM Lievens; C A Defanti; Fabrizio Tagliavini; Orso Bugiani
Polymorphism at codon 129 of PRNP affects the phenotypic expression of Creutzfeldt-Jakob disease linked to E200K mutation.
Annals of neurology 2000;48(2):269-70.
2000: Fabrizio Tagliavini; Gianluigi Forloni; Laura Colombo; Giacomina Rossi; Laura Girola; B Canciani; Nadia Angeretti; L Giampaolo; E Peressini; Tazeen Awan; Luca De Gioia; Enzio Ragg; Orso Bugiani; Mario Salmona
Tetracycline affects abnormal properties of synthetic PrP peptides and PrP(Sc) in vitro.
Journal of molecular biology 2000;300(5):1309-22.
2000: Orso Bugiani; G Giaccone; Pedro Piccardo; Michela Morbin; Fabrizio Tagliavini; Bernardino Ghetti
Neuropathology of Gerstmann-Sträussler-Scheinker disease.
Microscopy research and technique 2000;50(1):10-5.
2000: Nardo Nardocci; Michela Morbin; Massimiliano Bugiani; Eleonora Lamantea; Orso Bugiani
Neuronal ceroid lipofuscinosis: detection of atypical forms.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2000;21(3 Suppl):S57-61.
2000: Giorgio Giaccone; B Canciani; gianfranco puoti; Giacomina Rossi; D Goffredo; Selina Iussich; Paolo Fociani; Fabrizio Tagliavini; Orso Bugiani
Creutzfeldt-Jakob disease: Carnoy's fixative improves the immunohistochemistry of the proteinase K-resistant prion protein.
Brain pathology (Zurich, Switzerland) 2000;10(1):31-7.
1999: gianfranco puoti; Giorgio Giaccone; Giacomina Rossi; B Canciani; Orso Bugiani; Fabrizio Tagliavini
Sporadic Creutzfeldt-Jakob disease: co-occurrence of different types of PrP(Sc) in the same brain.
Neurology 1999;53(9):2173-6.
1999: Enzio Ragg; Fabrizio Tagliavini; P Malesani; L Monticelli; Orso Bugiani; Gianluigi Forloni; Mario Salmona
Determination of solution conformations of PrP106-126, a neurotoxic fragment of prion protein, by 1H NMR and restrained molecular dynamics.
European journal of biochemistry / FEBS 1999;266(3):1192-201.
1999: Mario Salmona; P Malesani; Luca De Gioia; S Gorla; M Bruschi; A Molinari; F Della Vedova; B Pedrotti; M A Marrari; Tazeen Awan; Orso Bugiani; Gianluigi Forloni; Fabrizio Tagliavini
Molecular determinants of the physicochemical properties of a critical prion protein region comprising residues 106-126.
The Biochemical journal 1999;342 ( Pt 1)():207-14.
1999: Orso Bugiani; Jill R Murrell; Giorgio Giaccone; M Hasegawa; G Ghigo; Massimo Tabaton; Michela Morbin; Alberto Primavera; F Carella; Claudio Solaro; Marina Grisoli; Mario Savoiardo; Maria Grazia Spillantini; Fabrizio Tagliavini; Michel Goedert; Bernardino Ghetti
Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau.
Journal of neuropathology and experimental neurology 1999;58(6):667-77.
1999: Nardo Nardocci; Giovanna Zorzi; Laura Farina; Simona Binelli; W Scaioli; Claudia Ciano; L Verga; Lucia Angelini; Mario Savoiardo; Orso Bugiani
Infantile neuroaxonal dystrophy: clinical spectrum and diagnostic criteria.
Neurology 1999;52(7):1472-8.
1999: Giordana Marcon; G Giaccone; B Canciani; L Cajola; G Rossi; Luca De Gioia; M Salmona; Orso Bugiani; Fabrizio Tagliavini
A betaPP peptide carboxyl-terminal to Abeta is neurotoxic.
The American journal of pathology 1999;154(4):1001-7.
1999: Orso Bugiani
Pathogenesis of Alzheimer's disease and dementia.
Revue neurologique 1999;155 Suppl 4():S28-32.
1998: Pedro Piccardo; Stephen R Dlouhy; PM Lievens; K Young; Thomas D Bird; David Nochlin; dennis dickson; Harry V Vinters; T R Zimmerman; I R Mackenzie; Stephen J Kish; Lee Cyn Ang; Charles DeCarli; Maurizio Pocchiari; Paul Brown; CJ Gibbs; D Carleton Gajdusek; Orso Bugiani; James Ironside; Fabrizio Tagliavini; Bernardino Ghetti
Phenotypic variability of Gerstmann-Sträussler-Scheinker disease is associated with prion protein heterogeneity.
Journal of neuropathology and experimental neurology 1998;57(10):979-88.
1998: Pedro Piccardo; J P Langeveld; Andrew Hill; Stephen R Dlouhy; K Young; G Giaccone; G Rossi; M Bugiani; Orso Bugiani; R H Meloen; J Collinge; Fabrizio Tagliavini; Bernardino Ghetti
An antibody raised against a conserved sequence of the prion protein recognizes pathological isoforms in human and animal prion diseases, including Creutzfeldt-Jakob disease and bovine spongiform encephalopathy.
The American journal of pathology 1998;152(6):1415-20.
1998: Giacomina Rossi; G Macchi; M Porro; Giorgio Giaccone; M Bugiani; E Scarpini; G Scarlato; G E Molini; F Sasanelli; Orso Bugiani; Fabrizio Tagliavini
Fatal familial insomnia: genetic, neuropathologic, and biochemical study of a patient from a new Italian kindred.
Neurology 1998;50(3):688-92.
1997: G Macchi; G Rossi; A L Abbamondi; Giorgio Giaccone; Domenico Mancia; Fabrizio Tagliavini; Orso Bugiani
Diffuse thalamic degeneration in fatal familial insomnia. A morphometric study.
Brain research 1997;771(1):154-8.
1997: Fabrizio Tagliavini; Robert McArthur; B Canciani; Giorgio Giaccone; M Porro; M Bugiani; PM Lievens; Orso Bugiani; E Peri; Paola Dall'Ara; Mara Rocchi; Giorgio Poli; Gianluigi Forloni; T Bandiera; Mario Varasi; A Suarato; P Cassutti; MA Cervini; J Lansen; Mario Salmona; C Post
Effectiveness of anthracycline against experimental prion disease in Syrian hamsters.
Science (New York, N.Y.) 1997;276(5315):1119-22.
1997: Mario Salmona; Gianluigi Forloni; Luisa Diomede; M Algeri; Luca De Gioia; Nadia Angeretti; Giorgio Giaccone; Fabrizio Tagliavini; Orso Bugiani
A neurotoxic and gliotrophic fragment of the prion protein increases plasma membrane microviscosity.
Neurobiology of disease 1997;4(1):47-57.
1996: Luisa Diomede; Silvano Sozzani; Walter Luini; M Algeri; Luca De Gioia; R Chiesa; PM Lievens; Orso Bugiani; Gianluigi Forloni; Fabrizio Tagliavini; Mario Salmona
Activation effects of a prion protein fragment [PrP-(106-126)] on human leucocytes.
The Biochemical journal 1996;320 ( Pt 2)():563-70.
1996: Pedro Piccardo; C Seiler; Stephen R Dlouhy; K Young; Martin R Farlow; F Prelli; Blas Frangione; Orso Bugiani; Fabrizio Tagliavini; Bernardino Ghetti
Proteinase-K-resistant prion protein isoforms in Gerstmann-Sträussler-Scheinker disease (Indiana kindred).
Journal of neuropathology and experimental neurology 1996;55(11):1157-63.
1996: Gianluigi Forloni; Fabrizio Tagliavini; Orso Bugiani; Mario Salmona
Amyloid in Alzheimer's disease and prion-related encephalopathies: studies with synthetic peptides.
Progress in neurobiology 1996;49(4):287-315.
1996: Bernardino Ghetti; Pedro Piccardo; Blas Frangione; Orso Bugiani; Giorgio Giaccone; K Young; F Prelli; Martin R Farlow; Stephen R Dlouhy; Fabrizio Tagliavini
Prion protein amyloidosis.
Brain pathology (Zurich, Switzerland) 1996;6(2):127-45.
1996: Roberto Chiesa; Nadia Angeretti; E Lucca; Mario Salmona; Fabrizio Tagliavini; Orso Bugiani; Gianluigi Forloni
Clusterin (SGP-2) induction in rat astroglial cells exposed to prion protein fragment 106-126.
The European journal of neuroscience 1996;8(3):589-97.
1996: Bernardino Ghetti; Pedro Piccardo; Maria Grazia Spillantini; Y Ichimiya; M Porro; F Perini; T Kitamoto; J Tateishi; C Seiler; Blas Frangione; Orso Bugiani; Giorgio Giaccone; F Prelli; Michel Goedert; Stephen R Dlouhy; Fabrizio Tagliavini
Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(2):744-8.
1996: Giorgio Giaccone; B Pedrotti; antonio migheli; L Verga; J Perez; G Racagni; Mark A. Smith; George Perry; Luca De Gioia; C Selvaggini; Mario Salmona; Jorge Ghiso; Blas Frangione; K Islam; Orso Bugiani; Fabrizio Tagliavini
beta PP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease.
The American journal of pathology 1996;148(1):79-87.
1995: Pedro Piccardo; Bernardino Ghetti; dennis dickson; Harry V Vinters; Giorgio Giaccone; Orso Bugiani; Fabrizio Tagliavini; K Young; Stephen R Dlouhy; C Seiler
Gerstmann-Sträussler-Scheinker disease (PRNP P102L): amyloid deposits are best recognized by antibodies directed to epitopes in PrP region 90-165.
Journal of neuropathology and experimental neurology 1995;54(6):790-801.
1995: Nardo Nardocci; M L Verga; Simona Binelli; Giovanna Zorzi; Lucia Angelini; Orso Bugiani
Neuronal ceroid-lipofuscinosis: a clinical and morphological study of 19 patients.
American journal of medical genetics 1995;57(2):137-41.
1995: Orso Bugiani; Fabrizio Tagliavini; Giorgio Giaccone; L Verga; Khalid H El Hachimi; J F Foncin; Blas Frangione
Diffuse senile plaques: amorphous or fibrous?
The American journal of pathology 1995;146(3):777-9.
1995: Bernardino Ghetti; Stephen R Dlouhy; Giorgio Giaccone; Orso Bugiani; Blas Frangione; Martin R Farlow; Fabrizio Tagliavini
Gerstmann-Sträussler-Scheinker disease and the Indiana kindred.
Brain pathology (Zurich, Switzerland) 1995;5(1):61-75.
1994: Fabrizio Tagliavini; F Prelli; M Porro; Giacomina Rossi; Giorgio Giaccone; Martin R Farlow; Stephen R Dlouhy; Bernardino Ghetti; Orso Bugiani; Blas Frangione
Amyloid fibrils in Gerstmann-Sträussler-Scheinker disease (Indiana and Swedish kindreds) express only PrP peptides encoded by the mutant allele.
Cell 1994;79(4):695-703.
1994: Martin R Farlow; Bernardino Ghetti; Stephen R Dlouhy; Giorgio Giaccone; Orso Bugiani; Fabrizio Tagliavini; S Wagner
Cerebrospinal fluid levels of amyloid beta-protein precursor are low in Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
Neurology 1994;44(8):1508-10.
1994: Ivana Magnani; S Guerneri; Bianca Pollo; Nicola Cirenei; B M Colombo; Giovanni Broggi; C Galli; Orso Bugiani; S DiDonato; Gaetano Finocchiaro
Increasing complexity of the karyotype in 50 human gliomas. Progressive evolution and de novo occurrence of cytogenetic alterations.
Cancer genetics and cytogenetics 1994;75(2):77-89.
1994: Luca De Gioia; C Selvaggini; Elena Ghibaudi; Luisa Diomede; Orso Bugiani; Gianluigi Forloni; Fabrizio Tagliavini; Mario Salmona
Conformational polymorphism of the amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein.
The Journal of biological chemistry 1994;269(11):7859-62.
1994: Bernardino Ghetti; Fabrizio Tagliavini; Giorgio Giaccone; Orso Bugiani; Blas Frangione; Martin R Farlow; Stephen R Dlouhy
Familial Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles.
Molecular neurobiology 1994;8(1):41-8.
1993: Roberto Spreafico; Lucia Angelini; Simona Binelli; Tiziana Granata; V Rumi; D Rosti; L Runza; Orso Bugiani
Burst suppression and impairment of neocortical ontogenesis: electroclinical and neuropathologic findings in two infants with early myoclonic encephalopathy.
Epilepsia 1993;34(5):800-8.
1993: C Selvaggini; Luca De Gioia; L Cantù; Elena Ghibaudi; Luisa Diomede; F Passerini; Gianluigi Forloni; Orso Bugiani; Fabrizio Tagliavini; Mario Salmona
Molecular characteristics of a protease-resistant, amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein.
Biochemical and biophysical research communications 1993;194(3):1380-6.
1993: Fabrizio Tagliavini; Giorgio Giaccone; F Prelli; L Verga; M Porro; John Q Trojanowski; Martin R Farlow; Blas Frangione; Bernardino Ghetti; Orso Bugiani
A68 is a component of paired helical filaments of Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
Brain research 1993;616(1-2):325-9.
1993: Gianluigi Forloni; Nadia Angeretti; Roberto Chiesa; E Monzani; Mario Salmona; Orso Bugiani; Fabrizio Tagliavini
Neurotoxicity of a prion protein fragment.
Nature 1993;362(6420):543-6.
1993: Fabrizio Tagliavini; Giorgio Giaccone; Orso Bugiani; Blas Frangione
Ubiquitinated neurites are associated with preamyloid and cerebral amyloid beta deposits in patients with hereditary cerebral hemorrhage with amyloidosis Dutch type.
Acta neuropathologica 1993;85(3):267-71.
1993: Orso Bugiani; Giorgio Giaccone; L Verga; Bianca Pollo; Blas Frangione; Martin R Farlow; Fabrizio Tagliavini; Bernardino Ghetti
Beta PP participates in PrP-amyloid plaques of Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
Journal of neuropathology and experimental neurology 1993;52(1):64-70.
1992: Giorgio Giaccone; L Verga; Orso Bugiani; Blas Frangione; D Serban; Stanley B Prusiner; Martin R Farlow; Bernardino Ghetti; Fabrizio Tagliavini
Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):9349-53.
1992: Fabrizio Tagliavini; F Prelli; M Porro; Mario Salmona; Orso Bugiani; Blas Frangione
A soluble form of prion protein in human cerebrospinal fluid: implications for prion-related encephalopathies.
Biochemical and biophysical research communications 1992;184(3):1398-404.
1992: Fabrizio Tagliavini; Giorgio Giaccone; L Verga; Blas Frangione; Orso Bugiani
Down syndrome as a key to the time sequence of brain changes in Alzheimer disease.
Progress in clinical and biological research 1992;379():143-58.
1991: Khalid H El Hachimi; L Verga; Giorgio Giaccone; Fabrizio Tagliavini; Blas Frangione; Orso Bugiani; Jean Francois Foncin
Relationship between non-fibrillary amyloid precursors and cell processes in the cortical neuropil of Alzheimer patients.
Neuroscience letters 1991;129(1):119-22.
1991: Fabrizio Tagliavini; Giorgio Giaccone; L Verga; Jorge Ghiso; Blas Frangione; Orso Bugiani
Alzheimer patients: preamyloid deposits are immunoreactive with antibodies to extracellular domains of the amyloid precursor protein.
Neuroscience letters 1991;128(1):117-20.
1991: Fabrizio Tagliavini; F Prelli; Jorge Ghiso; Orso Bugiani; D Serban; Stanley B Prusiner; Martin R Farlow; Bernardino Ghetti; Blas Frangione
Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58.
The EMBO journal 1991;10(3):513-9.
1990: Orso Bugiani; Giorgio Giaccone; L Verga; Bianca Pollo; Bernardino Ghetti; Blas Frangione; Fabrizio Tagliavini
Alzheimer patients and Down patients: abnormal presynaptic terminals are related to cerebral preamyloid deposits.
Neuroscience letters 1990;119(1):56-9.
1990: Giorgio Giaccone; Fabrizio Tagliavini; L Verga; Blas Frangione; Martin R Farlow; Orso Bugiani; Bernardino Ghetti
Neurofibrillary tangles of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease share antigenic determinants with those of Alzheimer disease.
Brain research 1990;530(2):325-9.
1990: Giorgio Giaccone; L Verga; M Finazzi; Bianca Pollo; Fabrizio Tagliavini; Blas Frangione; Orso Bugiani
Cerebral preamyloid deposits and congophilic angiopathy in aged dogs.
Neuroscience letters 1990;114(2):178-83.
1989: L Verga; Blas Frangione; Fabrizio Tagliavini; Giorgio Giaccone; antonio migheli; Orso Bugiani
Alzheimer patients and Down patients: cerebral preamyloid deposits differ ultrastructurally and histochemically from the amyloid of senile plaques.
Neuroscience letters 1989;105(3):294-9.
1989: Orso Bugiani; Giorgio Giaccone; Blas Frangione; Bernardino Ghetti; Fabrizio Tagliavini
Alzheimer patients: preamyloid deposits are more widely distributed than senile plaques throughout the central nervous system.
Neuroscience letters 1989;103(3):263-8.
1989: Giorgio Giaccone; Fabrizio Tagliavini; G Linoli; Constantin Bouras; L Frigerio; Blas Frangione; Orso Bugiani
Down patients: extracellular preamyloid deposits precede neuritic degeneration and senile plaques.
Neuroscience letters 1989;97(1-2):232-8.
1989: Fabrizio Tagliavini; Giorgio Giaccone; G Linoli; Blas Frangione; Orso Bugiani
Cerebral extracellular preamyloid deposits in Alzheimer's disease, Down syndrome and nondemented elderly individuals.
Progress in clinical and biological research 1989;317():1001-5.
1988: Fabrizio Tagliavini; Giorgio Giaccone; Blas Frangione; Orso Bugiani
Preamyloid deposits in the cerebral cortex of patients with Alzheimer's disease and nondemented individuals.
Neuroscience letters 1988;93(2-3):191-6.
1988: Giorgio Giaccone; Fabrizio Tagliavini; J S Street; Bernardino Ghetti; Orso Bugiani
Progressive supranuclear palsy with hypertrophy of the olives. An immunocytochemical study of the cytoskeleton of argyrophilic neurons.
Acta neuropathologica 1988;77(1):14-20.