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Towia Libermann

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Arkaitz Carracedo; Vincent C J de Boer; Ainara Egia; Lydia S Finley; Zachary Gerhart-Hines; Marcia C Haigis; Keisuke Ito; Gaelle Laurent; Amy K Leliaert; Towia Libermann; Elefteria Maratos-Flier; Pere Puigserver; Andrea L Richardson; Zachary T Schafer; Su Jung Song; Maria Sundvall; Dror Weiss; Andrew C Adams; Manoj Bhasin; Pier P Pandolfi
A metabolic prosurvival role for PML in breast cancer.
Liang Zhang; Manoj Bhasin; Rachel Schor-Bardach; Xiaoen Wang; Michael P Collins; David Panka; Prabhakar Putheti; Sabina Signoretti; David C Alsop; Towia Libermann; Michael B Atkins; James W Mier; S Nahum Goldberg; Rupal S Bhatt
Resistance of renal cell carcinoma to sorafenib is mediated by potentially reversible gene expression.
Manoj Bhasin; Lei Yuan; Derin B Keskin; Hasan H Otu; Towia Libermann; Peter Oettgen
Bioinformatic identification and characterization of human endothelial cell-restricted genes.

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All Publications

2012: Arkaitz Carracedo; Vincent C J de Boer; Ainara Egia; Lydia S Finley; Zachary Gerhart-Hines; Marcia C Haigis; Keisuke Ito; Gaelle Laurent; Amy K Leliaert; Towia Libermann; Elefteria Maratos-Flier; Pere Puigserver; Andrea L Richardson; Zachary T Schafer; Su Jung Song; Maria Sundvall; Dror Weiss; Andrew C Adams; Manoj Bhasin; Pier P Pandolfi
A metabolic prosurvival role for PML in breast cancer.
The Journal of clinical investigation 2012;122(9):3088-100.
2011: Liang Zhang; Manoj Bhasin; Rachel Schor-Bardach; Xiaoen Wang; Michael P Collins; David Panka; Prabhakar Putheti; Sabina Signoretti; David C Alsop; Towia Libermann; Michael B Atkins; James W Mier; S Nahum Goldberg; Rupal S Bhatt
Resistance of renal cell carcinoma to sorafenib is mediated by potentially reversible gene expression.
PloS one 2011;6(4):e19144.
2010: Manoj Bhasin; Lei Yuan; Derin B Keskin; Hasan H Otu; Towia Libermann; Peter Oettgen
Bioinformatic identification and characterization of human endothelial cell-restricted genes.
BMC genomics 2010;11():342.
2009: Wolf C Prall; Akos Czibere; Franck Grall; Dimitrios Spentzos; Ulrich Steidl; Aristoteles Giagounidis; Andrea Kuendgen; Hasan Otu; Astrid Rong; Towia Libermann; Ulrich Germing; Norbert Gattermann; Rainer Haas; Manuel Aivado
Differential gene expression of bone marrow-derived CD34+ cells is associated with survival of patients suffering from myelodysplastic syndrome.
International journal of hematology 2009;89(2):173-87.
2008: Maria Koulmanda; Manoj Bhasin; Lauren Hoffman; Zhigang Fan; Andi Qipo; Hang Shi; Susan Bonner-Weir; Prabhakar Putheti; Nicolas Degauque; Towia Libermann; Hugh Auchincloss; Jeffrey S Flier; Terry B Strom
Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(42):16242-7.
2008: Kerstyn M Haram; Heidi J Peltier; Bin Lu; Manoj Bhasin; Hasan H Otu; Bob Choy; Meredith Regan; Towia Libermann; Gary J Latham; Martin G Sanda; M Simo Arredouani
Gene expression profile of mouse prostate tumors reveals dysregulations in major biological processes and identifies potential murine targets for preclinical development of human prostate cancer therapy.
The Prostate 2008;68(14):1517-30.
2008: Kosei Ijiri; Luiz F Zerbini; Haibing Peng; Hasan H Otu; Kaneyuki Tsuchimochi; Miguel Otero; Cecilia Dragomir; Nicole Walsh; Benjamin E Bierbaum; David Mattingly; Geoff van Flandern; Setsuro Komiya; Thomas Aigner; Towia Libermann; Mary B Goldring
Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.
Arthritis and rheumatism 2008;58(7):2075-87.
2008: Sabina Signoretti; Gennady Bratslavsky; Frederick M Waldman; Victor E Reuter; John Haaga; Maria Merino; George V Thomas; Michael R Pins; Towia Libermann; John Gillespie; Joseph E Tomaszewski; Carolyn Corlies Compton; Andrew Hruszkewycz; W Marston Linehan; Michael B Atkins
Tissue-based research in kidney cancer: current challenges and future directions.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(12):3699-705.
2008: Haibing Peng; Lujian Tan; Makoto Osaki; Yumei Zhan; Kosei Ijiri; Kaneyuki Tsuchimochi; Miguel Otero; Hong Wang; Bob K Choy; Franck Grall; Xuesong Gu; Towia Libermann; Peter Oettgen; Mary B Goldring
ESE-1 is a potent repressor of type II collagen gene (COL2A1) transcription in human chondrocytes.
Journal of cellular physiology 2008;215(2):562-73.
2008: Lorella Marselli; Jeffrey Thorne; Yu-Bae Ahn; Abdulkadir Omer; Dennis C Sgroi; Towia Libermann; Hasan H Otu; Arun Sharma; Susan Bonner-Weir; Gordon C Weir
Gene expression of purified beta-cell tissue obtained from human pancreas with laser capture microdissection.
The Journal of clinical endocrinology and metabolism 2008;93(3):1046-53.
2008: Bárbara Rücker; Manoela E Almeida; Towia Libermann; Luiz F Zerbini; Márcia R Wink; João José Freitas Sarkis
E-NTPDases and ecto-5'-nucleotidase expression profile in rat heart left ventricle and the extracellular nucleotide hydrolysis by their nerve terminal endings.
Life sciences 2008;82(9-10):477-86.
2008: Jon Jones; Hasan H Otu; Franck Grall; Dimitrios Spentzos; Handan Can; Manuel Aivado; Arie S Belldegrun; Allan J Pantuck; Towia Libermann
Proteomic identification of interleukin-2 therapy response in metastatic renal cell cancer.
The Journal of urology 2008;179(2):730-6.
2008: Noah T Zinkin; Franck Grall; Killimangalam Bhaskar; Hasan H Otu; Dimitrios Spentzos; Brett Kalmowitz; Meghan Wells; Manuel Guerrero; John M Asara; Towia Libermann; Nezam H Afdhal
Serum proteomics and biomarkers in hepatocellular carcinoma and chronic liver disease.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(2):470-7.
2008: Jeffery A Dusek; Hasan H Otu; Ann L Wohlhueter; Manoj Bhasin; Luiz F Zerbini; Marie G Joseph; Herbert Benson; Towia Libermann
Genomic counter-stress changes induced by the relaxation response.
PloS one 2008;3(7):e2576.
2008: Vesna Nikolova-Krstevski; Manoj Bhasin; Hasan H Otu; Towia Libermann; Peter Oettgen
Gene expression analysis of embryonic stem cells expressing VE-cadherin (CD144) during endothelial differentiation.
BMC genomics 2008;9():240.
2007: Bárbara Rücker; Manoela E Almeida; Towia Libermann; Luiz F Zerbini; Márcia R Wink; João José Freitas Sarkis
Biochemical characterization of ecto-nucleotide pyrophosphatase/phosphodiesterase (E-NPP, E.C. 3.1.4.1) from rat heart left ventricle.
Molecular and cellular biochemistry 2007;306(1-2):247-54.
2007: Xiaoping Zhang; Liang Zhang; Hongmei Yang; Xu Huang; Hasan H Otu; Towia Libermann; William C DeWolf; Roya Khosravi-Far; Aria F Olumi
c-Fos as a proapoptotic agent in TRAIL-induced apoptosis in prostate cancer cells.
Cancer research 2007;67(19):9425-34.
2007: Basel Ramlawi; Hasan H Otu; James L Rudolph; Shigetoshi Mieno; Isaac S Kohane; Handan Can; Towia Libermann; Edward R Marcantonio; Cesario Bianchi; Frank W Sellke
Genomic expression pathways associated with brain injury after cardiopulmonary bypass.
The Journal of thoracic and cardiovascular surgery 2007;134(4):996-1005.
2007: Dimitrios Spentzos; Stephen A Cannistra; Franck Grall; Douglas A Levine; Kamana Pillay; Towia Libermann; Christos S Mantzoros
IGF axis gene expression patterns are prognostic of survival in epithelial ovarian cancer.
Endocrine-related cancer 2007;14(3):781-90.
2007: Wolf C Prall; Akos Czibere; Marcus Jäger; Dimitrios Spentzos; Towia Libermann; Norbert Gattermann; Rainer Haas; Manuel Aivado
Age-related transcription levels of KU70, MGST1 and BIK in CD34+ hematopoietic stem and progenitor cells.
Mechanisms of ageing and development 2007;128(9):503-10.
2007: KyungWon Huh; Xiaobo Zhou; Hiroyuki Hayakawa; Je-Yoel Cho; Towia Libermann; Jianping Jin; J Wade Harper; Karl Munger
Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor.
Journal of virology 2007;81(18):9737-47.
2007: Andréia Buffon; Emerson André Casali; Towia Libermann; B V Ribeiro; S C Robson; Márcia R Wink; Luiz F Zerbini; João José Freitas Sarkis
NTPDase and 5' ecto-nucleotidase expression profiles and the pattern of extracellular ATP metabolism in the Walker 256 tumor.
Biochimica et biophysica acta 2007;1770(8):1259-65.
2007: Adam R Kennedy; Pavlos Pissios; Hasan H Otu; Russell Roberson; Bingzhong Xue; Kenji Asakura; Noburu Furukawa; Frank E Marino; Fen-Fen Liu; Barbara B Kahn; Towia Libermann; Eleftheria Maratos-Flier
A high-fat, ketogenic diet induces a unique metabolic state in mice.
American journal of physiology. Endocrinology and metabolism 2007;292(6):E1724-39.
2007: Xuesong Gu; Luiz F Zerbini; Hasan H Otu; Manoj Bhasin; Quanli Yang; Marie G Joseph; Franck Grall; Tomi Onatunde; Ricardo G Correa; Towia Libermann
Reduced PDEF expression increases invasion and expression of mesenchymal genes in prostate cancer cells.
Cancer research 2007;67(9):4219-26.
2007: Hasan H Otu; Kamila Naxerova; Karen Ho; Handan Can; Nicole Nesbitt; Towia Libermann; Seth J Karp
Restoration of liver mass after injury requires proliferative and not embryonic transcriptional patterns.
The Journal of biological chemistry 2007;282(15):11197-204.
2007: Yulia Gnainsky; Z Kushnirsky; G Bilu; Y Hagai; Olga Genina; Hanne Volpin; Rafael Bruck; Gadi Spira; Arnon Nagler; N Kawada; Katsutoshi Yoshizato; D P Reinhardt; Towia Libermann; Mark Pines
Gene expression during chemically induced liver fibrosis: effect of halofuginone on TGF-beta signaling.
Cell and tissue research 2007;328(1):153-66.
2007: Hasan H Otu; Handan Can; Dimitrios Spentzos; Robert G Nelson; Robert L Hanson; Helen C Looker; William C Knowler; Manuel Monroy; Towia Libermann; S Ananth Karumanchi; Ravi Thadhani
Prediction of diabetic nephropathy using urine proteomic profiling 10 years prior to development of nephropathy.
Diabetes care 2007;30(3):638-43.
2007: Manuel Aivado; Dimitrios Spentzos; Ulrich Germing; Gil Alterovitz; Xiao-Ying Meng; Franck Grall; Aristoteles Giagounidis; Giannoula Klement; Ulrich Steidl; Hasan H Otu; Akos Czibere; Wolf C Prall; Christof Iking-Konert; Michelle Shayne; Marco F Ramoni; Norbert Gattermann; Rainer Haas; Constantine S Mitsiades; Eric T Fung; Towia Libermann
Serum proteome profiling detects myelodysplastic syndromes and identifies CXC chemokine ligands 4 and 7 as markers for advanced disease.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(4):1307-12.
2007: Jon Jones; Towia Libermann
Genomics of renal cell cancer: the biology behind and the therapy ahead.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(2 Pt 2):685s-692s.
2007: Michael B Atkins; Marc S Ernstoff; Robert A Figlin; Keith T Flaherty; Daniel J George; William G Kaelin; Eugene D Kwon; Towia Libermann; W Marston Linehan; David F McDermott; Augusto C Ochoa; Allan J Pantuck; Brian I Rini; Mark A Rosen; Jeffrey A Sosman; Vikas P Sukhatme; Johannes W Vieweg; Christopher G Wood; Laura King
Innovations and challenges in renal cell carcinoma: summary statement from the Second Cambridge Conference.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(2 Pt 2):667s-670s.
2006: Luiz F Zerbini; Akos Czibere; Yihong Wang; Ricardo G Correa; Hasan H Otu; Marie Joseph; Yuko Takayasu; Moriah Silver; Xuesong Gu; Kriangsak Ruchusatsawat; Linglin Li; Devanand Sarkar; Jin-Rong Zhou; Paul B Fisher; Towia Libermann
A novel pathway involving melanoma differentiation associated gene-7/interleukin-24 mediates nonsteroidal anti-inflammatory drug-induced apoptosis and growth arrest of cancer cells.
Cancer research 2006;66(24):11922-31.
2006: Ulrich Steidl; Frank Rosenbauer; Roel G W Verhaak; Xuesong Gu; Alexander Ebralidze; Hasan H Otu; Steffen Klippel; Christian Steidl; Ingmar Bruns; Daniel B Costa; Katharina Wagner; Manuel Aivado; Guido Kobbe; Peter J M Valk; Emmanuelle Passegué; Towia Libermann; Ruud Delwel; Daniel G Tenen
Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells.
Nature genetics 2006;38(11):1269-77.
2006: Akos Czibere; Wolf C Prall; Luiz F Zerbini; Markus Jäger; Guido Kobbe; Sabine Knipp; Towia Libermann; Rainer Haas; Manuel Aivado
Exisulind induces apoptosis in advanced myelodysplastic syndrome (MDS) and acute myeloid leukaemia/MDS.
British journal of haematology 2006;135(3):355-7.
2006: Mona Khurana; Avram Z Traum; Manuel Aivado; Meghan P Wells; Manuel Guerrero; Franck Grall; Towia Libermann; Asher D Schachter
Urine proteomic profiling of pediatric nephrotic syndrome.
Pediatric nephrology (Berlin, Germany) 2006;21(9):1257-65.
2006: Basset El Essawy; Hasan H Otu; Bob K Choy; Xin Xiao Zheng; Towia Libermann; Terry B Strom
Proteomic analysis of the allograft response.
Transplantation 2006;82(2):267-74.
2006: Shivalingappa Venkatesha; Mourad Toporsian; Chun Lam; Jun-ichi Hanai; Tadanori Mammoto; Yeon M Kim; Yuval Bdolah; Kee-Hak Lim; Hai-Tao Yuan; Towia Libermann; Isaac E Stillman; Drucilla Roberts; Patricia A D'Amore; Franklin H Epstein; Frank W Sellke; Roberto Romero; Vikas P Sukhatme; Michelle Letarte; S Ananth Karumanchi
Soluble endoglin contributes to the pathogenesis of preeclampsia.
Nature medicine 2006;12(6):642-9.
2006: Avram Z Traum; Meghan P Wells; Manuel Aivado; Towia Libermann; Marco F Ramoni; Asher D Schachter
SELDI-TOF MS of quadruplicate urine and serum samples to evaluate changes related to storage conditions.
Proteomics 2006;6(5):1676-80.
2006: Towia Libermann; Luiz F Zerbini
Targeting transcription factors for cancer gene therapy.
Current gene therapy 2006;6(1):17-33.
2006: Constantine S Mitsiades; Nicholas Mitsiades; Ciaran McMullan; Vassiliki Poulaki; Andrew L Kung; Faith E Davies; Gareth Morgan; Masaharu Akiyama; Reshma Shringarpure; Nikhil C Munshi; Paul G Richardson; Teru Hideshima; Dharminder Chauhan; Xuesong Gu; Charles Bailey; Marie Joseph; Towia Libermann; Neal Rosen; Kenneth C Anderson
Antimyeloma activity of heat shock protein-90 inhibition.
Blood 2006;107(3):1092-100.
2006: Deepti B Ramnarain; Seongmi Park; Diana Y Lee; Kimmo J Hatanpaa; Shane O Scoggin; Hasan H Otu; Towia Libermann; Jack Raisanen; Raheela Ashfaq; Eric T Wong; Julian Wu; Robert Elliott; Amyn A Habib
Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells.
Cancer research 2006;66(2):867-74.
2006: Márcia R Wink; Elizandra Braganhol; Alessandra S K Tamajusuku; Guido Lenz; Luiz F Zerbini; Towia Libermann; Jean Sévigny; Ana Maria Oliveira Battastini; S C Robson
Nucleoside triphosphate diphosphohydrolase-2 (NTPDase2/CD39L1) is the dominant ectonucleotidase expressed by rat astrocytes.
Neuroscience 2006;138(2):421-32.
2005: Kosei Ijiri; Luiz F Zerbini; Haibing Peng; Ricardo G Correa; Binfeng Lu; Nicole Walsh; Yani Zhao; Noboru Taniguchi; Xu-Ling Huang; Hasan H Otu; Hong Wang; Jian Fei Wang; Setsuro Komiya; Patricia Ducy; Mahboob U Rahman; Richard A Flavell; Ellen M Gravallese; Peter Oettgen; Towia Libermann; Mary B Goldring
A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation.
The Journal of biological chemistry 2005;280(46):38544-55.
2005: Dimitrios Spentzos; Douglas A Levine; Shakirahmed Kolia; Hasan H Otu; Jeff Boyd; Towia Libermann; Stephen A Cannistra
Unique gene expression profile based on pathologic response in epithelial ovarian cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(31):7911-8.
2005: Youichiro Wada; Hasan H Otu; Shengqian Wu; Md Ruhul Abid; Hitomi Okada; Towia Libermann; Tatsuhiko Kodama; Shu-Ching Shih; Takashi Minami; William C Aird
Preconditioning of primary human endothelial cells with inflammatory mediators alters the "set point" of the cell.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(13):1914-6.
2005: Luiz F Zerbini; Towia Libermann
GADD45 deregulation in cancer: frequently methylated tumor suppressors and potential therapeutic targets.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(18):6409-13.
2005: Luiz F Zerbini; Yihong Wang; Ricardo G Correa; Je-Yoel Cho; Towia Libermann
Blockage of NF-kappaB induces serine 15 phosphorylation of mutant p53 by JNK kinase in prostate cancer cells.
Cell cycle (Georgetown, Tex.) 2005;4(9):1247-53.
2005: Jon Jones; Hasan H Otu; Dimitrios Spentzos; Shakirahmed Kolia; Mehmet Inan; Wolf-Dietrich Beecken; Christian Fellbaum; Xuesong Gu; Marie Joseph; Allan J Pantuck; Dietger Jonas; Towia Libermann
Gene signatures of progression and metastasis in renal cell cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(16):5730-9.
2005: Akos Czibere; Wolf C Prall; Luiz F Zerbini; Franck Grall; Eve C Craigie; Slif D Ulrich; Aristoteles Giagounidis; Rainer Haas; Towia Libermann; Manuel Aivado
The nonsteroidal anti-inflammatory drug Exisulind selectively induces apoptosis via JNK in secondary acute myeloid leukemia after myelodysplastic syndrome.
Cell cycle (Georgetown, Tex.) 2005;4(6):812-7.
2005: Antonio Mazzocca; Roberto Coppari; Raffaella De Franco; Je-Yoel Cho; Towia Libermann; Massimo Pinzani; Alex Toker
A secreted form of ADAM9 promotes carcinoma invasion through tumor-stromal interactions.
Cancer research 2005;65(11):4728-38.
2005: Franck T Grall; Wolf C Prall; Wanjiang Wei; Xuesong Gu; Je-Yoel Cho; Bob K Choy; Luiz F Zerbini; Mehmet S Inan; Steven R Goldring; Ellen M Gravallese; Mary B Goldring; Peter Oettgen; Towia Libermann
The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes.
The FEBS journal 2005;272(7):1676-87.
2005: Manuel Aivado; Dimitrios Spentzos; Gil Alterovitz; Hasan H Otu; Franck Grall; Aristoteles Giagounidis; Meghan Wells; Je-Yoel Cho; Ulrich Germing; Akos Czibere; Wolf C Prall; Chris Porter; Marco F Ramoni; Towia Libermann
Optimization and evaluation of surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) with reversed-phase protein arrays for protein profiling.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2005;43(2):133-40.
2005: Luiz F Zerbini; Towia Libermann
Life and death in cancer. GADD45 alpha and gamma are critical regulators of NF-kappaB mediated escape from programmed cell death.
Cell cycle (Georgetown, Tex.) 2005;4(1):18-20.
2004: Dimitrios Spentzos; Douglas A Levine; Marco F Ramoni; Marie Joseph; Xuesong Gu; Jeff Boyd; Towia Libermann; Stephen A Cannistra
Gene expression signature with independent prognostic significance in epithelial ovarian cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(23):4700-10.
2004: Dietrich von Stechow; D Zurakowski; Allison R Pettit; R Müller; Gloria A Gronowicz; Michael Chorev; Hasan H Otu; Towia Libermann; Joseph M Alexander
Differential transcriptional effects of PTH and estrogen during anabolic bone formation.
Journal of cellular biochemistry 2004;93(3):476-90.
2004: Pierre Voisine; Marc Ruel; Tanveer A Khan; Cesario Bianchi; Shu-Hua Xu; Isaac S Kohane; Towia Libermann; Hasan H Otu; Alan Saltiel; Frank W Sellke
Differences in gene expression profiles of diabetic and nondiabetic patients undergoing cardiopulmonary bypass and cardioplegic arrest.
Circulation 2004;110(11 Suppl 1):II280-6.
2004: Luiz F Zerbini; Yihong Wang; Akos Czibere; Ricardo G Correa; Je-Yoel Cho; Kosei Ijiri; Wanjang Wei; Marie Joseph; Xuesong Gu; Franck Grall; Mary B Goldring; Jin-Rong Zhou; Towia Libermann; Jin-Rhong Zhou
NF-kappa B-mediated repression of growth arrest- and DNA-damage-inducible proteins 45alpha and gamma is essential for cancer cell survival.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(37):13618-23.
2004: Jin-Rong Zhou; Lunyin Yu; Luiz F Zerbini; Towia Libermann; George L Blackburn
Progression to androgen-independent LNCaP human prostate tumors: cellular and molecular alterations.
International journal of cancer. Journal international du cancer 2004;110(6):800-6.
2004: Young Kwon Hong; Kimberly E Foreman; Jay W Shin; Satoshi Hirakawa; Christine L Curry; David R Sage; Towia Libermann; Bruce J Dezube; Joyce Diane Fingeroth; Michael Detmar
Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus.
Nature genetics 2004;36(7):683-5.
2004: Hong Wang; Ruihua Fang; Je-Yoel Cho; Towia Libermann; Peter Oettgen
Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86.
The Journal of biological chemistry 2004;279(24):25241-50.
2004: Je-Yoel Cho; Yasmin Akbarali; Luiz F Zerbini; Xuesong Gu; Jay Boltax; Yihong Wang; Peter Oettgen; Dong-Er Zhang; Towia Libermann
Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene.
The Journal of biological chemistry 2004;279(19):19512-22.
2004: Courtney Brown; John Gaspar; Allison R Pettit; Rebecca Lee; Xuesong Gu; Hong Wang; Cathy Manning; Carole Voland; Steven R Goldring; Mary B Goldring; Towia Libermann; Ellen M Gravallese; Peter Oettgen
ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation.
The Journal of biological chemistry 2004;279(13):12794-803.
2004: Constantine S Mitsiades; Nicholas Mitsiades; Ciaran McMullan; Vassiliki Poulaki; Reshma Shringarpure; Masaharu Akiyama; Teru Hideshima; Dharminder Chauhan; Marie Joseph; Towia Libermann; Carlos García-Echeverría; Mark A Pearson; Francesco Hofmann; Kenneth C Anderson; Andrew L Kung
Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors.
Cancer cell 2004;5(3):221-30.
2004: Constantine S Mitsiades; Nicholas Mitsiades; Ciaran McMullan; Vassiliki Poulaki; Reshma Shringarpure; Teru Hideshima; Masaharu Akiyama; Dharminder Chauhan; Nikhil C Munshi; Xuesong Gu; Charles Bailey; Marie Joseph; Towia Libermann; Victoria M Richon; Paul A Marks; Kenneth C Anderson
Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):540-5.
2004: Gil Alterovitz; Manuel Aivado; Dimitrios Spentzos; Towia Libermann; Marco F Ramoni; Isaac S Kohane
Analysis and robot pipelined automation for SELDI-TOF mass spectrometry.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2004;4():3068-71.
2003: Marc Ruel; Cesario Bianchi; Tanveer A Khan; Shu Xu; John R Liddicoat; Pierre Voisine; Eugenio G Araujo; Helen Lyon; Isaac S Kohane; Towia Libermann; Frank W Sellke
Gene expression profile after cardiopulmonary bypass and cardioplegic arrest.
The Journal of thoracic and cardiovascular surgery 2003;126(5):1521-30.
2003: Nicolas O Fortunel; Hasan H Otu; Huck-Hui Ng; Jinhui Chen; Xiuqian Mu; Timothy Chevassut; Xiaoyu Li; Marie Joseph; Charles Bailey; Jacques A Hatzfeld; Antoinette Hatzfeld; Fatih Usta; Vinsensius B Vega; Philip M Long; Towia Libermann; Bing Lim
Comment on " 'Stemness': transcriptional profiling of embryonic and adult stem cells" and "a stem cell molecular signature".
Science (New York, N.Y.) 2003;302(5644):393; author reply 393.
2003: Franck Grall; Xuesong Gu; Lujian Tan; Je-Yoel Cho; Mehmet Sait Inan; Allison R Pettit; Usanee Thamrongsak; Bob K Choy; Cathy Manning; Yasmin Akbarali; Luiz F Zerbini; Susan Rudders; Steven R Goldring; Ellen M Gravallese; Peter Oettgen; Mary B Goldring; Towia Libermann
Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappaB-mediated induction of the Ets transcription factor ESE-1.
Arthritis and rheumatism 2003;48(5):1249-60.
2003: Luiz F Zerbini; Yihong Wang; Je-Yoel Cho; Towia Libermann
Constitutive activation of nuclear factor kappaB p50/p65 and Fra-1 and JunD is essential for deregulated interleukin 6 expression in prostate cancer.
Cancer research 2003;63(9):2206-15.
2003: Nicholas Mitsiades; Constantine S Mitsiades; Paul G Richardson; Vassiliki Poulaki; Yu-Tzu Tai; Dharminder Chauhan; Galinos Fanourakis; Xuesong Gu; Charles Bailey; Marie Joseph; Towia Libermann; Robert Schlossman; Nikhil C Munshi; Teru Hideshima; Kenneth C Anderson
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications.
Blood 2003;101(6):2377-80.
2003: Sharon E Maynard; Jiang-Yong Min; Jaime Merchan; Kee-Hak Lim; Jianyi Li; Susanta Mondal; Towia Libermann; James P Morgan; Frank W Sellke; Isaac E Stillman; Franklin H Epstein; Vikas P Sukhatme; S Ananth Karumanchi
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia.
The Journal of clinical investigation 2003;111(5):649-58.
2003: Satoshi Hirakawa; Young Kwon Hong; Natasha Harvey; Vivien Schacht; Kant Matsuda; Towia Libermann; Michael Detmar
Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells.
The American journal of pathology 2003;162(2):575-86.
2003: JOHN KWON; Sarah Keates; Simos Simeonidis; Franck Grall; Towia Libermann; Andrew C Keates
ESE-1, an enterocyte-specific Ets transcription factor, regulates MIP-3alpha gene expression in Caco-2 human colonic epithelial cells.
The Journal of biological chemistry 2003;278(2):875-84.
2002: Eric S Silverman; Rebecca M Baron; Lyle Palmer; Louis Le; Arlene Hallock; Venkat Subramaniam; Richard J Riese; Matthew D McKenna; Xuesong Gu; Towia Libermann; Antonio Tugores; Kathleen J Haley; Stephanie Shore; Jeffrey M Drazen; Scott Weiss
Constitutive and cytokine-induced expression of the ETS transcription factor ESE-3 in the lung.
American journal of respiratory cell and molecular biology 2002;27(6):697-704.
2002: Nicholas Mitsiades; Constantine S Mitsiades; Vassiliki Poulaki; Dharminder Chauhan; Galinos Fanourakis; Xuesong Gu; Charles Bailey; Marie Joseph; Towia Libermann; Steve P Treon; Nikhil C Munshi; Paul G Richardson; Teru Hideshima; Kenneth C Anderson
Molecular sequelae of proteasome inhibition in human multiple myeloma cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(22):14374-9.
2002: Alysson Renato Muotri; Maria C N Marchetto; Luiz F Zerbini; Towia Libermann; Armando Morais Ventura; Alain Sarasin; Carlos F M Menck
Complementation of the DNA repair deficiency in human xeroderma pigmentosum group a and C cells by recombinant adenovirus-mediated gene transfer.
Human gene therapy 2002;13(15):1833-44.
2002: Rebecca M Baron; Lyle Palmer; Kelan G Tantisira; Stacey Gabriel; Larry A Sonna; Louis Le; Arlene Hallock; Towia Libermann; Jeffrey M Drazen; Scott Weiss; Eric S Silverman
DNA sequence variants in epithelium-specific ETS-2 and ETS-3 are not associated with asthma.
American journal of respiratory and critical care medicine 2002;166(7):927-32.
2002: Luiz F Zerbini; Towia Libermann; Armando Morais Ventura
Insertion of an exogenous domain in the adenovirus type 2 fiber globular region.
Biochemical and biophysical research communications 2002;296(4):897-903.
2002: John Gaspar; Shelley N-M Thai; Carole Voland; Antoinise Dube; Towia Libermann; M Luisa Iruela-Arispe; Peter Oettgen
Opposing functions of the Ets factors NERF and ELF-1 during chicken blood vessel development.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(7):1106-12.
2002: Gloria P Bowen; Stephanie L Borgland; Mindy Lam; Towia Libermann; Norman C W Wong; Daniel A Muruve
Adenovirus vector-induced inflammation: capsid-dependent induction of the C-C chemokine RANTES requires NF-kappa B.
Human gene therapy 2002;13(3):367-79.
2002: CL Tsien; Towia Libermann; X Gu; A Kho; I S Kohane
CHIP TUNER: a web tool for evidence-based noise reduction in gene discovery.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2002;():810-4.
2001: M D'Addario; Towia Libermann; Jingwu Xu; Ali Ahmad; José Menezes
Epstein-Barr Virus and its glycoprotein-350 upregulate IL-6 in human B-lymphocytes via CD21, involving activation of NF-kappaB and different signaling pathways.
Journal of molecular biology 2001;308(3):501-14.
2001: Xuesong Gu; B H Shin; Yasmin Akbarali; A Weiss; Jay Boltax; Peter Oettgen; Towia Libermann
Tel-2 is a novel transcriptional repressor related to the Ets factor Tel/ETV-6.
The Journal of biological chemistry 2001;276(12):9421-36.
2001: Antoinise Dube; Shelley N-M Thai; John Gaspar; Susan Rudders; Towia Libermann; L Iruela-Arispe; Peter Oettgen
Elf-1 is a transcriptional regulator of the Tie2 gene during vascular development.
Circulation research 2001;88(2):237-44.
2001: Susan Rudders; John Gaspar; Rebecca Madore; Carole Voland; Franck Grall; Manoj Patel; A Pellacani; Mark A Perrella; Towia Libermann; Peter Oettgen
ESE-1 is a novel transcriptional mediator of inflammation that interacts with NF-kappa B to regulate the inducible nitric-oxide synthase gene.
The Journal of biological chemistry 2001;276(5):3302-9.
2001: CL Tsien; Towia Libermann; X Gu; I S Kohane
On reporting fold differences.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2001;():496-507.
2000: Stephanie L Borgland; Gloria P Bowen; Norman C W Wong; Towia Libermann; Daniel A Muruve
Adenovirus vector-induced expression of the C-X-C chemokine IP-10 is mediated through capsid-dependent activation of NF-kappaB.
Journal of virology 2000;74(9):3941-7.
2000: Felix H Brembeck; Oliver G Opitz; Towia Libermann; Anil K Rustgi
Dual function of the epithelial specific ets transcription factor, ELF3, in modulating differentiation.
Oncogene 2000;19(15):1941-9.
2000: K Kas; E Finger; Franck Grall; Xuesong Gu; Yasmin Akbarali; Jay Boltax; A Weiss; Peter Oettgen; R Kapeller; Towia Libermann
ESE-3, a novel member of an epithelium-specific ets transcription factor subfamily, demonstrates different target gene specificity from ESE-1.
The Journal of biological chemistry 2000;275(4):2986-98.
2000: Peter Oettgen; E Finger; Z Sun; Yasmin Akbarali; Usanee Thamrongsak; Jay Boltax; Franck Grall; Antoinise Dube; A Weiss; L Brown; G Quinn; K Kas; G Endress; C Kunsch; Towia Libermann
PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression.
The Journal of biological chemistry 2000;275(2):1216-25.
1999: Peter Oettgen; K Kas; Antoinise Dube; Xuesong Gu; Franck Grall; Usanee Thamrongsak; Yasmin Akbarali; E Finger; Jay Boltax; G Endress; K Munger; C Kunsch; Towia Libermann
Characterization of ESE-2, a novel ESE-1-related Ets transcription factor that is restricted to glandular epithelium and differentiated keratinocytes.
The Journal of biological chemistry 1999;274(41):29439-52.
1999: Markus Schwaninger; S Sallmann; N Petersen; Armin Schneider; Simone Prinz; Towia Libermann; Matthias Spranger
Bradykinin induces interleukin-6 expression in astrocytes through activation of nuclear factor-kappaB.
Journal of neurochemistry 1999;73(4):1461-6.
1999: Towia Libermann; Z Pan; Yasmin Akbarali; Christopher J Hetherington; Jay Boltax; DA Yergeau; Dong-Er Zhang
AML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoter.
The Journal of biological chemistry 1999;274(35):24671-6.
1999: Antoinise Dube; Yasmin Akbarali; T N Sato; Towia Libermann; Peter Oettgen
Role of the Ets transcription factors in the regulation of the vascular-specific Tie2 gene.
Circulation research 1999;84(10):1177-85.
1999: Daniel A Muruve; M J Barnes; Isaac E Stillman; Towia Libermann
Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo.
Human gene therapy 1999;10(6):965-76.
1999: Peter Oettgen; MA Barcinski; Jay Boltax; P Stolt; Yasmin Akbarali; Towia Libermann
Genomic organization of the human ELF3 (ESE-1/ESX) gene, a member of the Ets transcription factor family, and identification of a functional promoter.
Genomics 1999;55(3):358-62.
1998: Madhu Gupta; R Zak; Towia Libermann; Mahesh P Gupta
Tissue-restricted expression of the cardiac alpha-myosin heavy chain gene is controlled by a downstream repressor element containing a palindrome of two ets-binding sites.
Molecular and cellular biology 1998;18(12):7243-58.
1998: Daniel Goldman; MK Sapru; Scott Stewart; J Plotkin; Towia Libermann; B Wasylyk; Kunliang Guan
Cloning and characterization of GETS-1, a goldfish Ets family member that functions as a transcriptional repressor in muscle.
The Biochemical journal 1998;335 ( Pt 2)():267-75.
1998: M Sata; H Perlman; Daniel A Muruve; Marcy Silver; M Ikebe; Towia Libermann; Peter Oettgen; Kenneth Walsh
Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(3):1213-7.
1997: Jude E Onyia; Towia Libermann; J Bidwell; D Arnold; Y Tu; P McClelland; Janet Hock
Parathyroid hormone (1-34)-mediated interleukin-6 induction.
Journal of cellular biochemistry 1997;67(2):265-74.
1997: Peter Oettgen; KC Carter; Meena Augustus; MA Barcinski; Jay Boltax; C Kunsch; Towia Libermann
The novel epithelial-specific Ets transcription factor gene ESX maps to human chromosome 1q32.1.
Genomics 1997;45(2):456-7.
1997: Daniel A Muruve; R C Manfro; Terry B Strom; Towia Libermann
Ex vivo adenovirus-mediated gene delivery leads to long-term expression in pancreatic islet transplants.
Transplantation 1997;64(3):542-6.
1997: Peter Oettgen; Rhoda M Alani; MA Barcinski; L Brown; Yasmin Akbarali; Jay Boltax; C Kunsch; K Munger; Towia Libermann
Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family.
Molecular and cellular biology 1997;17(8):4419-33.
1997: Daniel A Muruve; A G Nicolson; R C Manfro; Terry B Strom; Vikas P Sukhatme; Towia Libermann
Adenovirus-mediated expression of Fas ligand induces hepatic apoptosis after Systemic administration and apoptosis of ex vivo-infected pancreatic islet allografts and isografts.
Human gene therapy 1997;8(8):955-63.
1996: Yasmin Akbarali; Peter Oettgen; Jay Boltax; Towia Libermann
ELF-1 interacts with and transactivates the IgH enhancer pi site.
The Journal of biological chemistry 1996;271(42):26007-12.
1996: Peter Oettgen; Yasmin Akbarali; Jay Boltax; J Best; C Kunsch; Towia Libermann
Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1.
Molecular and cellular biology 1996;16(9):5091-106.
1996: Dharminder Chauhan; H Uchiyama; Yasmin Akbarali; Mitsuyoshi Urashima; K Yamamoto; Towia Libermann; Kenneth C Anderson
Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa B.
Blood 1996;87(3):1104-12.
1994: U Dendorfer; Peter Oettgen; Towia Libermann
Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide.
Molecular and cellular biology 1994;14(7):4443-54.
1994: M Lopez; Peter Oettgen; Yasmin Akbarali; U Dendorfer; Towia Libermann
ERP, a new member of the ets transcription factor/oncoprotein family: cloning, characterization, and differential expression during B-lymphocyte development.
Molecular and cellular biology 1994;14(5):3292-309.
1994: T Lichtor; Towia Libermann
Coexpression of interleukin-1 beta and interleukin-6 in human brain tumors.
Neurosurgery 1994;34(4):669-72; discussion 672-3.
1993: Towia Libermann; David Baltimore
Pi, a pre-B-cell-specific enhancer element in the immunoglobulin heavy-chain enhancer.
Molecular and cellular biology 1993;13(10):5957-69.
1992: B L Rong; Towia Libermann; K Kogawa; S Ghosh; L X Cao; Deborah Pavan-Langston; E C Dunkel
HSV-1-inducible proteins bind to NF-kappa B-like sites in the HSV-1 genome.
Virology 1992;189(2):750-6.
1990: Towia Libermann; M Lenardo; David Baltimore
Involvement of a second lymphoid-specific enhancer element in the regulation of immunoglobulin heavy-chain gene expression.
Molecular and cellular biology 1990;10(6):3155-62.
1990: Towia Libermann; David Baltimore
Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.
Molecular and cellular biology 1990;10(5):2327-34.
1988: Monica Nistér; Towia Libermann; Christer Betsholtz; M Pettersson; Lena Claesson-Welsh; Carl-Henrik Heldin; J Schlessinger; Bengt Westermark
Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines.
Cancer research 1988;48(14):3910-8.
1987: Towia Libermann; R Friesel; Michael Jaye; R M Lyall; B Westermark; W Drohan; A Schmidt; Thomas Maciag; Joseph Schlessinger
An angiogenic growth factor is expressed in human glioma cells.
The EMBO journal 1987;6(6):1627-32.
1986: E Chen; L Coussens; Y C Liao; D Smith; T L Yang-Feng; J McGrath; C Van Beveren; Inder M Verma; Towia Libermann; J Schlessinger
Structural features of growth factor receptors with oncogenic potential.
Biochemical Society symposium 1986;52():65-82.
1985: L Coussens; T L Yang-Feng; Y C Liao; E Chen; A Gray; J McGrath; P H Seeburg; Towia Libermann; J Schlessinger; U Francke
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene.
Science (New York, N.Y.) 1985;230(4730):1132-9.
1985: Towia Libermann; H R Nusbaum; N Razon; R Kris; I Lax; H Soreq; N Whittle; M D Waterfield; A Ullrich; J Schlessinger
Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin.
Nature 1985;313(5998):144-7.
1985: Towia Libermann; H R Nusbaum; N Razon; R Kris; I Lax; H Soreq; N Whittle; M D Waterfield; A Ullrich; J Schlessinger
Amplification and overexpression of the EGF receptor gene in primary human glioblastomas.
Journal of cell science. Supplement 1985;3():161-72.
1985: H C Gooi; E F Hounsell; I Lax; R M Kris; Towia Libermann; J Schlessinger; J D Sato; T Kawamoto; J Mendelsohn; T Feizi
The carbohydrate specificities of the monoclonal antibodies 29.1, 455 and 3C1B12 to the epidermal growth factor receptor of A431 cells.
Bioscience reports 1985;5(1):83-94.
1984: I Lax; M Bar-Eli; Y Yarden; Towia Libermann; J Schlessinger
Antibodies to two defined regions of the transforming protein pp60src interact specifically with the epidermal growth factor receptor kinase system.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(19):5911-5.
1984: A Ullrich; L Coussens; J S Hayflick; T J Dull; A Gray; A W Tam; J Lee; Y Yarden; Towia Libermann; J Schlessinger
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells.
Nature 1984;309(5967):418-25.
1984: Towia Libermann; N Razon; A D Bartal; Y Yarden; J Schlessinger; H Soreq
Expression of epidermal growth factor receptors in human brain tumors.
Cancer research 1984;44(2):753-60.
1983: H C Gooi; J Schlessinger; I Lax; Y Yarden; Towia Libermann; T Feizi
Monoclonal antibody reactive with the human epidermal-growth-factor receptor recognizes the blood-group-A antigen.
Bioscience reports 1983;3(11):1045-52.
1983: J Hapgood; Towia Libermann; I Lax; Y Yarden; A B Schreiber; Z Naor; J Schlessinger
Monoclonal antibodies against epidermal growth factor receptor induce prolactin synthesis in cultured rat pituitary cells (GH3).
Proceedings of the National Academy of Sciences of the United States of America 1983;80(21):6451-5.
1983: A B Schreiber; Towia Libermann; I Lax; Y Yarden; J Schlessinger
Biological role of epidermal growth factor-receptor clustering. Investigation with monoclonal anti-receptor antibodies.
The Journal of biological chemistry 1983;258(2):846-53.
1983: J Schlessinger; A B Schreiber; A Levi; I Lax; Towia Libermann; Y Yarden
Regulation of cell proliferation by epidermal growth factor.
CRC critical reviews in biochemistry 1983;14(2):93-111.
1982: W Birchmeier; Towia Libermann; B A Imhof; T E Kreis
Intracellular and extracellular components involved in the formation of ventral surfaces of fibroblasts.
Cold Spring Harbor symposia on quantitative biology 1982;46 Pt 2():755-67.
1982: J Schlessinger; A B Schreiber; I Lax; Y Yashuv-Gan; Towia Libermann; G M Hillman; A Levi; Y Yarden
Molecular steps in the action and regulation of epidermal growth factor: a cellular mitogen.
Progress in clinical and biological research 1982;91():359-72.
1980: B A Imhof; H J Acha-Orbea; Towia Libermann; B F Reber; J H Lanz; K H Winterhalter; W Birchmeier
Phosphorylation and dephosphorylation of spectrin from human erythrocyte ghosts under physiological conditions: autocatalysis rather than reaction with separate kinase and phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(6):3264-8.