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Michael Bittner

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Oligonucleotide Array Sequence Analysis

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Sungwon Jung; Jeff Kiefer; Michael Berens; Michael Bittner; Daniel Von Hoff; Michael Verdicchio; Seungchan Kim
Learning contextual gene set interaction networks of cancer with condition specificity.
Jianping Hua; Sonsoles Shack; Chao Sima; Edward A Smith; Jeffrey M. Trent; Lalitamba Alla; Milana Cypert; Edward R Dougherty; Gerald C Gooden; Michael Bittner
Tracking transcriptional activities with high-content epifluorescent imaging.
Michael Bittner; Edward R Dougherty
Newton, laplace, and the epistemology of systems biology.

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All Publications

2013: Sungwon Jung; Jeff Kiefer; Michael Berens; Michael Bittner; Daniel Von Hoff; Michael Verdicchio; Seungchan Kim
Learning contextual gene set interaction networks of cancer with condition specificity.
BMC genomics 2013;14():110.
2012: Jianping Hua; Sonsoles Shack; Chao Sima; Edward A Smith; Jeffrey M. Trent; Lalitamba Alla; Milana Cypert; Edward R Dougherty; Gerald C Gooden; Michael Bittner
Tracking transcriptional activities with high-content epifluorescent imaging.
Journal of biomedical optics 2012;17(4):046008.
2012: Michael Bittner; Edward R Dougherty
Newton, laplace, and the epistemology of systems biology.
Cancer informatics 2012;11():185-90.
2012: Xiangfang Li; Lijun Qian; Michael Bittner; Edward R Dougherty
A Systems Biology Approach in Therapeutic Response Study for Different Dosing Regimens-a Modeling Study of Drug Effects on Tumor Growth using Hybrid Systems.
Cancer informatics 2012;11():41-60.
2011: Xiangfang Lindsey Li; Lijun Qian; Michael Bittner; Edward R Dougherty
Characterization of drug efficacy regions based on dosage and frequency schedules.
IEEE transactions on bio-medical engineering 2011;58(3):488-98.
2011: Ritwik Layek; Aniruddha Datta; Michael Bittner; Edward R Dougherty
Cancer therapy design based on pathway logic.
Bioinformatics (Oxford, England) 2011;27(4):548-55.
2010: Daniel Von Hoff; Joseph J Stephenson; Peter Rosen; David M Loesch; Mitesh J Borad; Stephen Anthony; Gayle Jameson; Susan Brown; Nina Cantafio; Donald A Richards; Tom R Fitch; Ernesto Wasserman; Cristian Fernandez; Sylvan Green; William Sutherland; Michael Bittner; Arlet Alarcon; David Mallery; Robert J Penny
Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments for their refractory cancers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(33):4877-83.
2010: Aleksandar Sekulic; Su Y Kim; Galen Hostetter; Stephanie Savage; Janine G Einspahr; Anil Prasad; Paul Sagerman; Clara Curiel-Lewandrowski; Robert Krouse; George Bowden; James Warneke; David S Alberts; Mark R Pittelkow; David DiCaudo; Brian J Nickoloff; Jeffrey M. Trent; Michael Bittner
Loss of inositol polyphosphate 5-phosphatase is an early event in development of cutaneous squamous cell carcinoma.
Cancer prevention research (Philadelphia, Pa.) 2010;3(10):1277-83.
2010: Edward R Dougherty; Michael Bittner
Causality, randomness, intelligibility, and the epistemology of the cell.
Current genomics 2010;11(4):221-37.
2010: Blaise Hanczar; Jianping Hua; Chao Sima; John Weinstein; Michael Bittner; Edward R Dougherty
Small-sample precision of ROC-related estimates.
Bioinformatics (Oxford, England) 2010;26(6):822-30.
2010: Muriel Brengues; Brigitte Paap; Michael Bittner; Sally A Amundson; Bruce Seligmann; Ronald Korn; Ralf Lenigk; Fredderic Zenhausern
Biodosimetry on small blood volume using gene expression assay.
Health physics 2010;98(2):179-85.
2010: Chen Zhao; Michael Bittner; Robert S Chapkin; Edward R Dougherty
Characterization of the effectiveness of reporting lists of small feature sets relative to the accuracy of the prior biological knowledge.
Cancer informatics 2010;9():49-60.
2010: Galen Hostetter; Su Young Kim; Stephanie Savage; Gerald C Gooden; Michael Barrett; Jian Zhang; Lalitamba Alla; April Watanabe; Janine Einspahr; Anil Prasad; Brian J Nickoloff; John D Carpten; Jeffrey M. Trent; David Alberts; Michael Bittner
Random DNA fragmentation allows detection of single-copy, single-exon alterations of copy number by oligonucleotide array CGH in clinical FFPE samples.
Nucleic acids research 2010;38(2):e9.
2009: Edward R Dougherty; Marcel Brun; Jeffrey M. Trent; Michael Bittner
Conditioning-based modeling of contextual genomic regulation.
IEEE/ACM transactions on computational biology and bioinformatics / IEEE, ACM 2009;6(2):310-20.
2009: Ina Sen; Michael P Verdicchio; Sungwon Jung; Robert Trevino; Michael Bittner; Seungchan Kim
Context-specific gene regulations in cancer gene expression data.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2009;():75-86.
2008: Sally A Amundson; Khanh T Do; Lisa C Vinikoor; R Anthony Lee; Christine A Koch-Paiz; Jaeyong Ahn; Mark Reimers; Yidong Chen; Dominic A Scudiero; John N Weinstein; Jeffrey M. Trent; Michael Bittner; Paul S Meltzer; Albert J Fornace
Integrating global gene expression and radiation survival parameters across the 60 cell lines of the National Cancer Institute Anticancer Drug Screen.
Cancer research 2008;68(2):415-24.
2007: Giuliana Salvatore; Tito Claudio Nappi; Paolo Salerno; Yuan Jiang; Corrado Garbi; Clara Ugolini; Paolo Miccoli; Fulvio Basolo; Maria Domenica Castellone; Anna Maria Cirafici; Rosa Marina Melillo; Alfredo Fusco; Michael Bittner; Massimo Santoro
A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma.
Cancer research 2007;67(21):10148-58.
2007: Myoyong Lee; Jeffrey M. Trent; Michael Bittner
Optimization of oligonucleotide microarray fabricated by spotting 65-mer.
Analytical biochemistry 2007;368(1):61-9.
2007: Myoyong Lee; Charlie C Xiang; Jeffrey M. Trent; Michael Bittner
Performance characteristics of 65-mer oligonucleotide microarrays.
Analytical biochemistry 2007;368(1):70-8.
2007: John D Carpten; Andrew L Faber; Candice Horn; Gregory P Donoho; Stephen L Briggs; Christiane M Robbins; Galen Hostetter; Sophie Boguslawski; Tracy Y Moses; Stephanie Savage; Mark Uhlik; Aimin Lin; Jian Du; Yue-Wei Qian; Douglas J Zeckner; Greg Tucker-Kellogg; Jeffrey W Touchman; Ketan Patel; Spyro Mousses; Michael Bittner; Richard Schevitz; Mei-Huei T Lai; Kerry L Blanchard; James E Thomas
A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
Nature 2007;448(7152):439-44.
2007: Samudra K Dissanayake; Michael Wade; Carrie E Johnson; Michael O'Connell; Poloko D Leotlela; Amanda D French; Kavita V Shah; Kyle J Hewitt; Devin T Rosenthal; Fred E Indig; Yuan Jiang; Brian J Nickoloff; Dennis D Taub; Jeffrey M. Trent; Randall T Moon; Michael Bittner; Ashani T Weeraratna
The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.
The Journal of biological chemistry 2007;282(23):17259-71.
2007: E Dehan; Amir Ben-Dor; W Liao; Doron Lipson; H Frimer; Shlomit Rienstein; David A Simansky; Meir Krupsky; Penina Yaron; Eitan Friedman; Gideon Rechavi; M Perlman; Ayala Aviram-Goldring; Shai Izraeli; Michael Bittner; Zohar Yakhini; Naftali Kaminski
Chromosomal aberrations and gene expression profiles in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2007;56(2):175-84.
2007: Edward R Doughtery; Hua Jianping; Michael Bittner
Validation of computational methods in genomics.
Current genomics 2007;8(1):1-19.
2007: Nestor Walter Trepode; Hugo Aguirre Armelin; Michael Bittner; Junior Barrera; Marco Dimas Gubitoso; Ronaldo Fumio Hashimoto
A robust structural PGN model for control of cell-cycle progression stabilized by negative feedbacks.
EURASIP journal on bioinformatics & systems biology 2007;():73109.
2007: Seungchan Kim; Ina Sen; Michael Bittner
Mining molecular contexts of cancer via in-silico conditioning.
Computational systems bioinformatics / Life Sciences Society. Computational Systems Bioinformatics Conference 2007;6():169-79.
2006: Ashish Choudhary; Aniruddha Datta; Michael Bittner; Edward R Dougherty
Intervention in a family of Boolean networks.
Bioinformatics (Oxford, England) 2006;22(2):226-32.
2006: Jianping Hua; yoganand balagurunathan; Yidong Chen; James Lowey; Michael Bittner; Zixiang Xiong; Edward Suh; Edward R Dougherty
Normalization benefits microarray-based classification.
EURASIP journal on bioinformatics & systems biology 2006;():43056.
2006: Sergei A Aksyonov; Michael Bittner; Linda B Bloom; Linda J Reha-Krantz; Ian R Gould; Mark Hays; Urban A Kiernan; Eric E Niederkofler; Vincent Pizziconi; Raul S Rivera; Daniel J B Williams; Peter Williams
Multiplexed DNA sequencing-by-synthesis.
Analytical biochemistry 2006;348(1):127-38.
2005: Ranadip Pal; Ivan Ivanov; Aniruddha Datta; Michael Bittner; Edward R Dougherty
Generating Boolean networks with a prescribed attractor structure.
Bioinformatics (Oxford, England) 2005;21(21):4021-5.
2005: Sally A Amundson; Khanh T Do; Lisa Vinikoor; Christine A Koch-Paiz; Michael Bittner; Jeffrey M. Trent; Paul Meltzer; Albert J Fornace
Stress-specific signatures: expression profiling of p53 wild-type and -null human cells.
Oncogene 2005;24(28):4572-9.
2005: Ranadip Pal; Aniruddha Datta; Albert J Fornace; Michael Bittner; Edward R Dougherty
Boolean relationships among genes responsive to ionizing radiation in the NCI 60 ACDS.
Bioinformatics (Oxford, England) 2005;21(8):1542-9.
2005: Ranadip Pal; Aniruddha Datta; Michael Bittner; Edward R Dougherty
Intervention in context-sensitive probabilistic Boolean networks.
Bioinformatics (Oxford, England) 2005;21(7):1211-8.
2005: Michael Bittner
A window on the dynamics of biological switches.
Nature biotechnology 2005;23(2):183-4.
2004: Xiaobo Zhou; Xiaodong Wang; Ranadip Pal; Ivan Ivanov; Michael Bittner; Edward R Dougherty
A Bayesian connectivity-based approach to constructing probabilistic gene regulatory networks.
Bioinformatics (Oxford, England) 2004;20(17):2918-27.
2004: Sanju Attoor; Edward R Dougherty; Yidong Chen; Michael Bittner; Jeffrey M. Trent
Which is better for cDNA-microarray-based classification: ratios or direct intensities.
Bioinformatics (Oxford, England) 2004;20(16):2513-20.
2004: yoganand balagurunathan; Naisyin Wang; Edward R Dougherty; Danh V Nguyen; Yidong Chen; Michael Bittner; Jeffrey M. Trent; Raymond Carroll
Noise factor analysis for cDNA microarrays.
Journal of biomedical optics 2004;9(4):663-78.
2004: Ronaldo F Hashimoto; Seungchan Kim; Ilya Shmulevich; Wei Zhang; Michael Bittner; Edward R Dougherty
Growing genetic regulatory networks from seed genes.
Bioinformatics (Oxford, England) 2004;20(8):1241-7.
2004: Christine A Koch-Paiz; Sally A Amundson; Michael Bittner; Paul S Meltzer; Albert J Fornace
Functional genomics of UV radiation responses in human cells.
Mutation research 2004;549(1-2):65-78.
2004: Aniruddha Datta; Ashish Choudhary; Michael Bittner; Edward R Dougherty
External control in Markovian genetic regulatory networks: the imperfect information case.
Bioinformatics (Oxford, England) 2004;20(6):924-30.
2004: Ashani T Weeraratna; Dorothea Becker; Kristen M Carr; Paul H Duray; Kevin P Rosenblatt; Sherry Yang; Yidong Chen; Michael Bittner; Robert L Strausberg; Gregory J Riggins; Urs Wagner; Olli Kallioniemi; Jeffrey M. Trent; Patrice J Morin; Paul S Meltzer
Generation and analysis of melanoma SAGE libraries: SAGE advice on the melanoma transcriptome.
Oncogene 2004;23(12):2264-74.
2003: Sally A Amundson; Michael Bittner; Albert J Fornace
Functional genomics as a window on radiation stress signaling.
Oncogene 2003;22(37):5828-33.
2003: Roberto Bomprezzi; Markus Ringnér; Seungchan Kim; Michael Bittner; Javed Khan; Yidong Chen; Abdel G Elkahloun; Aimee Yu; Bibiana Bielekova; Paul S Meltzer; Roland Martin; Henry McFarland; Jeffrey M. Trent
Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease.
Human molecular genetics 2003;12(17):2191-9.
2003: Kristen M Carr; Michael Bittner; Jeffrey M. Trent
Gene-expression profiling in human cutaneous melanoma.
Oncogene 2003;22(20):3076-80.
2003: Sally A Amundson; Richard Anthony Lee; Christine A Koch-Paiz; Michael Bittner; Paul Meltzer; Jeffrey M. Trent; Albert J Fornace
Differential responses of stress genes to low dose-rate gamma irradiation.
Molecular cancer research : MCR 2003;1(6):445-52.
2002: Yidong Chen; Vishnu Kamat; Edward R Dougherty; Michael Bittner; Paul S Meltzer; Jeffrey M. Trent
Ratio statistics of gene expression levels and applications to microarray data analysis.
Bioinformatics (Oxford, England) 2002;18(9):1207-15.
2002: yoganand balagurunathan; Edward R Dougherty; Yidong Chen; Michael Bittner; Jeffrey M. Trent
Simulation of cDNA microarrays via a parameterized random signal model.
Journal of biomedical optics 2002;7(3):507-23.
2002: Stacie K Loftus; Denise M Larson; Laura L Baxter; Anthony Antonellis; Yidong Chen; Xufeng Wu; Yuan Jiang; Michael Bittner; John A Hammer; William J Pavan
Mutation of melanosome protein RAB38 in chocolate mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4471-6.
2002: Ashani T Weeraratna; Yuan Jiang; Galen Hostetter; Kevin P Rosenblatt; Paul H Duray; Michael Bittner; Jeffrey M. Trent
Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma.
Cancer cell 2002;1(3):279-88.
2002: Mattias Wahde; Gregory T Klus; Michael Bittner; Yidong Chen; Zoltan Szallasi
Assessing the significance of consistently mis-regulated genes in cancer associated gene expression matrices.
Bioinformatics (Oxford, England) 2002;18(3):389-94.
2002: Albert J Fornace; Sally A Amundson; Khanh T Do; Paul Meltzer; Jeffrey M. Trent; Michael Bittner
Stress-gene induction by low-dose gamma irradiation.
Military medicine 2002;167(2 Suppl):13-5.
2002: Seungchan Kim; Edward R Dougherty; Junior Barrera; Yidong Chen; Michael Bittner; Jeffrey M. Trent
Strong feature sets from small samples.
Journal of computational biology : a journal of computational molecular cell biology 2002;9(1):127-46.
2002: Edward R Dougherty; Junior Barrera; Marcel Brun; Seungchan Kim; Roberto M Cesar; Yidong Chen; Michael Bittner; Jeffrey M. Trent
Inference from clustering with application to gene-expression microarrays.
Journal of computational biology : a journal of computational molecular cell biology 2002;9(1):105-26.
2002: Javed Khan; Lao H Saal; Michael Bittner; Yuan Jiang; Gerald C Gooden; Arthur A Glatfelter; Paul S Meltzer
Gene expression profiling in cancer using cDNA microarrays.
Methods in molecular medicine 2002;68():205-22.
2002: Syed Shaheduzzaman; Vyjayanthi Krishnan; Ana Petrovic; Michael Bittner; Paul Meltzer; Jeffrey M. Trent; Sundararajan Venkatesan; Steven L Zeichner
Effects of HIV-1 Nef on cellular gene expression profiles.
Journal of biomedical science 2002;9(1):82-96.
2001: Sally A Amundson; Michael Bittner; Paul Meltzer; Jeffrey M. Trent; Albert J Fornace
Induction of gene expression as a monitor of exposure to ionizing radiation.
Radiation research 2001;156(5 Pt 2):657-61.
2001: Spyro Mousses; Urs Wagner; Yidong Chen; J W Kim; Lukas Bubendorf; Michael Bittner; T Pretlow; Abdel G Elkahloun; Jane Trepel; Olli Kallioniemi
Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling.
Oncogene 2001;20(46):6718-23.
2001: P W Ng; H Iha; Y Iwanaga; Michael Bittner; Yidong Chen; Yuan Jiang; Gerald C Gooden; Jeffrey M. Trent; Paul Meltzer; Kuan-Teh Jeang; Steven L Zeichner
Genome-wide expression changes induced by HTLV-1 Tax: evidence for MLK-3 mixed lineage kinase involvement in Tax-mediated NF-kappaB activation.
Oncogene 2001;20(33):4484-96.
2001: Sally A Amundson; Michael Bittner; Paul Meltzer; Jeffrey M. Trent; Albert J Fornace
Biological indicators for the identification of ionizing radiation exposure in humans.
Expert review of molecular diagnostics 2001;1(2):211-9.
2001: Sally A Amundson; Michael Bittner; Paul Meltzer; Jeffrey M. Trent; Albert J Fornace
Physiological function as regulation of large transcriptional programs: the cellular response to genotoxic stress.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2001;129(4):703-10.
2001: Gregory T Klus; N Rokaeus; Michael Bittner; Yidong Chen; Dorian Korz; Saraswati Sukumar; A Schick; Zoltan Szallasi
Down-regulation of the desmosomal cadherin desmocollin 3 in human breast cancer.
International journal of oncology 2001;19(1):169-74.
2001: Jun Luo; David Duggan; Yidong Chen; Jurga Sauvageot; Charles M Ewing; Michael Bittner; Jeffrey M. Trent; William B Isaacs
Human prostate cancer and benign prostatic hyperplasia: molecular dissection by gene expression profiling.
Cancer research 2001;61(12):4683-8.
2001: Outi Monni; M Barlund; Spyro Mousses; Juha Kononen; Guido Sauter; Mervi Heiskanen; P Paavola; Kristiina Avela; Yidong Chen; Michael Bittner; Anne Kallioniemi
Comprehensive copy number and gene expression profiling of the 17q23 amplicon in human breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5711-6.
2001: P Meltzer; Michael Bittner
Chromosome microdissection.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] 2001;Chapter 4():Unit4.8.
2001: Yuan Jiang; J Lueders; Arthur A Glatfelter; C Gooden; Michael Bittner
Profiling human gene expression with cDNA microarrays.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] 2001;Chapter 11():Unit 11.3.
2001: Yuan Jiang; J Lueders; Arthur A Glatfelter; C Gooden; Michael Bittner
Profiling human gene expression with cDNA microarrays.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2001;Chapter 22():Unit 22.3.
2001: Mini Paulose-Murphy; N K Ha; C Xiang; Yidong Chen; L Gillim; Robert Yarchoan; Paul Meltzer; Michael Bittner; Jeffrey M. Trent; Steven L Zeichner
Transcription program of human herpesvirus 8 (kaposi's sarcoma-associated herpesvirus).
Journal of virology 2001;75(10):4843-53.
2001: Ingrid Hedenfalk; DJ Duggan; Yidong Chen; Michael D Radmacher; Michael Bittner; R Simon; Paul Meltzer; B Gusterson; M Esteller; Olli Kallioniemi; Benjamin S Wilfond; Ake Borg; Jeffrey M. Trent; Mark Raffeld; Zohar Yakhini; Amir Ben-Dor; Edward R Dougherty; Juha Kononen; Lukas Bubendorf; W Fehrle; S Pittaluga; S Gruvberger; Niklas Loman; Oskar T Johannsson; Håkan Olsson; Guido Sauter
Gene-expression profiles in hereditary breast cancer.
The New England journal of medicine 2001;344(8):539-48.
2001: Yidong Chen; Zohar Yakhini; Amir Ben-Dor; Edward R Dougherty; Jeffrey M. Trent; Michael Bittner
Analysis of expression patterns: the scope of the problem, the problem of scope.
Disease markers 2001;17(2):59-65.
2001: Ritva Karhu; Minna Ahlstedt-Soini; Michael Bittner; P Meltzer; Jeffrey M. Trent; Jorma Isola
Chromosome arm-specific multicolor FISH.
Genes, chromosomes & cancer 2001;30(1):105-9.
2000: Seungchan Kim; Edward R Dougherty; Michael Bittner; Yidong Chen; K Sivakumar; Paul Meltzer; Jeffrey M. Trent
General nonlinear framework for the analysis of gene interaction via multivariate expression arrays.
Journal of biomedical optics 2000;5(4):411-24.
2000: Sally A Amundson; Khanh T Do; S Shahab; Michael Bittner; Paul Meltzer; Jeffrey M. Trent; Albert J Fornace
Identification of potential mRNA biomarkers in peripheral blood lymphocytes for human exposure to ionizing radiation.
Radiation research 2000;154(3):342-6.
2000: Michael Bittner; Paul Meltzer; Yidong Chen; Yuan Jiang; E Seftor; M Hendrix; Michael D Radmacher; R Simon; Zohar Yakhini; Amir Ben-Dor; Nick Sampas; Edward R Dougherty; E Wang; F Marincola; C Gooden; J Lueders; Arthur A Glatfelter; Pam Pollock; John D Carpten; Elizabeth M Gillanders; D Leja; K Dietrich; Christian Beaudry; Michael Berens; D Alberts; V Sondak
Molecular classification of cutaneous malignant melanoma by gene expression profiling.
Nature 2000;406(6795):536-40.
2000: Maarit Bärlund; F Forozan; Juha Kononen; Lukas Bubendorf; Yidong Chen; Michael Bittner; Joachim Torhorst; Philippe Haas; christoph bucher; Guido Sauter; Olli Kallioniemi; Anne Kallioniemi
Detecting activation of ribosomal protein S6 kinase by complementary DNA and tissue microarray analysis.
Journal of the National Cancer Institute 2000;92(15):1252-9.
2000: K Kudoh; M Ramanna; Roald Ravatn; Abdel G Elkahloun; Michael Bittner; Paul S Meltzer; Jeffrey M. Trent; W S Dalton; Khew-Voon Chin
Monitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray.
Cancer research 2000;60(15):4161-6.
2000: Seungchan Kim; E R Dougherty; Yidong Chen; K Sivakumar; Paul Meltzer; Jeffrey M. Trent; Michael Bittner
Multivariate measurement of gene expression relationships.
Genomics 2000;67(2):201-9.
2000: Yan Su; Michael Bittner; Yidong Chen; L Tao; Y Jiang; Y Zhang; Dietrich A Stephan; Jeffrey M. Trent
Identification of tumor-suppressor genes using human melanoma cell lines UACC903, UACC903(+6), and SRS3 by comparison of expression profiles.
Molecular carcinogenesis 2000;28(2):119-27.
2000: Joop Wiegant; Vladimir Bezrookove; Carla Rosenberg; Hans J Tanke; Anton K Raap; H Zhang; Michael Bittner; Jeffrey M. Trent; P Meltzer
Differentially painting human chromosome arms with combined binary ratio-labeling fluorescence in situ hybridization.
Genome research 2000;10(6):861-5.
2000: Dietrich A Stephan; Yidong Chen; Y Jiang; L Malechek; J Z Gu; Christiane M Robbins; Michael Bittner; JA Morris; ED Carstea; Paul S Meltzer; K Adler; R Garlick; Jeffrey M. Trent; MA Ashlock
Positional cloning utilizing genomic DNA microarrays: the Niemann-Pick type C gene as a model system.
Molecular genetics and metabolism 2000;70(1):10-8.
2000: Mervi Heiskanen; Michael Bittner; Yidong Chen; Javed Khan; K E Adler; Jeffrey M. Trent; Paul S Meltzer
Detection of gene amplification by genomic hybridization to cDNA microarrays.
Cancer research 2000;60(4):799-802.
1999: Javed Khan; Michael Bittner; Lao H Saal; U Teichmann; David Azorsa; Gerald C Gooden; William J Pavan; Jeffrey M. Trent; Paul S Meltzer
cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13264-9.
1999: Stacie K Loftus; Yidong Chen; Gerald C Gooden; Joseph F Ryan; G Birznieks; M Hilliard; Andreas D Baxevanis; Michael Bittner; Paul Meltzer; Jeffrey M. Trent; William J Pavan
Informatic selection of a neural crest-melanocyte cDNA set for microarray analysis.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(16):9277-80.
1999: Michael Bittner; Paul Meltzer; Jeffrey M. Trent
Data analysis and integration: of steps and arrows.
Nature genetics 1999;22(3):213-5.
1999: Sally A Amundson; Michael Bittner; Yidong Chen; Jeffrey M. Trent; Paul Meltzer; Albert J Fornace
Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses.
Oncogene 1999;18(24):3666-72.
1999: Javed Khan; Michael Bittner; Yidong Chen; Paul S Meltzer; Jeffrey M. Trent
DNA microarray technology: the anticipated impact on the study of human disease.
Biochimica et biophysica acta 1999;1423(2):M17-28.
1999: EF Nuwaysir; Michael Bittner; Jeffrey M. Trent; J Carl Barrett; Cynthia A Afshari
Microarrays and toxicology: the advent of toxicogenomics.
Molecular carcinogenesis 1999;24(3):153-9.
1999: Javed Khan; Lao H Saal; Michael Bittner; Yidong Chen; Jeffrey M. Trent; Paul S Meltzer
Expression profiling in cancer using cDNA microarrays.
Electrophoresis 1999;20(2):223-9.
1999: Albert J Fornace; Sally A Amundson; Michael Bittner; Timothy G Myers; Paul Meltzer; J N Weinsten; Jeffrey M. Trent
The complexity of radiation stress responses: analysis by informatics and functional genomics approaches.
Gene expression 1999;7(4-6):387-400.
1999: DJ Duggan; Michael Bittner; Yidong Chen; Paul Meltzer; Jeffrey M. Trent
Expression profiling using cDNA microarrays.
Nature genetics 1999;21(1 Suppl):10-4.
1998: Javed Khan; R Simon; Michael Bittner; Yidong Chen; S B Leighton; Thomas J Pohida; Paul D Smith; Yuan Jiang; Gerald C Gooden; Jeffrey M. Trent; Paul S Meltzer
Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays.
Cancer research 1998;58(22):5009-13.
1998: O Ermolaeva; M Rastogi; Kim D Pruitt; G D Schuler; Michael Bittner; Yidong Chen; R Simon; Paul Meltzer; Jeffrey M. Trent; Mark S Boguski
Data management and analysis for gene expression arrays.
Nature genetics 1998;20(1):19-23.
1998: Elisabeth P Nacheva; Colin Grace; Michael Bittner; David Ledbetter; R B Jenkins; Anthony R Green
Comparative genomic hybridization: a comparison with molecular and cytogenetic analysis.
Cancer genetics and cytogenetics 1998;100(2):93-105.
1998: Steffen Dietzel; Anna Jauch; D Kienle; G Qu; Heidi Holtgreve-Grez; Roland Eils; C Münkel; Michael Bittner; P S Meltzer; Jeffrey M. Trent; Thomas Cremer
Separate and variably shaped chromosome arm domains are disclosed by chromosome arm painting in human cell nuclei.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 1998;6(1):25-33.
1998: Bernhard Holzmann; U Gosslar; Michael Bittner
alpha 4 integrins and tumor metastasis.
Current topics in microbiology and immunology 1998;231():125-41.
1997: Siradanahalli Guru; SE Olufemi; P Manickam; C Cummings; L M Gieser; BL Pike; Michael Bittner; Y Jiang; A C Chinault; N J Nowak; A Brzozowska; Judy S Crabtree; Y Wang; BA Roe; JM Weisemann; Mark S Boguski; Sunita K Agarwal; A Lee Burns; Allen Spiegel; Stephen J Marx; W L Flejter; P J de Jong; Francis S Collins; Settara C Chandrasekharappa
A 2.8-Mb clone contig of the multiple endocrine neoplasia type 1 (MEN1) region at 11q13.
Genomics 1997;42(3):436-45.
1997: C Y Linder; Abdel G Elkahloun; Michael Bittner; Jeffrey M. Trent; Paul S Meltzer
Restriction mapping of recombinant cosmid clones using lambda terminase and field inversion gel electrophoresis.
Analytical biochemistry 1997;245(1):105-7.
1997: Jeffrey M. Trent; Michael Bittner; J Zhang; R Wiltshire; M Ray; Y Su; E Gracia; Paul Meltzer; J De Risi; L Penland; P Brown
Use of microgenomic technology for analysis of alterations in DNA copy number and gene expression in malignant melanoma.
Clinical and experimental immunology 1997;107 Suppl 1():33-40.
1997: Peter J Mogayzel; KA Henning; Michael Bittner; Elizabeth A Novotny; E M Schwiebert; William B Guggino; Y Jiang; MA Rosenfeld
Functional human CFTR produced by stable Chinese hamster ovary cell lines derived using yeast artificial chromosomes.
Human molecular genetics 1997;6(1):59-68.
1996: Abdel G Elkahloun; Michael Bittner; K Hoskins; Robert M Gemmill; Paul S Meltzer
Molecular cytogenetic characterization and physical mapping of 12q13-15 amplification in human cancers.
Genes, chromosomes & cancer 1996;17(4):205-14.
1996: Joe L DeRisi; L Penland; Patrick O Brown; Michael Bittner; Paul S Meltzer; M Ray; Yidong Chen; Yan A Su; Jeffrey M. Trent
Use of a cDNA microarray to analyse gene expression patterns in human cancer.
Nature genetics 1996;14(4):457-60.
1996: XY Guan; H Zhang; Michael Bittner; Y Jiang; Paul Meltzer; Jeffrey M. Trent
Chromosome arm painting probes.
Nature genetics 1996;12(1):10-1.
1995: Mieke Schutte; LT da Costa; Christopher A Moskaluk; E Rozenblum; X Guan; P J de Jong; Michael Bittner; P S Meltzer; Jeffrey M. Trent; Scott E Kern
Isolation of YAC insert sequences by representational difference analysis.
Nucleic acids research 1995;23(20):4127-33.
1995: R N Wiltshire; P Duray; Michael Bittner; T Visakorpi; Paul S Meltzer; R J Tuthill; L A Liotta; Jeffrey M. Trent
Direct visualization of the clonal progression of primary cutaneous melanoma: application of tissue microdissection and comparative genomic hybridization.
Cancer research 1995;55(18):3954-7.
1995: XY Guan; C B Cargile; Sarah L Anzick; F H Thompson; Paul S Meltzer; Michael Bittner; Raymond M Taetle; J R McGill; Jeffrey M. Trent
Chromosome microdissection identifies cryptic sites of DNA sequence amplification in human ovarian carcinoma.
Cancer research 1995;55(15):3380-5.
1995: Mieke Schutte; LT da Costa; Stephan Hahn; Christopher A Moskaluk; A T Hoque; E Rozenblum; C L Weinstein; Michael Bittner; P S Meltzer; Jeffrey M. Trent
Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(13):5950-4.
1995: Thomas Roitsch; Michael Bittner; D E Godt
Induction of apoplastic invertase of Chenopodium rubrum by D-glucose and a glucose analog and tissue-specific expression suggest a role in sink-source regulation.
Plant physiology 1995;108(1):285-94.
1988: S Wee; J B Neilands; Michael Bittner; B C Hemming; B L Haymore; R Seetharam
Expression, isolation and properties of Fur (ferric uptake regulation) protein of Escherichia coli K 12.
Biology of metals 1988;1(1):62-8.
1985: G G Krivi; Michael Bittner; E Rowold; E Y Wong; K C Glenn; K S Rose; D C Tiemeier
Purification of recA-based fusion proteins by immunoadsorbent chromatography. Characterization of a major antigenic determinant of Escherichia coli recA protein.
The Journal of biological chemistry 1985;260(18):10263-7.
1983: R T Fraley; S G Rogers; R B Horsch; P R Sanders; J S Flick; S P Adams; Michael Bittner; L A Brand; C L Fink; J S Fry; G R Galluppi; S B Goldberg; N L Hoffmann; S C Woo
Expression of bacterial genes in plant cells.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(15):4803-7.
1982: Michael Bittner; D Vapnek
Cloning vectors derived from bacterial plasmids.
Basic life sciences 1982;19():29-49.