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Heather Cunliffe

Research Profile

Disorders

Breast Neoplasms

Chemicals & Drugs

Physiology

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Publications

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Siker Kimbung; Niklas Loman; Astrid Ottosson-Wadlund; Ida Johansson; Kristina Aaltonen; Pontus Berglund; Ewa Biskup; Heather Cunliffe; Bengt Fadeel; Sofia Gruvberger-Saal; Ingrid Hedenfalk
Co-targeting of the PI3K pathway improves the response of BRCA1 deficient breast cancer cells to PARP1 inhibition.
Yan W Asmann; Tiffany R Baker; Jennifer M Carr; Heather Cunliffe; Caroline Davis; Julie E Getz; Asif Hossain; Galen Hostetter; Krishna R Kalari; Xing Li; Sarah A McLaughlin; Brian M Necela; Edith A Perez; Derek C Radisky; Gary P Schroth; E Aubrey Thompson
Detection of redundant fusion transcripts as biomarkers or disease-specific therapeutic targets in breast cancer.
Eric A Ariazi; yoganand balagurunathan; Heather Cunliffe; Helen R Kim; Joan S Lewis-Wambi; Emmanuelle Nicolas; Pilar Ramos; Eric A Ross; Catherine G N Sharma; Michael J Slifker; Coya Tapia; Amanda L Willis; Smitha Yerrum; V Craig Jordan
Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time.

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All Publications

2012: Siker Kimbung; Niklas Loman; Astrid Ottosson-Wadlund; Ida Johansson; Kristina Aaltonen; Pontus Berglund; Ewa Biskup; Heather Cunliffe; Bengt Fadeel; Sofia Gruvberger-Saal; Ingrid Hedenfalk
Co-targeting of the PI3K pathway improves the response of BRCA1 deficient breast cancer cells to PARP1 inhibition.
Cancer letters 2012;319(2):232-41.
2012: Yan W Asmann; Tiffany R Baker; Jennifer M Carr; Heather Cunliffe; Caroline Davis; Julie E Getz; Asif Hossain; Galen Hostetter; Krishna R Kalari; Xing Li; Sarah A McLaughlin; Brian M Necela; Edith A Perez; Derek C Radisky; Gary P Schroth; E Aubrey Thompson
Detection of redundant fusion transcripts as biomarkers or disease-specific therapeutic targets in breast cancer.
Cancer research 2012;72(8):1921-8.
2011: Eric A Ariazi; yoganand balagurunathan; Heather Cunliffe; Helen R Kim; Joan S Lewis-Wambi; Emmanuelle Nicolas; Pilar Ramos; Eric A Ross; Catherine G N Sharma; Michael J Slifker; Coya Tapia; Amanda L Willis; Smitha Yerrum; V Craig Jordan
Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(47):18879-86.
2011: V Craig Jordan; Helen R Kim; Ifeyinwa Obiorah; Eric A Ariazi; Heather Cunliffe; Ping Fan; Hiltrud Brauch
The St. Gallen Prize Lecture 2011: evolution of long-term adjuvant anti-hormone therapy: consequences and opportunities.
Breast (Edinburgh, Scotland) 2011;20 Suppl 3():S1-11.
2011: Sara Nasser; Heather Cunliffe; Michael A Black; Seungchan Kim
Context-specific gene regulatory networks subdivide intrinsic subtypes of breast cancer.
BMC bioinformatics 2011;12 Suppl 2():S3.
2010: Eric A Ariazi; Eugen Brailoiu; Smitha Yerrum; Heather A Shupp; Michael J Slifker; Heather Cunliffe; Michael A Black; Anne L Donato; Jeffrey B Arterburn; Tudor I Oprea; Eric R Prossnitz; Nae J Dun; V Craig Jordan
The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells.
Cancer research 2010;70(3):1184-94.
2010: Karin Rennstam; Anita Ringberg; Heather Cunliffe; Håkan Olsson; Göran Landberg; Ingrid Hedenfalk
Genomic alterations in histopathologically normal breast tissue from BRCA1 mutation carriers may be caused by BRCA1 haploinsufficiency.
Genes, chromosomes & cancer 2010;49(1):78-90.
2008: Joan S Lewis-Wambi; Heather Cunliffe; Helen R Kim; Amanda L Willis; V Craig Jordan
Overexpression of CEACAM6 promotes migration and invasion of oestrogen-deprived breast cancer cells.
European journal of cancer (Oxford, England : 1990) 2008;44(12):1770-9.
2008: Amanda L Willis; Nhan L Tran; Julie M Chatigny; Nichole Charlton; Hong Vu; Sharron A N Brown; Michael A Black; Wendy S McDonough; Shannon P Fortin; Joshua R Niska; Jeffrey A Winkles; Heather Cunliffe
The fibroblast growth factor-inducible 14 receptor is highly expressed in HER2-positive breast tumors and regulates breast cancer cell invasive capacity.
Molecular cancer research : MCR 2008;6(5):725-34.
2007: V Craig Jordan; Joan S Lewis-Wambi; Helen Kim; Heather Cunliffe; Eric A Ariazi; Catherine G N Sharma; Heather A Shupp; Ramona F Swaby
Exploiting the apoptotic actions of oestrogen to reverse antihormonal drug resistance in oestrogen receptor positive breast cancer patients.
Breast (Edinburgh, Scotland) 2007;16 Suppl 2():S105-13.
2007: Jeffrey A Winkles; Nhan L Tran; Sharron A N Brown; Nichole Stains; Heather Cunliffe; Michael Berens
Role of TWEAK and Fn14 in tumor biology.
Frontiers in bioscience : a journal and virtual library 2007;12():2761-71.
2006: Sofia K Gruvberger-Saal; Heather Cunliffe; Kristen M Carr; Ingrid Hedenfalk
Microarrays in breast cancer research and clinical practice--the future lies ahead.
Endocrine-related cancer 2006;13(4):1017-31.
2006: Nhan L Tran; Wendy S McDonough; Benjamin A Savitch; Shannon P Fortin; Jeffrey A Winkles; Marc Symons; Mitsutoshi Nakada; Heather Cunliffe; Galen Hostetter; Dominique Hoelzinger; Jessica L Rennert; Jennifer S Michaelson; Linda C Burkly; Christopher A Lipinski; Joseph C Loftus; Luigi Mariani; Michael Berens
Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome.
Cancer research 2006;66(19):9535-42.
2003: Heather Cunliffe; Markus Ringnér; Sven Bilke; Robert L Walker; Jennifer M Cheung; Yidong Chen; Paul S Meltzer
The gene expression response of breast cancer to growth regulators: patterns and correlation with tumor expression profiles.
Cancer research 2003;63(21):7158-66.
2001: David Azorsa; Heather Cunliffe; Paul S Meltzer
Association of steroid receptor coactivator AIB1 with estrogen receptor-alpha in breast cancer cells.
Breast cancer research and treatment 2001;70(2):89-101.
2001: M Scherr; Jeanne LeBon; Daniela Castanotto; Heather Cunliffe; P S Meltzer; Arnold Ganser; Arthur D Riggs; John J Rossi
Detection of antisense and ribozyme accessible sites on native mRNAs: application to NCOA3 mRNA.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(5):454-60.
2001: Paula J Wilderman; Adriana I Vasil; Z Johnson; Megan J Wilson; Heather Cunliffe; Iain L Lamont; Michael Vasil
Characterization of an endoprotease (PrpL) encoded by a PvdS-regulated gene in Pseudomonas aeruginosa.
Infection and immunity 2001;69(9):5385-94.
2000: S Porteous; Elena Torban; N P Cho; Heather Cunliffe; L Chua; LA McNoe; T Ward; C Souza; P Gus; R Giugliani; T Sato; K Yun; J Favor; M Sicotte; Paul Goodyer; Michael Eccles
Primary renal hypoplasia in humans and mice with PAX2 mutations: evidence of increased apoptosis in fetal kidneys of Pax2(1Neu) +/- mutant mice.
Human molecular genetics 2000;9(1):1-11.
1998: Heather Cunliffe; LA McNoe; TA Ward; koenraad devriendt; H G Brunner; Michael Eccles
The prevalence of PAX2 mutations in patients with isolated colobomas or colobomas associated with urogenital anomalies.
Journal of medical genetics 1998;35(10):806-12.
1998: C K Stayner; Heather Cunliffe; TA Ward; Michael Eccles
Cloning and characterization of the human PAX2 promoter.
The Journal of biological chemistry 1998;273(39):25472-9.
1997: M J McConnell; Heather Cunliffe; L J Chua; TA Ward; Michael Eccles
Differential regulation of the human Wilms tumour suppressor gene (WT1) promoter by two isoforms of PAX2.
Oncogene 1997;14(22):2689-700.
1997: Lisa A Schimmenti; Heather Cunliffe; LA McNoe; TA Ward; Michelle C French; HH Shim; Yao-Hua Zhang; W Proesmans; A Leys; K A Byerly; S R Braddock; M Masuno; K Imaizumi; koenraad devriendt; Michael Eccles
Further delineation of renal-coloboma syndrome in patients with extreme variability of phenotype and identical PAX2 mutations.
American journal of human genetics 1997;60(4):869-78.
1996: Urs A Ochsner; Z Johnson; I L Lamont; Heather Cunliffe; Michael Vasil
Exotoxin A production in Pseudomonas aeruginosa requires the iron-regulated pvdS gene encoding an alternative sigma factor.
Molecular microbiology 1996;21(5):1019-28.
1995: Heather Cunliffe; Tony R Merriman; I L Lamont
Cloning and characterization of pvdS, a gene required for pyoverdine synthesis in Pseudomonas aeruginosa: PvdS is probably an alternative sigma factor.
Journal of bacteriology 1995;177(10):2744-50.