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Zhe-Xiong Lian

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Hong-Di Ma; Zhigang Tian; Yan-Ru Deng; Zhe-Xiong Lian
Traditional chinese medicine and immune regulation.
Yugo Ando; Aftab A Ansari; Xiao-Song He; Wenting Huang; Pietro Invernizzi; Kazuhito Kawata; Thomas P Kenny; Patrick S C Leung; Zhe-Xiong Lian; Qianjin Lu; Kazuichi Okazaki; William M Ridgway; Guo-Xiang Yang; Weici Zhang; M Eric Gershwin
Overexpression of microRNA-21 is associated with elevated pro-inflammatory cytokines in dominant-negative TGF-β receptor type II mouse.
Masanobu Tsuda; Koichi tsuneyama; Guo-Xiang Yang; Weici Zhang; Yugo Ando; Aftab A Ansari; Ross L Coppel; Richard Flavell; Bin Gao; Xiao-Song He; Kazuhito Kawata; Patrick S C Leung; Zhe-Xiong Lian; Ogyi Park; William M Ridgway; M Eric Gershwin
Deletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice.

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All Publications

2013: Hong-Di Ma; Zhigang Tian; Yan-Ru Deng; Zhe-Xiong Lian
Traditional chinese medicine and immune regulation.
Clinical reviews in allergy & immunology 2013;44(3):229-41.
2013: Yugo Ando; Aftab A Ansari; Xiao-Song He; Wenting Huang; Pietro Invernizzi; Kazuhito Kawata; Thomas P Kenny; Patrick S C Leung; Zhe-Xiong Lian; Qianjin Lu; Kazuichi Okazaki; William M Ridgway; Guo-Xiang Yang; Weici Zhang; M Eric Gershwin
Overexpression of microRNA-21 is associated with elevated pro-inflammatory cytokines in dominant-negative TGF-β receptor type II mouse.
Journal of autoimmunity 2013;41():111-9.
2013: Masanobu Tsuda; Koichi tsuneyama; Guo-Xiang Yang; Weici Zhang; Yugo Ando; Aftab A Ansari; Ross L Coppel; Richard Flavell; Bin Gao; Xiao-Song He; Kazuhito Kawata; Patrick S C Leung; Zhe-Xiong Lian; Ogyi Park; William M Ridgway; M Eric Gershwin
Deletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice.
Hepatology (Baltimore, Md.) 2013;57(2):806-16.
2012: Yugo Ando; Aftab A Ansari; Ross L Coppel; Xiaosong He; Kazuhito Kawata; Patrick S C Leung; Zhe-Xiong Lian; Takahiko Nakajima; Gary L Norman; Kazuichi Okazaki; William M Ridgway; Masanobu Tsuda; Koichi tsuneyama; Guo-Xiang Yang; Weici Zhang; M Eric Gershwin
The immunobiology of colitis and cholangitis in interleukin-23p19 and interleukin-17A deleted dominant negative form of transforming growth factor beta receptor type II mice.
Hepatology (Baltimore, Md.) 2012;56(4):1418-26.
2012: Qinglong Jin; Kentaro Kikuchi; Zhe-Xiong Lian; Ana Lleo; Hitoshi Moritoki; Yuki Moritoki; Aftab A Ansari; Ross L Coppel; M Eric Gershwin; Gideon M Hirschfield; Pietro Invernizzi; Koichi tsuneyama; Junqi Niu
Comparative analysis of portal cell infiltrates in antimitochondrial autoantibody-positive versus antimitochondrial autoantibody-negative primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2012;55(5):1495-506.
2012: Masanobu Tsuda; John Vierling; Kanji Wakabayashi; Guo-Xiang Yang; Katsunori Yoshida; Weici Zhang; M Eric Gershwin; Zhe-Xiong Lian; Keith Lindor; Yuki Moritoki; Toshio Nakatani; Christopher L Bowlus
Biochemical and immunologic effects of rituximab in patients with primary biliary cirrhosis and an incomplete response to ursodeoxycholic acid.
Hepatology (Baltimore, Md.) 2012;55(2):512-21.
2012: Weici Zhang; Aftab A Ansari; Ross L Coppel; Xiaosong He; Patrick S C Leung; Zhe-Xiong Lian; William M Ridgway; Masanobu Tsuda; Koichi tsuneyama; Guo-Xiang Yang; M Eric Gershwin
Lymphoma-like T cell infiltration in liver is associated with increased copy number of dominant negative form of TGFβ receptor II.
PloS one 2012;7(11):e49413.
2011: Masanobu Tsuda; Koichi tsuneyama; Guo-Xiang Yang; Weici Zhang; Yoko M Ambrosini; Yugo Ando; Aftab A Ansari; Christopher L Bowlus; Ross L Coppel; Xiaosong He; Patrick S C Leung; Zhe-Xiong Lian; Guanghua Rong; Shinji Shimoda; Kosuke Sumida; M Eric Gershwin
Fine phenotypic and functional characterization of effector cluster of differentiation 8 positive T cells in human patients with primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2011;54(4):1293-302.
2011: Guo-Xiang Yang; Yuehong Wu; Hiroki Tsukamoto; Patrick S C Leung; Zhe-Xiong Lian; Daniel B Rainbow; Kara M Hunter; Gerard A Morris; Paul A Lyons; Laurence B Peterson; Linda S Wicker; M Eric Gershwin; William M Ridgway
CD8 T cells mediate direct biliary ductule damage in nonobese diabetic autoimmune biliary disease.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(2):1259-67.
2011: Yuki Moritoki; Masanobu Tsuda; Koichi tsuneyama; Weici Zhang; Katsunori Yoshida; Zhe-Xiong Lian; Guo-Xiang Yang; William M Ridgway; Linda S Wicker; Aftab A Ansari; M Eric Gershwin
B cells promote hepatic inflammation, biliary cyst formation, and salivary gland inflammation in the NOD.c3c4 model of autoimmune cholangitis.
Cellular immunology 2011;268(1):16-23.
2010: Weici Zhang; Masanobu Tsuda; Guo-Xiang Yang; Koichi tsuneyama; Guanghua Rong; William M Ridgway; Aftab A Ansari; Richard A Flavell; Ross Coppel; Zhe-Xiong Lian; M Eric Gershwin
Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor beta receptor II improves colitis but exacerbates autoimmune cholangitis.
Hepatology (Baltimore, Md.) 2010;52(1):215-22.
2009: Yuki Moritoki; Zhe-Xiong Lian; Keith Lindor; Joseph M Tuscano; Koichi tsuneyama; Weici Zhang; Yoshiyuki Ueno; Robert Dunn; Marilyn Kehry; Ross L Coppel; Ian R Mackay; M Eric Gershwin
B-cell depletion with anti-CD20 ameliorates autoimmune cholangitis but exacerbates colitis in transforming growth factor-beta receptor II dominant negative mice.
Hepatology (Baltimore, Md.) 2009;50(6):1893-903.
2009: Fouad Lafdil; Hua Wang; Ogyi Park; Weici Zhang; Yuki Moritoki; Shi Yin; Xin Yuan Fu; M Eric Gershwin; Zhe-Xiong Lian; Bin Gao
Myeloid STAT3 inhibits T cell-mediated hepatitis by regulating T helper 1 cytokine and interleukin-17 production.
Gastroenterology 2009;137(6):2125-35.e1-2.
2009: Katsunori Yoshida; Guo-Xiang Yang; Weici Zhang; Masanobu Tsuda; Koichi tsuneyama; Yuki Moritoki; Aftab A Ansari; Kazuichi Okazaki; Zhe-Xiong Lian; Ross L Coppel; Ian R Mackay; M Eric Gershwin
Deletion of interleukin-12p40 suppresses autoimmune cholangitis in dominant negative transforming growth factor beta receptor type II mice.
Hepatology (Baltimore, Md.) 2009;50(5):1494-500.
2009: W Zhang; Yuki Moritoki; Koichi tsuneyama; Guo-Xiang Yang; Y Ilan; Zhe-Xiong Lian; M Eric Gershwin
Beta-glucosylceramide ameliorates liver inflammation in murine autoimmune cholangitis.
Clinical and experimental immunology 2009;157(3):359-64.
2009: Yuki Moritoki; Weici Zhang; Koichi tsuneyama; Katsunori Yoshida; Kanji Wakabayashi; Guo-Xiang Yang; Christopher L Bowlus; William M Ridgway; Yoshiyuki Ueno; Aftab A Ansari; Ross Coppel; Ian R Mackay; Richard A Flavell; M Eric Gershwin; Zhe-Xiong Lian
B cells suppress the inflammatory response in a mouse model of primary biliary cirrhosis.
Gastroenterology 2009;136(3):1037-47.
2009: K Wakabayashi; K Yoshida; Patrick S C Leung; Yuki Moritoki; Guo-Xiang Yang; Koichi tsuneyama; Zhe-Xiong Lian; T Hibi; Aftab A Ansari; L S Wicker; William M Ridgway; Ross Coppel; Ian R Mackay; M Eric Gershwin
Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization.
Clinical and experimental immunology 2009;155(3):577-86.
2009: Ruth Y Lan; Thucydides L Salunga; Koichi tsuneyama; Zhe-Xiong Lian; Guo-Xiang Yang; Willy Hsu; Yuki Moritoki; Aftab A Ansari; Claudia Kemper; Jeff Price; John P Atkinson; Ross Coppel; M Eric Gershwin
Hepatic IL-17 responses in human and murine primary biliary cirrhosis.
Journal of autoimmunity 2009;32(1):43-51.
2009: Weici Zhang; Rahul Sharma; Shyr-Te Ju; Xiaosong He; Yanyan Tao; Koichi tsuneyama; Zhigang Tian; Zhe-Xiong Lian; Shu Man Fu; M Eric Gershwin
Deficiency in regulatory T cells results in development of antimitochondrial antibodies and autoimmune cholangitis.
Hepatology (Baltimore, Md.) 2009;49(2):545-52.
2009: Willy Hsu; Weici Zhang; Koichi tsuneyama; Yuki Moritoki; William M Ridgway; Aftab A Ansari; Ross Coppel; Zhe-Xiong Lian; Ian Mackay; M Eric Gershwin
Differential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2Ralpha(-/-) mice.
Hepatology (Baltimore, Md.) 2009;49(1):133-40.
2008: Hua-Xing Wei; Ya-Hui Chuang; Bofeng Li; Haiming Wei; Rui Sun; Yuki Moritoki; M Eric Gershwin; Zhe-Xiong Lian; Zhigang Tian
CD4+ CD25+ Foxp3+ regulatory T cells protect against T cell-mediated fulminant hepatitis in a TGF-beta-dependent manner in mice.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(10):7221-9.
2008: Ming Shi; Yasushi Adachi; Akio Shigematsu; Naoko Koike-Kiriyama; Wei Feng; Seji Yanai; Cui Yunze; Zhe-Xiong Lian; Juan Li; Susumu Ikehara
Intra-bone marrow injection of donor bone marrow cells suspended in collagen gel retains injected cells in bone marrow, resulting in rapid hemopoietic recovery in mice.
Stem cells (Dayton, Ohio) 2008;26(9):2211-6.
2008: Kanji Wakabayashi; Zhe-Xiong Lian; Patrick S C Leung; Yuki Moritoki; Koichi tsuneyama; Mark J Kurth; Kit S Lam; Katsunori Yoshida; Guo-Xiang Yang; Toshifumi Hibi; Aftab A Ansari; William M Ridgway; Ross Coppel; Ian R Mackay; M Eric Gershwin
Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease.
Hepatology (Baltimore, Md.) 2008;48(2):531-40.
2008: Guo-Xiang Yang; Zhe-Xiong Lian; Ya-Hui Chuang; Yuki Moritoki; Ruth Y Lan; Kanji Wakabayashi; Aftab A Ansari; Richard A Flavell; William M Ridgway; Ross Coppel; Koichi tsuneyama; Ian R Mackay; M Eric Gershwin
Adoptive transfer of CD8(+) T cells from transforming growth factor beta receptor type II (dominant negative form) induces autoimmune cholangitis in mice.
Hepatology (Baltimore, Md.) 2008;47(6):1974-82.
2008: Ya-Hui Chuang; Zhe-Xiong Lian; Guo-Xiang Yang; Shang-an Shu; Yuki Moritoki; William M Ridgway; Aftab A Ansari; Mitchell Kronenberg; Richard A Flavell; Bin Gao; M Eric Gershwin
Natural killer T cells exacerbate liver injury in a transforming growth factor beta receptor II dominant-negative mouse model of primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2008;47(2):571-80.
2007: Guo-Xiang Yang; Zhe-Xiong Lian; Ya-Hui Chuang; Shang-an Shu; Yuki Moritoki; Ruth Y Lan; K Wakabayashi; Aftab A Ansari; Kenneth Dorshkind; Susumu Ikehara; M Eric Gershwin
Generation of functionally distinct B lymphocytes from common myeloid progenitors.
Clinical and experimental immunology 2007;150(2):349-57.
2007: Willy Hsu; Shang-an Shu; M Eric Gershwin; Zhe-Xiong Lian
The current immune function of hepatic dendritic cells.
Cellular & molecular immunology 2007;4(5):321-8.
2007: Shang-an Shu; Zhe-Xiong Lian; Ya-Hui Chuang; Guo-Xiang Yang; Yuki Moritoki; Sarah S Comstock; R-Q Zhong; Aftab A Ansari; Yong-Jun Liu; M Eric Gershwin
The role of CD11c(+) hepatic dendritic cells in the induction of innate immune responses.
Clinical and experimental immunology 2007;149(2):335-43.
2007: Chun Zeng; Yu Zhen; Shang-an Shu; Tinghe Wu; Huanfa Yi; Zhe-Xiong Lian; Yong Zhao
The influence of cyclosporin A on lymphocyte attenuator expression.
Journal of autoimmunity 2007;28(4):234-44.
2007: Yuki Moritoki; Zhe-Xiong Lian; Heike Wulff; Guo-Xiang Yang; Ya-Hui Chuang; Ruth Y Lan; Yoshiyuki Ueno; Aftab A Ansari; Ross Coppel; Ian R Mackay; M Eric Gershwin
AMA production in primary biliary cirrhosis is promoted by the TLR9 ligand CpG and suppressed by potassium channel blockers.
Hepatology (Baltimore, Md.) 2007;45(2):314-22.
2007: Tomoyuki Okada; Muneo Inaba; Mitsuru Naiki; Zhe-Xiong Lian; M Eric Gershwin; Susumu Ikehara
Comparative immunobiology of thymic DC mRNA in autoimmune-prone mice.
Journal of autoimmunity 2007;28(1):41-5.
2006: Kanji Wakabayashi; Zhe-Xiong Lian; Yuki Moritoki; Ruth Y Lan; Koichi tsuneyama; Ya-Hui Chuang; Guo-Xiang Yang; William M Ridgway; Yoshiyuki Ueno; Aftab A Ansari; Ross Coppel; Ian R Mackay; M Eric Gershwin
IL-2 receptor alpha(-/-) mice and the development of primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2006;44(5):1240-9.
2006: Yuki Moritoki; Zhe-Xiong Lian; Yoshiyuki Ohsugi; Yoshiyuki Ueno; M Eric Gershwin
B cells and autoimmune liver diseases.
Autoimmunity reviews 2006;5(7):449-57.
2006: Christopher A Aoki; Chaim M Roifman; Zhe-Xiong Lian; Christopher L Bowlus; Gary L Norman; Yehuda Shoenfeld; Ian R Mackay; M Eric Gershwin
IL-2 receptor alpha deficiency and features of primary biliary cirrhosis.
Journal of autoimmunity 2006;27(1):50-3.
2006: Sabine Oertelt; Zhe-Xiong Lian; Chun-Mei Cheng; Ya-Hui Chuang; Kerstien A Padgett; Xiaosong He; William M Ridgway; Aftab A Ansari; Ross Coppel; Ming O Li; Richard A Flavell; Mitchell Kronenberg; Ian R Mackay; M Eric Gershwin
Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1655-60.
2006: Ya-Hui Chuang; Zhe-Xiong Lian; Koichi tsuneyama; Bor-Luen Chiang; Aftab A Ansari; Ross Coppel; M Eric Gershwin
Increased killing activity and decreased cytokine production in NK cells in patients with primary biliary cirrhosis.
Journal of autoimmunity 2006;26(4):232-40.
2006: Ruth Y Lan; Chunmei Cheng; Zhe-Xiong Lian; Koichi tsuneyama; Guo-Xiang Yang; Yuki Moritoki; Ya-Hui Chuang; Takafumi Nakamura; Shigeru Saito; Shinji Shimoda; Atsushi Tanaka; Christopher L Bowlus; Yasuo Takano; Aftab A Ansari; Ross Coppel; M Eric Gershwin
Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2006;43(4):729-37.
2006: Xiaoli Wang; Hiroko Hisha; Shigeru Taketani; Yasushi Adachi; Qing Li; Wenhao Cui; Yunze Cui; Jianfeng Wang; Changye Song; Tomomi Mizokami; Satoshi Okazaki; Qiang Li; Tianxue Fan; Hongxue Fan; Zhe-Xiong Lian; M Eric Gershwin; Susumu Ikehara
Characterization of mesenchymal stem cells isolated from mouse fetal bone marrow.
Stem cells (Dayton, Ohio) 2006;24(3):482-93.
2005: Guo-Xiang Yang; Zhe-Xiong Lian; Kentaro Kikuchi; Yuki Moritoki; Aftab A Ansari; Yong-Jun Liu; Susumu Ikehara; M Eric Gershwin
Plasmacytoid dendritic cells of different origins have distinct characteristics and function: studies of lymphoid progenitors versus myeloid progenitors.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(11):7281-7.
2005: Tin K Mao; Zhe-Xiong Lian; Carlo Selmi; Yasunori Ichiki; Paul Ashwood; Aftab A Ansari; Ross Coppel; Shinji Shimoda; Hiromi Ishibashi; M Eric Gershwin
Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2005;42(4):802-8.
2005: Xiaoli Wang; Hiroko Hisha; Shigeru Taketani; Muneo Inaba; Qiang Li; Wenhao Cui; Changye Song; Tianxue Fan; Yunze Cui; Kequan Guo; Guoxiang Yang; Hongxue Fan; Zhe-Xiong Lian; M Eric Gershwin; Susumu Ikehara
Neural cell adhesion molecule contributes to hemopoiesis-supporting capacity of stromal cell lines.
Stem cells (Dayton, Ohio) 2005;23(9):1389-99.
2005: Ya-Hui Chuang; Zhe-Xiong Lian; Chun-Mei Cheng; Ruth Y Lan; Guo-Xiang Yang; Yuki Moritoki; Bor-Luen Chiang; Aftab A Ansari; Koichi tsuneyama; Ross Coppel; M Eric Gershwin
Increased levels of chemokine receptor CXCR3 and chemokines IP-10 and MIG in patients with primary biliary cirrhosis and their first degree relatives.
Journal of autoimmunity 2005;25(2):126-32.
2005: Ruth Y Lan; Aftab A Ansari; Zhe-Xiong Lian; M Eric Gershwin
Regulatory T cells: development, function and role in autoimmunity.
Autoimmunity reviews 2005;4(6):351-63.
2005: Kentaro Kikuchi; Zhe-Xiong Lian; Yasuhiko Kimura; Carlo Selmi; Guo-Xiang Yang; Stuart Gordon; Pietro Invernizzi; Mauro Podda; Ross Coppel; Aftab A Ansari; Susumu Ikehara; Hiroshi Miyakawa; M Eric Gershwin
Genetic polymorphisms of toll-like receptor 9 influence the immune response to CpG and contribute to hyper-IgM in primary biliary cirrhosis.
Journal of autoimmunity 2005;24(4):347-52.
2005: Guo-Xiang Yang; Zhe-Xiong Lian; Kentaro Kikuchi; Yong-Jun Liu; Aftab A Ansari; Susumu Ikehara; M Eric Gershwin
CD4- plasmacytoid dendritic cells (pDCs) migrate in lymph nodes by CpG inoculation and represent a potent functional subset of pDCs.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3197-203.
2005: Kentaro Kikuchi; Zhe-Xiong Lian; Guo-Xiang Yang; Aftab A Ansari; Susumu Ikehara; Marshall Kaplan; Hiroshi Miyakawa; Ross Coppel; M Eric Gershwin
Bacterial CpG induces hyper-IgM production in CD27(+) memory B cells in primary biliary cirrhosis.
Gastroenterology 2005;128(2):304-12.
2005: Saijai Cheunsuk; Zhe-Xiong Lian; Guo-Xiang Yang; M Eric Gershwin; Jeffrey R Gruen; Christopher L Bowlus
Prss16 is not required for T-cell development.
Molecular and cellular biology 2005;25(2):789-96.
2004: Zhe-Xiong Lian; Kentaro Kikuchi; Guo-Xiang Yang; Aftab A Ansari; Susumu Ikehara; M Eric Gershwin
Expansion of bone marrow IFN-alpha-producing dendritic cells in New Zealand Black (NZB) mice: high level expression of TLR9 and secretion of IFN-alpha in NZB bone marrow.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(8):5283-9.
2003: hiroto kita; Aftab A Ansari; Xiaosong He; Zhe-Xiong Lian; Judith A van de Water; Ross Coppel; Velimir A Luketic; Marshall Kaplan; Hideaki Inamori; Norio Isoda; Kentaro Sugano; Michio Imawari; M Eric Gershwin
Proteasome is required for class I-restricted presentation by Fcgamma receptor-mediated endocytosis in primary biliary cirrhosis.
Journal of autoimmunity 2003;21(2):175-82.
2003: Kentaro Kikuchi; Zhe-Xiong Lian; Xiaosong He; Aftab A Ansari; Miyuki Ishibashi; Hiroshi Miyakawa; Leonard D Shultz; Susumu Ikehara; M Eric Gershwin
Appearance of human plasma cells following differentiation of human B cells in NOD/SCID mouse spleen.
Clinical & developmental immunology 2003;10(2-4):197-202.
2003: Tomoyuki Okada; Zhe-Xiong Lian; Mitsuru Naiki; Aftab A Ansari; Susumu Ikehara; M Eric Gershwin
Murine thymic plasmacytoid dendritic cells.
European journal of immunology 2003;33(4):1012-9.
2003: Zhe-Xiong Lian; Tomoyuki Okada; Xiaosong He; hiroto kita; Yong-Jun Liu; Aftab A Ansari; Kentaro Kikuchi; Susumu Ikehara; M Eric Gershwin
Heterogeneity of dendritic cells in the mouse liver: identification and characterization of four distinct populations.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2323-30.
2003: Junko Toki; Yasushi Adachi; Tienan Jin; Tianxue Fan; Katsunori Takase; Zhe-Xiong Lian; Haruki Hayashi; M Eric Gershwin; Susumu Ikehara
Enhancement of IL-7 following irradiation of fetal thymus.
Immunobiology 2003;207(4):247-58.
2002: Yun-Ze Cui; Hiroko Hisha; Guo-Xiang Yang; Tian-Xue Fan; Tienan Jin; Qing Li; Zhe-Xiong Lian; Susumu Ikehara
Optimal protocol for total body irradiation for allogeneic bone marrow transplantation in mice.
Bone marrow transplantation 2002;30(12):843-9.
2002: Shuji Matsumura; hiroto kita; Xiaosong He; Aftab A Ansari; Zhe-Xiong Lian; Judith A van de Water; Kazuhide Yamamoto; Takao Tsuji; Ross Coppel; Marshall Kaplan; M Eric Gershwin
Comprehensive mapping of HLA-A0201-restricted CD8 T-cell epitopes on PDC-E2 in primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2002;36(5):1125-34.
2002: hiroto kita; Shuji Matsumura; Xiaosong He; Aftab A Ansari; Zhe-Xiong Lian; Judith A van de Water; Ross Coppel; Marshall M Kaplan; M Eric Gershwin
Analysis of TCR antagonism and molecular mimicry of an HLA-A0201-restricted CTL epitope in primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2002;36(4 Pt 1):918-26.
2002: hiroto kita; Shuji Matsumura; Xiaosong He; Aftab A Ansari; Zhe-Xiong Lian; Judith A van de Water; Ross Coppel; Marshall M Kaplan; M Eric Gershwin
Quantitative and functional analysis of PDC-E2-specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis.
The Journal of clinical investigation 2002;109(9):1231-40.
2002: Zhe-Xiong Lian; hiroto kita; Tomoyuki Okada; Tom Hsu; Leonard D Shultz; Kenneth Dorshkind; Aftab A Ansari; Susumu Ikehara; Mitsuru Naiki; M Eric Gershwin
Increased frequency of pre-pro B cells in the bone marrow of New Zealand Black (NZB) mice: implications for a developmental block in B cell differentiation.
Developmental immunology 2002;9(1):35-45.
2002: Tomoyuki Okada; Zhe-Xiong Lian; Tom Hsu; Mitsuru Naiki; Aftab A Ansari; Dan Robinson; Hsing-Jien Kung; Richard Boyd; M Eric Gershwin
Elevated C-met in thymic dendritic cells of New Zealand Black mice.
Developmental immunology 2002;9(1):29-34.
2002: hiroto kita; Zhe-Xiong Lian; Judith A van de Water; Xiaosong He; Shuji Matsumura; Marshall Kaplan; Velimir A Luketic; Ross Coppel; Aftab A Ansari; M Eric Gershwin
Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells.
The Journal of experimental medicine 2002;195(1):113-23.
2002: Zhe-Xiong Lian; Tomoyuki Okada; hiroto kita; Tom Hsu; Leonard D Shultz; Kenneth Dorshkind; Aftab A Ansari; Mitsuru Naiki; Susumu Ikehara; M Eric Gershwin
Age-related alterations in the lymphohematopoietic and B-lineage precursor populations in NZB mice.
Stem cells (Dayton, Ohio) 2002;20(4):293-300.
2002: Guoxiang Yang; Hiroko Hisha; Yunze Cui; Tianxue Fan; Tienan Jin; Qing Li; Zhe-Xiong Lian; Naoki Hosaka; Yulin Li; Susumu Ikehara
A new assay method for late CFU-S formation and long-term reconstituting activity using a small number of pluripotent hemopoietic stem cells.
Stem cells (Dayton, Ohio) 2002;20(3):241-8.
2001: Tienan Jin; Junko Toki; Muneo Inaba; Kikuya Sugiura; Tianxue Fan; C Yu; Zhe-Xiong Lian; K Takase; B Feng; Tomoki Ito; Yunze Cui; Guoxiang Yang; Susumu Ikehara
A novel strategy for organ allografts using sublethal (7 Gy) irradiation followed by injection of donor bone marrow cells via portal vein.
Transplantation 2001;71(12):1725-31.
2001: Tian-Xue Fan; Hiroko Hisha; T N Jin; C Z Yu; Zhe-Xiong Lian; S B Guo; Yun-Ze Cui; B Feng; Guo-Xiang Yang; Qing Li; Susumu Ikehara
Successful allogeneic bone marrow transplantation (BMT) by injection of bone marrow cells via portal vein: stromal cells as BMT-facilitating cells.
Stem cells (Dayton, Ohio) 2001;19(2):144-50.
2000: Y Li; Hiroko Hisha; M Inaba; Zhe-Xiong Lian; C Yu; M Kawamura; Y Yamamoto; N Nishio; Junko Toki; Hongxue Fan; Susumu Ikehara
Evidence for migration of donor bone marrow stromal cells into recipient thymus after bone marrow transplantation plus bone grafts: A role of stromal cells in positive selection.
Experimental hematology 2000;28(8):950-60.
2000: B Feng; Muneo Inaba; Zhe-Xiong Lian; Yunze Cui; Junko Toki; Tomoki Ito; Tienan Jin; Tianxue Fan; Guoxiang Yang; C Yu; Taketoshi Kushida; Susumu Ikehara
Development of mouse dendritic cells from lineage-negative c-kit(low) pluripotent hemopoietic stem cells in vitro.
Stem cells (Dayton, Ohio) 2000;18(1):53-60.
1999: Zhe-Xiong Lian; B Feng; Kikuya Sugiura; Muneo Inaba; C Yu; Tienan Jin; Tianxue Fan; Yunze Cui; Ryoji Yasumizu; Junko Toki; Yashusi Adachi; Hiroko Hisha; Susumu Ikehara
c-kit
Stem cells (Dayton, Ohio) 1999;17(1):39-44.

1998: H Morita; K Sugiura; Muneo Inaba; Tienan Jin; J Ishikawa; Zhe-Xiong Lian; Yashusi Adachi; S Sogo; K Yamanishi; H Taki; M Adachi; T Noumi; Y Kamiyama; R A Good; Susumu Ikehara
A strategy for organ allografts without using immunosuppressants or irradiation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6947-52.
1998: C Z Yu; Hiroko Hisha; Yongan Li; Zhe-Xiong Lian; T Nishino; Junko Toki; Yashusi Adachi; Muneo Inaba; Tian-Xue Fan; Tienan Jin; T Iguchi; S Sogo; Naoki Hosaka; T H Song; J Xing; Susumu Ikehara
Stimulatory effects of hepatocyte growth factor on hemopoiesis of SCF/c-kit system-deficient mice.
Stem cells (Dayton, Ohio) 1998;16(1):66-77.
1997: H Hayashi; Junko Toki; Zhe-Xiong Lian; Kyoichi Inoue; Susumu Ikehara
Analyses of extrathymic T cell differentiation in nu/nu mice by grafting embryonal organs.
Immunobiology 1997;197(1):1-15.
1997: Zhe-Xiong Lian; Junko Toki; C Yu; H Hayashi; Ryoji Yasumizu; Kikuya Sugiura; Tienan Jin; Muneo Inaba; Hiroko Hisha; Yongan Li; W Yu; Hongxue Fan; Susumu Ikehara
Intrathymically injected hemopoietic stem cells can differentiate into all lineage cells in the thymus: differences between c-kit+ cells and c-kit < low cells.
Stem cells (Dayton, Ohio) 1997;15(6):430-6.
1994: Y Zhang; Ryoji Yasumizu; Kikuya Sugiura; F Hashimoto; Yasuo Amoh; Zhe-Xiong Lian; N Nishio; Susumu Ikehara
Fate of allogeneic or syngeneic cells in intravenous or portal vein injection: possible explanation for the mechanism of tolerance induction by portal vein injection.
European journal of immunology 1994;24(7):1558-65.