NELLY KIEFFER

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E Schaffner-Reckinger; A Salsmann; N Debili; J Bellis; J De Mey; W Vainchenker; W H Ouwehand; N Kieffer
Overexpression of the partially activated alpha(IIb)beta3D723H integrin salt bridge mutant downregulates RhoA activity and induces microtubule-dependent proplatelet-like extensions in Chinese hamster ovary cells.
Karen Vanhoorelbeke; Simon F De Meyer; Inge Pareyn; Chantal Melchior; Sebastien Plançon; Christiane Margue; Olivier Pradier; Pierre Fondu; Nelly Kieffer; Timothy A Springer; et al.
The novel S527F mutation in the integrin beta3 chain induces a high affinity alphaIIbbeta3 receptor by hindering adoption of the bent conformation.
Sophie Rodius; Olivier Chaloin; Michèle Moes; Elisabeth Schaffner-Reckinger; Isabelle Landrieu; Guy Lippens; Minghui Lin; Ji Zhang; Nelly Kieffer
The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges.

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All Publications

2009: E Schaffner-Reckinger; A Salsmann; N Debili; J Bellis; J De Mey; W Vainchenker; W H Ouwehand; N Kieffer
Overexpression of the partially activated alpha(IIb)beta3D723H integrin salt bridge mutant downregulates RhoA activity and induces microtubule-dependent proplatelet-like extensions in Chinese hamster ovary cells.
Journal of thrombosis and haemostasis : JTH 2009;7(7):1207-17.
2009: Karen Vanhoorelbeke; Simon F De Meyer; Inge Pareyn; Chantal Melchior; Sebastien Plançon; Christiane Margue; Olivier Pradier; Pierre Fondu; Nelly Kieffer; Timothy A Springer; et al.
The novel S527F mutation in the integrin beta3 chain induces a high affinity alphaIIbbeta3 receptor by hindering adoption of the bent conformation.
The Journal of biological chemistry 2009;284(22):14914-20.
2008: Sophie Rodius; Olivier Chaloin; Michèle Moes; Elisabeth Schaffner-Reckinger; Isabelle Landrieu; Guy Lippens; Minghui Lin; Ji Zhang; Nelly Kieffer
The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges.
The Journal of biological chemistry 2008;283(35):24212-23.
2008: Xiaoyu Su; Jianqing Mi; Jinsong Yan; Panagiotis Flevaris; Yuanjing Lu; Hongchen Liu; Zheng Ruan; Xuefeng Wang; Nelly Kieffer; Saijuan Chen; et al.
RGT, a synthetic peptide corresponding to the integrin beta 3 cytoplasmic C-terminal sequence, selectively inhibits outside-in signaling in human platelets by disrupting the interaction of integrin alpha IIb beta 3 with Src kinase.
Blood 2008;112(3):592-602.
2008: Cedric Ghevaert; Alexandre Salsmann; Nicholas A Watkins; Elisabeth Schaffner-Reckinger; Angela Rankin; Stephen F Garner; Jonathan Stephens; Graham A Smith; Najet Debili; William Vainchenker; et al.
A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the alphaIIbbeta3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia.
Blood 2008;111(7):3407-14.
2008: René Scheiden; Tom Hein; Catherine Wagener; Nelly Kieffer; Stanislas Lamy; Catherine Capesius
Testicular cancer in Luxembourg: incidence and outcome in relation to the different histo-pathological types (1980-2004).
Bulletin de la Société des sciences médicales du Grand-Duché de Luxembourg 2008;(4):521-39.
2008: Sallouha Aidoudi; Kinga Bujakowska; Nelly Kieffer; Andreas Bikfalvi
The CXC-chemokine CXCL4 interacts with integrins implicated in angiogenesis.
PloS one 2008;3(7):e2657.
2007: Michèle Moes; Sophie Rodius; Stacey J Coleman; Susan J Monkley; Erik Goormaghtigh; Laurent Tremuth; Corinne Kox; Patrick P G van der Holst; David R Critchley; Nelly Kieffer
The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton.
The Journal of biological chemistry 2007;282(23):17280-8.
2007: Martine Schmitz; Gérard Grignard; Christiane Margue; Walter Dippel; Catherine Capesius; Joël Mossong; Michel Nathan; Sandro Giacchi; René Scheiden; Nelly Kieffer
Complete loss of PTEN expression as a possible early prognostic marker for prostate cancer metastasis.
International journal of cancer. Journal international du cancer 2007;120(6):1284-92.
2006: Dario Caronzolo; Valeria Lucini; Marilou Pannacci; Silvia Grosso; Nelly Kieffer; Lorenzo Bello; Andreas Bikfalvi; Francesco Scaglione
Effect of PEX, a noncatalytic metalloproteinase fragment with integrin-binding activity, on experimental Chlamydophila pneumoniae infection.
Antimicrobial agents and chemotherapy 2006;50(10):3277-82.
2006: Alexandre Salsmann; Elisabeth Schaffner-Reckinger; Nelly Kieffer
RGD, the Rho'd to cell spreading.
European journal of cell biology 2006;85(3-4):249-54.
2006: Nelly Kieffer; Martine Schmitz; René Scheiden; Michel Nathan; Jean-Claude Faber
Involvement of the RNAse L gene in prostate cancer.
Bulletin de la Société des sciences médicales du Grand-Duché de Luxembourg 2006;(1):21-8.
2006: René Scheiden; Marc Keipes; Carlo Bock; Walter Dippel; Nelly Kieffer; Catherine Capesius
Thyroid cancer in Luxembourg: a national population-based data report (1983-1999).
BMC cancer 2006;6():102.
2006: P Legendre; A Salsmann; J Rayes; O Trassard; N Kieffer; D Baruch
CHO cells expressing the high affinity alpha(IIb)beta3 T562N integrin demonstrate enhanced adhesion under shear.
Journal of thrombosis and haemostasis : JTH 2006;4(1):236-46.
2005: Alexandre Salsmann; Elisabeth Schaffner-Reckinger; Fabrice Kabile; Sébastien Plançon; Nelly Kieffer
A new functional role of the fibrinogen RGD motif as the molecular switch that selectively triggers integrin alphaIIbbeta3-dependent RhoA activation during cell spreading.
The Journal of biological chemistry 2005;280(39):33610-9.
2005: Andrew Smith; Yolanda R Carrasco; Paula Stanley; Nelly Kieffer; Facundo D Batista; Nancy Hogg
A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes.
The Journal of cell biology 2005;170(1):141-51.
2005: Nelly Kieffer; Martine Schmitz; Sébastien Plançon; Christiane Margue; Fanny Huselstein; Gérard Grignard; Walter Dippel; Michel Nathan; Sandro Giacchi; René Scheiden
ILK as a potential marker gene to ascertain specific adenocarcinoma cell mRNA isolation from frozen prostate biopsy tissue sections.
International journal of oncology 2005;26(6):1549-58.
2005: Stephanie Kreis; Hans-Joachim Schönfeld; Chantal Melchior; Beat Steiner; Nelly Kieffer
The intermediate filament protein vimentin binds specifically to a recombinant integrin alpha2/beta1 cytoplasmic tail complex and co-localizes with native alpha2/beta1 in endothelial cell focal adhesions.
Experimental cell research 2005;305(1):110-21.
2005: René Scheiden; Paul Pescatore; Yolande Wagener; Nelly Kieffer; Catherine Capesius
Colon cancer in Luxembourg: a national population-based data report, 1988-1998.
BMC cancer 2005;5():52.
2004: Patricia Hermand; Pierre Gane; Isabelle Callebaut; Nelly Kieffer; Jean-Pierre Cartron; Pascal Bailly
Integrin receptor specificity for human red cell ICAM-4 ligand. Critical residues for alphaIIbeta3 binding.
European journal of biochemistry / FEBS 2004;271(18):3729-40.
2004: Laurent Tremuth; Stephanie Kreis; Chantal Melchior; Johan Hoebeke; Philippe Rondé; Sébastien Plançon; Kenneth Takeda; Nelly Kieffer
A fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain.
The Journal of biological chemistry 2004;279(21):22258-66.
2004: Grégory Giannone; Benjamin J Dubin-Thaler; Hans-Günther Döbereiner; Nelly Kieffer; Anne R Bresnick; Michael P Sheetz
Periodic lamellipodial contractions correlate with rearward actin waves.
Cell 2004;116(3):431-43.
2003: Christophe Dubois; Beat Steiner; Nelly Kieffer; Sylvie C Meyer Reigner
Thrombin binding to GPIbalpha induces platelet aggregation and fibrin clot retraction supported by resting alphaIIbbeta3 interaction with polymerized fibrin.
Thrombosis and haemostasis 2003;89(5):853-65.
2002: Médina Mekrache; Paulette Legendre; Nelly Kieffer; Dominique Baruch
Activation of integrin alphaIIbbeta3 expressed in Chinese hamster ovary cells is required for interaction with solid-phase von Willebrand factor.
British journal of haematology 2002;119(4):1024-32.
2002: Emmanuel Laplantine; Patrik Maurer; Laurent Vallar; Johannes Eble; Mats Paulsson; Peter Bruckner; Nelly Kieffer; Monique Aumailley
The integrin beta1 subunit cytoplasmic tail forms oligomers: a potential role in beta1 integrin clustering.
Biology of the cell / under the auspices of the European Cell Biology Organization 2002;94(6):375-87.
2002: Isabelle Pécheur; Olivier Peyruchaud; Claire-Marie Serre; Julien Guglielmi; Carole Voland; Francois Bourre; Christiane Margue; Martine Cohen-Solal; Annie Buffet; Nelly Kieffer; et al.
Integrin alpha(v)beta3 expression confers on tumor cells a greater propensity to metastasize to bone.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(10):1266-8.
2002: Chantal Melchior; Stephanie Kreis; Bassam Janji; Nelly Kieffer
Promoter characterization and genomic organization of the gene encoding integrin-linked kinase 1.
Biochimica et biophysica acta 2002;1575(1-3):117-22.
2002: Nicholas A Watkins; Elisabeth Schaffner-Reckinger; David L Allen; Graham J Howkins; Nicolaas H C Brons; Graham A Smith; Paul Metcalfe; Michael F Murphy; Nelly Kieffer; Willem H Ouwehand
HPA-1a phenotype-genotype discrepancy reveals a naturally occurring Arg93Gln substitution in the platelet beta 3 integrin that disrupts the HPA-1a epitope.
Blood 2002;99(5):1833-9.
2002: Médina Mekrache; Nelly Kieffer; Dominique Baruch
Activation of recombinant alphaIIbbeta3 expressed in Chinese hamster ovary cells exposes different binding sites for fibrinogen or von Willebrand factor: evidence using monoclonal antibodies to alphaIIbbeta3.
British journal of haematology 2002;116(3):636-44.
2001: M C Morel-Kopp; C Melchior; P Chen; W Ammerlaan; T Lecompte; C Kaplan; N Kieffer
A naturally occurring point mutation in the beta3 integrin MIDAS-like domain affects differently alphavbeta3 and alphaIIIbbeta3 receptor function.
Thrombosis and haemostasis 2001;86(6):1425-34.
2001: P Chen; C Melchior; N H Brons; N Schlegel; J Caen; N Kieffer
Probing conformational changes in the I-like domain and the cysteine-rich repeat of human beta 3 integrins following disulfide bond disruption by cysteine mutations: identification of cysteine 598 involved in alphaIIbbeta3 activation.
The Journal of biological chemistry 2001;276(42):38628-35.
2001: S Plançon; M C Morel-Kopp; E Schaffner-Reckinger; P Chen; N Kieffer
Green fluorescent protein (GFP) tagged to the cytoplasmic tail of alphaIIb or beta3 allows the expression of a fully functional integrin alphaIIb(beta3): effect of beta3GFP on alphaIIb(beta3) ligand binding.
The Biochemical journal 2001;357(Pt 2):529-36.
2001: E Schaffner-Reckinger; N H Brons; N Kieffer
Evidence from site-directed mutagenesis that the cytoplasmic domain of the beta3 subunit influences the conformational state of the alphaVbeta3 integrin ectodomain.
Thrombosis and haemostasis 2001;85(4):716-23.
2001: G Kasper; A Brown; M Eberl; L Vallar; N Kieffer; C Berry; K Girdwood; P Eggleton; R Quinnell; D I Pritchard
A calreticulin-like molecule from the human hookworm Necator americanus interacts with C1q and the cytoplasmic signalling domains of some integrins.
Parasite immunology 2001;23(3):141-52.
2000: S Pasco; J C Monboisse; N Kieffer
The alpha 3(IV)185-206 peptide from noncollagenous domain 1 of type IV collagen interacts with a novel binding site on the beta 3 subunit of integrin alpha Vbeta 3 and stimulates focal adhesion kinase and phosphatidylinositol 3-kinase phosphorylation.
The Journal of biological chemistry 2000;275(42):32999-3007.
2000: B Janji; C Melchior; L Vallar; N Kieffer
Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-beta1 stimulation.
Oncogene 2000;19(27):3069-77.
2000: E Laplantine; L Vallar; K Mann; N Kieffer; M Aumailley
Interaction between the cytodomains of the alpha 3 and beta 1 integrin subunits regulates remodelling of adhesion complexes on laminin.
Journal of cell science 2000;113 ( Pt 7)():1167-76.
1999: B Janji; C Melchior; V Gouon; L Vallar; N Kieffer
Autocrine TGF-beta-regulated expression of adhesion receptors and integrin-linked kinase in HT-144 melanoma cells correlates with their metastatic phenotype.
International journal of cancer. Journal international du cancer 1999;83(2):255-62.
1999: L Vallar; C Melchior; S Plançon; H Drobecq; G Lippens; V Regnault; N Kieffer
Divalent cations differentially regulate integrin alphaIIb cytoplasmic tail binding to beta3 and to calcium- and integrin-binding protein.
The Journal of biological chemistry 1999;274(24):17257-66.
1998: O Peyruchaud; A T Nurden; S Milet; L Macchi; A Pannochia; P F Bray; N Kieffer; F Bourre
R to Q amino acid substitution in the GFFKR sequence of the cytoplasmic domain of the integrin IIb subunit in a patient with a Glanzmann's thrombasthenia-like syndrome.
Blood 1998;92(11):4178-87.
1998: E Schaffner-Reckinger; V Gouon; C Melchior; S Plançon; N Kieffer
Distinct involvement of beta3 integrin cytoplasmic domain tyrosine residues 747 and 759 in integrin-mediated cytoskeletal assembly and phosphotyrosine signaling.
The Journal of biological chemistry 1998;273(20):12623-32.
1998: C Perrault; M Mekrache; D Schoevaert; N Kieffer; C Melchior; J Warszawski; D Baruch
Ser752 mutation to Pro or Ala in the beta3 integrin subunit differentially affects the kinetics of cell spreading to von Willebrand factor and fibrinogen.
Cell adhesion and communication 1998;6(4):335-48.
1997: M C Morel-Kopp; C Kaplan; V Proulle; V Jallu; C Melchior; O Peyruchaud; M H Aurousseau; N Kieffer
A three amino acid deletion in glycoprotein IIIa is responsible for type I Glanzmann's thrombasthenia: importance of residues Ile325Pro326Gly327 for beta3 integrin subunit association.
Blood 1997;90(2):669-77.
1997: M Si-Tahar; D Pidard; V Balloy; M Moniatte; N Kieffer; A Van Dorsselaer; M Chignard
Human neutrophil elastase proteolytically activates the platelet integrin alphaIIbbeta3 through cleavage of the carboxyl terminus of the alphaIIb subunit heavy chain. Involvement in the potentiation of platelet aggregation.
The Journal of biological chemistry 1997;272(17):11636-47.
1996: V Gouon; G C Tucker; L Kraus-Berthier; G Atassi; N Kieffer
Up-regulated expression of the beta3 integrin and the 92-kDa gelatinase in human HT-144 melanoma cell tumors grown in nude mice.
International journal of cancer. Journal international du cancer 1996;68(5):650-62.
1996: D Gironcel; C Racaud-Sultan; B Payrastre; M Haricot; G Borchert; N Kieffer; M Breton; H Chap
alphaIIb beta 3-integrin mediated adhesion of human platelets to a fibrinogen matrix triggers phospholipase C activation and phosphatidylinositol 3',4'-biphosphate accumulation.
FEBS letters 1996;389(3):253-6.
1996: N Kieffer; C Melchior; J M Guinet; S Michels; V Gouon; N Bron
Serine 752 in the cytoplasmic domain of the beta 3 integrin subunit is not required for alpha v beta 3 postreceptor signaling events.
Cell adhesion and communication 1996;4(1):25-39.
1994: J Williams; N Kieffer
Adhesion molecules in cellular interactions.
Trends in cell biology 1994;4(3):102-4.
1993: J L Fauchère; A D Morris; C Thurieau; S Simonet; T J Verbeuren; N Kieffer
Modulation of the activity and assessment of the receptor selectivity in a series of new RGD-containing peptides.
International journal of peptide and protein research 1993;42(5):440-4.
1992: J Enouf; R Bredoux; B Papp; I Djaffar; A M Lompré; N Kieffer; O Gayet; K Clemetson; F Wuytack; J P Rosa
Human platelets express the SERCA2-b isoform of Ca(2+)-transport ATPase.
The Biochemical journal 1992;286 ( Pt 1)():135-40.
1992: N Kieffer; J Guichard; J Breton-Gorius
Dynamic redistribution of major platelet surface receptors after contact-induced platelet activation and spreading. An immunoelectron microscopy study.
The American journal of pathology 1992;140(1):57-73.
1991: F Lanza; D Wolf; C F Fox; N Kieffer; J M Seyer; V A Fried; S R Coughlin; D R Phillips; L K Jennings
cDNA cloning and expression of platelet p24/CD9. Evidence for a new family of multiple membrane-spanning proteins.
The Journal of biological chemistry 1991;266(16):10638-45.
1991: N Kieffer; L A Fitzgerald; D Wolf; D A Cheresh; D R Phillips
Adhesive properties of the beta 3 integrins: comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cells.
The Journal of cell biology 1991;113(2):451-61.
1991: A Darnanville; R Bredoux; K J Clemetson; N Kieffer; N Bourdeau; S Levy-Toledano; J P Caen; J Enouf
The phosphoprotein that regulates platelet Ca2+ transport is located on the plasma membrane, controls membrane-associated Ca2(+)-ATPase and is not glycoprotein Ib beta-subunit.
The Biochemical journal 1991;273(Pt 2)():429-34.
1990: F Lanza; N Kieffer; D R Phillips; L A Fitzgerald
Characterization of the human platelet glycoprotein IIIa gene. Comparison with the fibronectin receptor beta-subunit gene.
The Journal of biological chemistry 1990;265(30):18098-103.
1990: N Debili; N Kieffer; M Nakazawa; J Guichard; M Titeux; E Cramer; J Breton-Gorius; W Vainchenker
Expression of platelet glycoprotein Ib by cultured human megakaryocytes: ultrastructural localization and biosynthesis.
Blood 1990;76(2):368-76.
1990: J C Lewis; R R Hantgan; S C Stevenson; T Thornburg; N Kieffer; J Guichard; J Breton-Gorius
Fibrinogen and glycoprotein IIb/IIIa localization during platelet adhesion. Localization to the granulomere and at sites of platelet interaction.
The American journal of pathology 1990;136(1):239-52.
1990: N Kieffer; D R Phillips
Platelet membrane glycoproteins: functions in cellular interactions.
Annual review of cell biology 1990;6():329-57.
1990: K J Clemetson; R H Wenger; A N Wicki; J M Clemetson; N Kieffer; J Drouin
Molecular biology of human platelet membrane glycoprotein Ib.
Progress in clinical and biological research 1990;356():77-88.
1989: R H Wenger; A N Wicki; N Kieffer; S Adolph; H Hameister; K J Clemetson
The 5' flanking region and chromosomal localization of the gene encoding human platelet membrane glycoprotein Ib alpha.
Gene 1989;85(2):517-24.
1989: N Kieffer; A Bettaieb; C Legrand; L Coulombel; W Vainchenker; L Edelman; J Breton-Gorius
Developmentally regulated expression of a 78 kDa erythroblast membrane glycoprotein immunologically related to the platelet thrombospondin receptor.
The Biochemical journal 1989;262(3):835-42.
1989: N Debili; N Kieffer; M T Mitjavila; J L Villeval; J Guichard; F Teillet; A Henri; K J Clemetson; W Vainchenker; J Breton-Gorius
Expression of platelet glycoproteins by erythroid blasts in four cases of trisomy 21.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1989;3(9):669-78.
1989: R H Wenger; A N Wicki; A Walz; N Kieffer; K J Clemetson
Cloning of cDNA coding for connective tissue activating peptide III from a human platelet-derived lambda gt11 expression library.
Blood 1989;73(6):1498-503.
1989: J Breton-Gorius; J L Villeval; N Kieffer; M T Mitjavila; J Guichard; W Vainchenker
Limits of phenotypic markers for the diagnosis of megakaryoblastic leukemia.
Blood cells 1989;15(1):259-77.
1988: N Kieffer; A T Nurden; M Hasitz; M Titeux; J Breton-Gorius
Identification of platelet membrane thrombospondin binding molecules using an anti-thrombospondin antibody.
Biochimica et biophysica acta 1988;967(3):408-15.
1988: F Farace; M T Mitjavila; A Betaieb; M C Dokhelar; J Wiels; Y Finale; N Kieffer; J Breton-Gorius; W Vainchenker; T Tursz
New hematopoietic differentiation antigens detected by anti-K562 monoclonal antibodies.
Cancer research 1988;48(20):5759-65.
1988: R H Wenger; N Kieffer; A N Wicki; K J Clemetson
Structure of the human blood platelet membrane glycoprotein Ib alpha gene.
Biochemical and biophysical research communications 1988;156(1):389-95.
1988: N Kieffer; J L Wautier; L Coulombel; M Titeux; M P Wautier; W Vainchenker; C Ruan; J Breton-Gorius
Uncoupling in the expression of platelet GP IIb/IIIa in human endothelial cells and K562 cells: absence of immunologic crossreactivity between platelet GP IIb and the vitronectin receptor alpha chain.
Blood 1988;72(4):1209-15.
1988: K C Gatter; J L Cordell; H Turley; A Heryet; N Kieffer; D J Anstee; D Y Mason
The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens.
Histopathology 1988;13(3):257-67.
1988: W Vainchenker; N Kieffer
Human megakaryocytopoiesis: in vitro regulation and characterization of megakaryocytic precursor cells by differentiation markers.
Blood reviews 1988;2(2):102-7.
1988: A Bettaieb; F Farace; M T Mitjavila; Z Mishal; M C Dokhelar; T Tursz; J Breton-Gorius; W Vainchenker; N Kieffer
Use of a monoclonal antibody (GA3) to demonstrate lineage restricted O-glycosylation on leukosialin during terminal erythroid differentiation.
Blood 1988;71(5):1226-33.
1988: C Legrand; V Dubernard; N Kieffer; A T Nurden
Use of a monoclonal antibody to measure the surface expression of thrombospondin following platelet activation.
European journal of biochemistry / FEBS 1988;171(1-2):393-9.
1988: M T Mitjavila; G Vinci; J L Villeval; N Kieffer; A Henri; U Testa; J Breton-Gorius; W Vainchenker
Human platelet alpha granules contain a nonspecific inhibitor of megakaryocyte colony formation: its relationship to type beta transforming growth factor (TGF-beta).
Journal of cellular physiology 1988;134(1):93-100.
1988: D Blanchard; N Kieffer; A T Nurden; J P Cartron
Structural modifications of platelet membrane glycoprotein GPIb in the Tn syndrome.
Current studies in hematology and blood transfusion 1988;(55):45-52.
1988: P Bierling; P Fromont; A Elbez; N Duedari; N Kieffer
Early immunization against platelet glycoprotein IIIa in a newborn Glanzmann type I patient.
Vox sanguinis 1988;55(2):109-13.
1987: A Bettaieb; J L Villeval; N Kieffer; F Farace; L Edelman; J P Cartron; W Vainchenker
Early erythroid markers as probes for normal and leukaemic erythroid differentiation.
Annales de l'Institut Pasteur. Immunology 1987;138(6):877-83.
1987: N Kieffer; J Guichard; J P Farcet; W Vainchenker; J Breton-Gorius
Biosynthesis of major platelet proteins in human blood platelets.
European journal of biochemistry / FEBS 1987;164(1):189-95.
1987: J Breton-Gorius; J C Lewis; J Guichard; N Kieffer; W Vainchenker
Monoclonal antibodies specific for human platelet membrane glycoproteins bind to monocytes by focal absorption of platelet membrane fragments: an ultrastructural immunogold study.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1987;1(2):131-41.
1986: N Kieffer; N Debili; A Wicki; M Titeux; A Henri; Z Mishal; J Breton-Gorius; W Vainchenker; K J Clemetson
Expression of platelet glycoprotein Ib alpha in HEL cells.
The Journal of biological chemistry 1986;261(34):15854-62.
1986: F Farace; N Kieffer; B Caillou; W Vainchenker; T Tursz; M C Dokhelar
A 93-kDa glycoprotein expressed on human cultured monocytes and dendritic reticulum cells defined by an anti-K562 monoclonal antibody.
European journal of immunology 1986;16(12):1521-6.
1986: J N George; E B Pickett; S Saucerman; R P McEver; T J Kunicki; N Kieffer; P J Newman
Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery.
The Journal of clinical investigation 1986;78(2):340-8.
1986: W Vainchenker; N Kieffer; E Cramer; G Vinci; N Debili; A Henri; M Titeux; J Guichard; Z Mishal; J Breton-Gorius
Expression of platelet proteins during maturation of human megakaryocytes and of the K 562/HEL cell lines.
Progress in clinical and biological research 1986;215():227-40.
1985: S Niewiarowski; E Kornecki; D Hershock; G P Tuszynski; J S Bennett; C Soria; J Soria; F Dunn; D Pidard; N Kieffer
Aggregation of chymotrypsin-treated thrombasthenic platelets is mediated by fibrinogen binding to glycoproteins IIb and IIIa.
The Journal of laboratory and clinical medicine 1985;106(6):651-60.
1985: A T Nurden; D Didry; N Kieffer; R P McEver
Residual amounts of glycoproteins IIb and IIIa may be present in the platelets of most patients with Glanzmann's thrombasthenia.
Blood 1985;65(4):1021-4.
1984: J P Rosa; N Kieffer; D Didry; D Pidard; T J Kunicki; A T Nurden
The human platelet membrane glycoprotein complex GP IIb-IIIa expresses antigenic sites not exposed on the dissociated glycoproteins.
Blood 1984;64(6):1246-53.
1984: N Kieffer; B Boizard; D Didry; J L Wautier; A T Nurden
Immunochemical characterization of the platelet-specific alloantigen Leka: a comparative study with the PlA1 alloantigen.
Blood 1984;64(6):1212-9.
1984: M D Kazatchkine; C R Lambré; N Kieffer; F Maillet; A T Nurden
Membrane-bound hemagglutinin mediates antibody and complement-dependent lysis of influenza virus-treated human platelets in autologous serum.
The Journal of clinical investigation 1984;74(3):976-84.
1984: A Tabilio; J P Rosa; U Testa; N Kieffer; A T Nurden; M C Del Canizo; J Breton-Gorius; W Vainchenker
Expression of platelet membrane glycoproteins and alpha-granule proteins by a human erythroleukemia cell line (HEL).
The EMBO journal 1984;3(2):453-9.