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Yong Shen

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Fa-Jing Liu; Yong Shen; Jia-Xin Xu; Yi Chai; Wei Du; Peng Zhang
Posterior decompression with transforaminal interbody fusion for thoracic myelopathy due to ossification of the posterior longitudinal ligament and the ligamentum flavum at the same level.
Wei Zhang; Ying-ze Zhang; Zeng-jiang Zhen; Hui-wang Wang; Yun-xia Wang; Da-long Yang; Yong Shen
In vitro osteoclast-suppressing effect of sodium ibandronate.
Canghai Shen; Yong Shen; Yingze Zhang; Wenyuan Ding; Junming Cao
[Contrastive analysis of neck axial symptoms after hybrid surgery or traditional anterior cervical discectomy and fusion for treatment of two-level cervical disease].

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2013: Fa-Jing Liu; Yong Shen; Jia-Xin Xu; Yi Chai; Wei Du; Peng Zhang
Posterior decompression with transforaminal interbody fusion for thoracic myelopathy due to ossification of the posterior longitudinal ligament and the ligamentum flavum at the same level.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2013;20(4):570-5.
2013: Wei Zhang; Ying-ze Zhang; Zeng-jiang Zhen; Hui-wang Wang; Yun-xia Wang; Da-long Yang; Yong Shen
In vitro osteoclast-suppressing effect of sodium ibandronate.
Chinese medical journal 2013;126(4):751-5.
2013: Canghai Shen; Yong Shen; Yingze Zhang; Wenyuan Ding; Junming Cao
[Contrastive analysis of neck axial symptoms after hybrid surgery or traditional anterior cervical discectomy and fusion for treatment of two-level cervical disease].
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 2013;27(1):58-61.
2012: Dong-xiao Xie; Jia-xin Xu; Da-long Yang; Wen-yuan Ding; Yong Shen; Ya-peng Sun; Ying-ze Zhang; Feng Zhang
[Radiological comparison of bilateral paravertebral muscles in degenerative lumbar scoliosis and its potential importance].
Zhonghua wai ke za zhi [Chinese journal of surgery] 2012;50(11):975-80.
2012: Fa-jing Liu; Hu Ren; Yong Shen; Wen-yuan Ding; Lin-feng Wang
Pulmonary embolism caused by cement leakage after percutaneous kyphoplasty: a case report.
Orthopaedic surgery 2012;4(4):263-5.
2012: Tao Lei; Jun-Ming Cao; Wen-Yuan Ding; Yong Shen; Lin-Feng Wang; Qing-Hua Ma
Cerebrospinal fluid leakage during anterior approach cervical spine surgery for severe ossification of the posterior longitudinal ligament: prevention and treatment.
Orthopaedic surgery 2012;4(4):247-52.
2012: Hui Wang; Lin-feng Wang; Da-long Yang; Wei Zhang; Ying-ze Zhang; Lai-zhen Cao; Wen-yuan Ding; Yong Shen; Ya-peng Sun; Lei Ma
[Analysis of axial symptoms after indirect decompression for ossification of the posterior longitudinal ligament of the cervical spine].
Zhonghua wai ke za zhi [Chinese journal of surgery] 2012;50(7):601-6.
2012: Jun-Ming Cao; Wen-Yuan Ding; Hu Ren; Yong Shen; Yan-Ling Su; Da-Long Yang; Ying-ze Zhang; Di Zhang
Selection of operative approaches for multilevel cervical spondylotic myelopathy by imageological score.
Journal of spinal disorders & techniques 2012;25(2):99-106.
2011: Wen-Yuan Ding; Lai-Zhen Cao; Ya-Peng Sun; Jia-Xin Xu; Da-Long Yang; Wei Zhang; Ying-ze Zhang; Yong Shen
Intervertebral disc degeneration and bone density in degenerative lumbar scoliosis: a comparative study between patients with degenerative lumbar scoliosis and patients with lumbar stenosis.
Chinese medical journal 2011;124(23):3875-8.
2011: Wen-yuan Ding; Jin-ku Guo; Bao-jun Li; Yong Shen; Ya-peng Sun; Hai-long Wu; Wei Zhang; Lai-zhen Cao
[Correlation between intervertebral disc-endplate degeneration and bony structural parameter in adult degerative scoliosis and its significance].
Zhonghua wai ke za zhi [Chinese journal of surgery] 2011;49(12):1123-7.
2011: Da-long Yang; Ying-ze Zhang; Yong Shen; Jun-ming Cao
Surgical management of cervical cord injury with ossification of the cervical posterior longitudinal ligament.
Orthopaedic surgery 2011;3(2):95-101.
2011: N Gubergrits; E Malecka-Panas; G A Lehman; G Vasileva; Yong Shen; S Sander-Struckmeier; S Caras; D C Whitcomb
A 6-month, open-label clinical trial of pancrelipase delayed-release capsules (Creon) in patients with exocrine pancreatic insufficiency due to chronic pancreatitis or pancreatic surgery.
Alimentary pharmacology & therapeutics 2011;33(10):1152-61.
2011: Michael Ewers; Katharina Buerger; Xin Cheng; Ping He; Thomas Meindl; Hikmet F Nural; Yong Shen; Stefan J Teipel; Cathal Walsh; Zhenyu Zhong; Harald Hampel
Increased CSF-BACE1 activity associated with decreased hippocampus volume in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2011;25(2):373-81.
2010: Sang-Won Min; Seo-Hyun Cho; Yungui Zhou; Sebastian Schroeder; Vahram Haroutunian; William W Seeley; Eric J Huang; Yong Shen; Eliezer Masliah; Chandrani Mukherjee; DAVID MEYERS; Philip A Cole; Melanie Ott; Li Gan
Acetylation of tau inhibits its degradation and contributes to tauopathy.
Neuron 2010;67(6):953-66.
2010: Lin-Feng Wang; Ying-Ze Zhang; Yong Shen; Yan-Ling Su; Jia-Xin Xu; Wen-Yuan Ding; Ying-Hua Zhang
Using the T2-weighted magnetic resonance imaging signal intensity ratio and clinical manifestations to assess the prognosis of patients with cervical ossification of the posterior longitudinal ligament.
Journal of neurosurgery. Spine 2010;13(3):319-23.
2010: Peng Zhang; Ying-ze Zhang; Jun-ming Cao; Wen-yuan Ding; Yong Shen; Jia-xin Xu
Transient paraparesis after anterior decompression in a patient with ossification of the cervical posterior longitudinal ligament.
Orthopaedic surgery 2010;2(3):234-6.
2010: Harald Hampel; Yong Shen; Dominic M Walsh; Paul Aisen; Les M Shaw; Henrik Zetterberg; John Q Trojanowski; Kaj Blennow
Biological markers of amyloid beta-related mechanisms in Alzheimer's disease.
Experimental neurology 2010;223(2):334-46.
2010: Tsuyoshi Furuya; Minsu Kim; Marta Lipinski; Juying Li; Dohoon Kim; Tao Lu; Yong Shen; Lucia Rameh; Bruce Yankner; Li-Huei Tsai; Junying Yuan
Negative regulation of Vps34 by Cdk mediated phosphorylation.
Molecular cell 2010;38(4):500-11.
2010: Carrie McAllister; Jiangang Long; Adrienne Bowers; Aaron Walker; Philip Cao; Shin-Ichiro Honda; Nobuhiro Harada; Matthias Staufenbiel; Yong Shen; Rena Li
Genetic targeting aromatase in male amyloid precursor protein transgenic mice down-regulates beta-secretase (BACE1) and prevents Alzheimer-like pathology and cognitive impairment.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(21):7326-34.
2010: Jun-ming Cao; Yong Shen; Ying-ze Zhang; Wen-yuan Ding
Complications of Bryan cervical disc replacement.
Orthopaedic surgery 2010;2(2):86-93.
2010: Ying-Ze Zhang; Yong Shen; Lin-Feng Wang; Wen-Yuan Ding; Jia-Xin Xu; Jie He
Magnetic resonance T2 image signal intensity ratio and clinical manifestation predict prognosis after surgical intervention for cervical spondylotic myelopathy.
Spine 2010;35(10):E396-9.
2010: Xin Cheng; Libang Yang; Ping He; Rena Li; Yong Shen
Differential activation of tumor necrosis factor receptors distinguishes between brains from Alzheimer's disease and non-demented patients.
Journal of Alzheimer's disease : JAD 2010;19(2):621-30.
2009: Wen-yuan Ding; Zhao Guo; Bao-jun Li; Yong Shen; Wei Zhang; Ying-ze Zhang; Hong-liang Chen
Posterolateral transforaminal interbody fusion for thoracic disc herniation: a retrospective study of 38 cases.
Orthopaedic surgery 2009;1(4):280-4.
2009: Kaushik Ghosal; Daniel L Vogt; Man Liang; Yong Shen; Bruce T Lamb; Sanjay Pimplikar
Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(43):18367-72.
2009: Alan P Kozikowski; Yihua Chen; Tapadar Subhasish; Nancy E Lewin; Peter M Blumberg; Zhenyu Zhong; Melissa A D'Annibale; Weng-Long Wang; Yong Shen; Brett Langley
Searching for disease modifiers-PKC activation and HDAC inhibition - a dual drug approach to Alzheimer's disease that decreases Abeta production while blocking oxidative stress.
ChemMedChem 2009;4(7):1095-105.
2009: Ping He; Yong Shen
Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(20):6545-57.
2009: Ying-ze Zhang; Wen-yuan Ding; Yong Shen; Lin-feng Wang; Jia-xin Xu; Jie He
The effects of MRI signal intensity changes and clinical manifestations on prognosis after surgical intervention for cervical spondylotic myelopathy.
Orthopaedic surgery 2009;1(2):101-6.
2009: S R Engel; T K Creson; Y Hao; Yong Shen; Sungho Maeng; T Nekrasova; Gary Landreth; Husseini K Manji; Guang Chen
The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement.
Molecular psychiatry 2009;14(4):448-61.
2009: Weiming Xia; Ting Yang; Ganesh Shankar; Imelda M Smith; Yong Shen; Dominic M Walsh; Dennis J Selkoe
A specific enzyme-linked immunosorbent assay for measuring beta-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease.
Archives of neurology 2009;66(2):190-9.
2009: Zhenyu Zhong; Hikmet Nural; Ping He; Gina Civarella; Thomas Beach; Lucia Sue; Charles H Adler; Holly Shill; John Caviness; Weiming Xia; Yong Shen
Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients.
Molecular neurodegeneration 2009;4():30.
2009: Hikmet Nural; Ping He; Thomas Beach; Lucia Sue; Weiming Xia; Yong Shen
Dissembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients.
Molecular neurodegeneration 2009;4():23.
2009: Srinivas Reddy Chirapu; Boobalan Pachaiyappan; Hikmet F Nural; Xin Cheng; Hongbin Yuan; David C Lankin; Samer Abdul-Hay; Gregory R J Thatcher; Yong Shen; Alan P Kozikowski; Pavel A Petukhov
Molecular modeling, synthesis, and activity studies of novel biaryl and fused-ring BACE1 inhibitors.
Bioorganic & medicinal chemistry letters 2009;19(1):264-74.
2009: Harald Hampel; Yong Shen
Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) as a biological candidate marker of Alzheimer's disease.
Scandinavian journal of clinical and laboratory investigation 2009;69(1):8-12.
2008: Michael Ewers; Zhenyu Zhong; Katharina Bürger; Anders Wallin; Kaj Blennow; Stefan J Teipel; Yong Shen; Harald Hampel
Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease.
Brain : a journal of neurology 2008;131(Pt 5):1252-8.
2008: Qian Hua; Xiaolei Zhu; Pengtao Li; Huiling Tang; Dayong Cai; Ya Xu; Xu Jia; Jie Chen; Yong Shen
Refined Qing Kai Ling, traditional Chinese medicinal preparation, reduces ischemic stroke-induced infarct size and neurological deficits and increases expression of endothelial nitric oxide synthase.
Biological & pharmaceutical bulletin 2008;31(4):633-7.
2007: Ping He; Zhenyu Zhong; Kristina Lindholm; Lilian Berning; Wendy Lee; Cynthia A Lemere; Matthias Staufenbiel; Rena Li; Yong Shen
Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice.
The Journal of cell biology 2007;178(5):829-41.
2007: Giuseppina Tesco; Young Ho Koh; Eugene L Kang; Andrew N Cameron; Shinjita Das; Miguel Sena-Esteves; Mikko Hiltunen; Shao-Hua Yang; Zhenyu Zhong; Yong Shen; James W Simpkins; Rudolph E Tanzi
Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity.
Neuron 2007;54(5):721-37.
2007: Zhenyu Zhong; Michael Ewers; Stefan J Teipel; Katharina Bürger; Anders Wallin; Kaj Blennow; Ping He; Carrie McAllister; Harald Hampel; Yong Shen
Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment.
Archives of general psychiatry 2007;64(6):718-26.
2006: Yong Shen; Ping He; Zhenyu Zhong; Carrie McAllister; Kristina Lindholm
Distinct destructive signal pathways of neuronal death in Alzheimer's disease.
Trends in molecular medicine 2006;12(12):574-9.
2005: Katharina Buerger; Stefan J Teipel; Raymond Zinkowski; Trey Sunderland; Niels Andreasen; Kaj Blennow; Michael Ewers; John DeBernardis; Yong Shen; Daniel Kerkman; Yansheng Du; Harald Hampel
Increased levels of CSF phosphorylated tau in apolipoprotein E epsilon4 carriers with mild cognitive impairment.
Neuroscience letters 2005;391(1-2):48-50.
2005: Xu Yue; Melissa Lu; Techie Lancaster; Phillip Cao; Shin-Ichiro Honda; Matthias Staufenbiel; Nobuhiro Harada; Zhenyu Zhong; Yong Shen; Rena Li
Brain estrogen deficiency accelerates Abeta plaque formation in an Alzheimer's disease animal model.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(52):19198-203.
2005: Rena Li; Yong Shen
Estrogen and brain: synthesis, function and diseases.
Frontiers in bioscience : a journal and virtual library 2005;10():257-67.
2004: Elizabeth Jacobsen; Thomas Beach; Yong Shen; Rena Li; Yung Chang
Deficiency of the Mre11 DNA repair complex in Alzheimer's disease brains.
Brain research. Molecular brain research 2004;128(1):1-7.
2004: Harald Hampel; Stefan J Teipel; T Fuchsberger; Niels Andreasen; J Wiltfang; M Otto; Yong Shen; Richard Dodel; Yansheng Du; Martin R Farlow; Hans-Jürgen Möller; Kaj Blennow; Katharina Buerger
Value of CSF beta-amyloid1-42 and tau as predictors of Alzheimer's disease in patients with mild cognitive impairment.
Molecular psychiatry 2004;9(7):705-10.
2004: Rena Li; Kristina Lindholm; Li-Bang Yang; Xu Yue; Martin Citron; Riqiang Yan; Thomas Beach; Lucia I Sue; Marwan Sabbagh; Huaibin Cai; Philip C Wong; Donald L Price; Yong Shen
Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(10):3632-7.
2004: Rena Li; Libang Yang; Kristina Lindholm; Yoshihiro Konishi; Xu Yue; Harald Hampel; Dai Zhang; Yong Shen
Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(7):1760-71.
2003: Yoshihiro Konishi; Thomas Beach; Lucia I Sue; Harald Hampel; Kristina Lindholm; Yong Shen
The temporal localization of frame-shift ubiquitin-B and amyloid precursor protein, and complement proteins in the brain of non-demented control patients with increasing Alzheimer's disease pathology.
Neuroscience letters 2003;348(1):46-50.
2003: Yong Shen; Seppo Meri
Yin and Yang: complement activation and regulation in Alzheimer's disease.
Progress in neurobiology 2003;70(6):463-72.
2003: Li-Bang Yang; Kristina Lindholm; Riqiang Yan; Martin Citron; Weiming Xia; Xiao-Li Yang; Thomas Beach; Lucia I Sue; Philip C Wong; Donald L Price; Rena Li; Yong Shen
Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease.
Nature medicine 2003;9(1):3-4.
2002: Yoshihiro Konishi; Kristina Lindholm; Li-Bang Yang; Rena Li; Yong Shen
Isolation of living neurons from human elderly brains using the immunomagnetic sorting DNA-linker system.
The American journal of pathology 2002;161(5):1567-76.
2002: Huang Chun Tseng; Ying Zhou; Yong Shen; Li-Huei Tsai
A survey of Cdk5 activator p35 and p25 levels in Alzheimer's disease brains.
FEBS letters 2002;523(1-3):58-62.
2002: Libang Yang; Kristina Lindholm; Yoshihiro Konishi; Rena Li; Yong Shen
Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(8):3025-32.
2001: Lih-Fen Lue; Russell E Rydel; E F Brigham; L B Yang; Harald Hampel; G M Murphy; L Brachova; Shi Du Yan; Douglas G. Walker; Yong Shen; Joseph Rogers
Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro.
Glia 2001;35(1):72-9.
2001: Ikuo Tooyama; H Sato; Osamu Yasuhara; H Kimura; Yoshihiro Konishi; Yong Shen; Douglas G. Walker; Thomas Beach; Lucia I Sue; Joseph Rogers
Correlation of the expression level of C1q mRNA and the number of C1q-positive plaques in the Alzheimer Disease temporal cortex. analysis of C1q mrna and its protein using adjacent or nearby sections.
Dementia and geriatric cognitive disorders 2001;12(4):237-42.
2001: Yong Shen; Lih-Fen Lue; L Yang; Alex Roher; Y Kuo; R Strohmeyer; W J Goux; Virginia M-Y Lee; Gail Johnson; S D Webster; N R Cooper; Bonnie M Bradt; Joseph Rogers
Complement activation by neurofibrillary tangles in Alzheimer's disease.
Neuroscience letters 2001;305(3):165-8.
2000: L B Yang; Rena Li; S Meri; Joseph Rogers; Yong Shen
Deficiency of complement defense protein CD59 may contribute to neurodegeneration in Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(20):7505-9.
2000: Rena Li; Yong Shen; L B Yang; Lih-Fen Lue; Caleb E Finch; Joseph Rogers
Estrogen enhances uptake of amyloid beta-protein by microglia derived from the human cortex.
Journal of neurochemistry 2000;75(4):1447-54.
2000: Ron Strohmeyer; Yong Shen; Joseph Rogers
Detection of complement alternative pathway mRNA and proteins in the Alzheimer's disease brain.
Brain research. Molecular brain research 2000;81(1-2):7-18.
2000: Haruhiko Akiyama; Steven W Barger; S Barnum; B Bradt; J Bauer; Gregory M. Cole; N R Cooper; Piet Eikelenboom; M Emmerling; B L Fiebich; Caleb E Finch; S Frautschy; W S Griffin; Harald Hampel; M Hull; Gary Landreth; Lih-Fen Lue; R Mrak; I R Mackenzie; Patrick L McGeer; M K O'Banion; Joel S. Pachter; Giulio Maria Pasinetti; C Plata-Salaman; Joseph Rogers; R Rydel; Yong Shen; W Streit; R Strohmeyer; I Tooyoma; F L Van Muiswinkel; R Veerhuis; Douglas G. Walker; S Webster; B Wegrzyniak; Gary L Wenk; Tony Wyss-Coray
Inflammation and Alzheimer's disease.
Neurobiology of aging 2000;21(3):383-421.
2000: Joseph Rogers; Yong Shen
A perspective on inflammation in Alzheimer's disease.
Annals of the New York Academy of Sciences 2000;924():132-5.
1999: Lih-Fen Lue; Yu-Min Kuo; Alex Roher; L Brachova; Yong Shen; Lucia I Sue; Thomas Beach; J H Kurth; Russell E Rydel; Joseph Rogers
Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease.
The American journal of pathology 1999;155(3):853-62.
1998: Yong Shen; Rena Li
Expressing mRNAs for presenilin-1 and amyloid precursor protein (APP-695) from same neuronal populations in rat hippocampus.
Brain research bulletin 1998;46(3):233-6.
1997: Yong Shen; Rena Li; Edith G McGeer; Patrick L McGeer
Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain.
Brain research 1997;769(2):391-5.
1995: Yong Shen; J A Halperin; C M Lee
Complement-mediated neurotoxicity is regulated by homologous restriction.
Brain research 1995;671(2):282-92.
1994: Yong Shen; S M Specht; I De Saint Ghislain; Rena Li
The hippocampus: a biological model for studying learning and memory.
Progress in neurobiology 1994;44(5):485-96.
1992: Yong Shen
[A case-control study of risk factors on Alzheimer's disease. Multicenter collaborative study in China].
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry 1992;25(5):284-7, 317.
1991: Rena Li; L L Wing; Yong Shen; RJ Wyatt; D G Kirch; D M Chuang
Chronic haloperidol treatment attenuates receptor-mediated phosphoinositide turnover in rat brain slices.
Neuroscience letters 1991;129(1):81-5.