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Shalom (Shlomi) Madar

Research Profile

Chemicals & Drugs

Physiology

Disorders

Anatomy

Genes & Molecular Sequences

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Publications

TOP 3
R Brosh; E Dekel; Naomi Goldfinger; Shalom (Shlomi) Madar; A Molchadsky; N Rivlin; Y Assia-Alroy; C Bornstein; Rachel Sarig; Y Shetzer; Varda Rotter
p53 counteracts reprogramming by inhibiting mesenchymal-to-epithelial transition.
Shalom (Shlomi) Madar; Hilla Solomon; Yan Stein; Perry Tal; Elya Dekel; Gilgi Friedlander; Naomi Goldfinger; Ido Goldstein; Einav Harel; Iris Kamer; Ira Kogan-Sakin; Varda Rotter
Mutant p53 Attenuates the Anti-Tumorigenic Activity of Fibroblasts-Secreted Interferon Beta.
Ido Goldstein; Shalom (Shlomi) Madar; Noa Rivlin; Osnat Ezra; Naomi Goldfinger; Or-yam Shoshana; Varda Rotter
Chemotherapeutic agents induce the expression and activity of their clearing enzyme CYP3A4 by activating p53.

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All Publications

2013: R Brosh; E Dekel; Naomi Goldfinger; Shalom (Shlomi) Madar; A Molchadsky; N Rivlin; Y Assia-Alroy; C Bornstein; Rachel Sarig; Y Shetzer; Varda Rotter
p53 counteracts reprogramming by inhibiting mesenchymal-to-epithelial transition.
Cell death and differentiation 2013;20(2):312-20.
2013: Shalom (Shlomi) Madar; Hilla Solomon; Yan Stein; Perry Tal; Elya Dekel; Gilgi Friedlander; Naomi Goldfinger; Ido Goldstein; Einav Harel; Iris Kamer; Ira Kogan-Sakin; Varda Rotter
Mutant p53 Attenuates the Anti-Tumorigenic Activity of Fibroblasts-Secreted Interferon Beta.
PloS one 2013;8(4):e61353.
2013: Ido Goldstein; Shalom (Shlomi) Madar; Noa Rivlin; Osnat Ezra; Naomi Goldfinger; Or-yam Shoshana; Varda Rotter
Chemotherapeutic agents induce the expression and activity of their clearing enzyme CYP3A4 by activating p53.
Carcinogenesis 2013;34(1):190-8.
2012: Ofer Shoshani; Luba Trakhtenbrot; Sivan Kagan; Dena Leshkowitz; Shalom (Shlomi) Madar; Hassan Massalha; Orly Ravid; Gideon Rechavi; Nir Shani; Dov Zipori
Polyploidization of murine mesenchymal cells is associated with suppression of the long noncoding RNA H19 and reduced tumorigenicity.
Cancer research 2012;72(24):6403-13.
2012: Eyal Kalo; Ira Kogan-Sakin; Shalom (Shlomi) Madar; Elad Bar-Nathan; Yosef Buganim; Elya Dekel; Naomi Goldfinger; Ido Goldstein; Moshe Shay; Yoav Shetzer; Hilla Solomon; Perry Stambolsky; Varda Rotter
Mutant p53R273H attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species.
Journal of cell science 2012;125(Pt 22):5578-86.
2012: Hilla Solomon; Yael Assia; Tsevi Beatus; Ran Brosh; Yosef Buganim; Naomi Goldfinger; Ido Goldstein; Eyal Kalo; Ira Kogan-Sakin; Shalom (Shlomi) Madar; Leslie Pomeraniec; Varda Rotter
Various p53 mutant proteins differently regulate the Ras circuit to induce a cancer-related gene signature.
Journal of cell science 2012;125(Pt 13):3144-52.
2012: Ido Goldstein; Shalom (Shlomi) Madar; Varda Rotter
Cancer research, a field on the verge of a paradigm shift?
Trends in molecular medicine 2012;18(6):299-303.
2012: Ido Goldstein; Shalom (Shlomi) Madar; Alina Molchadsky; Noa Rivlin; Osnat Ezra; Naomi Goldfinger; Varda Rotter
p53, a novel regulator of lipid metabolism pathways.
Journal of hepatology 2012;56(3):656-62.
2011: Shalom (Shlomi) Madar; Ortal Neeman; Ido Goldstein; Varda Rotter
Beyond tumor suppression: p53 controls blastocyst implantation.
Cell cycle (Georgetown, Tex.) 2011;10(24):4203.
2011: Hilla Solomon; Shalom (Shlomi) Madar; Varda Rotter
Mutant p53 gain of function is interwoven into the hallmarks of cancer.
The Journal of pathology 2011;225(4):475-8.
2011: Yosef Buganim; Naomi Goldfinger; Ido Goldstein; Ora Haimov; Einav Harel; Eyal Kalo; Shalom (Shlomi) Madar; Sylvie Polak-Charcon; Leslie Pomeraniec; Yoach Rais; Camila Avivi; Iris Barshack; Ran Brosh; Hilla Solomon; Varda Rotter
Transcriptional activity of ATF3 in the stromal compartment of tumors promotes cancer progression.
Carcinogenesis 2011;32(12):1749-57.
2011: Shalom (Shlomi) Madar; Hilla Solomon; Varda Rotter
Same stem cells but different: Isogenic embryonic stem cells harboring different p53 mutants.
Cell cycle (Georgetown, Tex.) 2011;10(14):2248-9.
2011: Chamutal Bornstein; Ran Brosh; Alina Molchadsky; Shalom (Shlomi) Madar; Ira Kogan-Sakin; Ido Goldstein; Deepavali Chakravarti; Elsa R Flores; Naomi Goldfinger; Rachel Sarig; Varda Rotter
SPATA18, a spermatogenesis-associated gene, is a novel transcriptional target of p53 and p63.
Molecular and cellular biology 2011;31(8):1679-89.
2011: Shalom (Shlomi) Madar; Perry Stambolsky; Varda Rotter
Unleash the wild type: restoration of p53 suppressive activity in skin cancer.
Cell cycle (Georgetown, Tex.) 2011;10(5):736-7.
2011: I Kogan-Sakin; Yuval Tabach; Yosef Buganim; A Molchadsky; H Solomon; Shalom (Shlomi) Madar; I Kamer; Perry Stambolsky; A Shelly; Naomi Goldfinger; S Valsesia-Wittmann; A Puisieux; A Zundelevich; E N Gal-Yam; C Avivi; Iris Barshack; Mariana Brait; David Sidransky; E Domany; Varda Rotter
Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.
Cell death and differentiation 2011;18(2):271-81.
2011: Orit Leshem; Ron Loewenthal; Shalom (Shlomi) Madar; Varda Rotter; Shmuel Ben-Sasson; Ran Brosh; Yehudit Cohen; Marcelo Ehrlich; Ephraim Gazit; Naomi Goldfinger; Ido Goldstein; Jasmine Jacob-Hirsch; Iris Kamer; Ira Kogan-Sakin; Raanan Berger
TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model.
PloS one 2011;6(7):e21650.
2010: Ran Brosh; Rachel Sarig; Elad Bar Natan; Alina Molchadsky; Shalom (Shlomi) Madar; Chamutal Bornstein; Yosef Buganim; Tirosh Shapira; Naomi Goldfinger; Ralf Paus; Varda Rotter
p53-dependent transcriptional regulation of EDA2R and its involvement in chemotherapy-induced hair loss.
FEBS letters 2010;584(11):2473-7.
2010: Yosef Buganim; Hilla Solomon; Yoach Rais; Daria Kistner; Ido Nachmany; Mariana Brait; Shalom (Shlomi) Madar; Ido Goldstein; Eyal Kalo; Nitzan Adam; Maya Gordin; Noa Rivlin; Ira Kogan; Ran Brosh; Galit Sefadia-Elad; Naomi Goldfinger; David Sidransky; Yoel Kloog; Varda Rotter
p53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways.
Cancer research 2010;70(6):2274-84.
2010: Yosef Buganim; Ido Goldstein; Doron Lipson; Michael Milyavsky; Sylvie Polak-Charcon; Corine Mardoukh; Hilla Solomon; Eyal Kalo; Shalom (Shlomi) Madar; Ran Brosh; Marina Perelman; Roy Navon; Naomi Goldfinger; Iris Barshack; Zohar Yakhini; Varda Rotter
A novel translocation breakpoint within the BPTF gene is associated with a pre-malignant phenotype.
PloS one 2010;5(3):e9657.
2009: Shalom (Shlomi) Madar; Ido Goldstein; Varda Rotter
Did experimental biology die? Lessons from 30 years of p53 research.
Cancer research 2009;69(16):6378-80.
2009: Nicole Paland; Iris Kamer; Ira Kogan-Sakin; Shalom (Shlomi) Madar; Naomi Goldfinger; Varda Rotter
Differential influence of normal and cancer-associated fibroblasts on the growth of human epithelial cells in an in vitro cocultivation model of prostate cancer.
Molecular cancer research : MCR 2009;7(8):1212-23.
2009: Ira Kogan-Sakin; Merav Cohen; Nicole Paland; Shalom (Shlomi) Madar; Hilla Solomon; Alina Molchadsky; Ran Brosh; Yosef Buganim; Naomi Goldfinger; Helmut Klocker; Jack A Schalken; Varda Rotter
Prostate stromal cells produce CXCL-1, CXCL-2, CXCL-3 and IL-8 in response to epithelia-secreted IL-1.
Carcinogenesis 2009;30(4):698-705.
2009: Shalom (Shlomi) Madar; Ran Brosh; Yosef Buganim; Osnat Ezra; Ido Goldstein; Hilla Solomon; Ira Kogan; Naomi Goldfinger; Helmut Klocker; Varda Rotter
Modulated expression of WFDC1 during carcinogenesis and cellular senescence.
Carcinogenesis 2009;30(1):20-7.
2008: Ran Brosh; Reut Shalgi; Atar Liran; Gilad Landan; Katya Korotayev; Giang Huong Nguyen; Espen Enerly; Hilde Johnsen; Yosef Buganim; Hilla Solomon; Ido Goldstein; Shalom (Shlomi) Madar; Naomi Goldfinger; Anne-Lise Børresen-Dale; Doron Ginsberg; Curtis C Harris; Yitzhak Pilpel; Moshe Oren; Varda Rotter
p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation.
Molecular systems biology 2008;4():229.
2007: Michael Milyavsky; Igor Shats; Alina Cholostoy; Ran Brosh; Yosef Buganim; Lilach Weisz; Ira Kogan; Merav Cohen; Maria Shatz; Shalom (Shlomi) Madar; Eyal Kalo; Naomi Goldfinger; Jun Yuan; Shulamit Ron; Karen MacKenzie; Amir Eden; Varda Rotter
Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect.
Cancer cell 2007;11(2):133-46.