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David Wallach

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
18
Engelmann, Hartmut
17
Holtmann, Helmut
15
Varfolomeev, Eugene
13
Kovalenko, Andrew
13
Boldin, Mark
8
Malinin, NL
8
Pastan, Ira
7
taebong, kang
6
Kovalenko, Andrew
6
Revel, Michel
5
Resch, Klaus
5
Novick, Daniela
4
Ramakrishnan, Parameswaran
4
Schuchmann, Marcus
4
Winzen, Reinhard

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Publications

TOP 3
Kovalenko Andrew; Kim Jin-Chul; Kang Tae-Bong; Rajput Akhil; Bogdanov Konstantin; Dittrich-Breiholz Oliver; Kracht Michael; Brenner Ori; Wallach David
Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease.
Wallach David; Kovalenko Andrew
12th international TNF conference: the good, the bad and the scientists.
Wallach David; Kovalenko Andrew
Self-termination of the terminator.

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All Publications

2009: Kovalenko Andrew; Kim Jin-Chul; Kang Tae-Bong; Rajput Akhil; Bogdanov Konstantin; Dittrich-Breiholz Oliver; Kracht Michael; Brenner Ori; Wallach David
Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease.
The Journal of experimental medicine 2009;206(10):2161-77.
2009: Wallach David; Kovalenko Andrew
12th international TNF conference: the good, the bad and the scientists.
Cytokine & growth factor reviews 2009;20(4):259-69.
2008: Wallach David; Kovalenko Andrew
Self-termination of the terminator.
Nature immunology 2008;9(12):1325-7.
2008: Wallach D; Kang T-B; Kovalenko A
The extrinsic cell death pathway and the élan mortel.
Cell death and differentiation 2008;15(10):1533-41.
2008: Krelin Y; Zhang L; Kang T-B; Appel E; Kovalenko A; Wallach D
Caspase-8 deficiency facilitates cellular transformation in vitro.
Cell death and differentiation 2008;15(9):1350-5.
2008: Kang Tae-Bong; Oh Gi-Su; Scandella Elke; Bolinger Beatrice; Ludewig Burkhard; Kovalenko Andrew; Wallach David
Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(4):2522-32.
2008: Ben Moshe Tehila; Kang Tae-Bong; Kovalenko Andrew; Barash Hila; Abramovitch Rinat; Galun Eithan; Wallach David
Cell-autonomous and non-cell-autonomous functions of caspase-8.
Cytokine & growth factor reviews 2008;19(3-4):209-17.
2007: Hövelmeyer Nadine; Wunderlich F Thomas; Massoumi Ramin; Jakobsen Charlotte G; Song Jian; Wörns Marcus A; Merkwirth Carsten; Kovalenko Andrew; Aumailley Monique; Strand Dennis; Brüning Jens C; Galle Peter R; Wallach David; Fässler Reinhard; Waisman Ari
Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD.
The Journal of experimental medicine 2007;204(11):2615-27.
2007: Peter Marcus E; Budd Ralph C; Desbarats Julie; Hedrick Stephen M; Hueber Anne-Odile; Newell M Karen; Owen Laurie B; Pope Richard M; Tschopp Juerg; Wajant Harald; Wallach David; Wiltrout Robert H; Zörnig Martin; Lynch David H
The CD95 receptor: apoptosis revisited.
Cell 2007;129(3):447-50.
2007: Ben Moshe Tehila; Barash Hila; Kang Tae-Bong; Kim Jin-Chul; Kovalenko Andrew; Gross Eitan; Schuchmann Marcus; Abramovitch Rinat; Galun Eithan; Wallach David
Role of caspase-8 in hepatocyte response to infection and injury in mice.
Hepatology (Baltimore, Md.) 2007;45(4):1014-24.
2006: Gyrd-Hansen Mads; Farkas Thomas; Fehrenbacher Nicole; Bastholm Lone; Høyer-Hansen Maria; Elling Folmer; Wallach David; Flavell Richard; Kroemer Guido; Nylandsted Jesper; Jäättelä Marja
Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9.
Molecular and cellular biology 2006;26(21):7880-91.
2006: Kovalenko Andrew; Wallach David
If the prophet does not come to the mountain: dynamics of signaling complexes in NF-kappaB activation.
Molecular cell 2006;22(4):433-6.
2006: Citri Ami; Harari Daniel; Shohat Galit; Ramakrishnan Parameswaran; Gan Judith; Lavi Sara; Eisenstein Miriam; Kimchi Adi; Wallach David; Pietrokovski Shmuel; Yarden Yosef
Hsp90 recognizes a common surface on client kinases.
The Journal of biological chemistry 2006;281(20):14361-9.
2006: Helfer Brooke; Boswell Bernard C; Finlay Darren; Cipres Angel; Vuori Kristiina; Bong Kang Tae; Wallach David; Dorfleutner Andrea; Lahti Jill M; Flynn Daniel C; Frisch Steven M
Caspase-8 promotes cell motility and calpain activity under nonapoptotic conditions.
Cancer research 2006;66(8):4273-8.
2006: Sánchez-Valdepeñas Carmen; Martín Angel G; Ramakrishnan Parameswaran; Wallach David; Fresno Manuel
NF-kappaB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):4666-74.
2005: Schuchmann Marcus; Ruckert Felix; Garcia-Lazaro Jose F; Karg Andrea; Burg Jurgen; Knorr Natalia; Siebler Jurgen; Varfolomeev Eugene E; Wallach David; Schreiber Wolfgang; Lohse Ansgar W; Galle Peter R
MORT1/FADD is involved in liver regeneration.
World journal of gastroenterology : WJG 2005;11(46):7248-53.
2005: Wallach David
Probing cell death by chemical screening.
Nature chemical biology 2005;1(2):68-9.
2004: Ramakrishnan Parameswaran; Wang Wangxia; Wallach David
Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase.
Immunity 2004;21(4):477-89.
2004: Kang Tae-Bong; Ben-Moshe Tehila; Varfolomeev Eugene E; Pewzner-Jung Yael; Yogev Nir; Jurewicz Anna; Waisman Ari; Brenner Ori; Haffner Rebecca; Gustafsson Erika; Ramakrishnan Parameswaran; Lapidot Tsvee; Wallach David
Caspase-8 serves both apoptotic and nonapoptotic roles.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):2976-84.
2004: Xanthoulea Sofia; Pasparakis Manolis; Kousteni Stavroula; Brakebusch Cord; Wallach David; Bauer Jan; Lassmann Hans; Kollias George
Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases.
The Journal of experimental medicine 2004;200(3):367-76.
2004: Greenberger Shoshana; Shaish Aviv; Varda-Bloom Nira; Levanon Keren; Breitbart Eyal; Goldberg Iris; Barshack Iris; Hodish Israel; Yaacov Niva; Bangio Livnat; Goncharov Tanya; Wallach David; Harats Dror
Transcription-controlled gene therapy against tumor angiogenesis.
The Journal of clinical investigation 2004;113(7):1017-24.
2004: Engelmann Hartmut; Aderka Dani; Wallach David
Purification of TNF binding proteins.
Methods in molecular medicine 2004;98():23-32.
2003: Zalcenstein Amir; Stambolsky Perry; Weisz Lilach; Müller Martina; Wallach David; Goncharov Tanya M; Krammer Peter H; Rotter Varda; Oren Moshe
Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants.
Oncogene 2003;22(36):5667-76.
2003: Kovalenko Andrew; Chable-Bessia Christine; Cantarella Giuseppina; Israël Alain; Wallach David; Courtois Gilles
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination.
Nature 2003;424(6950):801-5.
2003: Schuchmann Marcus; Varfolomeev Eugene E; Hermann Frank; Rueckert Felix; Strand Dennis; Koehler Heinz; Strand Susanne; Lohse Ansgar W; Wallach David; Galle Peter R
Dominant negative MORT1/FADD rescues mice from CD95 and TNF-induced liver failure.
Hepatology (Baltimore, Md.) 2003;37(1):129-35.
2002: Heussler Volker T; Rottenberg Sven; Schwab Rebekka; Küenzi Peter; Fernandez Paula C; McKellar Susan; Shiels Brian; Chen Zhijian J; Orth Kim; Wallach David; Dobbelaere Dirk A E
Hijacking of host cell IKK signalosomes by the transforming parasite Theileria.
Science (New York, N.Y.) 2002;298(5595):1033-6.
2002: Wallach David
Up the down staircase.
Nature immunology 2002;3(9):802-3.
2002: Wallach David; Arumugam Thangavelu U; Boldin Mark P; Cantarella Giuseppina; Ganesh Koluman A; Goltsev Yuri; Goncharov Tanya M; Kovalenko Andrew V; Rajput Akhil; Varfolomeev Eugene E; Zhang Si Qing
How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-kappaB activation by members of the TNF/NGF receptor family.
Arthritis research 2002;4 Suppl 3():S189-96.
2000: Zhang S Q; Kovalenko A; Cantarella G; Wallach D
Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation.
Immunity 2000;12(3):301-11.
1999: Holtmann H; Winzen R; Holland P; Eickemeier S; Hoffmann E; Wallach D; Malinin N L; Cooper J A; Resch K; Kracht M
Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways.
Molecular and cellular biology 1999;19(10):6742-53.
1999: Watts A D; Hunt N H; Wanigasekara Y; Bloomfield G; Wallach D; Roufogalis B D; Chaudhri G
A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'.
The EMBO journal 1999;18(8):2119-26.
1999: Li Y; Kang J; Friedman J; Tarassishin L; Ye J; Kovalenko A; Wallach D; Horwitz M S
Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(3):1042-7.
1999: Wallach D; Varfolomeev E E; Malinin N L; Goltsev Y V; Kovalenko A V; Boldin M P
Tumor necrosis factor receptor and Fas signaling mechanisms.
Annual review of immunology 1999;17():331-67.
1998: Varfolomeev E E; Schuchmann M; Luria V; Chiannilkulchai N; Beckmann J S; Mett I L; Rebrikov D; Brodianski V M; Kemper O C; Kollet O; Lapidot T; Soffer D; Sobe T; Avraham K B; Goncharov T; Holtmann H; Lonai P; Wallach D
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.
Immunity 1998;9(2):267-76.
1998: Sylla B S; Hung S C; Davidson D M; Hatzivassiliou E; Malinin N L; Wallach D; Gilmore T D; Kieff E; Mosialos G
Epstein-Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-kappaB through a pathway that includes the NF-kappaB-inducing kinase and the IkappaB kinases IKKalpha and IKKbeta.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(17):10106-11.
1998: Wallach D; Kovalenko A V; Varfolomeev E E; Boldin M P
Death-inducing functions of ligands of the tumor necrosis factor family: a Sanhedrin verdict.
Current opinion in immunology 1998;10(3):279-88.
1998: Akiba H; Nakano H; Nishinaka S; Shindo M; Kobata T; Atsuta M; Morimoto C; Ware C F; Malinin N L; Wallach D; Yagita H; Okumura K
CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase.
The Journal of biological chemistry 1998;273(21):13353-8.
1998: Wallach D; Boldin M P; Kovalenko A V; Malinin N L; Mett I L; Camonis J H
The yeast two-hybrid screening technique and its use in the study of protein-protein interactions in apoptosis.
Current opinion in immunology 1998;10(2):131-6.
1998: Carpentier I; Declercq W; Malinin N L; Wallach D; Fiers W; Beyaert R
TRAF2 plays a dual role in NF-kappaB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IkappaB kinase pathways.
FEBS letters 1998;425(2):195-8.
1998: Aderka D; Sorkine P; Abu-Abid S; Lev D; Setton A; Cope A P; Wallach D; Klausner J
Shedding kinetics of soluble tumor necrosis factor (TNF) receptors after systemic TNF leaking during isolated limb perfusion. Relevance to the pathophysiology of septic shock.
The Journal of clinical investigation 1998;101(3):650-9.
1997: Goltsev Y V; Kovalenko A V; Arnold E; Varfolomeev E E; Brodianskii V M; Wallach D
CASH, a novel caspase homologue with death effector domains.
The Journal of biological chemistry 1997;272(32):19641-4.
1997: Wallach D
Apoptosis. Placing death under control.
Nature 1997;388(6638):123, 125-6.
1997: Wallach D; Boldin M; Varfolomeev E; Beyaert R; Vandenabeele P; Fiers W
Cell death induction by receptors of the TNF family: towards a molecular understanding.
FEBS letters 1997;410(1):96-106.
1997: Wallach D
Cell death induction by TNF: a matter of self control.
Trends in biochemical sciences 1997;22(4):107-9.
1997: Malinin N L; Boldin M P; Kovalenko A V; Wallach D
MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1.
Nature 1997;385(6616):540-4.
1996: Wallach D
A decade of accumulated knowledge and emerging answers. The 6th international congress on TNF Rhodes, Greece. May 1996.
European cytokine network 1996;7(4):713-24.
1996: Wallach D
Suicide by order: some open questions about the cell-killing activities of the TNF ligand and receptor families.
Cytokine & growth factor reviews 1996;7(3):211-21.
1996: Wallach D; Boldin M; Goncharov T; Goltsev Y; Mett I; Malinin N; Adar R; Kovalenko A; Varfolomeev E
Exploring cell death mechanisms by analyzing signaling cascades of the TNF/NGF receptor family.
Behring Institute Mitteilungen 1996;(97):144-55.
1996: Kupferminc M J; Peaceman A M; Aderka D; Wallach D; Socol M L
Soluble tumor necrosis factor receptors and interleukin-6 levels in patients with severe preeclampsia.
Obstetrics and gynecology 1996;88(3):420-7.
1996: Eliaz R; Wallach D; Kost J
Long-term protection against the effects of tumour necrosis factor by controlled delivery of the soluble p55 TNF receptor.
Cytokine 1996;8(6):482-7.
1996: Boldin M P; Goncharov T M; Goltsev Y V; Wallach D
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death.
Cell 1996;85(6):803-15.
1996: Shohami E; Bass R; Wallach D; Yamin A; Gallily R
Inhibition of tumor necrosis factor alpha (TNFalpha) activity in rat brain is associated with cerebroprotection after closed head injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(3):378-84.
1996: Tur-Kaspa I; Maor Y; Weissenberg R; Madgar I; Aderka D; Dor J; Mashiach S; Wallach D
High levels of soluble p55-TNF receptors in seminal and prostatic fluids of normal and infertile men.
The Journal of urology 1996;155(4):1436-8.
1996: Varfolomeev E E; Boldin M P; Goncharov T M; Wallach D
A potential mechanism of "cross-talk" between the p55 tumor necrosis factor receptor and Fas/APO1: proteins binding to the death domains of the two receptors also bind to each other.
The Journal of experimental medicine 1996;183(3):1271-5.
1995: Kalinkovich A; Geleziunas R; Kemper O; Belenki D; Wallach D; Wainberg M A; Bentwich Z
Increased soluble tumor necrosis factor receptor expression and release by human immunodeficiency virus type 1 infection.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1995;15(9):749-57.
1995: Kupferminc M J; Peaceman A M; Aderka D; Wallach D; Peyser M R; Lessing J B; Socol M L
Soluble tumor necrosis factor receptors in maternal plasma and second-trimester amniotic fluid.
American journal of obstetrics and gynecology 1995;173(3 Pt 1):900-5.
1995: Feinstein E; Kimchi A; Wallach D; Boldin M; Varfolomeev E
The death domain: a module shared by proteins with diverse cellular functions.
Trends in biochemical sciences 1995;20(9):342-4.
1995: Schuchmann M; Hess S; Bufler P; Brakebusch C; Wallach D; Porter A; Riethmüller G; Engelmann H
Functional discrepancies between tumor necrosis factor and lymphotoxin alpha explained by trimer stability and distinct receptor interactions.
European journal of immunology 1995;25(8):2183-9.
1995: Opsjøn S L; Novick D; Wathen N C; Cope A P; Wallach D; Aderka D
Soluble tumor necrosis factor receptors and soluble interleukin-6 receptor in fetal and maternal sera, coelomic and amniotic fluids in normal and pre-eclamptic pregnancies.
Journal of reproductive immunology 1995;29(2):119-34.
1995: Porat R; Paddock H N; Schwaitzberg S D; Connolly R J; Wilkens T; Dasch J R; Gascon M P; Hutchison J S; Ythier A; Wallach D
Glycosylated recombinant human tumor necrosis factor binding protein-1 reduces mortality, shock, and production of tumor necrosis factor in rabbit Escherichia coli sepsis.
Critical care medicine 1995;23(6):1080-9.
1995: Boldin M P; Mett I L; Wallach D
A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its 'death domain'.
FEBS letters 1995;367(1):39-44.
1995: Boldin M P; Varfolomeev E E; Pancer Z; Mett I L; Camonis J H; Wallach D
A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain.
The Journal of biological chemistry 1995;270(14):7795-8.
1995: Cope A P; Aderka D; Wallach D; Kahan M; Chu N R; Brennan F M; Feldmann M
Soluble TNF receptor production by activated T lymphocytes: differential effects of acute and chronic exposure to TNF.
Immunology 1995;84(1):21-30.
1995: Boldin M P; Mett I L; Varfolomeev E E; Chumakov I; Shemer-Avni Y; Camonis J H; Wallach D
Self-association of the "death domains" of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects.
The Journal of biological chemistry 1995;270(1):387-91.
1995: Pócsik E; Duda E; Wallach D
Phosphorylation of the 26 kDa TNF precursor in monocytic cells and in transfected HeLa cells.
Journal of inflammation 1995;45(3):152-60.
1994: Kuhnert P; Kemper O; Wallach D
Cloning, sequencing and partial functional characterization of the 5' region of the human p75 tumor necrosis factor receptor-encoding gene (TNF-R).
Gene 1994;150(2):381-6.
1994: Brakebusch C; Varfolomeev E E; Batkin M; Wallach D
Structural requirements for inducible shedding of the p55 tumor necrosis factor receptor.
The Journal of biological chemistry 1994;269(51):32488-96.
1994: Bigda J; Beletsky I; Brakebusch C; Varfolomeev Y; Engelmann H; Bigda J; Holtmann H; Wallach D
Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity.
The Journal of experimental medicine 1994;180(2):445-60.
1994: Boka G; Anglade P; Wallach D; Javoy-Agid F; Agid Y; Hirsch E C
Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease.
Neuroscience letters 1994;172(1-2):151-4.
1994: Ettehadi P; Greaves M W; Wallach D; Aderka D; Camp R D
Elevated tumour necrosis factor-alpha (TNF-alpha) biological activity in psoriatic skin lesions.
Clinical and experimental immunology 1994;96(1):146-51.
1994: Alon R; Cahalon L; Hershkoviz R; Elbaz D; Reizis B; Wallach D; Akiyama S K; Yamada K M; Lider O
TNF-alpha binds to the N-terminal domain of fibronectin and augments the beta 1-integrin-mediated adhesion of CD4+ T lymphocytes to the glycoprotein.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(3):1304-13.
1993: Kemper O; Wallach D
Cloning and partial characterization of the promoter for the human p55 tumor necrosis factor (TNF) receptor.
Gene 1993;134(2):209-16.
1993: Molyneux M E; Engelmann H; Taylor T E; Wirima J J; Aderka D; Wallach D; Grau G E
Circulating plasma receptors for tumour necrosis factor in Malawian children with severe falciparum malaria.
Cytokine 1993;5(6):604-9.
1993: Kalinkovich A; Livshits G; Engelmann H; Harpaz N; Burstein R; Kaminsky M; Wallach D; Bentwich Z
Soluble tumour necrosis factor receptors (sTNF-R) and HIV infection: correlation to CD8+ lymphocytes.
Clinical and experimental immunology 1993;93(3):350-5.
1993: Ythier A; Gascon M P; Juillard P; Vesin C; Wallach D; Grau G E
Protective effect of natural TNF-binding protein on human TNF-induced toxicity in mice.
Cytokine 1993;5(5):459-62.
1993: Winzen R; Wallach D; Kemper O; Resch K; Holtmann H
Selective up-regulation of the 75-kDa tumor necrosis factor (TNF) receptor and its mRNA by TNF and IL-1.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(10):4346-53.
1993: Cope A P; Gibbons D L; Aderka D; Foxwell B M; Wallach D; Maini R N; Feldmann M; Brennan F M
Differential regulation of tumour necrosis factor receptors (TNF-R) by IL-4; upregulation of P55 and P75 TNF-R on synovial joint mononuclear cells.
Cytokine 1993;5(3):205-12.
1993: Aderka D; Maor Y; Novick D; Engelmann H; Kahn Y; Levo Y; Wallach D; Revel M
Interleukin-6 inhibits the proliferation of B-chronic lymphocytic leukemia cells that is induced by tumor necrosis factor-alpha or -beta.
Blood 1993;81(8):2076-84.
1993: Belldegrun A; Pierce W; Sayah D; deKernion J; Wallach D; Aderka D; Figlin R A
Soluble tumor necrosis factor receptor expression in patients with metastatic renal cell carcinoma treated with interleukin-2-based immunotherapy.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;13(3):175-80.
1993: Noronha I L; Weis H; Hartley B; Wallach D; Cameron J S; Waldherr R
Expression of cytokines, growth factors, and their receptors in renal allograft biopsies.
Transplantation proceedings 1993;25(1 Pt 2):917-8.
1993: Hershkoviz R; Gilat D; Miron S; Mekori Y A; Aderka D; Wallach D; Vlodavsky I; Cohen I R; Lider O
Extracellular matrix induces tumour necrosis factor-alpha secretion by an interaction between resting rat CD4+ T cells and macrophages.
Immunology 1993;78(1):50-7.
1993: Miltenburg A M; Aderka D; van Laar J M; Wallach D; Breedveld F C
Levels of soluble receptors for tumor necrosis factor type I and type II in paired synovial fluids of arthritis patients.
Rheumatology international 1993;13(3):117-9.
1992: Miles D W; Aderka D; Engelmann H; Wallach D; Balkwill F R
Induction of soluble tumour necrosis factor receptors during treatment with interleukin-2.
British journal of cancer 1992;66(6):1195-9.
1992: Cope A P; Aderka D; Doherty M; Engelmann H; Gibbons D; Jones A C; Brennan F M; Maini R N; Wallach D; Feldmann M
Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases.
Arthritis and rheumatism 1992;35(10):1160-9.
1992: Kalinkovich A; Engelmann H; Harpaz N; Burstein R; Barak V; Kalickman I; Wallach D; Bentwich Z
Elevated serum levels of soluble tumour necrosis factor receptors (sTNF-R) in patients with HIV infection.
Clinical and experimental immunology 1992;89(3):351-5.
1992: Gascon M P; Porchet H C; Le Cotonnec J Y; Ythier A; Wallach D; Piguet P F; Grau G E
Pharmacokinetics and tissue distribution of human urinary tumor necrosis factor binding protein in mice.
Drug metabolism and disposition: the biological fate of chemicals 1992;20(4):592-5.
1992: Aderka D; Engelmann H; Shemer-Avni Y; Hornik V; Galil A; Sarov B; Wallach D
Variation in serum levels of the soluble TNF receptors among healthy individuals.
Lymphokine and cytokine research 1992;11(3):157-9.
1992: Winzen R; Wallach D; Engelmann H; Nophar Y; Brakebusch C; Kemper O; Resch K; Holtmann H
Selective decrease in cell surface expression and mRNA level of the 55-kDa tumor necrosis factor receptor during differentiation of HL-60 cells into macrophage-like but not granulocyte-like cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(11):3454-60.
1992: Brakebusch C; Nophar Y; Kemper O; Engelmann H; Wallach D
Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor.
The EMBO journal 1992;11(3):943-50.
1992: Aderka D; Engelmann H; Maor Y; Brakebusch C; Wallach D
Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors.
The Journal of experimental medicine 1992;175(2):323-9.
1991: Porteu F; Brockhaus M; Wallach D; Engelmann H; Nathan C F
Human neutrophil elastase releases a ligand-binding fragment from the 75-kDa tumor necrosis factor (TNF) receptor. Comparison with the proteolytic activity responsible for shedding of TNF receptors from stimulated neutrophils.
The Journal of biological chemistry 1991;266(28):18846-53.
1991: Aderka D; Englemann H; Hornik V; Skornick Y; Levo Y; Wallach D; Kushtai G
Increased serum levels of soluble receptors for tumor necrosis factor in cancer patients.
Cancer research 1991;51(20):5602-7.
1991: Kemper O; Derré J; Cherif D; Engelmann H; Wallach D; Berger R
The gene for the type II (p75) tumor necrosis factor receptor (TNF-RII) is localized on band 1p36.2-p36.3.
Human genetics 1991;87(5):623-4.
1991: König M; Wallach D; Resch K; Holtmann H
Induction of hyporesponsiveness to an early post-binding effect of tumor necrosis factor by tumor necrosis factor itself and interleukin 1.
European journal of immunology 1991;21(7):1741-5.
1991: Derré J; Kemper O; Cherif D; Nophar Y; Berger R; Wallach D
The gene for the type 1 tumor necrosis factor receptor (TNF-R1) is localized on band 12p13.
Human genetics 1991;87(2):231-3.
1991: Sarov I; Geron E; Shemer-Avni Y; Manor E; Zvillich M; Wallach D; Schmitz E; Holtman H
Implications for persistent chlamydial infections of phagocyte-microorganism interplay.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1991;10(2):119-23.
1991: Holtmann H; Brakebusch C; König M; Klocke R; Winzen R; Resch K; Wallach D
Mechanisms controlling the level of receptors for tumor necrosis factor.
Agents and actions 1991;32(1-2):106-8.
1991: Wallach D; Engelmann H; Nophar Y; Aderka D; Kemper O; Hornik V; Holtmann H; Brakebusch C
Soluble and cell surface receptors for tumor necrosis factor.
Agents and actions. Supplements 1991;35():51-7.
1990: Holtmann H; Shemer-Avni Y; Wessel K; Sarov I; Wallach D
Inhibition of growth of Chlamydia trachomatis by tumor necrosis factor is accompanied by increased prostaglandin synthesis.
Infection and immunity 1990;58(10):3168-72.
1990: Nophar Y; Kemper O; Brakebusch C; Englemann H; Zwang R; Aderka D; Holtmann H; Wallach D
Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor.
The EMBO journal 1990;9(10):3269-78.
1990: Engelmann H; Holtmann H; Brakebusch C; Avni Y S; Sarov I; Nophar Y; Hadas E; Leitner O; Wallach D
Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity.
The Journal of biological chemistry 1990;265(24):14497-504.
1990: Novick D; Engelmann H; Wallach D; Leitner O; Revel M; Rubinstein M
Purification of soluble cytokine receptors from normal human urine by ligand-affinity and immunoaffinity chromatography.
Journal of chromatography 1990;510():331-7.
1990: Yuhas Y; Holtmann H; Shemer-Avni Y; Sarov I; Wallach D
Inhibition of tumor necrosis factor-induced cell killing by tryptophan and indole.
European cytokine network 1990;1(1):35-40.
1990: Engelmann H; Novick D; Wallach D
Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors.
The Journal of biological chemistry 1990;265(3):1531-6.
1989: Israël A; Le Bail O; Hatat D; Piette J; Kieran M; Logeat F; Wallach D; Fellous M; Kourilsky P
TNF stimulates expression of mouse MHC class I genes by inducing an NF kappa B-like enhancer binding activity which displaces constitutive factors.
The EMBO journal 1989;8(12):3793-800.
1989: Shemer-Avni Y; Wallach D; Sarov I
Reversion of the antichlamydial effect of tumor necrosis factor by tryptophan and antibodies to beta interferon.
Infection and immunity 1989;57(11):3484-90.
1989: Novick D; Engelmann H; Wallach D; Rubinstein M
Soluble cytokine receptors are present in normal human urine.
The Journal of experimental medicine 1989;170(4):1409-14.
1989: Engelmann H; Aderka D; Rubinstein M; Rotman D; Wallach D
A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity.
The Journal of biological chemistry 1989;264(20):11974-80.
1989: Wallach D; Holtmann H; Aderka D; Rubinstein M; Avni Y S; Sarov I; Engelman H
Mechanisms which take part in regulation of the response to tumor necrosis factor.
Lymphokine research 1989;8(3):359-63.
1988: Ophir D; Hahn T; Schattner A; Wallach D; Aviel A
Tumor necrosis factor in middle ear effusions.
Archives of otolaryngology--head & neck surgery 1988;114(11):1256-8.
1988: Shemer-Avni Y; Wallach D; Sarov I
Inhibition of Chlamydia trachomatis growth by recombinant tumor necrosis factor.
Infection and immunity 1988;56(9):2503-6.
1988: Wallach D; Holtmann H; Engelmann H; Nophar Y
Sensitization and desensitization to lethal effects of tumor necrosis factor and IL-1.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(9):2994-9.
1988: Wallach D; Holtmann H; Aderka D; Hahn T; Engelmann H; Nophar Y
Sensitizing effects and mechanisms of desensitization in regulation of the in vivo response to TNF.
Annales de l'Institut Pasteur. Immunology 1988;139(3):323-7.
1988: Nophar Y; Holtmann H; Ber R; Wallach D
Dominance of resistance to the cytocidal effect of tumor necrosis factor in heterokaryons formed by fusion of resistant and sensitive cells.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(10):3456-60.
1988: Holtmann H; Hahn T; Wallach D
Interrelated effects of tumor necrosis factor and interleukin 1 on cell viability.
Immunobiology 1988;177(1):7-22.
1988: Korn J H; Mory Y; Ziberstein A; Holtmann H; Revel M; Wallach D
Cloning of genomic DNA for tumor necrosis factor and efficient expression in CHO cells.
Lymphokine research 1988;7(4):349-58.
1987: Aderka D; Levo Y; Ramot B; Michalevicz R; Meytes D; Shaklai M; Hahn T; Holtmann H; Revel M; Wallach D
Reduced production of tumor necrosis factor by mononuclear cells in hairy cell leukemia patients and improvement following interferon therapy.
Cancer 1987;60(9):2208-12.
1987: Holtmann H; Wallach D
Down regulation of the receptors for tumor necrosis factor by interleukin 1 and 4 beta-phorbol-12-myristate-13-acetate.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(4):1161-7.
1986: Aderka D; Holtmann H; Toker L; Hahn T; Wallach D
Tumor necrosis factor induction by Sendai virus.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(8):2938-42.
1986: Israel S; Hahn T; Holtmann H; Wallach D
Binding of human TNF-alpha to high-affinity cell surface receptors: effect of IFN.
Immunology letters 1986;12(4):217-24.
1986: Wallach D
Cytotoxins (tumour necrosis factor, lymphotoxin and others): molecular and functional characteristics and interactions with interferons.
Interferon 1986;7():89-124.
1985: Aderka D; Levo Y; Rahmani R; Mory Y; Vaks B; Horowitz O; Doerner T; Shoham J; Wallach D; Revel M
Rapid improvement in a terminal case of hairy cell leukemia treated with a new human recombinant interferon, IFN-alpha-C.
Israel journal of medical sciences 1985;21(12):977-81.
1985: Aderka D; Fisher S; Levo Y; Holtmann H; Hahn T; Wallach D
Cachectin/tumour-necrosis-factor production by cancer patients.
Lancet 1985;2(8465):1190.
1985: Hahn T; Toker L; Budilovsky S; Aderka D; Eshhar Z; Wallach D
Use of monoclonal antibodies to a human cytotoxin for its isolation and for examining the self-induction of resistance to this protein.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(11):3814-8.
1985: Aderka D; Novick D; Hahn T; Fischer D G; Wallach D
Increase of vulnerability to lymphotoxin in cells infected by vesicular stomatitis virus and its further augmentation by interferon.
Cellular immunology 1985;92(2):218-25.
1985: Schoenfeld A; Ovadia J; Levavi C; Nitke S; Wallach D; Schattner A; Revel M
Identification of viral infections in pregnancy by assay of (2'-5')-oligo-isoadenylate synthetase.
Early human development 1985;10(3-4):279-86.
1985: Aderka D; Hahn T; Wallach D
Involvement of cytotoxins in the immune response to viral infection.
Antiviral research 1985;Suppl 1():141-8.
1984: Wallach D; Hahn T; Budilovsky S
Translation of mRNA for human lymphotoxin in microinjected Xenopus oocytes.
FEBS letters 1984;178(2):257-63.
1984: Schattner A; Merlin G; Bregman V; Hahn T; Levin S; Revel M; Wallach D
(2'-5') Oligo A synthetase in human polymorphonuclear cells increased activity in interferon treatment and in viral infections.
Clinical and experimental immunology 1984;57(2):265-70.
1984: Shoham J; Cohen M; Wallach D
An immunoenzyme quantitative assay for the antiviral effect of interferons.
Journal of immunological methods 1984;72(1):279-87.
1984: Wallach D
Preparations of lymphotoxin induce resistance to their own cytotoxic effect.
Journal of immunology (Baltimore, Md. : 1950) 1984;132(5):2464-9.
1984: Gazitt Y; Ben-Bassat H; Wallach D; Revel M; Schattner A
Interferon-induced cytotoxicity and (2'-5') oligo(A) synthetase activity in T cells. Differences in responsiveness among T cells from various individuals and among lymphoblastoid T-cell lines.
Clinical immunology and immunopathology 1984;30(1):71-9.
1983: Wallach D
The HLA proteins and a related protein of 28 kDa are preferentially induced by interferon-gamma in human WISH cells.
European journal of immunology 1983;13(10):794-8.
1983: Wallach D
Quantification of the antiviral effect of interferon by immunoassay of vesicular stomatitis virus proteins.
The Journal of general virology 1983;64 (Pt 10)():2221-7.
1983: Wallach D; Hahn T
Enhanced release of lymphotoxins by interferon-treated cells.
Cellular immunology 1983;76(2):390-6.
1983: Wallach D
Interferon-induced resistance to the killing by NK cells: a preferential effect of IFN-gamma.
Cellular immunology 1983;75(2):390-5.
1983: Rosa F; Hatat D; Abadie A; Wallach D; Revel M; Fellous M
Differential regulation of HLA-DR mRNAs and cell surface antigens by interferon.
The EMBO journal 1983;2(9):1585-9.
1982: Zor U; Ben-Dori R; Maoz I; Wallach D; Gurari-Rotman D
Inhibition by glucocorticosteroid hormones of interferon and prostaglandin E induction by poly(rI). Poly(rC).
The Journal of general virology 1982;63(2):359-63.
1982: Wallach D; Fellous M; Revel M
Preferential effect of gamma interferon on the synthesis of HLA antigens and their mRNAs in human cells.
Nature 1982;299(5886):833-6.
1982: Schattner A; Meshorer A; Revel M; Wallach D
Interferon as a possible cause for virus-related lymphocytopenia.
Israel journal of medical sciences 1982;18(9):965-6.
1982: Fellous M; Nir U; Wallach D; Merlin G; Rubinstein M; Revel M
Interferon-dependent induction of mRNA for the major histocompatibility antigens in human fibroblasts and lymphoblastoid cells.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(10):3082-6.
1982: Schattner A; Wallach D; Merlin G; Hahn T; Levin S; Ramot B; Revel M
Variation of (2'-5') oligo A synthetase level in lymphocytes and granulocytes of patients with viral infections and leukemia.
Journal of interferon research 1982;2(3):355-61.
1982: Wallach D
Regulation of susceptibility to natural killer cells' cytotoxicity and regulation of HLA synthesis: differing efficacies of alpha, beta, and gamma interferons.
Journal of interferon research 1982;2(3):329-38.
1982: Schattner A; Merlin G; Shapira A; Revel M; Wallach D
Comparison of (2'-5') oligo-adenylate synthetase and interferon blood-levels in mice early after viral infection.
Journal of interferon research 1982;2(2):285-9.
1981: Schattner A; Wallach D; Merlin G; Hahn T; Levin S; Revel M
Assay of an interferon-induced enzyme in white blood cells as a diagnostic aid in viral diseases.
Lancet 1981;2(8245):497-500.
1981: Merlin G; Revel M; Wallach D
The interferon-induced enzyme oligo-isoadenylate synthetase: rapid determination of its in vitro products.
Analytical biochemistry 1981;110(1):190-6.
1981: Schattner A; Merlin G; Wallach D; Rosenberg H; Bino T; Hahn T; Levin S; Revel M
Monitoring of interferon therapy by assay of (2'--5') oligo-isoadenylate synthetase in human peripheral white blood cells.
Journal of interferon research 1981;1(4):587-94.
1981: Revel M; Wallach D; Merlin G; Schattner A; Schmidt A; Wolf D; Shulman L; Kimchi A
Interferon-induced enzymes: microassays and their applications: purification and assay of (2'-5')-oligoadenylate synthetase and assay of 2'-phosphodiesterase.
Methods in enzymology 1981;79(Pt B):149-61.
1980: Weissenbach J; Chernajovsky Y; Zeevi M; Shulman L; Soreq H; Nir U; Wallach D; Perricaudet M; Tiollais P; Revel M
Two interferon mRNAs in human fibroblasts: in vitro translation and Escherichia coli cloning studies.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(12):7152-6.
1980: Wallach D; Revel M
An interferon-induced cellular enzyme is incorporated into virions.
Nature 1980;287(5777):68-70.
1980: Davies P J; Wallach D; Willingham M; Pastan I; Lewis M S
Self-association of chicken gizzard filamin and heavy merofilamin.
Biochemistry 1980;19(7):1366-72.
1979: Wallach D; Revel M
Hormonal protection of interferon-treated cells against double-stranded RNA-induced cytolysis.
FEBS letters 1979;101(2):364-8.
1978: Wallach D; Davies P J; Pastan I
Cyclic AMP-dependent phosphorylation of filamin in mammalian smooth muscle.
The Journal of biological chemistry 1978;253(13):4739-45.
1978: Davies P J; Wallach D; Willingham M C; Pastan I; Yamaguchi M; Robson R M
Filamin-actin interaction. Dissociation of binding from gelation by Ca2+-activated proteolysis.
The Journal of biological chemistry 1978;253(11):4036-42.
1978: Wallach D; Davies P J; Pastan I
Purification of mammalian filamin. Similarity to high molecular weight actin-binding protein in macrophages, platelets, fibroblasts, and other tissues.
The Journal of biological chemistry 1978;253(9):3228-35.
1978: Wallach D; Anderson W; Pastan I
Activation of adenylate cyclase in cultured fibroblasts by trypsin.
The Journal of biological chemistry 1978;253(1):24-6.
1978: Wallach D; Davies P; Bechtel P; Willingham M; Pastan I
Cyclic AMP-dependent phosphorylation of the actin-binding protein filamin.
Advances in cyclic nucleotide research 1978;9():371-9.
1976: Wallach D; Pastan I
Stimulation of membranous guanylate cyclase by concentrations of calcium that are in the physiological range.
Biochemical and biophysical research communications 1976;72(3):859-65.
1976: Wallach D; Pastan I
Stimulation of guanylate cyclase of fibroblasts by free fatty acids.
The Journal of biological chemistry 1976;251(18):5802-9.
1975: Wallach D; Tessler R; Schramm M
The proteins of the content of the secretory granules of the rat parotid gland.
Biochimica et biophysica acta 1975;382(4):552-64.
1975: Wallach D; Kirshner N; Schramm M
Non-parallel transport of membrane proteins and content proteins during assembly of the secretory granule in rat parotid gland.
Biochimica et biophysica acta 1975;375(1):87-105.
1973: Kirshner N; Wallach D; Sharoni Y; Schramm M
Purification of secretory granules on a urografin gradient.
Analytical biochemistry 1973;52(2):589-94.
1972: Bar-Nun S; Wallach D; Ohad I
Biogenesis of chloroplast membranes. X. Changes in the photosynthetic specific activity and the relationship between the light harvesting system and photosynthetic electron transfer chain during greening of Chlamydomonas reinhardi y-1 cells.
Biochimica et biophysica acta 1972;267(1):138-48.
1972: Wallach D; Bar-Nun S; Ohad I
Biogenesis of chloroplast membranes. IX. Development of photophosphorylation and proton pump activities in greening Chlamydomonas reinhardi y-I as measured with an open-cell preparation.
Biochimica et biophysica acta 1972;267(1):125-37.
1971: Wallach D; Schramm M
Calcium and the exportable protein in rat parotid gland. Parallel subcellular distribution and concomitant secretion.
European journal of biochemistry / FEBS 1971;21(3):433-7.

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