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dante rotili

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Andrea Galmozzi; Elise Gers; Federica Gilardi; Cristina Godio; Alice Gualerzi; Uliano Guerrini; Antonello Mai; Nico Mitro; dante rotili; Enrique Saez; Sergio Valente; Donatella Caruso; Gaia Cermenati; Emma De Fabiani; Elena Donetti; Alessandra Ferrari; Maurizio Crestani
Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue.
dante rotili; Christian Steinkühler; Domenico Tarantino; Paolo Mellini; Angela Nebbioso; Chantal Paolini; Riccardo Pezzi; Antti Poso; Lucia Altucci; Giorgia Botta; Ruggero De Maria; Manel Esteller; Mario Fraga; paola gallinari; Covadonga Huidobro; Maija Lahtela-Kakkonen; Ester Lara; Alessia Lenoci; Antonello Mai
Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells.
dante rotili; Jörg Schemies; Christian Steinkühler; Domenico Tarantino; Ettore Novellino; Chantal Paolini; Lucia Altucci; Giorgia Botta; Vincenzo Carafa; Ruggero De Maria; Salvatore Di Maro; paola gallinari; Manfred Jung; Antonello Mai
Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells.

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All Publications

2013: Andrea Galmozzi; Elise Gers; Federica Gilardi; Cristina Godio; Alice Gualerzi; Uliano Guerrini; Antonello Mai; Nico Mitro; dante rotili; Enrique Saez; Sergio Valente; Donatella Caruso; Gaia Cermenati; Emma De Fabiani; Elena Donetti; Alessandra Ferrari; Maurizio Crestani
Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue.
Diabetes 2013;62(3):732-42.
2012: dante rotili; Christian Steinkühler; Domenico Tarantino; Paolo Mellini; Angela Nebbioso; Chantal Paolini; Riccardo Pezzi; Antti Poso; Lucia Altucci; Giorgia Botta; Ruggero De Maria; Manel Esteller; Mario Fraga; paola gallinari; Covadonga Huidobro; Maija Lahtela-Kakkonen; Ester Lara; Alessia Lenoci; Antonello Mai
Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells.
Journal of medicinal chemistry 2012;55(24):10937-47.
2012: dante rotili; Jörg Schemies; Christian Steinkühler; Domenico Tarantino; Ettore Novellino; Chantal Paolini; Lucia Altucci; Giorgia Botta; Vincenzo Carafa; Ruggero De Maria; Salvatore Di Maro; paola gallinari; Manfred Jung; Antonello Mai
Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells.
Journal of medicinal chemistry 2012;55(18):8193-7.
2012: Wei Wei; Shanzhi Yan; Shawn Anderson; Sabrina Castellano; Carlos M Coelho; Philip A Cole; Michael S Kobor; Xiang Li; Antonello Mai; Roger Marek; DAVID MEYERS; Ciro Milite; Chandrani Mukherjee; dante rotili; Pankaj Sah; Gianluca Sbardella; Timothy W Bredy
p300/CBP-associated factor selectively regulates the extinction of conditioned fear.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(35):11930-41.
2012: dante rotili; Alberta Samuele; Domenico Tarantino; Ludovica Morera; Ira Musmuca; Maxim B Nawrozkij; Marco Pierini; Rino Ragno; Marino Artico; FLAVIO BALLANTE; Giorgia Botta; Roberto Cirilli; Bonaventura Clotet; José A Esté; Emmanuel Gonzalez; giovanni maga; Antonello Mai
2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies.
Journal of medicinal chemistry 2012;55(7):3558-62.
2012: Anup K Upadhyay; Young-Sup Yoon; Xing Zhang; Yanqi Chang; Ji Woong Han; Ruogu Hu; Donatella Labella; Antonello Mai; dante rotili; Xiaodong Cheng
An analog of BIX-01294 selectively inhibits a family of histone H3 lysine 9 Jumonji demethylases.
Journal of molecular biology 2012;416(3):319-27.
2011: Gianluca Sbardella; Ilaria Sciamanna; Annalucia Serafino; Sara Bartolini; Sabrina Castellano; Roberto Cirilli; Patrizia Lavia; Antonello Mai; Ciro Milite; Serena Orlando; dante rotili; Marisabella Santoriello; Corrado Spadafora
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors.
Journal of medicinal chemistry 2011;54(16):5927-36.
2011: dante rotili; Domenico Tarantino; Angela Nebbioso; Lucia Altucci; Giorgia Botta; Vincenzo Carafa; Antonello Mai
Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile.
Bioorganic & medicinal chemistry 2011;19(12):3659-68.
2011: dante rotili; Antonello Mai
Targeting Histone Demethylases: A New Avenue for the Fight against Cancer.
Genes & cancer 2011;2(6):663-79.
2011: dante rotili; Mikael Altun; Akane Kawamura; Alexander Wolf; Roman Fischer; Ivanhoe K H Leung; Mukram M Mackeen; Ya-Min Tian; Peter J Ratcliffe; Antonello Mai; Benedikt M Kessler; Christopher J Schofield
A photoreactive small-molecule probe for 2-oxoglutarate oxygenases.
Chemistry & biology 2011;18(5):642-54.
2011: Maria Meli; Manlio Tolomeo; Mario Grifantini; Antonello Mai; Loredana Cappellacci; Riccardo Petrelli; dante rotili; Arianna Ferro; Philipp Saiko; Thomas Szekeres; Luisa Dusonchet
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells.
International journal of oncology 2011;38(5):1427-36.
2011: dante rotili; Alberta Samuele; Domenico Tarantino; Maxim B Nawrozkij; Marino Artico; Bonaventura Clotet; José A Esté; Emmanuel Gonzalez-Ortega; giovanni maga; Antonello Mai
Diarylpyrimidine-dihydrobenzyloxopyrimidine hybrids: new, wide-spectrum anti-HIV-1 agents active at (sub)-nanomolar level.
Journal of medicinal chemistry 2011;54(8):3091-6.
2011: Luciana Mosca; dante rotili; Italo Tempera; Alessandra Masci; Mario Fontana; Roberta Chiaraluce; Paola Mastromarino; Maria D'Erme; Antonello Mai
Biological effects of MC2050, a quinazoline-based PARP-1 inhibitor, in human neuroblastoma and EBV-positive Burkitt's lymphoma cells.
ChemMedChem 2011;6(4):606-11.
2011: dante rotili; Mikael Altun; Refaat B Hamed; Christoph Loenarz; Armin Thalhammer; Richard J Hopkinson; Ya-Min Tian; Peter J Ratcliffe; Antonello Mai; Benedikt M Kessler; Christopher J Schofield
Photoactivable peptides for identifying enzyme-substrate and protein-protein interactions.
Chemical communications (Cambridge, England) 2011;47(5):1488-90.
2010: Angela Nebbioso; Carmela Dell'Aversana; Anne Bugge; Roberta Sarno; Sergio Valente; dante rotili; Fabio Manzo; Diana Teti; Susanne Mandrup; Paolo Ciana; Adriana Maggi; Antonello Mai; Hinrich Gronemeyer; Lucia Altucci
HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation.
Journal of molecular endocrinology 2010;45(4):219-28.
2010: Claudia Colussi; Rodolfo Berni; Jessica Rosati; Stefania Straino; Serena Vitale; Francesco Spallotta; Silvana Baruffi; Leonardo Bocchi; Francesca Delucchi; Stefano Rossi; Monia Savi; dante rotili; Federico Quaini; Emilio Macchi; Donatella Stilli; Ezio Musso; Antonello Mai; carlo gaetano; Maurizio C Capogrossi
The histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces cardiac arrhythmias in dystrophic mice.
Cardiovascular research 2010;87(1):73-82.
2010: dante rotili; Domenico Tarantino; Vincenzo Carafa; Ester Lara; Sarah Meade; Giorgia Botta; Angela Nebbioso; Jörg Schemies; Manfred Jung; Aleksey G Kazantsev; Manel Esteller; Mario F Fraga; Lucia Altucci; Antonello Mai
Identification of tri- and tetracyclic pyrimidinediones as sirtuin inhibitors.
ChemMedChem 2010;5(5):674-7.
2010: Francesco Spallotta; Jessica Rosati; Stefania Straino; Simona Nanni; Annalisa Grasselli; Valeria Ambrosino; dante rotili; Sergio Valente; Antonella Farsetti; Antonello Mai; Maurizio C Capogrossi; carlo gaetano; Barbara Illi
Nitric oxide determines mesodermic differentiation of mouse embryonic stem cells by activating class IIa histone deacetylases: potential therapeutic implications in a mouse model of hindlimb ischemia.
Stem cells (Dayton, Ohio) 2010;28(3):431-42.
2010: Matthieu Y Pasco; dante rotili; Lucia Altucci; Francesca Farina; Guy Rouleau; Antonello Mai; Christian Néri
Characterization of sirtuin inhibitors in nematodes expressing a muscular dystrophy protein reveals muscle cell and behavioral protection by specific sirtinol analogues.
Journal of medicinal chemistry 2010;53(3):1407-11.
2010: C Colussi; C Banfi; M Brioschi; E Tremoli; Stefania Straino; F Spallotta; Antonello Mai; dante rotili; Maurizio C Capogrossi; carlo gaetano
Proteomic profile of differentially expressed plasma proteins from dystrophic mice and following suberoylanilide hydroxamic acid treatment.
Proteomics. Clinical applications 2010;4(1):71-83.
2010: Luisa Quinti; Vanita Chopra; dante rotili; Sergio Valente; Allison Amore; Gianluigi Franci; Sarah Meade; Marta Valenza; Lucia Altucci; Michele M Maxwell; Elena Cattaneo; Steven M Hersch; Antonello Mai; Aleksey Kazantsev
Evaluation of histone deacetylases as drug targets in Huntington's disease models. Study of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients and in a neuronal HD cell model.
PLoS currents 2010;2():.
2009: E Lara; A Mai; Vincenzo Calvanese; L Altucci; P Lopez-Nieva; M L Martinez-Chantar; M Varela-Rey; dante rotili; A Nebbioso; Santiago Ropero; G Montoya; J Oyarzabal; S Velasco; M Serrano; M Witt; Ana Villar-Garea; A Imhof; A Inhof; J M Mato; Manel Esteller; Mario F Fraga
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.
Oncogene 2009;28(6):781-91.
2009: Antonello Mai; dante rotili; Sergio Valente; Aleksey G Kazantsev
Histone deacetylase inhibitors and neurodegenerative disorders: holding the promise.
Current pharmaceutical design 2009;15(34):3940-57.