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Yi Xing

Research Profile

Chemicals & Drugs

Devices

Oligonucleotide Array Sequence Analysis

Procedures

Phenomena

Evolution, Molecular

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Databases, Genetic

Genes & Molecular Sequences

Genome, Human

Physiology

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Publications

TOP 3
Shyam Ramachandran; Scott D Rose; Amy E Walz; Michael J Welsh; Yi Xing; Lynda S Ostedgaard; Mark A Behlke; John T Fisher; Ashley M Jacobi; Peng Jiang; Philip H Karp; Shaf Keshavjee; Kim A Lennox; Paul B McCray
A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator.
Zhi-Xiang Lu; Peng Jiang; Yi Xing
Genetic variation of pre-mRNA alternative splicing in human populations.
Shihao Shen; Qing Zhou; Russ P Carstens; Kimberly A Dittmar; Jian Huang; Zhi-xiang Lu; Juw Won Park; Yi Xing
MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data.

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All Publications

2012: Shyam Ramachandran; Scott D Rose; Amy E Walz; Michael J Welsh; Yi Xing; Lynda S Ostedgaard; Mark A Behlke; John T Fisher; Ashley M Jacobi; Peng Jiang; Philip H Karp; Shaf Keshavjee; Kim A Lennox; Paul B McCray
A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(33):13362-7.
2012: Zhi-Xiang Lu; Peng Jiang; Yi Xing
Genetic variation of pre-mRNA alternative splicing in human populations.
Wiley interdisciplinary reviews. RNA 2012;3(4):581-92.
2012: Shihao Shen; Qing Zhou; Russ P Carstens; Kimberly A Dittmar; Jian Huang; Zhi-xiang Lu; Juw Won Park; Yi Xing
MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data.
Nucleic acids research 2012;40(8):e61.
2012: Jinsil Kim; Zhi-xiang Lu; Jeffrey C Murray; Jinkai Wang; Peng Jiang; Keyan Zhao; Yi Xing
Transcriptome landscape of the human placenta.
BMC genomics 2012;13():115.
2011: Weihong Xu; Junhee Seok; Michael N Mindrinos; Anthony C Schweitzer; Hui Jiang; Julie Wilhelmy; Tyson A Clark; Karen Kapur; Yi Xing; Malek Faham; John D Storey; Lyle L Moldawer; Ronald V Maier; Ronald G Tompkins; Wing Hung Wong; Ronald W Davis; wenzhong xiao
Human transcriptome array for high-throughput clinical studies.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(9):3707-12.
2011: Shihao Shen; Lan Lin; James J Cai; Peng Jiang; Elizabeth J Kenkel; Mallory R Stroik; Seiko Sato; Beverly L Davidson; Yi Xing
Widespread establishment and regulatory impact of Alu exons in human genes.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(7):2837-42.
2011: Song Liu; Lan Lin; Peng Jiang; Dan Wang; Yi Xing
A comparison of RNA-Seq and high-density exon array for detecting differential gene expression between closely related species.
Nucleic acids research 2011;39(2):578-88.
2010: Kin Fai Au; Hui Jiang; Lan Lin; Yi Xing; Wing Hung Wong
Detection of splice junctions from paired-end RNA-seq data by SpliceMap.
Nucleic acids research 2010;38(14):4570-8.
2010: Shihao Shen; Claude C Warzecha; Russ P Carstens; Yi Xing
MADS+: discovery of differential splicing events from Affymetrix exon junction array data.
Bioinformatics (Oxford, England) 2010;26(2):268-9.
2009: Glen M Borchert; Brian L Gilmore; Ryan M Spengler; Yi Xing; William Lanier; Debashish Bhattacharya; Beverly L Davidson
Adenosine deamination in human transcripts generates novel microRNA binding sites.
Human molecular genetics 2009;18(24):4801-7.
2009: Hongchao Lu; Lan Lin; Seiko Sato; Yi Xing; Christopher J Lee
Predicting functional alternative splicing by measuring RNA selection pressure from multigenome alignments.
PLoS computational biology 2009;5(12):e1000608.
2009: Lan Lin; Song Liu; Heather Brockway; Junhee Seok; Peng Jiang; Wing Hung Wong; Yi Xing
Using high-density exon arrays to profile gene expression in closely related species.
Nucleic acids research 2009;37(12):e90.
2009: Ryan L Boudreau; Jodi L McBride; Inês Martins; Shihao Shen; Yi Xing; Barrie J Carter; Beverly L Davidson
Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(6):1053-63.
2008: Dubinsky N Amy; Yi Xing; Scott Q Harper; Lesley Jones; Beverly L Davidson
The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(53):14341-6.
2008: Karen Kapur; Hui Jiang; Yi Xing; Wing Hung Wong
Cross-hybridization modeling on Affymetrix exon arrays.
Bioinformatics (Oxford, England) 2008;24(24):2887-93.
2008: Meenakshi Roy; Namshin Kim; Yi Xing; Christopher Lee
The effect of intron length on exon creation ratios during the evolution of mammalian genomes.
RNA (New York, N.Y.) 2008;14(11):2261-73.
2008: Yi Xing; Peter Stoilov; Karen Kapur; Areum Han; Hui Jiang; Shihao Shen; Douglas L Black; Wing Hung Wong
MADS: a new and improved method for analysis of differential alternative splicing by exon-tiling microarrays.
RNA (New York, N.Y.) 2008;14(8):1470-9.
2008: Eric Chiao; Menashe Elazar; Yi Xing; Anming Xiong; Muriel Kmet; Maria T Millan; Jeffrey S Glenn; Wing H Wong; Julie Baker
Isolation and transcriptional profiling of purified hepatic cells derived from human embryonic stem cells.
Stem cells (Dayton, Ohio) 2008;26(8):2032-41.
2008: John D Cahoy; Ben Emery; Amit Kaushal; Lynette C Foo; Jennifer L Zamanian; Karen S Christopherson; Yi Xing; Jane L Lubischer; Paul A Krieg; Sergey A Krupenko; Wesley J Thompson; Ben A Barres
A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(1):264-78.
2008: Lan Lin; Shihao Shen; Anne Tye; James J Cai; Peng Jiang; Beverly L Davidson; Yi Xing
Diverse splicing patterns of exonized Alu elements in human tissues.
PLoS genetics 2008;4(10):e1000225.
2007: John A Calarco; Yi Xing; Mario Cáceres; Joseph P Calarco; Xinshu Xiao; Qun Pan; Christopher Lee; Todd M Preuss; Benjamin J Blencowe
Global analysis of alternative splicing differences between humans and chimpanzees.
Genes & development 2007;21(22):2963-75.
2007: Yi Xing; Zhengqing Ouyang; Karen Kapur; Matthew P Scott; Wing Hung Wong
Assessing the conservation of mammalian gene expression using high-density exon arrays.
Molecular biology and evolution 2007;24(6):1283-5.
2007: Ji-Ann Lee; Yi Xing; David Nguyen; Jiuyong Xie; Christopher J Lee; Douglas L Black
Depolarization and CaM kinase IV modulate NMDA receptor splicing through two essential RNA elements.
PLoS biology 2007;5(2):e40.
2007: Karen Kapur; Yi Xing; Zhengqing Ouyang; Wing Hung Wong
Exon arrays provide accurate assessments of gene expression.
Genome biology 2007;8(5):R82.
2006: Yi Xing; Christopher Lee
Alternative splicing and RNA selection pressure--evolutionary consequences for eukaryotic genomes.
Nature reviews. Genetics 2006;7(7):499-509.
2006: Yi Xing; Qi Wang; Christopher Lee
Evolutionary divergence of exon flanks: a dissection of mutability and selection.
Genetics 2006;173(3):1787-91.
2006: Yi Xing; Christopher Lee
Can RNA selection pressure distort the measurement of Ka/Ks?
Gene 2006;370():1-5.
2006: Yi Xing; Karen Kapur; Wing Hung Wong
Probe selection and expression index computation of Affymetrix Exon Arrays.
PloS one 2006;1():e88.
2005: Yi Xing; Christopher Lee
Evidence of functional selection pressure for alternative splicing events that accelerate evolution of protein subsequences.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13526-31.
2005: Yi Xing; Christopher J Lee
Protein modularity of alternatively spliced exons is associated with tissue-specific regulation of alternative splicing.
PLoS genetics 2005;1(3):e34.
2004: Yi Xing; Christopher J Lee
Negative selection pressure against premature protein truncation is reduced by alternative splicing and diploidy.
Trends in genetics : TIG 2004;20(10):472-5.
2004: Yi Xing; Alissa Resch; Christopher Lee
The multiassembly problem: reconstructing multiple transcript isoforms from EST fragment mixtures.
Genome research 2004;14(3):426-41.
2004: Alissa Resch; Yi Xing; Barmak Modrek; Michael Gorlick; Robert Riley; Christopher Lee
Assessing the impact of alternative splicing on domain interactions in the human proteome.
Journal of proteome research 2004;3(1):76-83.
2004: Alissa Resch; Yi Xing; Alexander Alekseyenko; Barmak Modrek; Christopher Lee
Evidence for a subpopulation of conserved alternative splicing events under selection pressure for protein reading frame preservation.
Nucleic acids research 2004;32(4):1261-9.
2003: Yi Xing; Qiang Xu; Christopher Lee
Widespread production of novel soluble protein isoforms by alternative splicing removal of transmembrane anchoring domains.
FEBS letters 2003;555(3):572-8.
2003: Amani Zewail; Michael W Xie; Yi Xing; Lan Lin; P Fred Zhang; Wei Zou; Jonathan P Saxe; Jing Huang
Novel functions of the phosphatidylinositol metabolic pathway discovered by a chemical genomics screen with wortmannin.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3345-50.
2003: Christopher Lee; Levan Atanelov; Barmak Modrek; Yi Xing
ASAP: the Alternative Splicing Annotation Project.
Nucleic acids research 2003;31(1):101-5.