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Christine Heim

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Felicia Gould; Philip D Harvey; Christine Heim; Matthias Majer; Jennifer Clarke; Charles Nemeroff
The effects of child abuse and neglect on cognitive functioning in adulthood.
Boadie W Dunlop; Yara Betancourt; Elisabeth B Binder; Christine Heim; Florian Holsboer; Marcus Ising; Melissa McKenzie; Tanja Mletzko; Hildegard Pfister; Charles Nemeroff; W. Edward Craighead; Helen S Mayberg
Tolerability of the dexamethasone-corticotropin releasing hormone test in major depressive disorder.
Christine Heim; Margaret Shugart; W. Edward Craighead; Charles Nemeroff
Neurobiological and psychiatric consequences of child abuse and neglect.

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All Publications

2012: Felicia Gould; Philip D Harvey; Christine Heim; Matthias Majer; Jennifer Clarke; Charles Nemeroff
The effects of child abuse and neglect on cognitive functioning in adulthood.
Journal of psychiatric research 2012;46(4):500-6.
2011: Boadie W Dunlop; Yara Betancourt; Elisabeth B Binder; Christine Heim; Florian Holsboer; Marcus Ising; Melissa McKenzie; Tanja Mletzko; Hildegard Pfister; Charles Nemeroff; W. Edward Craighead; Helen S Mayberg
Tolerability of the dexamethasone-corticotropin releasing hormone test in major depressive disorder.
Journal of psychiatric research 2011;45(1):24-8.
2010: Christine Heim; Margaret Shugart; W. Edward Craighead; Charles Nemeroff
Neurobiological and psychiatric consequences of child abuse and neglect.
Developmental psychobiology 2010;52(7):671-90.
2010: Urs M Nater; James F Jones; Jin-Mann S Lin; Elizabeth Maloney; William C Reeves; Christine Heim
Personality features and personality disorders in chronic fatigue syndrome: a population-based study.
Psychotherapy and psychosomatics 2010;79(5):312-8.
2009: Katja Wingenfeld; Dirk H Hellhammer; Iris Schmidt; Dieter Wagner; Gunther Meinlschmidt; Christine Heim
HPA axis reactivity in chronic pelvic pain: association with depression.
Journal of psychosomatic obstetrics and gynaecology 2009;30(4):282-6.
2009: Urs M Nater; Toni Whistler; William Lonergan; Tanja Mletzko; Suzanne D Vernon; Christine Heim
Impact of acute psychosocial stress on peripheral blood gene expression pathways in healthy men.
Biological psychology 2009;82(2):125-32.
2009: Christine Heim; Larry J Young; D Jeffrey Newport; Tanja C Mletzko; Andrew H Miller; Charles Nemeroff
Lower CSF oxytocin concentrations in women with a history of childhood abuse.
Molecular psychiatry 2009;14(10):954-8.
2009: Urs M Nater; Jin-Mann S Lin; Elizabeth M Maloney; James F Jones; Hao Tian; Roumiana S Boneva; Charles L Raison; William C Reeves; Christine Heim
Psychiatric comorbidity in persons with chronic fatigue syndrome identified from the Georgia population.
Psychosomatic medicine 2009;71(5):557-65.
2009: Christine Heim; Bekh Bradley; Tanja C Mletzko; Todd C Deveau; Dominique L Musselman; Charles Nemeroff; Kerry J Ressler; Elisabeth B Binder
Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene.
Frontiers in behavioral neuroscience 2009;3():41.
2009: Christine Heim; Charles Nemeroff
Neurobiology of posttraumatic stress disorder.
CNS spectrums 2009;14(1 Suppl 1):13-24.
2009: Christine Heim; Urs M Nater; Elizabeth M Maloney; Roumiana Boneva; James F Jones; William C Reeves
Childhood trauma and risk for chronic fatigue syndrome: association with neuroendocrine dysfunction.
Archives of general psychiatry 2009;66(1):72-80.
2008: Christine Heim; D Jeffrey Newport; Tanja Mletzko; Andrew H Miller; Charles Nemeroff
The link between childhood trauma and depression: insights from HPA axis studies in humans.
Psychoneuroendocrinology 2008;33(6):693-710.
2008: Urs M Nater; Laura Solomon Youngblood; James F Jones; Elizabeth R Unger; Andrew H Miller; William C Reeves; Christine Heim
Alterations in diurnal salivary cortisol rhythm in a population-based sample of cases with chronic fatigue syndrome.
Psychosomatic medicine 2008;70(3):298-305.
2008: Elisabeth B Binder; Rebekah G Bradley; Wei Liu; Michael P Epstein; Todd C Deveau; Kristina B Mercer; Yilang Tang; Charles F Gillespie; Christine Heim; Charles Nemeroff; Ann C Schwartz; Joseph F Cubells; Kerry J Ressler
Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults.
JAMA : the journal of the American Medical Association 2008;299(11):1291-305.
2008: Urs M Nater; Elizabeth M Maloney; Roumiana S Boneva; Brian Gurbaxani; Jin-Mann Lin; James F Jones; William C Reeves; Christine Heim
Attenuated morning salivary cortisol concentrations in a population-based study of persons with chronic fatigue syndrome and well controls.
The Journal of clinical endocrinology and metabolism 2008;93(3):703-9.
2008: Christine Heim; Tanja C Mletzko; David Purselle; Dominique L Musselman; Charles Nemeroff
The dexamethasone/corticotropin-releasing factor test in men with major depression: role of childhood trauma.
Biological psychiatry 2008;63(4):398-405.
2008: Rebekah G Bradley; Elisabeth B Binder; Michael P Epstein; Yilang Tang; Hemu P Nair; Wei Liu; Charles F Gillespie; Tiina Berg; Mark Evces; D Jeffrey Newport; Zachary N Stowe; Christine Heim; Charles Nemeroff; Ann Schwartz; Joseph F Cubells; Kerry J Ressler
Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene.
Archives of general psychiatry 2008;65(2):190-200.
2008: Alicia K Smith; Irina M Dimulescu; Virginia R Falkenberg; Supraja Narasimhan; Christine Heim; Suzanne D Vernon; Mangalathu S Rajeevan
Genetic evaluation of the serotonergic system in chronic fatigue syndrome.
Psychoneuroendocrinology 2008;33(2):188-97.
2008: Katja Wingenfeld; Christine Heim; Iris Schmidt; Dieter Wagner; Gunther Meinlschmidt; Dirk H Hellhammer
HPA axis reactivity and lymphocyte glucocorticoid sensitivity in fibromyalgia syndrome and chronic pelvic pain.
Psychosomatic medicine 2008;70(1):65-72.
2007: Roumiana S Boneva; Michael J Decker; Elizabeth M Maloney; Jin-Mann Lin; James F Jones; Helgi G Helgason; Christine Heim; David B Rye; William C Reeves
Higher heart rate and reduced heart rate variability persist during sleep in chronic fatigue syndrome: a population-based study.
Autonomic neuroscience : basic & clinical 2007;137(1-2):94-101.
2007: Gunther Meinlschmidt; Christine Heim
Sensitivity to intranasal oxytocin in adult men with early parental separation.
Biological psychiatry 2007;61(9):1109-11.
2007: Jacqueline Laures-Gore; Christine Heim; Yu-Sheng Hsu
Assessing cortisol reactivity to a linguistic task as a marker of stress in individuals with left-hemisphere stroke and aphasia.
Journal of speech, language, and hearing research : JSLHR 2007;50(2):493-507.
2007: Mangalathu S Rajeevan; A K Smith; Irina M Dimulescu; Elizabeth R Unger; Suzanne D Vernon; Christine Heim; William C Reeves
Glucocorticoid receptor polymorphisms and haplotypes associated with chronic fatigue syndrome.
Genes, brain, and behavior 2007;6(2):167-76.
2007: Matthias Majer; James F Jones; Elizabeth R Unger; Laura Solomon Youngblood; Michael J Decker; Brian Gurbaxani; Christine Heim; William C Reeves
Perception versus polysomnographic assessment of sleep in CFS and non-fatigued control subjects: results from a population-based study.
BMC neurology 2007;7():40.
2007: William C Reeves; James F Jones; Elizabeth M Maloney; Christine Heim; David C Hoaglin; Roumiana S Boneva; Marjorie Morrissey; Rebecca Devlin
Prevalence of chronic fatigue syndrome in metropolitan, urban, and rural Georgia.
Population health metrics 2007;5():5.
2007: Katja Wingenfeld; Dieter Wagner; Iris Schmidt; Gunther Meinlschmidt; Dirk H Hellhammer; Christine Heim
The low-dose dexamethasone suppression test in fibromyalgia.
Journal of psychosomatic research 2007;62(1):85-91.
2006: Christine Heim; Dieter Wagner; Elizabeth M Maloney; Dimitris A Papanicolaou; Laura Solomon; James F Jones; Elizabeth R Unger; William C Reeves
Early adverse experience and risk for chronic fatigue syndrome: results from a population-based study.
Archives of general psychiatry 2006;63(11):1258-66.
2006: Thaddeus W W Pace; Tanja C Mletzko; Oyetunde Alagbe; Dominique L Musselman; Charles Nemeroff; Andrew H Miller; Christine Heim
Increased stress-induced inflammatory responses in male patients with major depression and increased early life stress.
The American journal of psychiatry 2006;163(9):1630-3.
2006: Lucile Capuron; Leonie Welberg; Christine Heim; Dieter Wagner; Laura Solomon; Dimitris A Papanicolaou; R. Cameron Craddock; Andrew H Miller; William C Reeves
Cognitive dysfunction relates to subjective report of mental fatigue in patients with chronic fatigue syndrome.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(8):1777-84.
2006: Urs M Nater; Dieter Wagner; Laura Solomon; James F Jones; Elizabeth R Unger; Dimitris A Papanicolaou; William C Reeves; Christine Heim
Coping styles in people with chronic fatigue syndrome identified from the general population of Wichita, KS.
Journal of psychosomatic research 2006;60(6):567-73.
2006: William C Reeves; Christine Heim; Elizabeth M Maloney; Laura Solomon Youngblood; Elizabeth R Unger; Michael J Decker; James F Jones; David B Rye
Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study.
BMC neurology 2006;6():41.
2005: James F Jones; Ainsley Nicholson; Rosane Nisenbaum; Dimitris A Papanicolaou; Laura Solomon; Roumiana S Boneva; Christine Heim; William C Reeves
Orthostatic instability in a population-based study of chronic fatigue syndrome.
The American journal of medicine 2005;118(12):1415.
2005: Dieter Wagner; Rosane Nisenbaum; Christine Heim; James F Jones; Elizabeth R Unger; William C Reeves
Psychometric properties of the CDC Symptom Inventory for assessment of chronic fatigue syndrome.
Population health metrics 2005;3():8.
2005: Gunther Meinlschmidt; Christine Heim
Decreased cortisol awakening response after early loss experience.
Psychoneuroendocrinology 2005;30(6):568-76.
2005: J Douglas Bremner; Tanja C Mletzko; Silke Welter; Sinead Quinn; Chanda Williams; Marijn E Brummer; Sajid Siddiq; Lai Reed; Christine Heim; Charles Nemeroff
Effects of phenytoin on memory, cognition and brain structure in post-traumatic stress disorder: a pilot study.
Journal of psychopharmacology (Oxford, England) 2005;19(2):159-65.
2005: William C Reeves; Dieter Wagner; Rosane Nisenbaum; James F Jones; Brian Gurbaxani; Laura Solomon; Dimitris A Papanicolaou; Elizabeth R Unger; Suzanne D Vernon; Christine Heim
Chronic fatigue syndrome--a clinically empirical approach to its definition and study.
BMC medicine 2005;3():19.
2004: J Douglas Bremner; Tanja C Mletzko; Silke Welter; Sajid Siddiq; Lai Reed; Chanda Williams; Christine Heim; Charles Nemeroff
Treatment of posttraumatic stress disorder with phenytoin: an open-label pilot study.
The Journal of clinical psychiatry 2004;65(11):1559-64.
2004: Christine Heim; Cynthia Bierl; Rosane Nisenbaum; Dieter Wagner; William C Reeves
Regional prevalence of fatiguing illnesses in the United States before and after the terrorist attacks of September 11, 2001.
Psychosomatic medicine 2004;66(5):672-8.
2004: Christine Heim; Paul M Plotsky; Charles Nemeroff
Importance of studying the contributions of early adverse experience to neurobiological findings in depression.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(4):641-8.
2004: D Jeffrey Newport; Christine Heim; Robert Bonsall; Andrew H Miller; Charles Nemeroff
Pituitary-adrenal responses to standard and low-dose dexamethasone suppression tests in adult survivors of child abuse.
Biological psychiatry 2004;55(1):10-20.
2003: Charles Nemeroff; Christine Heim; Michael E Thase; Daniel N Klein; A John Rush; Alan F Schatzberg; Philip T Ninan; James P McCullough; Paul M Weiss; David L Dunner; Barbara O Rothbaum; Susan G Kornstein; Gabor I Keitner; Martin B Keller
Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):14293-6.
2003: D Jeffrey Newport; Christine Heim; Michael J Owens; James C Ritchie; Clayton H Ramsey; Robert Bonsall; Andrew H Miller; Charles Nemeroff
Cerebrospinal fluid corticotropin-releasing factor (CRF) and vasopressin concentrations predict pituitary response in the CRF stimulation test: a multiple regression analysis.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(3):569-76.
2002: Meena Vythilingam; Christine Heim; D Jeffrey Newport; Andrew H Miller; Eric Anderson; Richard A Bronen; Marijn Brummer; Lawrence H Staib; Eric Vermetten; Dennis S Charney; Charles Nemeroff; J Douglas Bremner
Childhood trauma associated with smaller hippocampal volume in women with major depression.
The American journal of psychiatry 2002;159(12):2072-80.
2002: Christine Heim; Charles Nemeroff
Neurobiology of early life stress: clinical studies.
Seminars in clinical neuropsychiatry 2002;7(2):147-59.
2002: Christine Heim; D Jeffrey Newport; Dieter Wagner; Molly M Wilcox; Andrew H Miller; Charles Nemeroff
The role of early adverse experience and adulthood stress in the prediction of neuroendocrine stress reactivity in women: a multiple regression analysis.
Depression and anxiety 2002;15(3):117-25.
2001: Christine Heim; Charles Nemeroff
The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies.
Biological psychiatry 2001;49(12):1023-39.
2001: Christine Heim; D Jeffrey Newport; Robert Bonsall; Andrew H Miller; Charles Nemeroff
Altered pituitary-adrenal axis responses to provocative challenge tests in adult survivors of childhood abuse.
The American journal of psychiatry 2001;158(4):575-81.
2000: Christine Heim; D Jeffrey Newport; S Heit; YP Graham; M Wilcox; Robert Bonsall; Andrew H Miller; Charles Nemeroff
Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood.
JAMA : the journal of the American Medical Association 2000;284(5):592-7.
2000: Christine Heim; Ulrike Ehlert; Dirk H Hellhammer
The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders.
Psychoneuroendocrinology 2000;25(1):1-35.
1999: Christine Heim; Charles Nemeroff
The impact of early adverse experiences on brain systems involved in the pathophysiology of anxiety and affective disorders.
Biological psychiatry 1999;46(11):1509-22.
1999: Christine Heim; Ulrike Ehlert; Jürgen Hanker; Dirk H Hellhammer
Psychological and endocrine correlates of chronic pelvic pain associated with adhesions.
Journal of psychosomatic obstetrics and gynaecology 1999;20(1):11-20.
1999: Ulrike Ehlert; Christine Heim; Dirk H Hellhammer
Chronic pelvic pain as a somatoform disorder.
Psychotherapy and psychosomatics 1999;68(2):87-94.
1999: YP Graham; Christine Heim; Sherryl H Goodman; Andrew H Miller; Charles Nemeroff
The effects of neonatal stress on brain development: implications for psychopathology.
Development and psychopathology 1999;11(3):545-65.
1998: Christine Heim; Ulrike Ehlert; Jürgen Hanker; Dirk H Hellhammer
Abuse-related posttraumatic stress disorder and alterations of the hypothalamic-pituitary-adrenal axis in women with chronic pelvic pain.
Psychosomatic medicine 1998;60(3):309-18.
1997: Christine Heim; Ulrike Ehlert; J Rexhausen; Jürgen Hanker; Dirk H Hellhammer
Psychoendocrinological observations in women with chronic pelvic pain.
Annals of the New York Academy of Sciences 1997;821():456-8.
1997: Christine Heim; Michael J Owens; Paul M Plotsky; Charles Nemeroff
The role of early adverse life events in the etiology of depression and posttraumatic stress disorder. Focus on corticotropin-releasing factor.
Annals of the New York Academy of Sciences 1997;821():194-207.
1997: Christine Heim; Michael J Owens; Paul M Plotsky; Charles Nemeroff
Persistent changes in corticotropin-releasing factor systems due to early life stress: relationship to the pathophysiology of major depression and post-traumatic stress disorder.
Psychopharmacology bulletin 1997;33(2):185-92.