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Claude Lazure

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Genes & Molecular Sequences

Amino Acid Sequences

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Maxime Denis; Dany Gauthier; Claude Lazure; Jadwiga Marcinkiewicz; Steve Poirier; Nabil G Seidah; Ahmed Zaid; Annik Prat
Gene inactivation of proprotein convertase subtilisin/kexin type 9 reduces atherosclerosis in mice.
Florian Heyd; Riyan Chen; Khashayar Afshar; Ingrid Saba; Claude Lazure; Katharina Fiolka; Tarik Möröy
The p150 subunit of the histone chaperone Caf-1 interacts with the transcriptional repressor Gfi1.
Anna Roubtsova; Mercedes Nancy Munkonda; Zuhier Awan; Jadwiga Marcinkiewicz; Ann Chamberland; Claude Lazure; Katherine Cianflone; Nabil G Seidah; Annik Prat
Circulating proprotein convertase subtilisin/kexin 9 (PCSK9) regulates VLDLR protein and triglyceride accumulation in visceral adipose tissue.

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All Publications

2012: Maxime Denis; Dany Gauthier; Claude Lazure; Jadwiga Marcinkiewicz; Steve Poirier; Nabil G Seidah; Ahmed Zaid; Annik Prat
Gene inactivation of proprotein convertase subtilisin/kexin type 9 reduces atherosclerosis in mice.
Circulation 2012;125(7):894-901.
2011: Florian Heyd; Riyan Chen; Khashayar Afshar; Ingrid Saba; Claude Lazure; Katharina Fiolka; Tarik Möröy
The p150 subunit of the histone chaperone Caf-1 interacts with the transcriptional repressor Gfi1.
Biochimica et biophysica acta 2011;1809(4-6):255-61.
2011: Anna Roubtsova; Mercedes Nancy Munkonda; Zuhier Awan; Jadwiga Marcinkiewicz; Ann Chamberland; Claude Lazure; Katherine Cianflone; Nabil G Seidah; Annik Prat
Circulating proprotein convertase subtilisin/kexin 9 (PCSK9) regulates VLDLR protein and triglyceride accumulation in visceral adipose tissue.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(4):785-91.
2008: Daniel J Gauthier; Jacqueline A Sobota; Francesco Ferraro; Richard E Mains; Claude Lazure
Flow cytometry-assisted purification and proteomic analysis of the corticotropes dense-core secretory granules.
Proteomics 2008;8(18):3848-61.
2008: Daniel J Gauthier; Claude Lazure
Complementary methods to assist subcellular fractionation in organellar proteomics.
Expert review of proteomics 2008;5(4):603-17.
2007: Ching Yin Lee; Taku Tamura; Nadia Rabah; Dong-Young Donna Lee; Isabelle L Ruel; Anouar Hafiane; Iulia Iatan; Dana Nyholt; Frédéric Laporte; Claude Lazure; Ikuo Wada; Larbi Krimbou; Jacques Genest
Carboxyl-terminal disulfide bond of acid sphingomyelinase is critical for its secretion and enzymatic function.
Biochemistry 2007;46(51):14969-78.
2007: Nadia Rabah; Dany Gauthier; Jimmy D Dikeakos; Timothy L Reudelhuber; Claude Lazure
The C-terminal region of the proprotein convertase 1/3 (PC1/3) exerts a bimodal regulation of the enzyme activity in vitro.
The FEBS journal 2007;274(13):3482-91.
2007: Marie-France Lusignan; Annick Bergeron; Marie-Hélène Crête; Claude Lazure; Puttaswamy Manjunath
Induction of epididymal boar sperm capacitation by pB1 and BSP-A1/-A2 proteins, members of the BSP protein family.
Biology of reproduction 2007;76(3):424-32.
2006: Nadia Rabah; Dany Gauthier; Brian C Wilkes; Daniel J Gauthier; Claude Lazure
Single amino acid substitution in the PC1/3 propeptide can induce significant modifications of its inhibitory profile toward its cognate enzyme.
The Journal of biological chemistry 2006;281(11):7556-67.
2005: Pierre D'Amour; Jean-Hugues Brossard; Louise Rousseau; Loan Nguyen-Yamamoto; Edgard Nassif; Claude Lazure; Dany Gauthier; Jeffrey R Lavigne; Richard J Zahradnik
Structure of non-(1-84) PTH fragments secreted by parathyroid glands in primary and secondary hyperparathyroidism.
Kidney international 2005;68(3):998-1007.
2005: Annick Bergeron; Michèle Villemure; Claude Lazure; Puttaswamy Manjunath
Isolation and characterization of the major proteins of ram seminal plasma.
Molecular reproduction and development 2005;71(4):461-70.
2004: Daniel J Gauthier; Bernard F Gibbs; Nadia Rabah; Claude Lazure
Utilization of a new biotinylation reagent in the development of a nondiscriminatory investigative approach for the study of cell surface proteins.
Proteomics 2004;4(12):3783-90.
2004: Nadia Rabah; Daniel J Gauthier; Dany Gauthier; Claude Lazure
Improved PC1/3 production through recombinant expression in insect cells and larvae.
Protein expression and purification 2004;37(2):377-84.
2004: Mélanie Boisvert; Annick Bergeron; Claude Lazure; Puttaswamy Manjunath
Isolation and characterization of gelatin-binding bison seminal vesicle secretory proteins.
Biology of reproduction 2004;70(3):656-61.
2003: Martin Ménard; Veronica Nauc; Claude Lazure; Denis Vaillancourt; Puttaswamy Manjunath
Novel purification method for mammalian seminal plasma phospholipid-binding proteins reveals the presence of a novel member of this family of protein in stallion seminal fluid.
Molecular reproduction and development 2003;66(4):349-57.
2003: Michèle Villemure; Alain Fournier; Dany Gauthier; Nadia Rabah; Brian C Wilkes; Claude Lazure
Barley serine proteinase inhibitor 2-derived cyclic peptides as potent and selective inhibitors of convertases PC1/3 and furin.
Biochemistry 2003;42(32):9659-68.
2003: Ajoy Basak; Claude Lazure
Synthetic peptides derived from the prosegments of proprotein convertase 1/3 and furin are potent inhibitors of both enzymes.
The Biochemical journal 2003;373(Pt 1):231-9.
2003: Michèle Villemure; Claude Lazure; Puttaswamy Manjunath
Isolation and characterization of gelatin-binding proteins from goat seminal plasma.
Reproductive biology and endocrinology : RB&E 2003;1():39.
2002: Claude Lazure
The peptidase zymogen proregions: nature's way of preventing undesired activation and proteolysis.
Current pharmaceutical design 2002;8(7):511-31.
2001: Claude Lazure; Michèle Villemure; Dany Gauthier; R J Naudé; Majambu Mbikay
Characterization of ostrich (Struthio camelus) beta-microseminoprotein (MSP): identification of homologous sequences in EST databases and analysis of their evolution during speciation.
Protein science : a publication of the Protein Society 2001;10(11):2207-18.
2001: Suzanne Benjannet; A Elagoz; Louise Wickham; M Mamarbachi; JS Munzer; Ajoy Basak; Claude Lazure; James A Cromlish; Sangram S Sisodia; F Checler; Michel Chrétien; Nabil G Seidah
Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production.
The Journal of biological chemistry 2001;276(14):10879-87.
2000: Jean-Bernard Denault; Claude Lazure; Robert Day; Richard Leduc
Comparative characterization of two forms of recombinant human SPC1 secreted from Schneider 2 cells.
Protein expression and purification 2000;19(1):113-24.
2000: BB Touré; JS Munzer; Ajoy Basak; Suzanne Benjannet; J Rochemont; Claude Lazure; Michel Chrétien; Nabil G Seidah
Biosynthesis and enzymatic characterization of human SKI-1/S1P and the processing of its inhibitory prosegment.
The Journal of biological chemistry 2000;275(4):2349-58.
1999: Ajoy Basak; BB Touré; Claude Lazure; Majambu Mbikay; Michel Chrétien; Nabil G Seidah
Enzymic characterization in vitro of recombinant proprotein convertase PC4.
The Biochemical journal 1999;343 Pt 1():29-37.
1999: Nabil G Seidah; SJ Mowla; Josée Hamelin; Aida M Mamarbachi; Suzanne Benjannet; BB Touré; Ajoy Basak; JS Munzer; Jadwiga Marcinkiewicz; M Zhong; J C Barale; Claude Lazure; Richard A Murphy; Michel Chrétien; Mieczyslaw Marcinkiewicz
Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1321-6.
1998: A Boudreault; Dany Gauthier; N Rondeau; D Savaria; Nabil G Seidah; Michel Chrétien; Claude Lazure
Molecular characterization, enzymatic analysis, and purification of murine proprotein convertase-1/3 (PC1/PC3) secreted from recombinant baculovirus-infected insect cells.
Protein expression and purification 1998;14(3):353-66.
1998: A Boudreault; Dany Gauthier; Claude Lazure
Proprotein convertase PC1/3-related peptides are potent slow tight-binding inhibitors of murine PC1/3 and Hfurin.
The Journal of biological chemistry 1998;273(47):31574-80.
1998: Gilles Frenette; Roland R Tremblay; JY Dubé; Claude Lazure; M Lemay
High concentrations of the macrophage migration inhibitory factor in human seminal plasma and prostatic tissues.
Archives of andrology 1998;41(3):185-93.
1998: K Johanning; Maria A Juliano; Luiz Juliano; Claude Lazure; NS Lamango; Donald F Steiner; Iris Lindberg
Specificity of prohormone convertase 2 on proenkephalin and proenkephalin-related substrates.
The Journal of biological chemistry 1998;273(35):22672-80.
1998: R Moreau; Isabelle Thérien; Claude Lazure; Puttaswamy Manjunath
Type II domains of BSP-A1/-A2 proteins: binding properties, lipid efflux, and sperm capacitation potential.
Biochemical and biophysical research communications 1998;246(1):148-54.
1998: Claude Lazure; Dany Gauthier; F Jean; A Boudreault; Nabil G Seidah; H P Bennett; G N Hendy
In vitro cleavage of internally quenched fluorogenic human proparathyroid hormone and proparathyroid-related peptide substrates by furin. Generation of a potent inhibitor.
The Journal of biological chemistry 1998;273(15):8572-80.
1998: Raymond Lepage; Louise Roy; Jean-Hugues Brossard; Louise Rousseau; C Dorais; Claude Lazure; Pierre D'Amour
A non-(1-84) circulating parathyroid hormone (PTH) fragment interferes significantly with intact PTH commercial assay measurements in uremic samples.
Clinical chemistry 1998;44(4):805-9.
1998: Robert Day; Claude Lazure; Ajoy Basak; A Boudreault; P Limperis; Weijia Dong; Iris Lindberg
Prodynorphin processing by proprotein convertase 2. Cleavage at single basic residues and enhanced processing in the presence of carboxypeptidase activity.
The Journal of biological chemistry 1998;273(2):829-36.
1998: S Soubeyrand; Claude Lazure; Puttaswamy Manjunath
Phospholipase A2 from bovine seminal plasma is a platelet-activating factor acetylhydrolase.
The Biochemical journal 1998;329 ( Pt 1)():41-7.
1997: D Deperthes; F Marceau; Gilles Frenette; Claude Lazure; Roland R Tremblay; JY Dubé
Human kallikrein hK2 has low kininogenase activity while prostate-specific antigen (hK3) has none.
Biochimica et biophysica acta 1997;1343(1):102-6.
1997: JS Munzer; Ajoy Basak; M Zhong; Aida M Mamarbachi; Josée Hamelin; D Savaria; Claude Lazure; G N Hendy; Suzanne Benjannet; Michel Chrétien; Nabil G Seidah
In vitro characterization of the novel proprotein convertase PC7.
The Journal of biological chemistry 1997;272(32):19672-81.
1997: Ajoy Basak; B Ernst; D Brewer; Nabil G Seidah; JS Munzer; Claude Lazure; Gilles Lajoie
Histidine-rich human salivary peptides are inhibitors of proprotein convertases furin and PC7 but act as substrates for PC1.
The journal of peptide research : official journal of the American Peptide Society 1997;49(6):596-603.
1997: Gilles Frenette; Roland R Tremblay; Claude Lazure; J Y Dube
Prostatic kallikrein hK2, but not prostate-specific antigen (hK3), activates single-chain urokinase-type plasminogen activator.
International journal of cancer. Journal international du cancer 1997;71(5):897-9.
1997: I Lemire; Claude Lazure; Philippe Crine; Guy Boileau
Secretion of a type II integral membrane protein induced by mutation of the transmembrane segment.
The Biochemical journal 1997;322 ( Pt 1)():335-42.
1997: Gilles Frenette; D Deperthes; Roland R Tremblay; Claude Lazure; JY Dubé
Purification of enzymatically active kallikrein hK2 from human seminal plasma.
Biochimica et biophysica acta 1997;1334(1):109-15.
1996: jeff Keyser; S Wouters; C Di Bello; Claude Lazure; Jean-Marie Ruysschaert; Nabil G Seidah
Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines.
The Journal of biological chemistry 1996;271(48):30442-50.
1996: M Zhong; Suzanne Benjannet; Claude Lazure; S Munzer; Nabil G Seidah
Functional analysis of human PACE4-A and PACE4-C isoforms: identification of a new PACE4-CS isoform.
FEBS letters 1996;396(1):31-6.
1996: Nabil G Seidah; Suzanne Benjannet; S Pareek; D Savaria; Josée Hamelin; B Goulet; J Laliberte; Claude Lazure; Michel Chrétien; R A Murphy
Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases.
The Biochemical journal 1996;314 ( Pt 3)():951-60.
1996: F Vollenweider; Suzanne Benjannet; jeff Keyser; D Savaria; Claude Lazure; Gary Thomas; Michel Chrétien; Nabil G Seidah
Comparative cellular processing of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 by the mammalian subtilisin/kexin-like convertases.
The Biochemical journal 1996;314 ( Pt 2)():521-32.
1995: D Deperthes; P Chapdelaine; Roland R Tremblay; C Brunet; J Berton; J Hébert; Claude Lazure; JY Dubé
Isolation of prostatic kallikrein hK2, also known as hGK-1, in human seminal plasma.
Biochimica et biophysica acta 1995;1245(3):311-6.
1995: Ajoy Basak; A Boudreault; A Chen; Michel Chrétien; Nabil G Seidah; Claude Lazure
Application of the multiple antigenic peptides (MAP) strategy to the production of prohormone convertases antibodies: synthesis, characterization and use of 8-branched immunogenic peptides.
Journal of peptide science : an official publication of the European Peptide Society 1995;1(6):385-95.
1995: Ajoy Basak; C Schmidt; A A Ismail; Nabil G Seidah; Michel Chrétien; Claude Lazure
Peptidyl substrates containing unnatural amino acid at the P'1 position are potent inhibitors of prohormone convertases.
International journal of peptide and protein research 1995;46(3-4):228-37.
1995: F Jean; A Boudreault; Ajoy Basak; Nabil G Seidah; Claude Lazure
Fluorescent peptidyl substrates as an aid in studying the substrate specificity of human prohormone convertase PC1 and human furin and designing a potent irreversible inhibitor.
The Journal of biological chemistry 1995;270(33):19225-31.
1995: F Jean; Ajoy Basak; J DiMaio; Nabil G Seidah; Claude Lazure
An internally quenched fluorogenic substrate of prohormone convertase 1 and furin leads to a potent prohormone convertase inhibitor.
The Biochemical journal 1995;307 ( Pt 3)():689-95.
1995: D Deperthes; Eric Gauthier; P Chapdelaine; Claude Lazure; Roland R Tremblay; JY Dubé
Identification of glandular kallikrein in dog pancreas and determination of its tissue distribution.
Biochimica et biophysica acta 1995;1243(3):291-4.
1995: I De Bie; D Savaria; A J Roebroek; R Day; Claude Lazure; W J Van de Ven; Nabil G Seidah
Processing specificity and biosynthesis of the Drosophila melanogaster convertases dfurin1, dfurin1-CRR, dfurin1-X, and dfurin2.
The Journal of biological chemistry 1995;270(3):1020-8.
1994: X F Yang; C Chatellard; Claude Lazure; Philippe Crine; Guy Boileau
Insertion of hydrophilic amino acid residues in the signal peptide/membrane anchor domain of neprilysin (neutral endopeptidase-24.11) results in its cleavage: role of the position of insertion.
Archives of biochemistry and biophysics 1994;315(2):382-6.
1994: Ajoy Basak; F Jean; Nabil G Seidah; Claude Lazure
Design and synthesis of novel inhibitors of prohormone convertases.
International journal of peptide and protein research 1994;44(3):253-61.
1994: L Paquet; F Bergeron; A Boudreault; Nabil G Seidah; Michel Chrétien; Majambu Mbikay; Claude Lazure
The neuroendocrine precursor 7B2 is a sulfated protein proteolytically processed by a ubiquitous furin-like convertase.
The Journal of biological chemistry 1994;269(30):19279-85.
1994: Ajoy Basak; F Jean; H Dugas; Claude Lazure
Biotinylation of an enkephalin-containing heptapeptide via various spacer arms. Synthesis, comparative binding studies toward avidin, and application as substrates in enzymatic reactions.
Bioconjugate chemistry 1994;5(4):301-5.
1994: A Dupuy; Iris Lindberg; Y Zhou; Huda Akil; Claude Lazure; Michel Chrétien; Nabil G Seidah; R Day
Processing of prodynorphin by the prohormone convertase PC1 results in high molecular weight intermediate forms. Cleavage at a single arginine residue.
FEBS letters 1994;337(1):60-5.
1993: P Chapdelaine; Claude Lazure; D Deperthes; Roland R Tremblay; J Y Dube
The major dog pancreas protein recognized by an antiserum to dog prostate kallikrein is the anionic trypsin.
The International journal of biochemistry 1993;25(12):1743-7.
1993: Suzanne Benjannet; N Rondeau; L Paquet; A Boudreault; Claude Lazure; Michel Chrétien; Nabil G Seidah
Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1 and PC2.
The Biochemical journal 1993;294 ( Pt 3)():735-43.
1993: F Jean; Ajoy Basak; N Rondeau; Suzanne Benjannet; Geoffrey N Hendy; Nabil G Seidah; Michel Chrétien; Claude Lazure
Enzymic characterization of murine and human prohormone convertase-1 (mPC1 and hPC1) expressed in mammalian GH4C1 cells.
The Biochemical journal 1993;292 ( Pt 3)():891-900.
1993: Ryno J Naudé; D Litthauer; Willem Oelofsen; Michel Chrétien; Claude Lazure
The production of the ostrich NH2-terminal POMC fragment requires cleavage at a unique signal peptidase site.
Peptides 1993;14(3):519-29.
1993: Ajoy Basak; A Boudreault; F Jean; Michel Chrétien; Claude Lazure
Radiolabeled biotinyl peptides as useful reagents for the study of proteolytic enzymes.
Analytical biochemistry 1993;209(2):306-14.
1991: L Paquet; N Rondeau; Nabil G Seidah; Claude Lazure; Michel Chrétien; Majambu Mbikay
Immunological identification and sequence characterization of a peptide derived from the processing of neuroendocrine protein 7B2.
FEBS letters 1991;294(1-2):23-6.
1991: Claude Lazure; Suzanne Benjannet; Nabil G Seidah; Michel Chrétien
Processed forms of neuroendocrine proteins 7B2 and secretogranin II are found in porcine pituitary extracts.
International journal of peptide and protein research 1991;38(4):392-400.
1991: A Ferreira; D Litthauer; H Saayman; Willem Oelofsen; J Crabb; Claude Lazure
Purification and primary structure of glucagon from ostrich pancreas splenic lobes.
International journal of peptide and protein research 1991;38(1):90-5.
1991: F Jean; Ajoy Basak; Michel Chrétien; Claude Lazure
Detection of endopeptidase activity and analysis of cleavage specificity using a radiometric solid-phase enzymatic assay.
Analytical biochemistry 1991;194(2):399-406.
1991: L Paquet; Claude Lazure; Nabil G Seidah; Michel Chrétien; Majambu Mbikay
The production by alternate splicing of two mRNAs differing by one codon could be an intrinsic property of neuroendocrine protein 7B2 gene expression in man.
Biochemical and biophysical research communications 1991;174(1):156-62.
1991: Nabil G Seidah; Mieczyslaw Marcinkiewicz; Suzanne Benjannet; L Gaspar; G Beaubien; M G Mattei; Claude Lazure; Majambu Mbikay; Michel Chrétien
Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.
Molecular endocrinology (Baltimore, Md.) 1991;5(1):111-22.
1991: M Chretien; L Gasper; Suzanne Benjannet; Majambu Mbikay; Claude Lazure; Nabil G Seidah
The Jeremiah Metzger Lecture. From POMC to functional diversity of neural peptides: the key importance of convertases.
Transactions of the American Clinical and Climatological Association 1991;102():195-224.
1990: Ajoy Basak; Y T Gong; J A Cromlish; J A Paquin; F Jean; Nabil G Seidah; Claude Lazure; Michel Chrétien
Syntheses of argininal semicarbazone containing peptides and their applications in the affinity chromatography of serine proteinases.
International journal of peptide and protein research 1990;36(1):7-17.
1990: Claude Lazure; L Paquet; D Litthauer; Ryno J Naudé; Willem Oelofsen; Michel Chrétien
The ostrich pituitary contains a major peptide homologous to mammalian chromogranin A(1-76).
Peptides 1990;11(1):79-87.
1989: J Paquin; Suzanne Benjannet; N Sawyer; Claude Lazure; Michel Chrétien; Nabil G Seidah
Rat plasma kallikrein: purification, NH2-terminal sequencing and development of a specific radioimmunoassay.
Biochimica et biophysica acta 1989;999(2):103-10.
1989: N G Seidah; R Ladenheim; Majambu Mbikay; Josée Hamelin; G Lutfalla; F Rougeon; Claude Lazure; Michel Chrétien
The cDNA structure of rat plasma kallikrein.
DNA (Mary Ann Liebert, Inc.) 1989;8(8):563-74.
1989: L Berthiaume; Danièle Beaudry; Claude Lazure; D R Tolan; Jurgen Sygusch
Recombinant anaerobic maize aldolase: overexpression, characterization, and metabolic implications.
Archives of biochemistry and biophysics 1989;272(2):281-9.
1989: Claude Lazure; H S Saayman; Ryno J Naudé; Willem Oelofsen; Michel Chrétien
Ostrich MSEL-neurophysin belongs to the class of two-domain "big" neurophysin as indicated by complete amino acid sequence of the neurophysin/copeptin.
International journal of peptide and protein research 1989;33(1):46-58.
1988: Mieczyslaw Marcinkiewicz; R Fischer-Colbrie; Jean-Pierre Falgueyret; Suzanne Benjannet; Nabil G Seidah; Claude Lazure; H Winkler; Michel Chrétien
Two-dimensional immunoblotting analysis and immunocytochemical localization of the secretory polypeptide 7B2 in adrenal medulla.
Neuroscience letters 1988;95(1-3):81-7.
1987: Suzanne Benjannet; R Leduc; N Adrouche; Jean-Pierre Falgueyret; Mieczyslaw Marcinkiewicz; Nabil G Seidah; Majambu Mbikay; Claude Lazure; M Chretien
Chromogranin B (secretogranin I), a putative precursor of two novel pituitary peptides through processing at paired basic residues.
FEBS letters 1987;224(1):142-8.
1987: Claude Lazure; H S Saayman; Ryno J Naudé; Willem Oelofsen; Michel Chrétien
Complete amino acid sequence of a VLDV-type neurophysin from ostrich differs markedly from known mammalian neurophysins.
International journal of peptide and protein research 1987;30(5):634-45.
1987: Nabil G Seidah; Geoffrey N Hendy; Josée Hamelin; J Paquin; Claude Lazure; K M Metters; J Rossier; Michel Chrétien
Chromogranin A can act as a reversible processing enzyme inhibitor. Evidence from the inhibition of the IRCM-serine protease 1 cleavage of pro-enkephalin and ACTH at pairs of basic amino acids.
FEBS letters 1987;211(2):144-50.
1985: Suzanne Benjannet; R Leduc; Claude Lazure; Nabil G Seidah; Mieczyslaw Marcinkiewicz; Michel Chrétien
GAWK, a novel human pituitary polypeptide: isolation, immunocytochemical localization and complete amino acid sequence.
Biochemical and biophysical research communications 1985;126(1):602-9.
1984: D Pélaprat; N G Seidah; R A Sikstrom; P Lambelin; Josée Hamelin; Claude Lazure; J A Cromlish; Michel Chrétien
Subcellular fractionation of pituitary neurointermediate lobes: revelation of various basic proteases.
Endocrinology 1984;115(2):581-90.
1983: Nabil G Seidah; D Pélaprat; J Rochemont; P Lambelin; M Dennis; J S Chan; Josée Hamelin; Claude Lazure; Michel Chrétien
Enzymatic maturation of pro-opiomelanocortin by anterior pituitary granules. Methodological approach leading to definite characterization of cleavage sites by means of high-performance liquid chromatography and microsequencing.
Journal of chromatography 1983;266():213-24.