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Thomas Schmidt

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Publications

TOP 3
Amal M M Nour; Sami A Khalid; Marcel Kaiser; Reto Brun; Wai'l E Abdallah; Thomas Schmidt
The antiprotozoal activity of sixteen asteraceae species native to Sudan and bioactivity-guided isolation of xanthanolides from Xanthium brasilicum.
ADELEKE ADEBAJO; Ezekiel O Iwalewa; Efere Obuotor; G F Ibikunle; N O A Omisore; Clement O Adewunmi; O O Obaparusi; M Klaes; G E Adetogun; Thomas Schmidt; Eugen J Verspohl
Pharmacological properties of the extract and some isolated compounds of Clausena lansium stem bark: anti-trichomonal, antidiabetic, anti-inflammatory, hepatoprotective and antioxidant effects.
Thomas Schmidt; Amal M M Nour; Sami A Khalid; Marcel Kaiser; Reto Brun
Quantitative structure--antiprotozoal activity relationships of sesquiterpene lactones.

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All Publications

2009: Amal M M Nour; Sami A Khalid; Marcel Kaiser; Reto Brun; Wai'l E Abdallah; Thomas Schmidt
The antiprotozoal activity of sixteen asteraceae species native to Sudan and bioactivity-guided isolation of xanthanolides from Xanthium brasilicum.
Planta medica 2009;75(12):1363-8.
2009: ADELEKE ADEBAJO; Ezekiel O Iwalewa; Efere Obuotor; G F Ibikunle; N O A Omisore; Clement O Adewunmi; O O Obaparusi; M Klaes; G E Adetogun; Thomas Schmidt; Eugen J Verspohl
Pharmacological properties of the extract and some isolated compounds of Clausena lansium stem bark: anti-trichomonal, antidiabetic, anti-inflammatory, hepatoprotective and antioxidant effects.
Journal of ethnopharmacology 2009;122(1):10-9.
2009: Thomas Schmidt; Amal M M Nour; Sami A Khalid; Marcel Kaiser; Reto Brun
Quantitative structure--antiprotozoal activity relationships of sesquiterpene lactones.
Molecules (Basel, Switzerland) 2009;14(6):2062-76.
2009: Martin Rostami-Yazdi; Bernd Clement; Thomas Schmidt; Daniel Schinor; Ulrich Mrowietz
Detection of metabolites of fumaric acid esters in human urine: implications for their mode of action.
The Journal of investigative dermatology 2009;129(1):231-4.
2008: Thomas Schmidt; A Wilhelm Alfermann; Elisabeth Fuss
High-performance liquid chromatography/mass spectrometric identification of dibenzylbutyrolactone-type lignans: insights into electrospray ionization tandem mass spectrometric fragmentation of lign-7-eno-9,9'-lactones and application to the lignans of Linum usitatissimum L. (Common Flax).
Rapid communications in mass spectrometry : RCM 2008;22(22):3642-50.
2008: Aynur Tasdemir; Farid Khan; Thomas A Jowitt; Lucia Iuzzolino; Stefan Lohmer; Sabrina Corazza; Thomas Schmidt
Engineering of a monomeric fluorescent protein AsGFP499 and its applications in a dual translocation and transcription assay.
Protein engineering, design & selection : PEDS 2008;21(10):613-22.
2008: Nikolay Vasilev; Rainer Ebel; RuAngelie Edrada-Ebel; Elisabeth Fuss; A Wilhelm Alfermann; Iliana Ionkova; Ana Petrova; Miriam Repplinger; Thomas Schmidt
Metabolic profiling of lignan variability in Linum species of section Syllinum native to Bulgaria.
Planta medica 2008;74(3):273-80.
2007: Matthias Lechtenberg; S Zumdick; C Gerhards; Thomas Schmidt; A Hensel
Evaluation of analytical markers characterising different drying methods of parsley leaves (Petroselinum crispum L.).
Die Pharmazie 2007;62(12):949-54.
2007: Thomas Schmidt; Sonja Vössing; M Klaes; Stefan Grimme
An aryldihydronaphthalene lignan with a novel type of ring system and further new lignans from linum perenne L.
Planta medica 2007;73(15):1574-80.
2007: Shiva Hemmati; Bernd Schneider; Thomas Schmidt; Katja Federolf; A Wilhelm Alfermann; Elisabeth Fuss
Justicidin B 7-hydroxylase, a cytochrome P450 monooxygenase from cell cultures of Linum perenne Himmelszelt involved in the biosynthesis of diphyllin.
Phytochemistry 2007;68(22-24):2736-43.
2007: ADELEKE ADEBAJO; E O Olawode; OR Omobuwajo; SA Adesanya; F Begrow; A Elkhawad; Moses A Akanmu; RuAngelie Edrada-Ebel; P Proksch; Thomas Schmidt; M Klaes; Eugen J Verspohl
Hypoglycaemic constituents of Stachytarpheta cayennensis leaf.
Planta medica 2007;73(3):241-50.
2007: Shiva Hemmati; Thomas Schmidt; Elisabeth Fuss
(+)-Pinoresinol/(-)-lariciresinol reductase from Linum perenne Himmelszelt involved in the biosynthesis of justicidin B.
FEBS letters 2007;581(4):603-10.
2007: Abdolali Mohagheghzadeh; Azra Gholami; Shiva Hemmati; Mohammad Reza Shams Ardakani; Thomas Schmidt; A Wilhelm Alfermann
Root cultures of linum species section Syllinum as rich sources of 6-methoxypodophyllotoxin.
Zeitschrift für Naturforschung. C, Journal of biosciences 2007;62(1-2):43-9.
2007: Belma Konuklugil; Iliana Ionkova; Nikolay Vasilev; Thomas Schmidt; J Windhövel; Elisabeth Fuss; A Wilhelm Alfermann
Lignans from Linum species of sections Syllinum and Linum.
Natural product research 2007;21(1):1-6.
2007: Thomas Schmidt; Muharrem Ak; Ulrich Mrowietz
Reactivity of dimethyl fumarate and methylhydrogen fumarate towards glutathione and N-acetyl-L-cysteine--preparation of S-substituted thiosuccinic acid esters.
Bioorganic & medicinal chemistry 2007;15(1):333-42.
2006: Abdolali Mohagheghzadeh; Thomas Schmidt; Urün Bayindir; Elisabeth Fuss; Iraj Mehregan; A Wilhelm Alfermann
Diarylbutyrolactone lignans from Linum corymbulosum in vitro cultures.
Planta medica 2006;72(12):1165-7.
2006: Thomas Schmidt; Shiva Hemmati; Elisabeth Fuss; A Wilhelm Alfermann
A combined HPLC-UV and HPLC-MS method for the identification of lignans and its application to the lignans of Linum usitatissimum L. and L. bienne Mill.
Phytochemical analysis : PCA 2006;17(5):299-311.
2006: Thomas Schmidt; Sabine Stausberg; Jeanette Von Raison; Matthias Berner; Günter Willuhn
Lignans from Arnica species.
Natural product research 2006;20(5):443-53.
2006: Deniz Tasdemir; Marcel Kaiser; Reto Brun; Vanessa Yardley; Thomas Schmidt; Fatma Tosun; Peter Rüedi
Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies.
Antimicrobial agents and chemotherapy 2006;50(4):1352-64.
2005: Cosima B I von Heimendahl; Katrin M Schäfer; Patrik C Eklund; Rainer Sjöholm; Thomas Schmidt; Elisabeth Fuss
Pinoresinol-lariciresinol reductases with different stereospecificity from Linum album and Linum usitatissimum.
Phytochemistry 2005;66(11):1254-63.
2005: Sabine van Miert; Stefaan Van Dyck; Thomas Schmidt; Reto Brun; Arnold Vlietinck; Guy Lemière; Luc Pieters
Antileishmanial activity, cytotoxicity and QSAR analysis of synthetic dihydrobenzofuran lignans and related benzofurans.
Bioorganic & medicinal chemistry 2005;13(3):661-9.
2004: Thomas Schmidt; Jeanette von Raison; Günter Willuhn
New triterpene esters from flowerheads of Arnica lonchophylla.
Planta medica 2004;70(10):967-77.
2004: Thomas Schmidt; Marion Gurrath; Yoshihisa Ozoe
Structure-activity relationships of seco-prezizaane and picrotoxane/picrodendrane terpenoids by Quasar receptor-surface modeling.
Bioorganic & medicinal chemistry 2004;12(15):4159-67.
2003: Thomas Schmidt; Meike R Hildebrand; Günter Willuhn
New dihydrobenzofurans and triterpenoids from roots of Microglossa pyrifolia.
Planta medica 2003;69(3):258-64.
2002: Thomas Schmidt; Reto Brun; Günter Willuhn; Sami Khalid
Anti-trypanosomal activity of helenalin and some structurally related sesquiterpene lactones.
Planta medica 2002;68(8):750-1.
2002: Tadahiko Kuriyama; Thomas Schmidt; Emi Okuyama; Yoshihisa Ozoe
Structure-activity relationships of seco-prezizaane terpenoids in gamma-aminobutyric acid receptors of houseflies and rats.
Bioorganic & medicinal chemistry 2002;10(6):1873-81.
2002: Abdolali Mohagheghzadeh; Thomas Schmidt; A Wilhelm Alfermann
Arylnaphthalene lignans from in vitro cultures of Linum austriacum.
Journal of natural products 2002;65(1):69-71.
2001: Belma Konuklugil; Thomas Schmidt; A Wilhelm Alfermann
Accumulation of lignans in suspension cultures of Linum mucronatum ssp. armenum (Bordz.) Davis.
Zeitschrift für Naturforschung. C, Journal of biosciences 2001;56(11-12):1164-5.
2001: Alfonso J García-Piñeres; Victor Castro; G Mora; Thomas Schmidt; Elisabeth Strunck; Heike L Pahl; Irmgard Merfort
Cysteine 38 in p65/NF-kappaB plays a crucial role in DNA binding inhibition by sesquiterpene lactones.
The Journal of biological chemistry 2001;276(43):39713-20.
2001: Susanne Tornhamre; Thomas Schmidt; Barbro Näsman-Glaser; I Ericsson
Inhibitory effects of helenalin and related compounds on 5-lipoxygenase and leukotriene C(4) synthase in human blood cells.
Biochemical pharmacology 2001;62(7):903-11.
2001: J Heilmann; M R Wasescha; Thomas Schmidt
The influence of glutathione and cysteine levels on the cytotoxicity of helenanolide type sesquiterpene lactones against KB cells.
Bioorganic & medicinal chemistry 2001;9(8):2189-94.
2001: Thomas Schmidt; E Müller; F R Fronczek
New allo-cedrane type sesquiterpene hemiketals and further sesquiterpene lactones from fruits of Illicium floridanum.
Journal of natural products 2001;64(4):411-4.
2000: Thomas Schmidt; J Heilmann
Tetrahydrofuran lignans from Illicium floridanum and their activity in a luminol enhanced chemiluminescence assay.
Planta medica 2000;66(8):749-51.
2000: Thomas Schmidt; U Matthiesen; Günter Willuhn
On the stability of sesquiterpene lactones in the officinal Arnica tincture of the German pharmacopoeia.
Planta medica 2000;66(7):678-81.
2000: Thomas Schmidt
Glutathione adducts of helenalin and 11 alpha,13-dihydrohelenalin acetate inhibit glutathione S-transferase from horse liver.
Planta medica 2000;66(2):106-9.
1999: Thomas Schmidt; Emi Okuyama; F R Fronczek
The molecular structure of 2alpha-hydroxyneoanisatin and structure-activity relationships among convulsant sesquiterpenes of the seco-prezizaane and picrotoxane types.
Bioorganic & medicinal chemistry 1999;7(12):2857-65.
1999: Thomas Schmidt; G Lyss; Heike L Pahl; Irmgard Merfort
Helenanolide type sesquiterpene lactones. Part 5: the role of glutathione addition under physiological conditions.
Bioorganic & medicinal chemistry 1999;7(12):2849-55.
1999: Peter Rüngeler; Victor Castro; G Mora; N Gören; Walter Vichnewski; Heike L Pahl; Irmgard Merfort; Thomas Schmidt
Inhibition of transcription factor NF-kappaB by sesquiterpene lactones: a proposed molecular mechanism of action.
Bioorganic & medicinal chemistry 1999;7(11):2343-52.
1999: Belma Konuklugil; Thomas Schmidt; A Wilhelm Alfermann
Accumulation of aryltetralin lactone lignans in cell suspension cultures of Linum nodiflorum.
Planta medica 1999;65(6):587-8.
1998: G Lyss; A Knorre; Thomas Schmidt; Heike L Pahl; Irmgard Merfort
The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kappaB by directly targeting p65.
The Journal of biological chemistry 1998;273(50):33508-16.
1998: Günter Willuhn; A Skibinski; Thomas Schmidt
Structure revision of xanthalongin and further sesquiterpene lactones from flowers of Arnica longifolia.
Planta medica 1998;64(7):635-9.
1998: Thomas Schmidt; U Bomme; A Wilhelm Alfermann
Sesquiterpene lactone content in leaves of in vitro and field cultivated Arnica montana.
Planta medica 1998;64(3):268-70.
1997: G Lyss; Thomas Schmidt; Irmgard Merfort; Heike L Pahl
Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-kappaB.
Biological chemistry 1997;378(9):951-61.
1997: Thomas Schmidt
Helenanolide-type sesquiterpene lactones--III. Rates and stereochemistry in the reaction of helenalin and related helenanolides with sulfhydryl containing biomolecules.
Bioorganic & medicinal chemistry 1997;5(4):645-53.
1997: Aäron C Beekman; Herman J Woerdenbag; W van Uden; Niesko Pras; Antonius W T Konings; HV Wikström; Thomas Schmidt
Structure-cytotoxicity relationships of some helenanolide-type sesquiterpene lactones.
Journal of natural products 1997;60(3):252-7.
1995: Thomas Schmidt; G Willuhn; A Steigel; D Wendisch
Sesquiterpene lactones and inositol esters from Arnica angustifolia.
Planta medica 1995;61(6):544-50.
1994: Herman J Woerdenbag; Irmgard Merfort; Claus M Passreiter; Thomas Schmidt; G Willuhn; W van Uden; Niesko Pras; Harm H Kampinga; Antonius W T Konings
Cytotoxicity of flavonoids and sesquiterpene lactones from Arnica species against the GLC4 and the COLO 320 cell lines.
Planta medica 1994;60(5):434-7.