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Thomas Schmidt
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11
Alfermann, Wilhelm
7
Fuss, Elisabeth
6
Merfort, Irmgard
6
Willuhn, Günter
5
Pahl, Heike
4
Hemmati, Shiva
3
Konuklugil, Belma
3
Mohagheghzadeh, Abdolali
3
Lyss, G
2
Konings, Antonius
2
Okuyama, Emi
2
Mora, G
2
Pras, Niesko
2
Ionkova, Iliana
2
Castro, Victor
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All Publications
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2008: Schmidt Thomas J; Alfermann A Wilhelm; Fuss Elisabeth
High-performance liquid chromatography/mass spectrometric identification of dibenzylbutyrolactone-type lignans: insights into electrospray ionization tandem mass spectrometric fragmentation of lign-7-eno-9,9'-lactones and application to the lignans of Linum usitatissimum L. (Common Flax).
Rapid communications in mass spectrometry : RCM 2008;22(22):3642-50.
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2008: Tasdemir Aynur; Khan Farid; Jowitt Thomas A; Iuzzolino Lucia; Lohmer Stefan; Corazza Sabrina; Schmidt Thomas J
Engineering of a monomeric fluorescent protein AsGFP499 and its applications in a dual translocation and transcription assay.
Protein engineering, design & selection : PEDS 2008;21(10):613-22.
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2008: Vasilev Nikolay; Ebel Rainer; Edrada Ruangelie; Fuss Elisabeth; Alfermann A Wilhelm; Ionkova Iliana; Petrova Ana; Repplinger Miriam; Schmidt Thomas J
Metabolic profiling of lignan variability in Linum species of section Syllinum native to Bulgaria.
Planta medica 2008;74(3):273-80.
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2007: Lechtenberg M; Zumdick S; Gerhards C; Schmidt T J; Hensel A
Evaluation of analytical markers characterising different drying methods of parsley leaves (Petroselinum crispum L.).
Die Pharmazie 2007;62(12):949-54.
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2007: Schmidt Thomas J; Vössing Sonja; Klaes M; Grimme Stefan
An aryldihydronaphthalene lignan with a novel type of ring system and further new lignans from linum perenne L.
Planta medica 2007;73(15):1574-80.
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2007: Hemmati Shiva; Schneider Bernd; Schmidt Thomas J; Federolf Katja; Alfermann A Wilhelm; Fuss Elisabeth
Justicidin B 7-hydroxylase, a cytochrome P450 monooxygenase from cell cultures of Linum perenne Himmelszelt involved in the biosynthesis of diphyllin.
Phytochemistry 2007;68(22-24):2736-43.
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2007: Adebajo A C; Olawode E O; Omobuwajo O R; Adesanya S A; Begrow F; Elkhawad A; Akanmu M A; Edrada R; Proksch P; Schmidt T J; Klaes M; Verspohl E J
Hypoglycaemic constituents of Stachytarpheta cayennensis leaf.
Planta medica 2007;73(3):241-50.
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2007: Hemmati Shiva; Schmidt Thomas J; Fuss Elisabeth
(+)-Pinoresinol/(-)-lariciresinol reductase from Linum perenne Himmelszelt involved in the biosynthesis of justicidin B.
FEBS letters 2007;581(4):603-10.
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2007: Mohagheghzadeh Abdolali; Gholami Azra; Hemmati Shiva; Ardakani Mohammad Reza Shams; Schmidt Thomas J; Alfermann A Wilhelm
Root cultures of linum species section Syllinum as rich sources of 6-methoxypodophyllotoxin.
Zeitschrift für Naturforschung. C, Journal of biosciences 2007;62(1-2):43-9.
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2007: Konuklugil B; Ionkova I; Vasilev N; Schmidt T J; Windhövel J; Fuss E; Alfermann A W
Lignans from Linum species of sections Syllinum and Linum.
Natural product research 2007;21(1):1-6.
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2007: Schmidt Thomas J; Ak Muharrem; Mrowietz Ulrich
Reactivity of dimethyl fumarate and methylhydrogen fumarate towards glutathione and N-acetyl-L-cysteine--preparation of S-substituted thiosuccinic acid esters.
Bioorganic & medicinal chemistry 2007;15(1):333-42.
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2006: Mohagheghzadeh Abdolali; Schmidt Thomas J; Bayindir Urün; Fuss Elisabeth; Mehregan Iraj; Alfermann A Wilhelm
Diarylbutyrolactone lignans from Linum corymbulosum in vitro cultures.
Planta medica 2006;72(12):1165-7.
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2006: Schmidt Thomas J; Hemmati Shiva; Fuss Elisabeth; Alfermann A Wilhelm
A combined HPLC-UV and HPLC-MS method for the identification of lignans and its application to the lignans of Linum usitatissimum L. and L. bienne Mill.
Phytochemical analysis : PCA 2006;17(5):299-311.
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2006: Schmidt Thomas J; Stausberg Sabine; Raison Jeanette Von; Berner Matthias; Willuhn Günter
Lignans from Arnica species.
Natural product research 2006;20(5):443-53.
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2006: Tasdemir Deniz; Kaiser Marcel; Brun Reto; Yardley Vanessa; Schmidt Thomas J; Tosun Fatma; Rüedi Peter
Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies.
Antimicrobial agents and chemotherapy 2006;50(4):1352-64.
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2005: von Heimendahl Cosima B I; Schäfer Katrin M; Eklund Patrik; Sjöholm Rainer; Schmidt Thomas J; Fuss Elisabeth
Pinoresinol-lariciresinol reductases with different stereospecificity from Linum album and Linum usitatissimum.
Phytochemistry 2005;66(11):1254-63.
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2005: Van Miert Sabine; Van Dyck Stefaan; Schmidt Thomas J; Brun Reto; Vlietinck Arnold; Lemière Guy; Pieters Luc
Antileishmanial activity, cytotoxicity and QSAR analysis of synthetic dihydrobenzofuran lignans and related benzofurans.
Bioorganic & medicinal chemistry 2005;13(3):661-9.
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2004: Schmidt Thomas J; von Raison Jeanette; Willuhn Günter
New triterpene esters from flowerheads of Arnica lonchophylla.
Planta medica 2004;70(10):967-77.
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2004: Schmidt Thomas J; Gurrath Marion; Ozoe Yoshihisa
Structure-activity relationships of seco-prezizaane and picrotoxane/picrodendrane terpenoids by Quasar receptor-surface modeling.
Bioorganic & medicinal chemistry 2004;12(15):4159-67.
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2003: Schmidt Thomas J; Hildebrand Meike R; Willuhn Günter
New dihydrobenzofurans and triterpenoids from roots of Microglossa pyrifolia.
Planta medica 2003;69(3):258-64.
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2002: Schmidt Thomas J; Brun Reto; Willuhn Günter; Khalid Sami A
Anti-trypanosomal activity of helenalin and some structurally related sesquiterpene lactones.
Planta medica 2002;68(8):750-1.
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2002: Kuriyama Tadahiko; Schmidt Thomas J; Okuyama Emi; Ozoe Yoshihisa
Structure-activity relationships of seco-prezizaane terpenoids in gamma-aminobutyric acid receptors of houseflies and rats.
Bioorganic & medicinal chemistry 2002;10(6):1873-81.
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2002: Mohagheghzadeh Abdolali; Schmidt Thomas J; Alfermann A Wilhelm
Arylnaphthalene lignans from in vitro cultures of Linum austriacum.
Journal of natural products 2002;65(1):69-71.
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2001: Konuklugil B; Schmidt T J; Alfermann A W
Accumulation of lignans in suspension cultures of Linum mucronatum ssp. armenum (Bordz.) Davis.
Zeitschrift für Naturforschung. C, Journal of biosciences 2001;56(11-12):1164-5.
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2001: Tornhamre S; Schmidt T J; Näsman-Glaser B; Ericsson I; Lindgren JA
Inhibitory effects of helenalin and related compounds on 5-lipoxygenase and leukotriene C(4) synthase in human blood cells.
Biochemical pharmacology 2001;62(7):903-11.
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2001: García-Piñeres A J; Castro V; Mora G; Schmidt T J; Strunck E; Pahl H L; Merfort I
Cysteine 38 in p65/NF-kappaB plays a crucial role in DNA binding inhibition by sesquiterpene lactones.
The Journal of biological chemistry 2001;276(43):39713-20.
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2001: Heilmann J; Wasescha M R; Schmidt T J
The influence of glutathione and cysteine levels on the cytotoxicity of helenanolide type sesquiterpene lactones against KB cells.
Bioorganic & medicinal chemistry 2001;9(8):2189-94.
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2001: Schmidt T J; Müller E; Fronczek F R
New allo-cedrane type sesquiterpene hemiketals and further sesquiterpene lactones from fruits of Illicium floridanum.
Journal of natural products 2001;64(4):411-4.
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2000: Schmidt T J; Heilmann J
Tetrahydrofuran lignans from Illicium floridanum and their activity in a luminol enhanced chemiluminescence assay.
Planta medica 2000;66(8):749-51.
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2000: Schmidt T J; Matthiesen U; Willuhn G
On the stability of sesquiterpene lactones in the officinal Arnica tincture of the German pharmacopoeia.
Planta medica 2000;66(7):678-81.
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2000: Schmidt T J
Glutathione adducts of helenalin and 11 alpha,13-dihydrohelenalin acetate inhibit glutathione S-transferase from horse liver.
Planta medica 2000;66(2):106-9.
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1999: Schmidt T J; Okuyama E; Fronczek F R
The molecular structure of 2alpha-hydroxyneoanisatin and structure-activity relationships among convulsant sesquiterpenes of the seco-prezizaane and picrotoxane types.
Bioorganic & medicinal chemistry 1999;7(12):2857-65.
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1999: Schmidt T J; Lyss G; Pahl H L; Merfort I
Helenanolide type sesquiterpene lactones. Part 5: the role of glutathione addition under physiological conditions.
Bioorganic & medicinal chemistry 1999;7(12):2849-55.
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1999: Rüngeler P; Castro V; Mora G; Gören N; Vichnewski W; Pahl H L; Merfort I; Schmidt T J
Inhibition of transcription factor NF-kappaB by sesquiterpene lactones: a proposed molecular mechanism of action.
Bioorganic & medicinal chemistry 1999;7(11):2343-52.
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1999: Konuklugil B; Schmidt T J; Alfermann A W
Accumulation of aryltetralin lactone lignans in cell suspension cultures of Linum nodiflorum.
Planta medica 1999;65(6):587-8.
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1998: Lyss G; Knorre A; Schmidt T J; Pahl H L; Merfort I
The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kappaB by directly targeting p65.
The Journal of biological chemistry 1998;273(50):33508-16.
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1998: Willuhn G; Skibinski A; Schmidt T J
Structure revision of xanthalongin and further sesquiterpene lactones from flowers of Arnica longifolia.
Planta medica 1998;64(7):635-9.
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1998: Schmidt T J; Bomme U; Alfermann A W
Sesquiterpene lactone content in leaves of in vitro and field cultivated Arnica montana.
Planta medica 1998;64(3):268-70.
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1997: Lyss G; Schmidt T J; Merfort I; Pahl H L
Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-kappaB.
Biological chemistry 1997;378(9):951-61.
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1997: Schmidt T J
Helenanolide-type sesquiterpene lactones--III. Rates and stereochemistry in the reaction of helenalin and related helenanolides with sulfhydryl containing biomolecules.
Bioorganic & medicinal chemistry 1997;5(4):645-53.
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1997: Beekman A C; Woerdenbag H J; van Uden W; Pras N; Konings A W; Wikström H V; Schmidt T J
Structure-cytotoxicity relationships of some helenanolide-type sesquiterpene lactones.
Journal of natural products 1997;60(3):252-7.
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1995: Schmidt T J; Willuhn G; Steigel A; Wendisch D
Sesquiterpene lactones and inositol esters from Arnica angustifolia.
Planta medica 1995;61(6):544-50.
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1994: Woerdenbag H J; Merfort I; Passreiter C M; Schmidt T J; Willuhn G; van Uden W; Pras N; Kampinga H H; Konings A W
Cytotoxicity of flavonoids and sesquiterpene lactones from Arnica species against the GLC4 and the COLO 320 cell lines.
Planta medica 1994;60(5):434-7.
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