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Zhiyong Qian

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Lei Liu; Xuelei Ma; Zhiyong Qian; Qinjie Wu; Dake Xiong; Xia Zhao; Changyang Gong; Yuquan Wei
Camptothecine encapsulated composite drug delivery system for colorectal peritoneal carcinomatosis therapy: biodegradable microsphere in thermosensitive hydrogel.
Cheng Wang; Yujun Wang; Chengshi Xie; Lan Zhang; Xiaoxin Chen; Bingyang Chu; Chaofeng Long; Feng Luo; Zhiyong Qian
Two novel nanoscale preparations of micelle and thermosensitive hydrogel for docetaxel to treat malignant tumor.
Lei Liu; Zhiyong Qian; Lu Sun; YiShan Chen; Changyang Gong; Wenhao Guo; Ling Li; Yuchen Li; Qinjie Wu; Yuquan Wei
Curcumin loaded polymeric micelles inhibit breast tumor growth and spontaneous pulmonary metastasis.

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2013: Lei Liu; Xuelei Ma; Zhiyong Qian; Qinjie Wu; Dake Xiong; Xia Zhao; Changyang Gong; Yuquan Wei
Camptothecine encapsulated composite drug delivery system for colorectal peritoneal carcinomatosis therapy: biodegradable microsphere in thermosensitive hydrogel.
Colloids and surfaces. B, Biointerfaces 2013;106():93-101.
2013: Cheng Wang; Yujun Wang; Chengshi Xie; Lan Zhang; Xiaoxin Chen; Bingyang Chu; Chaofeng Long; Feng Luo; Zhiyong Qian
Two novel nanoscale preparations of micelle and thermosensitive hydrogel for docetaxel to treat malignant tumor.
Journal of biomedical nanotechnology 2013;9(3):357-66.
2013: Lei Liu; Zhiyong Qian; Lu Sun; YiShan Chen; Changyang Gong; Wenhao Guo; Ling Li; Yuchen Li; Qinjie Wu; Yuquan Wei
Curcumin loaded polymeric micelles inhibit breast tumor growth and spontaneous pulmonary metastasis.
International journal of pharmaceutics 2013;443(1-2):175-82.
2013: Yingjing Wang; Xi Yan; Feng Luo; Cheng Wang; Yujun Wang; Zhiyong Qian
Micelles of methoxy poly(ethylene glycol)-poly(epsilon-caprolactone) as a novel drug delivery vehicle for tacrolimus.
Journal of biomedical nanotechnology 2013;9(2):147-57.
2013: Zhiyong Qian; Shao-Zhi Fu; Si-Shen Feng
Nanohydrogels as a prospective member of the nanomedicine family.
Nanomedicine (London, England) 2013;8(2):161-4.
2013: DeXia Li; Jian Liang; Feng Luo; Xin Deng; RangRang Fan; Gang Guo; Zhiyong Qian
PLA/F68/dexamethasone implants prepared by hot-melt extrusion for controlled release of anti-inflammatory drug to implantable medical devices: I. Preparation, characterization and hydrolytic degradation study.
International journal of pharmaceutics 2013;441(1-2):365-72.
2013: Cheng Wang; Yingjing Wang; Yujun Wang; Chengshi Xie; Lan Zhang; Xiaoxin Chen; Xin Deng; Qingfa Guo; Jian Liang; Chaofeng Long; Feng Luo; Zhiyong Qian
Synthesis, characterization, and application of amino-terminated poly(ethylene glycol)-block-poly(epsilon-caprolactone) copolymer for paclitaxel.
Journal of nanoscience and nanotechnology 2013;13(1):68-76.
2013: Xiang Gao; Maling Gou; Meijuan Huang; Ning Huang; Xingyu Liu; Ke Men; Zhiyong Qian; Wang Rao; BiLan Wang; XiaWei Wei; Bowen Yang; Fen Zhao; Fang Ai; Yuquan Wei
Preparation, characterization and application of star-shaped PCL/PEG micelles for the delivery of doxorubicin in the treatment of colon cancer.
International journal of nanomedicine 2013;8():971-82.
2013: Changyang Gong; Ling Li; Yuchen Li; Lei Liu; Zhiyong Qian; Lu Sun; Bilan Wang; Xiawei Wei; Yishan Chen; Senyi Deng; Xiang Gao; Qinjie Wu; Mingli Xiang; Yuquan Wei
Improving antiangiogenesis and anti-tumor activity of curcumin by biodegradable polymeric micelles.
Biomaterials 2013;34(4):1413-32.
2012: Zichao Luo; Zhiyong Qian; Huashan Shi; Ping Sun; Dongmei Zhang; Hailong Zhang; Jing Zhang; Yuwei Zhao; Fuchun Guo; Meng Li; Shan Luo; Li Yang
Plasmid DNA containing multiple CpG motifs triggers a strong immune response to hepatitis B surface antigen when combined with incomplete Freund's adjuvant but not aluminum hydroxide.
Molecular medicine reports 2012;6(6):1309-14.
2012: Xiang Gao; MaLing Gou; Gang Guo; Meijuan Huang; Ning Huang; Ke Men; Zhiyong Qian; BiLan Wang; XiaWei Wei; Fengjin Zheng; Yu Zheng; Yingfeng Zhou; Yuquan Wei
Anticancer effect and mechanism of polymer micelle-encapsulated quercetin on ovarian cancer.
Nanoscale 2012;4(22):7021-30.
2012: ShaoZhi Fu; Feng Luo; PeiYan Ni; JinRong Peng; BeiYu Wang; Yuquan Wei; Xia Zhao; Lan Zheng; BingYang Chu; Zhiyong Qian
In vivo biocompatibility and osteogenesis of electrospun poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone)/nano-hydroxyapatite composite scaffold.
Biomaterials 2012;33(33):8363-71.
2012: Ke Men; Zhiyong Qian; BiLan Wang; Pan Wang; XiaWei Wei; Lijuan Chen; Yanan Du; XingMei Duan; Xiang Gao; MaLing Gou; MeiJuan Huang; Lin Li; Wei Liu; Yuquan Wei
Delivering instilled hydrophobic drug to the bladder by a cationic nanoparticle and thermo-sensitive hydrogel composite system.
Nanoscale 2012;4(20):6425-33.
2012: Ming Wu; Xianzheng Zhang; Yuanfang Zhang; Yiping Cao; Yong Chen; Liu He; Zhiyong Qian
Double "plug and play" templates technology for photo controllable drug release polyelectrolyte multilayers.
Chemical communications (Cambridge, England) 2012;48(79):9846-8.
2012: Changyang Gong; Lei Liu; Zhiyong Qian; Yujun Wang; Qinjie Wu; Mingli Xiang; Yongmei Xie; Dake Xiong; Senyi Deng; Yuquan Wei
Improving anti-tumor activity with polymeric micelles entrapping paclitaxel in pulmonary carcinoma.
Nanoscale 2012;4(19):6004-17.
2012: Na Lei; Feng Luo; Zhiyong Qian; Cheng Wang; HeLan Wang; ChangYang Gong; Yuquan Wei
Therapeutic application of injectable thermosensitive hydrogel in preventing local breast cancer recurrence and improving incision wound healing in a mouse model.
Nanoscale 2012;4(18):5686-93.
2012: Yujun Wang; Cheng Wang; YingJing Wang; ChangYang Gong; Gang Guo; Feng Luo; Zhiyong Qian
Polysorbate 80 coated poly (ɛ-caprolactone)-poly (ethylene glycol)-poly (ɛ-caprolactone) micelles for paclitaxel delivery.
International journal of pharmaceutics 2012;434(1-2):1-8.
2012: ChangYang Gong; Gang Guo; Bing Kan; Feng Luo; XiaoRong Qi; Zhiyong Qian; YuJun Wang; QinJie Wu; Bing Yang; Xia Zhao; Yuquan Wei
Improving intraperitoneal chemotherapeutic effect and preventing postsurgical adhesions simultaneously with biodegradable micelles.
Nanomedicine : nanotechnology, biology, and medicine 2012;8(6):963-73.
2012: ShaoZhi Fu; Feng Luo; Jingcong Luo; PeiYan Ni; BeiYu Wang; Lan Zheng; BingYang Chu; Zhiyong Qian
Injectable and thermo-sensitive PEG-PCL-PEG copolymer/collagen/n-HA hydrogel composite for guided bone regeneration.
Biomaterials 2012;33(19):4801-9.
2012: Changyang Gong; Feng Luo; Cheng Wang; Yujun Wang; Qinjie Wu; Doudou Zhang; Zhiyong Qian
Efficient inhibition of colorectal peritoneal carcinomatosis by drug loaded micelles in thermosensitive hydrogel composites.
Nanoscale 2012;4(10):3095-104.
2012: Yunfeng Lin; Zhiyong Qian
Absorption, pharmacokinetics and disposition of biodegradable nanoscale preparations.
Current drug metabolism 2012;13(4):337.
2012: Cheng Wang; Jing Wang; Xuemei Yang; Tiezhu Chen; Yunfeng Lin; Zhiqiang Luo; Xiongfei Pan; Zhiyong Qian; Xiaoxiao Cai
Absorption, pharmacokinetics and disposition of biodegradable nanoscale preparations.
Current drug metabolism 2012;13(4):429-39.
2012: Xiawei Wei; Zhirong Zhang; Zhiyong Qian
Pharmacokinetics and in vivo fate of drug loaded chitosan nanoparticles.
Current drug metabolism 2012;13(4):364-71.
2012: YuJun Wang; Zhiyong Qian; Cheng Wang; ChangYang Gong; MaLing Gou; Yun Feng Lin; Feng Luo
Pharmacokinetics and disposition of nanomedicine using biodegradable PEG/PCL polymers as drug carriers.
Current drug metabolism 2012;13(4):338-53.
2012: Jinrong Peng; Tingting Qi; Min Fan; He Li; Jinfeng Liao; Feng Luo; Zhiyong Qian
Synthesis and characterization of novel dual-responsive nanogels and their application as drug delivery systems.
Nanoscale 2012;4(8):2694-704.
2012: XingMei Duan; Xiang Gao; MaLing Gou; MeiJuan Huang; Ke Men; Zhiyong Qian; Pan Wang; Lijuan Chen; Yuquan Wei
Treating colon cancer with a suicide gene delivered by self-assembled cationic MPEG-PCL micelles.
Nanoscale 2012;4(7):2400-7.
2012: Bingxin Xue; Feng Luo; XiaoHai Tang; Yingjing Wang; Yujun Wang; Chunjie Wu; Ping Xie; Zhiyong Qian
Biodegradable self-assembled MPEG-PCL micelles for hydrophobic oridonin delivery in vitro.
Journal of biomedical nanotechnology 2012;8(1):80-9.
2012: Lulu Cai; Xiang Chen; Xingmei Duan; Xia Li; Zhiyong Qian; Neng Qiu; Wenwen Wang; Xianhuo Wang; Yuquan Wei; Jiaolin Wen; Li Yang; Lijuan Chen
Peptide ligand and PEG-mediated long-circulating liposome targeted to FGFR overexpressing tumor in vivo.
International journal of nanomedicine 2012;7():4499-510.
2012: Bi Lan Wang; Bowen Yang; Xia Zhao; Xiang Gao; Ma Ling Gou; Mei Juan Huang; Ning Huang; Ke Men; Zhiyong Qian; Jinfeng Qiu; Yu Quan Wei
Treating acute cystitis with biodegradable micelle-encapsulated quercetin.
International journal of nanomedicine 2012;7():2239-47.
2012: JinFeng Liao; Feng Luo; Cheng Wang; YuJun Wang; Zhiyong Qian
Recent advances in formation, properties, and applications of polymersomes.
Current pharmaceutical design 2012;18(23):3432-41.
2012: Shuai Shi; Yingjing Wang; Xuechen Zhu; Tao Zuo; Qingfa Guo; Feng Luo; Zhiyong Qian
Self-assembled mPEG-PCL-g-PEI micelles for simultaneous codelivery of chemotherapeutic drugs and DNA: synthesis and characterization in vitro.
International journal of nanomedicine 2012;7():1749-59.
2012: Jing Li; Ga Liao; Zhiyong Qian; Hui Wang; Ruinan Wang; Yun Wang; Zhiyong Wang; Zhi Wang; Liang Xie; Xiaoping Xu; Dunfang Zhang; Min Zhou; Xikun Zhou; Yu Zhou; Liangyin Chu; Peng Deng; Xiaodong Feng; Ning Geng; Changyang Gong; Ning Ji; Qianming Chen
Biodegradable thermosensitive hydrogel for SAHA and DDP delivery: therapeutic effects on oral squamous cell carcinoma xenografts.
PloS one 2012;7(4):e33860.
2012: Bing Yang; Xia Zhao; Qian Zhong; ShengTao Zhou; ChangYang Gong; ZhengYu Li; Feng Luo; XiaoRong Qi; Zhiyong Qian
Preventing postoperative abdominal adhesions in a rat model with PEG-PCL-PEG hydrogel.
International journal of nanomedicine 2012;7():547-57.
2012: Pei-Yan Ni; Zhiyong Qian; Shuai Shi; Min Fan; Shao-Zhi Fu; Chang-Yang Gong; Feng Luo; Jing-cong Luo; Zhi-Ming Yang
Synthesis and characterization of injectable, thermosensitive, and biocompatible acellular bone matrix/poly(ethylene glycol)-poly (ε-caprolactone)-poly(ethylene glycol) hydrogel composite.
Journal of biomedical materials research. Part A 2012;100(1):171-9.
2011: Mei Dai; Shaozhi Fu; Maling Gou; Feng Luo; Jia Song; Xu Xu; Zhiyong Qian
Preparation of camptothecin-loaded PCEC microspheres for the treatment of colorectal peritoneal carcinomatosis and tumor growth in mice.
Cancer letters 2011;312(2):189-96.
2011: Gang Guo; Hang Liang; Feng Luo; Zhiyong Qian; Min Fan; Shaozhi Fu; Liangxue Zhou; Yuquan Wei
Preparation of curcumin loaded poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) nanofibers and their in vitro antitumor activity against Glioma 9L cells.
Nanoscale 2011;3(9):3825-32.
2011: Shi Zeng; Zhiyong Qian; Xiaohai Tang; Shaozhi Fu; Gang Guo; Hang Liang; Feng Luo
Preparation and characterization of nano-hydroxyapatite/poly(vinyl alcohol) composite membranes for guided bone regeneration.
Journal of biomedical nanotechnology 2011;7(4):549-57.
2011: Cheng Wang; Yingjing Wang; Yujun Wang; Min Fan; Feng Luo; Zhiyong Qian
Characterization, pharmacokinetics and disposition of novel nanoscale preparations of paclitaxel.
International journal of pharmaceutics 2011;414(1-2):251-9.
2011: Xikun Zhou; Zhongwen Chen; Maling Gou; Jing Li; Xiaolei Li; Xiao Liu; Can Luo; Zhiyong Qian; Ji Qiu; Guobo Shen; Xiu Teng; Zhen Wang; Yuquan Wei; Li Yang; Chuanjiang Yu; Nannan Zhang; Yinbin Zhang; Jiong Li
Antitumoral efficacy by systemic delivery of heparin conjugated polyethylenimine-plasmid interleukin-15 complexes in murine models of lung metastasis.
Cancer science 2011;102(7):1403-9.
2011: Zichao Luo; Xinyun Peng; Huashan Shi; Changyang Gong; Zhiyong Qian; Li Yang
Comparison of the protective effects of truncated bFGF and native bFGF against murine lung carcinoma.
International journal of molecular medicine 2011;28(1):3-8.
2011: MaLing Gou; Feng Luo; Ke Men; BiLan Wang; XiaWei Wei; Yuquan Wei; Xia Zhao; Zhiyong Qian
PCL/PEG copolymeric nanoparticles: potential nanoplatforms for anticancer agent delivery.
Current drug targets 2011;12(8):1131-50.
2011: Juan Zhang; Xiuhong Wang; Maling Gou; Yingchun Gu; Gang Guo; Feng Luo; Ke Men; Zhiyong Qian
Preparation of core cross-linked PCL-PEG-PCL micelles for doxorubicin delivery in vitro.
Journal of nanoscience and nanotechnology 2011;11(6):5054-61.
2011: Lan Zheng; Maling Gou; Shengtao Zhou; Tao Yi; Qian Zhong; Zhengyu Li; Xiang He; Xiancheng Chen; Lina Zhou; Yuquan Wei; Zhiyong Qian; Xia Zhao
Antitumor activity of monomethoxy poly(ethylene glycol)-poly (ε-caprolactone) micelle-encapsulated doxorubicin against mouse melanoma.
Oncology reports 2011;25(6):1557-64.
2011: Jinrong Peng; Zhiyong Qian; Bing Wang; Shaozhi Fu; Gang Guo; Ruixia Li; Feng Luo; Dacheng Wu
Preparation and release characteristic of quercetin loaded poly(lactic acid) ultrafine fibers.
Journal of nanoscience and nanotechnology 2011;11(4):3659-68.
2011: Shao Zhi Fu; Xiu Hong Wang; Gang Guo; Shuai Shi; Min Fan; Hang Liang; Feng Luo; Zhiyong Qian
Preparation and properties of nano-hydroxyapatite/PCL-PEG-PCL composite membranes for tissue engineering applications.
Journal of biomedical materials research. Part B, Applied biomaterials 2011;97(1):74-83.
2011: MaLing Gou; Ke Men; HuaShan Shi; MingLi Xiang; Juan Zhang; Jia Song; JianLin Long; Yang Wan; Feng Luo; Xia Zhao; Zhiyong Qian
Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo.
Nanoscale 2011;3(4):1558-67.
2011: MaLing Gou; HuaShan Shi; Gang Guo; Ke Men; Juan Zhang; Lan Zheng; Zhiyong Li; Feng Luo; Zhiyong Qian; Xia Zhao; Yuquan Wei
Improving anticancer activity and reducing systemic toxicity of doxorubicin by self-assembled polymeric micelles.
Nanotechnology 2011;22(9):095102.
2011: Jinrong Peng; Xiaolu Li; Gang Guo; Tingqiang Yi; Shaozhi Fu; Hang Liang; Feng Luo; Xia Zhao; Yuquan Wei; Zhiyong Qian
Preparation and characterization of poly(vinyl alcohol)/poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone)/nano-hydroxyapatite composite membranes for tissue engineering.
Journal of nanoscience and nanotechnology 2011;11(3):2354-60.
2011: Hongxin Deng; Qingyuan Jiang; Yang Yang; Shuang Zhang; Yongping Ma; Gang Xie; Xiang Chen; Zhiyong Qian; Yanjun Wen; Jiong Li; Jinliang Yang; Lijuan Chen; Xia Zhao; Yuquan Wei
Intravenous liposomal delivery of the short hairpin RNAs against Plk1 controls the growth of established human hepatocellular carcinoma.
Cancer biology & therapy 2011;11(4):401-9.
2011: Ling Zhang; Shuang Zhang; Xia Zhao; Xiang Gao; Maling Gou; Meijuan Huang; Ning Huang; Ke Men; Zhiyong Qian; Jinfeng Qiu; Bilan Wang; Yuquan Wei
Gene therapy for C-26 colon cancer using heparin-polyethyleneimine nanoparticle-mediated survivin T34A.
International journal of nanomedicine 2011;6():2419-27.
2011: Qing Fa Guo; Ting Ting Liu; Feng Luo; Shuai Shi; Xiu Hong Wang; Xi Yan; Zhiyong Qian
Synthesis and properties of a novel biodegradable poly(ester amine) copolymer based on poly(L-lactide) and low molecular weight polyethylenimine for gene delivery.
International journal of nanomedicine 2011;6():1641-9.
2011: Zhizhong Xu; Peng Zhang; Xinyu Zhao; Qingfa Guo; Zhiyong Qian; Guobo Shen; Yuquan Wei; Huanhuan Wu; Xiangying Xia; Shufang Liang
Comparisons of three polyethyleneimine-derived nanoparticles as a gene therapy delivery system for renal cell carcinoma.
Journal of translational medicine 2011;9(1):46.
2011: Jing-cong Luo; Wei Chen; Xiao-He Chen; Tingwu Qin; Yong-Can Huang; Hui-qi Xie; Xiu-qun Li; Zhiyong Qian; Zhi-ming Yang
A multi-step method for preparation of porcine small intestinal submucosa (SIS).
Biomaterials 2011;32(3):706-13.
2011: Xingyi Li; Xiangye Kong; Juan Zhang; Yingjing Wang; Yujun Wang; Shuai Shi; Gang Guo; Feng Luo; Xia Zhao; Yuquan Wei; Zhiyong Qian
A novel composite hydrogel based on chitosan and inorganic phosphate for local drug delivery of camptothecin nanocolloids.
Journal of pharmaceutical sciences 2011;100(1):232-41.
2010: Ke Men; Ma Ling Gou; Qing Fa Guo; Xiu Hong Wang; Shuai Shi; Bing Kan; Mei Juan Huang; Feng Luo; Li Juan Chen; Xia Zhao; Zhiyong Qian; Shu Fang Liang; Yu Quan Wei
A novel drug and gene co-delivery system based on Poly(epsilon-caprolactone)-Poly(ethylene glycol)-Poly(epsilon-caprolactone) grafted polyethyleneimine micelle.
Journal of nanoscience and nanotechnology 2010;10(12):7958-64.
2010: Lina Zhou; Xingyi Li; Xiancheng Chen; Zhiyong Li; Xianping Liu; Shengtao Zhou; Qian Zhong; Tao Yi; Yuquan Wei; Xia Zhao; Zhiyong Qian
In vivo antitumor and antimetastatic activities of camptothecin encapsulated with N-trimethyl chitosan in a preclinical mouse model of liver cancer.
Cancer letters 2010;297(1):56-64.
2010: MaLing Gou; Ke Men; Juan Zhang; YuHua Li; Jia Song; Shan Luo; HuaShan Shi; Yanjun Wen; Gang Guo; MeiJuan Huang; Xia Zhao; Zhiyong Qian; Yuquan Wei
Efficient inhibition of C-26 colon carcinoma by VSVMP gene delivered by biodegradable cationic nanogel derived from polyethyleneimine.
ACS nano 2010;4(10):5573-84.
2010: Lina Zhou; Licheng Du; Xiancheng Chen; Xingyi Li; Zhiyong Li; Yuan Wen; Zhengyu Li; Xiang He; Yuquan Wei; Xia Zhao; Zhiyong Qian
The antitumor and antimetastatic effects of N-trimethyl chitosan-encapsulated camptothecin on ovarian cancer with minimal side effects.
Oncology reports 2010;24(4):941-8.
2010: Tingting Liu; Xiujun Yu; Bing Kan; Qingfa Guo; Xiuhong Wang; Shuai Shi; Gang Guo; Feng Luo; Xia Zhao; Yuquan Wei; Zhiyong Qian
Enhanced gene delivery using biodegradable poly(ester amine)s (PEAs) based on low-molecular-weight polyethylenimine and poly(epsilon-caprolactone)-pluronic-poly(epsilon-caprolactone).
Journal of biomedical nanotechnology 2010;6(4):351-9.
2010: Bilan Wang; Maling Gou; Xiuling Zheng; Xiawei Wei; Changyang Gong; Xiuhong Wang; Yinglan Zhao; Feng Luo; Lijuan Chen; Zhiyong Qian; Li Yang
Co-delivery honokiol and doxorubicin in MPEG-PLA nanoparticles.
Journal of nanoscience and nanotechnology 2010;10(7):4166-72.
2010: XiuLing Zheng; XiuHong Wang; MaLing Gou; Juan Zhang; Ke Men; Lijuan Chen; Feng Luo; Xia Zhao; Yuquan Wei; Zhiyong Qian
A novel transdermal honokiol formulation based on Pluronic F127 copolymer.
Drug delivery 2010;17(3):138-44.
2010: MaLing Gou; ChangYang Gong; Juan Zhang; XiuHong Wang; XianHuo Wang; YingChun Gu; Gang Guo; Lijuan Chen; Feng Luo; Xia Zhao; Yuquan Wei; Zhiyong Qian
Polymeric matrix for drug delivery: honokiol-loaded PCL-PEG-PCL nanoparticles in PEG-PCL-PEG thermosensitive hydrogel.
Journal of biomedical materials research. Part A 2010;93(1):219-26.
2010: Shaozhi Fu; Gang Guo; Xinlong Wang; Liangxue Zhou; Tingting Liu; Pengwei Dong; Feng Luo; Yingchun Gu; Xingyu Shi; Xia Zhao; Yuquan Wei; Zhiyong Qian
Preparation and characterization of n-hydroxyapatite/PCL-pluronic-PCL nanocomposites for tissue engineering.
Journal of nanoscience and nanotechnology 2010;10(2):711-8.
2010: Yina Huang; Hong Gao; Maling Gou; Huaxia Ye; Yunke Liu; Yuan Gao; Feng Peng; Zhiyong Qian; Xiaobo Cen; Yinglan Zhao
Acute toxicity and genotoxicity studies on poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) nanomaterials.
Mutation research 2010;696(2):101-6.
2010: Hongxin Deng; Qingyuan Jiang; Shufang Liang; Fei Yan; Shengyan Hou; Zhiyong Qian; Jiong Li; Yanjun Wen; Jinliang Yang; Yuquan Wei
Prokaryotic expression, purification and characterization of a novel pro-apoptosis protein hPNAS-4.
Biotechnology and applied biochemistry 2010;55(2):63-72.
2010: Bing Yang; ChangYang Gong; Zhiyong Qian; Xia Zhao; ZhengYu Li; XiaoRong Qi; ShengTao Zhou; Qian Zhong; Feng Luo; Yuquan Wei
Prevention of post-surgical abdominal adhesions by a novel biodegradable thermosensitive PECE hydrogel.
BMC biotechnology 2010;10():65.
2010: Yongsheng Wang; Changyang Gong; Li Yang; Qinjie Wu; Shuai Shi; Huashan Shi; Zhiyong Qian; Yuquan Wei
5-FU-hydrogel inhibits colorectal peritoneal carcinomatosis and tumor growth in mice.
BMC cancer 2010;10():402.
2010: Xian-Ping Liu; Sheng-Tao Zhou; Xing-Yi Li; Xian-Cheng Chen; Xia Zhao; Zhiyong Qian; Li-Na Zhou; Zhi-Yong Li; Yu-Mei Wang; Qian Zhong; Tao Yi; Zheng-Yu Li; Xiang He; Yu-Quan Wei
Anti-tumor activity of N-trimethyl chitosan-encapsulated camptothecin in a mouse melanoma model.
Journal of experimental & clinical cancer research : CR 2010;29():76.
2009: Shaozhi Fu; Gang Guo; Changyang Gong; Shi Zeng; Hang Liang; Feng Luo; Xiaoning Zhang; Xia Zhao; Yuquan Wei; Zhiyong Qian
Injectable biodegradable thermosensitive hydrogel composite for orthopedic tissue engineering. 1. Preparation and characterization of nanohydroxyapatite/poly(ethylene glycol)-poly(epsilon-caprolactone)-poly(ethylene glycol) hydrogel nanocomposites.
The journal of physical chemistry. B 2009;113(52):16518-25.
2009: Chang-Yang Gong; Shuai Shi; Xin-Yun Peng; Bing Kan; Li Yang; Mei-Juan Huang; Feng Luo; Xia Zhao; Yu-Quan Wei; Zhiyong Qian
Biodegradable thermosensitive injectable PEG-PCL-PEG hydrogel for bFGF antigen delivery to improve humoral immunity.
Growth factors (Chur, Switzerland) 2009;27(6):377-83.
2009: Chang Yang Gong; Shuai Shi; Peng Wei Dong; Bing Yang; Xiao Rong Qi; Gang Guo; Ying Chun Gu; Xia Zhao; Yu Quan Wei; Zhiyong Qian
Biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PCL-PEG-PCL hydrogel: part 1--Synthesis, characterization, and acute toxicity evaluation.
Journal of pharmaceutical sciences 2009;98(12):4684-94.
2009: MaLing Gou; Lan Wu; QinQin Yin; QingFa Guo; Gang Guo; Jin Liu; Xia Zhao; YuQuan Wei; Zhiyong Qian
Transdermal anaesthesia with lidocaine nano-formulation pretreated with low-frequency ultrasound in rats model.
Journal of nanoscience and nanotechnology 2009;9(11):6360-5.
2009: Xu Xu; ShaoZhi Fu; Ke Wang; WenJuan Jia; Gang Guo; XiuLing Zheng; PengWei Dong; QingFa Guo; Zhiyong Qian
Preparation and characterization of vitamin-12 loaded biodegradable pH-sensitive microgels.
Journal of microencapsulation 2009;26(7):642-8.
2009: ChangYang Gong; Shuai Shi; Lan Wu; MaLing Gou; QinQin Yin; QingFa Guo; PengWei Dong; Fan Zhang; Feng Luo; Xia Zhao; Yuquan Wei; Zhiyong Qian
Biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PCL-PEG-PCL hydrogel. Part 2: sol-gel-sol transition and drug delivery behavior.
Acta biomaterialia 2009;5(9):3358-70.
2009: MaLing Gou; XiuLing Zheng; Ke Men; Juan Zhang; Lan Zheng; XiuHong Wang; Feng Luo; YinLan Zhao; Xia Zhao; Yuquan Wei; Zhiyong Qian
Poly(epsilon-caprolactone)/poly(ethylene glycol)/poly(epsilon-caprolactone) nanoparticles: preparation, characterization, and application in doxorubicin delivery.
The journal of physical chemistry. B 2009;113(39):12928-33.
2009: Q-Q Yin; L Wu; M-L Gou; Zhiyong Qian; W-S Zhang; J Liu
Long-lasting infiltration anaesthesia by lidocaine-loaded biodegradable nanoparticles in hydrogel in rats.
Acta anaesthesiologica Scandinavica 2009;53(9):1207-13.
2009: Chang Yang Gong; Qin Jie Wu; Peng Wei Dong; Shuai Shi; Shao Zhi Fu; Gang Guo; Hua-zi Hu; Xia Zhao; Yu-Quan Wei; Zhiyong Qian
Acute toxicity evaluation of biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PEG-PCL-PEG hydrogel.
Journal of biomedical materials research. Part B, Applied biomaterials 2009;91(1):26-36.
2009: Chang Yang Gong; Peng Wei Dong; Shuai Shi; Shao Zhi Fu; Jin Liang Yang; Gang Guo; Xia Zhao; Yu Quan Wei; Zhiyong Qian
Thermosensitive PEG-PCL-PEG hydrogel controlled drug delivery system: sol-gel-sol transition and in vitro drug release study.
Journal of pharmaceutical sciences 2009;98(10):3707-17.
2009: Qingfa Guo; Shuai Shi; Xiuhong Wang; Bing Kan; Yingchun Gu; Xingyu Shi; Feng Luo; Xia Zhao; Yuquan Wei; Zhiyong Qian
Synthesis of a novel biodegradable poly(ester amine) (PEAs) copolymer based on low-molecular-weight polyethyleneimine for gene delivery.
International journal of pharmaceutics 2009;379(1):82-9.
2009: MaLing Gou; XiuLing Zheng; Ke Men; Juan Zhang; BiLan Wang; Lei Lv; XiuHong Wang; YinLan Zhao; Feng Luo; Lijuan Chen; Xia Zhao; Yuquan Wei; Zhiyong Qian
Self-assembled hydrophobic honokiol loaded MPEG-PCL diblock copolymer micelles.
Pharmaceutical research 2009;26(9):2164-73.
2009: Lei Liu; Hongxin Deng; Yongsheng Wang; Ping Chen; Yang Yang; Hanshuo Yang; Xiancheng Chen; Lijuan Chen; Wen Zhu; Shufang Liang; Jinliang Yang; Zhiyong Qian; Jiong Li; Yanjun Wen; Bin Kan; Yongqiu Mao; Xia Zhao; Yuquan Wei
A novel strategy for tumour therapy combining cell apoptosis and active immunity induced by caspy2, a zebrafish caspase.
Journal of cellular and molecular medicine 2009;13(8B):2271-81.
2009: Jian Zhao; Maling Gou; Mei Dai; Xingyi Li; Mei Cao; Meijuan Huang; Yanjun Wen; Bing Kan; Zhiyong Qian; Yuquan Wei
Preparation, characterization, and in vitro cytotoxicity study of cationic PCL-pluronic-PCL (PCFC) nanoparticles for gene delivery.
Journal of biomedical materials research. Part A 2009;90(2):506-13.
2009: ChangYang Gong; Shuai Shi; XiuHong Wang; YuJun Wang; ShaoZhi Fu; PengWei Dong; Lijuan Chen; Xia Zhao; Yuquan Wei; Zhiyong Qian
Novel composite drug delivery system for honokiol delivery: self-assembled poly(ethylene glycol)-poly(epsilon-caprolactone)-poly(ethylene glycol) micelles in thermosensitive poly(ethylene glycol)-poly(epsilon-caprolactone)-poly(ethylene glycol) hydrogel.
The journal of physical chemistry. B 2009;113(30):10183-8.
2009: Xingyi Li; QingFa Guo; XiuLing Zheng; XiangYe Kong; Shuai Shi; Lijuan Chen; Xia Zhao; Yuquan Wei; Zhiyong Qian
Preparation of honokiol-loaded chitosan microparticles via spray-drying method intended for pulmonary delivery.
Drug delivery 2009;16(3):160-6.
2009: Fang Fang; Chang Yang Gong; Peng Wei Dong; Shao Zhi Fu; Ying Chun Gu; Gang Guo; Xia Zhao; Yu-Quan Wei; Zhiyong Qian
Acute toxicity evaluation of in situ gel-forming controlled drug delivery system based on biodegradable poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone) copolymer.
Biomedical materials (Bristol, England) 2009;4(2):025002.
2009: XiaWei Wei; ChangYang Gong; Shuai Shi; ShaoZhi Fu; Ke Men; Shi Zeng; XiuLing Zheng; MaLing Gou; Lijuan Chen; Liyan Qiu; Zhiyong Qian
Self-assembled honokiol-loaded micelles based on poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone) copolymer.
International journal of pharmaceutics 2009;369(1-2):170-5.
2009: ChangYang Gong; Shuai Shi; PengWei Dong; Bing Kan; MaLing Gou; XianHuo Wang; XingYi Li; Feng Luo; Xia Zhao; Yuquan Wei; Zhiyong Qian
Synthesis and characterization of PEG-PCL-PEG thermosensitive hydrogel.
International journal of pharmaceutics 2009;365(1-2):89-99.
2009: Mei Dai; Xiuling Zheng; Xu Xu; Xiangye Kong; Xingyi Li; Gang Guo; Feng Luo; Xia Zhao; Yu Quan Wei; Zhiyong Qian
Chitosan-alginate sponge: preparation and application in curcumin delivery for dermal wound healing in rat.
Journal of biomedicine & biotechnology 2009;2009():595126.
2009: Chang Yang Gong; Shuai Shi; Peng Wei Dong; Xiu Ling Zheng; Shao Zhi Fu; Gang Guo; Jing Liang Yang; Yu-Quan Wei; Zhiyong Qian
In vitro drug release behavior from a novel thermosensitive composite hydrogel based on Pluronic f127 and poly(ethylene glycol)-poly(epsilon-caprolactone)-poly(ethylene glycol) copolymer.
BMC biotechnology 2009;9():8.
2009: Ze-jun Lu; Qi-fang Song; Sa-sa Jiang; Qi Song; Wei Wang; Gao-hua Zhang; Bing Kan; Li-juan Chen; Jin-liang Yang; Feng Luo; Zhiyong Qian; Yu-Quan Wei; Lantu Gou
Identification of ATP synthase beta subunit (ATPB) on the cell surface as a non-small cell lung cancer (NSCLC) associated antigen.
BMC cancer 2009;9():16.
2008: Changyang Gong; Yingchun Gu; Zhen Xie; Xihui Xie; Caibing Liu; Bing Kan; Mingjing Tu; Yuquan Wei; Zhiyong Qian
[Synthesis and characterization of thermosensitive hydrogel based on PEG-PCL-PEG block copolymers].
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 2008;25(5):1121-5.
2008: Mei Juan Huang; Ma Ling Gou; Zhiyong Qian; Mei Dai; Xing Yi Li; Mei Cao; Ke Wang; Jian Zhao; Jing Liang Yang; You Lu; Ming Jing Tu; Yu Quan Wei
One-step preparation of poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone) nanoparticles for plasmid DNA delivery.
Journal of biomedical materials research. Part A 2008;86(4):979-86.
2008: Wenjuan Jia; YingChun Gu; MaLing Gou; Mei Dai; XingYi Li; Bing Kan; JinLiang Yang; QiFang Song; Yuquan Wei; Zhiyong Qian
Preparation of biodegradable polycaprolactone/poly (ethylene glycol)/polycaprolactone (PCEC) nanoparticles.
Drug delivery 2008;15(7):409-16.
2008: Maling Gou; Xingyi Li; Mei Dai; Changyang Gong; Xianhuo Wang; Yao Xie; Hongxin Deng; Lijuan Chen; Xia Zhao; Zhiyong Qian; Yuquan Wei
A novel injectable local hydrophobic drug delivery system: Biodegradable nanoparticles in thermo-sensitive hydrogel.
International journal of pharmaceutics 2008;359(1-2):228-33.
2008: Ma Ling Gou; Mei Dai; Xing Yi Li; Xian Huo Wang; Chang Yang Gong; Yao Xie; Ke Wang; Xia Zhao; Zhiyong Qian; Yu Quan Wei
Preparation and characterization of honokiol nanoparticles.
Journal of materials science. Materials in medicine 2008;19(7):2605-8.
2008: Maling Gou; Mei Dai; XingYi Li; Li Yang; MeiJuan Huang; YongShen Wang; Bing Kan; You Lu; Yuquan Wei; Zhiyong Qian
Preparation of mannan modified anionic PCL-PEG-PCL nanoparticles at one-step for bFGF antigen delivery to improve humoral immunity.
Colloids and surfaces. B, Biointerfaces 2008;64(1):135-9.
2008: Maling Gou; Mei Dai; Yinchun Gu; Xingyi Li; Yanjun Wen; Li Yang; Ke Wang; Yuquan Wei; Zhiyong Qian
Basic fibroblast growth factor loaded biodegradable PCL-PEG-PCL copolymeric nanoparticles: preparation, in vitro release and immunogenicity study.
Journal of nanoscience and nanotechnology 2008;8(5):2357-61.
2008: Xia Deng; Zhiqing Chen; Zhiyong Qian; Caibing Liu; Hong Li
[A novel nano-hydroxyapatite/aliphatic polyesteramide composite].
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 2008;25(2):378-81, 392.
2008: GuoTao Chao; Zhiyong Qian; Mei Juan Huang; Bing Kan; Ying Chun Gu; Chang Yang Gong; Jin Liang Yang; Ke Wang; Mei Dai; Xing Yi Li; Ma Ling Gou; MingJing Tu; Yu Quan Wei
Synthesis, characterization, and hydrolytic degradation behavior of a novel biodegradable pH-sensitive hydrogel based on polycaprolactone, methacrylic acid, and poly(ethylene glycol).
Journal of biomedical materials research. Part A 2008;85(1):36-46.
2008: Ma Ling Gou; Zhiyong Qian; Hui Wang; Yong Bo Tang; Mei Juan Huang; Bing Kan; Yan Juan Wen; Mei Dai; Xing Yi Li; Chang Yang Gong; MingJing Tu
Preparation and characterization of magnetic poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone) microspheres.
Journal of materials science. Materials in medicine 2008;19(3):1033-41.
2008: Xian Chen; Zhiyong Qian; MaLing Gou; GuoTao Chao; YangDe Zhang; YingChun Gu; MeiJuan Huang; JiWei Wang; YiFeng Pan; YuQuan Wei; JianPing Chen; MingJing Tu
Acute oral toxicity evaluation of biodegradable and pH-sensitive hydrogel based on polycaprolactone, poly(ethylene glycol) and methylacrylic acid (MAA).
Journal of biomedical materials research. Part A 2008;84(3):589-97.
2008: Cai Bing Liu; Chang Yang Gong; Mei Juan Huang; Ji Wei Wang; Yi Feng Pan; Yang-de Zhang; Guo Zheng Li; Ma Ling Gou; Ke Wang; Ming Jing Tu; Yu-Quan Wei; Zhiyong Qian
Thermoreversible gel-sol behavior of biodegradable PCL-PEG-PCL triblock copolymer in aqueous solutions.
Journal of biomedical materials research. Part B, Applied biomaterials 2008;84(1):165-75.
2007: CaiBing Liu; Zhiyong Qian; WenJuan Jia; MeiJuan Huang; GuoTao Chao; ChangYang Gong; HongXin Deng; YanJun Wen; JinLiang Yang; MaLing Gou; MingJing Tu
Synthesis, characterization and hydrolytic degradation study of polyetheresteramide copolymers based on epsilon-caprolactone, 6-aminocaproic acid, and poly(ethylene glycol).
Journal of materials science. Materials in medicine 2007;18(10):2085-91.
2007: GuoTao Chao; LinYu Fan; WenJuan Jia; Zhiyong Qian; YingChun Gu; CaiBing Liu; XiPing Ni; Jun Li; HongXin Deng; ChangYang Gong; MaLing Gou; Ke Lei; AnLiang Huang; CanHua Huang; JinLiang Yang; Bing Kan; MingJing Tu
Synthesis, characterization and hydrolytic degradation of degradable poly(butylene terephthalate)/poly(ethylene glycol) (PBT/PEG) copolymers.
Journal of materials science. Materials in medicine 2007;18(3):449-55.
2007: Wen Juan Jia; Jian Gang Liu; Yang De Zhang; Ji Wei Wang; Jun Wang; Cheng Yi Sun; Yi Feng Pan; Chao Yu; Guo Zheng Li; Heng Zhang; Ma Ling Gou; Ming Jing Tu; Zhiyong Qian
Preparation, characterization, and optimization of pancreas-targeted 5-Fu loaded magnetic bovine serum albumin microspheres.
Journal of drug targeting 2007;15(2):140-5.
2005: Caibing Liu; Yingchun Gu; Zhiyong Qian; Linyu Fan; Jun Li; GuoTao Chao; MingJing Tu; Wenjuan Jia
Hydrolytic degradation behavior of biodegradable polyetheresteramide-based polyurethane copolymers.
Journal of biomedical materials research. Part A 2005;75(2):465-71.
2004: Zhiyong Qian; Sai Li; Yi He; Hailian Zhang; Xiaobo Liu
Hydrolytic degradation study of biodegradable polyesteramide copolymers based on epsilon-caprolactone and 11-aminoundecanoic acid.
Biomaterials 2004;25(11):1975-81.