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Atsushi Takeda

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Ohito Tano; Takafumi Hasegawa; Kimihiko Kaneko; Akio Kikuchi; Atsushi Takeda; Masashi Aoki
Dopaminergic drug-induced jaw-opening dystonia in a patient with progressive supranuclear palsy.
Atsushi Takeda
[Severe olfactory dysfunction is a predictor of dementia with Parkinson's disease].
Akio Kikuchi; Michiko Kobayashi; Masatoshi Konno; Emiko Miura; Etsuro Mori; Yoshiyuki Nishio; Naoto Sugeno; Kyoko Suzuki; Shoki Takahashi; Masashi Aoki; Toru Baba; Hiroshi Fukuda; Takafumi Hasegawa; Kazumi Hirayama; Yoshiyuki Hosokai; Toshiyuki Ishioka; Yasuto Itoyama; Atsushi Takeda
Hypometabolism in the supplementary and anterior cingulate cortices is related to dysphagia in Parkinson's disease: a cross-sectional and 3-year longitudinal cohort study.

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2013: Ohito Tano; Takafumi Hasegawa; Kimihiko Kaneko; Akio Kikuchi; Atsushi Takeda; Masashi Aoki
Dopaminergic drug-induced jaw-opening dystonia in a patient with progressive supranuclear palsy.
Rinshō shinkeigaku = Clinical neurology 2013;53(4):308-11.
2013: Atsushi Takeda
[Severe olfactory dysfunction is a predictor of dementia with Parkinson's disease].
Rinshō shinkeigaku = Clinical neurology 2013;53(2):91-7.
2013: Akio Kikuchi; Michiko Kobayashi; Masatoshi Konno; Emiko Miura; Etsuro Mori; Yoshiyuki Nishio; Naoto Sugeno; Kyoko Suzuki; Shoki Takahashi; Masashi Aoki; Toru Baba; Hiroshi Fukuda; Takafumi Hasegawa; Kazumi Hirayama; Yoshiyuki Hosokai; Toshiyuki Ishioka; Yasuto Itoyama; Atsushi Takeda
Hypometabolism in the supplementary and anterior cingulate cortices is related to dysphagia in Parkinson's disease: a cross-sectional and 3-year longitudinal cohort study.
BMJ open 2013;3(3):.
2013: Kimihiko Kaneko; Akio Kikuchi; Hiroshi Saito; Atsushi Takeda; Ohito Tano; Maki Tateyama; Osamu Watanabe; Masaru Yoshioka; Takafumi Hasegawa; Masashi Aoki
Anti-voltage-gated potassium channel antibody is associated with chronic autonomic and sensory neuropathy.
Journal of neurology 2013;260(1):315-7.
2012: Atsushi Takeda; Masahiro Tachi
[Evaluation of cohesive silicone breast implants].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 7():645-8.
2012: Toru Baba; Atsushi Takeda
[Recent advances in imaging in Parkinson disease].
Brain and nerve = Shinkei kenkyū no shinpo 2012;64(4):423-32.
2012: Masatoshi Konno; Emiko Miura; Tsutomu Sasaki; Naoto Sugeno; Masashi Aoki; Toru Baba; Fabienne C Fiesel; Takafumi Hasegawa; Yasuto Itoyama; Akio Kikuchi; Atsushi Takeda
Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy.
Molecular neurodegeneration 2012;7():38.
2012: Kotaro Hiraoka; Kinya Hisanaga; Ren Iwata; Nobuyuki Okamura; Atsushi Takeda; Manabu Tashiro; Kazuhiko Yanai; Toshikatsu Fujii; Yoshihito Funaki; Akiko Hayashi; Etsuro Mori
Cholinergic deficit and response to donepezil therapy in Parkinson's disease with dementia.
European neurology 2012;68(3):137-43.
2012: Yoichi Sawada; Kyoko Suzuki; Shoki Takahashi; Atsushi Takeda; Hiroshi Fukuda; Kazumi Hirayama; Yoshiyuki Hosokai; Toshiyuki Ishioka; Yasuto Itoyama; Yoshiyuki Nishio; Etsuro Mori
Attentional set-shifting deficit in Parkinson's disease is associated with prefrontal dysfunction: an FDG-PET study.
PloS one 2012;7(6):e38498.
2012: Toru Baba; Hiroshi Fukuda; Takafumi Hasegawa; Kazumi Hirayama; Yoshiyuki Hosokai; Yasuto Itoyama; Shigenori Kanno; Akio Kikuchi; Masatoshi Konno; Etsuro Mori; Yoshiyuki Nishio; Naoto Sugeno; Kyoko Suzuki; Shoki Takahashi; Masashi Aoki; Atsushi Takeda
Severe olfactory dysfunction is a prodromal symptom of dementia associated with Parkinson's disease: a 3 year longitudinal study.
Brain : a journal of neurology 2012;135(Pt 1):161-9.
2011: Atsushi Takeda
[Parkinson's disease with dementia (PDD)].
Nihon rinsho. Japanese journal of clinical medicine 2011;69 Suppl 10(Pt 2):350-5.
2011: Akio Kikuchi; Masatoshi Konno; Naoto Sugeno; Toru Baba; Takafumi Hasegawa; Atsushi Takeda
Differentiating Parkinson's disease from multiple system atrophy by [123I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test.
Parkinsonism & related disorders 2011;17(9):698-700.
2011: Shigenori Kanno; Hirokazu Kikuchi; Nobuhito Abe; Risa Hanaki; Akiko Hayashi; Kotaro Hiraoka; Osamu Iizuka; Yasuto Itoyama; Yoshiyuki Nishio; Makoto Saito; Masahito Takagi; Shoki Takahashi; Atsushi Takeda; Makoto Uchiyama; Hiroshi Yamasaki; Etsuro Mori
White matter involvement in idiopathic normal pressure hydrocephalus: a voxel-based diffusion tensor imaging study.
Journal of neurology 2011;258(11):1949-57.
2011: Toshiyuki Ishioka; Kazumi Hirayama; Yoshiyuki Hosokai; Atsushi Takeda; Kyoko Suzuki; Yoshiyuki Nishio; Yoichi Sawada; Shoki Takahashi; Hiroshi Fukuda; Yasuto Itoyama; Etsuro Mori
Illusory misidentifications and cortical hypometabolism in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2011;26(5):837-43.
2011: Toru Baba; Atsushi Takeda; Akio Kikuchi; Yoshiyuki Nishio; Yoshiyuki Hosokai; Kazumi Hirayama; Takafumi Hasegawa; Naoto Sugeno; Kyoko Suzuki; Etsuro Mori; Shoki Takahashi; Hiroshi Fukuda; Yasuto Itoyama
Association of olfactory dysfunction and brain. Metabolism in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2011;26(4):621-8.
2010: Takafumi Hasegawa; Toru Baba; Michiko Kobayashi; Masatoshi Konno; Naoto Sugeno; Akio Kikuchi; Yasuto Itoyama; Atsushi Takeda
Role of TPPP/p25 on α-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy.
Neurochemistry international 2010;57(8):857-66.
2010: Atsushi Takeda; Naohiro Saito; Toru Baba; Akio Kikuchi; Naoto Sugeno; Michiko Kobayashi; Takafumi Hasegawa; Yasuto Itoyama
Functional imaging studies of hyposmia in Parkinson's disease.
Journal of the neurological sciences 2010;289(1-2):36-9.
2009: Wataru Satake; Yuko Nakabayashi; Ikuko Mizuta; Yushi Hirota; Chiyomi Ito; Michiaki Kubo; Takahisa Kawaguchi; Tatsuhiko Tsunoda; Masahiko Watanabe; Atsushi Takeda; Hiroyuki Tomiyama; Kenji Nakashima; Kazuko Hasegawa; Fumiya Obata; Takeo Yoshikawa; Hideshi Kawakami; Saburo Sakoda; Mitsutoshi Yamamoto; Nobutaka Hattori; Miho Murata; Yusuke Nakamura; Tatsushi Toda
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.
Nature genetics 2009;41(12):1303-7.
2009: Nobuhito Abe; Toshikatsu Fujii; Kazumi Hirayama; Atsushi Takeda; Yoshiyuki Hosokai; Toshiyuki Ishioka; Yoshiyuki Nishio; Kyoko Suzuki; Yasuto Itoyama; Shoki Takahashi; Hiroshi Fukuda; Etsuro Mori
Do parkinsonian patients have trouble telling lies? The neurobiological basis of deceptive behaviour.
Brain : a journal of neurology 2009;132(Pt 5):1386-95.
2009: Yoshiyuki Hosokai; Yoshiyuki Nishio; Kazumi Hirayama; Atsushi Takeda; Toshiyuki Ishioka; Yoichi Sawada; Kyoko Suzuki; Yasuto Itoyama; Shoki Takahashi; Hiroshi Fukuda; Etsuro Mori
Distinct patterns of regional cerebral glucose metabolism in Parkinson's disease with and without mild cognitive impairment.
Movement disorders : official journal of the Movement Disorder Society 2009;24(6):854-62.
2009: Toru Baba; Ichiro Nakashima; Takashi Kanbayashi; Masatoshi Konno; Toshiyuki Takahashi; Kazuo Fujihara; Tatsuro Misu; Atsushi Takeda; Yusei Shiga; Hiromasa Ogawa; Yasuto Itoyama
Narcolepsy as an initial manifestation of neuromyelitis optica with anti-aquaporin-4 antibody.
Journal of neurology 2009;256(2):287-8.
2009: Bo Su; Haihua Liu; Xinglong Wang; Shu G Chen; Sandra L Siedlak; Eisaku Kondo; Raymond Choi; Atsushi Takeda; Rudy J Castellani; George Perry; Mark A. Smith; Xiongwei Zhu; Hyoung-gon Lee
Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease.
Molecular neurodegeneration 2009;4():32.
2008: Atsushi Takeda; Naoto Sugeno; Takafumi Hasegawa; Michiko Kobayashi; Akio Kikuchi
[Cellular pathophysiology of Parkinson's disease].
Rinshō shinkeigaku = Clinical neurology 2008;48(11):984-5.
2008: Naoto Sugeno; Atsushi Takeda; Takafumi Hasegawa; Michiko Kobayashi; Akio Kikuchi; Fumiaki Mori; Koichi Wakabayashi; Yasuto Itoyama
Serine 129 phosphorylation of alpha-synuclein induces unfolded protein response-mediated cell death.
The Journal of biological chemistry 2008;283(34):23179-88.
2008: Ikuko Mizuta; Tatsuhiko Tsunoda; Wataru Satake; Yuko Nakabayashi; Masahiko Watanabe; Atsushi Takeda; Kazuko Hasegawa; Kenji Nakashima; Mitsutoshi Yamamoto; Nobutaka Hattori; Miho Murata; Tatsushi Toda
Calbindin 1, fibroblast growth factor 20, and alpha-synuclein in sporadic Parkinson's disease.
Human genetics 2008;124(1):89-94.
2008: Y P Ning; K Kanai; Hiroyuki Tomiyama; Yuanzhe Li; Manabu Funayama; Hiroyo Yoshino; Shigeto Sato; Masato Asahina; S Kuwabara; Atsushi Takeda; T Hattori; Yoshikuni Mizuno; Nobutaka Hattori
PARK9-linked parkinsonism in eastern Asia: mutation detection in ATP13A2 and clinical phenotype.
Neurology 2008;70(16 Pt 2):1491-3.
2008: Paula I Moreira; Akihiko Nunomura; Masao Nakamura; Atsushi Takeda; Justin Shenk; Gjumrakch Aliev; Mark A. Smith; George Perry
Nucleic acid oxidation in Alzheimer disease.
Free radical biology & medicine 2008;44(8):1493-505.
2007: Takafumi Hasegawa; Naoto Sugeno; Atsushi Takeda; Michiko Matsuzaki-Kobayashi; Akio Kikuchi; Katsutoshi Furukawa; Taeko Miyagi; Yasuto Itoyama
Role of Neu4L sialidase and its substrate ganglioside GD3 in neuronal apoptosis induced by catechol metabolites.
FEBS letters 2007;581(3):406-12.
2007: Akihiko Nunomura; Paula I Moreira; Atsushi Takeda; Mark A. Smith; George Perry
Oxidative RNA damage and neurodegeneration.
Current medicinal chemistry 2007;14(28):2968-75.
2006: K Jin; Atsushi Takeda; Y Shiga; S Sato; A Ohnuma; H Nomura; Hiroyuki Arai; S Kusunoki; M Ikeda; Y Itoyama
CSF tau protein: a new prognostic marker for Guillain-Barré syndrome.
Neurology 2006;67(8):1470-2.
2006: Hyoung-gon Lee; Xiongwei Zhu; Atsushi Takeda; George Perry; Mark A. Smith
Emerging evidence for the neuroprotective role of alpha-synuclein.
Experimental neurology 2006;200(1):1-7.
2006: Katsutoshi Furukawa; Michiko Matsuzaki-Kobayashi; Takafumi Hasegawa; Akio Kikuchi; Naoto Sugeno; Yasuto Itoyama; Yue Wang; Pamela J Yao; Ittai Bushlin; Atsushi Takeda
Plasma membrane ion permeability induced by mutant alpha-synuclein contributes to the degeneration of neural cells.
Journal of neurochemistry 2006;97(4):1071-7.
2006: Takafumi Hasegawa; Michiko Matsuzaki-Kobayashi; Atsushi Takeda; Naoto Sugeno; Akio Kikuchi; Katsutoshi Furukawa; George Perry; Mark A. Smith; Yasuto Itoyama
Alpha-synuclein facilitates the toxicity of oxidized catechol metabolites: implications for selective neurodegeneration in Parkinson's disease.
FEBS letters 2006;580(8):2147-52.
2006: Akihiko Nunomura; Kazuhiro Honda; Atsushi Takeda; Keisuke Hirai; Xiongwei Zhu; Mark A. Smith; George Perry
Oxidative damage to RNA in neurodegenerative diseases.
Journal of biomedicine & biotechnology 2006;2006(3):82323.
2006: Atsushi Takeda; Takafumi Hasegawa; Michiko Matsuzaki-Kobayashi; Naoto Sugeno; Akio Kikuchi; Yasuto Itoyama; Katsutoshi Furukawa
Mechanisms of neuronal death in synucleinopathy.
Journal of biomedicine & biotechnology 2006;2006(3):19365.
2005: Takafumi Hasegawa; Yusei Shiga; Koichi Narikawa; Kazutaka Jin; Kanae Fujihara; Atsushi Takeda; Yasuto Itoyama
Periodic episodes of aphasia as an unusual manifestation of partial status epilepticus.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2005;12(7):820-2.
2005: Takafumi Hasegawa; Naoto Sugeno; Yusei Shiga; Atsushi Takeda; Hiroshi Karibe; Teiji Tominaga; Yasuto Itoyama
Transethmoidal intranasal meningoencephalocele in an adult with recurrent meningitis.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2005;12(6):702-4.
2005: Barney E Dwyer; Atsushi Takeda; Xiongwei Zhu; George Perry; Mark A. Smith
Ferric cycle activity and Alzheimer disease.
Current neurovascular research 2005;2(3):261-7.
2005: Hyoung-gon Lee; George Perry; Paula I Moreira; Matthew R Garrett; Quan Liu; Xiongwei Zhu; Atsushi Takeda; Akihiko Nunomura; Mark A. Smith
Tau phosphorylation in Alzheimer's disease: pathogen or protector?
Trends in molecular medicine 2005;11(4):164-9.
2005: Quan Liu; Mark A. Smith; Jesús Avila; John DeBernardis; Mayank M Kansal; Atsushi Takeda; Xiongwei Zhu; Akihiko Nunomura; Kazuhiro Honda; Paula I Moreira; Catarina R Oliveira; Maria S Santos; Shun Shimohama; Gjumrakch Aliev; Jack C. de la Torre; Hossein A Ghanbari; Sandra L Siedlak; Peggy L R Harris; Lawrence M Sayre; George Perry
Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations.
Free radical biology & medicine 2005;38(6):746-54.
2005: Quan Liu; Hyoung-gon Lee; Kazuhiro Honda; Sandra L Siedlak; Peggy L R Harris; Adam D Cash; Xiongwei Zhu; Jesús Avila; Akihiko Nunomura; Atsushi Takeda; Mark A. Smith; George Perry
Tau modifiers as therapeutic targets for Alzheimer's disease.
Biochimica et biophysica acta 2005;1739(2-3):211-5.
2004: Akihiko Nunomura; Shigeru Chiba; Carol F Lippa; Patrick Cras; Rajesh N. Kalaria; Atsushi Takeda; Kazuhiro Honda; Mark A. Smith; George Perry
Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease.
Neurobiology of disease 2004;17(1):108-13.
2004: Atsushi Takeda; Yasuto Itoyama; Teiko Kimpara; Xiongwei Zhu; Jesús Avila; Barney E Dwyer; George Perry; Mark A. Smith
Heme catabolism and heme oxygenase in neurodegenerative disease.
Antioxidants & redox signaling 2004;6(5):888-94.
2004: Takafumi Hasegawa; Michiko Matsuzaki; Atsushi Takeda; Akio Kikuchi; Hirotoshi Akita; George Perry; Mark A. Smith; Yasuto Itoyama
Accelerated alpha-synuclein aggregation after differentiation of SH-SY5Y neuroblastoma cells.
Brain research 2004;1013(1):51-9.
2004: Hyoung-gon Lee; Gemma Casadesus Smith; Xiongwei Zhu; Atsushi Takeda; George Perry; Mark A. Smith
Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease.
Annals of the New York Academy of Sciences 2004;1019():1-4.
2004: Juan Feng; Tatsuro Misu; Kazuo Fujihara; Naoko Misawa; Yoshio Koyanagi; Yusei Shiga; Atsushi Takeda; Shigeru Sato; Sadao Takase; Takeshi Kohnosu; Hiroshi Saito; Yasuto Itoyama
Th1/Th2 balance and HTLV-I proviral load in HAM/TSP patients treated with interferon-alpha.
Journal of neuroimmunology 2004;151(1-2):189-94.
2004: Akio Kikuchi; Atsushi Takeda; Kazuo Fujihara; Teiko Kimpara; Yusei Shiga; Hiroaki Tanji; Makiko Nagai; Hiroshi Ichinose; Fumi Urano; Nobuyuki Okamura; Hiroyuki Arai; Yasuto Itoyama
Arg(184)His mutant GTP cyclohydrolase I, causing recessive hyperphenylalaninemia, is responsible for dopa-responsive dystonia with parkinsonism: a case report.
Movement disorders : official journal of the Movement Disorder Society 2004;19(5):590-3.
2004: Michiko Matsuzaki; Takafumi Hasegawa; Atsushi Takeda; Akio Kikuchi; Katsutoshi Furukawa; Yoji Kato; Yasuto Itoyama
Histochemical features of stress-induced aggregates in alpha-synuclein overexpressing cells.
Brain research 2004;1004(1-2):83-90.
2003: Yusei Shiga; Koichi Miyazawa; Atsushi Takeda; Hiroyuki Arai; Katsumi Doh-ura; Yasuto Itoyama
[Laboratory and imaging studies for the diagnosis of prion disease].
Rinshō shinkeigaku = Clinical neurology 2003;43(11):810-2.
2003: Maki Tateyama; Naohiro Saito; Kazuo Fujihara; Yusei Shiga; Atsushi Takeda; Koichi Narikawa; Takafumi Hasegawa; Yuzuru Taguchi; Ryo Sakuma; Yoshiaki Onodera; Ayumu Ohnuma; Muneshige Tobita; Yasuto Itoyama
Familial inclusion body myositis: a report on two Japanese sisters.
Internal medicine (Tokyo, Japan) 2003;42(10):1035-8.
2003: Takafumi Hasegawa; Michiko Matsuzaki; Atsushi Takeda; Akio Kikuchi; Katsutoshi Furukawa; Shigeki Shibahara; Yasuto Itoyama
Increased dopamine and its metabolites in SH-SY5Y neuroblastoma cells that express tyrosinase.
Journal of neurochemistry 2003;87(2):470-5.
2003: Juan Feng; Tatsuro Misu; Kazuo Fujihara; Hiroshi Saito; Toshiaki Takahashi; Takeshi Kohnosu; Yusei Shiga; Atsushi Takeda; Shigeru Sato; Sadao Takase; Yasuto Itoyama
Interferon-alpha significantly reduces cerebrospinal fluid CD4 cell subsets in HAM/TSP.
Journal of neuroimmunology 2003;141(1-2):170-3.
2003: Toshihiro Masaki; Sachio Matsushita; Hiroyuki Arai; Atsushi Takeda; Yasuto Itoyama; Hitoshi Mochizuki; Keiko Kamakura; Shinji Ohara; Susumu Higuchi
Association between a polymorphism of brain-derived neurotrophic factor gene and sporadic Parkinson's disease.
Annals of neurology 2003;54(2):276-7.
2003: Makoto Watanabe; Takafumi Hasegawa; Atsushi Takeda; Yusei Shiga; Yasuto Itoyama
[A case of hypokalemic periodic paralysis: utility of exercise test for the assessment of therapeutic efficacy].
Nō to shinkei = Brain and nerve 2003;55(6):527-9.
2003: Maki Tateyama; Atsushi Takeda; Yoshiaki Onodera; M Matsuzaki; Takafumi Hasegawa; Akihiko Nunomura; K Hirai; George Perry; Mark A. Smith; Yasuto Itoyama
Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles.
Acta neuropathologica 2003;105(6):581-5.
2002: Takafumi Hasegawa; Yuusei Shiga; Arifumi Matsumoto; Atsushi Takeda; Yasuto Itoyama
[Late-onset nonketotic hyperglycinemia: a case report].
Nō to shinkei = Brain and nerve 2002;54(12):1068-72.
2002: George Perry; Akihiko Nunomura; Keisuke Hirai; Xiongwei Zhu; Mar Pérez; Jesús Avila; Rudy J Castellani; Craig S Atwood; Gjumrakch Aliev; Lawrence M Sayre; Atsushi Takeda; Mark A. Smith
Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?
Free radical biology & medicine 2002;33(11):1475-9.
2002: Akihiko Nunomura; Shigeru Chiba; Kenji Kosaka; Atsushi Takeda; Rudy J Castellani; Mark A. Smith; George Perry
Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies.
Neuroreport 2002;13(16):2035-9.
2002: Rudy J Castellani; Keisuke Hirai; Gjumrakch Aliev; Kelly L Drew; Akihiko Nunomura; Atsushi Takeda; Adam D Cash; Mark E Obrenovich; George Perry; Mark A. Smith
Role of mitochondrial dysfunction in Alzheimer's disease.
Journal of neuroscience research 2002;70(3):357-60.
2002: Mark A. Smith; Kelly L Drew; Akihiko Nunomura; Atsushi Takeda; Keisuke Hirai; Xiongwei Zhu; Craig S Atwood; Arun K Raina; Catherine A Rottkamp; Lawrence M Sayre; Robert P Friedland; George Perry
Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs?
Neurochemistry international 2002;40(6):527-31.
2002: Akio Kikuchi; Atsushi Takeda; Hiroshi Onodera; Teiko Kimpara; Kinya Hisanaga; Nobuyuki Sato; Akihiko Nunomura; Rudy J Castellani; George Perry; Mark A. Smith; Yasuto Itoyama
Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy.
Neurobiology of disease 2002;9(2):244-8.
2001: Akio Kikuchi; Atsushi Takeda; Teiko Kimpara; M Nakagawa; R Kawashima; M Sugiura; S Kinomura; H Fukuda; K Chida; Naoshi Okita; Sadao Takase; Yasuto Itoyama
Hypoperfusion in the supplementary motor area, dorsolateral prefrontal cortex and insular cortex in Parkinson's disease.
Journal of the neurological sciences 2001;193(1):29-36.
2001: Xiongwei Zhu; Rudy J Castellani; Atsushi Takeda; Akihiko Nunomura; Craig S Atwood; George Perry; Mark A. Smith
Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis.
Mechanisms of ageing and development 2001;123(1):39-46.
2001: Koichi Narikawa; Takafumi Hasegawa; Atsushi Takeda; Yusei Shiga; Yasuto Itoyama
[Successful treatment of emotional disturbances following non-herpetic limbic encephalitis by serotonergic agents. A case report].
Rinshō shinkeigaku = Clinical neurology 2001;41(11):805-8.
2001: Xiongwei Zhu; Catherine A Rottkamp; Anthony W Hartzler; Zheng Sun; Atsushi Takeda; H Boux; Shun Shimohama; George Perry; Mark A. Smith
Activation of MKK6, an upstream activator of p38, in Alzheimer's disease.
Journal of neurochemistry 2001;79(2):311-8.
2001: Akihiko Nunomura; George Perry; Gjumrakch Aliev; Keisuke Hirai; Atsushi Takeda; Elizabeth Balraj; Paul K Jones; Hossein A Ghanbari; Takafumi Wataya; Shun Shimohama; S Chiba; Craig S Atwood; Robert B Petersen; Mark A. Smith
Oxidative damage is the earliest event in Alzheimer disease.
Journal of neuropathology and experimental neurology 2001;60(8):759-67.
2001: A Kikuchi; Yusei Shiga; J Onodera; Atsushi Takeda; Yasuto Itoyama
[A case of Tolosa-Hunt syndrome starting from abducens nerve palsy alone].
Rinshō shinkeigaku = Clinical neurology 2001;41(6):296-8.
2001: T Endo; Atsushi Takeda; Y Shiga; J Fujimori; T Takahashi; M Tateyama; H Onodera; Y Itoyama; T Yoshimoto
[A case of potassium-sensitive periodic paralysis with cardiac dysrhythmia controlled with imipramine and acetazolamide].
Nō to shinkei = Brain and nerve 2001;53(4):373-6.
2001: Nobuyuki Okamura; Hiroyuki Arai; Makoto Higuchi; M Tashiro; Toshifumi Matsui; X S Hu; Atsushi Takeda; M Itoh; Hidetada Sasaki
[18F]FDG-PET study in dementia with Lewy bodies and Alzheimer's disease.
Progress in neuro-psychopharmacology & biological psychiatry 2001;25(2):447-56.
2001: M Kimura; S Matsushita; Hiroyuki Arai; Atsushi Takeda; S Higuchi
No evidence of association between a dopamine transporter gene polymorphism (1215A/G) and Parkinson's disease.
Annals of neurology 2001;49(2):276-7.
2000: A Kanda; S Ebihara; Heii Arai; Atsushi Takeda; Hidetada Sasaki
Parkinson's disease and impaired chemosensitivity to hypoxia.
Lancet 2000;356(9247):2100.
2000: Xiongwei Zhu; Catherine A Rottkamp; H Boux; Atsushi Takeda; George Perry; Mark A. Smith
Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease.
Journal of neuropathology and experimental neurology 2000;59(10):880-8.
2000: Maki Tateyama; Muneshige Tobita; Atsushi Takeda; K Chida; Yoshiaki Onodera; A Kikuchi; N Aoyagi; Yasuto Itoyama
DNA single-strand breaks are increased in muscle diseases with rimmed vacuoles.
Acta neuropathologica 2000;100(4):390-4.
2000: Atsushi Takeda; Mark A. Smith; Jesús Avila; Akihiko Nunomura; Sandra L Siedlak; Xiongwei Zhu; George Perry; Lawrence M Sayre
In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification.
Journal of neurochemistry 2000;75(3):1234-41.
2000: K Yamakawa; H Kuroda; K Fujihara; S Sato; Ichiro Nakashima; Atsushi Takeda; K Suzuki; Y Itoyama
Familial neuromyelitis optica (Devic's syndrome) with late onset in Japan.
Neurology 2000;55(2):318-20.
2000: Arun K Raina; Xiongwei Zhu; Catherine A Rottkamp; Mervyn Monteiro; Atsushi Takeda; Mark A. Smith
Cyclin' toward dementia: cell cycle abnormalities and abortive oncogenesis in Alzheimer disease.
Journal of neuroscience research 2000;61(2):128-33.
2000: K Iwasaki; Q Wang; H Seki; K Satoh; Atsushi Takeda; Hiroyuki Arai; Hidetada Sasaki
The effects of the traditional chinese medicine, "Banxia Houpo Tang (Hange-Koboku To)" on the swallowing reflex in Parkinson's disease.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2000;7(4):259-63.
2000: Teiko Kimpara; Atsushi Takeda; T Yamaguchi; Hiroyuki Arai; Naoshi Okita; Sadao Takase; Hidetada Sasaki; Yasuto Itoyama
Increased bilirubins and their derivatives in cerebrospinal fluid in Alzheimer's disease.
Neurobiology of aging 2000;21(4):551-4.
2000: Xiongwei Zhu; Arun K Raina; H Boux; Z L Simmons; Atsushi Takeda; Mark A. Smith
Activation of oncogenic pathways in degenerating neurons in Alzheimer disease.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2000;18(4-5):433-7.
2000: George Perry; Akihiko Nunomura; K Hirai; Atsushi Takeda; Gjumrakch Aliev; Mark A. Smith
Oxidative damage in Alzheimer's disease: the metabolic dimension.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2000;18(4-5):417-21.
2000: JL Gerst; Arun K Raina; I Pirim; Andy McShea; Peggy L R Harris; Sandra L Siedlak; Atsushi Takeda; Robert B Petersen; Mark A. Smith
Altered cell-matrix associated ADAM proteins in Alzheimer disease.
Journal of neuroscience research 2000;59(5):680-4.
2000: Atsushi Takeda; George Perry; N G Abraham; Barney E Dwyer; R K Kutty; J T Laitinen; Robert B Petersen; Mark A. Smith
Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau.
The Journal of biological chemistry 2000;275(8):5395-9.
2000: Mark A. Smith; Akihiko Nunomura; Xiongwei Zhu; Atsushi Takeda; George Perry
Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease.
Antioxidants & redox signaling 2000;2(3):413-20.
2000: Arun K Raina; Xiongwei Zhu; Mervyn Monteiro; Atsushi Takeda; Mark A. Smith
Abortive oncogeny and cell cycle-mediated events in Alzheimer disease.
Progress in cell cycle research 2000;4():235-42.
2000: A Kikuchi; K Chida; Tatsuro Misu; Naoshi Okita; H Nomura; H Konno; S Takase; Atsushi Takeda; Yasuto Itoyama
[A case of Wernicke-Korsakoff syndrome with dramatic improvement in consciousness immediately after intravenous infusion of thiamine].
Nō to shinkei = Brain and nerve 2000;52(1):59-63.
1999: Arun K Raina; Atsushi Takeda; Mark A. Smith
Mitotic neurons: a dogma succumbs.
Experimental neurology 1999;159(1):248-9.
1999: Norihiro Yamada; Mutsuo Yamaya; Shoji Okinaga; R Lie; Tomoko Suzuki; Katsutoshi Nakayama; Atsushi Takeda; T Yamaguchi; Y Itoyama; Kiyohisa Sekizawa; Hidetada Sasaki
Protective effects of heme oxygenase-1 against oxidant-induced injury in the cultured human tracheal epithelium.
American journal of respiratory cell and molecular biology 1999;21(3):428-35.
1999: George Perry; H Roder; Akihiko Nunomura; Atsushi Takeda; Avi Friedlich; Xiongwei Zhu; Arun K Raina; N Holbrook; Sandra L Siedlak; P L Harris; Mark A. Smith
Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation.
Neuroreport 1999;10(11):2411-5.
1999: Mark A. Smith; Akihiko Nunomura; Atsushi Takeda; George Perry
Asking the right questions.
Science (New York, N.Y.) 1999;285(5428):665.
1999: Arun K Raina; Atsushi Takeda; Akihiko Nunomura; George Perry; Mark A. Smith
Genetic evidence for oxidative stress in Alzheimer's disease.
Neuroreport 1999;10(6):1355-7.
1999: Akihiko Nunomura; George Perry; K Hirai; Gjumrakch Aliev; Atsushi Takeda; S Chiba; Mark A. Smith
Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
Annals of the New York Academy of Sciences 1999;893():362-4.
1998: Teiko Kimpara; Atsushi Takeda; Naoshi Okita; Sadao Takase; H Saito; Yasuto Itoyama
The familial parkinsonism locus on chromosome 4 and idiopathic Parkinson's disease in Japan.
Journal of neurology, neurosurgery, and psychiatry 1998;64(3):416-7.
1998: R Mochizuki; Atsushi Takeda; N Sato; Teiko Kimpara; Hiroshi Onodera; Yasuto Itoyama; T Muramatsu
Induction of midkine expression in reactive astrocytes following rat transient forebrain ischemia.
Experimental neurology 1998;149(1):73-8.
1997: Teiko Kimpara; Atsushi Takeda; K Watanabe; Yasuto Itoyama; S Ikawa; M Watanabe; Hiroyuki Arai; Hidetada Sasaki; S Higuchi; Naoshi Okita; Sadao Takase; Hiroshi Saito; K Takahashi; S Shibahara
Microsatellite polymorphism in the human heme oxygenase-1 gene promoter and its application in association studies with Alzheimer and Parkinson disease.
Human genetics 1997;100(1):145-7.
1996: Y L Huang; Hiroshi Onodera; Atsushi Takeda; Yasuto Itoyama; K Kogure
The effect of long-term post-ischemic bifemelane hydrochloride treatment on cholinergic systems in the gerbil hippocampus.
Brain research 1996;722(1-2):195-9.
1996: Atsushi Takeda; Teiko Kimpara; Hiroshi Onodera; Yasuto Itoyama; S Shibahara; K Kogure
Regional difference in induction of heme oxygenase-1 protein following rat transient forebrain ischemia.
Neuroscience letters 1996;205(3):169-72.
1994: Atsushi Takeda; Hiroshi Onodera; A Sugimoto; Yasuto Itoyama; K Kogure; S Shibahara
Increased expression of heme oxygenase mRNA in rat brain following transient forebrain ischemia.
Brain research 1994;666(1):120-4.
1994: A Sugimoto; Atsushi Takeda; K Kogure; Hiroshi Onodera
NMDA receptor (NMDAR1) expression in the rat hippocampus after forebrain ischemia.
Neuroscience letters 1994;170(1):39-42.
1993: Atsushi Takeda; H Onodera; A Sugimoto; K Kogure; M Obinata; S Shibahara
Coordinated expression of messenger RNAs for nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 in the rat hippocampus following transient forebrain ischemia.
Neuroscience 1993;55(1):23-31.
1992: J Matsunaga; Atsushi Takeda; Y Tomita; M Hara; S Shibahara; Hachiro Tagami
Cloning and sequence analysis of the tyrosinase gene from a patient with tyrosinase-positive oculocutaneous albinism.
Journal of dermatological science 1992;3(3):181-5.
1992: Atsushi Takeda; H Onodera; Y Yamasaki; K Furukawa; K Kogure; M Obinata; S Shibahara
Decreased expression of neurotrophin-3 mRNA in the rat hippocampus following transient forebrain ischemia.
Brain research 1992;569(1):177-80.
1992: Y Tomita; Atsushi Takeda; J Matsunaga; S Okinaga; S Shibahara; H Tagami
Molecular bases of tyrosinase-negative oculocutaneous albinism: a single base insertion or a missense point mutation in the tyrosinase gene.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1992;Suppl 2():96-100.
1991: Atsushi Takeda; J Matsunaga; Y Tomita; H Tagami; Shigeki Shibahara
Nucleotide sequence of the putative human tyrosinase pseudogene.
The Tohoku journal of experimental medicine 1991;163(4):295-7.
1991: Y Tomita; S Shibahara; Atsushi Takeda; S Okinaga; J Matsunaga; Hachiro Tagami
The monoclonal antibodies TMH-1 and TMH-2 specifically bind to a protein encoded at the murine b-locus, not to the authentic tyrosinase encoded at the c-locus.
The Journal of investigative dermatology 1991;96(4):500-4.
1990: Atsushi Takeda; Y Tomita; J Matsunaga; H Tagami; S Shibahara
Molecular basis of tyrosinase-negative oculocutaneous albinism. A single base mutation in the tyrosinase gene causing arginine to glutamine substitution at position 59.
The Journal of biological chemistry 1990;265(29):17792-7.
1990: S Shibahara; S Okinaga; Y Tomita; Atsushi Takeda; H Yamamoto; M Sato; T Takeuchi
A point mutation in the tyrosinase gene of BALB/c albino mouse causing the cysteine----serine substitution at position 85.
European journal of biochemistry / FEBS 1990;189(2):455-61.
1989: Atsushi Takeda; J Matsunaga; Y Tomita; H Tagami; S Shibahara
Molecular analysis of the DNA segments cross-hybridizable to the tyrosinase gene in patients affected with oculocutaneous albinism.
The Tohoku journal of experimental medicine 1989;159(4):333-40.
1989: Y Tomita; Atsushi Takeda; S Okinaga; H Tagami; S Shibahara
Human oculocutaneous albinism caused by single base insertion in the tyrosinase gene.
Biochemical and biophysical research communications 1989;164(3):990-6.
1989: Atsushi Takeda; Y Tomita; S Okinaga; H Tagami; S Shibahara
Functional analysis of the cDNA encoding human tyrosinase precursor.
Biochemical and biophysical research communications 1989;162(3):984-90.