Gary Hammer

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Strosberg Jonathan R; Hammer Gary D; Doherty Gerard M
Management of adrenocortical carcinoma.
Else Tobias; Trovato Alessia; Kim Alex C; Wu Yipin; Ferguson David O; Kuick Rork D; Lucas Peter C; Hammer Gary D
Genetic p53 deficiency partially rescues the adrenocortical dysplasia phenotype at the expense of increased tumorigenesis.
Kim A; Giordano T-J; Kuick R; Serecky K; Hammer G D
Wnt/betacatenin signaling in adrenocortical stem/progenitor cells: implications for adrenocortical carcinoma.

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All Publications

2009: Strosberg Jonathan R; Hammer Gary D; Doherty Gerard M
Management of adrenocortical carcinoma.
Journal of the National Comprehensive Cancer Network : JNCCN 2009;7(7):752-8; quiz 759.
2009: Else Tobias; Trovato Alessia; Kim Alex C; Wu Yipin; Ferguson David O; Kuick Rork D; Lucas Peter C; Hammer Gary D
Genetic p53 deficiency partially rescues the adrenocortical dysplasia phenotype at the expense of increased tumorigenesis.
Cancer cell 2009;15(6):465-76.
2009: Kim A; Giordano T-J; Kuick R; Serecky K; Hammer G D
Wnt/betacatenin signaling in adrenocortical stem/progenitor cells: implications for adrenocortical carcinoma.
Annales d'endocrinologie 2009;70(3):156.
2009: Kim Alex C; Barlaskar Ferdous M; Heaton Joanne H; Else Tobias; Kelly Victoria R; Krill Kenneth T; Scheys Joshua O; Simon Derek P; Trovato Alessia; Yang Wei-Hsiung; Hammer Gary D
In search of adrenocortical stem and progenitor cells.
Endocrine reviews 2009;30(3):241-63.
2009: Xu Bin; Yang Wei-Hsiung; Gerin Isabelle; Hu Chang-Deng; Hammer Gary D; Koenig Ronald J
Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis.
Molecular and cellular biology 2009;29(7):1719-34.
2009: Yang Wei-Hsiung; Heaton Joanne H; Brevig Holly; Mukherjee Sarmistha; Iñiguez-Lluhí Jorge A; Hammer Gary D
SUMOylation inhibits SF-1 activity by reducing CDK7-mediated serine 203 phosphorylation.
Molecular and cellular biology 2009;29(3):613-25.
2009: Giordano Thomas J; Kuick Rork; Else Tobias; Gauger Paul G; Vinco Michelle; Bauersfeld Juliane; Sanders Donita; Thomas Dafydd G; Doherty Gerard; Hammer Gary
Molecular classification and prognostication of adrenocortical tumors by transcriptome profiling.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(2):668-76.
2009: Barlaskar Ferdous M; Spalding Aaron C; Heaton Joanne H; Kuick Rork; Kim Alex C; Thomas Dafydd G; Giordano Thomas J; Ben-Josef Edgar; Hammer Gary D
Preclinical targeting of the type I insulin-like growth factor receptor in adrenocortical carcinoma.
The Journal of clinical endocrinology and metabolism 2009;94(1):204-12.
2008: White Matthew L; Gauger Paul G; Doherty Gerard M; Cho Kyung J; Thompson Norman W; Hammer Gary D; Miller Barbra S
The role of radiologic studies in the evaluation and management of primary hyperaldosteronism.
Surgery 2008;144(6):926-33; discussion 933.
2008: Kim Alex C; Reuter Anne L; Zubair Mohamad; Else Tobias; Serecky Kerri; Bingham Nathan C; Lavery Gareth G; Parker Keith L; Hammer Gary D
Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex.
Development (Cambridge, England) 2008;135(15):2593-602.
2008: Rui Xianliang; Tsao Jennivine; Scheys Joshua O; Hammer Gary D; Schimmer Bernard P
Contributions of specificity protein-1 and steroidogenic factor 1 to Adcy4 expression in Y1 mouse adrenal cells.
Endocrinology 2008;149(7):3668-78.
2008: Else Tobias; Giordano Thomas J; Hammer Gary D
Evaluation of telomere length maintenance mechanisms in adrenocortical carcinoma.
The Journal of clinical endocrinology and metabolism 2008;93(4):1442-9.
2007: Barlaskar Ferdous M; Hammer Gary D
The molecular genetics of adrenocortical carcinoma.
Reviews in endocrine & metabolic disorders 2007;8(4):343-8.
2007: Looyenga Brendan D; Hammer Gary D
Genetic removal of Smad3 from inhibin-null mice attenuates tumor progression by uncoupling extracellular mitogenic signals from the cell cycle machinery.
Molecular endocrinology (Baltimore, Md.) 2007;21(10):2440-57.
2007: Hockemeyer Dirk; Palm Wilhelm; Else Tobias; Daniels Jan-Peter; Takai Kaori K; Ye Jeffrey Z-S; Keegan Catherine E; de Lange Titia; Hammer Gary D
Telomere protection by mammalian Pot1 requires interaction with Tpp1.
Nature structural & molecular biology 2007;14(8):754-61.
2007: Keegan Catherine E; Hutz Janna E; Krause Andrea S; Koehler Katrin; Metherell Louise A; Boikos Sosipatros; Stergiopoulos Sotirios; Clark Adrian J L; Stratakis Constantine A; Huebner Angela; Hammer Gary D
Novel polymorphisms and lack of mutations in the ACD gene in patients with ACTH resistance syndromes.
Clinical endocrinology 2007;67(2):168-74.
2007: Kim Alex C; Hammer Gary D
Adrenocortical cells with stem/progenitor cell properties: recent advances.
Molecular and cellular endocrinology 2007;265-266():10-6.
2007: Lichtenauer Urs D; Duchniewicz Marlena; Kolanczyk Mateusz; Hoeflich Andreas; Hahner Stephanie; Else Tobias; Bicknell Andrew B; Zemojtel Tomasz; Stallings Nancy R; Schulte Dominik M; Kamps Mark P; Hammer Gary D; Scheele Jürgen S; Beuschlein Felix
Pre-B-cell transcription factor 1 and steroidogenic factor 1 synergistically regulate adrenocortical growth and steroidogenesis.
Endocrinology 2007;148(2):693-704.
2007: Else Tobias; Theisen Brian K; Wu Yipin; Hutz Janna E; Keegan Catherine E; Hammer Gary D; Ferguson David O
Tpp1/Acd maintains genomic stability through a complex role in telomere protection.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2007;15(8):1001-13.
2006: Looyenga Brendan D; Hammer Gary D
Origin and identity of adrenocortical tumors in inhibin knockout mice: implications for cellular plasticity in the adrenal cortex.
Molecular endocrinology (Baltimore, Md.) 2006;20(11):2848-63.
2006: Gummow Brian M; Scheys Joshua O; Cancelli Victoria R; Hammer Gary D
Reciprocal regulation of a glucocorticoid receptor-steroidogenic factor-1 transcription complex on the Dax-1 promoter by glucocorticoids and adrenocorticotropic hormone in the adrenal cortex.
Molecular endocrinology (Baltimore, Md.) 2006;20(11):2711-23.
2006: Johnsen Inga K; Slawik Marc; Shapiro Igor; Hartmann Michaela F; Wudy Stefan A; Looyenga Brendan D; Hammer Gary D; Reincke Martin; Beuschlein Felix
Gonadectomy in mice of the inbred strain CE/J induces proliferation of sub-capsular adrenal cells expressing gonadal marker genes.
The Journal of endocrinology 2006;190(1):47-57.
2006: Hutz Janna E; Krause Andrea S; Achermann John C; Vilain Eric; Tauber Maïthé; Lecointre Claudine; McCabe Edward R B; Hammer Gary D; Keegan Catherine E
IMAGe association and congenital adrenal hypoplasia: no disease-causing mutations found in the ACD gene.
Molecular genetics and metabolism 2006;88(1):66-70.
2006: Winnay Jonathon N; Xu Jianming; O'Malley Bert W; Hammer Gary D
Steroid receptor coactivator-1-deficient mice exhibit altered hypothalamic-pituitary-adrenal axis function.
Endocrinology 2006;147(3):1322-32.
2006: Winnay Jonathon N; Hammer Gary D
Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation.
Molecular endocrinology (Baltimore, Md.) 2006;20(1):147-66.
2005: Else Tobias; Hammer Gary D
Genetic analysis of adrenal absence: agenesis and aplasia.
Trends in endocrinology and metabolism: TEM 2005;16(10):458-68.
2005: Schteingart D E; Doherty G M; Gauger P G; Giordano T J; Hammer G D; Korobkin M; Worden F P
Management of patients with adrenal cancer: recommendations of an international consensus conference.
Endocrine-related cancer 2005;12(3):667-80.
2005: Park Susan Y; Meeks Joshua J; Raverot Gerald; Pfaff Liza E; Weiss Jeffrey; Hammer Gary D; Jameson J Larry
Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development.
Development (Cambridge, England) 2005;132(10):2415-23.
2005: Hammer Gary D; Parker Keith L; Schimmer Bernard P
Minireview: transcriptional regulation of adrenocortical development.
Endocrinology 2005;146(3):1018-24.
2005: Keegan Catherine E; Hutz Janna E; Else Tobias; Adamska Maja; Shah Sonalee P; Kent Amy E; Howes John M; Beamer Wesley G; Hammer Gary D
Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator.
Human molecular genetics 2005;14(1):113-23.
2004: Hammer Gary D; Tyrrell J Blake; Lamborn Kathleen R; Applebury Carol B; Hannegan Elizabeth T; Bell Scott; Rahl Riva; Lu Amy; Wilson Charles B
Transsphenoidal microsurgery for Cushing's disease: initial outcome and long-term results.
The Journal of clinical endocrinology and metabolism 2004;89(12):6348-57.
2004: Looyenga Brendan; Beuschlein Felix; Nilson John; Hammer Gary D
Mechanistic roles of inhibin as a tumor suppressor in the adrenal cortex.
Endocrine research 2004;30(4):585-6.
2004: Beuschlein F; Looyenga B D; Reincke M; Hammer G D
Role of the inhibin/activin system and luteinizing hormone in adrenocortical tumorigenesis.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(6):392-6.
2003: Kennell Jennifer A; O'Leary Erin E; Gummow Brian M; Hammer Gary D; MacDougald Ormond A
T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors.
Molecular and cellular biology 2003;23(15):5366-75.
2003: Gummow Brian M; Winnay Jonathon N; Hammer Gary D
Convergence of Wnt signaling and steroidogenic factor-1 (SF-1) on transcription of the rat inhibin alpha gene.
The Journal of biological chemistry 2003;278(29):26572-9.
2003: Beuschlein Felix; Looyenga Brendan D; Bleasdale Stephanie E; Mutch Chris; Bavers David L; Parlow Albert F; Nilson John H; Hammer Gary D
Activin induces x-zone apoptosis that inhibits luteinizing hormone-dependent adrenocortical tumor formation in inhibin-deficient mice.
Molecular and cellular biology 2003;23(11):3951-64.
2002: Beuschlein F; Keegan C E; Bavers D L; Mutch C; Hutz J E; Shah S; Ulrich-Lai Y M; Engeland W C; Jeffs B; Jameson J L; Hammer G D
SF-1, DAX-1, and acd: molecular determinants of adrenocortical growth and steroidogenesis.
Endocrine research 2002;28(4):597-607.
2002: Beuschlein Felix; Mutch Chris; Bavers David L; Ulrich-Lai Yvonne M; Engeland William C; Keegan Catherine; Hammer Gary D
Steroidogenic factor-1 is essential for compensatory adrenal growth following unilateral adrenalectomy.
Endocrinology 2002;143(8):3122-35.
2002: Keegan Catherine E; Hammer Gary D
Recent insights into organogenesis of the adrenal cortex.
Trends in endocrinology and metabolism: TEM 2002;13(5):200-8.
2002: Beuschlein Felix; Hammer Gary D
Ectopic pro-opiomelanocortin syndrome.
Endocrinology and metabolism clinics of North America 2002;31(1):191-234.
2002: Babu Poda Suresh; Bavers David L; Beuschlein Felix; Shah Sonalee; Jeffs Baxter; Jameson J Larry; Hammer Gary D
Interaction between Dax-1 and steroidogenic factor-1 in vivo: increased adrenal responsiveness to ACTH in the absence of Dax-1.
Endocrinology 2002;143(2):665-73.
2000: Babu P S; Bavers D L; Shah S; Hammer G D
Role of phosphorylation, gene dosage and Dax-1 in SF-1 mediated steroidogenesis.
Endocrine research 2000;26(4):985-94.
1999: Hammer G D; Ingraham H A
Steroidogenic factor-1: its role in endocrine organ development and differentiation.
Frontiers in neuroendocrinology 1999;20(3):199-223.
1999: Hammer G D; Krylova I; Zhang Y; Darimont B D; Simpson K; Weigel N L; Ingraham H A
Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress.
Molecular cell 1999;3(4):521-6.
1998: Nachtigal M W; Hirokawa Y; Enyeart-VanHouten D L; Flanagan J N; Hammer G D; Ingraham H A
Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression.
Cell 1998;93(3):445-54.
1993: Low M J; Liu B; Hammer G D; Rubinstein M; Allen R G
Post-translational processing of proopiomelanocortin (POMC) in mouse pituitary melanotroph tumors induced by a POMC-simian virus 40 large T antigen transgene.
The Journal of biological chemistry 1993;268(33):24967-75.
1992: Liu B; Hammer G D; Rubinstein M; Mortrud M; Low M J
Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice.
Molecular and cellular biology 1992;12(9):3978-90.
1992: Asa S L; Kovacs K; Hammer G D; Liu B; Roos B A; Low M J
Pituitary corticotroph hyperplasia in rats implanted with a medullary thyroid carcinoma cell line transfected with a corticotropin-releasing hormone complementary deoxyribonucleic acid expression vector.
Endocrinology 1992;131(2):715-20.
1992: Hammer G D; Mueller G; Liu B; Petrides J S; Roos B A; Low M J
Ectopic corticotropin-releasing hormone produced by a transfected cell line chronically activates the pituitary-adrenal axis in transkaryotic rats.
Endocrinology 1992;130(4):1975-85.
1990: Hammer G D; Fairchild-Huntress V; Low M J
Pituitary-specific and hormonally regulated gene expression directed by the rat proopiomelanocortin promoter in transgenic mice.
Molecular endocrinology (Baltimore, Md.) 1990;4(11):1689-97.
1986: Hammer G D; Kapp B S
The effects of naloxone administered into the periaqueductal gray on shock-elicited freezing behavior in the rat.
Behavioral and neural biology 1986;46(2):189-95.

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Gary Hammer

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