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Dai stephens

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Y Peña-Oliver; Tamzin L Ripley; Trevor W Robbins; G Schumann; V L Buchman; J W Dalley; S L King; Dai stephens
Deletion of alpha-synuclein decreases impulsivity in mice.
Eoin C O'Connor; Hans S Crombag; Andy N Mead; Dai stephens
The mGluR5 antagonist MTEP dissociates the acquisition of predictive and incentive motivational properties of reward-paired stimuli in mice.
Claire I Dixon; Hannah V Morris; Gerome Breen; Sylvane Desrivieres; Sarah Jugurnauth; Rebecca C Steiner; Homero Vallada; Camila Guindalini; ronaldo laranjeira; Guilherme Messas; Thomas W Rosahl; John R Atack; Dianne R Peden; Delia Belelli; Jeremy J Lambert; Sarah L King; Gunter Schumann; Dai stephens
Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors.

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2012: Y Peña-Oliver; Tamzin L Ripley; Trevor W Robbins; G Schumann; V L Buchman; J W Dalley; S L King; Dai stephens
Deletion of alpha-synuclein decreases impulsivity in mice.
Genes, brain, and behavior 2012;11(2):137-46.
2010: Eoin C O'Connor; Hans S Crombag; Andy N Mead; Dai stephens
The mGluR5 antagonist MTEP dissociates the acquisition of predictive and incentive motivational properties of reward-paired stimuli in mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(8):1807-17.
2010: Claire I Dixon; Hannah V Morris; Gerome Breen; Sylvane Desrivieres; Sarah Jugurnauth; Rebecca C Steiner; Homero Vallada; Camila Guindalini; ronaldo laranjeira; Guilherme Messas; Thomas W Rosahl; John R Atack; Dianne R Peden; Delia Belelli; Jeremy J Lambert; Sarah L King; Gunter Schumann; Dai stephens
Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(5):2289-94.
2009: Yolanda Peña Oliver; Tamzin L Ripley; Dai stephens
Ethanol effects on impulsivity in two mouse strains: similarities to diazepam and ketamine.
Psychopharmacology 2009;204(4):679-92.
2009: H V Morris; S Nilsson; C I Dixon; Dai stephens; Peter G Clifton
Alpha1- and alpha2-containing GABAA receptor modulation is not necessary for benzodiazepine-induced hyperphagia.
Appetite 2009;52(3):675-83.
2009: S A George; P H Hutson; Dai stephens
Differential effects of MPEP and diazepam in tests of conditioned emotional response and Pavlovian-to-instrumental transfer suggests 'anxiolytic' effects are mediated by different mechanisms.
Psychopharmacology 2009;204(3):499-509.
2008: Dai stephens; Theodora Duka
Review. Cognitive and emotional consequences of binge drinking: role of amygdala and prefrontal cortex.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2008;363(1507):3169-79.
2008: Stuart L Rulten; E Hodder; Tamzin L Ripley; Dai stephens; L V Mayne
Alcohol induces DNA damage and the Fanconi anemia D2 protein implicating FANCD2 in the DNA damage response pathways in brain.
Alcoholism, clinical and experimental research 2008;32(7):1186-96.
2008: H V Morris; Gerard R Dawson; David S Reynolds; John R Atack; T W Rosahl; Dai stephens
Alpha2-containing GABA(A) receptors are involved in mediating stimulant effects of cocaine.
Pharmacology, biochemistry, and behavior 2008;90(1):9-18.
2008: C I Dixon; T W Rosahl; Dai stephens
Targeted deletion of the GABRA2 gene encoding alpha2-subunits of GABA(A) receptors facilitates performance of a conditioned emotional response, and abolishes anxiolytic effects of benzodiazepines and barbiturates.
Pharmacology, biochemistry, and behavior 2008;90(1):1-8.
2007: Styliani Vlachou; George Nomikos; Dai stephens; George Panagis
Lack of evidence for appetitive effects of Delta 9-tetrahydrocannabinol in the intracranial self-stimulation and conditioned place preference procedures in rodents.
Behavioural pharmacology 2007;18(4):311-9.
2007: Andy N Mead; Daniel Zamanillo; Nadine Becker; Dai stephens
AMPA-receptor GluR1 subunits are involved in the control over behavior by cocaine-paired cues.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(2):343-53.
2006: Neil Collinson; John R Atack; P Laughton; Gerard R Dawson; Dai stephens
An inverse agonist selective for alpha5 subunit-containing GABAA receptors improves encoding and recall but not consolidation in the Morris water maze.
Psychopharmacology 2006;188(4):619-28.
2006: Stuart L Rulten; Tamzin L Ripley; Ektor Manerakis; Dai stephens; Lynne V Mayne
Ethanol modifies the effect of handling stress on gene expression: problems in the analysis of two-way gene expression studies in mouse brain.
Brain research 2006;1102(1):39-43.
2006: Julie LE MERRER; Dai stephens
Food-induced behavioral sensitization, its cross-sensitization to cocaine and morphine, pharmacological blockade, and effect on food intake.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(27):7163-71.
2006: Gilyana Borlikova; Nicoliene A Elbers; Dai stephens
Repeated withdrawal from ethanol spares contextual fear conditioning and spatial learning but impairs negative patterning and induces over-responding: evidence for effect on frontal cortical but not hippocampal function?
The European journal of neuroscience 2006;24(1):205-16.
2006: H V Morris; Gerard R Dawson; David S Reynolds; John R Atack; Dai stephens
Both alpha2 and alpha3 GABAA receptor subtypes mediate the anxiolytic properties of benzodiazepine site ligands in the conditioned emotional response paradigm.
The European journal of neuroscience 2006;23(9):2495-504.
2006: Andy N Mead; H V Morris; C I Dixon; Stuart L Rulten; Lynne V Mayne; Daniel Zamanillo; Dai stephens
AMPA receptor GluR2, but not GluR1, subunit deletion impairs emotional response conditioning in mice.
Behavioral neuroscience 2006;120(2):241-8.
2006: Stuart L Rulten; Tamzin L Ripley; C L Hunt; Dai stephens; Lynne V Mayne
Sp1 and NFkappaB pathways are regulated in brain in response to acute and chronic ethanol.
Genes, brain, and behavior 2006;5(3):257-73.
2006: Gilyana Borlikova; Julie LE MERRER; Dai stephens
Previous experience of ethanol withdrawal increases withdrawal-induced c-fos expression in limbic areas, but not withdrawal-induced anxiety and prevents withdrawal-induced elevations in plasma corticosterone.
Psychopharmacology 2006;185(2):188-200.
2006: Dai stephens
Animal models/tests of drug addiction: a quest for the holy grail, or the pursuit of wild geese?
Addiction biology 2006;11(1):39-42.
2005: Dai stephens; Jana Pistovcakova; Lynn Worthing; John R Atack; Gerard R Dawson
Role of GABAA alpha5-containing receptors in ethanol reward: the effects of targeted gene deletion, and a selective inverse agonist.
European journal of pharmacology 2005;526(1-3):240-50.
2005: Dai stephens; Tamzin L Ripley; Gilyana Borlikova; Manja Schubert; Doris Albrecht; Lee Hogarth; Theodora Duka
Repeated ethanol exposure and withdrawal impairs human fear conditioning and depresses long-term potentiation in rat amygdala and hippocampus.
Biological psychiatry 2005;58(5):392-400.
2005: Andy N Mead; Geraldine Brown; Julie LE MERRER; Dai stephens
Effects of deletion of gria1 or gria2 genes encoding glutamatergic AMPA-receptor subunits on place preference conditioning in mice.
Psychopharmacology 2005;179(1):164-71.
2005: Hilary J Little; Dai stephens; Tamzin L Ripley; Gilyana Borlikova; Theodora Duka; Manja Schubert; Doris Albrecht; Howard C Becker; Marcelo F Lopez; Friedbert Weiss; Colin Drummond; Michelle Peoples; Christopher L Cunningham
Alcohol withdrawal and conditioning.
Alcoholism, clinical and experimental research 2005;29(3):453-64.
2005: Claire Allison; Judith A Pratt; Tamzin L Ripley; Dai stephens
alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionate receptor autoradiography in mouse brain after single and repeated withdrawal from diazepam.
The European journal of neuroscience 2005;21(4):1045-56.
2004: Dai stephens; Andy N Mead
Behavioural plasticity-induced changes in drug response. Commentary on Badiani and Robinson drug-induced neurobehavioral plasticity: the role of environmental context.
Behavioural pharmacology 2004;15(5-6):377-80.
2004: Jennifer M Horwood; Tamzin L Ripley; Dai stephens
Evidence for disrupted NMDA receptor function in tissue plasminogen activator knockout mice.
Behavioural brain research 2004;150(1-2):127-38.
2004: Theodora Duka; John Gentry; Robert Malcolm; Tamzin L Ripley; Gilyana Borlikova; Dai stephens; Lynn M Veatch; Howard C Becker; Fulton T Crews
Consequences of multiple withdrawals from alcohol.
Alcoholism, clinical and experimental research 2004;28(2):233-46.
2004: Tamzin L Ripley; Gilyana Borlikova; S Lyons; Dai stephens
Selective deficits in appetitive conditioning as a consequence of ethanol withdrawal.
The European journal of neuroscience 2004;19(2):415-25.
2003: Andy N Mead; Dai stephens
Involvement of AMPA receptor GluR2 subunits in stimulus-reward learning: evidence from glutamate receptor gria2 knock-out mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(29):9500-7.
2003: Theodora Duka; Julia M Townshend; Kirsty Collier; Dai stephens
Impairment in cognitive functions after multiple detoxifications in alcoholic inpatients.
Alcoholism, clinical and experimental research 2003;27(10):1563-72.
2003: Anne Jackson; Theodora Duka; Dai stephens
Effects of alcohol and lorazepam during extinction of alcohol self-administration in rats.
Journal of psychopharmacology (Oxford, England) 2003;17(3):293-9.
2003: Tamzin L Ripley; Michael O'Shea; Dai stephens
Repeated withdrawal from ethanol impairs acquisition but not expression of conditioned fear.
The European journal of neuroscience 2003;18(2):441-8.
2003: Tamzin L Ripley; Geraldine Brown; Sarah J Dunworth; Dai stephens
Aversive conditioning following repeated withdrawal from ethanol and epileptic kindling.
The European journal of neuroscience 2003;17(8):1664-70.
2003: Dai stephens; Andy N Mead
What role do GluR1 subunits play in drug abuse?
Trends in neurosciences 2003;26(4):181-2; author reply 182-3.
2003: Anne Jackson; Dai stephens; Theodora Duka
Lorazepam substitutes for the alcohol stimulus in social drinkers.
Psychopharmacology 2003;166(2):181-7.
2003: Andy N Mead; Dai stephens
Selective disruption of stimulus-reward learning in glutamate receptor gria1 knock-out mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(3):1041-8.
2002: Tamzin L Ripley; Christopher A Gadd; Carmen De Felipe; Stephen P Hunt; Dai stephens
Lack of self-administration and behavioural sensitisation to morphine, but not cocaine, in mice lacking NK1 receptors.
Neuropharmacology 2002;43(8):1258-68.
2002: Dai stephens; Andy N Mead; Tamzin L Ripley
Studying the neurobiology of stimulant and alcohol abuse and dependence in genetically manipulated mice.
Behavioural pharmacology 2002;13(5-6):327-45.
2002: Tamzin L Ripley; Sarah J Dunworth; Dai stephens
Consequences of amygdala kindling and repeated withdrawal from ethanol on amphetamine-induced behaviours.
The European journal of neuroscience 2002;16(6):1129-38.
2002: Tamzin L Ripley; Sarah J Dunworth; Dai stephens
Effect of CGP39551 administration on the kindling of ethanol-withdrawal seizures.
Psychopharmacology 2002;163(2):157-65.
2002: Theodora Duka; Julia M Townshend; Kirsty Collier; Dai stephens
Kindling of withdrawal: a study of craving and anxiety after multiple detoxifications in alcoholic inpatients.
Alcoholism, clinical and experimental research 2002;26(6):785-95.
2002: Geraldine Brown; Dai stephens
Effects of cocaine on responding for ethanol or sucrose under a progressive ratio schedule.
Behavioural pharmacology 2002;13(2):157-62.
2002: Sarah J Dunworth; Dai stephens
Provision of cues to signal a withdrawal US prevents the US pre-exposure effect in a diazepam-withdrawal conditioned taste aversion.
Psychopharmacology 2002;160(3):245-52.
2001: Dai stephens; Geraldine Brown; Theodora Duka; Tamzin L Ripley
Impaired fear conditioning but enhanced seizure sensitivity in rats given repeated experience of withdrawal from alcohol.
The European journal of neuroscience 2001;14(12):2023-31.
2001: Jennifer M Horwood; Tamzin L Ripley; Dai stephens
DRL performance in mice with deletion of tPA, uPA or PAI-1 genes.
Behavioural pharmacology 2001;12(6-7):487-96.
2001: Tamzin L Ripley; Jennifer M Horwood; Dai stephens
Evidence for impairment of behavioural inhibition in performance of operant tasks in tPA-/- mice.
Behavioural brain research 2001;125(1-2):215-27.
2001: Anne Jackson; Dai stephens; Theodora Duka
A low dose alcohol drug discrimination in social drinkers: relationship with subjective effects.
Psychopharmacology 2001;157(4):411-20.
2000: J Bergman; Charles France; S G Holtzman; J L Katz; Wouter Koek; Dai stephens
Agonist efficacy, drug dependence, and medications development: preclinical evaluation of opioid, dopaminergic, and GABAA-ergic ligands.
Psychopharmacology 2000;153(1):67-84.
2000: A Jackson; Andy N Mead; Dai stephens
Behavioural effects of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate-receptor antagonists and their relevance to substance abuse.
Pharmacology & therapeutics 2000;88(1):59-76.
2000: Dai stephens; Sarah J Dunworth
Previous experience of diazepam withdrawal prevents the formation of a withdrawal-conditioned taste aversion: test of a blocking hypothesis.
Behavioural pharmacology 2000;11(6):471-81.
2000: Dai stephens; T D Elliman; Sarah J Dunworth
State-dependent behavioural sensitization: evidence from a chlordiazepoxide state.
Behavioural pharmacology 2000;11(2):161-7.
2000: Sarah J Dunworth; Andy N Mead; Dai stephens
Previous experience of withdrawal from chronic diazepam ameliorates the aversiveness of precipitated withdrawal and reduces withdrawal-induced c-fos expression in nucleus accumbens.
The European journal of neuroscience 2000;12(4):1501-8.
1999: J W Smith; WP Watson; Dai stephens; H J Little
The calcium channel antagonist, nimodipine, decreases operant self-administration of low concentrations of ethanol.
Behavioural pharmacology 1999;10(8):793-802.
1999: Dai stephens; Geraldine Brown
Disruption of operant oral self-administration of ethanol, sucrose, and saccharin by the AMPA/kainate antagonist, NBQX, but not the AMPA antagonist, GYKI 52466.
Alcoholism, clinical and experimental research 1999;23(12):1914-20.
1999: Andy N Mead; A Vasilaki; C Spyraki; Theodora Duka; Dai stephens
AMPA-receptor involvement in c-fos expression in the medial prefrontal cortex and amygdala dissociates neural substrates of conditioned activity and conditioned reward.
The European journal of neuroscience 1999;11(11):4089-98.
1999: william wisden; Dai stephens
Towards better benzodiazepines.
Nature 1999;401(6755):751-2.
1999: Theodora Duka; Anne Jackson; D C Smith; Dai stephens
Relationship of components of an alcohol interoceptive stimulus to induction of desire for alcohol in social drinkers.
Pharmacology, biochemistry, and behavior 1999;64(2):301-9.
1999: Andy N Mead; Dai stephens
CNQX but not NBQX prevents expression of amphetamine-induced place preference conditioning: a role for the glycine site of the NMDA receptor, but not AMPA receptors.
The Journal of pharmacology and experimental therapeutics 1999;290(1):9-15.
1999: Tamzin L Ripley; Beatriz A Rocha; Michael W Oglesby; Dai stephens
Increased sensitivity to cocaine, and over-responding during cocaine self-administration in tPA knockout mice.
Brain research 1999;826(1):117-27.
1998: Theodora Duka; R Tasker; Dai stephens
Alcohol choice and outcome expectancies in social drinkers.
Behavioural pharmacology 1998;9(7):643-53.
1998: Andy N Mead; Dai stephens
AMPA-receptors are involved in the expression of amphetamine-induced behavioural sensitisation, but not in the expression of amphetamine-induced conditioned activity in mice.
Neuropharmacology 1998;37(9):1131-8.
1998: Anne Jackson; Andy N Mead; Beatriz A Rocha; Dai stephens
AMPA receptors and motivation for drug: effect of the selective antagonist NBQX on behavioural sensitization and on self-administration in mice.
Behavioural pharmacology 1998;9(5-6):457-67.
1998: Theodora Duka; R Tasker; K Russell; Dai stephens
Discriminative stimulus properties of nicotine at low doses: the effects of caffeine preload.
Behavioural pharmacology 1998;9(3):219-29.
1998: Theodora Duka; Dai stephens; C Russell; R Tasker
Discriminative stimulus properties of low doses of ethanol in humans.
Psychopharmacology 1998;136(4):379-89.
1998: Sarah J Dunworth; Dai stephens
Sensitisation to repeated withdrawal, in mice treated chronically with diazepam, is blocked by an NMDA receptor antagonist.
Psychopharmacology 1998;136(3):308-10.
1998: Geraldine Brown; Anne Jackson; Dai stephens
Effects of repeated withdrawal from chronic ethanol on oral self-administration of ethanol on a progressive ratio schedule.
Behavioural pharmacology 1998;9(2):149-61.
1998: B O Ward; Dai stephens
Sensitisation of withdrawal signs following repeated withdrawal from a benzodiazepine: differences between measures of anxiety and seizure sensitivity.
Psychopharmacology 1998;135(4):342-52.
1997: Graziano Pinna; R Galici; H H Schneider; Dai stephens; Lechoslaw Turski
Alprazolam dependence prevented by substituting with the beta-carboline abecarnil.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2719-23.
1996: Anne Jackson; Geraldine Brown; Dai stephens
N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4- isoxazoleproprionate (AMPA) glutamate-receptor antagonists have different interactions with the discriminative stimuli of abused drugs.
Psychopharmacology 1996;128(3):320-7.
1996: Dai stephens; B J Cole
AMPA antagonists differ from NMDA antagonists in their effects on operant DRL and delayed matching to position tasks.
Psychopharmacology 1996;126(3):249-59.
1996: André Rex; Dai stephens; Heidrun Fink
"Anxiolytic" action of diazepam and abecarnil in a modified open field test.
Pharmacology, biochemistry, and behavior 1996;53(4):1005-11.
1995: D A Lytle; M W Emmett-Oglesby; Dai stephens
Discriminative stimulus effects of midazolam and abecarnil in rats treated chronically with diazepam or abecarnil.
Psychopharmacology 1995;121(3):339-46.
1995: H H Schneider; M Yamaguchi; J S Andrews; Dai stephens
Discriminative stimulus properties of the stereoisomers of the phosphodiesterase inhibitor rolipram.
Pharmacology, biochemistry, and behavior 1995;50(2):211-7.
1995: Vladimir S Vorobjev; Irina N Sharonova; V G Skrebitsky; H H Schneider; Dai stephens
Abecarnil enhances GABA-induced currents in acutely isolated cerebellar Purkinje cells.
Neuropharmacology 1995;34(2):157-63.
1994: G H Jones; C Schneider; H H Schneider; J Seidler; B J Cole; Dai stephens
Comparison of several benzodiazepine receptor ligands in two models of anxiolytic activity in the mouse: an analysis based on fractional receptor occupancies.
Psychopharmacology 1994;114(2):191-9.
1994: J S Andrews; M Grützner; Dai stephens
The effects of ibotenic acid lesions of the basal forebrain on visual discrimination performance in rats.
Brain research bulletin 1994;34(4):407-12.
1993: L Turski; Dai stephens
Effect of the beta-carboline abecarnil on spinal reflexes in mice and on muscle tone in genetically spastic rats: a comparison with diazepam.
The Journal of pharmacology and experimental therapeutics 1993;267(3):1215-20.
1993: Dai stephens; L Turski
Kindling to the benzodiazepine receptor inverse agonist, FG 7142: evidence for involvement of NMDA, but not non-NMDA, glutamatergic receptors.
Neuropharmacology 1993;32(10):1011-7.
1993: K G Steppuhn; H H Schneider; L Turski; Dai stephens
Long-term treatment with abecarnil does not induce diazepam-like dependence in mice.
The Journal of pharmacology and experimental therapeutics 1993;264(3):1395-400.
1993: Dai stephens; L Turski; G H Jones; K G Steppuhn; H H Schneider
Abecarnil: a novel anxiolytic with mixed full agonist/partial agonist properties in animal models of anxiety and sedation.
Psychopharmacology series 1993;11():79-95.
1993: I Pribilla; R Neuhaus; R Huba; M Hillmann; J D Turner; Dai stephens; H H Schneider
Abecarnil is a full agonist at some, and a partial agonist at other recombinant GABAA receptor subtypes.
Psychopharmacology series 1993;11():50-61.
1993: B J Cole; M Klewer; G H Jones; Dai stephens
Contrasting effects of the competitive NMDA antagonist CPP and the non-competitive NMDA antagonist MK 801 on performance of an operant delayed matching to position task in rats.
Psychopharmacology 1993;111(4):465-71.
1992: H Clusmann; J Stabel; Dai stephens; Uwe Heinemann
Alterations in medial perforant path and mossy fiber induced field potentials in amygdala and beta-carboline (FG 7142) kindled rats.
Neuroscience letters 1992;146(1):65-8.
1992: Anton M L Coenen; Dai stephens; Gilles van Luijtelaar
Effects of the beta-carboline abecarnil on epileptic activity, EEG, sleep and behavior of rats.
Pharmacology, biochemistry, and behavior 1992;42(3):401-5.
1992: L Turski; Dai stephens
Excitatory amino acid antagonists protect mice against MPP+ seizures.
Synapse (New York, N.Y.) 1992;10(2):120-5.
1992: L Turski; P Jacobsen; T Honoré; Dai stephens
Relief of experimental spasticity and anxiolytic/anticonvulsant actions of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline.
The Journal of pharmacology and experimental therapeutics 1992;260(2):742-7.
1992: J S Andrews; M Grützner; Dai stephens
Effects of cholinergic and non-cholinergic drugs on visual discrimination and delayed visual discrimination performance in rats.
Psychopharmacology 1992;106(4):523-30.
1992: Dai stephens; L Turski; M Hillman; J D Turner; H H Schneider; M Yamaguchi
What are the differences between abecarnil and conventional benzodiazepine anxiolytics?
Advances in biochemical psychopharmacology 1992;47():395-405.
1990: L Turski; K Bressler; T Klockgether; Dai stephens
Differential effects of the excitatory amino acid antagonists, 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 3-((+-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP), on spinal reflex activity in mice.
Neuroscience letters 1990;113(1):66-71.
1990: L Turski; Dai stephens; LH Jensen; E N Petersen; B S Meldrum; S Patel; J B Hansen; W Löscher; H H Schneider; R Schmiechen
Anticonvulsant action of the beta-carboline abecarnil: studies in rodents and baboon, Papio papio.
The Journal of pharmacology and experimental therapeutics 1990;253(1):344-52.
1990: Dai stephens; H H Schneider; W Kehr; J S Andrews; K J Rettig; L Turski; R Schmiechen; J D Turner; LH Jensen; E N Petersen
Abecarnil, a metabolically stable, anxioselective beta-carboline acting at benzodiazepine receptors.
The Journal of pharmacology and experimental therapeutics 1990;253(1):334-43.
1990: L Turski; W Niemann; Dai stephens
Differential effects of antiepileptic drugs and beta-carbolines on seizures induced by excitatory amino acids.
Neuroscience 1990;39(3):799-807.
1990: J S Andrews; Dai stephens
Drug discrimination models in anxiety and depression.
Pharmacology & therapeutics 1990;47(2):267-80.
1989: Dai stephens; L A Turski; J D Turner; H H Schneider
Are changes in glutamatergic mechanisms responsible for kindling to the benzodiazepine receptor inverse agonist, FG 7142?
British journal of pharmacology 1989;98 Suppl():837P.
1989: L N Zimmermann; H H Schneider; Dai stephens
Partial GABA agonist activity of SR 95531 on the binding of [35S]TBPS, [3H]DMCM and [3H]lormetazepam to rat brain membranes.
Biochemical pharmacology 1989;38(17):2889-93.
1989: Dai stephens; R Weidmann
Blockade of FG 7142 kindling by anticonvulsants acting at sites distant from the benzodiazepine receptor.
Brain research 1989;492(1-2):89-98.
1989: L N Zimmermann; H H Schneider; Dai stephens
Binding characteristics reveal partial GABA agonist activities of SR 95531.
Journal of protein chemistry 1989;8(3):355-6.
1989: M Sarter; Dai stephens
Disinhibitory properties of beta-carboline antagonists of benzodiazepine receptors: a possible therapeutic approach for senile dementia?
Biochemical Society transactions 1989;17(1):81-3.
1988: Dai stephens; M Sarter; Theodora Duka; R Dorow; H H Schneider
[New approaches in memory research. The beta-carboline substance class].
Fortschritte der Medizin 1988;106(33):675-6, 677.
1988: H H Schneider; Dai stephens
Co-existence of kindling induced by the beta-carboline, FG 7142, and tolerance to diazepam following chronic treatment in mice.
European journal of pharmacology 1988;154(1):35-45.
1988: Wolfgang Löscher; Dai stephens
Chronic treatment with diazepam or the inverse benzodiazepine receptor agonist FG 7142 causes differential changes in the effects of GABA receptor stimulation.
Epilepsy research 1988;2(4):253-9.
1988: M Sarter; Dai stephens
Beta-carbolines as tools in memory research: animal data and speculations.
Psychopharmacology series 1988;6():230-45.
1988: Dai stephens; M Sarter
Bidirectional nature of benzodiazepine receptor ligands extends to effects on vigilance.
Psychopharmacology series 1988;6():205-17.
1988: Martin Sarter; G Bodewitz; Dai stephens
Attenuation of scopolamine-induced impairment of spontaneous alteration behaviour by antagonist but not inverse agonist and agonist beta-carbolines.
Psychopharmacology 1988;94(4):491-5.
1988: M Sarter; H H Schneider; Dai stephens
Treatment strategies for senile dementia: antagonist beta-carbolines.
Trends in neurosciences 1988;11(1):13-7.
1988: Dai stephens; H H Schneider; R Weidmann; L Zimmermann
Decreased sensitivity to benzodiazepine receptor agonists and increased sensitivity to inverse agonists following chronic treatments: evidence for separate mechanisms.
Advances in biochemical psychopharmacology 1988;45():337-54.
1987: LH Jensen; Dai stephens; M Sarter; E N Petersen
Bidirectional effects of beta-carbolines and benzodiazepines on cognitive processes.
Brain research bulletin 1987;19(3):359-64.
1987: Dai stephens; H H Schneider; W Kehr; LH Jensen; E Petersen; T Honore
Modulation of anxiety by beta-carbolines and other benzodiazepine receptor ligands: relationship of pharmacological to biochemical measures of efficacy.
Brain research bulletin 1987;19(3):309-18.
1987: Theodora Duka; Dai stephens; Werner Krause; R Dorow
Human studies on the benzodiazepine receptor antagonist beta-carboline ZK 93,426: preliminary observations on psychotropic activity.
Psychopharmacology 1987;93(4):421-7.
1986: T Duka; Dai stephens
Potentiation of the propunishment, but not the convulsant action of the beta-carboline DMCM by naltrexone.
Pharmacology, biochemistry, and behavior 1986;25(3):595-8.
1986: LJ Herberg; A M J Montgomery; S E File; S Pellow; Dai stephens
Effect on hypothalamic self-stimulation of the novel beta-carbolines ZK 93 426 (a benzodiazepine receptor antagonist) and ZK 91 296 (a putative partial agonist).
Journal of neural transmission 1986;66(2):75-84.
1986: Dai stephens; B S Meldrum; R Weidmann; C Schneider; M Grützner
Does the excitatory amino acid receptor antagonist 2-APH exhibit anxiolytic activity?
Psychopharmacology 1986;90(2):166-9.
1986: Dai stephens; W Kehr; T Duka
Anxiolytic and anxiogenic beta-carbolines: tools for the study of anxiety mechanisms.
Advances in biochemical psychopharmacology 1986;41():91-106.
1985: Dai stephens; R Weidmann; D Quartermain; M Sarter
Reversal learning in senescent rats.
Behavioural brain research 1985;17(3):193-202.
1985: Dai stephens; H H Schneider
Tolerance to the benzodiazepine diazepam in an animal model of anxiolytic activity.
Psychopharmacology 1985;87(3):322-7.
1985: Dai stephens; W Kehr
Beta-carbolines can enhance or antagonize the effects of punishment in mice.
Psychopharmacology 1985;85(2):143-7.
1985: Dai stephens; W Kehr; H Wachtel; R Schmiechen
The anxiolytic activity of beta-carboline derivatives in mice, and its separation from ataxic properties.
Pharmacopsychiatry 1985;18(1):167-70.
1984: J L Smart; Dai stephens; J Tonkiss; N S Auestad; J Edmond
Growth and development of rats artificially reared on different milk-substitutes.
The British journal of nutrition 1984;52(2):227-37.
1984: Dai stephens; W Kehr; H H Schneider; R Schmiechen
Beta-carbolines with agonistic and inverse agonistic properties at benzodiazepine receptors of the rat.
Neuroscience letters 1984;47(3):333-8.
1984: LH Jensen; E N Petersen; C Braestrup; T Honoré; W Kehr; Dai stephens; H Schneider; D Seidelmann; R Schmiechen
Evaluation of the beta-carboline ZK 93 426 as a benzodiazepine receptor antagonist.
Psychopharmacology 1984;83(3):249-56.
1984: E N Petersen; LH Jensen; T Honoré; C Braestrup; W Kehr; Dai stephens; H Wachtel; D Seidelman; R Schmiechen
ZK 91296, a partial agonist at benzodiazepine receptors.
Psychopharmacology 1984;83(3):240-8.
1984: Dai stephens; G T Shearman; W Kehr
Discriminative stimulus properties of beta-carbolines characterized as agonists and inverse agonists at central benzodiazepine receptors.
Psychopharmacology 1984;83(3):233-9.
1983: J L Smart; Dai stephens; H B Katz
Growth and development of rats artificially reared on a high or a low plane of nutrition.
The British journal of nutrition 1983;49(3):497-506.
1982: Dai stephens
Hoarding behaviour and the defence of body weight in adult rats, following undernutrition during different periods of early development.
The Quarterly journal of experimental psychology. B, Comparative and physiological psychology 1982;34 (Pt 4)():183-94.
1982: A Latham; D H Paul; J L Smart; Dai stephens
Comparison of cerebellar Purkinje cell simple spike discharges in adult rats after undernutrition during the suckling period and nutritionally normal rats.
Brain research 1982;256(2):223-7.
1982: N J Rothwell; Dai stephens; M J Stock
Changes in metabolic rate and brown adipose tissue composition during nutritional rehabilitation of postnatally undernourished rats.
Biology of the neonate 1982;42(1-2):93-9.
1982: Dai stephens; J Tonkiss; J H Wearden
Differences between rats and undernourished preweaning, and controls in learning about a redundant stimulus during acquisition of a conditioned emotional response.
Physiology & behavior 1982;28(1):95-101.
1981: Dai stephens; S C Nash; C Proffitt
Dietary obesity in adult and weanling rats following removal of interscapular brown adipose tissue.
Pflügers Archiv : European journal of physiology 1981;392(1):7-12.
1981: Dai stephens; J Tonkiss
Rats undernourished as infants differ from controls in learning about a compound but not a simple discriminative stimulus.
Physiology & behavior 1981;26(5):803-8.
1980: Dai stephens
Growth and the development of dietary obesity in adulthood of rats which have been undernourished during development.
The British journal of nutrition 1980;44(3):215-27.
1980: Dai stephens
Does the Lee obesity index measure general obesity?
Physiology & behavior 1980;25(2):313-5.
1980: Dai stephens
Dietarily obese rats become leaner than controls when palatable food is withdrawn.
The Proceedings of the Nutrition Society 1980;39(2):39A.
1979: Dai stephens; L J Herberg
Dopamine--acetylcholine "balance" in nucleus accumbens and corpus striatum and its effect on hypothalamic self-stimulation.
European journal of pharmacology 1979;54(4):331-9.
1977: Dai stephens; L J Herberg
Effects on hypothalamic self-stimulation of drugs influencing dopaminergic neurotransmission injected into nucleus accumbens and corpus striatum of rats.
Psychopharmacology 1977;54(1):81-5.
1977: L J Herberg; Dai stephens
Interaction of hunger and thirst in the motivational arousal underlying hoarding behavior in the rat.
Journal of comparative and physiological psychology 1977;91(2):359-64.
1977: S M Morrissey; Dai stephens; D E Webber
The role of the posterior hypothalamus in hypoglycaemia and gastric secretion [proceedings].
The Journal of physiology 1977;266(1):85P-86P.
1976: L J Herberg; Dai stephens; Keith B J Franklin
Catecholamines and self-stimulation: evidence suggesting a reinforcing role for noradrenaline and a motivating role for dopamine.
Pharmacology, biochemistry, and behavior 1976;4(5):575-82.
1976: L J Herberg; Dai stephens
Cyclic AMP and central noradrenaline receptors: failure to activate diencephalic adrenergic feeding pathways.
Pharmacology, biochemistry, and behavior 1976;4(1):107-10.
1975: Dai stephens; L J Herberg
Catecholamines and self-stimulation: pharmacological differences between near- and far-lateral hypothalamic sites.
Brain research 1975;90(2):348-51.
1975: Dai stephens; S M Morrissey
Hypothalamic stimulation induces acid secretion, hypoglycemia, and hyperinsulinemia.
The American journal of physiology 1975;228(4):1206-9.
1975: L J Herberg; Dai stephens
Catecholamines and self-stimulation: the action of amantadine and its interaction with amphetamine.
Pharmacology, biochemistry, and behavior 1975;3(2):263-9.
1975: Dai stephens; L J Herberg
Letter: obesity and glucose receptors.
Lancet 1975;1(7905):521.
1972: S Morrissey; Dai stephens
The role of the posterior hypothalamus in gastric acid secretion.
The Journal of physiology 1972;221(1):14P-15P.