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Erwin Sigel

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Erwin Sigel; Michael E Steinmann
Structure, function, and modulation of GABA(A) receptors.
Lucia Kuhn-Nentwig; Benjamin P Lüscher; Irina M Fedorova; Lukas S Kopp; Wolfgang Nentwig; Johann Schaller; Thomas Seebeck; Erwin Sigel; Kathrin Streitberger; Christian Trachsel; Xuan Lan Vu; Lev G Magazanik
A venom-derived neurotoxin, CsTx-1, from the spider Cupiennius salei exhibits cytolytic activities.
Amaia Gonzalez-Salgado; Eva Greganova; Pascal Mäser; Monika Rauch; Erwin Sigel; Michael E Steinmann; Peter Bütikofer
myo-Inositol uptake is essential for bulk inositol phospholipid but not glycosylphosphatidylinositol synthesis in Trypanosoma brucei.

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All Publications

2012: Erwin Sigel; Michael E Steinmann
Structure, function, and modulation of GABA(A) receptors.
The Journal of biological chemistry 2012;287(48):40224-31.
2012: Lucia Kuhn-Nentwig; Benjamin P Lüscher; Irina M Fedorova; Lukas S Kopp; Wolfgang Nentwig; Johann Schaller; Thomas Seebeck; Erwin Sigel; Kathrin Streitberger; Christian Trachsel; Xuan Lan Vu; Lev G Magazanik
A venom-derived neurotoxin, CsTx-1, from the spider Cupiennius salei exhibits cytolytic activities.
The Journal of biological chemistry 2012;287(30):25640-9.
2012: Amaia Gonzalez-Salgado; Eva Greganova; Pascal Mäser; Monika Rauch; Erwin Sigel; Michael E Steinmann; Peter Bütikofer
myo-Inositol uptake is essential for bulk inositol phospholipid but not glycosylphosphatidylinositol synthesis in Trypanosoma brucei.
The Journal of biological chemistry 2012;287(16):13313-23.
2012: Roland Baur; Jürg Gertsch; Erwin Sigel
The cannabinoid CB1 receptor antagonists rimonabant (SR141716) and AM251 directly potentiate GABA(A) receptors.
British journal of pharmacology 2012;165(8):2479-84.
2012: Benjamin P Lüscher; Roland Baur; Maurice Goeldner; Erwin Sigel
Influence of GABA(A) receptor α subunit isoforms on the benzodiazepine binding site.
PloS one 2012;7(7):e42101.
2011: Erwin Sigel; Trevor G Smart; Andreas Zimmer; Roland Baur; Janine Marazzi; Ildiko Rácz; Jürg Gertsch
The major central endocannabinoid directly acts at GABA(A) receptors.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(44):18150-5.
2011: Erwin Sigel; Benjamin P Lüscher
A closer look at the high affinity benzodiazepine binding site on GABAA receptors.
Current topics in medicinal chemistry 2011;11(2):241-6.
2010: Roland Baur; Benjamin P Lüscher; Lars Richter; Erwin Sigel
A residue close to α1 loop F disrupts modulation of GABAA receptors by benzodiazepines while their binding is maintained.
Journal of neurochemistry 2010;115(6):1478-85.
2010: Lucien Rufener; Roland Baur; Ronald Kaminsky; Pascal Mäser; Erwin Sigel
Monepantel allosterically activates DEG-3/DES-2 channels of the gastrointestinal nematode Haemonchus contortus.
Molecular pharmacology 2010;78(5):895-902.
2010: Roland Baur; Kuldeep H Kaur; Erwin Sigel
Diversity of structure and function of alpha1alpha6beta3delta GABAA receptors: comparison with alpha1beta3delta and alpha6beta3delta receptors.
The Journal of biological chemistry 2010;285(23):17398-405.
2009: Erwin Sigel; Kuldeep H Kaur; Benjamin P Lüscher; Roland Baur
Use of concatamers to study GABAA receptor architecture and function: application to delta-subunit-containing receptors and possible pitfalls.
Biochemical Society transactions 2009;37(Pt 6):1338-42.
2009: Kelly R Tan; Roland Baur; Sébastien Charon; Maurice Goeldner; Erwin Sigel
Relative positioning of diazepam in the benzodiazepine-binding-pocket of GABA receptors.
Journal of neurochemistry 2009;111(5):1264-73.
2009: Roland Baur; Kuldeep H Kaur; Erwin Sigel
Structure of alpha6 beta3 delta GABA(A) receptors and their lack of ethanol sensitivity.
Journal of neurochemistry 2009;111(5):1172-81.
2009: Kuldeep H Kaur; Roland Baur; Erwin Sigel
Unanticipated structural and functional properties of delta-subunit-containing GABAA receptors.
The Journal of biological chemistry 2009;284(12):7889-96.
2008: Roland Baur; Kelly R Tan; Benjamin P Lüscher; Anne Gonthier; Maurice Goeldner; Erwin Sigel
Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs.
Journal of neurochemistry 2008;106(6):2353-63.
2008: Jean-Marc Burgunder; Shang Huifang; Pascal Beguin; Roland Baur; Chew Soh Eng; Raymond C S Seet; Erle C H Lim; Benjamin K C Ong; Walter Hunziker; Erwin Sigel
Novel chloride channel mutations leading to mild myotonia among Chinese.
Neuromuscular disorders : NMD 2008;18(8):633-40.
2008: Verena Niggli; Erwin Sigel
Anticipating antiport in P-type ATPases.
Trends in biochemical sciences 2008;33(4):156-60.
2008: Karen A Bollan; Roland Baur; Tim G Hales; Erwin Sigel; Christopher N Connolly
The promiscuous role of the epsilon subunit in GABAA receptor biogenesis.
Molecular and cellular neurosciences 2008;37(3):610-21.
2007: Roland Baur; Erwin Sigel
Replacement of histidine in position 105 in the α₅ subunit by cysteine stimulates zolpidem sensitivity of α₅β₂γ₂ GABA(A) receptors.
Journal of neurochemistry 2007;103(6):2556-64.
2007: Kelly R Tan; Roland Baur; Anne Gonthier; Maurice Goeldner; Erwin Sigel
Two neighboring residues of loop A of the alpha1 subunit point towards the benzodiazepine binding site of GABAA receptors.
FEBS letters 2007;581(24):4718-22.
2007: Kelly R Tan; Anne Gonthier; Roland Baur; Margot Ernst; Maurice Goeldner; Erwin Sigel
Proximity-accelerated chemical coupling reaction in the benzodiazepine-binding site of gamma-aminobutyric acid type A receptors: superposition of different allosteric modulators.
The Journal of biological chemistry 2007;282(36):26316-25.
2006: Erwin Sigel; Roland Baur; N Boulineau; Frédéric Minier
Impact of subunit positioning on GABAA receptor function.
Biochemical Society transactions 2006;34(Pt 5):868-71.
2006: Roland Baur; Frédéric Minier; Erwin Sigel
A GABA(A) receptor of defined subunit composition and positioning: concatenation of five subunits.
FEBS letters 2006;580(6):1616-20.
2005: Nathalie Boulineau; Roland Baur; Frédéric Minier; Erwin Sigel
Consequence of the presence of two different beta subunit isoforms in a GABA(A) receptor.
Journal of neurochemistry 2005;95(6):1724-31.
2005: Roland Baur; Erwin Sigel
Influence of the point mutation alpha-1-H101R on the assembly of gamma-aminobutyric acid type A receptors.
Neuroreport 2005;16(17):1955-8.
2005: Roland Baur; Urs Simmen; Martin Senn; Urs Séquin; Erwin Sigel
Novel plant substances acting as beta subunit isoform-selective positive allosteric modulators of GABAA receptors.
Molecular pharmacology 2005;68(3):787-92.
2005: Roland Baur; Erwin Sigel
Benzodiazepines affect channel opening of GABA A receptors induced by either agonist binding site.
Molecular pharmacology 2005;67(4):1005-8.
2005: Erwin Sigel; Frédéric Minier
The Xenopus oocyte: system for the study of functional expression and modulation of proteins.
Molecular nutrition & food research 2005;49(3):228-34.
2005: Dmytro Berezhnoy; Roland Baur; Anne Gonthier; Bernard Foucaud; Maurice Goeldner; Erwin Sigel
Conformational changes at benzodiazepine binding sites of GABA(A) receptors detected with a novel technique.
Journal of neurochemistry 2005;92(4):859-66.
2004: Frédéric Minier; Erwin Sigel
Techniques: Use of concatenated subunits for the study of ligand-gated ion channels.
Trends in pharmacological sciences 2004;25(9):499-503.
2004: Dominique Kavvadias; Philipp Sand; Kuresh A Youdim; M Zeeshan Qaiser; Catherine Rice-Evans; Roland Baur; Erwin Sigel; Wolf-Dieter Rausch; Peter Riederer; Peter Schreier
The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses the blood-brain barrier and exhibits anticonvulsive effects.
British journal of pharmacology 2004;142(5):811-20.
2004: David Cope; Peer Wulff; Alessandra Oberto; M I Aller; Marco Capogna; Francesco Ferraguti; C Halbsguth; H Hoeger; Helen E Jolin; Alison Jones; Andrew N J McKenzie; Waltraud Ogris; A Poeltl; Saku T Sinkkonen; Olga Vekovischeva; Esa R Korpi; Werner Sieghart; Erwin Sigel; Peter Somogyi; william wisden
Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor gamma2 subunit.
Neuropharmacology 2004;47(1):17-34.
2004: Frédéric Minier; Erwin Sigel
Positioning of the alpha-subunit isoforms confers a functional signature to gamma-aminobutyric acid type A receptors.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(20):7769-74.
2004: Lie Chen; Martin Schaerer; Zen H Lu; Doris Lang; Franziska Joncourt; Joachim Weis; Jürg Fritschi; Liliane Kappeler; Sabina Gallati; Erwin Sigel; Jean-Marc Burgunder
Exon 17 skipping in CLCN1 leads to recessive myotonia congenita.
Muscle & nerve 2004;29(5):670-6.
2004: Dmytro Berezhnoy; Yves Nyfeler; Anne Gonthier; Hervé Schwob; Maurice Goeldner; Erwin Sigel
On the benzodiazepine binding pocket in GABAA receptors.
The Journal of biological chemistry 2004;279(5):3160-8.
2003: Michael S Y Huen; Kwok-Min Hui; Justin W C Leung; Erwin Sigel; Roland Baur; Joseph T Y Wong; Hong Xue
Naturally occurring 2'-hydroxyl-substituted flavonoids as high-affinity benzodiazepine site ligands.
Biochemical pharmacology 2003;66(12):2397-407.
2003: Sabine W Baumann; Roland Baur; Erwin Sigel
Individual properties of the two functional agonist sites in GABA(A) receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(35):11158-66.
2003: Roland Baur; Erwin Sigel
On high- and low-affinity agonist sites in GABAA receptors.
Journal of neurochemistry 2003;87(2):325-32.
2002: Sabine W Baumann; Roland Baur; Erwin Sigel
Forced subunit assembly in alpha1beta2gamma2 GABAA receptors. Insight into the absolute arrangement.
The Journal of biological chemistry 2002;277(48):46020-5.
2002: Kwok-Min Hui; Michael S Y Huen; Hong Yan Wang; Hui Zheng; Erwin Sigel; Roland Baur; Hong Ren; Zhi-Wang Li; Joseph T Y Wong; Hong Xue
Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi.
Biochemical pharmacology 2002;64(9):1415-24.
2002: Andrew J Boileau; Roland Baur; L M Sharkey; Erwin Sigel; Cynthia Czajkowski
The relative amount of cRNA coding for gamma2 subunits affects stimulation by benzodiazepines in GABA(A) receptors expressed in Xenopus oocytes.
Neuropharmacology 2002;43(4):695-700.
2002: Andreas Buhr; Matt T Bianchi; Roland Baur; Philippe Courtet; Virginie Pignay; Jean-Philippe Boulenger; Sabina Gallati; David J Hinkle; Robert L Macdonald; Erwin Sigel
Functional characterization of the new human GABA(A) receptor mutation beta3(R192H).
Human genetics 2002;111(2):154-60.
2002: Erwin Sigel
Mapping of the benzodiazepine recognition site on GABA(A) receptors.
Current topics in medicinal chemistry 2002;2(8):833-9.
2002: Ahmed El Hadri; Ahmed Abouabdellah; Urs Thomet; Roland Baur; Roman Furtmüller; Erwin Sigel; Werner Sieghart; Robert H Dodd
N-Substituted 4-amino-3,3-dipropyl-2(3H)-furanones: new positive allosteric modulators of the GABA(A) receptor sharing electrophysiological properties with the anticonvulsant loreclezole.
Journal of medicinal chemistry 2002;45(13):2824-31.
2001: Sabine W Baumann; Roland Baur; Erwin Sigel
Subunit arrangement of gamma-aminobutyric acid type A receptors.
The Journal of biological chemistry 2001;276(39):36275-80.
2001: Martin Schaerer; K Kannenberg; Peter Hunziker; Sabine W Baumann; Erwin Sigel
Interaction between GABA(A) receptor beta subunits and the multifunctional protein gC1q-R.
The Journal of biological chemistry 2001;276(28):26597-604.
2001: Erwin Sigel; Roland Baur; Roman Furtmueller; R Razet; Robert H Dodd; Werner Sieghart
Differential cross talk of ROD compounds with the benzodiazepine binding site.
Molecular pharmacology 2001;59(6):1470-7.
2001: Andreas Buhr; C Wagner; Karoline Fuchs; Werner Sieghart; Erwin Sigel
Two novel residues in M2 of the gamma-aminobutyric acid type A receptor affecting gating by GABA and picrotoxin affinity.
The Journal of biological chemistry 2001;276(11):7775-81.
2000: R Razet; Urs Thomet; Roman Furtmüller; F Jursky; Erwin Sigel; Werner Sieghart; Robert H Dodd
Use of bicuculline, a GABA antagonist, as a template for the development of a new class of ligands showing positive allosteric modulation of the GABA(A) receptor.
Bioorganic & medicinal chemistry letters 2000;10(22):2579-83.
2000: Urs Thomet; Roland Baur; Robert H Dodd; Erwin Sigel
Loreclezole as a simple functional marker for homomeric rho type GABA(C) receptors.
European journal of pharmacology 2000;408(2):R1-2.
2000: R Razet; Urs Thomet; Roman Furtmüller; Angèle Chiaroni; Erwin Sigel; Werner Sieghart; Robert H Dodd
5-[1'-(2'-N-Arylsulfonyl-1',2',3',4'-tetrahydroisoquinolyl)]-4, 5-dihydro-2(3H)-furanones: positive allosteric modulators of the GABA(A) receptor with a new mode of action.
Journal of medicinal chemistry 2000;43(23):4363-6.
2000: Urs Thomet; Roland Baur; R Razet; Robert H Dodd; Roman Furtmüller; Werner Sieghart; Erwin Sigel
A novel positive allosteric modulator of the GABA(A) receptor: the action of (+)-ROD188.
British journal of pharmacology 2000;131(4):843-50.
2000: Erwin Sigel; Roland Baur
Electrophysiological evidence for the coexistence of alpha1 and alpha6 subunits in a single functional GABA(A) receptor.
Journal of neurochemistry 2000;74(6):2590-6.
2000: F Jursky; Karoline Fuchs; Andreas Buhr; Verena Tretter; Erwin Sigel; Werner Sieghart
Identification of amino acid residues of GABA(A) receptor subunits contributing to the formation and affinity of the tert-butylbicyclophosphorothionate binding site.
Journal of neurochemistry 2000;74(3):1310-6.
1999: Erwin Sigel; Andreas Buhr; Roland Baur
Role of the conserved lysine residue in the middle of the predicted extracellular loop between M2 and M3 in the GABA(A) receptor.
Journal of neurochemistry 1999;73(4):1758-64.
1999: K Kannenberg; Martin Schaerer; Karoline Fuchs; Werner Sieghart; Erwin Sigel
A novel serine kinase with specificity for beta3-subunits is tightly associated with GABA(A) receptors.
The Journal of biological chemistry 1999;274(30):21257-64.
1999: Urs Thomet; Roman Furtmüller; Werner Sieghart; M Le Hyaric-Almeida; J F Rousseau; Robert H Dodd; Patrice Venault; Georges Chapouthier; Erwin Sigel
EDPC: a novel high affinity ligand for the benzodiazepine site on rat GABA(A) receptors.
Neuroscience letters 1999;269(2):63-6.
1999: Urs Thomet; Roland Baur; P Scholze; Werner Sieghart; Erwin Sigel
Dual mode of stimulation by the beta-carboline ZK 91085 of recombinant GABA(A) receptor currents: molecular determinants affecting its action.
British journal of pharmacology 1999;127(5):1231-9.
1998: Erwin Sigel; Martin Schaerer; Andreas Buhr; Roland Baur
The benzodiazepine binding pocket of recombinant alpha1beta2gamma2 gamma-aminobutyric acidA receptors: relative orientation of ligands and amino acid side chains.
Molecular pharmacology 1998;54(6):1097-105.
1998: Martin Schaerer; Andreas Buhr; Roland Baur; Erwin Sigel
Amino acid residue 200 on the alpha1 subunit of GABA(A) receptors affects the interaction with selected benzodiazepine binding site ligands.
European journal of pharmacology 1998;354(2-3):283-7.
1998: Erwin Sigel; Roland Baur; R Netzer; Chris Rundfeldt
The antiepileptic drug AWD 131-138 stimulates different recombinant isoforms of the rat GABA(A) receptor through the benzodiazepine binding site.
Neuroscience letters 1998;245(2):85-8.
1997: Erwin Sigel; Andreas Buhr
The benzodiazepine binding site of GABAA receptors.
Trends in pharmacological sciences 1997;18(11):425-9.
1997: Andreas Buhr; Martin Schaerer; Roland Baur; Erwin Sigel
Residues at positions 206 and 209 of the alpha1 subunit of gamma-aminobutyric AcidA receptors influence affinities for benzodiazepine binding site ligands.
Molecular pharmacology 1997;52(4):676-82.
1997: Andreas Buhr; Erwin Sigel
A point mutation in the gamma2 subunit of gamma-aminobutyric acid type A receptors results in altered benzodiazepine binding site specificity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(16):8824-9.
1997: Andreas Buhr; Roland Baur; Erwin Sigel
Subtle changes in residue 77 of the gamma subunit of alpha1beta2gamma2 GABAA receptors drastically alter the affinity for ligands of the benzodiazepine binding site.
The Journal of biological chemistry 1997;272(18):11799-804.
1997: K Kannenberg; Roland Baur; Erwin Sigel
Proteins associated with alpha 1-subunit-containing GABAA receptors from bovine brain.
Journal of neurochemistry 1997;68(4):1352-60.
1996: Erwin Sigel; K Kannenberg
GABAA-receptor subtypes.
Trends in neurosciences 1996;19(9):386.
1996: Andreas Buhr; Roland Baur; Pari Malherbe; Erwin Sigel
Point mutations of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid(A) receptor affecting modulation of the channel by ligands of the benzodiazepine binding site.
Molecular pharmacology 1996;49(6):1080-4.
1996: S Kellenberger; S Eckenstein; Roland Baur; Pari Malherbe; Andreas Buhr; Erwin Sigel
Subunit stoichiometry of oligomeric membrane proteins: GABAA receptors isolated by selective immunoprecipitation from the cell surface.
Neuropharmacology 1996;35(9-10):1403-11.
1995: K Kannenberg; M H Groschup; Erwin Sigel
Cellular prion protein and GABAA receptors: no physical association?
Neuroreport 1995;7(1):77-80.
1995: Erwin Sigel
Functional modulation of ligand-gated GABAA and NMDA receptor channels by phosphorylation.
Journal of receptor and signal transduction research 1995;15(1-4):325-32.
1994: Erwin Sigel; Roland Baur; Pari Malherbe
Protein kinase C transiently activated heteromeric N-methyl-D-aspartate receptor channels independent of the phosphorylatable C-terminal splice domain and of consensus phosphorylation sites.
The Journal of biological chemistry 1994;269(11):8204-8.
1993: Erwin Sigel; Roland Baur; Pari Malherbe
Recombinant GABAA receptor function and ethanol.
FEBS letters 1993;324(2):140-2.
1992: S Kellenberger; Pari Malherbe; Erwin Sigel
Function of the alpha 1 beta 2 gamma 2S gamma-aminobutyric acid type A receptor is modulated by protein kinase C via multiple phosphorylation sites.
The Journal of biological chemistry 1992;267(36):25660-3.
1992: Erwin Sigel; Roland Baur; S Kellenberger; Pari Malherbe
Point mutations affecting antagonist affinity and agonist dependent gating of GABAA receptor channels.
The EMBO journal 1992;11(6):2017-23.
1991: F Knoflach; T Rhyner; M Villa; S Kellenberger; U Drescher; Pari Malherbe; Erwin Sigel; H Möhler
The gamma 3-subunit of the GABAA-receptor confers sensitivity to benzodiazepine receptor ligands.
FEBS letters 1991;293(1-2):191-4.
1991: Erwin Sigel; Roland Baur; Pari Malherbe
Activation of protein kinase C results in down-modulation of different recombinant GABAA-channels.
FEBS letters 1991;291(1):150-2.
1991: A B Peter; Johannes C Schittny; Verena Niggli; H Reuter; Erwin Sigel
The polarized distribution of poly(A+)-mRNA-induced functional ion channels in the Xenopus oocyte plasma membrane is prevented by anticytoskeletal drugs.
The Journal of cell biology 1991;114(3):455-64.
1991: H Reuter; Erwin Sigel
Ionic channels: modulation by G proteins and by phosphorylation.
Current opinion in neurobiology 1991;1(1):27-31.
1990: Erwin Sigel; Roland Baur; Gerhard Trube; H Möhler; Pari Malherbe
The effect of subunit composition of rat brain GABAA receptors on channel function.
Neuron 1990;5(5):703-11.
1990: Erwin Sigel
Use of Xenopus oocytes for the functional expression of plasma membrane proteins.
The Journal of membrane biology 1990;117(3):201-21.
1990: Pari Malherbe; Erwin Sigel; Roland Baur; E Persohn; J Grayson Richards; Hanns Mohler
Functional characteristics and sites of gene expression of the alpha 1, beta 1, gamma 2-isoform of the rat GABAA receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(7):2330-7.
1990: Erwin Sigel
Dangers of 'single-point pharmacology' in receptor studies. GABAA receptor: complex picture confused.
Trends in pharmacological sciences 1990;11(3):103.
1990: Pari Malherbe; Erwin Sigel; Roland Baur; E Persohn; J Grayson Richards; H Möhler
Functional expression and sites of gene transcription of a novel alpha subunit of the GABAA receptor in rat brain.
FEBS letters 1990;260(2):261-5.
1990: Hanns Mohler; Pari Malherbe; A Draguhn; Erwin Sigel; J M Sequier; E Persohn; J Grayson Richards
GABAA-receptor subunits: functional expression and gene localisation.
Advances in biochemical psychopharmacology 1990;46():23-34.
1989: Erwin Sigel; Roland Baur; Pari Malherbe; H Möhler
The rat beta 1-subunit of the GABAA receptor forms a picrotoxin-sensitive anion channel open in the absence of GABA.
FEBS letters 1989;257(2):377-9.
1989: Y Yao; A B Peter; Roland Baur; Erwin Sigel
The tremorigen aflatrem is a positive allosteric modulator of the gamma-aminobutyric acidA receptor channel expressed in Xenopus oocytes.
Molecular pharmacology 1989;35(3):319-23.
1988: Erwin Sigel; Roland Baur; Hartmut Porzig; H Reuter
mRNA-induced expression of the cardiac Na+-Ca2+ exchanger in Xenopus oocytes.
The Journal of biological chemistry 1988;263(29):14614-6.
1988: Erwin Sigel; Roland Baur
Activation of protein kinase C differentially modulates neuronal Na+, Ca2+, and gamma-aminobutyrate type A channels.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(16):6192-6.
1988: Erwin Sigel; Roland Baur
Allosteric modulation by benzodiazepine receptor ligands of the GABAA receptor channel expressed in Xenopus oocytes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(1):289-95.
1987: Erwin Sigel; Roland Baur
Effect of avermectin B1a on chick neuronal gamma-aminobutyrate receptor channels expressed in Xenopus oocytes.
Molecular pharmacology 1987;32(6):749-52.
1987: Erwin Sigel
Effects of veratridine on single neuronal sodium channels expressed in Xenopus oocytes.
Pflügers Archiv : European journal of physiology 1987;410(1-2):112-20.
1987: Erwin Sigel
Properties of single sodium channels translated by Xenopus oocytes after injection with messenger ribonucleic acid.
The Journal of physiology 1987;386():73-90.
1987: Erwin Sigel; H Affolter
Preparation and utilization of an ion-specific calcium minielectrode.
Methods in enzymology 1987;141():25-36.
1985: Erwin Sigel; C Mamalaki; Eric A Barnard
Reconstitution of the purified gamma-aminobutyric acid-benzodiazepine receptor complex from bovine cerebral cortex into phospholipid vesicles.
Neuroscience letters 1985;61(1-2):165-70.
1984: Erwin Sigel; E A Barnard
A gamma-aminobutyric acid/benzodiazepine receptor complex from bovine cerebral cortex. Improved purification with preservation of regulatory sites and their interactions.
The Journal of biological chemistry 1984;259(11):7219-23.
1984: Erwin Sigel; F Anne Stephenson; C Mamalaki; Eric A Barnard
The purified GABA/benzodiazepine/barbiturate receptor complex: four types of ligand-binding sites, and the interactions between them, are preserved in a single isolated protein complex.
Journal of receptor research 1984;4(1-6):175-88.
1984: Eric A Barnard; F Anne Stephenson; Erwin Sigel; C Mamalaki; G Bilbe; A Constanti; T G Smart; D A Brown
Structure and properties of the brain GABA/benzodiazepine receptor complex.
Advances in experimental medicine and biology 1984;175():235-54.
1983: Erwin Sigel; F Anne Stephenson; C Mamalaki; Eric A Barnard
A gamma-aminobutyric acid/benzodiazepine receptor complex of bovine cerebral cortex.
The Journal of biological chemistry 1983;258(11):6965-71.
1982: Erwin Sigel; C Mamalaki; Eric A Barnard
Isolation of a GABA receptor from bovine brain using a benzodiazepine affinity column.
FEBS letters 1982;147(1):45-8.
1982: Verena Niggli; Erwin Sigel; E Carafoli
The purified Ca2+ pump of human erythrocyte membranes catalyzes an electroneutral Ca2+-H+ exchange in reconstituted liposomal systems.
The Journal of biological chemistry 1982;257(5):2350-6.
1982: Verena Niggli; Erwin Sigel; E Carafoli
Inhibition of the purified and reconstituted calcium pump of erythrocytes by micro M levels of DIDS and NAP-taurine.
FEBS letters 1982;138(2):164-6.
1981: S Kawato; Erwin Sigel; E Carafoli; R J Cherry
Rotation of cytochrome oxidase in phospholipid vesicles. Investigations of interactions between cytochrome oxidases and between cytochrome oxidase and cytochrome bc1 complex.
The Journal of biological chemistry 1981;256(14):7518-27.
1980: Erwin Sigel; E Carafoli
Quantitative analysis of the proton and charge stoichiometry of cytochrome c oxidase from beef heart reconstituted into phospholipid vesicles.
European journal of biochemistry / FEBS 1980;111(2):299-306.
1980: S Kawato; Erwin Sigel; E Carafoli; R J Cherry
Cytochrome oxidase rotates in the inner membrane of intact mitochondria and submitochondrial particles.
The Journal of biological chemistry 1980;255(12):5508-10.
1979: Erwin Sigel; E Carafoli
The charge stoichiometry of cytochrome c oxidase in the reconstituted system.
The Journal of biological chemistry 1979;254(21):10572-4.
1979: H Affolter; Erwin Sigel
A simple system for the measurement of ion activities with solvent polymeric membrane electrodes.
Analytical biochemistry 1979;97(2):315-9.
1978: Erwin Sigel; E Carafoli
The proton pump of cytochrome c oxidase and its stoichiometry.
European journal of biochemistry / FEBS 1978;89(1):119-23.
1976: E Carafoli; K Malmström; Erwin Sigel; M Crompton
The regulation of intracellular calcium.
Clinical endocrinology 1976;5 Suppl():49S-59S.