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Joost Lensen

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Mabel van den Hoven; Tessa J M Wijnhoven; J-P Li; E Zcharia; Henry B P M Dijkman; Ronnie G P Wismans; Angelique L W M M Rops; Joost Lensen; Lambert P van den Heuvel; Toin H van Kuppevelt; Israel Vlodavsky; Jo H M Berden; Johan Van der Vlag
Reduction of anionic sites in the glomerular basement membrane by heparanase does not lead to proteinuria.
Tessa J M Wijnhoven; Els M A van de Westerlo; Nicole Smits; Joost Lensen; Angelique L W M M Rops; Johan Van der Vlag; Jo H M Berden; Lambert P van den Heuvel; Toin H van Kuppevelt
Characterization of anticoagulant heparinoids by immunoprofiling.
Angelique L W M M Rops; Mabel van den Hoven; M M Baselmans; Joost Lensen; Tessa J M Wijnhoven; Lambert P van den Heuvel; Toin H van Kuppevelt; Jo H M Berden; Johan Van der Vlag
Heparan sulfate domains on cultured activated glomerular endothelial cells mediate leukocyte trafficking.

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All Publications

2008: Mabel van den Hoven; Tessa J M Wijnhoven; J-P Li; E Zcharia; Henry B P M Dijkman; Ronnie G P Wismans; Angelique L W M M Rops; Joost Lensen; Lambert P van den Heuvel; Toin H van Kuppevelt; Israel Vlodavsky; Jo H M Berden; Johan Van der Vlag
Reduction of anionic sites in the glomerular basement membrane by heparanase does not lead to proteinuria.
Kidney international 2008;73(3):278-87.
2008: Tessa J M Wijnhoven; Els M A van de Westerlo; Nicole Smits; Joost Lensen; Angelique L W M M Rops; Johan Van der Vlag; Jo H M Berden; Lambert P van den Heuvel; Toin H van Kuppevelt
Characterization of anticoagulant heparinoids by immunoprofiling.
Glycoconjugate journal 2008;25(2):177-85.
2008: Angelique L W M M Rops; Mabel van den Hoven; M M Baselmans; Joost Lensen; Tessa J M Wijnhoven; Lambert P van den Heuvel; Toin H van Kuppevelt; Jo H M Berden; Johan Van der Vlag
Heparan sulfate domains on cultured activated glomerular endothelial cells mediate leukocyte trafficking.
Kidney international 2008;73(1):52-62.
2007: Tessa J M Wijnhoven; Joost Lensen; Ronnie G P Wismans; Dirk J Lefeber; Angelique L W M M Rops; Johan Van der Vlag; Jo H M Berden; Lambert P van den Heuvel; Toin H van Kuppevelt
Removal of heparan sulfate from the glomerular basement membrane blocks protein passage.
Journal of the American Society of Nephrology : JASN 2007;18(12):3119-27.
2007: Angelique L W M M Rops; Martin Götte; M H Baselmans; Mabel van den Hoven; Eric J Steenbergen; Joost Lensen; Tessa J M Wijnhoven; F Cevikbas; Lambert P van den Heuvel; Toin H van Kuppevelt; Jo H M Berden; Johan Van der Vlag
Syndecan-1 deficiency aggravates anti-glomerular basement membrane nephritis.
Kidney international 2007;72(10):1204-15.
2007: Tessa J M Wijnhoven; Joyce M Geelen; Marinka Bakker; Joost Lensen; Angelique L W M M Rops; Andrea B Kramer; gerjan navis; Mabel van den Hoven; Johan Van der Vlag; Jo H M Berden; Jack F M Wetzels; Lambert P van den Heuvel; Leo A H Monnens; Toin H van Kuppevelt
Adult and paediatric patients with minimal change nephrotic syndrome show no major alterations in glomerular expression of sulphated heparan sulphate domains.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(10):2886-93.
2007: Tessa J M Wijnhoven; Joost Lensen; Angelique L W M M Rops; Kevin J Mccarthy; Johan Van der Vlag; Jo H M Berden; Lambert P van den Heuvel; Toin H van Kuppevelt
Anti-proteinuric effects of glycosaminoglycan-based drugs.
Current opinion in molecular therapeutics 2007;9(4):364-77.
2007: Angelique L W M M Rops; Mabel van den Hoven; Marinka A H Bakker; Joost Lensen; Tessa J M Wijnhoven; Lambert P van den Heuvel; Toin H van Kuppevelt; Johan Van der Vlag; Jo H M Berden
Expression of glomerular heparan sulphate domains in murine and human lupus nephritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(7):1891-902.
2007: Angelique L W M M Rops; Cor W Jacobs; Peter C Linssen; Jan B M Boezeman; Joost Lensen; Tessa J M Wijnhoven; Lambert P van den Heuvel; Toin H van Kuppevelt; Johan Van der Vlag; Jo H M Berden
Heparan sulfate on activated glomerular endothelial cells and exogenous heparinoids influence the rolling and adhesion of leucocytes.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(4):1070-7.
2007: Tessa J M Wijnhoven; Joost Lensen; Ronnie G P Wismans; Mohammed Lamrani; Leo A H Monnens; Ron A Wevers; Angelique L W M M Rops; Johan Van der Vlag; Jo H M Berden; Lambert P van den Heuvel; Toin H van Kuppevelt
In vivo degradation of heparan sulfates in the glomerular basement membrane does not result in proteinuria.
Journal of the American Society of Nephrology : JASN 2007;18(3):823-32.
2006: Joost Lensen; Tessa J M Wijnhoven; Leon H Kuik; Elly M M Versteeg; Theo Hafmans; Angelique L W M M Rops; M S G Pavao; Johan Van der Vlag; Lambert P van den Heuvel; Jo H M Berden; Toin H van Kuppevelt
Selection and characterization of a unique phage display-derived antibody against dermatan sulfate.
Matrix biology : journal of the International Society for Matrix Biology 2006;25(7):457-61.
2006: Andrea Kramer; Mabel van den Hoven; Angelique L W M M Rops; Tessa J M Wijnhoven; Lambert van Den Heuvel; Joost Lensen; Toin H van Kuppevelt; Harry van Goor; Johan Van der Vlag; gerjan navis; Jo H M Berden
Induction of glomerular heparanase expression in rats with adriamycin nephropathy is regulated by reactive oxygen species and the renin-angiotensin system.
Journal of the American Society of Nephrology : JASN 2006;17(9):2513-20.
2006: Tessa J M Wijnhoven; Joost Lensen; Angelique L W M M Rops; Johan Van der Vlag; Svein Olav Kolset; Hans-Jacob Bangstad; Per Pfeffer; Mabel van den Hoven; Jo H M Berden; Lambert P van den Heuvel; Toin H van Kuppevelt
Aberrant heparan sulfate profile in the human diabetic kidney offers new clues for therapeutic glycomimetics.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2006;48(2):250-61.
2006: Nicole Smits; Joost Lensen; Tessa J M Wijnhoven; Gerdy B ten Dam; Guido J Jenniskens; Toin H van Kuppevelt
Phage display-derived human antibodies against specific glycosaminoglycan epitopes.
Methods in enzymology 2006;416():61-87.
2005: Joost Lensen; Angelique L W M M Rops; Tessa J M Wijnhoven; Theo Hafmans; W F J Feitz; Egbert Oosterwijk; Bernhard Banas; René J M Bindels; Lambert P van den Heuvel; Johan Van der Vlag; Jo H M Berden; Toin H van Kuppevelt
Localization and functional characterization of glycosaminoglycan domains in the normal human kidney as revealed by phage display-derived single chain antibodies.
Journal of the American Society of Nephrology : JASN 2005;16(5):1279-88.
2004: Angelique L W M M Rops; Johan Van der Vlag; Cor W Jacobs; Henry B P M Dijkman; Joost Lensen; Tessa J M Wijnhoven; Lambert P van den Heuvel; Toin H van Kuppevelt; Jo H M Berden
Isolation and characterization of conditionally immortalized mouse glomerular endothelial cell lines.
Kidney international 2004;66(6):2193-201.
2004: Bart Smeets; Nathalie A J M te Loeke; Henry B P M Dijkman; Mark L M Steenbergen; Joost Lensen; Mark P V Begieneman; Toin H van Kuppevelt; Jack F M Wetzels; Eric J Steenbergen
The parietal epithelial cell: a key player in the pathogenesis of focal segmental glomerulosclerosis in Thy-1.1 transgenic mice.
Journal of the American Society of Nephrology : JASN 2004;15(4):928-39.
2004: Angelique L W M M Rops; Johan Van der Vlag; Joost Lensen; Tessa J M Wijnhoven; Lambert P van den Heuvel; Toin H van Kuppevelt; Jo H M Berden
Heparan sulfate proteoglycans in glomerular inflammation.
Kidney international 2004;65(3):768-85.
2003: Alwin Scharstuhl; Robin J W Diepens; Joost Lensen; Elly L Vitters; Henk M van Beuningen; Peter van der Kraan; Wim B van den Berg
Adenoviral overexpression of Smad-7 and Smad-6 differentially regulates TGF-beta-mediated chondrocyte proliferation and proteoglycan synthesis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2003;11(11):773-82.