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Arto Urtti

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Corey J Bishop; Tiia-Maaria Ketola; Helge Lemmetyinen; Joel C Sunshine; Stephany Y Tzeng; Arto Urtti; Elina Vuorimaa-Laukkanen; Marjo Yliperttula; Jordan J Green
The Effect and Role of Carbon Atoms in Poly(β-amino ester)s for DNA Binding and Gene Delivery.
Helka Juvonen; Patrick Laurén; Anni Määttänen; Arto Urtti; Marjo Yliperttula; Petri Ihalainen; Jouko Peltonen
Biocompatibility of printed paper-based arrays for 2-D cell cultures.
Janne Raula; Arto Urtti; Martina Hanzlíková; Juho Hautala; Esko I Kauppinen; Antti Rahikkala; Marjo Yliperttula
Gas-phase synthesis of solid state DNA nanoparticles stabilized by l-leucine.

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2013: Corey J Bishop; Tiia-Maaria Ketola; Helge Lemmetyinen; Joel C Sunshine; Stephany Y Tzeng; Arto Urtti; Elina Vuorimaa-Laukkanen; Marjo Yliperttula; Jordan J Green
The Effect and Role of Carbon Atoms in Poly(β-amino ester)s for DNA Binding and Gene Delivery.
Journal of the American Chemical Society 2013;135(18):6951-7.
2013: Helka Juvonen; Patrick Laurén; Anni Määttänen; Arto Urtti; Marjo Yliperttula; Petri Ihalainen; Jouko Peltonen
Biocompatibility of printed paper-based arrays for 2-D cell cultures.
Acta biomaterialia 2013;9(5):6704-10.
2013: Janne Raula; Arto Urtti; Martina Hanzlíková; Juho Hautala; Esko I Kauppinen; Antti Rahikkala; Marjo Yliperttula
Gas-phase synthesis of solid state DNA nanoparticles stabilized by l-leucine.
International journal of pharmaceutics 2013;444(1-2):155-61.
2013: Anton Kiselev; Antti Laukkanen; Vladislav Baranov; Anna Egorova; Arto Urtti
Characterization of reducible peptide oligomers as carriers for gene delivery.
International journal of pharmaceutics 2013;441(1-2):736-47.
2013: Marco G Casteleijn; Arto Urtti; Sanjay Sarkhel
Expression without boundaries: cell-free protein synthesis in pharmaceutical research.
International journal of pharmaceutics 2013;440(1):39-47.
2012: Madhushree Bhattacharya; Anne Corlu; Christiane Guguen-Guillouzo; Olli Ikkala; Liisa Kanninen; Saara W Kuisma; Antti Laukkanen; Patrick Lauren; Martina Lille; Yan-Ru Lou; Melina M Malinen; Arto Urtti; Marjo Yliperttula
Nanofibrillar cellulose hydrogel promotes three-dimensional liver cell culture.
Journal of controlled release : official journal of the Controlled Release Society 2012;164(3):291-8.
2012: Heidi Kidron; Eva M Del Amo; Kati-Sisko Vellonen; Arto Urtti
Prediction of the vitreal half-life of small molecular drug-like compounds.
Pharmaceutical research 2012;29(12):3302-11.
2012: Melina M Malinen; Harri Palokangas; Marjo Yliperttula; Arto Urtti
Peptide nanofiber hydrogel induces formation of bile canaliculi structures in three-dimensional hepatic cell culture.
Tissue engineering. Part A 2012;18(23-24):2418-25.
2012: Astrid Subrizi; Arto Urtti; Hannu Uusitalo; Marjo Yliperttula; Peter Dubruel; Hanna Hiidenmaa; Tanja Ilmarinen; Soile Nymark; Heli Skottman
Generation of hESC-derived retinal pigment epithelium on biopolymer coated polyimide membranes.
Biomaterials 2012;33(32):8047-54.
2012: Jonna Wikström; Matti Elomaa; Petteri Heljo; Laura Nevala; Johanna Räikkönen; Arto Urtti; Marjo Yliperttula
Viability of freeze dried microencapsulated human retinal pigment epithelial cells.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2012;47(2):520-6.
2012: Christa Nilsson; Arto Urtti; Jesper Ostergaard; Katarina Edwards; Jonny Eriksson; Claus Larsen; Susan Weng Larsen; Anan Yaghmur
Characterization of oil-free and oil-loaded liquid-crystalline particles stabilized by negatively charged stabilizer citrem.
Langmuir : the ACS journal of surfaces and colloids 2012;28(32):11755-66.
2012: Sari Pappinen; Evgeny Pryazhnikov; Marica B Ericson; Leonard Khiroug; Marjo Yliperttula; Arto Urtti
Organotypic cell cultures and two-photon imaging: tools for in vitro and in vivo assessment of percutaneous drug delivery and skin toxicity.
Journal of controlled release : official journal of the Controlled Release Society 2012;161(2):656-67.
2012: Julia Lehtinen; Aniket Magarkar; Tomasz Róg; Michał Stepniewski; Arto Urtti; Marjo Yliperttula; Mathias Bergman; Satu Hakola; alex bunker
Analysis of cause of failure of new targeting peptide in PEGylated liposome: molecular modeling as rational design tool for nanomedicine.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2012;46(3):121-30.
2012: Heidi Kidron; Nenad Manevski; Moshe Finel; Marika Häkli; Raimo A Ketola; Gloria Wissel; Henri Xhaard; Marjo Yliperttula; Arto Urtti
Impact of probe compound in MRP2 vesicular transport assays.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2012;46(1-2):100-5.
2012: Astrid Subrizi; Eva Tuominen; Maxim Antopolsky; alex bunker; Tomasz Róg; Arto Urtti
Tat(48-60) peptide amino acid sequence is not unique in its cell penetrating properties and cell-surface glycosaminoglycans inhibit its cellular uptake.
Journal of controlled release : official journal of the Controlled Release Society 2012;158(2):277-85.
2012: Yuuki Takashima; Tomohiro Tsuchiya; Yuko Igarashi; Takanori Kanazawa; Hiroaki Okada; Arto Urtti
[Non-invasive ophthalmic liposomes for nucleic acid delivery to posterior segment of eye].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2012;132(12):1365-70.
2012: Miia Pitkonen; Mari Raki; Mart Saarma; Sauli Savolainen; Arto Urtti; Jaan-Olle Andressoo; Eero Hippeläinen; Pekka T Männistö; Kim Bergström
Advanced brain dopamine transporter imaging in mice using small-animal SPECT/CT.
EJNMMI research 2012;2(1):55.
2012: Julia Lehtinen; Katariina Lehtinen; Huamin Liang; Ann-Marie Määttä; Jere Pikkarainen; Sari Pitkänen; Mari Raki; Kim A Bergström; Annukka Hiltunen; Raimo A Ketola; Päivi Uutela; Thomas Wirth; Marjo Yliperttula; Arto Urtti
Pre-targeting and direct immunotargeting of liposomal drug carriers to ovarian carcinoma.
PloS one 2012;7(7):e41410.
2012: Mika Reinisalo; Arto Urtti; Eliisa Mannermaa; Jaana Putula; Paavo Honkakoski
Regulation of the human tyrosinase gene in retinal pigment epithelium cells: the significance of transcription factor orthodenticle homeobox 2 and its polymorphic binding site.
Molecular vision 2012;18():38-54.
2011: Elina Vuorimaa; Daniel G Anderson; Jordan Green; Martina Hanzlíková; Tiia-Maaria Ketola; Robert Langer; Helge Lemmetyinen; Arto Urtti; Marjo Yliperttula
Poly(β-amino ester)-DNA complexes: time-resolved fluorescence and cellular transfection studies.
Journal of controlled release : official journal of the Controlled Release Society 2011;154(2):171-6.
2011: Martina Hanzlíková; Atso Raasmaja; Marika Ruponen; Heikki Tenhu; Arto Urtti; Vladimir Aseyev; Emilia Galli; Marjo Yliperttula
Mechanisms of polyethylenimine-mediated DNA delivery: free carrier helps to overcome the barrier of cell-surface glycosaminoglycans.
The journal of gene medicine 2011;13(7-8):402-9.
2011: Leena-Stiina Kontturi; Antti Määttä; Ann-Marie Määttä; Pyry Toivanen; Marjo Yliperttula; Arto Urtti
A laboratory-scale device for the straightforward production of uniform, small sized cell microcapsules with long-term cell viability.
Journal of controlled release : official journal of the Controlled Release Society 2011;152(3):376-81.
2011: Tiia-Maaria Ketola; Martina Hanzlíková; Arto Urtti; Helge Lemmetyinen; Marjo Yliperttula; Elina Vuorimaa
Role of polyplex intermediate species on gene transfer efficiency: polyethylenimine-DNA complexes and time-resolved fluorescence spectroscopy.
The journal of physical chemistry. B 2011;115(8):1895-902.
2011: Teemu Heikkilä; Milja Karjalainen; Krista Ojala; Kirsi Partola; Frank Lammert; Patrick Augustijns; Arto Urtti; Marjo Yliperttula; Leena Peltonen; Jouni Hirvonen
Equilibrium drug solubility measurements in 96-well plates reveal similar drug solubilities in phosphate buffer pH 6.8 and human intestinal fluid.
International journal of pharmaceutics 2011;405(1-2):132-6.
2010: Veli-Pekka Ranta; Eliisa Mannermaa; Kirsi Lummepuro; Astrid Subrizi; Antti Laukkanen; Maxim Antopolsky; Lasse Murtomäki; Margit Hornof; Arto Urtti
Barrier analysis of periocular drug delivery to the posterior segment.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):42-8.
2010: Lauri Paasonen; Tuomas Sipilä; Astrid Subrizi; Pasi Laurinmäki; Sarah J Butcher; Michael Rappolt; Anan Yaghmur; Arto Urtti; Marjo Yliperttula
Gold-embedded photosensitive liposomes for drug delivery: triggering mechanism and intracellular release.
Journal of controlled release : official journal of the Controlled Release Society 2010;147(1):136-43.
2010: Eliisa Mannermaa; Mika Reinisalo; Veli-Pekka Ranta; Kati-Sisko Vellonen; Hannu Kokki; Anni Saarikko; Kai Kaarniranta; Arto Urtti
Filter-cultured ARPE-19 cells as outer blood-retinal barrier model.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;40(4):289-96.
2010: Heidi Kidron; Kati-Sisko Vellonen; Eva M del Amo; Anita Tissari; Arto Urtti
Prediction of the corneal permeability of drug-like compounds.
Pharmaceutical research 2010;27(7):1398-407.
2010: Johanna Linnankoski; Johanna Mäkelä; Juni Palmgren; Timo Mauriala; Charlotta Vedin; Anna-Lena Ungell; Lucia Lazorova; Per Artursson; Arto Urtti; Marjo Yliperttula
Paracellular porosity and pore size of the human intestinal epithelium in tissue and cell culture models.
Journal of pharmaceutical sciences 2010;99(4):2166-75.
2010: Kati-Sisko Vellonen; Marika Häkli; Natalya Merezhinskaya; Timo Tervo; Paavo Honkakoski; Arto Urtti
Monocarboxylate transport in human corneal epithelium and cell lines.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;39(4):241-7.
2010: Kati-Sisko Vellonen; Eliisa Mannermaa; Helen Turner; Marika Häkli; J Mario Wolosin; Timo Tervo; Paavo Honkakoski; Arto Urtti
Effluxing ABC transporters in human corneal epithelium.
Journal of pharmaceutical sciences 2010;99(2):1087-98.
2010: Dario Greco; Kati-Sisko Vellonen; Helen C Turner; Marika Häkli; Timo Tervo; Petri Auvinen; J Mario Wolosin; Arto Urtti
Gene expression analysis in SV-40 immortalized human corneal epithelial cells cultured with an air-liquid interface.
Molecular vision 2010;16():2109-20.
2010: Zheng Wang; Peter S Reinach; Fan Zhang; Kati-Sisko Vellonen; Arto Urtti; Helen Turner; J Mario Wolosin
DUSP5 and DUSP6 modulate corneal epithelial cell proliferation.
Molecular vision 2010;16():1696-704.
2010: Johanna Viiri; Juha M T Hyttinen; Tuomas Ryhänen; Kirsi Rilla; Tuomas Paimela; Erkki Kuusisto; Ari Siitonen; Arto Urtti; Antero Salminen; Kai Kaarniranta
p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells.
Molecular vision 2010;16():1399-414.
2010: AI Soikkeli; Cristina Sempio; Ann Marie Kaukonen; Arto Urtti; Jouni Hirvonen; Marjo Yliperttula
Feasibility evaluation of 3 automated cellular drug screening assays on a robotic workstation.
Journal of biomolecular screening 2010;15(1):30-41.
2009: Anna Egorova; Anton Kiselev; Marika Hakli; Marika Ruponen; Vladislav Baranov; Arto Urtti
Chemokine-derived peptides as carriers for gene delivery to CXCR4 expressing cells.
The journal of gene medicine 2009;11(9):772-81.
2009: Eliisa Mannermaa; Kati-Sisko Vellonen; Tuomas Ryhänen; Katriina Kokkonen; Veli-Pekka Ranta; Kai Kaarniranta; Arto Urtti
Efflux protein expression in human retinal pigment epithelium cell lines.
Pharmaceutical research 2009;26(7):1785-91.
2009: Marika Ruponen; Satu Arkko; Arto Urtti; Mika Reinisalo; Veli-Pekka Ranta
Intracellular DNA release and elimination correlate poorly with transgene expression after non-viral transfection.
Journal of controlled release : official journal of the Controlled Release Society 2009;136(3):226-31.
2009: Anne Huhtala; Seppo Rönkkö; Markku Teräsvirta; Tuomo Puustjärvi; Roope Sihvola; Katja Vehanen; Antti Laukkanen; Johanna Anttila; Arto Urtti; Timo Pohjonen; Hannu Uusitalo
The effects of 5-fluorouracil on ocular tissues in vitro and in vivo after controlled release from a multifunctional implant.
Investigative ophthalmology & visual science 2009;50(5):2216-23.
2008: Marika Karskela; Pasi Virta; Melina Malinen; Arto Urtti; Harri Lönnberg
Synthesis and cellular uptake of fluorescently labeled multivalent hyaluronan disaccharide conjugates of oligonucleotide phosphorothioates.
Bioconjugate chemistry 2008;19(12):2549-58.
2008: Julia Lehtinen; Zanna Hyvönen; Astrid Subrizi; Heike Bunjes; Arto Urtti
Glycosaminoglycan-resistant and pH-sensitive lipid-coated DNA complexes produced by detergent removal method.
Journal of controlled release : official journal of the Controlled Release Society 2008;131(2):145-9.
2008: Eva M del Amo; Arto Urtti; Marjo Yliperttula
Pharmacokinetic role of L-type amino acid transporters LAT1 and LAT2.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;35(3):161-74.
2008: Marjo Yliperttula; Bong Geun Chung; Akshay Navaladi; Amir Manbachi; Arto Urtti
High-throughput screening of cell responses to biomaterials.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;35(3):151-60.
2008: Elina Vuorimaa; Arto Urtti; Raimo Seppänen; Helge Lemmetyinen; Marjo Yliperttula
Time-resolved fluorescence spectroscopy reveals functional differences of cationic polymer-DNA complexes.
Journal of the American Chemical Society 2008;130(35):11695-700.
2008: Johanna Linnankoski; Veli-Pekka Ranta; Marjo Yliperttula; Arto Urtti
Passive oral drug absorption can be predicted more reliably by experimental than computational models--fact or myth.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;34(2-3):129-39.
2008: Juhani Wikström; H Syväjärvi; Arto Urtti; Marjo Yliperttula
Kinetic simulation model of protein secretion and accumulation in the cell microcapsules.
The journal of gene medicine 2008;10(5):575-82.
2008: Judith Kuntsche; Heike Bunjes; Alfred Fahr; Sari Pappinen; Seppo Rönkkö; Marjukka Suhonen; Arto Urtti
Interaction of lipid nanoparticles with human epidermis and an organotypic cell culture model.
International journal of pharmaceutics 2008;354(1-2):180-95.
2008: Sari Pappinen; Martin Hermansson; Judith Kuntsche; Pentti Somerharju; Philip Wertz; Arto Urtti; Marjukka Suhonen
Comparison of rat epidermal keratinocyte organotypic culture (ROC) with intact human skin: lipid composition and thermal phase behavior of the stratum corneum.
Biochimica et biophysica acta 2008;1778(4):824-34.
2008: Jonna Wikström; Matti Elomaa; Heli Syväjärvi; Johanna Kuokkanen; Marjo Yliperttula; Paavo Honkakoski; Arto Urtti
Alginate-based microencapsulation of retinal pigment epithelial cell line for cell therapy.
Biomaterials 2008;29(7):869-76.
2008: Eva M Del Amo; Arto Urtti
Current and future ophthalmic drug delivery systems. A shift to the posterior segment.
Drug discovery today 2008;13(3-4):135-43.
2008: Katja Vehanen; Margit Hornof; Arto Urtti; Hannu Uusitalo
Peribulbar poloxamer for ocular drug delivery.
Acta ophthalmologica 2008;86(1):91-6.
2008: Margit Hornof; Maria de la Fuente; Marjut Hallikainen; Raija Tammi; Arto Urtti
Low molecular weight hyaluronan shielding of DNA/PEI polyplexes facilitates CD44 receptor mediated uptake in human corneal epithelial cells.
The journal of gene medicine 2008;10(1):70-80.
2007: Lauri Paasonen; Birgit Romberg; Gert Storm; Marjo Yliperttula; Arto Urtti; Wim E Hennink
Temperature-sensitive poly(N-(2-hydroxypropyl)methacrylamide mono/dilactate)-coated liposomes for triggered contents release.
Bioconjugate chemistry 2007;18(6):2131-6.
2007: Leena Pitkänen; Veli-Pekka Ranta; Hanna Moilanen; Arto Urtti
Binding of betaxolol, metoprolol and oligonucleotides to synthetic and bovine ocular melanin, and prediction of drug binding to melanin in human choroid-retinal pigment epithelium.
Pharmaceutical research 2007;24(11):2063-70.
2007: Lauri Paasonen; Timo Laaksonen; Christoffer Johans; Marjo Yliperttula; Kyösti Kontturi; Arto Urtti
Gold nanoparticles enable selective light-induced contents release from liposomes.
Journal of controlled release : official journal of the Controlled Release Society 2007;122(1):86-93.
2007: Mauri A Kostiainen; Géza R Szilvay; Julia Lehtinen; David K Smith; Markus B Linder; Arto Urtti; Olli Ikkala
Precisely defined protein-polymer conjugates: construction of synthetic DNA binding domains on proteins by using multivalent dendrons.
ACS nano 2007;1(2):103-13.
2007: Sanna Siissalo; Leena Laitinen; Maija Koljonen; Kati-Sisko Vellonen; Hanna Kortejärvi; Arto Urtti; Jouni Hirvonen; Ann Marie Kaukonen
Effect of cell differentiation and passage number on the expression of efflux proteins in wild type and vinblastine-induced Caco-2 cell lines.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2007;67(2):548-54.
2007: Marjo Männistö; Mika Reinisalo; Marika Ruponen; Paavo Honkakoski; Markku Tammi; Arto Urtti
Polyplex-mediated gene transfer and cell cycle: effect of carrier on cellular uptake and intracellular kinetics, and significance of glycosaminoglycans.
The journal of gene medicine 2007;9(6):479-87.
2007: Elisa Toropainen; Margit Hornof; Kai Kaarniranta; Pinja Johansson; Arto Urtti
Corneal epithelium as a platform for secretion of transgene products after transfection with liposomal gene eyedrops.
The journal of gene medicine 2007;9(3):208-16.
2007: Sari Pappinen; Sanna Tikkinen; Sanna Pasonen-Seppänen; Lasse Murtomäki; Marjukka Suhonen; Arto Urtti
Rat epidermal keratinocyte organotypic culture (ROC) compared to human cadaver skin: the effect of skin permeation enhancers.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2007;30(3-4):240-50.
2007: Hanna Kortejärvi; Arto Urtti; Marjo Yliperttula
Pharmacokinetic simulation of biowaiver criteria: the effects of gastric emptying, dissolution, absorption and elimination rates.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2007;30(2):155-66.
2007: Eliisa Mannermaa; Arto Urtti; Kai Kaarniranta
[Not Available].
Duodecim; lääketieteellinen aikakauskirja 2007;123(18):2229-37.
2006: Peter Dubruel; Arto Urtti; Etienne Schacht
Surface plasmon resonance as an elegant technique to study polyplex-GAG interactions.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):e77-9.
2006: I Swennen; V Vermeersch; Margit Hornof; Els Adriaens; Jean Paul Remon; Arto Urtti; Etienne Schacht
In-situ crosslinkable thermo-responsive hydrogels for drug delivery.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):e21-4.
2006: Arto Urtti
Challenges and obstacles of ocular pharmacokinetics and drug delivery.
Advanced drug delivery reviews 2006;58(11):1131-5.
2006: Eliisa Mannermaa; Kati-Sisko Vellonen; Arto Urtti
Drug transport in corneal epithelium and blood-retina barrier: emerging role of transporters in ocular pharmacokinetics.
Advanced drug delivery reviews 2006;58(11):1136-63.
2006: Veli-Pekka Ranta; Arto Urtti
Transscleral drug delivery to the posterior eye: prospects of pharmacokinetic modeling.
Advanced drug delivery reviews 2006;58(11):1164-81.
2006: Hanna Kortejärvi; J Malkki; M Marvola; Arto Urtti; Marjo Yliperttula; P Pajunen
Level A in vitro-in vivo correlation (IVIVC) model with Bayesian approach to formulation series.
Journal of pharmaceutical sciences 2006;95(7):1595-605.
2006: Johanna Linnankoski; Johanna M Mäkelä; Veli-Pekka Ranta; Arto Urtti; Marjo Yliperttula
Computational prediction of oral drug absorption based on absorption rate constants in humans.
Journal of medicinal chemistry 2006;49(12):3674-81.
2006: Lauri Paasonen; Maarit Korhonen; Marjo Yliperttula; Arto Urtti
Epidermal cell culture model with tight stratum corneum as a tool for dermal gene delivery studies.
International journal of pharmaceutics 2006;307(2):188-93.
2006: Mika Reinisalo; Arto Urtti; Paavo Honkakoski
Freeze-drying of cationic polymer DNA complexes enables their long-term storage and reverse transfection of post-mitotic cells.
Journal of controlled release : official journal of the Controlled Release Society 2006;110(2):437-43.
2005: Sari Pappinen; Sanna Pasonen-Seppänen; Marjukka Suhonen; Raija Tammi; Arto Urtti
Rat epidermal keratinocyte organotypic culture (ROC) as a model for chemically induced skin irritation testing.
Toxicology and applied pharmacology 2005;208(3):233-41.
2005: Margit Hornof; Elisa Toropainen; Arto Urtti
Cell culture models of the ocular barriers.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2005;60(2):207-25.
2005: Eliisa Mannermaa; Seppo Rönkkö; Marika Ruponen; Mika Reinisalo; Arto Urtti
Long-lasting secretion of transgene product from differentiated and filter-grown retinal pigment epithelial cells after nonviral gene transfer.
Current eye research 2005;30(5):345-53.
2005: Marjo Männistö; Seppo Rönkkö; Mikko Mättö; Paavo Honkakoski; Mika M Hyttinen; Jukka Pelkonen; Arto Urtti
The role of cell cycle on polyplex-mediated gene transfer into a retinal pigment epithelial cell line.
The journal of gene medicine 2005;7(4):466-76.
2005: Leena Pitkänen; Veli-Pekka Ranta; Hanna Moilanen; Arto Urtti
Permeability of retinal pigment epithelium: effects of permeant molecular weight and lipophilicity.
Investigative ophthalmology & visual science 2005;46(2):641-6.
2005: Marika Ruponen; Zanna Hyvönen; Arto Urtti; Seppo Ylä-Herttuala
Nonviral gene delivery methods in cardiovascular diseases.
Methods in molecular medicine 2005;108():315-28.
2004: Sanna Hakkarainen; Anna-Kaisa Kontturi; Kyösti Kontturi; Arto Urtti
Electrochemical and calorimetric study of oligonucleotide complexation with cetylpyridinium chloride.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;23(4-5):371-7.
2004: Pasi Lampela; Päivi Soininen; Katja A Puttonen; Marika Ruponen; Arto Urtti; Pekka T Männistö; Atso Raasmaja
Effect of cell-surface glycosaminoglycans on cationic carrier combined with low-MW PEI-mediated gene transfection.
International journal of pharmaceutics 2004;284(1-2):43-52.
2004: Kati-Sisko Vellonen; Paavo Honkakoski; Arto Urtti
Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;23(2):181-8.
2004: Zanna Hyvönen; Seppo Rönkkö; Marjo-Riitta Toppinen; Ilpo Jääskeläinen; Aiva Plotniece; Arto Urtti
Dioleoyl phosphatidylethanolamine and PEG-lipid conjugates modify DNA delivery mediated by 1,4-dihydropyridine amphiphiles.
Journal of controlled release : official journal of the Controlled Release Society 2004;99(1):177-90.
2004: Annika Mälkiä; Lasse Murtomäki; Arto Urtti; Kyösti Kontturi
Drug permeation in biomembranes: in vitro and in silico prediction and influence of physicochemical properties.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;23(1):13-47.
2004: Laura Tuovinen; Eija Ruhanen; Tarja Kinnarinen; Seppo Rönkkö; Jukka Pelkonen; Arto Urtti; Soili Peltonen; Kristiina Järvinen
Starch acetate microparticles for drug delivery into retinal pigment epithelium-in vitro study.
Journal of controlled release : official journal of the Controlled Release Society 2004;98(3):407-13.
2004: Marika Ruponen; Paavo Honkakoski; Markku Tammi; Arto Urtti
Cell-surface glycosaminoglycans inhibit cation-mediated gene transfer.
The journal of gene medicine 2004;6(4):405-14.
2004: Ossi Korhonen; Hanna Kanerva; Mika Vidgren; Arto Urtti; Jarkko Ketolainen
Evaluation of novel starch acetate-diltiazem controlled release tablets in healthy human volunteers.
Journal of controlled release : official journal of the Controlled Release Society 2004;95(3):515-20.
2004: Pasi Lampela; Päivi Soininen; Arto Urtti; Pekka T Männistö; Atso Raasmaja
Synergism in gene delivery by small PEIs and three different nonviral vectors.
International journal of pharmaceutics 2004;270(1-2):175-84.
2004: Leena Pitkänen; Jukka Pelkonen; Marika Ruponen; Seppo Rönkkö; Arto Urtti
Neural retina limits the nonviral gene transfer to retinal pigment epithelium in an in vitro bovine eye model.
The AAPS journal 2004;6(3):e25.
2004: Ilpo Jääskeläinen; Katriina Lappalainen; Paavo Honkakoski; Arto Urtti
Requirements for delivery of active antisense oligonucleotides into cells with lipid carriers.
Methods in enzymology 2004;387():210-30.
2003: Marika Ruponen; Paavo Honkakoski; Seppo Rönkkö; Jukka Pelkonen; Markku Tammi; Arto Urtti
Extracellular and intracellular barriers in non-viral gene delivery.
Journal of controlled release : official journal of the Controlled Release Society 2003;93(2):213-7.
2003: Veli-Pekka Ranta; Mirka Laavola; Elisa Toropainen; Kati-Sisko Vellonen; Anu Talvitie; Arto Urtti
Ocular pharmacokinetic modeling using corneal absorption and desorption rates from in vitro permeation experiments with cultured corneal epithelial cells.
Pharmaceutical research 2003;20(9):1409-16.
2003: T Marjukka Suhonen; Sanna Pasonen-Seppänen; Merja Kirjavainen; Markku Tammi; Raija Tammi; Arto Urtti
Epidermal cell culture model derived from rat keratinocytes with permeability characteristics comparable to human cadaver skin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2003;20(1):107-13.
2003: Elisa Toropainen; Veli-Pekka Ranta; Kati-Sisko Vellonen; Joni J Palmgrén; Anu Talvitie; Mirka Laavola; Pekka Suhonen; Kaisa Mari Hämäläinen; Seppo Auriola; Arto Urtti
Paracellular and passive transcellular permeability in immortalized human corneal epithelial cell culture model.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2003;20(1):99-106.
2003: Peter Dubruel; Luc Dekie; Bart Christiaens; Berlinda Vanloo; Maryvonne Rosseneu; Joel Van De Kerckhove; Marjo Mannisto; Arto Urtti; Etienne Schacht
Poly-l-glutamic acid derivatives as multifunctional vectors for gene delivery. Part B. Biological evaluation.
Biomacromolecules 2003;4(5):1177-83.
2003: Mika Reinisalo; Arto Urtti; Paavo Honkakoski
Retina-specific gene expression and improved DNA transfection in WERI-Rb1 retinoblastoma cells.
Biochimica et biophysica acta 2003;1628(3):169-76.
2003: Leena Pitkänen; Marika Ruponen; Jenni Nieminen; Arto Urtti
Vitreous is a barrier in nonviral gene transfer by cationic lipids and polymers.
Pharmaceutical research 2003;20(4):576-83.
2003: S Peltola; P Saarinen-Savolainen; Juha Kiesvaara; TM Suhonen; Arto Urtti
Microemulsions for topical delivery of estradiol.
International journal of pharmaceutics 2003;254(2):99-107.
2003: Pasi Lampela; Matti Elomaa; Marika Ruponen; Arto Urtti; Pekka T Männistö; Atso Raasmaja
Different synergistic roles of small polyethylenimine and Dosper in gene delivery.
Journal of controlled release : official journal of the Controlled Release Society 2003;88(1):173-83.
2002: Joni J Palmgrén; Elisa Toropainen; Seppo Auriola; Arto Urtti
Liquid chromatographic-electrospray ionization mass spectrometric analysis of neutral and charged polyethylene glycols.
Journal of chromatography. A 2002;976(1-2):165-70.
2002: Marjo Männistö; Sylvie Vanderkerken; Veska Toncheva; Matti Elomaa; Marika Ruponen; Etienne Schacht; Arto Urtti
Structure-activity relationships of poly(L-lysines): effects of pegylation and molecular shape on physicochemical and biological properties in gene delivery.
Journal of controlled release : official journal of the Controlled Release Society 2002;83(1):169-82.
2002: Ilpo Jääskeläinen; Arto Urtti
Cell membranes as barriers for the use of antisense therapeutic agents.
Mini reviews in medicinal chemistry 2002;2(4):307-18.
2002: Zanna Hyvönen; Marika Ruponen; Seppo Rönkkö; Pekka Suhonen; Arto Urtti
Extracellular and intracellular factors influencing gene transfection mediated by 1,4-dihydropyridine amphiphiles.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2002;15(5):449-60.
2002: Veli-Pekka Ranta; Elisa Toropainen; Anu Talvitie; Seppo Auriola; Arto Urtti
Simultaneous determination of eight beta-blockers by gradient high-performance liquid chromatography with combined ultraviolet and fluorescence detection in corneal permeability studies in vitro.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2002;772(1):81-7.
2002: Anna-Kaisa Kontturi; Kyösti Kontturi; Arto Urtti
Conformation and ion-binding of oligonucleotides.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2002;15(4):379-85.
2002: Krista Laine; Kristiina Järvinen; David W Pate; Arto Urtti; Tomi Järvinen
Effect of the enzyme inhibitor, phenylmethylsulfonyl fluoride, on the IOP profiles of topical anandamides.
Investigative ophthalmology & visual science 2002;43(2):393-7.
2002: Ilpo Jääskeläinen; Paavo Honkakoski; Arto Urtti
In vitro delivery of antisense oligonucleotides.
Cellular & molecular biology letters 2002;7(2):236-7.
2001: Sanna Pasonen-Seppänen; TM Suhonen; Merja Kirjavainen; M Miettinen; Arto Urtti; Markku Tammi; Raija Tammi
Formation of permeability barrier in epidermal organotypic culture for studies on drug transport.
The Journal of investigative dermatology 2001;117(5):1322-4.
2001: Elisa Toropainen; Veli-Pekka Ranta; Anu Talvitie; Pekka Suhonen; Arto Urtti
Culture model of human corneal epithelium for prediction of ocular drug absorption.
Investigative ophthalmology & visual science 2001;42(12):2942-8.
2001: Sanna Pasonen-Seppänen; TM Suhonen; Merja Kirjavainen; Eero Suihko; Arto Urtti; M Miettinen; Mika M Hyttinen; Markku Tammi; Raija Tammi
Vitamin C enhances differentiation of a continuous keratinocyte cell line (REK) into epidermis with normal stratum corneum ultrastructure and functional permeability barrier.
Histochemistry and cell biology 2001;116(4):287-97.
2001: Marika Ruponen; Seppo Rönkkö; Paavo Honkakoski; Jukka Pelkonen; Markku Tammi; Arto Urtti
Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes.
The Journal of biological chemistry 2001;276(36):33875-80.
2001: Paavo Honkakoski; Ilpo Jääskeläinen; M Kortelahti; Arto Urtti
A novel drug-regulated gene expression system based on the nuclear receptor constitutive androstane receptor (CAR).
Pharmaceutical research 2001;18(2):146-50.
2001: Arto Urtti; Susan J Johns; Wolfgang Sadée
Genomic structure of proton-coupled oligopeptide transporter hPEPT1 and pH-sensing regulatory splice variant.
AAPS pharmSci 2001;3(1):E6.
2000: Zanna Hyvönen; A Plotniece; I Reine; B Chekavichus; Gunars Duburs; Arto Urtti
Novel cationic amphiphilic 1,4-dihydropyridine derivatives for DNA delivery.
Biochimica et biophysica acta 2000;1509(1-2):451-66.
2000: R Valjakka-Koskela; J Hirvonen; Jukka Mönkkönen; Juha Kiesvaara; Saila Antila; Lasse Lehtonen; Arto Urtti
Transdermal delivery of levosimendan.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;11(4):343-50.
2000: T Jaskari; Marja Vuorio; Kyösti Kontturi; Arto Urtti; José A Manzanares; Jouni Hirvonen
Controlled transdermal iontophoresis by ion-exchange fiber.
Journal of controlled release : official journal of the Controlled Release Society 2000;67(2-3):179-90.
2000: Riitta Sutinen; Timo Petteri Paronen; Veijo Saano; Arto Urtti
Water-activated, pH-controlled patch in transdermal administration of timolol. II. Drug absorption and skin irritation.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;11(1):25-31.
2000: Riitta Sutinen; Timo Petteri Paronen; Arto Urtti
Water-activated, pH-controlled patch in transdermal administration of timolol. I. Preclinical tests.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;11(1):19-24.
2000: Ilpo Jääskeläinen; S Peltola; Paavo Honkakoski; Jukka Mönkkönen; Arto Urtti
A lipid carrier with a membrane active component and a small complex size are required for efficient cellular delivery of anti-sense phosphorothioate oligonucleotides.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;10(3):187-93.
2000: Arto Urtti
Oligonucleotide theme.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;10(3):167.
2000: Merja Kirjavainen; Arto Urtti; Jukka Mönkkönen; Jouni Hirvonen
Influence of lipids on the mannitol flux during transdermal iontophoresis in vitro.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;10(2):97-102.
2000: Arto Urtti; JR Polansky; G M Lui; Francis Szoka, jr
Gene delivery and expression in human retinal pigment epithelial cells: effects of synthetic carriers, serum, extracellular matrix and viral promoters.
Journal of drug targeting 2000;7(6):413-21.
2000: Kaisa Mari Hämäläinen; Veli-Pekka Ranta; Seppo Auriola; Arto Urtti
Enzymatic and permeation barrier of [D-Ala(2)]-Met-enkephalinamide in the anterior membranes of the albino rabbit eye.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;9(3):265-70.
1999: Hanna Kanerva; O Kilkku; Antti Helminen; Juha Rouru; Mika Scheinin; Risto Huupponen; Imre Klebovich; Sándor Drabant; Arto Urtti
Pharmacokinetics and safety of deramciclane during multiple oral dosing.
International journal of clinical pharmacology and therapeutics 1999;37(12):589-97.
1999: Hanna Kanerva; O Kilkku; EH Heinonen; Antti Helminen; Juha Rouru; S Tarpila; Mika Scheinin; Risto Huupponen; Imre Klebovich; Sándor Drabant; Arto Urtti
The single dose pharmacokinetics and safety of deramciclane in healthy male volunteers.
Biopharmaceutics & drug disposition 1999;20(7):327-34.
1999: Maxim Antopolsky; Elena Azhayeva; Unni Tengvall; Seppo Auriola; Ilpo Jääskeläinen; Seppo Rönkkö; Paavo Honkakoski; Arto Urtti; Harri Lönnberg; Alex Azhayev
Peptide-oligonucleotide phosphorothioate conjugates with membrane translocation and nuclear localization properties.
Bioconjugate chemistry 1999;10(4):598-606.
1999: T Marjukka Suhonen; J A Bouwstra; Arto Urtti
Chemical enhancement of percutaneous absorption in relation to stratum corneum structural alterations.
Journal of controlled release : official journal of the Controlled Release Society 1999;59(2):149-61.
1999: N Makkonen; A Salminen; Michael J Rogers; Julie Crockett; Arto Urtti; Elena Azhayeva; Jukka Mönkkönen
Contrasting effects of alendronate and clodronate on RAW 264 macrophages: the role of a bisphosphonate metabolite.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 1999;8(2):109-18.
1999: Merja Kirjavainen; Jukka Mönkkönen; M Saukkosaari; R Valjakka-Koskela; Juha Kiesvaara; Arto Urtti
Phospholipids affect stratum corneum lipid bilayer fluidity and drug partitioning into the bilayers.
Journal of controlled release : official journal of the Controlled Release Society 1999;58(2):207-14.
1999: Merja Kirjavainen; Arto Urtti; R Valjakka-Koskela; Juha Kiesvaara; Jukka Mönkkönen
Liposome-skin interactions and their effects on the skin permeation of drugs.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 1999;7(4):279-86.
1999: Satu Akerman; B Svarfvar; Kyösti Kontturi; Johnny Näsman; Arto Urtti; Timo Petteri Paronen; Kristiina Järvinen
Influence of ionic strength on drug adsorption onto and release from a poly(acrylic acid) grafted poly(vinylidene fluoride) membrane.
International journal of pharmaceutics 1999;178(1):67-75.
1999: Marika Ruponen; Seppo Ylä-Herttuala; Arto Urtti
Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies.
Biochimica et biophysica acta 1999;1415(2):331-41.
1999: Mikko Turunen; Mikko O Hiltunen; Marika Ruponen; L Virkamäki; Francis Szoka, jr; Arto Urtti; Seppo Ylä-Herttuala
Efficient adventitial gene delivery to rabbit carotid artery with cationic polymer-plasmid complexes.
Gene therapy 1999;6(1):6-11.
1998: Kaisa Mari Hämäläinen; E Määttä; H Piirainen; A Väisänen; Veli-Pekka Ranta; Arto Urtti
Roles of acid/base nature and molecular weight in drug release from matrices of gelfoam and monoisopropyl ester of poly(vinyl methyl ether-maleic anhydride).
Journal of controlled release : official journal of the Controlled Release Society 1998;56(1-3):273-83.
1998: Hanna Kanerva; H Huuskonen; A Alhonen-Raatesalmi; T Nevalainen; Arto Urtti
Pharmacokinetics of deramciclane in dogs after single oral and intravenous dosing and multiple oral dosing.
Biopharmaceutics & drug disposition 1998;19(8):531-9.
1998: Hanna Kanerva; Imre Klebovich; Sándor Drabant; Arto Urtti; T Nevalainen
Different absorption profiles of deramciclane in man and in dog.
The Journal of pharmacy and pharmacology 1998;50(10):1087-93.
1998: P Saarinen-Savolainen; Tomi Järvinen; K Araki-Sasaki; H Watanabe; Arto Urtti
Evaluation of cytotoxicity of various ophthalmic drugs, eye drop excipients and cyclodextrins in an immortalized human corneal epithelial cell line.
Pharmaceutical research 1998;15(8):1275-80.
1998: Pekka Suhonen; Tomi Järvinen; S Koivisto; Arto Urtti
Different effects of pH on the permeation of pilocarpine and pilocarpine prodrugs across the isolated rabbit cornea.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 1998;6(3):169-76.
1998: Veli-Pekka Ranta; Kaisa Mari Hämäläinen; Seppo Auriola; Arto Urtti
Gradient high-performance liquid chromatographic analysis of enkephalin peptides, their metabolites, and enzyme inhibitors using combined ultraviolet and electrochemical detection II. Application to ocular permeability studies in vitro.
Journal of chromatography. B, Biomedical sciences and applications 1998;709(1):1-10.
1998: Satu Akerman; P Viinikka; B Svarfvar; Kristiina Järvinen; Kyösti Kontturi; Johnny Näsman; Arto Urtti; Timo Petteri Paronen
Transport of drugs across porous ion exchange membranes.
Journal of controlled release : official journal of the Controlled Release Society 1998;50(1-3):153-66.
1998: David W Pate; Kristiina Järvinen; Arto Urtti; V Mahadevan; Tomi Järvinen
Effect of the CB1 receptor antagonist, SR141716A, on cannabinoid-induced ocular hypotension in normotensive rabbits.
Life sciences 1998;63(24):2181-8.
1997: Elena Azhayeva; Alex Azhayev; Seppo Auriola; Unni Tengvall; Arto Urtti
Inhibitory properties of double-helix-forming circular oligonucleotides.
Nucleic acids research 1997;25(24):4954-61.
1997: David W Pate; Kristiina Järvinen; Arto Urtti; Pekka Jarho; V Mahadevan; Tomi Järvinen
Effects of topical alpha-substituted anandamides on intraocular pressure in normotensive rabbits.
Pharmaceutical research 1997;14(12):1738-43.
1997: Kaisa Mari Hämäläinen; K Kananen; Seppo Auriola; Kyösti Kontturi; Arto Urtti
Characterization of paracellular and aqueous penetration routes in cornea, conjunctiva, and sclera.
Investigative ophthalmology & visual science 1997;38(3):627-34.
1996: Merja Kirjavainen; Arto Urtti; Ilpo Jääskeläinen; T M Suhonen; Timo Petteri Paronen; R Valjakka-Koskela; Juha Kiesvaara; Jukka Mönkkönen
Interaction of liposomes with human skin in vitro--the influence of lipid composition and structure.
Biochimica et biophysica acta 1996;1304(3):179-89.
1996: Pekka Jarho; Kristiina Järvinen; Arto Urtti; Valentino J Stella; Tomi Järvinen
Modified beta-cyclodextrin (SBE7-beta-CyD) with viscous vehicle improves the ocular delivery and tolerability of pilocarpine prodrug in rabbits.
The Journal of pharmacy and pharmacology 1996;48(3):263-9.
1996: Ritva Ylitalo; Jukka Mönkkönen; Arto Urtti; Pauli Ylitalo
Accumulation of bisphosphonates in the aorta and some other tissues of healthy and atherosclerotic rabbits.
The Journal of laboratory and clinical medicine 1996;127(2):200-6.
1996: David W Pate; Kristiina Järvinen; Arto Urtti; Pekka Jarho; M Fich; V Mahadevan; Tomi Järvinen
Effects of topical anandamides on intraocular pressure in normotensive rabbits.
Life sciences 1996;58(21):1849-60.
1996: Pekka Jarho; Arto Urtti; Kristiina Järvinen; David W Pate; Tomi Järvinen
Hydroxypropyl-beta-cyclodextrin increases aqueous solubility and stability of anandamide.
Life sciences 1996;58(10):PL 181-5.
1995: Pekka Jarho; Arto Urtti; Tomi Järvinen
Hydroxypropyl-beta-cyclodextrin increases the aqueous solubility and stability of pilocarpine prodrugs.
Pharmaceutical research 1995;12(9):1371-5.
1995: David W Pate; Kristiina Järvinen; Arto Urtti; Pekka Jarho; Tomi Järvinen
Ophthalmic arachidonylethanolamide decreases intraocular pressure in normotensive rabbits.
Current eye research 1995;14(9):791-7.
1995: N Pennanen; S Lapinjoki; Arto Urtti; Jukka Mönkkönen
Effect of liposomal and free bisphosphonates on the IL-1 beta, IL-6 and TNF alpha secretion from RAW 264 cells in vitro.
Pharmaceutical research 1995;12(6):916-22.
1995: N Pennanen; S Lapinjoki; A Palander; Arto Urtti; Jukka Mönkkönen
Macrophage-like RAW 264 cell line and time-resolved fluoroimmunoassay (TRFIA) as tools in screening drug effects on cytokine secretion.
International journal of immunopharmacology 1995;17(6):475-80.
1995: Tomi Järvinen; M Poikolainen; P Suhonen; Jouko Vepsäläinen; S Alaranta; Arto Urtti
Comparison of enzymatic hydrolysis of pilocarpine prodrugs in human plasma, rabbit cornea, and butyrylcholinesterase solutions.
Journal of pharmaceutical sciences 1995;84(5):656-60.
1995: P Suhonen; Tomi Järvinen; K Lehmussaari; T Reunamäki; Arto Urtti
Ocular absorption and irritation of pilocarpine prodrug is modified with buffer, polymer, and cyclodextrin in the eyedrop.
Pharmaceutical research 1995;12(4):529-33.
1995: Tomi Järvinen; Kristiina Järvinen; Arto Urtti; D Thompson; Valentino J Stella
Sulfobutyl ether beta-cyclodextrin (SBE-beta-CD) in eyedrops improves the tolerability of a topically applied pilocarpine prodrug in rabbits.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 1995;11(2):95-106.
1994: K Lappalainen; Arto Urtti; E Söderling; Ilpo Jääskeläinen; Kari Syrjänen; Stina Syrjänen
Cationic liposomes improve stability and intracellular delivery of antisense oligonucleotides into CaSki cells.
Biochimica et biophysica acta 1994;1196(2):201-8.
1994: Ilpo Jääskeläinen; Jukka Mönkkönen; Arto Urtti
Oligonucleotide-cationic liposome interactions. A physicochemical study.
Biochimica et biophysica acta 1994;1195(1):115-23.
1994: Arto Urtti; H Rouhiainen; T Kaila; V Saano
Controlled ocular timolol delivery: systemic absorption and intraocular pressure effects in humans.
Pharmaceutical research 1994;11(9):1278-82.
1994: K Lappalainen; Ilpo Jääskeläinen; Kari Syrjänen; Arto Urtti; Stina Syrjänen
Comparison of cell proliferation and toxicity assays using two cationic liposomes.
Pharmaceutical research 1994;11(8):1127-31.
1994: Ilpo Jääskeläinen; Arto Urtti
Liquid chromatography determination of liposome components using a light-scattering evaporative detector.
Journal of pharmaceutical and biomedical analysis 1994;12(8):977-82.
1994: T M Turunen; Arto Urtti; Timo Petteri Paronen; Kenneth L Audus; J H Rytting
Effect of some penetration enhancers on epithelial membrane lipid domains: evidence from fluorescence spectroscopy studies.
Pharmaceutical research 1994;11(2):288-94.
1994: K Lappalainen; Arto Urtti; Ilpo Jääskeläinen; Kari Syrjänen; Stina Syrjänen
Cationic liposomes mediated delivery of antisense oligonucleotides targeted to HPV 16 E7 mRNA in CaSki cells.
Antiviral research 1994;23(2):119-30.
1994: Arto Urtti
Delivery of antiglaucoma drugs: ocular vs systemic absorption.
Journal of ocular pharmacology 1994;10(1):349-57.
1994: Jukka Mönkkönen; N Pennanen; S Lapinjoki; Arto Urtti
Clodronate (dichloromethylene bisphosphonate) inhibits LPS-stimulated IL-6 and TNF production by RAW 264 cells.
Life sciences 1994;54(14):PL229-34.
1994: Jukka Mönkkönen; M Taskinen; Seppo Auriola; Arto Urtti
Growth inhibition of macrophage-like and other cell types by liposome-encapsulated, calcium-bound, and free bisphosphonates in vitro.
Journal of drug targeting 1994;2(4):299-308.
1993: Seppo Auriola; K M Rönkkö; Arto Urtti
Determination of polyethylene glycols by high-performance liquid chromatography-thermospray mass spectrometry.
Journal of pharmaceutical and biomedical analysis 1993;11(10):1027-32.
1993: E MacDonald; J Vartiainen; K Jäsberg; L Vuorilehto; J S Salonen; Arto Urtti
Systemic absorption and systemic effects of ocularly administered dexmedetomidine in rabbits.
Current eye research 1993;12(5):451-60.
1993: Arto Urtti; L Salminen
Minimizing systemic absorption of topically administered ophthalmic drugs.
Survey of ophthalmology 1993;37(6):435-56.
1993: Kyösti Kontturi; Lasse Murtomäki; Jouni Hirvonen; Timo Petteri Paronen; Arto Urtti
Electrochemical characterization of human skin by impedance spectroscopy: the effect of penetration enhancers.
Pharmaceutical research 1993;10(3):381-5.
1993: M Fabrizio Saettone; Patrizia Chetoni; L Cappanera; Ubaldo Conte; U Finne; Kristiina Järvinen; J Salivirta; Arto Urtti
Intraocular pressure reduction and systemic absorption of timolol after administration of one side-coated inserts in rabbits.
Journal of ocular pharmacology 1993;9(1):1-12.
1992: Kristiina Järvinen; Arto Urtti
Cardiac effects of different eyedrop preparations of timolol in rabbits.
Current eye research 1992;11(5):469-73.
1992: J Vartiainen; E MacDonald; Arto Urtti; H Rouhiainen; Raine Virtanen
Dexmedetomidine-induced ocular hypotension in rabbits with normal or elevated intraocular pressures.
Investigative ophthalmology & visual science 1992;33(6):2019-23.
1992: Tomi Järvinen; P Suhonen; Seppo Auriola; Jouko Vepsäläinen; Arto Urtti; P Peura
Synthesis and analysis of O,O'-dicarboxylate (dibenzyl) bispilocarpates as possible prodrugs of pilocarpine.
Journal of pharmaceutical and biomedical analysis 1992;10(2-3):153-61.
1992: Kristiina Järvinen; Arto Urtti
Duration and long-term efficacy of phenylephrine-induced reduction in the systemic absorption of ophthalmic timolol in rabbits.
Journal of ocular pharmacology 1992;8(2):91-8.
1991: P Suhonen; Tomi Järvinen; P Rytkönen; P Peura; Arto Urtti
Improved corneal pilocarpine permeability with O,O'-(1,4-xylylene) bispilocarpic acid ester double prodrugs.
Pharmaceutical research 1991;8(12):1539-42.
1991: U Finne; K Rönkkö; Arto Urtti
Timolol release from matrices of monoesters of poly(vinyl methyl ether-maleic anhydride): effects of polymer molecular weight and a basic additive.
Journal of pharmaceutical sciences 1991;80(7):670-3.
1991: Jouni Hirvonen; J H Rytting; Timo Petteri Paronen; Arto Urtti
Dodecyl N,N-dimethylamino acetate and azone enhance drug penetration across human, snake, and rabbit skin.
Pharmaceutical research 1991;8(7):933-7.
1991: Tomi Järvinen; P Suhonen; H Naumanen; Arto Urtti; P Peura
Determination of physicochemical properties, stability in aqueous solutions and serum hydrolysis of pilocarpic acid diesters.
Journal of pharmaceutical and biomedical analysis 1991;9(9):737-45.
1991: Tomi Järvinen; Seppo Auriola; P Peura; P Suhonen; Arto Urtti; Jouko Vepsäläinen
Synthesis and identification of pilocarpic acid diesters, prodrugs of pilocarpine.
Journal of pharmaceutical and biomedical analysis 1991;9(6):457-64.
1990: K Kyyrönen; Arto Urtti
Improved ocular: systemic absorption ratio of timolol by viscous vehicle and phenylephrine.
Investigative ophthalmology & visual science 1990;31(9):1827-33.
1990: K Kyyrönen; Arto Urtti
Effects of epinephrine pretreatment and solution pH on ocular and systemic absorption of ocularly applied timolol in rabbits.
Journal of pharmaceutical sciences 1990;79(8):688-91.
1989: Jukka Mönkkönen; Arto Urtti; Timo Petteri Paronen; H A Elo; Pauli Ylitalo
The uptake of clodronate (dichloromethylene bisphosphonate) by macrophages in vivo and in vitro.
Drug metabolism and disposition: the biological fate of chemicals 1989;17(6):690-3.
1989: Arto Urtti; K Kyyrönen
Ophthalmic epinephrine, phenylephrine, and pilocarpine affect the systemic absorption of ocularly applied timolol.
Journal of ocular pharmacology 1989;5(2):127-32.
1988: Arto Urtti; T Sendo; J D Pipkin; G Rork; A J Repta
Application site dependent ocular absorption of timolol.
Journal of ocular pharmacology 1988;4(4):335-43.
1987: Risto Huupponen; T Kaila; Lotta Salminen; Arto Urtti
The pharmacokinetics of ocularly applied timolol in rabbits.
Acta ophthalmologica 1987;65(1):63-6.
1985: Arto Urtti; L Salminen
Concentration-dependent precorneal loss of pilocarpine in rabbit eyes.
Acta ophthalmologica 1985;63(5):502-6.
1985: Arto Urtti; L M Salminen
Pilocarpine and acetylcholine synthesis.
Archives of ophthalmology 1985;103(4):477.
1985: Arto Urtti; L Salminen
A comparison between iris-ciliary body concentration and receptor affinity of timolol.
Acta ophthalmologica 1985;63(1):16-8.
1984: Arto Urtti; L Salminen; L Periviita
Ocular distribution of topically applied adrenaline in albino and pigmented rabbits.
Acta ophthalmologica 1984;62(5):753-62.
1984: L Salminen; Arto Urtti
Disposition of ophthalmic timolol in treated and untreated rabbit eyes. A multiple and single dose study.
Experimental eye research 1984;38(2):203-6.
1983: L Salminen; Arto Urtti; H Kujari; M Juslin
Prolonged pulse-entry of pilocarpine with a soluble drug insert.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1983;221(2):96-9.
1982: V Saano; Arto Urtti
Tofizopam modulates the affinity of benzodiazepine receptors in the rat brain.
Pharmacology, biochemistry, and behavior 1982;17(2):367-9.
1981: V Saano; Arto Urtti; M M Airaksinen
Increase in 3H-flunitrazepam binding in vitro and in vivo to rat brain benzodiazepine receptors by tofizopam, a 3,4-benzo-diazepine.
Pharmacological research communications 1981;13(1):75-85.