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Alun Davies

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Anatomy

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Co-Publications
Name
22
Wyatt, Sean
20
Buchman, Vladimir
14
Ninkina, Natalia
13
Middleton, G
7
Adu, J
5
Piñón, LG
5
Horton, Antony
4
Doxakis, Epaminondas
4
Maina, Flavio
4
Doxakis, E
4
Forgie, Alison
4
Klein, Rudiger
3
Gutierrez, Humberto
3
Hanger, Diane
3
Anderton, Brian

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Publications

TOP 3
Doxakis Epaminondas; Howard Laura; Rohrer Hermann; Davies Alun M
HAND transcription factors are required for neonatal sympathetic neuron survival.
Gutierrez Humberto; O'Keeffe Gerard W; Gavaldà Núria; Gallagher Denis; Davies Alun M
Nuclear factor kappa B signaling either stimulates or inhibits neurite growth depending on the phosphorylation status of p65/RelA.
Davies Alun M
Neurotrophins giveth and they taketh away.

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All Publications

2008: Doxakis Epaminondas; Howard Laura; Rohrer Hermann; Davies Alun M
HAND transcription factors are required for neonatal sympathetic neuron survival.
EMBO reports 2008;9(10):1041-7.
2008: Gutierrez Humberto; O'Keeffe Gerard W; Gavaldà Núria; Gallagher Denis; Davies Alun M
Nuclear factor kappa B signaling either stimulates or inhibits neurite growth depending on the phosphorylation status of p65/RelA.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(33):8246-56.
2008: Davies Alun M
Neurotrophins giveth and they taketh away.
Nature neuroscience 2008;11(6):627-8.
2008: Bishop Tammie; Gallagher Denis; Pascual Alberto; Lygate Craig A; de Bono Joseph P; Nicholls Lynn G; Ortega-Saenz Patricia; Oster Henrik; Wijeyekoon Bhathiya; Sutherland Andrew I; Grosfeld Alexandra; Aragones Julian; Schneider Martin; van Geyte Katie; Teixeira Dania; Diez-Juan Antonio; Lopez-Barneo Jose; Channon Keith M; Maxwell Patrick H; Pugh Christopher W; Davies Alun M; Carmeliet Peter; Ratcliffe Peter J
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice.
Molecular and cellular biology 2008;28(10):3386-400.
2008: Vizard Thomas N; O'Keeffe Gerard W; Gutierrez Humberto; Kos Claudine H; Riccardi Daniela; Davies Alun M
Regulation of axonal and dendritic growth by the extracellular calcium-sensing receptor.
Nature neuroscience 2008;11(3):285-91.
2008: O'Keeffe Gerard W; Gutierrez Humberto; Pandolfi Pier Paolo; Riccardi Carlo; Davies Alun M
NGF-promoted axon growth and target innervation requires GITRL-GITR signaling.
Nature neuroscience 2008;11(2):135-42.
2008: Andres Rosa; Herraez-Baranda Luis A; Thompson Jane; Wyatt Sean; Davies Alun M
Regulation of sympathetic neuron differentiation by endogenous nerve growth factor and neurotrophin-3.
Neuroscience letters 2008;431(3):241-6.
2007: Gallagher Denis; Gutierrez Humberto; Gavalda Nuria; O'Keeffe Gerard; Hay Ron; Davies Alun M
Nuclear factor-kappaB activation via tyrosine phosphorylation of inhibitor kappaB-alpha is crucial for ciliary neurotrophic factor-promoted neurite growth from developing neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(36):9664-9.
2007: Gutierrez Humberto; Davies Alun M
A fast and accurate procedure for deriving the Sholl profile in quantitative studies of neuronal morphology.
Journal of neuroscience methods 2007;163(1):24-30.
2006: Hefti Franz F; Rosenthal Arnon; Walicke Patricia A; Wyatt Sean; Vergara German; Shelton David L; Davies Alun M
Novel class of pain drugs based on antagonism of NGF.
Trends in pharmacological sciences 2006;27(2):85-91.
2005: Pante Guido; Thompson Jane; Lamballe Fabienne; Iwata Tomoko; Ferby Ingvar; Barr Francis A; Davies Alun M; Maina Flavio; Klein Rüdiger
Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/Met-induced cell migration and neurite growth.
The Journal of cell biology 2005;171(2):337-48.
2005: Doxakis Epaminondas; Davies Alun M
Retinoic acid negatively regulates GDNF and neurturin receptor expression and responsiveness in embryonic chicken sympathetic neurons.
Molecular and cellular neurosciences 2005;29(4):617-27.
2004: Thompson Jane; Dolcet Xavier; Hilton Mark; Tolcos Mary; Davies Alun M
HGF promotes survival and growth of maturing sympathetic neurons by PI-3 kinase- and MAP kinase-dependent mechanisms.
Molecular and cellular neurosciences 2004;27(4):441-52.
2004: Sole Carme; Dolcet Xavier; Segura Miguel F; Gutierrez Humberto; Diaz-Meco Maria-Teresa; Gozzelino Raffaella; Sanchis Daniel; Bayascas Jose R; Gallego Carme; Moscat Jorge; Davies Alun M; Comella Joan X
The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-kapp B signaling.
The Journal of cell biology 2004;167(3):479-92.
2004: Doxakis Epaminondas; Huang Eric J; Davies Alun M
Homeodomain-interacting protein kinase-2 regulates apoptosis in developing sensory and sympathetic neurons.
Current biology : CB 2004;14(19):1761-5.
2004: Saha Anirban R; Hill Josephine; Utton Michelle A; Asuni Ayodeji A; Ackerley Steven; Grierson Andrew J; Miller Christopher C; Davies Alun M; Buchman Vladimir L; Anderton Brian H; Hanger Diane P
Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons.
Journal of cell science 2004;117(Pt 7):1017-24.
2003: Ninkina Natalia; Papachroni Katerina; Robertson Darren C; Schmidt Oliver; Delaney Liz; O'Neill Francis; Court Felipe; Rosenthal Arnon; Fleetwood-Walker Susan M; Davies Alun M; Buchman Vladimir L
Neurons expressing the highest levels of gamma-synuclein are unaffected by targeted inactivation of the gene.
Molecular and cellular biology 2003;23(22):8233-45.
2003: Davies Alun M
Regulation of neuronal survival and death by extracellular signals during development.
The EMBO journal 2003;22(11):2537-45.
2003: Forgie Alison; Wyatt Sean; Correll Pamela H; Davies Alun M
Macrophage stimulating protein is a target-derived neurotrophic factor for developing sensory and sympathetic neurons.
Development (Cambridge, England) 2003;130(5):995-1002.
2002: Schmidt Oliver; Doxakis Epaminondas; Davies Alun M
Macrophage-stimulating protein is a neurotrophic factor for embryonic chicken hypoglossal motoneurons.
The European journal of neuroscience 2002;15(1):101-8.
2001: Middleton G; Davies A M
Populations of NGF-dependent neurones differ in their requirement for BAX to undergo apoptosis in the absence of NGF/TrkA signalling in vivo.
Development (Cambridge, England) 2001;128(23):4715-28.
2001: Barker V; Middleton G; Davey F; Davies A M
TNFalpha contributes to the death of NGF-dependent neurons during development.
Nature neuroscience 2001;4(12):1194-8.
2001: Andres R; Forgie A; Wyatt S; Chen Q; de Sauvage F J; Davies A M
Multiple effects of artemin on sympathetic neurone generation, survival and growth.
Development (Cambridge, England) 2001;128(19):3685-95.
2001: Alonzi T; Middleton G; Wyatt S; Buchman V; Betz U A; Müller W; Musiani P; Poli V; Davies A M
Role of STAT3 and PI 3-kinase/Akt in mediating the survival actions of cytokines on sensory neurons.
Molecular and cellular neurosciences 2001;18(3):270-82.
2001: Orike N; Middleton G; Borthwick E; Buchman V; Cowen T; Davies A M
Role of PI 3-kinase, Akt and Bcl-2-related proteins in sustaining the survival of neurotrophic factor-independent adult sympathetic neurons.
The Journal of cell biology 2001;154(5):995-1005.
2001: Maina F; Panté G; Helmbacher F; Andres R; Porthin A; Davies A M; Ponzetto C; Klein R
Coupling Met to specific pathways results in distinct developmental outcomes.
Molecular cell 2001;7(6):1293-306.
2001: Middleton G; Wyatt S; Ninkina N; Davies A M
Reciprocal developmental changes in the roles of Bcl-w and Bcl-x(L) in regulating sensory neuron survival.
Development (Cambridge, England) 2001;128(3):447-57.
2000: Tiunova A A; Anokhin K V; Saha A R; Schmidt O; Hanger D P; Anderton B H; Davies A M; Ninkina N N; Buchman V L
Chicken synucleins: cloning and expression in the developing embryo.
Mechanisms of development 2000;99(1-2):195-8.
2000: Saha A R; Ninkina N N; Hanger D P; Anderton B H; Davies A M; Buchman V L
Induction of neuronal death by alpha-synuclein.
The European journal of neuroscience 2000;12(8):3073-7.
2000: Gout I; Middleton G; Adu J; Ninkina N N; Drobot L B; Filonenko V; Matsuka G; Davies A M; Waterfield M; Buchman V L
Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein.
The EMBO journal 2000;19(15):4015-25.
2000: Davies A M
Neurotrophins: more to NGF than just survival.
Current biology : CB 2000;10(10):R374-6.
2000: Doxakis E; Wyatt S; Davies A M
Depolarisation causes reciprocal changes in GFR(alpha)-1 and GFR(alpha)-2 receptor expression and shifts responsiveness to GDNF and neurturin in developing neurons.
Development (Cambridge, England) 2000;127(7):1477-87.
2000: Middleton G; Cox S W; Korsmeyer S; Davies A M
Differences in bcl-2- and bax-independent function in regulating apoptosis in sensory neuron populations.
The European journal of neuroscience 2000;12(3):819-27.
2000: Davies A M
Neurotrophins: neurotrophic modulation of neurite growth.
Current biology : CB 2000;10(5):R198-200.
2000: Forgie A; Kuehnel F; Wyatt S; Davies A M
In vivo survival requirement of a subset of nodose ganglion neurons for nerve growth factor.
The European journal of neuroscience 2000;12(2):670-6.
2000: Huber K; Kuehnel F; Wyatt S; Davies A M
TrkB expression and early sensory neuron survival are independent of endogenous BDNF.
Journal of neuroscience research 2000;59(3):372-8.
2000: Davey F; Hilton M; Davies A M
Cooperation between HGF and CNTF in promoting the survival and growth of sensory and parasympathetic neurons.
Molecular and cellular neurosciences 2000;15(1):79-87.
2000: Middleton G; Hamanoue M; Enokido Y; Wyatt S; Pennica D; Jaffray E; Hay R T; Davies A M
Cytokine-induced nuclear factor kappa B activation promotes the survival of developing neurons.
The Journal of cell biology 2000;148(2):325-32.
1999: Enokido Y; Wyatt S; Davies A M
Developmental changes in the response of trigeminal neurons to neurotrophins: influence of birthdate and the ganglion environment.
Development (Cambridge, England) 1999;126(19):4365-73.
1999: Wyatt S; Middleton G; Doxakis E; Davies A M
Selective regulation of trkC expression by NT3 in the developing peripheral nervous system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(15):6559-70.
1999: Hamanoue M; Middleton G; Wyatt S; Jaffray E; Hay R T; Davies A M
p75-mediated NF-kappaB activation enhances the survival response of developing sensory neurons to nerve growth factor.
Molecular and cellular neurosciences 1999;14(1):28-40.
1999: Forgie A; Doxakis E; Buj-Bello A; Wyatt S; Davies A M
Differences and developmental changes in the responsiveness of PNS neurons to GDNF and neurturin.
Molecular and cellular neurosciences 1999;13(6):430-40.
1999: Alimova-Kost M V; Ninkina N N; Imreh S; Gnuchev N V; Adu J; Davies A M; Buchman V L
Genomic structure and chromosomal localization of the mouse persyn gene.
Genomics 1999;56(2):224-7.
1999: Ninkina N N; Privalova E M; Pinõn L G; Davies A M; Buchman V L
Developmentally regulated expression of persyn, a member of the synuclein family, in skin.
Experimental cell research 1999;246(2):308-11.
1999: Wyatt S; Andres R; Rohrer H; Davies A M
Regulation of neurotrophin receptor expression by retinoic acid in mouse sympathetic neuroblasts.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(3):1062-71.
1998: Buchman V L; Hunter H J; Pinõn L G; Thompson J; Privalova E M; Ninkina N N; Davies A M
Persyn, a member of the synuclein family, has a distinct pattern of expression in the developing nervous system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(22):9335-41.
1998: Enokido Y; de Sauvage F; Hongo J A; Ninkina N; Rosenthal A; Buchman V L; Davies A M
GFR alpha-4 and the tyrosine kinase Ret form a functional receptor complex for persephin.
Current biology : CB 1998;8(18):1019-22.
1998: Ninkina N N; Alimova-Kost M V; Paterson J W; Delaney L; Cohen B B; Imreh S; Gnuchev N V; Davies A M; Buchman V L
Organization, expression and polymorphism of the human persyn gene.
Human molecular genetics 1998;7(9):1417-24.
1998: Minichiello L; Casagranda F; Tatche R S; Stucky C L; Postigo A; Lewin G R; Davies A M; Klein R
Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses.
Neuron 1998;21(2):335-45.
1998: Davey F; Davies A M
TrkB signalling inhibits p75-mediated apoptosis induced by nerve growth factor in embryonic proprioceptive neurons.
Current biology : CB 1998;8(16):915-8.
1998: Buchman V L; Adu J; Pinõn L G; Ninkina N N; Davies A M
Persyn, a member of the synuclein family, influences neurofilament network integrity.
Nature neuroscience 1998;1(2):101-3.
1998: Thompson J; Doxakis E; Piñón L G; Strachan P; Buj-Bello A; Wyatt S; Buchman V L; Davies A M
GFRalpha-4, a new GDNF family receptor.
Molecular and cellular neurosciences 1998;11(3):117-26.
1998: Maina F; Hilton M C; Andres R; Wyatt S; Klein R; Davies A M
Multiple roles for hepatocyte growth factor in sympathetic neuron development.
Neuron 1998;20(5):835-46.
1998: Middleton G; Piñón L G; Wyatt S; Davies A M
Bcl-2 accelerates the maturation of early sensory neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(9):3344-50.
1998: Horton A R; Barlett P F; Pennica D; Davies A M
Cytokines promote the survival of mouse cranial sensory neurones at different developmental stages.
The European journal of neuroscience 1998;10(2):673-9.
1998: Davies A M
Neuronal survival: early dependence on Schwann cells.
Current biology : CB 1998;8(1):R15-8.
1998: Davies A M
Developmental changes in the neurotrophic factor survival requirements of peripheral nervous system neurons.
Progress in brain research 1998;117():47-56.
1997: Maina F; Hilton M C; Ponzetto C; Davies A M; Klein R
Met receptor signaling is required for sensory nerve development and HGF promotes axonal growth and survival of sensory neurons.
Genes & development 1997;11(24):3341-50.
1997: Davies A M
Studies of neurotrophin biology in the developing trigeminal system.
Journal of anatomy 1997;191 ( Pt 4)():483-91.
1997: Piñón L G; Middleton G; Davies A M
Bcl-2 is required for cranial sensory neuron survival at defined stages of embryonic development.
Development (Cambridge, England) 1997;124(20):4173-8.
1997: Hilton M; Middleton G; Davies A M
Bcl-2 influences axonal growth rate in embryonic sensory neurons.
Current biology : CB 1997;7(10):798-800.
1997: Wyatt S; Piñon L G; Ernfors P; Davies A M
Sympathetic neuron survival and TrkA expression in NT3-deficient mouse embryos.
The EMBO journal 1997;16(11):3115-23.
1997: Buj-Bello A; Adu J; Piñón L G; Horton A; Thompson J; Rosenthal A; Chinchetru M; Buchman V L; Davies A M
Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase.
Nature 1997;387(6634):721-4.
1997: Ninkina N; Grashchuck M; Buchman V L; Davies A M
TrkB variants with deletions in the leucine-rich motifs of the extracellular domain.
The Journal of biological chemistry 1997;272(20):13019-25.
1997: Davies A M
Neurotrophin switching: where does it stand?
Current opinion in neurobiology 1997;7(1):110-8.
1997: Davies A M
Neurotrophins: the yin and yang of nerve growth factor.
Current biology : CB 1997;7(1):R38-40.
1997: Horton A; Laramee G; Wyatt S; Shih A; Winslow J; Davies A M
NGF binding to p75 enhances the sensitivity of sensory and sympathetic neurons to NGF at different stages of development.
Molecular and cellular neurosciences 1997;10(3-4):162-72.
1996: Ninkina N; Adu J; Fischer A; Piñón L G; Buchman V L; Davies A M
Expression and function of TrkB variants in developing sensory neurons.
The EMBO journal 1996;15(23):6385-93.
1996: Robinson M; Adu J; Davies A M
Timing and regulation of trkB and BDNF mRNA expression in placode-derived sensory neurons and their targets.
The European journal of neuroscience 1996;8(11):2399-406.
1996: Piñon L G; Minichiello L; Klein R; Davies A M
Timing of neuronal death in trkA, trkB and trkC mutant embryos reveals developmental changes in sensory neuron dependence on Trk signalling.
Development (Cambridge, England) 1996;122(10):3255-61.
1996: Davies A M
Paracrine and autocrine actions of neurotrophic factors.
Neurochemical research 1996;21(7):749-53.
1996: Baka I D; Ninkina N N; Pinon L G; Adu J; Davies A M; Georgiev G P; Buchman V L
Intracellular compartmentalization of two differentially spliced s-rex/NSP mRNAs in neurons.
Molecular and cellular neurosciences 1996;7(4):289-303.
1996: Davies A M
The neurotrophic hypothesis: where does it stand?
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1996;351(1338):389-94.
1996: Robinson M; Buj-Bello A; Davies A M
Paracrine interactions of BDNF involving NGF-dependent embryonic sensory neurons.
Molecular and cellular neurosciences 1996;7(2):143-51.
1996: Middleton G; Nunez G; Davies A M
Bax promotes neuronal survival and antagonises the survival effects of neurotrophic factors.
Development (Cambridge, England) 1996;122(2):695-701.
1996: Horton A R; Davies A M; Buj-Bello A; Bartlett P; Murphy M
Leukemia inhibitory factor and ciliary neurotrophic factor in sensory neuron development.
Perspectives on developmental neurobiology 1996;4(1):35-8.
1995: Pinon L G; Robinson M; Davies A M
High specificity of neurotrophins in the embryonic chicken trigeminal system.
The European journal of neuroscience 1995;7(12):2397-402.
1995: Buj-Bello A; Buchman V L; Horton A; Rosenthal A; Davies A M
GDNF is an age-specific survival factor for sensory and autonomic neurons.
Neuron 1995;15(4):821-8.
1995: Paul G; Davies A M
Trigeminal sensory neurons require extrinsic signals to switch neurotrophin dependence during the early stages of target field innervation.
Developmental biology 1995;171(2):590-605.
1995: Davies A M; Wyatt S; Nishimura M; Phillips H
NGF receptor expression in sensory neurons develops normally in embryos lacking NGF.
Developmental biology 1995;171(2):434-8.
1995: Wyatt S; Davies A M
Regulation of nerve growth factor receptor gene expression in sympathetic neurons during development.
The Journal of cell biology 1995;130(6):1435-46.
1995: Davies A M; Minichiello L; Klein R
Developmental changes in NT3 signalling via TrkA and TrkB in embryonic neurons.
The EMBO journal 1995;14(18):4482-9.
1995: Davies A M; Wright E M
Neurotrophic factors. Neurotrophin autocrine loops.
Current biology : CB 1995;5(7):723-6.
1994: Davies A M
Neural development. Chemoattractants for navigating axons.
Current biology : CB 1994;4(12):1142-5.
1994: Buchman V L; Sporn M; Davies A M
Role of transforming growth factor-beta isoforms in regulating the expression of nerve growth factor and neurotrophin-3 mRNA levels in embryonic cutaneous cells at different stages of development.
Development (Cambridge, England) 1994;120(6):1621-9.
1994: Buj-Bello A; Pinon L G; Davies A M
The survival of NGF-dependent but not BDNF-dependent cranial sensory neurons is promoted by several different neurotrophins early in their development.
Development (Cambridge, England) 1994;120(6):1573-80.
1994: Davies A M
Neurotrophic factors. Switching neurotrophin dependence.
Current biology : CB 1994;4(3):273-6.
1994: Davies A M
The role of neurotrophins during successive stages of sensory neuron development.
Progress in growth factor research 1994;5(3):263-89.
1993: Davies A M
Promoting motor neuron survival.
Current biology : CB 1993;3(12):879-81.
1993: Wyatt S; Davies A M
Regulation of expression of mRNAs encoding the nerve growth factor receptors p75 and trkA in developing sensory neurons.
Development (Cambridge, England) 1993;119(3):635-48.
1993: Davies A M; Lee K F; Jaenisch R
p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins.
Neuron 1993;11(4):565-74.

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