Auke Bult

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Stroink Thom; Ortiz Mireya Castillo; Bult Auke; Lingeman Henk; de Jong Gerhardus J; Underberg Willy J M
On-line multidimensional liquid chromatography and capillary electrophoresis systems for peptides and proteins.
Bouma M; Nuijen B; Harms R; Rice J R; Nowotnik D P; Stewart D R; Jansen B A J; van Zutphen S; Reedijk J; van Steenbergen M J; Talsma H; Bult A; Beijnen J H
Pharmaceutical development of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum anticancer agent AP 5280.
Bouma Marjan; Nuijen Bastiaan; Stewart Donald R; Shannon Kevin F; St John John V; Rice John R; Harms Remko; Jansen Bart A J; van Zutphen Steven; Reedijk Jan; Bult Auke; Beijnen Jos H
Pharmaceutical quality control of the investigational polymer-conjugated platinum anticancer agent AP 5280.

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2005: Stroink Thom; Ortiz Mireya Castillo; Bult Auke; Lingeman Henk; de Jong Gerhardus J; Underberg Willy J M
On-line multidimensional liquid chromatography and capillary electrophoresis systems for peptides and proteins.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;817(1):49-66.
2003: Bouma M; Nuijen B; Harms R; Rice J R; Nowotnik D P; Stewart D R; Jansen B A J; van Zutphen S; Reedijk J; van Steenbergen M J; Talsma H; Bult A; Beijnen J H
Pharmaceutical development of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum anticancer agent AP 5280.
Drug development and industrial pharmacy 2003;29(9):981-95.
2003: Bouma Marjan; Nuijen Bastiaan; Stewart Donald R; Shannon Kevin F; St John John V; Rice John R; Harms Remko; Jansen Bart A J; van Zutphen Steven; Reedijk Jan; Bult Auke; Beijnen Jos H
Pharmaceutical quality control of the investigational polymer-conjugated platinum anticancer agent AP 5280.
PDA journal of pharmaceutical science and technology / PDA 2003;57(3):198-207.
2003: Stroink Thom; Schravendijk Pim; Wiese Gerard; Teeuwsen Jan; Lingeman Henk; Waterval Joop C M; Bult Auke; de Jong Gerhardus J; Underberg Willy J M
On-line coupling of size-exclusion chromatography and capillary zone electrophoresis via a reversed-phase C18 trapping column for the determination of peptides in biological samples.
Electrophoresis 2003;24(6):1126-34.
2003: Stroink Thom; Wiese Gerard; Teeuwsen Jan; Lingeman Henk; Waterval Joop C M; Bult Auke; de Jong Gerhardus J; Underberg Willy J M
On-line coupling of size exclusion and capillary zone electrophoresis via a reversed-phase C18 trapping column for the analysis of structurally related enkephalins in cerebrospinal fluid.
Electrophoresis 2003;24(5):897-903.
2003: Bouma Marjan; Nuijen Bastiaan; Jansen Martine T; Sava Gianni; Picotti Fabrizio; Flaibani Antonella; Bult Auke; Beijnen Jos H
Development of a LC method for pharmaceutical quality control of the antimetastatic ruthenium complex NAMI-A.
Journal of pharmaceutical and biomedical analysis 2003;31(2):215-28.
2002: Bouma M; Nuijen B; Sava G; Perbellini A; Flaibani A; van Steenbergen M J; Talsma H; Kettenes-van den Bosch J J; Bult A; Beijnen J H
Pharmaceutical development of a parenteral lyophilized formulation of the antimetastatic ruthenium complex NAMI-A.
International journal of pharmaceutics 2002;248(1-2):247-59.
2002: Bouma Marjan; Nuijen Bastiaan; Jansen Martine T; Sava Gianni; Flaibani Antonella; Bult Auke; Beijnen Jos H
A kinetic study of the chemical stability of the antimetastatic ruthenium complex NAMI-A.
International journal of pharmaceutics 2002;248(1-2):239-46.
2002: Stroink Thom; Wiese Gerard; Teeuwsen Jan; Lingeman Henk; Waterval Joop C M; Bult Auke; de Jong Gerhardus J; Underberg Willy J M
On-line coupling of SEC and RP-LC for the determination of structurally related enkephalins in cerebrospinal fluid.
Journal of pharmaceutical and biomedical analysis 2002;30(4):1393-401.
2002: Bouma Marjan; Nuijen Bastiaan; Jansen Martine T; Sava Gianni; Bult Auke; Beijnen Jos H
Photostability profiles of the experimental antimetastatic ruthenium complex NAMI-A.
Journal of pharmaceutical and biomedical analysis 2002;30(4):1287-96.
2002: Bouma M; Nuijen B; Stewart D R; Rice J R; Jansen B A J; Reedijk J; Bult A; Beijnen J H
Stability and compatibility of the investigational polymer-conjugated platinum anticancer agent AP 5280 in infusion systems and its hemolytic potential.
Anti-cancer drugs 2002;13(9):915-24.
2001: Nuijen B; Bouma M; Talsma H; Manada C; Jimeno J M; Lopez-Lazaro L; Bult A; Beijnen J H
Development of a lyophilized parenteral pharmaceutical formulation of the investigational polypeptide marine anticancer agent kahalalide F.
Drug development and industrial pharmacy 2001;27(8):767-80.
2001: Waterval J C; Hommels G; Bestebreurtje P; Versluis C; Heck A J; Bult A; Lingeman H; Underberg W J
Capillary electrophoretic bioanalysis of therapeutically active peptides with UV and mass spectrometric detection after on-capillary preconcentration.
Electrophoresis 2001;22(13):2709-16.
2001: Waterval J C; Bestebreurtje P; Lingeman H; Versluis C; Heck A J; Bult A; Underberg W J
Robust and cost-effective capillary electrophoresis-mass spectrometry interfaces suitable for combination with on-line analyte preconcentration.
Electrophoresis 2001;22(13):2701-8.
2001: Stroink T; Paarlberg E; Waterval J C; Bult A; Underberg W J
On-line sample preconcentration in capillary electrophoresis, focused on the determination of proteins and peptides.
Electrophoresis 2001;22(12):2375-83.
2001: Nuijen B; Bouma M; Manada C; Jimeno J M; Bult A; Beijnen J H
In vitro hemolysis and buffer capacity studies with the novel marine anticancer agent kahalalide F and its reconstitution vehicle cremophor EL/ethanol.
PDA journal of pharmaceutical science and technology / PDA 2001;55(4):223-9.
2001: Waterval J C; Bloks J C; Sparidans R W; Beijnen J H; Rodriguez-Campos I M; Bult A; Lingeman H; Underberg W J
Degradation kinetics of aplidine, a new marine antitumoural cyclic peptide, in aqueous solution.
Journal of chromatography. B, Biomedical sciences and applications 2001;754(1):161-8.
2001: Nuijen B; Bouma M; Manada C; Jimeno J M; Lazaro L L; Bult A; Beijnen J H
Compatibility and stability of the investigational polypeptide marine anticancer agent kahalalide F in infusion devices.
Investigational new drugs 2001;19(4):273-81.
2000: Waterval J C; Lingeman H; Bult A; Underberg W J
Derivatization trends in capillary electrophoresis.
Electrophoresis 2000;21(18):4029-45.
2000: Nuijen B; Bouma M; Manada C; Jimeno J M; Schellens J H; Bult A; Beijnen J H
Pharmaceutical development of anticancer agents derived from marine sources.
Anti-cancer drugs 2000;11(10):793-811.
2000: Waterval J C; Hommels G; Teeuwsen J; Bult A; Lingeman H; Underberg W J
Quantitative analysis of pharmaceutically active peptides using on-capillary analyte preconcentration transient isotachophoresis.
Electrophoresis 2000;21(14):2851-8.
2000: Nuijen B; Bouma M; Henrar R E; Floriano P; Jimeno J M; Talsma H; Kettenes-van den Bosch J J; Heck A J; Bult A; Beijnen J H
Pharmaceutical development of a parenteral lyophilized formulation of the novel antitumor agent aplidine.
PDA journal of pharmaceutical science and technology / PDA 2000;54(3):193-208.
2000: Nuijen B; Bouma M; Henrar R E; Brauns U; Bette P; Bult A; Beijnen J H
In vitro biocompatibility studies with the experimental anticancer agent BIBX1382BS.
International journal of pharmaceutics 2000;194(2):261-7.
2000: Hoitink M A; Beijnen J H; Bult A; Damen J M; van der Houwen O A; Kruijtzer J A; Tibben M M; Wiese G; Underberg W J
Degradation of azaglycinamido residues in model tripeptides derived from goserelin.
Journal of pharmaceutical sciences 2000;89(1):108-14.
1999: Nuijen B; Bouma M; Henrar R E; Manada C; Bult A; Beijnen J H
Compatibility and stability of aplidine, a novel marine-derived depsipeptide antitumor agent, in infusion devices, and its hemolytic and precipitation potential upon i.v. administration.
Anti-cancer drugs 1999;10(10):879-87.
1999: Waterval J C; Krabbe H; Teeuwsen J; Bult A; Lingeman H; Underberg W J
Comparison between transient isotachophoretic capillary zone electrophoresis and reversed-phase liquid chromatography for the determination of peptides in plasma.
Electrophoresis 1999;20(14):2909-16.
1999: Sluiter C; Kettenes-van den Bosch J J; Hop E; van der Houwen O A; Underberg W J; Bult A
Degradation study of the investigational anticancer drug clanfenur.
International journal of pharmaceutics 1999;185(2):227-35.
1999: Léon J; Reubsaet E; Beijnen J H; van Bennekom W P; Bult A; Hoekstra A J; Hop E; van Os P J; Teeuwsen J; Underberg W J
Reduction of Cys36-Cys42 and Cys64-Cys74 disulfide bonds in recombinant human granulocyte colony stimulating factor.
Journal of pharmaceutical and biomedical analysis 1999;19(6):837-45.
1999: Rosing H; van Zomeren D M; Doyle E; ten Bokkel W W; Schellens J H; Bult A; Beijnen J H
Quantification of topotecan and its metabolite N-desmethyltopotecan in human plasma, urine and faeces by high-performance liquid chromatographic methods.
Journal of chromatography. B, Biomedical sciences and applications 1999;727(1-2):191-203.
1999: Reubsaet J L; Beijnen J H; Belshof E H; Bouyakhrichan M; Bult A; Hop E; Kellekule Y; van Maanen R J; Teeuwsen J; Underberg W J
Qualitative and quantitative aspects of the degradation of several tripeptides derived from the antitumour peptide antagonist [Arg(6), D-Trp(7,9), MePhe(8)] substance P[6-11].
Journal of pharmaceutical and biomedical analysis 1999;19(3-4):277-84.
1999: Rosing H; ten Bokkel Huinink W W; van Gijn R; Rombouts R F; Bult A; Beijnen J H
Comparative open, randomized, cross-over bioequivalence study of two intravenous dexrazoxane formulations (Cardioxane and ICRF-187) in patients with advanced breast cancer, treated with 5-fluorouracil-doxorubicin-cyclophosphamide (FDC).
European journal of drug metabolism and pharmacokinetics 1999;24(1):69-77.
1999: van Gijn R; van Tellingen O; Haverkate E; Kettenes-van den Bosch J J; Bult A; Beijnen J H
Pharmacokinetics and metabolism of the staurosporine analogue CGP 41 251 in mice.
Investigational new drugs 1999;17(1):29-41.
1998: Waterval J C; la Porte C J; van 't Hof R; Teeuwsen J; Bult A; Lingeman H; Underberg W J
Development and validation of transient isotachophoretic capillary zone electrophoresis for determination of peptides.
Electrophoresis 1998;19(18):3171-7.
1998: Rosing H; Hillebrand M J; Jimeno J M; Gómez A; Floriano P; Faircloth G; Henrar R E; Vermorken J B; Cvitkovic E; Bult A; Beijnen J H
Quantitative determination of Ecteinascidin 743 in human plasma by miniaturized high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
Journal of mass spectrometry : JMS 1998;33(11):1134-40.
1998: Reubsaet J L; Beijnen J H; Bult A; van Maanen R J; Marchal J A; Underberg W J
Analytical techniques used to study the degradation of proteins and peptides: physical instability.
Journal of pharmaceutical and biomedical analysis 1998;17(6-7):979-84.
1998: Reubsaet J L; Beijnen J H; Bult A; van Maanen R J; Marchal J A; Underberg W J
Analytical techniques used to study the degradation of proteins and peptides: chemical instability.
Journal of pharmaceutical and biomedical analysis 1998;17(6-7):955-78.
1998: van Gijn R; Herben V M; Hillebrand M J; ten Bokkel Huinink W W; Bult A; Beijnen J H
High-performance liquid chromatographic analysis of the investigational anticancer drug 9-aminocamptothecin, as the lactone form and as the total of the lactone and the hydroxycarboxylate forms, in micro-volumes of human plasma.
Journal of pharmaceutical and biomedical analysis 1998;17(8):1257-65.
1998: Hoitink M A; Beijnen J H; Boschma M U; Bult A; van der Houwen O A; Wiese G; Underberg W J
Degradation kinetics of three gonadorelin analogues: developing a method for calculating epimerization parameters.
Pharmaceutical research 1998;15(9):1449-55.
1998: Rosing H; van Zomeren D M; Doyle E; Bult A; Beijnen J H
O-glucuronidation, a newly identified metabolic pathway for topotecan and N-desmethyl topotecan.
Anti-cancer drugs 1998;9(7):587-92.
1998: Rosing H; Hillebrand M J; Jimeno J M; Gómez A; Floriano P; Faircloth G; Cameron L; Henrar R E; Vermorken J B; Bult A; Beijnen J H
Analysis of Ecteinascidin 743, a new potent marine-derived anticancer drug, in human plasma by high-performance liquid chromatography in combination with solid-phase extraction.
Journal of chromatography. B, Biomedical sciences and applications 1998;710(1-2):183-9.
1998: Reubsaet J L; Beijnen J H; Bult A; Hop E; Scholten S D; Teeuwsen J; Underberg W J
Oxidation of recombinant methionyl human granulocyte colony stimulating factor.
Journal of pharmaceutical and biomedical analysis 1998;17(2):283-9.
1998: Kaijser G P; De Kraker J; Bult A; Underberg W J; Beijnen J H
Pharmacokinetics of ifosfamide and some metabolites in children.
Anticancer research 1998;18(3B):1941-9.
1998: Wink T; van Zuilen S J; Bult A; van Bennekom W P
Liposome-mediated enhancement of the sensitivity in immunoassays of proteins and peptides in surface plasmon resonance spectrometry.
Analytical chemistry 1998;70(5):827-32.
1998: Jonkman-de Vries J D; Rosing H; Talsma H; Henrar R E; Kettenes-van den Bosch J J; Bult A; Beijnen J H
Pharmaceutical development of a parenteral lyophilized formulation of the investigational antitumor neuropeptide antagonist [Arg6, D-Trp7,9, MePhe8]-Substance P [6-11].
Investigational new drugs 1998;16(2):99-111.
1997: Bardelmeijer H A; Waterval J C; Lingeman H; van't Hof R; Bult A; Underberg W J
Pre-, on- and post-column derivatization in capillary electrophoresis.
Electrophoresis 1997;18(12-13):2214-27.
1997: Rongen H A; Bult A; van Bennekom W P
Liposomes and immunoassays.
Journal of immunological methods 1997;204(2):105-33.
1997: Wink T; van Zuilen S J; Bult A; van Bennkom W P
Self-assembled monolayers for biosensors.
The Analyst 1997;122(4):43R-50R.
1997: Kaijser G P; Ter Riet P G; de Kraker J; Bult A; Beijnen J H; Underberg W J
Determination of 4-hydroxyifosfamide in biological matrices by high-performance liquid chromatography.
Journal of pharmaceutical and biomedical analysis 1997;15(6):773-81.
1997: Jonkman-de Vries J D; Van den Bemt B J; ten Bokkel-Huinink W W; Underberg W J; Kettenes-van den Bosch J J; Henrar R E; Bult A; Beijnen J H
Pharmaceutical development of a parenteral formulation of the investigational anticancer drug clanfenur.
PDA journal of pharmaceutical science and technology / PDA 1997;51(2):89-95.
1997: Kaijser G P; Beijnen J H; Bult A; Keizer H J; Underberg W J
Chromatographic analysis of the enantiomers of ifosfamide and some of its metabolites in plasma and urine.
Journal of chromatography. B, Biomedical sciences and applications 1997;690(1-2):131-8.
1996: Kaijser G P; Beijnen J H; Rozendom E; Bult A; Underberg W J
Analysis of ifosforamide mustard, the active metabolite of ifosfamide, in plasma.
Journal of chromatography. B, Biomedical applications 1996;686(2):249-55.
1996: Vries J D; Doppenberg W G; Henrar R E; Bult A; Beijnen J H
Systematic study on the chemical stability of the prodrug antitumor agent carzelesin (U-80,244)
Journal of pharmaceutical sciences 1996;85(11):1227-33.
1996: Hoitink M A; Beijnen J H; Bult A; van der Houwen O A; Nijholt J; Underberg W J
Degradation kinetics of gonadorelin in aqueous solution.
Journal of pharmaceutical sciences 1996;85(10):1053-9.
1996: Rongen H A; van der Horst H M; van Oosterhout A J; Bult A; van Bennekom W P
Application of xanthine oxidase-catalyzed luminol chemiluminescence in a mouse interleukin-5 immunoassay.
Journal of immunological methods 1996;197(1-2):161-9.
1996: Kaijser G P; Keizer H J; Beijnen J H; Bult A; Underberg W J
Pharmacokinetics of ifosfamide, 2- and 3-dechloroethylifosfamide in plasma and urine of cancer patients treated with a 10-day continuous infusion of ifosfamide.
Anticancer research 1996;16(5B):3247-57.
1996: Cui H; Reubsaet J L; Bult A
Precolumn fluorescence derivatization of the antagonist [Arg6,D-Trp7,9,MePhe8]-substance P[6-11] with benzoin in high-performance liquid chromatography and selective detection of arginine-containing fragments in its degradation products.
Journal of chromatography. A 1996;736(1-2):91-6.
1996: Jonkman-de Vries J D; Kettenes-van den Bosch J J; Henrar R E; Bult A; Beijnen J H
Purity determinations in the bulk drug of the novel indoloquinone antitumor agent EO9.
Investigational new drugs 1996;14(2):181-91.
1995: Reubsaet J L; Beijnen J H; Bult A; Hop E; Vermaas R; Kellekule Y; Kettenes-van den Bosch J J; Underberg W J
Structural identification of the degradation products of the antitumor peptide antagonist [Arg6,D-Trp7,9,MePhe8]substance P (6-11).
Analytical chemistry 1995;67(23):4431-6.
1995: Jonkman-De Vries J D; Rosing H; Henrar R E; Bult A; Beijnen J H
The influence of formulation excipients on the stability of the novel antitumor agent carzelesin (U-80,244).
PDA journal of pharmaceutical science and technology / PDA 1995;49(6):283-8.
1995: Reubsaet J L; Beijnen J H; Bult A; van der Houwen O A; Teeuwsen J; Koster E H; Underberg W J
Degradation kinetics of antagonist [Arg6, D-Trp7,9, MePhe8]-substance P [6-11] in aqueous solutions.
Analytical biochemistry 1995;227(2):334-41.
1994: Reubsaet J L; Beijnen J H; Bult A; Teeuwsen J; Koster E H; Waterval J C; Underberg W J
Reversed-phase high-performance liquid chromatography and capillary electrophoresis in the stability study of the neuropeptide growth factor antagonist [Arg6,D-Trp7,9,MePhe8]-substance P (6-11): a comparative study.
Analytical biochemistry 1994;220(1):98-102.
1994: Rongen H A; Hoetelmans R M; Bult A; van Bennekom W P
Chemiluminescence and immunoassays.
Journal of pharmaceutical and biomedical analysis 1994;12(4):433-62.
1994: Kaijser G P; Beijnen J H; Bult A; Underberg W J
Ifosfamide metabolism and pharmacokinetics (review).
Anticancer research 1994;14(2A):517-31.
1994: van Tellingen O; Sonneveldt A L; Beijnen J H; Nooijen W J; Kettenes-van den Bosch J J; Versluis C; Bult A
Plasma pharmacokinetics, tissue disposition, excretion and metabolism of vinleucinol in mice as determined by high-performance liquid chromatography.
Cancer chemotherapy and pharmacology 1994;33(5):425-34.
1994: Jonkman-de Vries J D; Talsma H; Henrar R E; Kettenes-van den Bosch J J; Bult A; Beijnen J H
Pharmaceutical development of a parenteral lyophilized formulation of the novel indoloquinone antitumor agent EO9.
Cancer chemotherapy and pharmacology 1994;34(5):416-22.
1994: Jonkman-de Vries J D; de Graaff-Teulen M J; Henrar R E; Kettenes-van den Bosch J J; Bult A; Beijnen J H
Pharmaceutical development of a parenteral formulation of the novel anti-tumor agent carzelesin (U-80,244).
Investigational new drugs 1994;12(4):303-14.
1993: Kaijser G P; Korst A; Beijnen J H; Bult A; Underberg W J
The analysis of ifosfamide and its metabolites (review).
Anticancer research 1993;13(5A):1311-24.
1993: van Tellingen O; Beijnen J H; Nooijen W J; Bult A
Plasma pharmacokinetics of vinblastine and the investigational Vinca alkaloid N-(deacetyl-O-4-vinblastoyl-23)-L-ethyl isoleucinate in mice as determined by high-performance liquid chromatography.
Cancer research 1993;53(9):2061-5.
1993: Kaijser G P; Beijnen J H; Jeunink E L; Bult A; Keizer H J; de Kraker J; Underberg W J
Determination of chloroacetaldehyde, a metabolite of oxazaphosphorine cytostatic drugs, in plasma.
Journal of chromatography 1993;614(2):253-9.
1993: van Tellingen O; Kuijpers A V; Beijnen J H; Nooijen W J; Bult A
Plasma pharmacokinetics, tissue disposition, excretion and metabolism of vinorelbine in mice as determined by high performance liquid chromatography.
Investigational new drugs 1993;11(2-3):141-50.
1993: van Tellingen O; Beijnen J H; Nooijen W J; Bult A
Tissue disposition, excretion and metabolism of vinblastine in mice as determined by high-performance liquid chromatography.
Cancer chemotherapy and pharmacology 1993;32(4):286-92.
1992: Kaijser G P; Beijnen J H; Bult A; Wiese G; de Kraker J; Keizer H J; Underberg W J
Gas chromatographic determination of 2- and 3-dechloroethylifosfamide in plasma and urine.
Journal of chromatography 1992;583(2):175-82.
1992: van Tellingen O; Sips J H; Beijnen J H; Bult A; Nooijen W J
Pharmacology, bio-analysis and pharmacokinetics of the vinca alkaloids and semi-synthetic derivatives (review).
Anticancer research 1992;12(5):1699-715.
1992: Halvax J J; Wiese G; Van Bennekom W P; Bult A
On-line phase-transfer catalysed dansylation of phenolic compounds followed by normal-phase liquid chromatography with fluorescence detection.
Journal of pharmaceutical and biomedical analysis 1992;10(5):335-41.
1991: Kaijser G P; Beijnen J H; Bult A; Wiese G; de Kraker J; Underberg W J
Gas chromatographic determination of ifosfamide in microvolumes of urine and plasma.
Journal of chromatography 1991;571(1-2):121-31.
1991: Kaijser G P; Beijnen J H; Bult A; Hogeboom M H; Underberg W J
A systematic study on the chemical stability of ifosfamide.
Journal of pharmaceutical and biomedical analysis 1991;9(10-12):1061-7.
1991: Bekers O; Beijnen J H; Tank M J; Bult A; Underberg W J
Effect of cyclodextrins on the chemical stability of mitomycins in alkaline solution.
Journal of pharmaceutical and biomedical analysis 1991;9(10-12):1055-60.
1990: van Opstal M A; Wolters R; Blauw J S; van Krimpen P C; van Bennekom W P; Bult A
Determination of penicillin in pharmaceutical formulations by flow injection analysis using an optimised immobilised penicillinase reactor and iodometric detection.
Journal of pharmaceutical and biomedical analysis 1990;8(1):49-60.
1990: Bekers O; Beijnen J H; Otagiri M; Bult A; Underberg W J
Inclusion complexation of doxorubicin and daunorubicin with cyclodextrins.
Journal of pharmaceutical and biomedical analysis 1990;8(8-12):671-4.
1990: Halvax J J; Wiese G; Arp J A; Vermeer J M; van Bennekom W P; Bult A
Rapid determination of benzalkonium chloride in pharmaceutical preparations with flow injection liquid-liquid extraction.
Journal of pharmaceutical and biomedical analysis 1990;8(3):243-52.
1989: van Opstal M A; van der Horst F A; Holthuis J J; van Bennekom W P; Bult A
Automated reversed-phase chromatographic analysis of etoposide and teniposide in plasma by using on-line surfactant-mediated sample clean-up and column-switching.
Journal of chromatography 1989;495():139-51.
1988: Van Krimpen P C; Van Bennekom W P; Bult A
A study of the metal complexation behaviour of some penicillins, cephalosporins and their derivatives.
Pharmaceutisch weekblad. Scientific edition 1988;10(6):259-66.
1988: van Opstal M A; Krabbenborg P; Holthuis J J; van Bennekom W P; Bult A
Comparison of flow-injection analysis with high-performance liquid chromatography for the determination of etoposide in plasma.
Journal of chromatography 1988;432():385-400.
1987: Dingjan H A; Van Bennekom W P; Bult A
Polarographic determination of extraction constants.
Pharmaceutisch weekblad. Scientific edition 1987;9(4):198-202.
1987: Dreijer-van der Glas S M; Bult A
Incompatibility of indometacin and benzalkonium in eye drops due to ion-pair formation.
Pharmaceutisch weekblad. Scientific edition 1987;9(1):29-32.
1987: Van Krimpen P C; Van Bennekom W P; Bult A
Penicillins and cephalosporins. Physicochemical properties and analysis in pharmaceutical and biological matrices.
Pharmaceutisch weekblad. Scientific edition 1987;9(1):1-23.
1985: Bult A; Dingjan H A; Dreijer-van der Glas S M; Van Bennekom W P
Generalized theory for two-phase ion-pair and complexometric titrations. II. Two-phase titrations with side reactions.
Pharmaceutisch weekblad. Scientific edition 1985;7(6):267-72.
1985: Bult A; Dingjan H A; Dreijer-van der Glas S M; Van Bennekom W P
Generalized theory for two-phase ion-pair and complexometric titrations. I. Two-phase titrations without side reactions.
Pharmaceutisch weekblad. Scientific edition 1985;7(6):260-6.
1984: Leeuwenkamp O R; Van Bennekom W P; Van der Mark E J; Bult A
Nitroprusside, antihypertensive drug and analytical reagent. Review of (photo)stability, pharmacology and analytical properties.
Pharmaceutisch weekblad. Scientific edition 1984;6(4):129-40.
1983: Dreijer-Van Der Glas S M; Schalekamp T; De Jong H J; Bult A
Determination of phenol in the presence of resorcinol applying substitution with excess bromine water; structure of the bromination products.
Pharmaceutisch weekblad. Scientific edition 1983;5(2):70-3.

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