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Geert Maertens

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Babs E Verstrepen; François L Cosset; Erik Depla; Marlène Dreux; Joost A R Drexhage; Christelle Granier; Gerrit Koopman; Geert Maertens; Gwenny Mares; Sofie Priem; Christine Rollier; Ernst J Verschoor; Jonathan Luke Heeney
Clearance of genotype 1b hepatitis C virus in chimpanzees in the presence of vaccine-induced E1-neutralizing antibodies.
Mário G Pessôa; Venâncio A F Alves; Alda Wakamatsu; Joaquim G Gomes; Geert Maertens; Bart van der Borght; Michael Kim; Linda Ferrell; Teresa L Wright
Post-transplant recurrent hepatitis C: immunohistochemical detection of hepatitis C virus core antigen and possible pathogenic implications.
Yves Rouillé; François Helle; David Delgrange; Philippe Roingeard; Cécile Voisset; Emmanuelle Blanchard; Sandrine Belouzard; Jane A McKeating; Arvind H Patel; Geert Maertens; Takaji Wakita; Czeslaw Wychowski; Jean Dubuisson
Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus.

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All Publications

2011: Babs E Verstrepen; François L Cosset; Erik Depla; Marlène Dreux; Joost A R Drexhage; Christelle Granier; Gerrit Koopman; Geert Maertens; Gwenny Mares; Sofie Priem; Christine Rollier; Ernst J Verschoor; Jonathan Luke Heeney
Clearance of genotype 1b hepatitis C virus in chimpanzees in the presence of vaccine-induced E1-neutralizing antibodies.
The Journal of infectious diseases 2011;204(6):837-44.
2008: Mário G Pessôa; Venâncio A F Alves; Alda Wakamatsu; Joaquim G Gomes; Geert Maertens; Bart van der Borght; Michael Kim; Linda Ferrell; Teresa L Wright
Post-transplant recurrent hepatitis C: immunohistochemical detection of hepatitis C virus core antigen and possible pathogenic implications.
Liver international : official journal of the International Association for the Study of the Liver 2008;28(6):807-13.
2006: Yves Rouillé; François Helle; David Delgrange; Philippe Roingeard; Cécile Voisset; Emmanuelle Blanchard; Sandrine Belouzard; Jane A McKeating; Arvind H Patel; Geert Maertens; Takaji Wakita; Czeslaw Wychowski; Jean Dubuisson
Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus.
Journal of virology 2006;80(6):2832-41.
2005: Peter Simmonds; Jens Bukh; Christophe Combet; Gilbert Deléage; Nobuyuki Enomoto; Stephen Feinstone; Phillippe Halfon; Geneviève Inchauspé; Carla Kuiken; Geert Maertens; Masashi Mizokami; Donald G Murphy; Hiroaki Okamoto; Jean-Michel Pawlotsky; François Penin; Erwin Sablon; Tadasu Shin-i; Lieven Stuyver; Heinz-Jürgen Thiel; Sergei Viazov; Amy J Weiner; Anders Widell
Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes.
Hepatology (Baltimore, Md.) 2005;42(4):962-73.
2005: Dale Netski; Timothy Mosbruger; Erik Depla; Geert Maertens; Stuart C Ray; Robert G Hamilton; Stacy Roundtree; David L Thomas; Jane A McKeating; Andrea L Cox
Humoral immune response in acute hepatitis C virus infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005;41(5):667-75.
2005: Geert Leroux-Roels; Arsène-Hélène Batens; Isabelle Desombere; Bart Van Den Steen; Christine Vander Stichele; Geert Maertens; Frank Hulstaert
Immunogenicity and tolerability of intradermal administration of an HCV E1-based vaccine candidate in healthy volunteers and patients with resolved or ongoing chronic HCV infection.
Human vaccines 2005;1(2):61-5.
2004: Daniel Steinmann; Heidi Barth; Bettina Gissler; Peter Schürmann; Mohammed I Adah; J Tilman Gerlach; Gerd R Pape; Erik Depla; Dirk Jacobs; Geert Maertens; Arvind H Patel; Geneviève Inchauspé; TSANYANG LIANG; Hubert E Blum; Thomas F Baumert
Inhibition of hepatitis C virus-like particle binding to target cells by antiviral antibodies in acute and chronic hepatitis C.
Journal of virology 2004;78(17):9030-40.
2004: Geert Leroux-Roels; Erik Depla; Frank Hulstaert; Leen Tobback; Stéphanie Dincq; Jaques Desmet; Isabelle Desombere; Geert Maertens
A candidate vaccine based on the hepatitis C E1 protein: tolerability and immunogenicity in healthy volunteers.
Vaccine 2004;22(23-24):3080-6.
2004: Sija De Gendt; Fred Shapiro; Jelena Juras; Els Van Assche; Geert Maertens; Erwin Sablon
Hepatitis B viral genotyping with the research INNO-LiPA HBV genotyping line probe assay.
Methods in molecular medicine 2004;95():175-86.
2004: Christine Rollier; Erik Depla; Joost A R Drexhage; Ernst J Verschoor; Babs E Verstrepen; Ahmed Fatmi; C Brinster; Anne Fournillier; J A Whelan; Mike Whelan; Dirk Jacobs; Geert Maertens; Geneviève Inchauspé; Jonathan Luke Heeney
Control of heterologous hepatitis C virus infection in chimpanzees is associated with the quality of vaccine-induced peripheral T-helper immune response.
Journal of virology 2004;78(1):187-96.
2003: Frederik Nevens; Tania Roskams; Hans Van Vlierberghe; yves horsmans; Dave Sprengers; Ann Elewaut; Valeer Desmet; Geert Leroux-Roels; Emmanuel Quinaux; Erik Depla; Stephanie Dincq; Christine Vander Stichele; Geert Maertens; Frank Hulstaert
A pilot study of therapeutic vaccination with envelope protein E1 in 35 patients with chronic hepatitis C.
Hepatology (Baltimore, Md.) 2003;38(5):1289-96.
2003: Chris Verslype; Frederik Nevens; Nicoletta Sinelli; Carine Clarysse; Jacques Pirenne; Erik Depla; Geert Maertens; Jos van Pelt; Valeer Desmet; Johan Fevery; Tania Roskams
Hepatic immunohistochemical staining with a monoclonal antibody against HCV-E2 to evaluate antiviral therapy and reinfection of liver grafts in hepatitis C viral infection.
Journal of hepatology 2003;38(2):208-14.
2002: Anna S F Lok; Fabien Zoulim; Stephen Locarnini; alessandra mangia; Grazia Anna Niro; Hilde Decraemer; Geert Maertens; Frank Hulstaert; Karen De Vreese; Erwin Sablon
Monitoring drug resistance in chronic hepatitis B virus (HBV)-infected patients during lamivudine therapy: evaluation of performance of INNO-LiPA HBV DR assay.
Journal of clinical microbiology 2002;40(10):3729-34.
2002: Saadia Bichr; Rosanna Rende-Fournier; Giovanna Vona; Ana-Maria Yamamoto; Erik Depla; Geert Maertens; Christian Bréchot
Detection of neutralizing antibodies to hepatitis C virus using a biliary cell infection model.
The Journal of general virology 2002;83(Pt 7):1673-8.
2002: Cosme Alvarado Esquivel; Ann E Elewaut; Jan Philippé; Ann E Elewaut; Isabelle Desombere; Geert Maertens; Geert Leroux-Roels
Evolution of hepatitis C virus-specific T cell responses and cytokine production in chronic hepatitis C patients treated with high doses of interferon-alpha.
Revista de investigación clínica; organo del Hospital de Enfermedades de la Nutrición 2002;54(1):41-50.
2001: C Laurent; D Henzel; C Mulanga-Kabeya; Geert Maertens; Bernard Larouzé; Eric Delaporte
Seroepidemiological survey of hepatitis C virus among commercial sex workers and pregnant women in Kinshasa, Democratic Republic of Congo.
International journal of epidemiology 2001;30(4):872-7.
2001: F Querenghi; Q Yu; G Billaud; Geert Maertens; Christian Trépo; Fabien Zoulim
Evolution of hepatitis C virus genome in chronically infected patients receiving ribavirin monotherapy.
Journal of viral hepatitis 2001;8(2):120-31.
2000: A Takaki; M Wiese; Geert Maertens; Erik Depla; Ulrike Seifert; A Liebetrau; J L Miller; Michael P Manns; Barbara Rehermann
Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C.
Nature medicine 2000;6(5):578-82.
2000: Geert Maertens; S Priem; A Ducatteeuw; E Verschoorl; Babs E Verstrepen; T Roskams; Valeer Desmet; S Fuller; K van Hoek; P Vandeponseele; F Bosman; M A Buyse; Leen-Jan van Doorn; Jonathan Luke Heeney; A Kos; Erik Depla
Improvement of chronic active hepatitis C in chronically infected chimpanzees after therapeutic vaccination with the HCV E1 protein.
Acta gastro-enterologica Belgica 2000;63(2):203.
2000: S De Meyer; ZJ Gong; K Hertogs; Erik Depla; Jos F van Pelt; Tania Roskams; Geert Maertens; Sing Hiem Yap
Influence of the administration of human annexin V on in vitro binding of small hepatitis B surface antigen to human and to rat hepatocytes and on in vitro hepatitis B virus infection.
Journal of viral hepatitis 2000;7(2):104-14.
2000: S Depraetere; E Van Kerschaever; Hans Van Vlierberghe; Ann Elewaut; Johannes T Brouwer; H G Niesters; Solko W Schalm; Geert Maertens; Geert Leroux-Roels
Long term response to interferon treatment in chronic hepatitis C patients is associated with a significant reduction in anti-E1 envelope antibody titers.
Journal of medical virology 2000;60(2):126-32.
1999: S De Meyer; Z Gong; Erik Depla; Geert Maertens; Sing Hiem Yap
Involvement of phosphatidylserine and non-phospholipid components of the hepatitis B virus envelope in human Annexin V binding and in HBV infection in vitro.
Journal of hepatology 1999;31(5):783-90.
1999: Anne Fournillier; Erik Depla; P Karayiannis; O Vidalin; Geert Maertens; Christian Trépo; Geneviève Inchauspé
Expression of noncovalent hepatitis C virus envelope E1-E2 complexes is not required for the induction of antibodies with neutralizing properties following DNA immunization.
Journal of virology 1999;73(9):7497-504.
1999: S De Meyer; Erik Depla; Geert Maertens; A Soumillion; Sing Hiem Yap
Characterization of small hepatitis B surface antigen epitopes involved in binding to human annexin V.
Journal of viral hepatitis 1999;6(4):277-85.
1999: Matthew E Cramp; P Carucci; Siegbert Rossol; Shilpa Chokshi; Geert Maertens; Roger Williams; Nikolai Naoumov
Hepatitis C virus (HCV) specific immune responses in anti-HCV positive patients without hepatitis C viraemia.
Gut 1999;44(3):424-9.
1999: Edward Gane; Geert Maertens; A Ducatteeuw; K P Qian; J Y Lau; H Jones; E Davies; Nikolai Naoumov; Roger Williams
Antibodies to hepatitis C virus envelope proteins correlate with hepatitis C viraemia after liver transplantation.
Transplantation 1999;67(1):78-84.
1999: Geert Maertens; L Stuyver
HCV Genotyping by the Line Probe Assay INNO-LiPA HCV II.
Methods in molecular medicine 1999;19():183-98.
1999: Geert Maertens; F Dekeyser; A Van Geel; E Sablon; F Bosman; M Zrein; D Pollet
Confirmation of HCV Antibodies by the Line Immunoassay INNO-LIA HCV Ab III.
Methods in molecular medicine 1999;19():11-25.
1998: Anne Fournillier; I Nakano; L Vitvitski; Erik Depla; O Vidalin; Geert Maertens; Christian Trépo; Geneviève Inchauspé
Modulation of immune responses to hepatitis C virus envelope E2 protein following injection of plasmid DNA using single or combined delivery routes.
Hepatology (Baltimore, Md.) 1998;28(1):237-44.
1998: D Jeannel; C Fretz; Y Traore; N Kohdjo; A Bigot; E Pê Gamy; G Jourdan; K Kourouma; Geert Maertens; F Fumoux; JJ Fournel; Lieven Stuyver
Evidence for high genetic diversity and long-term endemicity of hepatitis C virus genotypes 1 and 2 in West Africa.
Journal of medical virology 1998;55(2):92-7.
1998: Françoise Lunel; Lieven Stuyver; Christian Brechot; Geert Maertens
[Update on hepatitis C virus: its variability and the implications].
Transfusion clinique et biologique : journal de la Société française de transfusion sanguine 1998;5(2):147-65.
1998: B Robertson; G Myers; C Howard; T Brettin; Jens Bukh; B Gaschen; Takashi Gojobori; Geert Maertens; M Mizokami; Omana V Nainan; S Netesov; K Nishioka; Tadasu Shin-i; P Simmonds; D Smith; Lieven Stuyver; A Weiner
Classification, nomenclature, and database development for hepatitis C virus (HCV) and related viruses: proposals for standardization. International Committee on Virus Taxonomy.
Archives of virology 1998;143(12):2493-503.
1998: Leda Bassit; Bernhard Kleter; Gabriela Ribeiro-Dos-Santos; Geert Maertens; Ester Sabino; Dalton F Chamone; W Quint; Amadeo Sáez-Alquézar
Hepatitis G virus: prevalence and sequence analysis in blood donors of São Paulo, Brazil.
Vox sanguinis 1998;74(2):83-7.
1997: I Nakano; Geert Maertens; ME Major; L Vitvitski; Jean Dubuisson; Anne Fournillier; G De Martynoff; Christian Trepo; G Inchauspe
Immunization with plasmid DNA encoding hepatitis C virus envelope E2 antigenic domains induces antibodies whose immune reactivity is linked to the injection mode.
Journal of virology 1997;71(9):7101-9.
1997: Nikolai Naoumov; Shilpa Chokshi; E Metivier; Geert Maertens; P J Johnson; Roger Williams
Hepatitis C virus infection in the development of hepatocellular carcinoma in cirrhosis.
Journal of hepatology 1997;27(2):331-6.
1997: Leen-Jan van Doorn; K van Hoek; G de Martinoff; F Bosman; Lieven Stuyver; T Kos; I Frantzen; P Sillekens; Geert Maertens; Wim Quint
Serological and molecular analysis of hepatitis C virus envelope regions 1 and 2 during acute and chronic infections in chimpanzees.
Journal of medical virology 1997;52(4):441-50.
1997: alessandra mangia; I Cascavilla; G Lezzi; Fulvio Spirito; Geert Maertens; L Parlatore; Giorgio Saracco; Mario Rizzetto; Angelo Andriulli
HCV genotypes in patients with liver disease of different stages and severity.
Journal of hepatology 1997;26(6):1173-8.
1997: Jean-Louis Bosmans; Etienne J Nouwen; Geert J Behets; K Gorteman; Sameer Huraib; Faissal A M Shaheen; Geert Maertens; Gert A Verpooten; Monique M Elseviers; Marc E De Broe
Prevalence and clinical expression of HCV-genotypes in haemodialysis-patients of two geographically remote countries: Belgium and Saudi-Arabia.
Clinical nephrology 1997;47(4):256-62.
1996: K L Lindsay; Gary L Davis; Eugene R Schiff; Henry Jr. Bodenheimer; L A Balart; Jules L Dienstag; Robert P Perrillo; C H Tamburro; J S Goff; G T Everson; M Silva; W N Katkov; Z Goodman; Johnson Y N Lau; Geert Maertens; J Gogate; B Sanghvi; J Albrecht
Response to higher doses of interferon alfa-2b in patients with chronic hepatitis C: a randomized multicenter trial. Hepatitis Interventional Therapy Group.
Hepatology (Baltimore, Md.) 1996;24(5):1034-40.
1996: Lieven Stuyver; A Wyseur; W van Arnhem; F Hernandez; Geert Maertens
Second-generation line probe assay for hepatitis C virus genotyping.
Journal of clinical microbiology 1996;34(9):2259-66.
1996: Lieven Stuyver; C Fretz; C Esquivel; A Boudifa; D Jaulmes; Nabih Azar; Françoise Lunel; Geert Leroux-Roels; Geert Maertens; J J Fournel
Hepatitis C virus (HCV) genotype analysis in apparently healthy anti-HCV-positive Parisian blood donors.
Transfusion 1996;36(6):552-8.
1996: Johnson Y N Lau; Gary L Davis; L E Prescott; Geert Maertens; K L Lindsay; K Qian; M Mizokami; P Simmonds
Distribution of hepatitis C virus genotypes determined by line probe assay in patients with chronic hepatitis C seen at tertiary referral centers in the United States. Hepatitis Interventional Therapy Group.
Annals of internal medicine 1996;124(10):868-76.
1996: Edward Gane; Bernard Portmann; Nikolai Naoumov; H M Smith; James Underhill; Peter T Donaldson; Geert Maertens; Roger Williams
Long-term outcome of hepatitis C infection after liver transplantation.
The New England journal of medicine 1996;334(13):815-20.
1996: Lieven Stuyver; H Claeys; A Wyseur; W Van Arnhem; Hans De Beenhouwer; S Uytendaele; J Beckers; D Matthijs; Geert Leroux-Roels; Geert Maertens; M De Paepe
Hepatitis C virus in a hemodialysis unit: molecular evidence for nosocomial transmission.
Kidney international 1996;49(3):889-95.
1996: Geert Leroux-Roels; C A Esquivel; Robert DeLeys; Lieven Stuyver; A Elewaut; Jan Philippé; Isabelle Desombere; J Paradijs; Geert Maertens
Lymphoproliferative responses to hepatitis C virus core, E1, E2, and NS3 in patients with chronic hepatitis C infection treated with interferon alfa.
Hepatology (Baltimore, Md.) 1996;23(1):8-16.
1996: Edward Gane; Nikolai Naoumov; K P Qian; M U Mondelli; Geert Maertens; Bernard Portmann; Johnson Y N Lau; Roger Williams
A longitudinal analysis of hepatitis C virus replication following liver transplantation.
Gastroenterology 1996;110(1):167-77.
1995: G E Kleter; Leen-Jan van Doorn; Lieven Stuyver; Geert Maertens; Johannes T Brouwer; Solko W Schalm; Rudolf Heijtink; Wim Quint
Rapid genotyping of hepatitis C virus RNA-isolates obtained from patients residing in western Europe.
Journal of medical virology 1995;47(1):35-42.
1995: Carlo Giannini; Valérie Thiers; J B Nousbaum; Lieven Stuyver; Geert Maertens; Christian Bréchot
Comparative analysis of two assays for genotyping hepatitis C virus based on genotype-specific primers or probes.
Journal of hepatology 1995;23(3):246-53.
1995: Leen-Jan van Doorn; G E Kleter; Lieven Stuyver; Geert Maertens; Johannes T Brouwer; Solko W Schalm; Rudolf Heijtink; Wim Quint
Sequence analysis of hepatitis C virus genotypes 1 to 5 reveals multiple novel subtypes in the Benelux countries.
The Journal of general virology 1995;76 ( Pt 7)():1871-6.
1995: Cyrille Féray; Michele Gigou; Didier Samuel; V Paradis; S Mishiro; Geert Maertens; M Reynés; H Okamoto; Henri Bismuth; Christian Bréchot
Influence of the genotypes of hepatitis C virus on the severity of recurrent liver disease after liver transplantation.
Gastroenterology 1995;108(4):1088-96.
1995: Leen-Jan van Doorn; I Capriles; Geert Maertens; Robert DeLeys; K Murray; T Kos; H Schellekens; Wim Quint
Sequence evolution of the hypervariable region in the putative envelope region E2/NS1 of hepatitis C virus is correlated with specific humoral immune responses.
Journal of virology 1995;69(2):773-8.
1995: Bart Vanderborght; C Rouzere; C F Ginuino; Geert Maertens; H Van Heuverswyn; Clara F T Yoshida
High prevalence of hepatitis C infection among Brazilian hemodialysis patients in Rio de Janeiro: a one-year follow-up study.
Revista do Instituto de Medicina Tropical de São Paulo 1995;37(1):75-9.
1994: K Mahaney; V Tedeschi; Geert Maertens; A M Di Bisceglie; John Vergalla; Jay H Hoofnagle; R Sallie
Genotypic analysis of hepatitis C virus in American patients.
Hepatology (Baltimore, Md.) 1994;20(6):1405-11.
1994: Lieven Stuyver; W van Arnhem; A Wyseur; F Hernandez; E Delaporte; Geert Maertens
Classification of hepatitis C viruses based on phylogenetic analysis of the envelope 1 and nonstructural 5B regions and identification of five additional subtypes.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):10134-8.
1994: Lieven Stuyver; W van Arnhem; A Wyseur; Geert Maertens
Cloning and phylogenetic analysis of the core, E2, and NS3/NS4 regions of the hepatitis C virus type 5a.
Biochemical and biophysical research communications 1994;202(3):1308-14.
1994: Leen-Jan van Doorn; Bernhard Kleter; Lieven Stuyver; Geert Maertens; H Brouwer; Solko W Schalm; Rudolf Heijtink; Wim Quint
Analysis of hepatitis C virus genotypes by a line probe assay and correlation with antibody profiles.
Journal of hepatology 1994;21(1):122-9.
1994: Leen-Jan van Doorn; Wim Quint; K Tsiquaye; J Voermans; D Paelinck; T Kos; Geert Maertens; H Schellekens; K Murray
Longitudinal analysis of hepatitis C virus infection and genetic drift of the hypervariable region.
The Journal of infectious diseases 1994;169(6):1226-35.
1994: Leen-Jan van Doorn; Bernhard Kleter; J Voermans; Geert Maertens; H Brouwer; Rudolf Heijtink; Wim Quint
Rapid detection of hepatitis C virus RNA by direct capture from blood.
Journal of medical virology 1994;42(1):22-8.
1993: Peter Vanlandschoot; Geert Maertens; Willy Min Jou; Walter Fiers
Recombinant secreted haemagglutinin protects mice against a lethal challenge of influenza virus.
Vaccine 1993;11(12):1185-7.
1993: Lieven Stuyver; Rudi Rossau; A Wyseur; M Duhamel; Bart Vanderborght; H Van Heuverswyn; Geert Maertens
Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay.
The Journal of general virology 1993;74 ( Pt 6)():1093-102.
1993: Lieven Stuyver; W Van Arnhem; A Wyseur; Robert DeLeys; Geert Maertens
Analysis of the putative E1 envelope and NS4a epitope regions of HCV type 3.
Biochemical and biophysical research communications 1993;192(2):635-41.
1993: Bart Vanderborght; A M Reis; C D Rouzere; R S da Silva; Clara F T Yoshida; L G Franco; Geert Maertens; H Van Heuverswijn; J Moreira Pereira
Prevalence of anti-hepatitis C virus in the blood donor population of Rio de Janeiro.
Vox sanguinis 1993;65(2):122-5.
1992: Leen-Jan van Doorn; Alex Van Belkum; Geert Maertens; Wim Quint; T Kos; H Schellekens
Hepatitis C virus antibody detection by a line immunoassay and (near) full length genomic RNA detection by a new RNA-capture polymerase chain reaction.
Journal of medical virology 1992;38(4):298-304.
1989: Christian R De Potter; JR Quatacker; Geert Maertens; S Van Daele; C Pauwels; C Verhofstede; W Eechaute; H Roels
The subcellular localization of the neu protein in human normal and neoplastic cells.
International journal of cancer. Journal international du cancer 1989;44(6):969-74.
1989: Christian R De Potter; S Van Daele; M J Van de Vijver; C Pauwels; Geert Maertens; J De Boever; D Vandekerckhove; H Roels
The expression of the neu oncogene product in breast lesions and in normal fetal and adult human tissues.
Histopathology 1989;15(4):351-62.
1988: D Huylebroeck; Geert Maertens; M Verhoeyen; C Lopez; A Raeymakers; Willy Min Jou; Walter Fiers
High-level transient expression of influenza virus proteins from a series of SV40 late and early replacement vectors.
Gene 1988;66(2):163-81.