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Alistair Barber

Research Profile

Disorders

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Fluorescent Antibody Technique, Indirect

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Publications

TOP 3
Paul M Titchenell; Alistair Barber; H D Hollis Showalter; Yafei Jin; Jean-François Pons; David Antonetti
Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors.
Steven F Abcouwer; Cheng-mao Lin; Ellen B Wolpert; Sumathi Shanmugam; Eric W Schaefer; Willard M Freeman; Alistair Barber; David Antonetti
Effects of ischemic preconditioning and bevacizumab on apoptosis and vascular permeability following retinal ischemia-reperfusion injury.
Gregory R Jackson; Alistair Barber
Visual dysfunction associated with diabetic retinopathy.

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All Publications

2013: Paul M Titchenell; Alistair Barber; H D Hollis Showalter; Yafei Jin; Jean-François Pons; David Antonetti
Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors.
Bioorganic & medicinal chemistry letters 2013;23(10):3034-8.
2010: Steven F Abcouwer; Cheng-mao Lin; Ellen B Wolpert; Sumathi Shanmugam; Eric W Schaefer; Willard M Freeman; Alistair Barber; David Antonetti
Effects of ischemic preconditioning and bevacizumab on apoptosis and vascular permeability following retinal ischemia-reperfusion injury.
Investigative ophthalmology & visual science 2010;51(11):5920-33.
2010: Gregory R Jackson; Alistair Barber
Visual dysfunction associated with diabetic retinopathy.
Current diabetes reports 2010;10(5):380-4.
2010: Willard M Freeman; G V Bixler; Robert M Brucklacher; C-M Lin; Kruti M Patel; H D VanGuilder; Kathryn F Lanoue; Scot R Kimball; Alistair Barber; David Antonetti; Thomas Gardner; Sarah K Bronson
A multistep validation process of biomarkers for preclinical drug development.
The pharmacogenomics journal 2010;10(5):385-95.
2009: K J Paralikar; Thomas Neuberger; J T Matsui; Alistair Barber; Andrew Webb; Ryan Clement
Feasibility and safety of longitudinal magnetic resonance imaging in a rodent model with intracortical microwire implants.
Journal of neural engineering 2009;6(3):034001.
2009: Iwona Hirschler-Laszkiewicz; Qin Tong; Kathleen Conrad; Wenyi Zhang; Wesley W Flint; Alistair Barber; Dwayne Barber; Joseph Y Cheung; Barbara A Miller
TRPC3 activation by erythropoietin is modulated by TRPC6.
The Journal of biological chemistry 2009;284(7):4567-81.
2008: Steve F Abcouwer; Sumathi Shanmugam; Paul F Gomez; Sain Shushanov; Alistair Barber; Kathryn F Lanoue; Patrick G Quinn; Mark Kester; Thomas Gardner
Effect of IL-1beta on survival and energy metabolism of R28 and RGC-5 retinal neurons.
Investigative ophthalmology & visual science 2008;49(12):5581-92.
2008: Timothy S Kern; Alistair Barber
Retinal ganglion cells in diabetes.
The Journal of physiology 2008;586(Pt 18):4401-8.
2008: Heather D VanGuilder; Robert M Brucklacher; Kruti Patel; Rhona W Ellis; Willard M Freeman; Alistair Barber
Diabetes downregulates presynaptic proteins and reduces basal synapsin I phosphorylation in rat retina.
The European journal of neuroscience 2008;28(1):1-11.
2008: Matthew J Gastinger; Allen R Kunselman; Erin E Conboy; Sarah K Bronson; Alistair Barber
Dendrite remodeling and other abnormalities in the retinal ganglion cells of Ins2 Akita diabetic mice.
Investigative ophthalmology & visual science 2008;49(6):2635-42.
2007: Yuping Xu; M Shamsul Ola; Deborah A Berkich; Thomas Gardner; Alistair Barber; F Palmieri; Susan M Hutson; Kathryn F Lanoue
Energy sources for glutamate neurotransmission in the retina: absence of the aspartate/glutamate carrier produces reliance on glycolysis in glia.
Journal of neurochemistry 2007;101(1):120-31.
2006: David Antonetti; Alistair Barber; Sarah K Bronson; Willard M Freeman; Thomas Gardner; Leonard S Jefferson; Mark Kester; Scot R Kimball; J Kyle Krady; Kathryn F Lanoue; Christopher C Norbury; Patrick G Quinn; Lakshman Sandirasegarane; Ian A Simpson
Diabetic retinopathy: seeing beyond glucose-induced microvascular disease.
Diabetes 2006;55(9):2401-11.
2006: Ana R Santiago; Susana C Rosa; Paulo F Santos; Armando J Cristóvão; Alistair Barber; António F Ambrósio
Elevated glucose changes the expression of ionotropic glutamate receptor subunits and impairs calcium homeostasis in retinal neural cells.
Investigative ophthalmology & visual science 2006;47(9):4130-7.
2006: Matthew J Gastinger; Ravi S J Singh; Alistair Barber
Loss of cholinergic and dopaminergic amacrine cells in streptozotocin-diabetic rat and Ins2Akita-diabetic mouse retinas.
Investigative ophthalmology & visual science 2006;47(7):3143-50.
2006: Matthew J Gastinger; Alistair Barber; Noga Vardi; David Marshak
Histamine receptors in mammalian retinas.
The Journal of comparative neurology 2006;495(6):658-67.
2005: Alistair Barber; David Antonetti; Timothy S Kern; Chad E N Reiter; Rohit S Soans; J Kyle Krady; Steven W Levison; Thomas Gardner; Sarah K Bronson
The Ins2Akita mouse as a model of early retinal complications in diabetes.
Investigative ophthalmology & visual science 2005;46(6):2210-8.
2003: Alistair Barber; David Antonetti
Mapping the blood vessels with paracellular permeability in the retinas of diabetic rats.
Investigative ophthalmology & visual science 2003;44(12):5410-6.
2003: Chad E N Reiter; Lakshman Sandirasegarane; Ellen B Wolpert; Marianne Klinger; Ian A Simpson; Alistair Barber; David Antonetti; Mark Kester; Thomas Gardner
Characterization of insulin signaling in rat retina in vivo and ex vivo.
American journal of physiology. Endocrinology and metabolism 2003;285(4):E763-74.
2003: Alistair Barber
A new view of diabetic retinopathy: a neurodegenerative disease of the eye.
Progress in neuro-psychopharmacology & biological psychiatry 2003;27(2):283-90.
2002: Thomas Gardner; David Antonetti; Alistair Barber; Kathryn F Lanoue; Steven W Levison
Diabetic retinopathy: more than meets the eye.
Survey of ophthalmology 2002;47 Suppl 2():S253-62.
2002: Nicole S Harhaj; Alistair Barber; David Antonetti
Platelet-derived growth factor mediates tight junction redistribution and increases permeability in MDCK cells.
Journal of cellular physiology 2002;193(3):349-64.
2001: Kathryn F Lanoue; Deborah A Berkich; Myra Conway; Alistair Barber; L Y Hu; C Taylor; Susan M Hutson
Role of specific aminotransferases in de novo glutamate synthesis and redox shuttling in the retina.
Journal of neuroscience research 2001;66(5):914-22.
2001: M Nakamura; Alistair Barber; David Antonetti; Kathryn F Lanoue; K A Robinson; Maria G Buse; Thomas Gardner
Excessive hexosamines block the neuroprotective effect of insulin and induce apoptosis in retinal neurons.
The Journal of biological chemistry 2001;276(47):43748-55.
2001: Matthew J Gastinger; Alistair Barber; SA Khin; C S McRill; Thomas Gardner; David Marshak
Abnormal centrifugal axons in streptozotocin-diabetic rat retinas.
Investigative ophthalmology & visual science 2001;42(11):2679-85.
2001: Alistair Barber; M Nakamura; Ellen B Wolpert; Chad E N Reiter; Gail Seigel; David Antonetti; Thomas Gardner
Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3.
The Journal of biological chemistry 2001;276(35):32814-21.
2000: Alistair Barber; David Antonetti; Thomas Gardner
Altered expression of retinal occludin and glial fibrillary acidic protein in experimental diabetes. The Penn State Retina Research Group.
Investigative ophthalmology & visual science 2000;41(11):3561-8.
2000: E Lieth; Thomas Gardner; Alistair Barber; David Antonetti
Retinal neurodegeneration: early pathology in diabetes.
Clinical & experimental ophthalmology 2000;28(1):3-8.
2000: Thomas Gardner; David Antonetti; Alistair Barber; Kathryn F Lanoue; M Nakamura
New insights into the pathophysiology of diabetic retinopathy: potential cell-specific therapeutic targets.
Diabetes technology & therapeutics 2000;2(4):601-8.
1999: David Antonetti; E Lieth; Alistair Barber; Thomas Gardner
Molecular mechanisms of vascular permeability in diabetic retinopathy.
Seminars in ophthalmology 1999;14(4):240-8.
1999: David Antonetti; Alistair Barber; L A Hollinger; Ellen B Wolpert; Thomas Gardner
Vascular endothelial growth factor induces rapid phosphorylation of tight junction proteins occludin and zonula occluden 1. A potential mechanism for vascular permeability in diabetic retinopathy and tumors.
The Journal of biological chemistry 1999;274(33):23463-7.
1999: Thomas Gardner; David Antonetti; Alistair Barber; E Lieth; J A Tarbell
The molecular structure and function of the inner blood-retinal barrier. Penn State Retina Research Group.
Documenta ophthalmologica. Advances in ophthalmology 1999;97(3-4):229-37.
1998: David Antonetti; Alistair Barber; SA Khin; E Lieth; John M Tarbell; Thomas Gardner
Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: vascular endothelial growth factor decreases occludin in retinal endothelial cells. Penn State Retina Research Group.
Diabetes 1998;47(12):1953-9.
1998: Alistair Barber; E Lieth; SA Khin; David Antonetti; A G Buchanan; Thomas Gardner
Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin.
The Journal of clinical investigation 1998;102(4):783-91.
1998: E Lieth; Alistair Barber; B Xu; C Dice; MJ Ratz; Diana Tanase; J M Strother
Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy. Penn State Retina Research Group.
Diabetes 1998;47(5):815-20.
1997: Thomas Gardner; E Lieth; SA Khin; Alistair Barber; D J Bonsall; T Lesher; K Rice; W A Brennan
Astrocytes increase barrier properties and ZO-1 expression in retinal vascular endothelial cells.
Investigative ophthalmology & visual science 1997;38(11):2423-7.
1997: IA Paterson; Alistair Barber; DL Gelowitz; Chris Voll
(-)Deprenyl reduces delayed neuronal death of hippocampal pyramidal cells.
Neuroscience and biobehavioral reviews 1997;21(2):181-6.
1997: Alistair Barber; E Lieth
Agrin accumulates in the brain microvascular basal lamina during development of the blood-brain barrier.
Developmental dynamics : an official publication of the American Association of Anatomists 1997;208(1):62-74.
1996: Thomas Gardner; T Lesher; SA Khin; C Vu; Alistair Barber; W A Brennan
Histamine reduces ZO-1 tight-junction protein expression in cultured retinal microvascular endothelial cells.
The Biochemical journal 1996;320 ( Pt 3)():717-21.
1993: Alistair Barber; Peter H Yu; Alan A Boulton
Chronic effects of monoamine oxidase-B inhibitors on the behaviour of aged mice.
Life sciences 1993;53(9):739-47.
1991: Alistair Barber; Steven P R Rose
Amnesia induced by 2-deoxygalactose in the day-old chick: lateralization of effects in two different one-trial learning tasks.
Behavioral and neural biology 1991;56(1):77-88.