FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Ann Leen

Research Profile

Anatomy

Living Beings

Procedures

Chemicals & Drugs

Disorders

Physiology

Co-author Network

Publications

TOP 3
C Sanchez; P Bajgain; M K Brenner; R Chan; Ann Leen; M Mims; G Palapattu; S Rambally; C M Rooney; J F Vera
Combining T-cell immunotherapy and anti-androgen therapy for prostate cancer.
Ulrike Gerdemann; Stephen M Gottschalk; Helen E Heslop; Usha L Katari; Jacqueline M Keirnan; Alana Kennedy-Nasser; Laura Keukens; Malcolm K Brenner; Anne P de Pagter; Chinh T Q Nguyen; Carlos A Ramos; Cliona M Rooney; Ann Leen
Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation.
Carlos A Ramos; Barbara Savoldo; Erich M Sturgis; Gayatri M Vyas; Matthew L Anderson; Malcolm K Brenner; Ulrike Gerdemann; Helen E Heslop; Ann Leen; Neeharika Narala; Cliona M Rooney
Human papillomavirus type 16 E6/E7-specific cytotoxic T lymphocytes for adoptive immunotherapy of HPV-associated malignancies.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Ann Leen (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: C Sanchez; P Bajgain; M K Brenner; R Chan; Ann Leen; M Mims; G Palapattu; S Rambally; C M Rooney; J F Vera
Combining T-cell immunotherapy and anti-androgen therapy for prostate cancer.
Prostate cancer and prostatic diseases 2013;16(2):123-31.
2013: Ulrike Gerdemann; Stephen M Gottschalk; Helen E Heslop; Usha L Katari; Jacqueline M Keirnan; Alana Kennedy-Nasser; Laura Keukens; Malcolm K Brenner; Anne P de Pagter; Chinh T Q Nguyen; Carlos A Ramos; Cliona M Rooney; Ann Leen
Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation.
Blood 2013;121(1):207-18.
2013: Carlos A Ramos; Barbara Savoldo; Erich M Sturgis; Gayatri M Vyas; Matthew L Anderson; Malcolm K Brenner; Ulrike Gerdemann; Helen E Heslop; Ann Leen; Neeharika Narala; Cliona M Rooney
Human papillomavirus type 16 E6/E7-specific cytotoxic T lymphocytes for adoptive immunotherapy of HPV-associated malignancies.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2013;36(1):66-76.
2012: Ulrike Gerdemann; Stephen Gottschalk; Helen E Heslop; Leslie E Huye; Usha L Katari; Jacqueline M Keirnan; Malcolm K Brenner; Anne S Christin; Sravya Ennamuri; Serena K Perna; Cliona M Rooney; Ryu Yanagisawa; Ann Leen
Rapidly generated multivirus-specific cytotoxic T lymphocytes for the prophylaxis and treatment of viral infections.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(8):1622-32.
2012: Sari Pesonen; Saila K Pesonen; Tuuli Ranki; Tuomo Alanko; Vincenzo Cerullo; Iulia Diaconu; Ulrike Gerdemann; Elina Haavisto; Sirkka-Liisa Holm; Timo Joensuu; Kalevi Kairemo; Anna Kanerva; Lotta Kangasniemi; Aila Karioja-Kallio; Satu Kauppinen; Leena Laasonen; Ann Leen; Minna Oksanen; Kaarina P L Partanen; Akseli Hemminki
Oncolytic immunotherapy of advanced solid tumors with a CD40L-expressing replicating adenovirus: assessment of safety and immunologic responses in patients.
Cancer research 2012;72(7):1621-31.
2012: Alexia Ghazi; Stephen Gottschalk; Zakaria Grada; Robert Grossman; Patrick J Hanley; Meenakshi Hegde; Helen E Heslop; Yvonne Kew; Ann Leen; Suzanne Z Powell; Cliona M Rooney; Michael E Scheurer; Donald Shaffer; Aidin Ashoori; Catherine M Bollard; Vita S Brawley; Nabil Ahmed
Generation of polyclonal CMV-specific T cells for the adoptive immunotherapy of glioblastoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2012;35(2):159-68.
2011: Ulrike Gerdemann; Stephen Gottschalk; Helen E Heslop; Usha Katari; Catherine M Bollard; Malcolm K Brenner; Anne S Christin; Conrad R Cruz; Cliona M Rooney; Alexandra Rousseau; Barbara Savoldo; Tamara Tripic; Juan F Vera; Ann Leen
Cytotoxic T lymphocytes simultaneously targeting multiple tumor-associated antigens to treat EBV negative lymphoma.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(12):2258-68.
2011: Yozo Nakazawa; Lisa Rollins; Vita S Salsman; Matthew H Wilson; Nabil Ahmed; Gianpietro Dotti; Stephen Gottschalk; Leslie E Huye; Ann Leen; Cliona M Rooney
PiggyBac-mediated cancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(12):2133-43.
2011: Usha L Katari; Jacqueline M Keirnan; Ann Leen; William E Fisher; Sally E Hodges; Anna C Worth; Juan F Vera
Engineered T cells for pancreatic cancer treatment.
HPB : the official journal of the International Hepato Pancreato Biliary Association 2011;13(9):643-50.
2011: Concetta Quintarelli; Gianpietro Dotti; Sayyeda T Hasan; BIAGIO DE ANGELIS; Valentina Hoyos; Santa Errichiello; Martha P Mims; Luigia Luciano; Jessica Shafer; Ann Leen; Helen E Heslop; Cliona M Rooney; Fabrizio Pane; Malcolm K Brenner; Barbara Savoldo
High-avidity cytotoxic T lymphocytes specific for a new PRAME-derived peptide can target leukemic and leukemic-precursor cells.
Blood 2011;117(12):3353-62.
2011: Ulrike Gerdemann; Cliona M Rooney; Juan F Vera; Ann Leen
Generation of multivirus-specific T cells to prevent/treat viral infections after allogeneic hematopoietic stem cell transplant.
Journal of visualized experiments : JoVE 2011;(51):.
2010: Cristhian J Ildefonso; Lingkun Kong; Ann Leen; Samantha J Chai; Veronica Petrochelli; Murali Chintagumpala; Mary Y Hurwitz; Patricia Chévez-Barrios; Richard L Hurwitz
Absence of systemic immune response to adenovectors after intraocular administration to children with retinoblastoma.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(10):1885-90.
2010: Jessica A Shafer; Conrad R Cruz; Ann Leen; Stephanie Ku; An Lu; Alexandra Rousseau; Helen E Heslop; Cliona M Rooney; Catherine M Bollard; Aaron E Foster
Antigen-specific cytotoxic T lymphocytes can target chemoresistant side-population tumor cells in Hodgkin lymphoma.
Leukemia & lymphoma 2010;51(5):870-80.
2010: Juan F Vera; Lara J Brenner; Ulrike Gerdemann; Minhtran C Ngo; Uluhan Sili; Hao Liu; John Wilson; Gianpietro Dotti; Helen E Heslop; Ann Leen; Cliona M Rooney
Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex).
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010;33(3):305-15.
2009: Ann Leen; Anne Christin; G Douglas Myers; Hao Liu; Conrad R Cruz; Patrick J Hanley; Alana A Kennedy-Nasser; Kathryn S Leung; Adrian P Gee; Robert A Krance; Malcolm K Brenner; Helen E Heslop; Cliona M Rooney; Catherine M Bollard
Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation.
Blood 2009;114(19):4283-92.
2009: Ulrike Gerdemann; Anne S Christin; Juan F Vera; Carlos A Ramos; Yuriko Fujita; Hao Liu; Dagmar Dilloo; Helen E Heslop; Malcolm K Brenner; Cliona M Rooney; Ann Leen
Nucleofection of DCs to generate Multivirus-specific T cells for prevention or treatment of viral infections in the immunocompromised host.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(9):1616-25.
2009: Anjum S Kaka; Donald Shaffer; Ryan Hartmaier; Ryan Hartmeier; Ann Leen; An Lu; Adham Bear; Cliona M Rooney; Aaron E Foster
Genetic modification of T cells with IL-21 enhances antigen presentation and generation of central memory tumor-specific cytotoxic T-lymphocytes.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009;32(7):726-36.
2009: Patrick J Hanley; Conrad Russell Young Cruz; Barbara Savoldo; Ann Leen; Maja Stanojevic; Mariam Khalil; William Decker; Jeffrey J Molldrem; Hao Liu; Adrian P Gee; Cliona M Rooney; Helen E Heslop; Gianpietro Dotti; Malcolm K Brenner; Elizabeth J Shpall; Catherine M Bollard
Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes.
Blood 2009;114(9):1958-67.
2009: Juan F Vera; Valentina Hoyos; Barbara Savoldo; Concetta Quintarelli; Greta M P Giordano Attianese; Ann Leen; Hao Liu; Aaron E Foster; Helen E Heslop; Cliona M Rooney; Malcolm K Brenner; Gianpietro Dotti
Genetic manipulation of tumor-specific cytotoxic T lymphocytes to restore responsiveness to IL-7.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(5):880-8.
2008: Ann Leen; Helen E Heslop
Cytotoxic T lymphocytes as immune-therapy in haematological practice.
British journal of haematology 2008;143(2):169-79.
2008: Yuriko Fujita; Ann Leen; Jiali Sun; Yozo Nakazawa; Eric Yvon; Helen E Heslop; Malcolm K Brenner; Cliona M Rooney
Exploiting cytokine secretion to rapidly produce multivirus-specific T cells for adoptive immunotherapy.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(7):665-74.
2008: Anjum S Kaka; Aaron E Foster; Heidi L Weiss; Cliona M Rooney; Ann Leen
Using dendritic cell maturation and IL-12 producing capacity as markers of function: a cautionary tale.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(4):359-69.
2008: Ann Leen; Anne Christin; Mariam Khalil; Heidi Weiss; Adrian P Gee; Malcolm K Brenner; Helen E Heslop; Cliona M Rooney; Catherine M Bollard
Identification of hexon-specific CD4 and CD8 T-cell epitopes for vaccine and immunotherapy.
Journal of virology 2008;82(1):546-54.
2007: Catherine M Bollard; Stephen Gottschalk; Ann Leen; Heidi Weiss; Karin C Straathof; George Carrum; Mariam Khalil; Meng-fen Wu; M Helen Huls; Chung-Che Chang; Mary V Gresik; Adrian P Gee; Malcolm K Brenner; Cliona M Rooney; Helen E Heslop
Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer.
Blood 2007;110(8):2838-45.
2007: Aaron E Foster; Ann Leen; Timothy Lee; Takayuki Okamura; An Lu; Juan Vera; Rachel Atkinson; Catherine M Bollard; Gianpietro Dotti; Cliona M Rooney
Autologous designer antigen-presenting cells by gene modification of T lymphocyte blasts with IL-7 and IL-12.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007;30(5):506-16.
2007: G Douglas Myers; Catherine M Bollard; M-F Wu; Heidi Weiss; Cliona M Rooney; Helen E Heslop; Ann Leen
Reconstitution of adenovirus-specific cell-mediated immunity in pediatric patients after hematopoietic stem cell transplantation.
Bone marrow transplantation 2007;39(11):677-86.
2007: Ann Leen; Maheshika Ratnayake; Aaron Foster; Kenneth Heym; Nabil Ahmed; Cliona M Rooney; Stephen Gottschalk
Contact-activated monocytes: efficient antigen presenting cells for the stimulation of antigen-specific T cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007;30(1):96-107.
2007: Ann Leen; Cliona M Rooney; Aaron E Foster
Improving T cell therapy for cancer.
Annual review of immunology 2007;25():243-65.
2006: Ann Leen; G Douglas Myers; Uluhan Sili; M Helen Huls; Heidi Weiss; Kathryn S Leung; George Carrum; Robert A Krance; Chung-Che Chang; Jeffrey J Molldrem; Adrian P Gee; Malcolm K Brenner; Helen E Heslop; Cliona M Rooney; Catherine M Bollard
Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals.
Nature medicine 2006;12(10):1160-6.
2006: Ann Leen; Catherine M Bollard; G Douglas Myers; Cliona M Rooney
Adenoviral infections in hematopoietic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(3):243-51.
2005: Ann Leen; G Douglas Myers; Catherine M Bollard; M Helen Huls; Uluhan Sili; Adrian P Gee; Helen E Heslop; Cliona M Rooney
T-cell immunotherapy for adenoviral infections of stem-cell transplant recipients.
Annals of the New York Academy of Sciences 2005;1062():104-15.
2005: Karin C Straathof; Ann Leen; Elizabeth Buza; Graham Taylor; M Helen Huls; Helen E Heslop; Cliona M Rooney; Catherine M Bollard
Characterization of latent membrane protein 2 specificity in CTL lines from patients with EBV-positive nasopharyngeal carcinoma and lymphoma.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(6):4137-47.
2005: Heather M Long; Tracey A Haigh; Nancy H Gudgeon; Ann Leen; CW Tsang; J Brooks; Elise Landais; Elisabeth Houssaint; Steven P Lee; Alan B Rickinson; Graham S Taylor
CD4+ T-cell responses to Epstein-Barr virus (EBV) latent-cycle antigens and the recognition of EBV-transformed lymphoblastoid cell lines.
Journal of virology 2005;79(8):4896-907.
2005: Ann Leen; Cliona M Rooney
Adenovirus as an emerging pathogen in immunocompromised patients.
British journal of haematology 2005;128(2):135-44.
2004: Ann Leen; Uluhan Sili; Elio F Vanin; Alan M Jewell; WeiDong Xie; Dario Vignali; Pedro Piedra; Malcolm K Brenner; Cliona M Rooney
Conserved CTL epitopes on the adenovirus hexon protein expand subgroup cross-reactive and subgroup-specific CD8+ T cells.
Blood 2004;104(8):2432-40.
2004: Catherine M Bollard; Karin C Straathof; M Helen Huls; Ann Leen; Kristine Lacuesta; Alan Davis; Stephen Gottschalk; Malcolm K Brenner; Helen E Heslop; Cliona M Rooney
The generation and characterization of LMP2-specific CTLs for use as adoptive transfer from patients with relapsed EBV-positive Hodgkin disease.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2004;27(4):317-27.
2004: Catherine M Bollard; Ingrid Kuehnle; Ann Leen; Cliona M Rooney; Helen E Heslop
Adoptive immunotherapy for posttransplantation viral infections.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2004;10(3):143-55.
2004: Ann Leen; Uluhan Sili; Barbara Savoldo; Alan M Jewell; Pedro Piedra; Malcolm K Brenner; Cliona M Rooney
Fiber-modified adenoviruses generate subgroup cross-reactive, adenovirus-specific cytotoxic T lymphocytes for therapeutic applications.
Blood 2004;103(3):1011-9.
2002: Pauline Meij; Ann Leen; Alan B Rickinson; Saertje Verkoeijen; Marcel B H J Vervoort; Elisabeth Bloemena; Jaap Middeldorp
Identification and prevalence of CD8(+) T-cell responses directed against Epstein-Barr virus-encoded latent membrane protein 1 and latent membrane protein 2.
International journal of cancer. Journal international du cancer 2002;99(1):93-9.
2001: Ann Leen; Pauline Meij; IV Redchenko; Jaap Middeldorp; Elisabeth Bloemena; Alan B Rickinson; Neil Blake
Differential immunogenicity of Epstein-Barr virus latent-cycle proteins for human CD4(+) T-helper 1 responses.
Journal of virology 2001;75(18):8649-59.