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Roger Johns

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Chunling Fan; Brian A Johns; Irina Kolosova; QINGNING SU; Roger Johns
Choosing the right antibody for resistin-like molecule (RELM/FIZZ) family members.
Yun Wang; Anshi Wu; Jie Xu; Zhijun Chen; Roger Johns; Rong Shi; Yue Wang; Yujie Zhao; Yun Yue
Epigenetics as a new therapeutic target for postoperative cognitive dysfunction.
Irina Kolosova; John Skinner; Daniel Angelini; Chris Cheadle; Chunling Fan; Roger Johns
Resistin-like molecule α stimulates proliferation of mesenchymal stem cells while maintaining their multipotency.

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2013: Chunling Fan; Brian A Johns; Irina Kolosova; QINGNING SU; Roger Johns
Choosing the right antibody for resistin-like molecule (RELM/FIZZ) family members.
Histochemistry and cell biology 2013;139(4):605-13.
2013: Yun Wang; Anshi Wu; Jie Xu; Zhijun Chen; Roger Johns; Rong Shi; Yue Wang; Yujie Zhao; Yun Yue
Epigenetics as a new therapeutic target for postoperative cognitive dysfunction.
Medical hypotheses 2013;80(3):249-51.
2013: Irina Kolosova; John Skinner; Daniel Angelini; Chris Cheadle; Chunling Fan; Roger Johns
Resistin-like molecule α stimulates proliferation of mesenchymal stem cells while maintaining their multipotency.
Stem cells and development 2013;22(2):239-47.
2013: Daniel Angelini; Chris Cheadle; Hazim El-Haddad; Chunling Fan; Andre Poloczek; John T Skinner; QINGNING SU; Kazuyo Yamaji-Kegan; Roger Johns
Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) in chronic hypoxia- and antigen-mediated pulmonary vascular remodeling.
Respiratory research 2013;14():1.
2013: Feng Tao; Haiying Wu; Ya Yang; Visar Belegu; Orion Furmanski; Andres Hurtado; Qun Li; Su Liu; JOHN MCDONALD; John Skinner; Roger Johns
Role of neuregulin-1/ErbB signaling in stem cell therapy for spinal cord injury-induced chronic neuropathic pain.
Stem cells (Dayton, Ohio) 2013;31(1):83-91.
2012: Shari Bolen; Hsien-Yen Chang; Suzanne M Goodwin; Roger Johns; Thomas H Magnuson; Thomas M Richards; Andrew D Shore; Jonathan P Weiner; Jeanne M Clark
Clinical outcomes after bariatric surgery: a five-year matched cohort analysis in seven US states.
Obesity surgery 2012;22(5):749-63.
2012: Chris Cheadle; JINSHUI FAN; Reda E Girgis; Dmitry N Grigoryev; Sangjucta Barkataki; Kathleen C Barnes; Alan E Berger; Meher Boorgula; Laura K Hummers; Roger Johns; Stephen C Mathai; A MICHAEL MCDEVITT; Yumiko Sugawara; Tonya N Watkins; Fredrick M Wigley; Ari L Zaiman; Paul M Hassoun
Erythroid-specific transcriptional changes in PBMCs from pulmonary hypertension patients.
PloS one 2012;7(4):e34951.
2011: Catherine L Chen; Jeanne M Clark; Roger Johns; MICHELE MANAHAN; Andrew D Shore; Martin A Makary
The impact of obesity on breast surgery complications.
Plastic and reconstructive surgery 2011;128(5):395e-402e.
2011: Chunling Fan; Zongming Fu; QINGNING SU; Daniel Angelini; Jennifer E Van Eyk; Roger Johns
S100A11 mediates hypoxia-induced mitogenic factor (HIMF)-induced smooth muscle cell migration, vesicular exocytosis, and nuclear activation.
Molecular & cellular proteomics : MCP 2011;10(3):M110.000901.
2010: Kazuyo Yamaji-Kegan; QINGNING SU; Daniel Angelini; Allen C Myers; Chris Cheadle; Roger Johns
Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) increases lung inflammation and activates pulmonary microvascular endothelial cells via an IL-4-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(9):5539-48.
2010: Feng Tao; John Skinner; Ya Yang; Roger Johns
Effect of PSD-95/SAP90 and/or PSD-93/chapsyn-110 deficiency on the minimum alveolar anesthetic concentration of halothane in mice.
Anesthesiology 2010;112(6):1444-51.
2010: Roger Johns
Th2 inflammation, hypoxia-induced mitogenic factor/FIZZ1, and pulmonary hypertension and vascular remodeling in schistosomiasis.
American journal of respiratory and critical care medicine 2010;181(3):203-5.
2010: Michelle Jo Semins; Andrew D Shore; Martin A Makary; Thomas H Magnuson; Roger Johns; Brian R Matlaga
The association of increasing body mass index and kidney stone disease.
The Journal of urology 2010;183(2):571-5.
2010: Daniel Angelini; QINGNING SU; Irina Kolosova; Chunling Fan; John T Skinner; Kazuyo Yamaji-Kegan; Michael I Collector; Saul J Sharkis; Roger Johns
Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELM alpha) recruits bone marrow-derived cells to the murine pulmonary vasculature.
PloS one 2010;5(6):e11251.
2009: Roger Johns; Kazuyo Yamaji-Kegan
Unveiling cell phenotypes in lung vascular remodeling.
American journal of physiology. Lung cellular and molecular physiology 2009;297(6):L1056-8.
2009: Daniel Angelini; QINGNING SU; Kazuyo Yamaji-Kegan; Chunling Fan; Xingwu Teng; Paul M Hassoun; Stephen C Yang; Hunter C Champion; Rubin M Tuder; Roger Johns
Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension.
American journal of respiratory cell and molecular biology 2009;41(5):553-61.
2009: Michelle J Semins; Brian R Matlaga; Andrew D Shore; Kimberley E Steele; Thomas H Magnuson; Roger Johns; Martin A Makary
The effect of gastric banding on kidney stone disease.
Urology 2009;74(4):746-9.
2009: Chunling Fan; QINGNING SU; Yun Li; Lihua Liang; Daniel Angelini; William B Guggino; Roger Johns
Hypoxia-induced mitogenic factor/FIZZ1 induces intracellular calcium release through the PLC-IP(3) pathway.
American journal of physiology. Lung cellular and molecular physiology 2009;297(2):L263-70.
2009: Brian R Matlaga; Andrew D Shore; Thomas H Magnuson; Jeanne M Clark; Roger Johns; Martin A Makary
Effect of gastric bypass surgery on kidney stone disease.
The Journal of urology 2009;181(6):2573-7.
2009: Kazuyo Yamaji-Kegan; QINGNING SU; Daniel Angelini; Roger Johns
IL-4 is proangiogenic in the lung under hypoxic conditions.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(9):5469-76.
2009: Daniel Angelini; QINGNING SU; Kazuyo Yamaji-Kegan; Chunling Fan; John T Skinner; Hunter C Champion; Michael T Crow; Roger Johns
Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) induces the vascular and hemodynamic changes of pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology 2009;296(4):L582-93.
2008: Feng Tao; QINGNING SU; Roger Johns
Cell-permeable peptide Tat-PSD-95 PDZ2 inhibits chronic inflammatory pain behaviors in mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(11):1776-82.
2008: Peizhong Mao; YUANXIANG TAO; MASAHIRO FUKAYA; Feng Tao; Dechun Li; Masahiko Watanabe; Roger Johns
Cloning and characterization of E-dlg, a novel splice variant of mouse homologue of the Drosophila discs large tumor suppressor binds preferentially to SAP102.
IUBMB life 2008;60(10):684-92.
2008: Y Sato; YUANXIANG TAO; QINGNING SU; Roger Johns
Post-synaptic density-93 mediates tyrosine-phosphorylation of the N-methyl-D-aspartate receptors.
Neuroscience 2008;153(3):700-8.
2008: Feng Tao; Roger Johns
Effect of disrupting N-methyl-d-aspartate receptor-postsynaptic density protein-95 interactions on the threshold for halothane anesthesia in mice.
Anesthesiology 2008;108(5):882-7.
2008: Wen-Jinn Liaw; Xu-Guang Zhu; Myron Yaster; Roger Johns; Estelle B Gauda; YUANXIANG TAO
Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein.
Molecular pain 2008;4():45.
2007: Reda E Girgis; Shehzin Mozammel; Hunter C Champion; Dechun Li; Xinqi Peng; Larissa A Shimoda; Rubin M Tuder; Roger Johns; Paul M Hassoun
Regression of chronic hypoxic pulmonary hypertension by simvastatin.
American journal of physiology. Lung cellular and molecular physiology 2007;292(5):L1105-10.
2007: QINGNING SU; Yifu Zhou; Roger Johns
Bruton's tyrosine kinase (BTK) is a binding partner for hypoxia induced mitogenic factor (HIMF/FIZZ1) and mediates myeloid cell chemotaxis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(7):1376-82.
2007: Dmitry N Grigoryev; Shwu-Fan Ma; Larissa A Shimoda; Roger Johns; Byungkook Lee; Joe G. N. Garcia
Exon-based mapping of microarray probes: recovering differential gene expression signal in underpowered hypoxia experiment.
Molecular and cellular probes 2007;21(2):134-9.
2006: Kazuyo Yamaji-Kegan; QINGNING SU; Daniel Angelini; Hunter C Champion; Roger Johns
Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2.
American journal of physiology. Lung cellular and molecular physiology 2006;291(6):L1159-68.
2006: Feng Tao; John Skinner; QINGNING SU; Roger Johns
New role for spinal Stargazin in alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated pain sensitization after inflammation.
Journal of neuroscience research 2006;84(4):867-73.
2006: YUANXIANG TAO; Roger Johns
PDZ domains at excitatory synapses: potential molecular targets for persistent pain treatment.
Current neuropharmacology 2006;4(3):217-23.
2006: Gerard F Anderson; Bianca K Frogner; Roger Johns; Uwe E Reinhardt
Health care spending and use of information technology in OECD countries.
Health affairs (Project Hope) 2006;25(3):819-31.
2005: Ya-Chun Chu; Yun Guan; John Skinner; Srinivasa N Raja; Roger Johns; YUANXIANG TAO
Effect of genetic knockout or pharmacologic inhibition of neuronal nitric oxide synthase on complete Freund's adjuvant-induced persistent pain.
Pain 2005;119(1-3):113-23.
2005: Reda E Girgis; Shwu-Fan Ma; S Ye; Dmitry N Grigoryev; Dechun Li; Paul M Hassoun; Rubin M Tuder; Roger Johns; Joe G. N. Garcia
Differential gene expression in chronic hypoxic pulmonary hypertension: effect of simvastatin treatment.
Chest 2005;128(6 Suppl):579S.
2005: Reda E Girgis; Hunter C Champion; Gregory B Diette; Roger Johns; Solbert Permutt; JIM SYLVESTER
Decreased exhaled nitric oxide in pulmonary arterial hypertension: response to bosentan therapy.
American journal of respiratory and critical care medicine 2005;172(3):352-7.
2005: Wen-Jinn Liaw; Robert L Stephens; Brian C Binns; Yachun Chu; Jehuda P Sepkuty; Roger Johns; Jeffrey rothstein; YUANXIANG TAO
Spinal glutamate uptake is critical for maintaining normal sensory transmission in rat spinal cord.
Pain 2005;115(1-2):60-70.
2004: Yun Xu; Bosheng Zhang; Zichun Hua; Roger Johns; David S Bredt; YUANXIANG TAO
Targeted disruption of PSD-93 gene reduces platelet-activating factor-induced neurotoxicity in cultured cortical neurons.
Experimental neurology 2004;189(1):16-24.
2004: Klaus F Wagner; Ann-Katrin Hellberg; Susan Balenger; Reinhard Depping; Jeffrey M Dodd-o; Roger Johns; Dechun Li
Hypoxia-induced mitogenic factor has antiapoptotic action and is upregulated in the developing lung: coexpression with hypoxia-inducible factor-2alpha.
American journal of respiratory cell and molecular biology 2004;31(3):276-82.
2004: YUANXIANG TAO; Roger Johns
Neuronal PDZ domains: a promising new molecular target for inhaled anesthetics?
Molecular interventions 2004;4(4):215-21.
2004: William H Stotz; Dechun Li; Roger Johns
Exogenous nitric oxide upregulates p21(waf1/cip1) in pulmonary microvascular smooth muscle cells.
Journal of vascular research 2004;41(3):211-9.
2004: Feng Tao; YUANXIANG TAO; Chengshui Zhao; Sylvain Dore; Wen-Jinn Liaw; Srinivasa N Raja; Roger Johns
Differential roles of neuronal and endothelial nitric oxide synthases during carrageenan-induced inflammatory hyperalgesia.
Neuroscience 2004;128(2):421-30.
2004: Feng Tao; Wen-Jinn Liaw; B Zhang; Myron Yaster; Jeffrey rothstein; Roger Johns; YUANXIANG TAO
Evidence of neuronal excitatory amino acid carrier 1 expression in rat dorsal root ganglion neurons and their central terminals.
Neuroscience 2004;123(4):1045-51.
2004: Wen-Jinn Liaw; B Zhang; Feng Tao; Myron Yaster; Roger Johns; YUANXIANG TAO
Knockdown of spinal cord postsynaptic density protein-95 prevents the development of morphine tolerance in rats.
Neuroscience 2004;123(1):11-5.
2003: Bosheng Zhang; Feng Tao; Wen-Jinn Liaw; David S Bredt; Roger Johns; YUANXIANG TAO
Effect of knock down of spinal cord PSD-93/chapsin-110 on persistent pain induced by complete Freund's adjuvant and peripheral nerve injury.
Pain 2003;106(1-2):187-96.
2003: Lesley J Millatt; Guy St J Whitley; Dechun Li; James M Leiper; Helmy M Siragy; Robert M Carey; Roger Johns
Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension.
Circulation 2003;108(12):1493-8.
2003: Ming Fang; YUANXIANG TAO; Fahu He; Mingjie Zhang; Claire F Levine; Peizhong Mao; Feng Tao; Chih-Ling Chou; Scheherazade Sadegh-Nasseri; Roger Johns
Synaptic PDZ domain-mediated protein interactions are disrupted by inhalational anesthetics.
The Journal of biological chemistry 2003;278(38):36669-75.
2003: Reda E Girgis; Dechun Li; Xinhua Zhan; Joe G. N. Garcia; Rubin M Tuder; Paul M Hassoun; Roger Johns
Attenuation of chronic hypoxic pulmonary hypertension by simvastatin.
American journal of physiology. Heart and circulatory physiology 2003;285(3):H938-45.
2003: YUANXIANG TAO; Gavin Rumbaugh; Guo-Du Wang; Ronald S Petralia; Chengshui Zhao; Frederick W Kauer; Feng Tao; Min Zhuo; Robert Wenthold; Srinivasa N Raja; Richard Huganir; David S Bredt; Roger Johns
Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(17):6703-12.
2003: Xingwu Teng; Dechun Li; Hunter C Champion; Roger Johns
FIZZ1/RELMalpha, a novel hypoxia-induced mitogenic factor in lung with vasoconstrictive and angiogenic properties.
Circulation research 2003;92(10):1065-7.
2003: Feng Tao; YUANXIANG TAO; Peizhong Mao; Chengshui Zhao; D Li; Wen-Jinn Liaw; Srinivasa N Raja; Roger Johns
Intact carrageenan-induced thermal hyperalgesia in mice lacking inducible nitric oxide synthase.
Neuroscience 2003;120(3):847-54.
2003: Feng Tao; YUANXIANG TAO; Peizhong Mao; Roger Johns
Role of postsynaptic density protein-95 in the maintenance of peripheral nerve injury-induced neuropathic pain in rats.
Neuroscience 2003;117(3):731-9.
2003: Xinhua Zhan; Dechun Li; Roger Johns
Expression of endothelial nitric oxide synthase in ciliated epithelia of rats.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003;51(1):81-7.
2002: Xingwu Teng; Dechuan Li; Roger Johns
Hypoxia up-regulates mouse vascular endothelial growth factor D promoter activity in rat pulmonary microvascular smooth-muscle cells.
Chest 2002;121(3 Suppl):82S-83S.
2002: Dechun Li; Xingwu Teng; Roger Johns
Up-regulation of angiogenic factor expression in hypoxia-treated mouse lung demonstrated by DNA array technique.
Chest 2002;121(3 Suppl):78S.
2002: Xingwu Teng; Dechun Li; John D Catravas; Roger Johns
C/EBP-beta mediates iNOS induction by hypoxia in rat pulmonary microvascular smooth muscle cells.
Circulation research 2002;90(2):125-7.
2002: YUANXIANG TAO; Roger Johns
Activation and up-regulation of spinal cord nitric oxide receptor, soluble guanylate cyclase, after formalin injection into the rat hind paw.
Neuroscience 2002;112(2):439-46.
2001: Feng Tao; YUANXIANG TAO; J A Gonzalez; Ming Fang; Peizhong Mao; Roger Johns
Knockdown of PSD-95/SAP90 delays the development of neuropathic pain in rats.
Neuroreport 2001;12(15):3251-5.
2001: F Jung; U Weiland; Roger Johns; Christian Ihling; Stefanie Dimmeler
Chronic hypoxia induces apoptosis in cardiac myocytes: a possible role for Bcl-2-like proteins.
Biochemical and biophysical research communications 2001;286(2):419-25.
2001: Dechun Li; Victor E Laubach; Roger Johns
Upregulation of lung soluble guanylate cyclase during chronic hypoxia is prevented by deletion of eNOS.
American journal of physiology. Lung cellular and molecular physiology 2001;281(2):L369-76.
2001: Roger Johns
New mechanisms for inhaled NO: release of an endogenous NO inhibitor?
Anesthesiology 2001;95(1):3-5.
2001: YUANXIANG TAO; Roger Johns
Effect of the deficiency of spinal PSD-95/SAP90 on the minimum alveolar anesthetic concentration of isoflurane in rats.
Anesthesiology 2001;94(6):1010-5.
2001: Shyamal Premaratne; C Xue; John M McCarty; M Zaki; Robert W McCuen; Roger Johns; Wolfgang Schepp; Bruno Neu; R Lippman; Pamela Melone; Mitchell L Schubert
Neuronal nitric oxide synthase: expression in rat parietal cells.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(2):G308-13.
2000: Lisa A Palmer; Benjamin Gaston; Roger Johns
Normoxic stabilization of hypoxia-inducible factor-1 expression and activity: redox-dependent effect of nitrogen oxides.
Molecular pharmacology 2000;58(6):1197-203.
2000: K Fang; Roger Johns; Timothy Macdonald; Michael Kinter; Benjamin Gaston
S-nitrosoglutathione breakdown prevents airway smooth muscle relaxation in the guinea pig.
American journal of physiology. Lung cellular and molecular physiology 2000;279(4):L716-21.
2000: T R Quinlan; D Li; Victor E Laubach; Edward Shesely; N Zhou; Roger Johns
eNOS-deficient mice show reduced pulmonary vascular proliferation and remodeling to chronic hypoxia.
American journal of physiology. Lung cellular and molecular physiology 2000;279(4):L641-50.
2000: YUANXIANG TAO; Y Q Li; Z Q Zhao; Roger Johns
Synaptic relationship of the neurons containing a metabotropic glutamate receptor, MGluR5, with nociceptive primary afferent and GABAergic terminals in rat spinal superficial laminae.
Brain research 2000;875(1-2):138-43.
2000: Dechun Li; G Shirakami; Xi Zhan; Roger Johns
Regulation of ciliary beat frequency by the nitric oxide-cyclic guanosine monophosphate signaling pathway in rat airway epithelial cells.
American journal of respiratory cell and molecular biology 2000;23(2):175-81.
2000: G Shirakami; Dechun Li; Xi Zhan; Roger Johns
Propofol stimulates ciliary motility via the nitric oxide-cyclic GMP pathway in cultured rat tracheal epithelial cells.
Anesthesiology 2000;93(2):482-8.
2000: E Haddad; Stuart M Lowson; Roger Johns; George F Rich
Use of inhaled nitric oxide perioperatively and in intensive care patients.
Anesthesiology 2000;92(6):1821-5.
2000: YUANXIANG TAO; Roger Johns
Activation of cGMP-dependent protein kinase Ialpha is required for N-methyl-D-aspartate- or nitric oxide-produced spinal thermal hyperalgesia.
European journal of pharmacology 2000;392(3):141-5.
2000: F Jung; Lisa A Palmer; N Zhou; Roger Johns
Hypoxic regulation of inducible nitric oxide synthase via hypoxia inducible factor-1 in cardiac myocytes.
Circulation research 2000;86(3):319-25.
2000: YUANXIANG TAO; A Hassan; Roger Johns
Intrathecally administered cGMP-dependent protein kinase Ialpha inhibitor significantly reduced the threshold for isoflurane anesthesia: implication for a novel role of cGMP-dependent protein kinase Ialpha.
Anesthesiology 2000;92(2):493-9.
2000: YUANXIANG TAO; Y Z Huang; Lin Mei; Roger Johns
Expression of PSD-95/SAP90 is critical for N-methyl-D-aspartate receptor-mediated thermal hyperalgesia in the spinal cord.
Neuroscience 2000;98(2):201-6.
2000: YUANXIANG TAO; A Hassan; E Haddad; Roger Johns
Expression and action of cyclic GMP-dependent protein kinase Ialpha in inflammatory hyperalgesia in rat spinal cord.
Neuroscience 2000;95(2):525-33.
1999: X Zhan; D Li; Roger Johns
Immunohistochemical evidence for the NO cGMP signaling pathway in respiratory ciliated epithelia of rat.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1999;47(11):1369-74.
1999: D Li; N Zhou; Roger Johns
Soluble guanylate cyclase gene expression and localization in rat lung after exposure to hypoxia.
The American journal of physiology 1999;277(4 Pt 1):L841-7.
1999: E Haddad; Roger Johns; Thomas N Pajewski
Sevoflurane MAC and cerebellar cyclic GMP.
Anesthesiology 1999;90(5):1487-8.
1999: Zhiyi Zuo; A Tichotsky; Roger Johns
Inhibition of excitatory neurotransmitter-nitric oxide signaling pathway by inhalational anesthetics.
Neuroscience 1999;93(3):1167-72.
1999: ZQ Wang; Lesley J Millatt; N T Heiderstadt; Helmy M Siragy; Roger Johns; Robert M Carey
Differential regulation of renal angiotensin subtype AT1A and AT2 receptor protein in rats with angiotensin-dependent hypertension.
Hypertension 1999;33(1):96-101.
1998: DU Frank; Damian J Horstman; G N Morris; Roger Johns; George F Rich
Regulation of the endogenous NO pathway by prolonged inhaled NO in rats.
Journal of applied physiology (Bethesda, Md. : 1985) 1998;85(3):1070-8.
1998: T R Quinlan; Victor E Laubach; N Zhou; Roger Johns
Alterations in nitric oxide synthase isoform expression in NOS knockout mice exposed to normoxia or hypoxia.
Chest 1998;114(1 Suppl):53S-55S.
1998: Timothy D Le Cras; RC Tyler; MP Horan; Kenneth G Morris; I F McMurty; Roger Johns; Steven H Abman
Effects of chronic hypoxia and altered hemodynamics on endothelial nitric oxide synthase and preproendothelin-1 expression in the adult rat lung.
Chest 1998;114(1 Suppl):35S-36S.
1998: Lisa A Palmer; Roger Johns
Hypoxia upregulates inducible (Type II) nitric oxide synthase in an HIF-1 dependent manner in rat pulmonary microvascular but not aortic smooth muscle cells.
Chest 1998;114(1 Suppl):33S-34S.
1998: Allen Everett; Timothy D Le Cras; C Xue; Roger Johns
eNOS expression is not altered in pulmonary vascular remodeling due to increased pulmonary blood flow.
The American journal of physiology 1998;274(6 Pt 1):L1058-65.
1998: Timothy D Le Cras; RC Tyler; MP Horan; Kenneth G Morris; Rubin M Tuder; Ivan F McMurtry; Roger Johns; Steven H Abman
Effects of chronic hypoxia and altered hemodynamics on endothelial nitric oxide synthase expression in the adult rat lung.
The Journal of clinical investigation 1998;101(4):795-801.
1998: Lisa A Palmer; Gregg L Semenza; M H Stoler; Roger Johns
Hypoxia induces type II NOS gene expression in pulmonary artery endothelial cells via HIF-1.
The American journal of physiology 1998;274(2 Pt 1):L212-9.
1998: C Xue; F Heller; Roger Johns; Allen Everett
Developmental expression and localization of the catalytic subunit of protein phosphatase 2A in rat lung.
Developmental dynamics : an official publication of the American Association of Anatomists 1998;211(1):1-10.
1997: Zhiyi Zuo; Roger Johns
Inhalational anesthetics up-regulate constitutive and lipopolysaccharide-induced inducible nitric oxide synthase expression and activity.
Molecular pharmacology 1997;52(4):606-12.
1997: A Rengasamy; Thomas N Pajewski; Roger Johns
Inhalational anesthetic effects on rat cerebellar nitric oxide and cyclic guanosine monophosphate production.
Anesthesiology 1997;86(3):689-98.
1996: Thomas N Pajewski; N Miao; Carl Lynch; Roger Johns
Volatile anesthetics affect calcium mobilization in bovine endothelial cells.
Anesthesiology 1996;85(5):1147-56.
1996: Thomas N Pajewski; CA DiFazio; J C Moscicki; Roger Johns
Nitric oxide synthase inhibitors, 7-nitro indazole and nitroG-L-arginine methyl ester, dose dependently reduce the threshold for isoflurane anesthesia.
Anesthesiology 1996;85(5):1111-9.
1996: C Xue; Roger Johns
Upregulation of nitric oxide synthase correlates temporally with onset of pulmonary vascular remodeling in the hypoxic rat.
Hypertension 1996;28(5):743-53.
1996: Zhiyi Zuo; J De Vente; Roger Johns
Halothane and isoflurane dose-dependently inhibit the cyclic GMP increase caused by N-methyl-D-aspartate in rat cerebellum: novel localization and quantitation by in vitro autoradiography.
Neuroscience 1996;74(4):1069-75.
1996: Roger Johns
Nitric oxide, cyclic guanosine monophosphate, and the anesthetic state.
Anesthesiology 1996;85(3):457-9.
1996: C Xue; S J Botkin; Roger Johns
Localization of endothelial NOS at the basal microtubule membrane in ciliated epithelium of rat lung.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1996;44(5):463-71.
1996: Zhiyi Zuo; A Tichotsky; Roger Johns
Halothane and isoflurane inhibit vasodilation due to constitutive but not inducible nitric oxide synthase. Implications for the site of anesthetic inhibition of the nitric oxide/guanylyl cyclase signaling pathway.
Anesthesiology 1996;84(5):1156-65.
1996: N P Lewis; Philip S Tsao; P R Rickenbacher; C Xue; Roger Johns; G A Haywood; Heiko E von der Leyen; P T Trindade; john cooke; Sharon A Hunt; Margaret E Billingham; Hannah A Valantine; Michael B Fowler
Induction of nitric oxide synthase in the human cardiac allograft is associated with contractile dysfunction of the left ventricle.
Circulation 1996;93(4):720-9.
1996: C M Roos; DU Frank; C Xue; Roger Johns; George F Rich
Chronic inhaled nitric oxide: effects on pulmonary vascular endothelial function and pathology in rats.
Journal of applied physiology (Bethesda, Md. : 1985) 1996;80(1):252-60.
1996: Timothy D Le Cras; C Xue; A Rengasamy; Roger Johns
Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung.
The American journal of physiology 1996;270(1 Pt 1):L164-70.
1996: C Xue; P R Reynolds; Roger Johns
Developmental expression of NOS isoforms in fetal rat lung: implications for transitional circulation and pulmonary angiogenesis.
The American journal of physiology 1996;270(1 Pt 1):L88-100.
1996: A Rengasamy; Roger Johns
Determination of Km for oxygen of nitric oxide synthase isoforms.
The Journal of pharmacology and experimental therapeutics 1996;276(1):30-3.
1995: C Xue; Roger Johns
Endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension.
The New England journal of medicine 1995;333(24):1642-4.
1995: L V Ravichandran; Roger Johns
Up-regulation of endothelial nitric oxide synthase expression by cyclic guanosine 3',5'-monophosphate.
FEBS letters 1995;374(2):295-8.
1995: Roger Johns; A Tichotsky; M Muro; J P Spaeth; Timothy D Le Cras; A Rengasamy
Halothane and isoflurane inhibit endothelium-derived relaxing factor-dependent cyclic guanosine monophosphate accumulation in endothelial cell-vascular smooth muscle co-cultures independent of an effect on guanylyl cyclase activation.
Anesthesiology 1995;83(4):823-34.
1995: Zhiyi Zuo; Roger Johns
Halothane, enflurane, and isoflurane do not affect the basal or agonist-stimulated activity of partially isolated soluble and particulate guanylyl cyclases of rat brain.
Anesthesiology 1995;83(2):395-404.
1995: Roger Johns
Nitric oxide and minimum alveolar concentration. TKO or knockout?
Anesthesiology 1995;83(1):6-7.
1995: L V Ravichandran; Roger Johns; A Rengasamy
Direct and reversible inhibition of endothelial nitric oxide synthase by nitric oxide.
The American journal of physiology 1995;268(6 Pt 2):H2216-23.
1995: A Rengasamy; L V Ravichandran; C G Reikersdorfer; Roger Johns
Inhalational anesthetics do not alter nitric oxide synthase activity.
The Journal of pharmacology and experimental therapeutics 1995;273(2):599-604.
1994: A Rengasamy; C Xue; Roger Johns
Immunohistochemical demonstration of a paracrine role of nitric oxide in bronchial function.
The American journal of physiology 1994;267(6 Pt 1):L704-11.
1994: C Xue; A Rengasamy; Timothy D Le Cras; P A Koberna; G C Dailey; Roger Johns
Distribution of NOS in normoxic vs. hypoxic rat lung: upregulation of NOS by chronic hypoxia.
The American journal of physiology 1994;267(6 Pt 1):L667-78.
1994: R G Merin; Roger Johns
Does isoflurane produce coronary vasoconstriction?
Anesthesiology 1994;81(5):1093-6.
1994: A Rengasamy; Roger Johns
Effect of hydrogen peroxide and catalase on rat cerebellum nitric oxide synthase.
Biochemical pharmacology 1994;48(2):423-5.
1994: Ross Tracey; C Xue; V Klinghofer; J Barlow; Jennifer Pollock; Ulrich Förstermann; Roger Johns
Immunochemical detection of inducible NO synthase in human lung.
The American journal of physiology 1994;266(6 Pt 1):L722-7.
1994: S G Pollock; J M Dent; C L Simek; Lawrence W Gimple; Roger Johns; Sanjiv Kaul; William D Spotnitz
Starr-Edwards valve thrombosis detected preoperatively by transesophageal echocardiography.
Catheterization and cardiovascular diagnosis 1994;31(2):156-7.
1994: George F Rich; Stuart M Lowson; Roger Johns; M O Daugherty; D R Uncles
Inhaled nitric oxide selectively decreases pulmonary vascular resistance without impairing oxygenation during one-lung ventilation in patients undergoing cardiac surgery.
Anesthesiology 1994;80(1):57-62; discussion 27A.
1993: Roger Johns
Endothelium, anesthetics, and vascular control.
Anesthesiology 1993;79(6):1381-91.
1993: A Rengasamy; Roger Johns
Inhibition of nitric oxide synthase by a superoxide generating system.
The Journal of pharmacology and experimental therapeutics 1993;267(3):1024-7.
1993: P Zelenkov; T McLoughlin; Roger Johns
Endotoxin enhances hypoxic constriction of rat aorta and pulmonary artery through induction of EDRF/NO synthase.
The American journal of physiology 1993;265(4 Pt 1):L346-54.
1993: George F Rich; C M Roos; S M Anderson; D C Urich; M O Daugherty; Roger Johns
Inhaled nitric oxide: dose response and the effects of blood in the isolated rat lung.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;75(3):1278-84.
1993: A Rengasamy; Roger Johns
Regulation of nitric oxide synthase by nitric oxide.
Molecular pharmacology 1993;44(1):124-8.
1993: George F Rich; G D Murphy; C M Roos; Roger Johns
Inhaled nitric oxide. Selective pulmonary vasodilation in cardiac surgical patients.
Anesthesiology 1993;78(6):1028-35.
1992: W K Park; Carl Lynch; Roger Johns
Effects of propofol and thiopental in isolated rat aorta and pulmonary artery.
Anesthesiology 1992;77(5):956-63.
1992: Roger Johns; J C Moscicki; CA DiFazio
Nitric oxide synthase inhibitor dose-dependently and reversibly reduces the threshold for halothane anesthesia. A role for nitric oxide in mediating consciousness?
Anesthesiology 1992;77(4):779-84.
1992: J K Brendel; Roger Johns
Isoflurane does not vasodilate rat thoracic aortic rings by endothelium-derived relaxing factor or other cyclic GMP-mediated mechanisms.
Anesthesiology 1992;77(1):126-31.
1992: M J Uggeri; G J Proctor; Roger Johns
Halothane, enflurane, and isoflurane attenuate both receptor- and non-receptor-mediated EDRF production in rat thoracic aorta.
Anesthesiology 1992;76(6):1012-7.
1992: Helmy M Siragy; Roger Johns; M J Peach; Robert M Carey
Nitric oxide alters renal function and guanosine 3',5'-cyclic monophosphate.
Hypertension 1992;19(6 Pt 2):775-9.
1991: Roger Johns
EDRF/nitric oxide. The endogenous nitrovasodilator and a new cellular messenger.
Anesthesiology 1991;75(6):927-31.
1991: Ross Tracey; Roger Johns; G Romero; M J Peach
Mechanism of phospholipase C-induced release of EDRF from pulmonary artery endothelium.
The American journal of physiology 1991;261(5 Pt 1):C927-35.
1991: A Rengasamy; Roger Johns
Characterization of endothelium-derived relaxing factor/nitric oxide synthase from bovine cerebellum and mechanism of modulation by high and low oxygen tensions.
The Journal of pharmacology and experimental therapeutics 1991;259(1):310-6.
1991: D D Frankville; G B Harper; C L Lake; Roger Johns
Hemodynamic consequences of desmopressin administration after cardiopulmonary bypass.
Anesthesiology 1991;74(6):988-96.
1991: Roger Johns
Endothelium-derived relaxing factor: basic review and clinical implications.
Journal of cardiothoracic and vascular anesthesia 1991;5(1):69-79.
1991: Joel Linden; M R Prater; G W Sullivan; Roger Johns; A Patel
Contamination of adenosine deaminase by superoxide dismutase. Stabilization of endothelium-derived relaxing factor.
Biochemical pharmacology 1991;41(2):273-9.
1991: Roger Johns; A Rengasamy
Endothelium-derived relaxing factor (EDRF). Production from L-arginine.
Advances in experimental medicine and biology 1991;301():215-27.
1990: Roger Johns; M J Peach; Joel Linden; A Tichotsky
NG-monomethyl L-arginine inhibits endothelium-derived relaxing factor-stimulated cyclic GMP accumulation in cocultures of endothelial and vascular smooth muscle cells by an action specific to the endothelial cell.
Circulation research 1990;67(4):979-85.
1990: Roger Johns
Desmopressin is a potent vasorelaxant of aorta and pulmonary artery isolated from rabbit and rat.
Anesthesiology 1990;72(5):858-64.
1990: Ross Tracey; Joel Linden; M J Peach; Roger Johns
Comparison of spectrophotometric and biological assays for nitric oxide (NO) and endothelium-derived relaxing factor (EDRF): nonspecificity of the diazotization reaction for NO and failure to detect EDRF.
The Journal of pharmacology and experimental therapeutics 1990;252(3):922-8.
1989: Roger Johns; J M Linden; M J Peach
Endothelium-dependent relaxation and cyclic GMP accumulation in rabbit pulmonary artery are selectively impaired by moderate hypoxia.
Circulation research 1989;65(6):1508-15.
1989: RICHARD RIVERS; Roger Johns
The effect of sodium nitroprusside upon platelet function.
Anesthesiology 1989;71(5):805-6.
1989: M H Wills; Roger Johns; D J Stone; J C Moscicki; CA DiFazio
Vascular effects of 2-chloroprocaine and sodium metabisulfite on isolated rat aortic rings.
Regional anesthesia 1989;14(6):271-3.
1989: D J Stone; Roger Johns
Endothelium-dependent effects of halothane, enflurane, and isoflurane on isolated rat aortic vascular rings.
Anesthesiology 1989;71(1):126-32.
1989: Roger Johns
Local anesthetics inhibit endothelium-dependent vasodilation.
Anesthesiology 1989;70(5):805-11.
1989: Roger Johns; M J Peach; T Flanagan; Irving L Kron
Probing of the canine mammary artery damages endothelium and impairs vasodilation resulting from prostacyclin and endothelium-derived relaxing factor.
The Journal of thoracic and cardiovascular surgery 1989;97(2):252-8.
1988: F S D'Alauro; Roger Johns
Hypotension related to desmopressin administration following cardiopulmonary bypass.
Anesthesiology 1988;69(6):962-3.
1988: P G Milner; Nicholas Izzo; J Saye; A L Loeb; Roger Johns; M J Peach
Endothelium-dependent relaxation is independent of arachidonic acid release.
The Journal of clinical investigation 1988;81(6):1795-803.
1988: Roger Johns; Irving L Kron; R M Carey; C L Lake
Atrial myxoma: case report, brief review, and recommendations for anesthetic management.
Journal of cardiothoracic anesthesia 1988;2(2):207-12.
1988: Roger Johns; Nicholas Izzo; P J Milner; A L Loeb; M J Peach
Use of cultured cells to study the relationship between arachidonic acid and endothelium-derived relaxing factor.
The American journal of the medical sciences 1988;295(4):287-92.
1988: Roger Johns; M J Peach
Para-bromophenacyl bromide inhibits endothelium-dependent arterial relaxation and cyclic GMP accumulation by effects produced exclusively in the smooth muscle.
The Journal of pharmacology and experimental therapeutics 1988;244(3):859-65.
1987: A L Loeb; Roger Johns; P Milner; M J Peach
Endothelium-derived relaxing factor in cultured cells.
Hypertension 1987;9(6 Pt 2):III186-92.
1986: Roger Johns; W C Seyde; C A DiFazio; D E Longnecker
Dose-dependent effects of bupivacaine on rat muscle arterioles.
Anesthesiology 1986;65(2):186-91.
1986: CA DiFazio; H Carron; K R Grosslight; J C Moscicki; W R Bolding; Roger Johns
Comparison of pH-adjusted lidocaine solutions for epidural anesthesia.
Anesthesia and analgesia 1986;65(7):760-4.
1986: Roger Johns; D A Finholt; J A Stirt
Anaesthetic management of a child with dermatomyositis.
Canadian Anaesthetists' Society journal 1986;33(1):71-4.
1985: F A Berry; C L Lake; Roger Johns; B M Rogers
Mitral valve prolapse--another cause of intraoperative dysrhythmias in the pediatric patient.
Anesthesiology 1985;62(5):662-4.
1985: C Lynch; Roger Johns
Diagnostic application of an axillary block in an infant.
Anesthesiology 1985;62(4):524-6.
1985: Roger Johns; C A DiFazio; D E Longnecker
Lidocaine constricts or dilates rat arterioles in a dose-dependent manner.
Anesthesiology 1985;62(2):141-4.