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Gerald Becker

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Gerald Becker
Stable isotopic labeling of proteins for quantitative proteomic applications.
Angeliki Magklara; Ali A Mellati; Gregory A Wasney; Sheila P Little; Georgia Sotiropoulou; Gerald Becker; Eleftherios P Diamandis
Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.
Victor J Wroblewski; Derrick R Witcher; Gerald Becker; Kelly A Davis; Shenshen Dou; Radmila Micanovic; Christy M Newton; Timothy W Noblitt; John M Richardson; Ho Yeong Song; John E Hale
Decoy receptor 3 (DcR3) is proteolytically processed to a metabolic fragment having differential activities against Fas ligand and LIGHT.

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All Publications

2008: Gerald Becker
Stable isotopic labeling of proteins for quantitative proteomic applications.
Briefings in functional genomics & proteomics 2008;7(5):371-82.
2003: Angeliki Magklara; Ali A Mellati; Gregory A Wasney; Sheila P Little; Georgia Sotiropoulou; Gerald Becker; Eleftherios P Diamandis
Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.
Biochemical and biophysical research communications 2003;307(4):948-55.
2003: Victor J Wroblewski; Derrick R Witcher; Gerald Becker; Kelly A Davis; Shenshen Dou; Radmila Micanovic; Christy M Newton; Timothy W Noblitt; John M Richardson; Ho Yeong Song; John E Hale
Decoy receptor 3 (DcR3) is proteolytically processed to a metabolic fragment having differential activities against Fas ligand and LIGHT.
Biochemical pharmacology 2003;65(4):657-67.
2002: Christian M Gygi; Ilan Y Leibovitch; Robert Adlington; Jack E Baldwin; Beining Chen; William McCoull; Gareth J Pritchard; Gerald Becker; Eric P Dixon; Sheila P Little; Debra M Sutkowski; Carroll Teater; Blake Lee Neubauer
Prostate-specific antigen (PSA)-mediated proliferation, androgenic regulation and inhibitory effects of LY312340 in HOS-TE85 (TE85) human osteosarcoma cells.
Anticancer research 2002;22(5):2725-32.
2002: Amy C Porter; John-Michael Sauer; Michael D Knierman; Gerald Becker; Michael J Berna; Jingqi Bao; George Nomikos; Petra Carter; Frank P Bymaster; Andrea Baker Leese; Christian Felder
Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor.
The Journal of pharmacology and experimental therapeutics 2002;301(3):1020-4.
2002: Robert J Konrad; Fengxue Zhang; John E Hale; Michael D Knierman; Gerald Becker; Jeffrey E Kudlow
Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase.
Biochemical and biophysical research communications 2002;293(1):207-12.
2001: Robert J Konrad; joseph tolar; John E Hale; Michael D Knierman; Gerald Becker; Jeffrey E Kudlow
Purification of the O-glycosylated protein p135 and identification as O-GlcNAc transferase.
Biochemical and biophysical research communications 2001;288(5):1136-40.
2001: Robert M Adlington; Jack E Baldwin; Gerald Becker; Beining Chen; L Cheng; S L Cooper; R B Hermann; T J Howe; William McCoull; Ann M McNulty; B L Neubauer; Gareth J Pritchard
Design, synthesis, and proposed active site binding analysis of monocyclic 2-azetidinone inhibitors of prostate specific antigen.
Journal of medicinal chemistry 2001;44(10):1491-508.
2001: LL Habeck; R M Belagaje; Gerald Becker; John E Hale; LM Churgay; Maverick Ulmer; X Y Yang; KA Shackelford; John M Richardson; M G Johnson; LG Mendelsohn
Expression, purification, and characterization of active recombinant prostate-specific antigen in Pichia pastoris (yeast).
The Prostate 2001;46(4):298-306.
2000: John E Hale; Jon P Butler; Michael D Knierman; Gerald Becker
Increased sensitivity of tryptic peptide detection by MALDI-TOF mass spectrometry is achieved by conversion of lysine to homoarginine.
Analytical biochemistry 2000;287(1):110-7.
1999: J An; G Zhao; LM Churgay; J J Osborne; John E Hale; Gerald Becker; G Gold; L E Stramm; Y Shi
Threonine phosphorylations induced by RX-871024 and insulin secretagogues in betaTC6-F7 cells.
The American journal of physiology 1999;277(5 Pt 1):E862-9.
1999: D M Sutkowski; Robin L Goode; J Baniel; C Teater; P Cohen; Ann M McNulty; Hansen M Hsiung; Gerald Becker; Blake Lee Neubauer
Growth regulation of prostatic stromal cells by prostate-specific antigen.
Journal of the National Cancer Institute 1999;91(19):1663-9.
1998: T F Burke; Kim Cocke; Stephanie Lemke; E Angleton; Gerald Becker; Richard P Beckmann
Identification of a BRCA1-associated kinase with potential biological relevance.
Oncogene 1998;16(8):1031-40.
1997: Sheila P Little; E P Dixon; F Norris; W Buckley; Gerald Becker; M Johnson; J R Dobbins; T Wyrick; J R Miller; W MacKellar; D Hepburn; Jose Corvalan; D McClure; X Liu; D Stephenson; J Clemens; Edward M Johnstone
Zyme, a novel and potentially amyloidogenic enzyme cDNA isolated from Alzheimer's disease brain.
The Journal of biological chemistry 1997;272(40):25135-42.
1997: Genshi Zhao; Wu-Kuang Yeh; R H Carnahan; J Flokowitsch; Timothy I Meier; William E Alborn; Gerald Becker; SR Jaskunas
Biochemical characterization of penicillin-resistant and -sensitive penicillin-binding protein 2x transpeptidase activities of Streptococcus pneumoniae and mechanistic implications in bacterial resistance to beta-lactam antibiotics.
Journal of bacteriology 1997;179(15):4901-8.
1997: A D Kline; Gerald Becker; LM Churgay; B E Landen; D K Martin; W L Muth; Radhakrishnan Rathnachalam; John M Richardson; Brigitte E Schoner; Maverick Ulmer; John E Hale
Leptin is a four-helix bundle: secondary structure by NMR.
FEBS letters 1997;407(2):239-42.
1996: Christian Felder; A Nielsen; E M Briley; Miklós Palkovits; J Priller; Julius Axelrod; D N Nguyen; J M Richardson; R M Riggin; G A Koppel; S M Paul; Gerald Becker
Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat.
FEBS letters 1996;393(2-3):231-5.
1996: M K Sinha; Iryna L Opentanova; J P Ohannesian; JW Kolaczynski; Mark L Heiman; J Hale; Gerald Becker; R R Bowsher; T W Stephens; JF Caro
Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting.
The Journal of clinical investigation 1996;98(6):1277-82.
1995: D N Nguyen; Gerald Becker; R M Riggin
Protein mass spectrometry: applications to analytical biotechnology.
Journal of chromatography. A 1995;705(1):21-45.
1994: L Zhang; Curtis L Ashendel; Gerald Becker; D J Morré
Isolation and characterization of the principal ATPase associated with transitional endoplasmic reticulum of rat liver.
The Journal of cell biology 1994;127(6 Pt 2):1871-83.
1994: P J Burck; D H Berg; T P Luk; L M Sassmannshausen; M Wakulchik; D P Smith; H M Hsiung; Gerald Becker; D GIBSON; Elcira Villarreal
Human cytomegalovirus maturational proteinase: expression in Escherichia coli, purification, and enzymatic characterization by using peptide substrate mimics of natural cleavage sites.
Journal of virology 1994;68(5):2937-46.
1994: Srinivasan Chandrasekhar; AK Harvey; M G Johnson; Gerald Becker
Osteonectin/SPARC is a product of articular chondrocytes/cartilage and is regulated by cytokines and growth factors.
Biochimica et biophysica acta 1994;1221(1):7-14.
1994: L K Simmons; Patrick May; K J Tomaselli; Russell E Rydel; KS Fuson; E F Brigham; S Wright; I Lieberburg; Gerald Becker; D N Brems
Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro.
Molecular pharmacology 1994;45(3):373-9.
1994: M C Smith; J Giordano; J A Cook; M Wakulchik; Elcira Villarreal; Gerald Becker; K Bemis; J Labus; J S Manetta
Purification and kinetic characterization of human cytomegalovirus assemblin.
Methods in enzymology 1994;244():412-23.
1994: Gerald Becker; J R Miller; S Kovacevic; R M Ellis; A I Louis; J S Small; D H Stark; E F Roberts; T K Wyrick; J Hoskins
Characterization by electrospray mass spectrometry of human Ca(2+)-sensitive cytosolic phospholipase A2 produced in baculovirus-infected insect cells.
Bio/technology (Nature Publishing Company) 1994;12(1):69-74.
1993: Steven A Wrighton; J C Stevens; Gerald Becker; Mark R VandenBranden
Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation.
Archives of biochemistry and biophysics 1993;306(1):240-5.
1993: V J Wroblewski; R E Kaiser; Gerald Becker
Proteolysis of human growth hormone by rat thyroid gland in vitro: application of electrospray mass spectrometry and N-terminal sequencing to elucidate a metabolic pathway.
Pharmaceutical research 1993;10(8):1106-14.
1993: J Hutsul; Elizabeth A Worobec; T R Parr; Gerald Becker
Comparative analyses of Serratia spp. outer membrane porin proteins.
Canadian journal of microbiology 1993;39(4):442-7.
1992: Patrick May; B D Gitter; D C Waters; L K Simmons; Gerald Becker; J S Small; P M Robison
beta-Amyloid peptide in vitro toxicity: lot-to-lot variability.
Neurobiology of aging 1992;13(5):605-7.
1992: V J Wroblewski; M Masnyk; S S Khambatta; Gerald Becker
Mechanisms involved in degradation of human insulin by cytosolic fractions of human, monkey, and rat liver.
Diabetes 1992;41(4):539-47.
1992: Steven A Wrighton; Mark R VandenBranden; Gerald Becker; S D Black; P E Thomas
Two monoclonal antibodies recognizing different epitopes on rat cytochrome IIB1 react with human IIE1.
Molecular pharmacology 1992;41(1):76-82.
1991: J A Cook; W J Wheeler; Gerald Becker; M C Smith
Catalytic hydrogenolysis of poly-iodinated recombinant human insulin-like growth factor II (IGF-II): a potentially useful method for the tritiation of IGF-II.
Analytical biochemistry 1991;198(2):379-84.
1991: V J Wroblewski; M Masnyk; Gerald Becker
Proteolytic cleavage of human growth hormone (hGH) by rat tissues in vitro: influence on the kinetics of exogenously administered hGH.
Endocrinology 1991;129(1):465-74.
1990: F Malouin; G D Campbell; M Halpenny; Gerald Becker; T R Parr
Outer membrane and porin characteristics of Serratia marcescens grown in vitro and in rat intraperitoneal diffusion chambers.
Infection and immunity 1990;58(5):1247-53.
1990: D N Brems; P L Brown; Gerald Becker
Equilibrium denaturation of human growth hormone and its cysteine-modified forms.
The Journal of biological chemistry 1990;265(10):5504-11.
1989: N A Farid; L M Atkins; Gerald Becker; A Dinner; R E Heiney; D J Miner; R M Riggin
Liquid chromatographic control of the identity, purity and "potency" of biomolecules used as drugs.
Journal of pharmaceutical and biomedical analysis 1989;7(2):185-8.
1988: Gerald Becker; P M Tackitt; W W Bromer; D S Lefeber; R M Riggin
Isolation and characterization of a sulfoxide and a desamido derivative of biosynthetic human growth hormone.
Biotechnology and applied biochemistry 1988;10(4):326-37.
1988: A Tsarbopoulos; Gerald Becker; J L Occolowitz; I Jardine
Peptide and protein mapping by 252Cf-plasma desorption mass spectrometry.
Analytical biochemistry 1988;171(1):113-23.
1988: H M Hsiung; Gerald Becker
Secretion and folding of human growth hormone in Escherichia coli.
Biotechnology & genetic engineering reviews 1988;6():43-65.
1987: Gerald Becker; R R Bowsher; W C Mackellar; M L Poor; P M Tackitt; R M Riggin
Chemical, physical, and biological characterization of a dimeric form of biosynthetic human growth hormone.
Biotechnology and applied biochemistry 1987;9(6):478-87.
1986: Gerald Becker; H M Hsiung
Expression, secretion and folding of human growth hormone in Escherichia coli. Purification and characterization.
FEBS letters 1986;204(1):145-50.
1980: Gerald Becker; R L Lester
Biosynthesis of phosphoinositol-containing sphingolipids from phosphatidylinositol by a membrane preparation from Saccharomyces cerevisiae.
Journal of bacteriology 1980;142(3):747-54.
1977: Gerald Becker; R L Lester
Changes in phospholipids of Saccharomyces cerevisiae associated with inositol-less death.
The Journal of biological chemistry 1977;252(23):8684-91.
1973: E O Magarian; Gerald Becker; L Diamond
Anticonvulsant properties of Mannich base derivatives of 2-phenylsuccinimide. 3.
Journal of pharmaceutical sciences 1973;62(2):325-7.