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Gal Markel

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Gal Markel; Antonio Brucato; Massimo Imazio; Yehuda Adler
Prevention of recurrent pericarditis with colchicine in 2012.
Michal J Besser; Orit Harari-Steinberg; Ron Loewenthal; Arnon Nagler; Rona Ortenberg; Jacob Schachter; Tsipi Shoham; Arkadi Yakirevitch; Naama Zabari; Gal Markel
Development of allogeneic NK cell adoptive transfer therapy in metastatic melanoma patients: in vitro preclinical optimization studies.
Orit Itzhaki; Adva Kubi; Camilla Avivi; Eytan Ben-Ami; Michal J Besser; Eyal Greenberg; Rona Ortenberg; Jacob Schachter; Bruria Shalmon; Ronnie Shapira-Frommer; Avraham J Treves; Gal Markel
Nicotinamide inhibits vasculogenic mimicry, an alternative vascularization pathway observed in highly aggressive melanoma.

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All Publications

2013: Gal Markel; Antonio Brucato; Massimo Imazio; Yehuda Adler
Prevention of recurrent pericarditis with colchicine in 2012.
Clinical cardiology 2013;36(3):125-8.
2013: Michal J Besser; Orit Harari-Steinberg; Ron Loewenthal; Arnon Nagler; Rona Ortenberg; Jacob Schachter; Tsipi Shoham; Arkadi Yakirevitch; Naama Zabari; Gal Markel
Development of allogeneic NK cell adoptive transfer therapy in metastatic melanoma patients: in vitro preclinical optimization studies.
PloS one 2013;8(3):e57922.
2013: Orit Itzhaki; Adva Kubi; Camilla Avivi; Eytan Ben-Ami; Michal J Besser; Eyal Greenberg; Rona Ortenberg; Jacob Schachter; Bruria Shalmon; Ronnie Shapira-Frommer; Avraham J Treves; Gal Markel
Nicotinamide inhibits vasculogenic mimicry, an alternative vascularization pathway observed in highly aggressive melanoma.
PloS one 2013;8(2):e57160.
2013: Orit Itzhaki; Daphna Levy; Gal Markel; Jacob Schachter; Avraham J Treves; Dragoslav Zikich; Michal J Besser
Adoptive T-cell transfer in melanoma.
Immunotherapy 2013;5(1):79-90.
2012: Sivan Sapoznik; Jacob Schachter; Rona Ortenberg; Camila Avivi; Iris Barshack; Michal J Besser; Cyrille J Cohen; Gilli Galore-Haskel; Stav Kozlovski; Daphna Levy; Gal Markel
CXCR1 as a novel target for directing reactive T cells toward melanoma: implications for adoptive cell transfer immunotherapy.
Cancer immunology, immunotherapy : CII 2012;61(10):1833-47.
2012: Rona Ortenberg; Lee Raz; Yair Sapir; Sivan Sapoznik; Jacob Schachter; Camila Avivi; Iris Barshack; Ayelet Ben Arav; Tehila Ben-Moshe; Yackov Berkun; Michal J Besser; Liat Hershkovitz; Gal Markel
Novel immunotherapy for malignant melanoma with a monoclonal antibody that blocks CEACAM1 homophilic interactions.
Molecular cancer therapeutics 2012;11(6):1300-10.
2012: Sivan Sapoznik; Jacob Schachter; Rona Ortenberg; Tehila Ben-Moshe; Michal J Besser; Ohad Hammer; Gal Markel
Novel anti-melanoma immunotherapies: disarming tumor escape mechanisms.
Clinical & developmental immunology 2012;2012():818214.
2012: Sivan Sapoznik; J Schachter; R Ortenberg; Gal Markel
CEACAM1 in malignant melanoma: a diagnostic and therapeutic target.
Current topics in medicinal chemistry 2012;12(1):3-10.
2011: Orit Itzhaki; Einat Hovav; Yaara Ziporen; Daphna Levy; Adva Kubi; Dragoslav Zikich; Liat Hershkovitz; Avraham J Treves; Bruria Shalmon; Douglas Zippel; Gal Markel; Ronnie Shapira-Frommer; Jacob Schachter; Michal J Besser
Establishment and large-scale expansion of minimally cultured "young" tumor infiltrating lymphocytes for adoptive transfer therapy.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2011;34(2):212-20.
2011: Eyal Greenberg; Gal Markel; Gideon Rechavi; Jacob Schachter; Oz Solomon; Ninette Amariglio; Eran Eyal
Mutagen-specific mutation signature determines global microRNA binding.
PloS one 2011;6(11):e27400.
2011: Eyal Greenberg; Liat Hershkovitz; Orit Itzhaki; Steven Hajdu; Yael Nemlich; Rona Ortenberg; Nir Gefen; Liat Edry; Shira Modai; Yona Keisari; Michal J Besser; Jacob Schachter; Noam Shomron; Gal Markel
Regulation of cancer aggressive features in melanoma cells by microRNAs.
PloS one 2011;6(4):e18936.
2010: Michal J Besser; Ronnie Shapira-Frommer; Avraham J Treves; Dov Zippel; Orit Itzhaki; Liat Hershkovitz; Daphna Levy; Adva Kubi; Einat Hovav; Natalia Chermoshniuk; Bruria Shalmon; Izhar Hardan; Raphael Catane; Gal Markel; Sara Apter; Alon Ben-Nun; Iryna Kuchuk; Avichai Shimoni; Arnon Nagler; Jacob Schachter
Clinical responses in a phase II study using adoptive transfer of short-term cultured tumor infiltration lymphocytes in metastatic melanoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(9):2646-55.
2010: Gal Markel; Rona Ortenberg; Rachel Seidman; Sivan Sapoznik; Nira Koren-Morag; Michal J Besser; Jair Bar; Ronnie Shapira; Adva Kubi; Gil Nardini; Ariel Tessone; Avraham J Treves; Eyal Winkler; Arie Orenstein; Jacob Schachter
Systemic dysregulation of CEACAM1 in melanoma patients.
Cancer immunology, immunotherapy : CII 2010;59(2):215-30.
2010: Gal Markel; Erez Bar-Haim; Eran Zahavy; Hila Cohen; Ofer Cohen; Avigdor Shafferman; Baruch Velan
The involvement of IL-17A in the murine response to sub-lethal inhalational infection with Francisella tularensis.
PloS one 2010;5(6):e11176.
2009: Shai Shrot; Gal Markel; Tsvika Dushnitsky; Amir Krivoy
The possible use of oximes as antidotal therapy in organophosphate-induced brain damage.
Neurotoxicology 2009;30(2):167-73.
2009: Arik Eisenkraft; Amir Krivoy; Aviv Vidan; Eyal Robenshtok; Ariel Hourvitz; Tsvika Dushnitsky; Gal Markel
Phase I study of a topical skin protectant against chemical warfare agents.
Military medicine 2009;174(1):47-52.
2008: Erez Bar-Haim; Orit Gat; Gal Markel; Hila Cohen; Avigdor Shafferman; Baruch Velan
Interrelationship between dendritic cell trafficking and Francisella tularensis dissemination following airway infection.
PLoS pathogens 2008;4(11):e1000211.
2008: Igor Makarovsky; Gal Markel; Tsvika Dushnitsky; Arik Eisenkraft
Ammonia--when something smells wrong.
The Israel Medical Association journal : IMAJ 2008;10(7):537-43.
2008: Igor Makarovsky; Gal Markel; Tsvika Dushnitsky; Arik Eisenkraft
Hydrogen fluoride--the protoplasmic poison.
The Israel Medical Association journal : IMAJ 2008;10(5):381-5.
2008: Igor Makarovsky; Gal Markel; Tsvika Dushnitsky; Arik Eisenkraft
Hydrazine--the space era agent.
The Israel Medical Association journal : IMAJ 2008;10(4):302-6.
2008: Igor Makarovsky; Gal Markel; Azik Hoffman; Ophir Schein; Tal Brosh Nissimov; Zeev Tashma; Tsvika Dushnitsky; Arik Eisenkraft
Strychnine--a killer from the past.
The Israel Medical Association journal : IMAJ 2008;10(2):142-5.
2008: Tal I Arnon; Gal Markel; Ahuva Bar-Ilan; Jacob Hanna; Eyal Fima; Fabrice Benchetrit; Ruth Galili; Adelheid Cerwenka; Daniel Benharroch; Netta Sion-Vardy; Angel Porgador; Ofer Mandelboim
Harnessing soluble NK cell killer receptors for the generation of novel cancer immune therapy.
PloS one 2008;3(5):e2150.
2008: Gal Markel; Massimo Imazio; Antonio Brucato; Yehuda Adler
Colchicine for the prevention of recurrent pericarditis.
The Israel Medical Association journal : IMAJ 2008;10(1):69-72.
2007: Boaz Nachmias; Sa'ar Mizrahi; Meital Elmalech; Itay Lazar; Yaqoub Ashhab; Roi Gazit; Gal Markel; Dina Ben-Yehuda; Ofer Mandelboim
Manipulation of NK cytotoxicity by the IAP family member Livin.
European journal of immunology 2007;37(12):3467-76.
2007: Igor Makarovsky; Gal Markel; Azik Hoffman; Ophir Schein; Arseny Finkelstien; Tal Brosh Nissimov; Zeev Tashma; Tsvika Dushnitsky; Arik Eisenkraft
Osmium tetroxide: a new kind of weapon.
The Israel Medical Association journal : IMAJ 2007;9(10):750-2.
2007: Noam Stern-Ginossar; Shlomo Nedvetzki; Gal Markel; Roi Gazit; Gili Betser-Cohen; Hagit Achdout; Memet Aker; Richard S Blumberg; Daniel M Davis; Ben J Appelmelk; Ofer Mandelboim
Intercellular transfer of carcinoembryonic antigen from tumor cells to NK cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(7):4424-34.
2007: Igor Makarovsky; Gal Markel; Azik Hoffman; Ophir Schein; Tal Brosh Nissimov; Arseny Finkelstien; Zeev Tashma; Tsvika Dushnitsky; Arik Eisenkraft
Bromine--the red cloud approaching.
The Israel Medical Association journal : IMAJ 2007;9(9):677-9.
2007: Arik Eisenkraft; Gal Markel; Shirley Simovich; Ido Layish; Azik Hoffman; Arseny Finkelstein; ERAN ROTMAN; Tsvika Dushnitsky; Amir Krivoy
Mobile chemical detector (AP2C+SP4E) as an aid for medical decision making in the battlefield.
Military medicine 2007;172(9):997-1001.
2007: Sa'ar Mizrahi; Gal Markel; Angel Porgador; Yuri Bushkin; Ofer Mandelboim
CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72.
PloS one 2007;2(9):e818.
2006: Gal Markel; Rachel Seidman; Noam Stern; Tali Cohen-Sinai; Orit Izhaki; Gil Katz; Michal Besser; Avraham J Treves; Richard S Blumberg; Ron Loewenthal; Ofer Mandelboim; Arie Orenstein; Jacob Schachter
Inhibition of human tumor-infiltrating lymphocyte effector functions by the homophilic carcinoembryonic cell adhesion molecule 1 interactions.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(9):6062-71.
2006: Tal I Arnon; Gal Markel; Ofer Mandelboim
Tumor and viral recognition by natural killer cells receptors.
Seminars in cancer biology 2006;16(5):348-58.
2005: Niva Azuz-Lieberman; Gal Markel; Sa'ar Mizrahi; Roi Gazit; Jacob Hanna; Hagit Achdout; Raizy Gruda; Gil Katz; Tal I Arnon; Shosh Battat; Ehud Zamir; Muhammed Adawi; Reuven Mader; Ofer Mandelboim
The involvement of NK cells in ankylosing spondylitis.
International immunology 2005;17(7):837-45.
2005: Noam Stern; Gal Markel; Tal I Arnon; Raizy Gruda; Henry Wong; Scott D Gray-Owen; Ofer Mandelboim
Carcinoembryonic antigen (CEA) inhibits NK killing via interaction with CEA-related cell adhesion molecule 1.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):6692-701.
2005: Tal I Arnon; Hagit Achdout; Ofer Levi; Gal Markel; Niveen Saleh; Gil Katz; Roi Gazit; Tsufit Gonen-Gross; Jacob Hanna; Efrat Nahari; Angel Porgador; Alik Honigman; Bodo Plachter; Dror Mevorach; Dana G Wolf; Ofer Mandelboim
Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus.
Nature immunology 2005;6(5):515-23.
2004: Gal Markel; Raizy Gruda; Hagit Achdout; Gil Katz; Morris Nechama; Richard S Blumberg; Robert Kammerer; Wolfgang Zimmermann; Ofer Mandelboim
The critical role of residues 43R and 44Q of carcinoembryonic antigen cell adhesion molecules-1 in the protection from killing by human NK cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):3732-9.
2004: Gil Katz; Roi Gazit; Tal I Arnon; Tsufit Gonen-Gross; Gabi Tarcic; Gal Markel; Raizy Gruda; Hagit Achdout; Olga Drize; Sharon Merims; Ofer Mandelboim
MHC class I-independent recognition of NK-activating receptor KIR2DS4.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):1819-25.
2004: Gal Markel; Hagit Achdout; Gil Katz; Khoon-Lin Ling; Mariolina Salio; Raizy Gruda; Roi Gazit; Sa'ar Mizrahi; Jacob Hanna; Tsufit Gonen-Gross; Tal I Arnon; Niva Lieberman; Noam Stren; Boaz Nachmias; Richard S Blumberg; Guy Steuer; Hannah Blau; Vincenzo Cerundolo; Huda Mussaffi; Ofer Mandelboim
Biological function of the soluble CEACAM1 protein and implications in TAP2-deficient patients.
European journal of immunology 2004;34(8):2138-48.
2004: Roi Gazit; Hagai Rechnitzer; Hagit Achdout; Avigail Katzenell; Gil Katz; Gal Markel; Tal I Arnon; Tsufit Gonen-Gross; Sa'ar Mizrahi; Raizy Gruda; Shlomo Rottem; Ofer Mandelboim
Recognition of Mycoplasma hyorhinis by CD99-Fc molecule.
European journal of immunology 2004;34(7):2032-40.
2004: Roi Gazit; Ben-Zion Garty; Yehudit Monselise; Vered Hoffer; Yaron Finkelstein; Gal Markel; Gil Katz; Jacob Hanna; Hagit Achdout; Raizy Gruda; Tsufit Gonen-Gross; Ofer Mandelboim
Expression of KIR2DL1 on the entire NK cell population: a possible novel immunodeficiency syndrome.
Blood 2004;103(5):1965-6.
2004: Gal Markel; Huda Mussaffi; Khoon-Lin Ling; Mariolina Salio; Stephan D Gadola; Guy Steuer; Hannah Blau; Hagit Achdout; María de Miguel; Tsufit Gonen-Gross; Jacob Hanna; Tal I Arnon; Udi Qimron; Ilan Volovitz; Lea Eisenbach; Richard S Blumberg; Angel Porgador; Vincenzo Cerundolo; Ofer Mandelboim
The mechanisms controlling NK cell autoreactivity in TAP2-deficient patients.
Blood 2004;103(5):1770-8.
2003: Tsufit Gonen-Gross; Roi Gazit; Hagit Achdout; Jacob Hanna; Sa'ar Mizrahi; Gal Markel; Václav Horejsí; Ofer Mandelboim
Special organization of the HLA-G protein on the cell surface.
Human immunology 2003;64(11):1011-6.
2003: Jacob Hanna; Ori Wald; Debra Goldman-Wohl; Diana Prus; Gal Markel; Roi Gazit; Gil Katz; Ronit Haimov-Kochman; Nobutaka Fujii; Simcha Yagel; Amnon Peled; Ofer Mandelboim
CXCL12 expression by invasive trophoblasts induces the specific migration of CD16- human natural killer cells.
Blood 2003;102(5):1569-77.
2003: Tsufit Gonen-Gross; Hagit Achdout; Roi Gazit; Jacob Hanna; Sa'ar Mizrahi; Gal Markel; Debra Goldman-Wohl; Simcha Yagel; Václav Horejsí; Ofer Levy; Michal Baniyash; Ofer Mandelboim
Complexes of HLA-G protein on the cell surface are important for leukocyte Ig-like receptor-1 function.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1343-51.
2003: Hagit Achdout; Tal I Arnon; Gal Markel; Tsufit Gonen-Gross; Gil Katz; Niva Lieberman; Roi Gazit; Aviva Joseph; Eli Kedar; Ofer Mandelboim
Enhanced recognition of human NK receptors after influenza virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):915-23.
2002: Gal Markel; Dana Wolf; Jacob Hanna; Roi Gazit; Debra Goldman-Wohl; Yuval Lavy; Simcha Yagel; Ofer Mandelboim
Pivotal role of CEACAM1 protein in the inhibition of activated decidual lymphocyte functions.
The Journal of clinical investigation 2002;110(7):943-53.
2002: Micha Drukker; Gil Katz; Achia Urbach; Maya Schuldiner; Gal Markel; Joseph Itskovitz-Eldor; Benjamin E Reubinoff; Ofer Mandelboim; Nissim Benvenisty
Characterization of the expression of MHC proteins in human embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):9864-9.
2002: Gal Markel; Niva Lieberman; Gil Katz; Tal I Arnon; Michal Lotem; Olga Drize; Richard S Blumberg; Erez Bar-Haim; Reuven Mader; Lea Eisenbach; Ofer Mandelboim
CD66a interactions between human melanoma and NK cells: a novel class I MHC-independent inhibitory mechanism of cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(6):2803-10.
2001: Gil Katz; Gal Markel; Sa'ar Mizrahi; Tal I Arnon; Ofer Mandelboim
Recognition of HLA-Cw4 but not HLA-Cw6 by the NK cell receptor killer cell Ig-like receptor two-domain short tail number 4.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7260-7.