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James Bunzow

Research Profile

Chemicals & Drugs

Living Beings

Rats
Mouse

Procedures

Cloning, Molecular

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Anatomy

Cell Line

Physiology

Phenomena

Nucleic Acid Hybridization

Co-author Network

Publications

TOP 3
Edwin S. Tan; John C Naylor; Eli S Groban; James R Bunzow; Matthew P Jacobson; David K Grandy; Thomas S Scanlan
The molecular basis of species-specific ligand activation of trace amine-associated receptor 1 (TAAR(1)).
Edwin S. Tan; Motonori Miyakawa; James R Bunzow; David K Grandy; Thomas S Scanlan
Exploring the structure-activity relationship of the ethylamine portion of 3-iodothyronamine for rat and mouse trace amine-associated receptor 1.
E Reese; James R Bunzow; Seksiri Arttamangkul; MS Sonders; David K Grandy
Trace amine-associated receptor 1 displays species-dependent stereoselectivity for isomers of methamphetamine, amphetamine, and para-hydroxyamphetamine.

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All Publications

2009: Edwin S. Tan; John C Naylor; Eli S Groban; James R Bunzow; Matthew P Jacobson; David K Grandy; Thomas S Scanlan
The molecular basis of species-specific ligand activation of trace amine-associated receptor 1 (TAAR(1)).
ACS chemical biology 2009;4(3):209-20.
2007: Edwin S. Tan; Motonori Miyakawa; James R Bunzow; David K Grandy; Thomas S Scanlan
Exploring the structure-activity relationship of the ethylamine portion of 3-iodothyronamine for rat and mouse trace amine-associated receptor 1.
Journal of medicinal chemistry 2007;50(12):2787-98.
2007: E Reese; James R Bunzow; Seksiri Arttamangkul; MS Sonders; David K Grandy
Trace amine-associated receptor 1 displays species-dependent stereoselectivity for isomers of methamphetamine, amphetamine, and para-hydroxyamphetamine.
The Journal of pharmacology and experimental therapeutics 2007;321(1):178-86.
2006: Matthew E Hart; Katherine L Suchland; Motonori Miyakawa; James R Bunzow; David K Grandy; Thomas S Scanlan
Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues.
Journal of medicinal chemistry 2006;49(3):1101-12.
2005: Lothar Lindemann; Martin Ebeling; Nicole A Kratochwil; James R Bunzow; David K Grandy; Marius C Hoener
Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.
Genomics 2005;85(3):372-85.
2004: Thomas S Scanlan; Katherine L Suchland; Matthew E Hart; Grazia Chiellini; Yong Huang; Paul J Kruzich; Sabina Frascarelli; Dane A Crossley; James R Bunzow; Simonetta Ronca-Testoni; Emil T Lin; Daniel Hatton; Riccardo Zucchi; David K Grandy
3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone.
Nature medicine 2004;10(6):638-42.
2002: Ming Li; Chuanyu Li; Paul Weingarten; James R Bunzow; David K Grandy; Qun-Yong Zhou
Association of dopamine D(3) receptors with actin-binding protein 280 (ABP-280).
Biochemical pharmacology 2002;63(5):859-63.
2001: James R Bunzow; MS Sonders; Seksiri Arttamangkul; L M Harrison; G Zhang; DI Quigley; T Darland; Katherine L Suchland; S Pasumamula; James L Kennedy; Susan B Olson; R Ellen Magenis; Susan Amara; David K Grandy
Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor.
Molecular pharmacology 2001;60(6):1181-8.
2001: Marcelo Rubinstein; Carlos Cepeda; Raymond S Hurst; J Flores-Hernandez; Marjorie A Ariano; Tomás L Falzone; Laura B Kozell; Charles K Meshul; James R Bunzow; Malcolm J Low; Michael S Levine; David K Grandy
Dopamine D4 receptor-deficient mice display cortical hyperexcitability.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(11):3756-63.
2001: David K Grandy; James R Bunzow; R L Dorit
PCR cloning of neural gene products.
Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.] 2001;Chapter 4():Unit 4.2.
1998: M A Kelly; Marcelo Rubinstein; Tamara J Phillips; Christina N Lessov; Sue Burkhart-Kasch; G Zhang; James R Bunzow; Y Fang; G A Gerhardt; David K Grandy; Malcolm J Low
Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage, genetic background, and developmental adaptations.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(9):3470-9.
1997: Marcelo Rubinstein; Tamara J Phillips; James R Bunzow; Tomás L Falzone; G Dziewczapolski; G Zhang; Y Fang; J L Larson; J A McDougall; J A Chester; C Saez; T A Pugsley; Oscar S Gershanik; Malcolm J Low; David K Grandy
Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine.
Cell 1997;90(6):991-1001.
1997: Seung-Yeol Nah; A Unteutsch; James R Bunzow; S P Cook; D W Beacham; David K Grandy
Mu and delta opioids but not kappa opioid inhibit voltage-activated Ba2+ currents in neuronal F-11 cell.
Brain research 1997;766(1-2):66-71.
1997: M A Kelly; M Rubinstein; Sylvia Asa; G Zhang; C Saez; James R Bunzow; Richard G Allen; Robert Hnasko; Nira Ben-Jonathan; David K Grandy; Malcolm J Low
Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice.
Neuron 1997;19(1):103-13.
1995: Rainer K Reinscheid; Hans-Peter Nothacker; Anne Bourson; A Ardati; R A Henningsen; James R Bunzow; David K Grandy; H Langen; FJ Monsma; Olivier Civelli
Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.
Science (New York, N.Y.) 1995;270(5237):792-4.
1995: C Bouvier; James R Bunzow; H C Guan; A Unteutsch; Olivier Civelli; David K Grandy; Hubert H M Van Tol
Functional characterization of the human dopamine D4.2 receptor using vaccinia virus as an expression system.
European journal of pharmacology 1995;290(1):11-7.
1995: James R Bunzow; G Zhang; C Bouvier; C Saez; Oline K Ronnekleiv; Martin J Kelly; David K Grandy
Characterization and distribution of a cloned rat mu-opioid receptor.
Journal of neurochemistry 1995;64(1):14-24.
1994: V Asghari; O Schoots; S van Kats; K Ohara; V Jovanovic; Hong-Chang Guan; James R Bunzow; Arturas Petronis; Hubert H M Van Tol
Dopamine D4 receptor repeat: analysis of different native and mutant forms of the human and rat genes.
Molecular pharmacology 1994;46(2):364-73.
1994: James R Bunzow; C Saez; M Mortrud; C Bouvier; John T Williams; Malcolm J Low; David K Grandy
Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type.
FEBS letters 1994;347(2-3):284-8.
1994: T E Porter; David K Grandy; James R Bunzow; C D Wiles; Olivier Civelli; L Stephen Frawley
Evidence that stimulatory dopamine receptors may be involved in the regulation of prolactin secretion.
Endocrinology 1994;134(3):1263-8.
1994: Ray E Hershberger; B L Newman; Tullio Florio; James R Bunzow; Olivier Civelli; Xiao-Jiang Li; Michael Forte; Philip J S Stork
The somatostatin receptors SSTR1 and SSTR2 are coupled to inhibition of adenylyl cyclase in Chinese hamster ovary cells via pertussis toxin-sensitive pathways.
Endocrinology 1994;134(3):1277-85.
1993: C A Fox; A Mansour; Robert C Thompson; James R Bunzow; Olivier Civelli; Stanley J Watson Jr
The distribution of dopamine D2 receptor heteronuclear RNA (hnRNA) in the rat brain.
Journal of chemical neuroanatomy 1993;6(6):363-73.
1993: Olivier Civelli; James R Bunzow; David K Grandy
Molecular diversity of the dopamine receptors.
Annual review of pharmacology and toxicology 1993;33():281-307.
1992: Hubert H M Van Tol; C M Wu; H C Guan; K Ohara; James R Bunzow; Olivier Civelli; James L Kennedy; Philip Seeman; Hyman B Niznik; V Jovanovic
Multiple dopamine D4 receptor variants in the human population.
Nature 1992;358(6382):149-52.
1992: Olivier Civelli; James R Bunzow; Q Y Zhou; David K Grandy
The diversity of the dopamine receptors.
NIDA research monograph 1992;126():23-33.
1991: James Meador-Woodruff; A Mansour; Daniel J Healy; R Kuehn; Q Y Zhou; James R Bunzow; Huda Akil; Olivier Civelli; Stanley J Watson Jr
Comparison of the distributions of D1 and D2 dopamine receptor mRNAs in rat brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1991;5(4):231-42.
1991: David K Grandy; Y A Zhang; C Bouvier; Q Y Zhou; R A Johnson; L Allen; Kari J Buck; James R Bunzow; J Salon; Olivier Civelli
Multiple human D5 dopamine receptor genes: a functional receptor and two pseudogenes.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):9175-9.
1991: Olivier Civelli; James R Bunzow; David K Grandy; Q Y Zhou; Hubert H M Van Tol
Molecular biology of the dopamine receptors.
European journal of pharmacology 1991;207(4):277-86.
1991: Hubert H M Van Tol; James R Bunzow; Hong-Chang Guan; Roger K Sunahara; Philip Seeman; Hyman B Niznik; Olivier Civelli
Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine.
Nature 1991;350(6319):610-4.
1991: Olivier Civelli; James R Bunzow; P Albert; Hubert H M Van Tol; David K Grandy
Molecular biology of the dopamine D2 receptor.
NIDA research monograph 1991;111():45-53.
1990: Q Y Zhou; David K Grandy; L Thambi; J A Kushner; Hubert H M Van Tol; Roger D Cone; D Pribnow; J Salon; James R Bunzow; Olivier Civelli
Cloning and expression of human and rat D1 dopamine receptors.
Nature 1990;347(6288):76-80.
1990: David K Grandy; E Hanneman; James R Bunzow; Marjorie Shih; Curtis A Machida; J M Bidlack; Olivier Civelli
Purification, cloning, and tissue distribution of a 23-kDa rat protein isolated by morphine affinity chromatography.
Molecular endocrinology (Baltimore, Md.) 1990;4(9):1370-6.
1990: Curtis A Machida; James R Bunzow; Robert Searles; Hubert H M Van Tol; B Tester; Kim A Neve; P Teal; V Nipper; Olivier Civelli
Molecular cloning and expression of the rat beta 1-adrenergic receptor gene.
The Journal of biological chemistry 1990;265(22):12960-5.
1990: A Mansour; James Meador-Woodruff; James R Bunzow; Olivier Civelli; Huda Akil; Stanley J Watson Jr
Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization-receptor autoradiographic analysis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(8):2587-600.
1990: L Vallar; C Muca; M Magni; P Albert; James R Bunzow; Jacopo Meldolesi; Olivier Civelli
Differential coupling of dopaminergic D2 receptors expressed in different cell types. Stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis in LtK- fibroblasts, hyperpolarization, and cytosolic-free Ca2+ concentration decrease in GH4C1 cells.
The Journal of biological chemistry 1990;265(18):10320-6.
1990: Paul R Albert; Q Y Zhou; Hubert H M Van Tol; James R Bunzow; Olivier Civelli
Cloning, functional expression, and mRNA tissue distribution of the rat 5-hydroxytryptamine1A receptor gene.
The Journal of biological chemistry 1990;265(10):5825-32.
1990: Paul R Albert; Kim A Neve; James R Bunzow; Olivier Civelli
Coupling of a cloned rat dopamine-D2 receptor to inhibition of adenylyl cyclase and prolactin secretion.
The Journal of biological chemistry 1990;265(4):2098-104.
1990: A Mansour; James Meador-Woodruff; D M Camp; Terry E Robinson; James R Bunzow; Hubert H M Van Tol; Olivier Civelli; Huda Akil; Stanley J Watson Jr
The effects of nigrostriatal 6-hydroxydopamine lesions on dopamine D2 receptor mRNA and opioid systems.
Progress in clinical and biological research 1990;328():227-30.
1989: David K Grandy; M A Marchionni; H Makam; R E Stofko; M Alfano; L Frothingham; JB Fischer; K J Burke-Howie; James R Bunzow; A C Server
Cloning of the cDNA and gene for a human D2 dopamine receptor.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):9762-6.
1989: David K Grandy; M Litt; L Allen; James R Bunzow; M Marchionni; H Makam; L Reed; R Ellen Magenis; Olivier Civelli
The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP.
American journal of human genetics 1989;45(5):778-85.
1989: James Meador-Woodruff; A Mansour; James R Bunzow; Hubert H M Van Tol; Stanley J Watson Jr; Olivier Civelli
Distribution of D2 dopamine receptor mRNA in rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7625-8.
1989: Kim A Neve; R A Henningsen; James R Bunzow; Olivier Civelli
Functional characterization of a rat dopamine D-2 receptor cDNA expressed in a mammalian cell line.
Molecular pharmacology 1989;36(3):446-51.
1989: Curtis A Machida; James R Bunzow; E Hanneman; David K Grandy; Olivier Civelli
Replica filter screening technique to detect transfected cells expressing beta 2-adrenergic receptor.
DNA (Mary Ann Liebert, Inc.) 1989;8(6):447-55.
1988: James R Bunzow; Hubert H M Van Tol; David K Grandy; P Albert; J Salon; M Christie; Curtis A Machida; Kim A Neve; Olivier Civelli
Cloning and expression of a rat D2 dopamine receptor cDNA.
Nature 1988;336(6201):783-7.
1988: Curtis A Machida; J Salon; David K Grandy; James R Bunzow; P Albert; E Hanneman; Olivier Civelli
Three technical approaches for cloning opioid receptors.
NIDA research monograph 1988;87():93-110.
1987: Olivier Civelli; Curtis A Machida; James R Bunzow; P Albert; E Hanneman; J Salon; J Bidlack; David K Grandy
The next frontier in the molecular biology of the opioid system. The opioid receptors.
Molecular neurobiology 1987;1(4):373-91.