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Giuseppe Gasparre

Research Profile

Chemicals & Drugs

Disorders

Physiology

Anatomy

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Genes & Molecular Sequences

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Genomics

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Publications

TOP 3
Anna Ghelli; Luisa Iommarini; Ivana Kurelac; Alessandra Marchesini; Andrea Martinuzzi; Anna Maria Porcelli; Maria Antonietta Calvaruso; Fevzi Daldal; Vera De Nardo; Giuseppe Gasparre; Nur Selamoglu; Concetta V Tropeano; John Vissing; Flemming Wibrand; Claudia Zanna; Michela Rugolo
The cytochrome b p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes.
Lucia Artuso; Rosa Capozzo; Paola Favia; Giuseppe Gasparre; Giancarlo Logroscino; Luigi Serlenga; Isabella Simone; Stefano Zoccolella; Angela Amati; Vittoria Petruzzella
Mitochondrial genome aberrations in skeletal muscle of patients with motor neuron disease.
Mauro Niso; Roberto Perrone; Carmen Abate; Giuseppe Cassano; Savina Ferorelli; Giuseppe Gasparre; Francesco Berardi
Investigation of σ receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines.

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All Publications

2013: Anna Ghelli; Luisa Iommarini; Ivana Kurelac; Alessandra Marchesini; Andrea Martinuzzi; Anna Maria Porcelli; Maria Antonietta Calvaruso; Fevzi Daldal; Vera De Nardo; Giuseppe Gasparre; Nur Selamoglu; Concetta V Tropeano; John Vissing; Flemming Wibrand; Claudia Zanna; Michela Rugolo
The cytochrome b p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes.
Human molecular genetics 2013;22(11):2141-51.
2013: Lucia Artuso; Rosa Capozzo; Paola Favia; Giuseppe Gasparre; Giancarlo Logroscino; Luigi Serlenga; Isabella Simone; Stefano Zoccolella; Angela Amati; Vittoria Petruzzella
Mitochondrial genome aberrations in skeletal muscle of patients with motor neuron disease.
Amyotrophic lateral sclerosis & frontotemporal degeneration 2013;14(4):261-6.
2013: Mauro Niso; Roberto Perrone; Carmen Abate; Giuseppe Cassano; Savina Ferorelli; Giuseppe Gasparre; Francesco Berardi
Investigation of σ receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines.
Bioorganic & medicinal chemistry 2013;21(7):1865-9.
2013: Nicola A Colabufo; Marialessandra Contino; Giuseppe Gasparre; Marcello Leopoldo; Maria Grazia Perrone; Francesco Berardi; Mariangela Cantore; Elena Capparelli; Giuseppe Cassano; Roberto Perrone
Naphthalenyl derivatives for hitting P-gp/MRP1/BCRP transporters.
Bioorganic & medicinal chemistry 2013;21(5):1324-32.
2013: Giuseppe Gasparre; Giorgio Lenaz; Anna Maria Porcelli; Giovanni Romeo
Relevance of mitochondrial genetics and metabolism in cancer development.
Cold Spring Harbor perspectives in biology 2013;5(2):.
2013: Ivana Kurelac; Maryou B K Lambros; Alan MacKay; Antonio Melcarne; Luca Morandi; Isabella Morra; Jorge S Reis-Filho; Giovanni Tallini; Marcella Attimonelli; Francesco Maria Calabrese; Claudio Ceccarelli; Giovanna Cenacchi; Erica Di Cesare; Giuseppe Gasparre
Somatic complex I disruptive mitochondrial DNA mutations are modifiers of tumorigenesis that correlate with low genomic instability in pituitary adenomas.
Human molecular genetics 2013;22(2):226-38.
2013: Luisa Iommarini; Ivana Kurelac; Maria Antonietta Calvaruso; Giuseppe Gasparre; Anna Maria Porcelli
Complex I impairment in mitochondrial diseases and cancer: parallel roads leading to different outcomes.
The international journal of biochemistry & cell biology 2013;45(1):47-63.
2012: Flora Guerra; Ivana Kurelac; Anna Myriam Perrone; Donatella Santini; Claudio Zamagni; Claudio Ceccarelli; Monica Cricca; Pierandrea De Iaco; Giuseppe Gasparre
Mitochondrial DNA mutation in serous ovarian cancer: implications for mitochondria-coded genes in chemoresistance.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(36):e373-8.
2012: Vittoria Petruzzella; Roberta Piredda; Anna Maria Porcelli; Teresa Rizza; Raffaella Trentadue; Marzia Bianchi; Claudia Calabrese; Rosalba Carrozzo; Rosa Dell'Aglio; Giuseppe Gasparre; Silvana Guerriero; Lucia Artuso; Marcella Attimonelli
Deep sequencing unearths nuclear mitochondrial sequences under Leber's hereditary optic neuropathy-associated false heteroplasmic mitochondrial DNA variants.
Human molecular genetics 2012;21(17):3753-64.
2012: Giuseppe Gasparre; Carmen Abate; Francesco Berardi; Giuseppe Cassano
The sigma-1 receptor antagonist PB212 reduces the Ca²⁺-release through the inositol (1, 4, 5)-trisphosphate receptor in SK-N-SH cells.
European journal of pharmacology 2012;684(1-3):59-63.
2012: Giuseppe Gasparre; Silvia Volini; Isabella Fusaro; Stefano Galletti; Maria Grazia Benedetti
Effectiveness of ultrasound-guided injections combined with shoulder exercises in the treatment of subacromial adhesive bursitis.
Musculoskeletal surgery 2012;96 Suppl 1():S57-61.
2012: Martin Lang; Donata Luiselli; Giovanni Romeo; Marco Sazzini; Domenico Simone; Marcella Attimonelli; Alessio Boattini; Francesco Maria Calabrese; Giuseppe Gasparre
Polymorphic NumtS trace human population relationships.
Human genetics 2012;131(5):757-71.
2012: Felipe C Geyer; Ivana Kurelac; Maryou B K Lambros; Maria A Lopez-Garcia; Alan Mackay; Rachael Natrajan; Moira Ragazzi; Jorge S Reis-Filho; Alan Ashworth; Dario de Biase; Vincenzo Eusebi; Giuseppe Gasparre; Giovanni Tallini
Genomic profiling of mitochondrion-rich breast carcinoma: chromosomal changes may be relevant for mitochondria accumulation and tumour biology.
Breast cancer research and treatment 2012;132(1):15-28.
2012: Francesco Rubino; Domenico Simone; Mila Tommaseo-Ponzetta; Claudia Calabrese; Francesco Maria Calabrese; Giuseppe Gasparre; Martin Lang; Vittoria Petruzzella; Roberta Piredda; Marcella Attimonelli
HmtDB, a genomic resource for mitochondrion-based human variability studies.
Nucleic acids research 2012;40(Database issue):D1150-9.
2012: Ivana Kurelac; Martin Lang; Giovanni Romeo; Monica Santamaria; Domenico Simone; Saverio Vicario; Roberta Zuntini; Marcella Attimonelli; Claudia Calabrese; Giuseppe Gasparre
Searching for a needle in the haystack: comparing six methods to evaluate heteroplasmy in difficult sequence context.
Biotechnology advances 2012;30(1):363-71.
2011: Amalia Azzariti; Mariangela Cantore; Giuseppe Cassano; Nicola A Colabufo; Giuseppe Gasparre; Giuseppina Iannelli; Maria A Panaro; Letizia Porcelli; Anna E Quatrale; Stefania Tommasi; Angelo Paradiso
MC70 potentiates doxorubicin efficacy in colon and breast cancer in vitro treatment.
European journal of pharmacology 2011;670(1):74-84.
2011: Laura Maria Pradella; Roberta Zuntini; Claudio Ceccarelli; Serenella Cerasoli; Giuseppe Gasparre; Claudio Graziano; Pamela Magini; Iria Neri; Daniela Turchetti
Two distinct thyroid tumours in a patient with Cowden syndrome carrying both a 10q23 and a mitochondrial DNA germline deletion.
Journal of medical genetics 2011;48(11):779-82.
2011: Giuseppe Gasparre; Anna Ghelli; Luisa Iommarini; Ivana Kurelac; Pier-Luigi Lollini; Patrizia Nanni; Giordano Nicoletti; Christine M Betts; Mariantonietta Capristo; Valerio Carelli; Claudio Ceccarelli; Carla De Giovanni; Giovanni Romeo; Michela Rugolo; Katia Scotlandi; Anna Maria Porcelli
A mutation threshold distinguishes the antitumorigenic effects of the mitochondrial gene MTND1, an oncojanus function.
Cancer research 2011;71(19):6220-9.
2011: Flora Guerra; Ivana Kurelac; Pamela Magini; Donatella Santini; Claudio Ceccarelli; Antonella Cormio; Giuseppe Gasparre
Mitochondrial DNA genotyping reveals synchronous nature of simultaneously detected endometrial and ovarian cancers.
Gynecologic oncology 2011;122(2):457-8.
2011: Ivana Kurelac; Giovanni Romeo; Giuseppe Gasparre
Mitochondrial metabolism and cancer.
Mitochondrion 2011;11(4):635-7.
2011: Flora Guerra; Ivana Kurelac; Antonella Cormio; Roberta Zuntini; Laura Benedetta Amato; Claudio Ceccarelli; Donatella Santini; Gennaro Cormio; Flavio Fracasso; Luigi Selvaggi; Leonardo Resta; Marcella Attimonelli; Maria Nicola Gadaleta; Giuseppe Gasparre
Placing mitochondrial DNA mutations within the progression model of type I endometrial carcinoma.
Human molecular genetics 2011;20(12):2394-405.
2011: Giuseppe Gasparre; Giovanni Romeo; Michela Rugolo; Anna Maria Porcelli
Learning from oncocytic tumors: Why choose inefficient mitochondria?
Biochimica et biophysica acta 2011;1807(6):633-42.
2011: Anna Bartoletti-Stella; Nunzio C M Salfi; Claudio Ceccarelli; Marcella Attimonelli; Giovanni Romeo; Giuseppe Gasparre
Mitochondrial DNA mutations in oncocytic adnexal lacrimal glands of the conjunctiva.
Archives of ophthalmology 2011;129(5):664-6.
2011: Domenico Simone; Francesco Maria Calabrese; Giuseppe Gasparre; Martin Lang; Marcella Attimonelli
The reference human nuclear mitochondrial sequences compilation validated and implemented on the UCSC genome browser.
BMC genomics 2011;12():517.
2011: Ghizlane Elachouri; Sara Vidoni; Claudia Zanna; Alexandre Pattyn; Hassan Boukhaddaoui; Karen Gaget; Patrick Yu-Wai-Man; Giuseppe Gasparre; Emmanuelle Sarzi; Cécile Delettre; Aurélien Olichon; Dominique Loiseau; Pascal Reynier; Patrick F Chinnery; Agnès Rotig; Valerio Carelli; Christian P Hamel; Michela Rugolo; Guy Lenaers
OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution.
Genome research 2011;21(1):12-20.
2010: Giuseppe Gasparre; Elena Bonora; Giovanni Tallini; Giovanni Romeo
Molecular features of thyroid oncocytic tumors.
Molecular and cellular endocrinology 2010;321(1):67-76.
2010: Anna Maria Porcelli; Anna Ghelli; Claudio Ceccarelli; Martin Lang; Giovanna Cenacchi; Mariantonietta Capristo; Lucia Fiammetta Pennisi; Isabella Morra; Enrica Ciccarelli; Antonio Melcarne; Anna Bartoletti-Stella; Nunzio Salfi; Giovanni Tallini; Andrea Martinuzzi; Valerio Carelli; Marcella Attimonelli; Michela Rugolo; Giovanni Romeo; Giuseppe Gasparre
The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization.
Human molecular genetics 2010;19(6):1019-32.
2009: Giuseppe Gasparre; Luisa Iommarini; Anna Maria Porcelli; Martin Lang; Gian Gaetano Ferri; Ivana Kurelac; Roberta Zuntini; Elisa Mariani; Lucia Fiammetta Pennisi; Ernesto Pasquini; Gianandrea Pasquinelli; Anna Ghelli; Elena Bonora; Claudio Ceccarelli; Michela Rugolo; Nunzio Salfi; Giovanni Romeo; Valerio Carelli
An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells.
Human mutation 2009;30(3):391-6.
2008: Anna Maria Porcelli; Anna Ghelli; Luisa Iommarini; E Mariani; M Hoque; Claudia Zanna; Giuseppe Gasparre; Michela Rugolo
The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I.
Cellular and molecular life sciences : CMLS 2008;65(18):2943-51.
2008: Giuseppe Gasparre; Eric Hervouet; Elodie de Laplanche; Jocelyne Demont; Lucia Fiammetta Pennisi; Marc Colombel; Florence Mège-Lechevallier; Jean-Yves Scoazec; Elena Bonora; Roel Smeets; Jan A M Smeitink; Vladimir Lazar; James Lespinasse; Sophie Giraud; Catherine Godinot; Giovanni Romeo; Hélène Simonnet
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma.
Human molecular genetics 2008;17(7):986-95.
2008: Daniela Lascaro; Stefano Castellana; Giuseppe Gasparre; Giovanni Romeo; Cecilia Saccone; Marcella Attimonelli
The RHNumtS compilation: features and bioinformatics approaches to locate and quantify Human NumtS.
BMC genomics 2008;9():267.
2007: Giuseppe Gasparre; Anna Maria Porcelli; Elena Bonora; Lucia Fiammetta Pennisi; Matteo Toller; Luisa Iommarini; Anna Ghelli; Massimo Moretti; Christine M Betts; Giuseppe Nicola Martinelli; Alberto Rinaldi Ceroni; Francesco Curcio; Valerio Carelli; Michela Rugolo; Giovanni Tallini; Giovanni Romeo
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(21):9001-6.
2006: Elena Bonora; Anna Maria Porcelli; Giuseppe Gasparre; Annalisa Biondi; Anna Ghelli; Valerio Carelli; Alessandra Baracca; Giovanni Tallini; Andrea Martinuzzi; Giorgio Lenaz; Michela Rugolo; Giovanni Romeo
Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III.
Cancer research 2006;66(12):6087-96.
2006: Karmen Stankov; Annalisa Biondi; Marilena D'Aurelio; Giuseppe Gasparre; Anna Falasca; Giovanni Romeo; Giorgio Lenaz
Mitochondrial activities of a cell line derived from thyroid Hürthle cell tumors.
Thyroid : official journal of the American Thyroid Association 2006;16(4):325-31.