Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Nibaldo Inestrosa

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Disorders

Alzheimer Disease

Anatomy

Physiology

Signal Transduction

Genes & Molecular Sequences

Amino Acid Sequence

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Arrázola Macarena S; Varela-Nallar Lorena; Colombres Marcela; Toledo Enrique M; Cruzat Fernando; Pavez Leonardo; Assar Rodrigo; Aravena Andrés; González Mauricio; Montecino Martín; Maass Alejandro; Martínez Servet; Inestrosa Nibaldo C
Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.
Vázquez Mary C; Vargas Lina M; Inestrosa Nibaldo C; Alvarez Alejandra R
c-Abl modulates AICD dependent cellular responses: transcriptional induction and apoptosis.
Farías Ginny G; Alfaro Iván E; Cerpa Waldo; Grabowski Catalina P; Godoy Juan A; Bonansco Christian; Inestrosa Nibaldo C
Wnt-5a/JNK signaling promotes the clustering of PSD-95 in hippocampal neurons.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Nibaldo Inestrosa (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Arrázola Macarena S; Varela-Nallar Lorena; Colombres Marcela; Toledo Enrique M; Cruzat Fernando; Pavez Leonardo; Assar Rodrigo; Aravena Andrés; González Mauricio; Montecino Martín; Maass Alejandro; Martínez Servet; Inestrosa Nibaldo C
Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.
Journal of cellular physiology 2009;221(3):658-67.
2009: Vázquez Mary C; Vargas Lina M; Inestrosa Nibaldo C; Alvarez Alejandra R
c-Abl modulates AICD dependent cellular responses: transcriptional induction and apoptosis.
Journal of cellular physiology 2009;220(1):136-43.
2009: Farías Ginny G; Alfaro Iván E; Cerpa Waldo; Grabowski Catalina P; Godoy Juan A; Bonansco Christian; Inestrosa Nibaldo C
Wnt-5a/JNK signaling promotes the clustering of PSD-95 in hippocampal neurons.
The Journal of biological chemistry 2009;284(23):15857-66.
2009: Suazo Miriam; Hodar Christian; Morgan Carlos; Cerpa Waldo; Cambiazo Verónica; Inestrosa Nibaldo C; Gonzalez Mauricio
Overexpression of amyloid precursor protein increases copper content in HEK293 cells.
Biochemical and biophysical research communications 2009;382(4):740-4.
2008: Rebolledo Daniela L; Minniti Alicia N; Grez Paula M; Fadic Ricardo; Kohn Rebecca; Inestrosa Nibaldo C
Inclusion body myositis: a view from the Caenorhabditis elegans muscle.
Molecular neurobiology 2008;38(2):178-98.
2008: Chacón Marcelo A; Varela-Nallar Lorena; Inestrosa Nibaldo C
Frizzled-1 is involved in the neuroprotective effect of Wnt3a against Abeta oligomers.
Journal of cellular physiology 2008;217(1):215-27.
2008: Simonetta Sergio H; Romanowski Andrés; Minniti Alicia N; Inestrosa Nibaldo C; Golombek Diego A
Circadian stress tolerance in adult Caenorhabditis elegans.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 2008;194(9):821-8.
2008: Dinamarca Margarita C; Arrázola Macarena; Toledo Enrique; Cerpa Waldo F; Hancke Juan; Inestrosa Nibaldo C
Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice.
Chemico-biological interactions 2008;175(1-3):142-9.
2008: Cancino Gonzalo I; Toledo Enrique M; Leal Nancy R; Hernandez Diego E; Yévenes L Fernanda; Inestrosa Nibaldo C; Alvarez Alejandra R
STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's beta-amyloid deposits.
Brain : a journal of neurology 2008;131(Pt 9):2425-42.
2008: Colombres Marcela; Henríquez Juan Pablo; Reig Germán F; Scheu Jessica; Calderón Rosario; Alvarez Alejandra; Brandan Enrique; Inestrosa Nibaldo C
Heparin activates Wnt signaling for neuronal morphogenesis.
Journal of cellular physiology 2008;216(3):805-15.
2008: Cerpa Waldo; Dinamarca Margarita C; Inestrosa Nibaldo C
Structure-function implications in Alzheimer's disease: effect of Abeta oligomers at central synapses.
Current Alzheimer research 2008;5(3):233-43.
2008: Inestrosa Nibaldo C; Dinamarca Margarita C; Alvarez Alejandra
Amyloid-cholinesterase interactions. Implications for Alzheimer's disease.
The FEBS journal 2008;275(4):625-32.
2008: Cerpa Waldo; Godoy Juan A; Alfaro Iván; Farías Ginny G; Metcalfe María J; Fuentealba Rodrigo; Bonansco Christian; Inestrosa Nibaldo C
Wnt-7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons.
The Journal of biological chemistry 2008;283(9):5918-27.
2008: Inestrosa Nibaldo C; Toledo Enrique M
The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease.
Molecular neurodegeneration 2008;3():9.
2008: Dinamarca Margarita C; Colombres Marcela; Cerpa Waldo; Bonansco Christian; Inestrosa Nibaldo C
Beta-amyloid oligomers affect the structure and function of the postsynaptic region: role of the Wnt signaling pathway.
Neuro-degenerative diseases 2008;5(3-4):149-52.
2007: Fuenzalida Karen; Quintanilla Rodrigo; Ramos Patricio; Piderit Daniela; Fuentealba Rodrigo A; Martinez Gabriela; Inestrosa Nibaldo C; Bronfman Miguel
Peroxisome proliferator-activated receptor gamma up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis.
The Journal of biological chemistry 2007;282(51):37006-15.
2007: Farías Ginny G; Vallés Ana S; Colombres Marcela; Godoy Juan A; Toledo Enrique M; Lukas Ronald J; Barrantes Francisco J; Inestrosa Nibaldo C
Wnt-7a induces presynaptic colocalization of alpha 7-nicotinic acetylcholine receptors and adenomatous polyposis coli in hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(20):5313-25.
2007: Inestrosa Nibaldo C; Varela-Nallar Lorena; Grabowski Catalina P; Colombres Marcela
Synaptotoxicity in Alzheimer's disease: the Wnt signaling pathway as a molecular target.
IUBMB life 2007;59(4-5):316-21.
2007: Fuentealba Rodrigo A; Barría Maria Ines; Lee Jiyeon; Cam Judy; Araya Claudia; Escudero Claudia A; Inestrosa Nibaldo C; Bronfman Francisca C; Bu Guojun; Marzolo Maria-Paz
ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity.
Molecular neurodegeneration 2007;2():14.
2006: Dinamarca M C; Cerpa W; Garrido J; Hancke J L; Inestrosa N C
Hyperforin prevents beta-amyloid neurotoxicity and spatial memory impairments by disaggregation of Alzheimer's amyloid-beta-deposits.
Molecular psychiatry 2006;11(11):1032-48.
2006: Varela-Nallar Lorena; Toledo Enrique M; Larrondo Luis F; Cabral Ana L B; Martins Vilma R; Inestrosa Nibaldo C
Induction of cellular prion protein gene expression by copper in neurons.
American journal of physiology. Cell physiology 2006;290(1):C271-81.
2006: Varela-Nallar Lorena; González Alfonso; Inestrosa Nibaldo C
Role of copper in prion diseases: deleterious or beneficial?
Current pharmaceutical design 2006;12(20):2587-95.
2006: Varela-Nallar Lorena; Toledo Enrique M; Chacón Marcelo A; Inestrosa Nibaldo C
The functional links between prion protein and copper.
Biological research 2006;39(1):39-44.
2005: Santos Manuel J; Quintanilla Rodrigo A; Toro Andrés; Grandy Rodrigo; Dinamarca Margarita C; Godoy Juan A; Inestrosa Nibaldo C
Peroxisomal proliferation protects from beta-amyloid neurodegeneration.
The Journal of biological chemistry 2005;280(49):41057-68.
2005: Inestrosa Nibaldo C; Cerpa Waldo; Varela-Nallar Lorena
Copper brain homeostasis: role of amyloid precursor protein and prion protein.
IUBMB life 2005;57(9):645-50.
2005: Cuitino Loreto; Matute Ricardo; Retamal Claudio; Bu Guojun; Inestrosa Nibaldo C; Marzolo María-Paz
ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.
Traffic (Copenhagen, Denmark) 2005;6(9):820-38.
2005: Cerpa Waldo; Varela-Nallar Lorena; Reyes Ariel E; Minniti Alicia N; Inestrosa Nibaldo C
Is there a role for copper in neurodegenerative diseases?
Molecular aspects of medicine 2005;26(4-5):405-20.
2005: Inestrosa Nibaldo C; Alvarez Alejandra; Dinamarca Margarita C; Pérez-Acle Tomás; Colombres Marcela
Acetylcholinesterase-amyloid-beta-peptide interaction: effect of Congo Red and the role of the Wnt pathway.
Current Alzheimer research 2005;2(3):301-6.
2005: Inestrosa Nibaldo C; Reyes Ariel E; Chacón Marcelo A; Cerpa Waldo; Villalón Aldo; Montiel Juan; Merabachvili Genevieve; Aldunate Rebeca; Bozinovic Francisco; Aboitiz Francisco
Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu.
Neurobiology of aging 2005;26(7):1023-8.
2005: Inestrosa Nibaldo C; Godoy Juan A; Quintanilla Rodrigo A; Koenig Cecilia S; Bronfman Miguel
Peroxisome proliferator-activated receptor gamma is expressed in hippocampal neurons and its activation prevents beta-amyloid neurodegeneration: role of Wnt signaling.
Experimental cell research 2005;304(1):91-104.
2005: Quintanilla Rodrigo A; Muñoz Francisco J; Metcalfe Maria J; Hitschfeld Maureen; Olivares Gonzalo; Godoy Juan A; Inestrosa Nibaldo C
Trolox and 17beta-estradiol protect against amyloid beta-peptide neurotoxicity by a mechanism that involves modulation of the Wnt signaling pathway.
The Journal of biological chemistry 2005;280(12):11615-25.
2005: Farías Ginny G; Godoy Juan A; Vázquez Mary C; Adani Rellie; Meshulam Haim; Avila Jesús; Amitai Gabi; Inestrosa Nibaldo C
The anti-inflammatory and cholinesterase inhibitor bifunctional compound IBU-PO protects from beta-amyloid neurotoxicity by acting on Wnt signaling components.
Neurobiology of disease 2005;18(1):176-83.
2005: Inestrosa Nibaldo C; Sagal Juan Paulo; Colombres Marcela
Acetylcholinesterase interaction with Alzheimer amyloid beta.
Sub-cellular biochemistry 2005;38():299-317.
2005: von Bernhardi Rommy; Alarcón Rodrigo; Mezzano Diego; Fuentes Patricio; Inestrosa Nibaldo C
Blood cells cholinesterase activity in early stage Alzheimer's disease and vascular dementia.
Dementia and geriatric cognitive disorders 2005;19(4):204-12.
2004: Morgan Carlos; Colombres Marcela; Nuñez Marco Tulio; Inestrosa Nibaldo C
Structure and function of amyloid in Alzheimer's disease.
Progress in neurobiology 2004;74(6):323-49.
2004: Fuentealba Rodrigo A; Farias Ginny; Scheu Jessica; Bronfman Miguel; Marzolo María Paz; Inestrosa Nibaldo C
Signal transduction during amyloid-beta-peptide neurotoxicity: role in Alzheimer disease.
Brain research. Brain research reviews 2004;47(1-3):275-89.
2004: Aldunate Rebeca; Casar Juan Carlos; Brandan Enrique; Inestrosa Nibaldo C
Structural and functional organization of synaptic acetylcholinesterase.
Brain research. Brain research reviews 2004;47(1-3):96-104.
2004: Inestrosa Nibaldo C; Urra Soledad; Colombres Marcela
Acetylcholinesterase (AChE)--amyloid-beta-peptide complexes in Alzheimer's disease. the Wnt signaling pathway.
Current Alzheimer research 2004;1(4):249-54.
2004: Farías Ginny G; Godoy Juan A; Hernández Félix; Avila Jesús; Fisher Abraham; Inestrosa Nibaldo C
M1 muscarinic receptor activation protects neurons from beta-amyloid toxicity. A role for Wnt signaling pathway.
Neurobiology of disease 2004;17(2):337-48.
2004: Cerpa Waldo F; Barría María I; Chacón Marcelo A; Suazo Miriam; González Mauricio; Opazo Carlos; Bush Ashley I; Inestrosa Nibaldo C
The N-terminal copper-binding domain of the amyloid precursor protein protects against Cu2+ neurotoxicity in vivo.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(14):1701-3.
2004: Chacón M A; Barría M I; Soto C; Inestrosa N C
Beta-sheet breaker peptide prevents Abeta-induced spatial memory impairments with partial reduction of amyloid deposits.
Molecular psychiatry 2004;9(10):953-61.
2004: Alvarez Alejandra R; Godoy Juan A; Mullendorff Karin; Olivares Gonzalo H; Bronfman Miguel; Inestrosa Nibaldo C
Wnt-3a overcomes beta-amyloid toxicity in rat hippocampal neurons.
Experimental cell research 2004;297(1):186-96.
2004: Reyes Ariel E; Chacón Marcelo A; Dinamarca Margarita C; Cerpa Waldo; Morgan Carlos; Inestrosa Nibaldo C
Acetylcholinesterase-Abeta complexes are more toxic than Abeta fibrils in rat hippocampus: effect on rat beta-amyloid aggregation, laminin expression, reactive astrocytosis, and neuronal cell loss.
The American journal of pathology 2004;164(6):2163-74.
2004: Doss-Pepe Ellen; Deprez Paola; Silva Teresita; Inestrosa Nibaldo C; Kirkpatrick Alan; Ramshaw John A M; Brodsky Barbara
Stepwise construction of triple-helical heparin binding sites using peptide models.
Biochimica et biophysica acta 2004;1698(2):187-95.
2004: Casar Juan Carlos; Cabello-Verrugio Claudio; Olguin Hugo; Aldunate Rebeca; Inestrosa Nibaldo C; Brandan Enrique
Heparan sulfate proteoglycans are increased during skeletal muscle regeneration: requirement of syndecan-3 for successful fiber formation.
Journal of cell science 2004;117(Pt 1):73-84.
2004: Colombres Marcela; Sagal Juan Paulo; Inestrosa Nibaldo C
An overview of the current and novel drugs for Alzheimer's disease with particular reference to anti-cholinesterase compounds.
Current pharmaceutical design 2004;10(25):3121-30.
2003: von Bernhardi Rommy; Ramírez Gigliola; De Ferrari Giancarlo V; Inestrosa Nibaldo C
Acetylcholinesterase induces the expression of the beta-amyloid precursor protein in glia and activates glial cells in culture.
Neurobiology of disease 2003;14(3):447-57.
2003: Chacón M A; Barría M I; Lorca R; Huidobro-Toro J P; Inestrosa N C
A human prion protein peptide (PrP(59-91)) protects against copper neurotoxicity.
Molecular psychiatry 2003;8(10):853-62, 835.
2003: Chacón Marcelo A; Reyes Ariel E; Inestrosa Nibaldo C
Acetylcholinesterase induces neuronal cell loss, astrocyte hypertrophy and behavioral deficits in mammalian hippocampus.
Journal of neurochemistry 2003;87(1):195-204.
2003: Deprez Paola; Inestrosa Nibaldo C; Krejci Eric
Two different heparin-binding domains in the triple-helical domain of ColQ, the collagen tail subunit of synaptic acetylcholinesterase.
The Journal of biological chemistry 2003;278(26):23233-42.
2003: Roth Alejandro D; Leisewitz Andrea V; Jung Juan E; Cassina Patricia; Barbeito Luis; Inestrosa Nibaldo C; Bronfman Miguel
PPAR gamma activators induce growth arrest and process extension in B12 oligodendrocyte-like cells and terminal differentiation of cultured oligodendrocytes.
Journal of neuroscience research 2003;72(4):425-35.
2003: Lorca Ramón A; Chacón Marcelo; Barría María Inés; Inestrosa Nibaldo C; Huidobro-Toro J Pablo
The human prion octarepeat fragment prevents and reverses the inhibitory action of copper in the P2X4 receptor without modifying the zinc action.
Journal of neurochemistry 2003;85(3):709-16.
2003: Leisewitz Andrea V; Jung Juan E; Perez-Alzola Patricia; Fuenzalida Karen M; Roth Alejandro; Inestrosa Nibaldo C; Bronfman Miguel
Ethanol specifically decreases peroxisome proliferator activated receptor beta in B12 oligodendrocyte-like cells.
Journal of neurochemistry 2003;85(1):135-41.
2003: Opazo Carlos; Barría María Inés; Ruiz Francisca H; Inestrosa Nibaldo C
Copper reduction by copper binding proteins and its relation to neurodegenerative diseases.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2003;16(1):91-8.
2003: De Ferrari G V; Chacón M A; Barría M I; Garrido J L; Godoy J A; Olivares G; Reyes A E; Alvarez A; Bronfman M; Inestrosa N C
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils.
Molecular psychiatry 2003;8(2):195-208.
2003: Inestrosa Nibaldo C
[Dr. Joaquín Luco Valenzuela. 1913-2002]
Biological research 2003;36(2):143-6.
2002: Garrido José L; Godoy Juan A; Alvarez Alejandra; Bronfman Miguel; Inestrosa Nibaldo C
Protein kinase C inhibits amyloid beta peptide neurotoxicity by acting on members of the Wnt pathway.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(14):1982-4.
2002: Inestrosa Nibaldo; De Ferrari Giancarlo V; Garrido José L; Alvarez Alejandra; Olivares Gonzalo H; Barría María I; Bronfman Miguel; Chacón Marcelo A
Wnt signaling involvement in beta-amyloid-dependent neurodegeneration.
Neurochemistry international 2002;41(5):341-4.
2002: Opazo Carlos; Huang Xudong; Cherny Robert A; Moir Robert D; Roher Alex E; White Anthony R; Cappai Roberto; Masters Colin L; Tanzi Rudolph E; Inestrosa Nibaldo C; Bush Ashley I
Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).
The Journal of biological chemistry 2002;277(43):40302-8.
2002: Morgan Carlos; Bugueño Manuel P; Garrido Jorge; Inestrosa Nibaldo C
Laminin affects polymerization, depolymerization and neurotoxicity of Abeta peptide.
Peptides 2002;23(7):1229-40.
2002: Muñoz Francisco J; Opazo Carlos; Gil-Gómez Gabriel; Tapia Gladys; Fernández Virginia; Valverde Miguel A; Inestrosa Nibaldo C
Vitamin E but not 17beta-estradiol protects against vascular toxicity induced by beta-amyloid wild type and the Dutch amyloid variant.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(8):3081-9.
2001: De Ferrari G V; Canales M A; Shin I; Weiner L M; Silman I; Inestrosa N C
A structural motif of acetylcholinesterase that promotes amyloid beta-peptide fibril formation.
Biochemistry 2001;40(35):10447-57.
2001: De Ferrari G V; Mallender W D; Inestrosa N C; Rosenberry T L
Thioflavin T is a fluorescent probe of the acetylcholinesterase peripheral site that reveals conformational interactions between the peripheral and acylation sites.
The Journal of biological chemistry 2001;276(26):23282-7.
2000: Doss-Pepe E; Deprez P; Inestrosa N C; Brodsky B
Interaction of collagen-like peptide models of asymmetric acetylcholinesterase with glycosaminoglycans: spectroscopic studies of conformational changes and stability.
Biochemistry 2000;39(48):14884-92.
2000: Miranda S; Opazo C; Larrondo L F; Muñoz F J; Ruiz F; Leighton F; Inestrosa N C
The role of oxidative stress in the toxicity induced by amyloid beta-peptide in Alzheimer's disease.
Progress in neurobiology 2000;62(6):633-48.
2000: De Ferrari G V; Inestrosa N C
Wnt signaling function in Alzheimer's disease.
Brain research. Brain research reviews 2000;33(1):1-12.
2000: Deprez P; Doss-Pepe E; Brodsky B; Inestrosa N C
Interaction of the collagen-like tail of asymmetric acetylcholinesterase with heparin depends on triple-helical conformation, sequence and stability.
The Biochemical journal 2000;350 Pt 1():283-90.
2000: Marzolo M P; von Bernhardi R; Bu G; Inestrosa N C
Expression of alpha(2)-macroglobulin receptor/low density lipoprotein receptor-related protein (LRP) in rat microglial cells.
Journal of neuroscience research 2000;60(3):401-11.
2000: Ruiz F H; Silva E; Inestrosa N C
The N-terminal tandem repeat region of human prion protein reduces copper: role of tryptophan residues.
Biochemical and biophysical research communications 2000;269(2):491-5.
2000: Opazo C; Ruiz F H; Inestrosa N C
Amyloid-beta-peptide reduces copper(II) to copper(I) independent of its aggregation state.
Biological research 2000;33(2):125-31.
2000: Inestrosa N C; Alvarez A; Godoy J; Reyes A; De Ferrari G V
Acetylcholinesterase-amyloid-beta-peptide interaction and Wnt signaling involvement in Abeta neurotoxicity.
Acta neurologica Scandinavica. Supplementum 2000;176():53-9.
1999: Muñoz F J; Aldunate R; Inestrosa N C
Peripheral binding site is involved in the neurotrophic activity of acetylcholinesterase.
Neuroreport 1999;10(17):3621-5.
1999: Marzolo M P; von Bernhardi R; Inestrosa N C
Mannose receptor is present in a functional state in rat microglial cells.
Journal of neuroscience research 1999;58(3):387-95.
1999: Ruiz F H; González M; Bodini M; Opazo C; Inestrosa N C
Cysteine 144 is a key residue in the copper reduction by the beta-amyloid precursor protein.
Journal of neurochemistry 1999;73(3):1288-92.
1999: Calderón F H; Bonnefont A; Muñoz F J; Fernández V; Videla L A; Inestrosa N C
PC12 and neuro 2a cells have different susceptibilities to acetylcholinesterase-amyloid complexes, amyloid25-35 fragment, glutamate, and hydrogen peroxide.
Journal of neuroscience research 1999;56(6):620-31.
1999: Muñoz F J; Inestrosa N C
Neurotoxicity of acetylcholinesterase amyloid beta-peptide aggregates is dependent on the type of Abeta peptide and the AChE concentration present in the complexes.
FEBS letters 1999;450(3):205-9.
1998: Bonnefont A B; Muñoz F J; Inestrosa N C
Estrogen protects neuronal cells from the cytotoxicity induced by acetylcholinesterase-amyloid complexes.
FEBS letters 1998;441(2):220-4.
1998: Inestrosa N C; Alarcón R
Molecular interactions of acetylcholinesterase with senile plaques.
Journal of physiology, Paris 1998;92(5-6):341-4.
1998: Casanueva O I; Deprez P; García-Huidobro T; Inestrosa N C
At least two receptors of asymmetric acetylcholinesterase are present at the synaptic basal lamina of Torpedo electric organ.
Biochemical and biophysical research communications 1998;250(2):312-7.
1998: Calderón F H; von Bernhardi R; De Ferrari G; Luza S; Aldunate R; Inestrosa N C
Toxic effects of acetylcholinesterase on neuronal and glial-like cells in vitro.
Molecular psychiatry 1998;3(3):247-55.
1998: De Ferrari G V; von Bernhardi R; Calderón F H; Luza S C; Inestrosa N C
Responses induced by tacrine in neuronal and non-neuronal cell lines.
Journal of neuroscience research 1998;52(4):435-44.
1998: Alvarez A; Alarcón R; Opazo C; Campos E O; Muñoz F J; Calderón F H; Dajas F; Gentry M K; Doctor B P; De Mello F G; Inestrosa N C
Stable complexes involving acetylcholinesterase and amyloid-beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(9):3213-23.
1998: Moreno R D; Campos F O; Dajas F; Inestrosa N C
Developmental regulation of mouse brain monomeric acetylcholinesterase.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1998;16(2):123-34.
1998: Bronfman F C; Alvarez A; Morgan C; Inestrosa N C
Laminin blocks the assembly of wild-type A beta and the Dutch variant peptide into Alzheimer's fibrils.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1998;5(1):16-23.
1998: Campos E O; Alvarez A; Inestrosa N C
Brain acetylcholinesterase promotes amyloid-beta-peptide aggregation but does not hydrolyze amyloid precursor protein peptides.
Neurochemical research 1998;23(2):135-40.
1998: Casanueva O I; García-Huidobro T; Campos E O; Aldunate R; Garrido J; Inestrosa N C
A major portion of synaptic basal lamina acetylcholinesterase is detached by high salt- and heparin-containing buffers from rat diaphragm muscle and Torpedo electric organ.
The Journal of biological chemistry 1998;273(7):4258-65.
1998: Opazo C; Inestrosa N C
Crosslinking of amyloid-beta peptide to brain acetylcholinesterase.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1998;33(1):39-49.
1998: Inestrosa N C; Marzolo M P; Bonnefont A B
Cellular and molecular basis of estrogen's neuroprotection. Potential relevance for Alzheimer's disease.
Molecular neurobiology 1998;17(1-3):73-86.
1997: Alvarez A; Opazo C; Alarcón R; Garrido J; Inestrosa N C
Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils.
Journal of molecular biology 1997;272(3):348-61.
1997: Reyes A E; Perez D R; Alvarez A; Garrido J; Gentry M K; Doctor B P; Inestrosa N C
A monoclonal antibody against acetylcholinesterase inhibits the formation of amyloid fibrils induced by the enzyme.
Biochemical and biophysical research communications 1997;232(3):652-5.
1996: Inestrosa N C; Alvarez A; Calderón F
Acetylcholinesterase is a senile plaque component that promotes assembly of amyloid beta-peptide into Alzheimer's filaments.
Molecular psychiatry 1996;1(5):359-61.
1996: Bronfman F C; Garrido J; Alvarez A; Morgan C; Inestrosa N C
Laminin inhibits amyloid-beta-peptide fibrillation.
Neuroscience letters 1996;218(3):201-3.
1996: Bronfman F C; Fernandez H L; Inestrosa N C
Amyloid precursor protein fragment and acetylcholinesterase increase with cell confluence and differentiation in a neuronal cell line.
Experimental cell research 1996;229(1):93-9.
1996: Moreno R D; Inestrosa N C; Culwell A R; Alvarez J
Sprouting and abnormal contacts of nonmedullated axons, and deposition of extracellular material induced by the amyloid precursor protein (APP) and other protease inhibitors.
Brain research 1996;718(1-2):13-24.
1996: Fernandez H L; Moreno R D; Inestrosa N C
Tetrameric (G4) acetylcholinesterase: structure, localization, and physiological regulation.
Journal of neurochemistry 1996;66(4):1335-46.
1996: Inestrosa N C; Alvarez A; Pérez C A; Moreno R D; Vicente M; Linker C; Casanueva O I; Soto C; Garrido J
Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.
Neuron 1996;16(4):881-91.
1996: Inestrosa N C; Sunkel C E; Arriagada J; Garrido J; Godoy-Herrera R
Abnormal development of the locomotor activity in yellow larvae of Drosophila: a cuticular defect?
Genetica 1996;97(2):205-10.
1996: Bronfman F C; Soto C; Tapia L; Tapia V; Inestrosa N C
Extracellular matrix regulates the amount of the beta-amyloid precursor protein and its amyloidogenic fragments.
Journal of cellular physiology 1996;166(2):360-9.
1995: Alvarez A; Bronfman F; Pérez C A; Vicente M; Garrido J; Inestrosa N C
Acetylcholinesterase, a senile plaque component, affects the fibrillogenesis of amyloid-beta-peptides.
Neuroscience letters 1995;201(1):49-52.
1995: Deprez P N; Signorelli J; Inestrosa N C
Effect of protamine on the solubilization of collagen-tailed acetylcholinesterase: potential heparin-binding consensus sequences in the tail of the enzyme.
Biochimica et biophysica acta 1995;1252(1):53-8.
1995: Deprez P N; Inestrosa N C
Two heparin-binding domains are present on the collagenic tail of asymmetric acetylcholinesterase.
The Journal of biological chemistry 1995;270(19):11043-6.
1995: Soto C; Castaño E M; Frangione B; Inestrosa N C
The alpha-helical to beta-strand transition in the amino-terminal fragment of the amyloid beta-peptide modulates amyloid formation.
The Journal of biological chemistry 1995;270(7):3063-7.
1995: Alvarez J; Moreno R D; Inestrosa N C
Mitosis of Schwann cells and demyelination are induced by the amyloid precursor protein and other protease inhibitors in the rat sciatic nerve.
The European journal of neuroscience 1995;7(1):152-9.
1995: Tapia M; Inestrosa N C; Alvarez J
Early axonal regeneration: repression by Schwann cells and a protease?
Experimental neurology 1995;131(1):124-32.
1994: Inestrosa N C; Pérez C A; Simpfendorfer R W
Sensitivity of acetylcholinesterase molecular forms to inhibition by high MgCl2 concentration.
Biochimica et biophysica acta 1994;1208(2):286-93.
1994: Soto C; Brañes M C; Alvarez J; Inestrosa N C
Structural determinants of the Alzheimer's amyloid beta-peptide.
Journal of neurochemistry 1994;63(4):1191-8.
1994: Inestrosa N C; Moreno R D; Fuentes M E
Monomeric amphiphilic forms of acetylcholinesterase appear early during brain development and may correspond to biosynthetic precursors of the amphiphilic G4 forms.
Neuroscience letters 1994;173(1-2):155-8.
1994: Inestrosa N C; Alarcón R; Arriagada J; Donoso A; Alvarez J; Campos E O
Blood markers in Alzheimer disease: subnormal acetylcholinesterase and butyrylcholinesterase in lymphocytes and erythrocytes.
Journal of the neurological sciences 1994;122(1):1-5.
1993: Inestrosa N C; Alarcón R; Arriagada J; Donoso A; Alvarez J
Platelet of Alzheimer patients: increased counts and subnormal uptake and accumulation of [14C]5-hydroxytryptamine.
Neuroscience letters 1993;163(1):8-10.
1993: Krauss R Y; Alvarez J; Inestrosa N C
A neurofilament polypeptide and the glial fibrillary acidic protein share common epitopes in the variable region.
Neuroscience letters 1993;161(2):137-40.
1993: Brandan E; Inestrosa N C
Extracellular matrix components and amyloid in neuritic plaques of Alzheimer's disease.
General pharmacology 1993;24(5):1063-8.
1993: Gonzalez R A; Campos E O; Karmelic C; Moran S; Inestrosa N C
Acetylcholinesterase changes in hearts with sinus rhythm and atrial fibrillation.
General pharmacology 1993;24(1):111-4.
1992: Brandan E; González M; Inestrosa N C; Tremblay C; Urrea R
A high molecular weight proteoglycan is differentially expressed during development of the mollusc Concholepas concholepas (Mollusca; Gastropoda; Muricidae).
The Journal of experimental zoology 1992;264(4):363-71.
1992: Alvarez J; Moreno R D; Llanos O; Inestrosa N C; Brandan E; Colby T; Esch F S
Axonal sprouting induced in the sciatic nerve by the amyloid precursor protein (APP) and other antiproteases.
Neuroscience letters 1992;144(1-2):130-4.
1992: Gonzalez R; Urrea R; Gonzalez M; Inestrosa N C; Brandan E
Isolation of proteoglycans synthesized by rat heart: evidence for the presence of several distinct forms.
General pharmacology 1992;23(2):249-55.
1991: Moya M A; Fuentes M E; Inestrosa N C
A comparison of the Xenopus laevis oocyte acetylcholinesterase with the muscle and brain enzyme suggests variations at the post-translational level.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1991;98(2-3):299-305.
1991: González R; Campos E O; Morán S; Inestrosa N C
Characterization of acetylcholinesterase from human heart auricles: evidence for the presence of a G-form sensitive to phosphatidylinositol-specific phospholipase c.
General pharmacology 1991;22(1):107-10.
1990: Fadic R; Brandan E; Inestrosa N C
Motor nerve regulates muscle extracellular matrix proteoglycan expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(11):3516-23.
1990: Inestrosa N C; Perelman A
Association of acetylcholinesterase with the cell surface.
The Journal of membrane biology 1990;118(1):1-9.
1990: von Bernhardi R; Inestrosa N C
Dermatan sulfate and de-sulfated heparin solubilized collagen-tailed acetylcholinesterase from the rat neuromuscular junction.
Brain research 1990;529(1-2):91-5.
1990: Inestrosa N C; Labarca R; Perelman A; Campos E O; Araneda R; González M; Brandan E; Sánchez J P; González-Plaza R
[Biotechnological aspects in "loco" larvae]
Archivos de biología y medicina experimentales 1990;23(2):179-86.
1990: Perelman A; Abeijon C; Hirschberg C B; Inestrosa N C; Brandan E
Differential association and distribution of acetyl- and butyrylcholinesterases within rat liver subcellular organelles.
The Journal of biological chemistry 1990;265(1):214-20.
1990: von Bernhardi R; Ayal H; Inestrosa N C
Carrageenans solubilize asymmetric acetylcholinesterase from nicotinic cholinergic synapses.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1990;96(1):77-81.
1989: Prieto A L; Fuentes M E; Arqueros L; Inestrosa N C
Phosphatidylinositol-specific phospholipase C solubilized G2 acetylcholinesterase from plasma membranes of chromaffin cells.
Journal of neuroscience research 1989;24(2):169-73.
1989: Perelman A; Inestrosa N C
A simple assay to estimate the acetylcholinesterase molecular forms in crude extracts of rat skeletal muscle.
Analytical biochemistry 1989;180(2):227-30.
1989: Fadic R; Inestrosa N C
Nerve regulation of class I and class II-asymmetric forms of acetylcholinesterase in rat skeletal muscles.
Journal of neuroscience research 1989;22(4):449-55.
1989: Allende M L; Krauss R Y; Tremblay C; Alvarez J; Inestrosa N C
Anti-200 kDa neurofilament antibody cross-reacts with microtubule-associated protein-2 (MAP-2).
Journal of neuroscience research 1989;22(2):130-3.
1988: Inestrosa N C; Cross D
Expression of size-selected messenger RNA encoding the brain and adrenal gland angiotensin-II receptor in Xenopus laevis oocytes.
Archivos de biología y medicina experimentales 1988;21(3-4):423-8.
1988: Fuentes M E; Rosenberry T L; Inestrosa N C
A 13 kDa fragment is responsible for the hydrophobic aggregation of brain G4 acetylcholinesterase.
The Biochemical journal 1988;256(3):1047-50.
1988: Fadic R; Soza M A; Inestrosa N C
Changes in contralateral synaptic acetylcholinesterase following motor nerve section in rats.
Neuroscience letters 1988;90(1-2):229-33.
1988: Fuentes M E; Inestrosa N C
Characterization of a tetrameric G4 form of acetylcholinesterase from bovine brain: a comparison with the dimeric G2 form of the electric organ.
Molecular and cellular biochemistry 1988;81(1):53-64.
1988: Inestrosa N C; Alvarez J
Axons grow in the aging rat but fast transport and acetylcholinesterase content remain unchanged.
Brain research 1988;441(1-2):331-8.
1987: Cross D; Cifuentes F; Huidobro-Toro J P; Vío C P; Inestrosa N C
Synthesis and expression of functional angiotensin II receptors in Xenopus oocytes injected with rat brain mRNA.
Brain research 1987;388(3):268-70.
1987: Inestrosa N C; Sunkel C; Arriagada J
The sensory projections of Drosophila mutants which show abnormal wing formation or flying behavior.
Brain research 1987;416(2):248-56.
1987: Cross D; Allende M L; Krauss R Y; Fuentes M E; Kaltwasser G; Alvarez J; Inestrosa N C
Biosynthesis of the neurofilament heavy subunit in Xenopus oocytes microinjected with rat brain poly(A)+ RNA.
Molecular biology reports 1987;12(4):265-71.
1987: Ruiz G; Flores O G; González-Plaza R; Inestrosa N C
Effect of phenytoin on cytoskeletal protein phosphorylation and neuronal structure in the rat sensory cortex.
Journal of neuroscience research 1987;18(3):466-72.
1987: Inestrosa N C; Nader H B; Garrido J; Sampaio L O; Brandan E; Dietrich C P
Glycosaminoglycan composition of electric organ basement membranes.
Journal of neuroscience research 1987;17(3):256-64.
1985: Brandan E; Maldonado M; Garrido J; Inestrosa N C
Anchorage of collagen-tailed acetylcholinesterase to the extracellular matrix is mediated by heparan sulfate proteoglycans.
The Journal of cell biology 1985;101(3):985-92.
1984: Méndez B; Garrido J; Maldonado M; Jaksic F M; Inestrosa N C
The electric organ of Discopyge tschudii: its innervated face and the biology of acetylcholinesterase.
Cellular and molecular neurobiology 1984;4(2):125-42.
1983: Inestrosa N C; Méndez B
The A12 acetylcholinesterase and polypeptide composition of electric organ basal lamina of Electrophorus and some Torpedinae fishes.
Cell biochemistry and function 1983;1(1):41-8.
1976: Inestrosa N C; Fernandez H L; Garrido J
Actin-like filaments in synaptosomes detected by heavy meromyosin binding.
Neuroscience letters 1976;2(4):217-21.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Nibaldo Inestrosa

Research Profile (preview)

Chemicals & Drugs

Living Beings

Disorders

Anatomy

Physiology

Genes & Molecular Sequences

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Nibaldo Inestrosa (preview)

All Publications