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Julja Burchard

Research Profile

Chemicals & Drugs

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Oligonucleotide Array Sequence Analysis

Physiology

Procedures

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Mouse

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RNA Interference

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Publications

TOP 3
Morten Lindow; Saraswathy Nochur; Joel Parry; Donald Riley; James D Thompson; Hans-Peter Vornlocher; Laurence O Whiteley; Husam Younis; Steven Bartz; Julja Burchard; Nicolay Ferrari; Scott P Henry; Joanne Kamens; Douglas J Kornbrust; Arthur A Levin
Assessing unintended hybridization-induced biological effects of oligonucleotides.
Eugen Buehler; Julja Burchard; Aly A Khan; Shane Marine; Misha Rajaram; Amit Bahl; Marc Ferrer
siRNA off-target effects in genome-wide screens identify signaling pathway members.
John M Luk; Ulrike Philippar; Ronnie T Poon; Peter M Shaw; Felix H Shek; Daniel G Tenen; Kwong F Wong; Chunsheng Zhang; Julja Burchard; Carolyn A Buser; Michele A Cleary; Hongyue Dai; Sheung-Tat Fan; Irena Ivanovska; Chuen Neng Lee; Nikki P Y Lee; Angela M Liu; Mao Mao
DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival.

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All Publications

2012: Morten Lindow; Saraswathy Nochur; Joel Parry; Donald Riley; James D Thompson; Hans-Peter Vornlocher; Laurence O Whiteley; Husam Younis; Steven Bartz; Julja Burchard; Nicolay Ferrari; Scott P Henry; Joanne Kamens; Douglas J Kornbrust; Arthur A Levin
Assessing unintended hybridization-induced biological effects of oligonucleotides.
Nature biotechnology 2012;30(10):920-3.
2012: Eugen Buehler; Julja Burchard; Aly A Khan; Shane Marine; Misha Rajaram; Amit Bahl; Marc Ferrer
siRNA off-target effects in genome-wide screens identify signaling pathway members.
Scientific reports 2012;2():428.
2011: John M Luk; Ulrike Philippar; Ronnie T Poon; Peter M Shaw; Felix H Shek; Daniel G Tenen; Kwong F Wong; Chunsheng Zhang; Julja Burchard; Carolyn A Buser; Michele A Cleary; Hongyue Dai; Sheung-Tat Fan; Irena Ivanovska; Chuen Neng Lee; Nikki P Y Lee; Angela M Liu; Mao Mao
DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival.
The Journal of biological chemistry 2011;286(35):30706-13.
2011: Myra L Wang; Kristin L Robinson; Ryan Walsh; Steven Bartz; Julja Burchard; Michele Cleary; Denise A Galloway; Carla Grandori
Gene expression signature of c-MYC-immortalized human fibroblasts reveals loss of growth inhibitory response to TGFβ.
Cell cycle (Georgetown, Tex.) 2011;10(15):2540-8.
2011: Jie Wei; Jeffrey Jones; Jing Kang; Ananda Card; Michael Krimm; Paula Hancock; Yi Pei; Brandon Ason; Elmer Payson; Natalya Dubinina; Mark Cancilla; Mark Stroh; Julja Burchard; Alan B Sachs; Jerome H Hochman; W Michael Flanagan; Nelly A Kuklin
RNA-induced silencing complex-bound small interfering RNA is a determinant of RNA interference-mediated gene silencing in mice.
Molecular pharmacology 2011;79(6):953-63.
2011: Angela M Liu; Chunsheng Zhang; Julja Burchard; S T Fan; Kwong-Fai Wong; Hongyue Dai; Ronnie T Poon; John M Luk
Global regulation on microRNA in hepatitis B virus-associated hepatocellular carcinoma.
Omics : a journal of integrative biology 2011;15(3):187-91.
2010: Julja Burchard; Chunsheng Zhang; Angela M Liu; Ronnie T P Poon; Nikki P Y Lee; Kwong-Fai Wong; Pak C Sham; Brian Y Lam; Mark D Ferguson; George Tokiwa; Ryan Smith; Brendan Leeson; Rebecca Beard; John R Lamb; Lee Lim; Mao Mao; Hongyue Dai; John Luk
microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma.
Molecular systems biology 2010;6():402.
2009: Zhan Zhang; Hong Sun; Hongyue Dai; Ryan M Walsh; Maki Imakura; Janell Schelter; Julja Burchard; Xudong Dai; Aaron N Chang; Robert L Diaz; Joseph R Marszalek; Steven R Bartz; Michael Carleton; Michele A Cleary; Peter Linsley; Carla Grandori
MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT.
Cell cycle (Georgetown, Tex.) 2009;8(17):2756-68.
2009: Julja Burchard; Aimee L Jackson; Vladislav Malkov; Rachel H V Needham; Yejun Tan; Steven R Bartz; Hongyue Dai; Alan B Sachs; Peter Linsley
MicroRNA-like off-target transcript regulation by siRNAs is species specific.
RNA (New York, N.Y.) 2009;15(2):308-15.
2008: Galina Gabriely; Thomas Wurdinger; Santosh kesari; Christine C Esau; Julja Burchard; Peter Linsley; Anna M Krichevsky
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators.
Molecular and cellular biology 2008;28(17):5369-80.
2008: Irena Ivanovska; Alexey S Ball; Robert L Diaz; Jill F Magnus; Miho Kibukawa; Janell M Schelter; Sumire V Kobayashi; Lee Lim; Julja Burchard; Aimee L Jackson; Peter Linsley; Michele A Cleary
MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression.
Molecular and cellular biology 2008;28(7):2167-74.
2007: Ralf Kittler; Vineeth Surendranath; Anne-Kristin Heninger; Mikolaj Slabicki; Mirko Theis; Gabriele Putz; Kristin Franke; Antonio Caldarelli; Hannes Grabner; Karol Kozak; Jan Wagner; Effi Rees; Bernd Korn; Corina Frenzel; Christoph Sachse; Birte soennichsen; Jie Guo; Janell Schelter; Julja Burchard; Peter Linsley; Aimee L Jackson; Bianca Habermann; Frank Buchholz
Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies.
Nature methods 2007;4(4):337-44.
2007: Peter Linsley; Janell Schelter; Julja Burchard; Miho Kibukawa; Melissa M Martin; Steven Bartz; Jason Johnson; Jordan M Cummins; Christopher K Raymond; Hongyue Dai; Nelson Chau; Michele Cleary; Aimee L Jackson; Michael Carleton; Lee Lim
Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression.
Molecular and cellular biology 2007;27(6):2240-52.
2006: Steven Bartz; Zhan Zhang; Julja Burchard; Maki Imakura; Melissa Martin; Anthony Palmieri; Rachel Needham; Jie Guo; Marcia Gordon; Namjin Chung; Paul Warrener; Aimee L Jackson; Michael Carleton; Melissa Oatley; Louis Locco; Francesca Santini; Todd Smith; Priya Kunapuli; Marc Ferrer; Berta Strulovici; Stephen H Friend; Peter Linsley
Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions.
Molecular and cellular biology 2006;26(24):9377-86.
2006: John Majercak; William Ray; Amy S Espeseth; Adam Simon; Xiao-Ping Shi; Carrie Wolffe; Krista Getty; Shane Marine; Erica Stec; Marc Ferrer; Berta Strulovici; Steven Bartz; Adam Gates; Min Xu; Qian Huang; Lei Ma; Paul J Shughrue; Julja Burchard; Dennis Colussi; Beth L Pietrak; Jason Kahana; Dirk Beher; Thomas W Rosahl; Mark S Shearman; Daria J Hazuda; Alan B Sachs; Kenneth S Koblan; Guy R Seabrook; David J Stone
LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(47):17967-72.
2006: Amy S Espeseth; Qian Huang; Adam Gates; Min Xu; Yuanjiang Yu; Adam J Simon; Xiao-Ping Shi; Xiaohua Zhang; Paul Hodor; David J Stone; Julja Burchard; Guy Cavet; Steven Bartz; Peter Linsley; William Ray; Daria J Hazuda
A genome wide analysis of ubiquitin ligases in APP processing identifies a novel regulator of BACE1 mRNA levels.
Molecular and cellular neurosciences 2006;33(3):227-35.
2006: Dianne S Schwarz; Hongliu Ding; Lori Kennington; Jessica T Moore; Janell Schelter; Julja Burchard; Peter Linsley; Neil Aronin; Zuoshang Xu; Phillip D Zamore
Designing siRNA that distinguish between genes that differ by a single nucleotide.
PLoS genetics 2006;2(9):e140.
2006: Aimee L Jackson; Julja Burchard; Devin Leake; Angela Reynolds; Janell Schelter; Jie Guo; Jason Johnson; Lee Lim; Jon Karpilow; Kim Nichols; William Marshall; Anastasia Khvorova; Peter Linsley
Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing.
RNA (New York, N.Y.) 2006;12(7):1197-205.
2006: Aimee L Jackson; Julja Burchard; Janell Schelter; B Nelson Chau; Michele Cleary; Lee Lim; Peter Linsley
Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity.
RNA (New York, N.Y.) 2006;12(7):1179-87.
2005: Jose M Silva; Mamie Z Li; Kenneth Chang; Wei Ge; Michael C Golding; Richard J Rickles; Despina Siolas; Guang Hu; Patrick J Paddison; Michael R Schlabach; Nihar Sheth; Jeff Bradshaw; Julja Burchard; Amit Kulkarni; Guy Cavet; Ravi Sachidanandam; W Richard McCombie; Michele A Cleary; Stephen J Elledge; Gregory J Hannon
Second-generation shRNA libraries covering the mouse and human genomes.
Nature genetics 2005;37(11):1281-8.
2005: Despina Siolas; Cara Lerner; Julja Burchard; Wei Ge; Peter Linsley; Patrick J Paddison; Gregory J Hannon; Michele A Cleary
Synthetic shRNAs as potent RNAi triggers.
Nature biotechnology 2005;23(2):227-31.
2004: Michele A Cleary; Kristopher Kilian; Yanqun Wang; Jeff Bradshaw; Guy Cavet; Wei Ge; Amit Kulkarni; Patrick J Paddison; Kenneth Chang; Nihar Sheth; Eric Leproust; Ernest M Coffey; Julja Burchard; W Richard McCombie; Peter Linsley; Gregory J Hannon
Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis.
Nature methods 2004;1(3):241-8.
2004: Mao Mao; Matt Biery; Sumire V Kobayashi; Terry Ward; Greg Schimmack; Julja Burchard; Janell Schelter; Hongyue Dai; Yudong D He; Peter Linsley
T lymphocyte activation gene identification by coregulated expression on DNA microarrays.
Genomics 2004;83(6):989-99.
2003: Aimee L Jackson; Steven Bartz; Janell Schelter; Sumire V Kobayashi; Julja Burchard; Mao Mao; Bin Li; Guy Cavet; Peter Linsley
Expression profiling reveals off-target gene regulation by RNAi.
Nature biotechnology 2003;21(6):635-7.
2002: James L Riley; Mao Mao; Sumire Kobayashi; Matt Biery; Julja Burchard; Guy Cavet; Brian P Gregson; Carl H June; Peter Linsley
Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11790-5.
2001: Timothy R Hughes; Mao Mao; A R Jones; Julja Burchard; Matthew J Marton; K W Shannon; S M Lefkowitz; Ziman Michael; Janell Schelter; Michael R Meyer; Sumire V Kobayashi; C Davis; Hongyue Dai; Yudong D He; S B Stephaniants; Guy Cavet; W L Walker; A West; Ernest M Coffey; Daniel D Shoemaker; Roland B Stoughton; A P Blanchard; Stephen H Friend; Peter Linsley
Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer.
Nature biotechnology 2001;19(4):342-7.
2000: Timothy R Hughes; Christopher J Roberts; H Dai; A R Jones; Michael R Meyer; D Slade; Julja Burchard; S Dow; T R Ward; M J Kidd; S H Friend; Matthew J Marton
Widespread aneuploidy revealed by DNA microarray expression profiling.
Nature genetics 2000;25(3):333-7.
1998: Matthew J Marton; Joe L DeRisi; Holly Bennett; Vishwanath R Iyer; Michael R Meyer; C J Roberts; Roland B Stoughton; Julja Burchard; D Slade; H Dai; D E Bassett; Leland H Hartwell; P O Brown; S H Friend
Drug target validation and identification of secondary drug target effects using DNA microarrays.
Nature medicine 1998;4(11):1293-301.